The Plant Cell, Vol. 23: 2581–2591, July 2011, www.plantcell.org ã 2011 American Society of Plant Biologists. All rights reserved.
Distinct Cell-Autonomous Functions of
RETINOBLASTOMA-RELATED in Arabidopsis Stem Cells
Revealed by the Brother of Brainbow Clonal Analysis System W
Guy Wachsman, Renze Heidstra, and Ben Scheres1
Department of Biology, Utrecht University, 3584 CH Utrecht, The Netherlands
Mutations that cause lethality in the gametophyte phase pose a major challenge for studying postfertilization gene function.
When both male and female haploid cells require a functional gene copy, null alleles cause developmental arrest before the
formation of the zygote, precluding further investigation. The Arabidopsis thaliana Rb homolog RE