Quality Assurance by fjzhangxiaoquan

VIEWS: 12 PAGES: 13

									UWI BIOCHEMISTRY - BC35F
QUALITY ASSURANCE




                           Prepared by
                           A. E. Waite
QUALITY ASSURANCE – BC35F
TERMS USED IN QUALITY ASSURANCE


  –   Quality              – Objective Evidence
  –   Quality Control      – Acceptance
  –   Quality Assurance      Sampling
  –   Quality Manual       – Conformity
  –   Quality Planning     – Corrective Action
  –   Customer             – Preventive Action
  –   Inspection           – Control Limits
  –   Specifications       – Standards
  –   Acceptable Quality   – Validation
      Levels
QUALITY ASSURANCE – BC35F


Requirements for a successful QA Programme:

• Management Commitment to Quality
   – Provision of resources
   – Overall support

• Co-operation and involvement by staff (“Buy-
  In”)
• Clearly Defined Objectives
QUALITY ASSURANCE – BC35F


Factors to be Considered in the QA
  Programme:
  –   Quality of Raw Material
  –   Manufacturing processes
  –   Product Specification
  –   Statutory Regulations
  –   Equipment and other Resources
QUALITY ASSURANCE – BC35F

Responsibilities
   –   Inspection and Testing
   –   References & Control
   –   Accuracy of Test Results
   –   Record Keeping
   –   Timely Dispatch of Results
   –   Certificates of analysis/Conformance
   –   Identification of Quality Defects
   –   Correction of Quality Defects
   –   Prevention of Defects
QUALITY ASSURANCE – BC35F


Support Activities
  –   Market Surveys
  –   Packaging Considerations
  –   Storage Facilities
  –   Maintenance of Manufacturing Equipment
QUALITY ASSURANCE – BC35F
 QUALITY ASSURANCE – BC35F
   FLOWCHART SHOWING MANUFACTURE OF ALCOHOLIC BEVERAGES                                  PRODUCT




 Substrate                        Carbon
                                                               Filtration                Vodka
preparation                      Treatment


Fermenta                                                                                 Unage
              Distillation       Blending        Filtration
   tion                                                                                  d Rum



                                                               Carbon          Chill
                             Aging          Blending                                       Aged
                                                              Treatment     filtration
                                                                                           Rum

                                                                             Colour
                                                                            and Filter
                              Flavour or                                                     Gin
                             concentrate
                               addition



                   Flavour                    Colour                                       Wine
  Fining
                   additon                    Filter
QUALITY ASSURANCE – BC35F

Inspection and Testing
   – Raw material
      • Grape juice, ginger, coffee, botanicals, pimento, honey,
        sugar, caramel, flavours (A & N) colouring agents, chemicals
        (treatment, cleaning)
   – Water
      • Source (city, wells)
      • Treatment ( Softening, deionization, reverse osmosis)
      • Analyses
          –   Conductivity
          –   pH
          –   Sensory
          –   chlorine
   – Product
QUALITY ASSURANCE – BC35F
QA Analyses – Product
• Measurement of
    –   Alcoholic strength
    –   Colour
    –   Turbidity
    –   Specific gravity/brix
    –   Acidity
    –   Metabislufite
•   Organoleptic/Sensory Evaluation
•   Stress Tests
•   Microbiology
•   Gas Chromatography
QUALITY ASSURANCE – BC35F

EQUIPMENT
  – Routine maintenance
  – Calibration programme
  – Use and safeguard of instruments against
    accidental change in status
  – Re-testing when instruments are found out of
    calibration
  – Standardization of reagents
  – Establishing shelf life
QUALITY ASSURANCE – BC35F


Statistical Tools
  – Sampling Plans
  – Control Charts
Quality Audits and System Review
  – Product
  – Process
  – System
       QUALITY ASSURANCE – BC35F


Quality Assurance Personnel
  –   Quality Assurance Manager
  –   QA Co-ordinator
  –   QA Supervisor
  –   QA Analyst
  –   Laboratory Technician
  –   Laboratory Assistant

								
To top