Policy for Guidelines for the Decontamination of Equipment

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							         Policy for the Management of Clostridium difficile
                     Associated Disease (CDAD)
                                                   IC0011


Version Number:                       5

Issue Date:                           29 June 2011

Review Date:                          April 2014



Sponsoring Director:                  Director of Public Health
                                      NHS County Durham and Darlington

Prepared By:                          Lead Infection Prevention and Control Nurse

Consultation Process:                 Members of NHS County Durham and Darlington
                                      Infection Control Committee

Formally approved on behalf of the Board by the Infection Control Committee 11
April 2011.

Document History

Version        Date              Significant Changes
2              Nov 2006          *
3              Nov 2008          *
4              April 2009        To incorporate new DoH guidance on management of
                                 Clostridium difficile
5              April 2011        Reviewed

POLICY VALIDATION STATEMENT

This policy is due for review on the latest date shown about.
After this date, policy and process documents may become invalid.
Policy users should ensure that they are consulting the current valid version
of the documentation.




H:Policy Development/Infection Control/IC0011v5                            Page 1 of 25
Equality Impact Assessment Statement


Audit Assessment               Date               Result

Risk Audit                     04.03.2011         Risks identified and risk assessment included
                                                  at Appendix 8

Equality Audit                 04.03.2011         No or very low potential for discrimination

Human Rights Audit             04.03.2011         No breach of Human Rights




H:Policy Development/Infection Control/IC0011v5                                Page 2 of 25
 POLICY FOR MANAGEMENT OF CLOSTRIDIUM DIFFICILE
            ASSOCIATED DISEASE (CDAD)

                                                  Contents
  Section                                           Title                         Page
        1             Introduction                                                  4

        2             Definitions                                                   4

        3             Clostridium difficile Associated Disease                      5

        4             Duties and Responsibilities                                   7

        5             Implementation                                                9

        6             Training Implications                                         9

        7             Documentation                                                 9

        8             Monitoring, Review and Archiving                              10

        9             Equality Impact Assessment Statement                          11

Appendices
        1             Examples of death certification for CDI patients              15

        2             Bristol Stool Form Scale                                      16

        3             Medicines that can produce diarrhoea                          17

       4/5            Treatment Algorithms                                        18/19

        6             Clostridium difficile – Fact Sheet                            20

        7             Risk Assessment                                               25




H:Policy Development/Infection Control/IC0011v5                          Page 3 of 25
       POLICY FOR THE MANAGEMENT OF CLOSTRIDIUM
           DIFFICILE ASSOCIATED DISEASE (CDAD)

1.       Introduction
         NHS County Durham and Darlington aspires to the highest standard of
         corporate behaviour and clinical competence, to ensure that safe, fair and
         equitable procedures are applied to all organisational transactions, including
         relationships with patients, their carers, public, staff, stakeholders and the use
         of public resources. In order to provide clear and consistent guidance, NHS
         County Durham and Darlington will develop documents to fulfill all statutory,
         organisational and best practice requirements and support the principles of
         equal opportunity for all.

         The aim of this policy is to provide a framework for the effective management
         of patients with Clostridium difficile associated disease.

         This policy is in line with national guidance from the Department of Health.

1.1      Status
         This policy is an Infection Control policy.

1.2      Purpose and Scope
         To ensure that patients are managed safely and effectively in order to reduce
         cross infection and sustained illness.

         This policy applies to all health care workers working within NHS County
         Durham and Darlington. It would be good practice for this policy to be
         adopted by independent contractors.

         ACCESSING ADVICE AND GUIDANCE – Advice and/or guidance on
         infection control issues can be obtained by contacting the Infection Prevention
         and Control Department between 8.30am – 5.00pm Monday to Friday.

         Advice is also available on the NHS County Durham and Darlington internet
         site www.cdd.nhs.uk (then type ‘infection control’ into top right hand search
         box), and on the support zone.

2.       Definitions
         Clostridium difficile Associated Disease – occurs when the normal bacteria of
         the bowel are altered allowing Clostridium difficile to flourish and produce
         toxins.




H:Policy Development/Infection Control/IC0011v5                       Page 4 of 25
3.       Clostridium difficile Associated Disease

3.1      Clostridium difficile are anaerobic, gram-positive, spore forming bacilli. The
         spores are resistant to exposure to air, drying, and heat and can survive in the
         environment.

         Clostridium difficile Associated Disease (CDAD) occurs when the normal
         bacteria/flora of the bowel are altered allowing Clostridium difficile to flourish
         and produce toxin A and/or B.

         The primary cause of CDAD is antibiotic exposure. Gastro-intestinal surgery
         can also increase a person’s risk of developing the disease. A long length of
         stay in healthcare settings and immuno-suppression leads to an increase in
         patients who are carriers.

         All age groups can be affected: however, the elderly are most at risk. Over
         80% of cases are reported in the over 65 age group. Children under the age
         of 2 years are not usually affected.

3.2      Clinical Features

             The illness ranges from mild self-limiting diarrhoea to explosive watery and
              foul smelling diarrhea.
             Symptoms are often associated with antibiotic therapy.
             The patient may also have fever and abdominal cramps.
             Occasionally Clostridium difficile can lead to potentially fatal pseudo
              membranous colitis and perforation of the bowel.

3.3      Definition of Clostridium difficile Diarrhoea
         One episode of diarrhoea, defined either as stool loose enough to take the
         shape of a container used to sample it or as Bristol Stool Chart types 5-7
         (Appendix 2) that is not attributable to any other cause, including medicines
         (Appendix 3), and that occurs at the same time as a positive toxin assay (with
         or without a positive C difficile culture) and/or endoscopic evidence of pseudo
         membranous colitis.

         Testing

         Re-testing of cases will not be carried out within 28 days. Testing will not be
         carried out in general on children under two years of age.

         More than one test per patient may be required: if the first test is negative but
         where there is a strong clinical suspicion of CDI, retest a second sample 24
         hours later.

3.4      Transmission


H:Policy Development/Infection Control/IC0011v5                         Page 5 of 25
             Various studies show that 2-3% of healthy adults and up to 36% of
              hospitalised patients harbour Clostridium difficile in their faecal flora.
             Direct spread from patient to patient by faecal oral route.
             Direct spread through the hands of healthcare workers.
             Indirect spread from the patient to the environment and from the
              environment to the patient.

3.5      Care of Patients at Home

3.5.1 On confirmation of a Clostridium difficile positive stool result GPs
      should:

             Communicate with relevant personnel involved with patient care.
             Review patient’s general condition.
             Stop any existing antibiotics if possible.
             Ensure no laxative or anti-diarrhoeal treatment is prescribed.
             Drug therapy – antibiotic as indicated depending on disease severity
              shown on the Daily Scorecard (Appendix 4). If the patient’s condition does
              not improve after 3 days or there is clinical deterioration contact
              Consultant Microbiologist at appropriate hospital for further advice.
              Metronidazole syrup is not effective in treating Clostridium difficile if the
              patient is on Proton Pump Inhibitors. Treatment Algorithm can be found in
              Appendices 5 and 6.
             A patient and carers’ information leaflet is available and can be located on
              the PCT’s website (intranet and external Internet).

3.5.2 Infection Control Measures:

             Encourage thorough hand washing with soap and water after personal
              care by everyone involved, and by patient before meals and after using the
              toilet.

             Soiled clothing or bedding to be washed at the highest possible
              temperature.

             Clean the toilet and bathing facilities following each use using a bleach-
              based product.

             Healthcare workers delivering care – any gloves and aprons to be
              disposed of with wipes/pads, etc as hazardous waste.

             Once the diagnosis is confirmed, no further specimens are required unless
              another cause of diarrhoea is suspected.

3.5.3 Any primary cause of death resulting from Clostridium difficile must be
      reported to the Strategic Health Authority as an Untoward Incident
       (Appendix 1).



H:Policy Development/Infection Control/IC0011v5                           Page 6 of 25
4.       Duties and Responsibilities including the risks
         associated with not recognising or treating
         Clostridium difficile Associated Disease
4.1      Trust board
         The Board has delegated authority to the Joint Board (JB) for setting the
         strategic context in which organisational process documents are developed,
         and for establishing a scheme of governance for the formal review and
         approval of such documents.

4.2      Chief executive
         The Joint Chief Executive has overall responsibility for the strategic direction
         and operational management, including ensuring that Trust process
         documents comply with all legal, statutory and good practice guidance
         requirements.

4.3      Director of Public Health
         As the nominated director responsible for Infection Prevention and Control the
         Director of Public Health has delegated responsibility for ensuring that
         arrangements are in place to manage Infection Prevention and Control
         including the risks from Clostridium difficile Associated Disease.

         In addition the Director of Public Health is responsible for ensuring that the
         policy is drafted, approved and disseminated in accordance with ‘Writing
         Policy Documents’.

         The necessary training and education needs and methods to implement this
         document are identified and resourced. Mechanisms are in place for the
         regular evaluation of the implementation and effectiveness of this document.

4.4      Lead Infection Prevention and Control Nurse
         The Lead Infection Prevention and Control Nurse will:

             generate and formulate this policy, identifying appropriate processes for
              regular evaluation of, and the implementation and effectiveness of, this
              policy;

             notify the Policy Coordinator of any revisions to this document;

             ensure the policy is taken to members of NHS County Durham and
              Darlington Infection Control Committee for comment and approval;

             arrange for superseded version of this document to be retained in line with
              national guidance.

H:Policy Development/Infection Control/IC0011v5                       Page 7 of 25
4.5      Senior Infection Prevention and Control Nurse
         The Senior Infection Prevention and Control Nurse will:

             update the policy and all supporting documents;

             notify the Infection Control Committee should any update to this policy be
              required;

             monitor the effectiveness of this policy and its procedures through audit.

             provide support and advice to staff on decontamination of equipment;

             deliver training to clinical staff on the procedures and processes laid out in
              the policy through training.

4.6      Infection Prevention and Control Team
         The Infection Prevention and Control Team will:

             monitor the effectiveness of this policy and its procedures through audit;

             provide support and advice to staff on decontamination of equipment;

             deliver training to clinical staff on the procedures and processes laid out in
              the policy through training.

4.7      All staff
         All staff, including temporary and agency staff, are responsible for:

             compliance with relevant process documents. Failure to comply may
              result in disciplinary action being taken;

             co-operating with the development and implementation of polices and
              procedures as part of their normal duties and responsibilities;

             identifying the need for a change in policy or procedure as a result of
              becoming aware of changes in practice, changes to statutory
              requirements, revised professional or clinical standards and local/national
              directives, and advising their line manager accordingly;

             identifying training needs in respect of policies and procedures and
              bringing them to the attention of their line manager;

             attending training/awareness sessions when provided.



H:Policy Development/Infection Control/IC0011v5                         Page 8 of 25
5.       Implementation
5.1      This policy will be available to all staff caring for or managing patients with
         Clostridium difficile Disease.

5.2      All directors and managers are responsible for ensuring that relevant staff
         within their own directorates and departments have read and understood this
         document and are competent to carry out their duties in accordance with the
         procedures described.

6.       Training Implications
         The sponsoring director will ensure that the necessary training or education
         needs and methods required to implement the policy or procedure(s) are
         identified and resourced or built into the delivery planning process. This may
         include identification of external training providers or development of an
         internal training process.

         The training required to comply with this policy is through attendance at
         Infection Control mandatory training.

7.       Documentation
7.1      Other relevant policies

         None.

7.2      Legislation and statutory requirements
         None.

7.3      Best practice documents
         None.

7.4      References
         Department of Health (2005). Saving Lives: a delivery programme to reduce
         health care associated infection (HCAI) including MRSA. London. DH.

         Department of Health and HPA (2008) Clostridium difficile infection: How
         to deal with the problem. London. DH

         Department of Health and Public Health service laboratory Service (1994)
         Clostridium difficile infection: prevention and management: a report by
         the joint DH/PHLS Working Group. London. DH.



H:Policy Development/Infection Control/IC0011v5                        Page 9 of 25
         Department of Health. (2005) PL/CMO/2005/6, PLCMO2005/5 Gateway No.
         5954 Infection caused by Clostridium difficile. London. DH.

         Department of Health. (2011) Diagnostic testing for Clostridium difficile
         infection Gateway No. 15766. London. DH.

         Healthcare Commission (2005). Management prevention and surveillance of
         Clostridium difficile interim findings from a National Survey of NHS acute
         trusts in England London Health Protection Agency and Commission for
         Healthcare Audit and Inspection.

         Standards Unit and Department for Evaluations, Standards and Training (2010).
         Investigation of faeces specimens for bacterial pathogens. DEST Issue No 7.

         The Health and Social Care Act 2008 Code of Practice for the NHS on the
         prevention and control of healthcare associated infections and related
         guidance. London. DH.

8.       Monitoring, Review and Archiving

8.1      Monitoring

         The Director of Public Health, as sponsor director, will agree with the Lead
         Infection Prevention and Control Nurse a method for monitoring the
         dissemination and implementation of this policy. Monitoring information will
         be recorded in the policy database.

8.2      Review
8.2.1 The Director of Public Health will ensure that each policy document is
      reviewed in accordance with the timescale specified at the time of approval.
      No policy or procedure will remain operational for a period exceeding
      three years without a review taking place.

8.2.2 Staff who become aware of changes in practice, changes to statutory
      requirements, revised professional or clinical standards and local/national
      directives that affect, or could potentially affect policy documents, should
      advise the sponsoring director as soon as possible, via line management
      arrangements. The sponsoring director will then consider the need to review
      the policy or procedure outside of the agreed timescale for revision.

8.2.3 If the review results in changes to the document, then the initiator should
      inform the policy manager who will renew the approval and re-issue under the
      next ‘version’ number. If, however, the review confirms that no changes are
      required, the title page should be renewed indicating the date of the review
      and date for the next review and the title page only should be re-issued.

8.2.4 For ease of reference for reviewers or approval bodies, changes should be
      noted in the ‘document history’ table on the front page of this document.

H:Policy Development/Infection Control/IC0011v5                   Page 10 of 25
         NB If the review consists of a change to an appendix or procedure document,
         approval may be given by the sponsor director and a revised document may
         be issued. Review to the main body of the policy must always follow the
         original approval process.

8.3      Archiving
         The Policy Manager will ensure that archived copies of superseded policy
         documents are retained in accordance with Records Management: NHS Code
         of Practice 2008.

9.       Equality Impact Assessment Statement
         The tables below summarise reviews with respect to:

                  Strategic and operational risks, including risks to health and safety.
                  Current equality and diversity legislation.
                  Rights under the European Convention on Human Rights.




H:Policy Development/Infection Control/IC0011v5                         Page 11 of 25
9.1      Risk Audit

Risk Audit for
                                                                          Significant Risks
RISK CATEGORIES
                                                                          Identified Yes/No
1        Risks relating to organisational objectives                      Yes
2        Risks to patient experience/outcome                              Yes
3        Risk to or from service/business interruption                    No
4        Risks relating to staffing and competence                        Yes
5        Financial risks                                                  No
6        Risks to compliance with inspection/audit standards              Yes
7        General risks to organisational reputation                       Yes
8        Specific health and safety (inc fire) risks to persons
         (staff, patients, public, etc)
         a       Location (access, environment, working                   No
                 conditions)
         b       Equipment (medical, electrical, other)                   No
         c       Hazardous substances
         d       Lone working                                             No
         e       Moving and handling                                      No
         f       Potential to cause undue stress                          No
         g       Anti-social behaviour (violence, harassment,             No
                 theft)
OUTCOME (tick appropriate box)                    ACTION
No significant risks                              Proceed with ratification process.
identified
Significant risks identified                     Complete a full risk assessment form and
                                                  action plan for all risks identified. Include in
                                                  the Appendices – see Appendix 8.
There is some doubt about                         Take further advice from appropriate
whether risks are significant                     directorate or department. If unresolved,
or relevant.                                      refer to Governance and Assurance
                                                  Committee.




H:Policy Development/Infection Control/IC0011v5                              Page 12 of 25
9.2      Equality Audit

Equality Audit for

QUESTION                                                             RESPONSE
What is the purpose of the proposed policy document                  Management of Patients
(or changes to policy document)?                                     with Clostridium difficile
                                                                     Associated Disease
Who is intended to benefit, and how?                                 Correct patient
                                                                     management and safety
Will the proposals involve, or have consequences for,                No
the people the PCT serves and employs?
Is there any reason to believe that people could be                  No
affected differently by the proposals, for example in
terms of access to a service, or the ability to take
advantage of proposed opportunities?
Is there any evidence that any part of the proposals                 No
could discriminate unlawfully, directly or indirectly,
against any section of the population?
Is the proposed policy likely to affect relations between            No
certain groups of people, for example because it is
seen as favouring a particular group or denying
opportunities to another?
Is the proposed policy likely to damage relations                    No
between any particular group(s) of people and the
PCT?
OUTCOME (tick appropriate box)
Potential for discrimination                     Proceed with ratification process.
is very low or non-existent
Potential for discrimination                      Amend the document as appropriate to
exists                                            clarify exceptions or remove potential. If this
There is doubt about the                          is not possible, take further advice from
potential for discrimination                      Corporate Services Manager and/or the
                                                  Equality Lead Manager (HR Department)




H:Policy Development/Infection Control/IC0011v5                             Page 13 of 25
9.3      Human Rights Audit

Human Rights Audit for

QUESTION                                                             RESPONSE
Does the policy document interfere with a Convention                 No
right?
Could the actions described in the policy document                   No
touch on one of the Convention rights?
Is there a victim?                                                   No
Are there circumstances where the right can                          No
legitimately be limited or interfered with?
Does the interference meet the general criteria                      No
established by the Strasbourg authorities, ie:
              The action is prescribed by law
              It pursues a legitimate aim.
              It is necessary in a democratic society.
OUTCOME (tick appropriate box)
No rights affected                               Proceed with ratification process.
Potential to affect a right                       Amend the document as appropriate to
has been identified                               clarify exceptions or remove potential. If this
There is doubt about the                          is not possible, take further advice from
potential to affect a right.                      Corporate Services Manager/Legal Advisers.




H:Policy Development/Infection Control/IC0011v5                            Page 14 of 25
                                                                           APPENDIX 1



Examples of death certification for CDI patients

(Modified from the November 2007 version of Guidance for doctors certifying cause
of death in England and Wales, www.gro.gov.uk/medcert

If a healthcare-associated infection (HCAI) was part of the sequence leading to
death, it should be in Part 1 of the certificate, and you should include all the
conditions in the sequence of events back to the original disease being treated.

Examples:
Ia. Clostridium difficile pseudomembranous colitis
Ib. Multiple antibiotic therapy
Ic. Community-acquired pneumonia with severe sepsis
II. Immobility, polymyalgia rheumatica, osteoporosis

If your patient had an HCAI which was not part of the direct sequence, but which you
think contributed at all to their death, it should be mentioned in Part 2 of the
certificate.

Examples:
Ia. Bronchopneumonia
Ib. Carcinomatosis and renal failure
Ic. Adenocarcinoma of the prostate
II. Clostridium difficile infection secondary to antibiotic therapy for recurrent
bronchopneumonia




H:Policy Development/Infection Control/IC0011v5                      Page 15 of 25
APPENDIX 2




         The Bristol Stool Form Scale
                                                  Type 1
                                                  Separate hard lumps, like nuts (hard to pass)



                                                  Type 2
                                                  Sausage-shaped but lumpy



                                                  Type 3
                                                  Like a sausage but with cracks on its surface



                                                  Type 4
                                                  Like a sausage or snake, smooth and soft



                                                  Type 5
                                                  Soft blobs with clear-cut edges (passed easily)



                                                  Type 6
                                                  Fluffy pieces with ragged edges, a mushy stool




                                                  Type 7
                                                  Watery, no solid pieces ENTIRELY LIQUID




H:Policy Development/Infection Control/IC0011v5                             Page 16 of 25
                                                                          APPENDIX 3


Medicines that can produce diarrhoea

Diarrhoea is a common adverse drug reaction (ADR) with many medicines.
Antimicrobials account for about 25% of drug-induced diarrhoea though most cases
are benign (Lee, 2006).

While diarrhoea has been seen with most medicines, the ones that are most
commonly implicated are:

         •         acarbose
         •         antimicrobials
         •         biguanides
         •         bile salts
         •         colchicine
         •         cytotoxics
         •         dipyridamole
         •         gold preparations
         •         iron preparations
         •         laxatives
         •         leflunomide
         •         magnesium preparations, eg antacids
         •         metoclopramide
         •         misoprostol
         •         non-steroidal anti-inflammatory drugs (NSAIDS), eg aspirin, ibuprofen
         •         olsalazine
         •         orlistat
         •         proton pump inhibitors; and
         •         ticlopidine

Alternative diagnoses for the diarrhoea are important; therefore, careful attention
should be paid to the temporal relationship between the time that the medicine is first
taken and when the diarrhoea first appears.

Further information on adverse effects is available from local medicines information
centres or by using the ‘search by section’ facility at http://emc.medicines.org.uk/




H:Policy Development/Infection Control/IC0011v5                      Page 17 of 25
                                                    APPENDIX 4




H:Policy Development/Infection Control/IC0011v5   Page 18 of 25
                                                      APPENDIX 5




H:Policy Development/Infection Control/IC0011v5   Page 19 of 25
                                                                            APPENDIX 6

                  CLOSTRIDIUM DIFFICILE – FACT SHEET

What is Clostridium difficile?
        Clostridium difficile (C diff) are gram-positive, anaerobic, spore forming bacilli.
         The spores are resistant to exposure to air, drying and heat, and can thereby
         survive in the environment.

        Patients may be colonised with C diff but exhibit NO clinical symptoms.

        Clostridium difficile infection (CDI) generally occurs as a result of disruption of
         gut flora and loss of colonisation resistance, usually following antibiotic
         treatment.

        CDI symptoms is due to toxins produced by C Diff which attack the gut wall. It
         is this toxin which is detected in the laboratory test for C Diff.

CDI

Clinical Features
        Diarrhoea ranging from mild self-limiting diarrhoea to a severe illness with
         explosive, watery and foul smelling diarrhoea.
        Fever.
        Loss of appetite.
        Nausea.
        Abdominal pain/tenderness.
        Symptoms are associated with antibiotic therapy.

Risk Factors
All age groups can be affected but the over 65-age group are the most at risk, and
risk increases further with:

        Antibiotic exposure – most common cause of CDI.
        Gastrointestinal surgery.
        Length of stay in healthcare inpatient environment.
        A serious underlying illness.
        Immunocompromising conditions.
        Most infections occur in hospitals, community hospitals and care homes but
         they can also occur in primary care settings.




H:Policy Development/Infection Control/IC0011v5                       Page 20 of 25
How Do Patients Become Infected?
        Patients usually become colonised with Clostridium difficile during a stay in a
         healthcare facility, although community acquisition does occur.

        Normal bowel bacteria provide protection against pathogenic organisms
         including Clostridium difficile, this is known as colonisation resistance. When
         a patient is exposed to antibiotics this disrupts the bowel flora which permits
         Clostridium difficile to flourish. Clostridium difficile produces toxins which
         damage the cells lining the intestines leading to CDI.

        Cross-infection:

                  Faecal/oral route, either direct person to person, via healthcare
                   workers, or via a contaminated environment.

                  Large numbers of spores are excreted in liquid faeces and can survive
                   for long periods of time in the environment.

                  Contamination of the patient’s immediate general environment can
                   occur, including all horizontal surfaces, curtains, bedding, commodes
                   and equipment; toilet areas, bedpan washers and dirty utility areas.

Prevention

        Appropriate prescribing within the antimicrobial formulary.

        Implement measures to prevent cross infection.

Protocol for Diagnosis
All patients with unexplained diarrhoea (frequent, loose unformed stools unusual to
that patient):
.
       Collect stool specimen, ensuring there is enough sample to ¼ fill the
        specimen pot.

        Specimens to Darlington Memorial Hospital and University Hospital of North
         Durham use the microbiology form and request:

                  microscopy, culture and sensitivity.




H:Policy Development/Infection Control/IC0011v5                        Page 21 of 25
Clostridium difficile infection should be managed as a diagnosis in its own right, the
following mnemonic protocol (SIGHT) can be used when managing suspected
potentially infectious diarrhoea within an inpatient setting.

         S         Suspect that a case may be infective where there is no clear alternative
                   cause for diarrhoea

         I         Isolate the patient and consult with the infection control team (ICT)
                   while determining the cause of the diarrhoea

         G         Gloves and aprons must be used for all contacts with the patient and
                   their environment

         H         Hand washing with soap and water should be carried out before and
                   after each contact with the patient and the patient’s environment

         T         Test the stool for toxin, by sending a specimen immediately

All healthcare workers and GPs must recognise and report to the HPA a potential
outbreak situation within a care home setting.

Any patient with a diagnosis of CDI as major cause of death appearing on part 1 of
the death certificate must be reported as a Serious Untoward Incident.


MANAGEMENT PROTOCOL

Patient No Longer Symptomatic
        Do not commence antibiotic therapy and observe.

For Symptomatic Patients
Patient at Home

        Communicate with relevant personnel involved with patient care. A patient
         and carers information leaflet is available from www.countydurham.nhs.uk
        Review patient’s general condition.
        Stop any existing antibiotics if possible.
        Ensure no laxative or anti-diarrhoeal treatment is prescribed
        Drug therapy: Metronidazole 400mg. Eight hourly orally for 10 days, then
         stop. If the patient’s condition does not improve after 3 days or there is
         clinical deterioration contact Consultant Microbiologist at appropriate hospital
         for further advice. Metronidazole syrup is not effective in treating CDI if the
         patient is on Proton Pump Inhibitors.

If the patient requires admission to an inpatient facility ensure all relevant personnel
are made aware of the patient’s C diff result.



H:Policy Development/Infection Control/IC0011v5                        Page 22 of 25
Infection Control Measures

        Encourage thorough hand washing with soap and water after personal care
         by anyone involved, and by patient before meals and after using the toilet.
        Soiled clothing or bedding to be washed at the highest possible temperature.
        Clean the toilet and bathing facilities following each use using a bleach-based
         product.
        Healthcare workers delivering care – hand washing with soap and water,
         alcohol gel cannot be relied upon to decontaminate hands in this
         circumstance; gloves and aprons to be worn and disposed of with any
         wipes/pads etc. as hazardous waste.
        Once the diagnosis is confirmed no further specimens are required unless
         another cause of diarrhoea is suspected or symptoms re-occur after 28 days.

Patient in Care Home Facility

        Management as above.
        The patient’s diarrhoea to be monitored preferably using the Bristol Stool
         Chart.

Infection Control Measures

        Immediately confine patient to a room preferably with own toilet or commode
         and implement isolation procedures to prevent cross infection. It is important
         to physically separate the symptomatic patient from other vulnerable residents
         in order to prevent the spread of CDAD.
        All visitors to be advised of any necessary precautions and encouraged not to
         perform any personal care.
        Hand hygiene – staff and relatives must observe strict hand washing procedures
         with soap and water, before and after each patient contact and with the
         immediate environment.
        Residents should be encouraged to wash hands before meals and after using
         the toilet.
        Personal Protective Equipment – disposable gloves and aprons should be worn
         for direct care of the patient. These should be removed and disposed of as
         hazardous waste immediately following the episode of care, and then hand
         hygiene performed.
        Laundry – should be categorised as infected. Soiled clothing or bedding should
         be washed according to local protocol.
        Staff to check the integrity of mattress covers.
        Any equipment, for example slings/hoists should be allocated to individual
         residents and thoroughly cleaned before and after each use.
        Environmental cleaning – must be completed daily.
        Horizontal surfaces should be cleaned with detergent and water then
         disinfected with 1,000 ppm hypochlorite or local alternative chlorine
         based agent.
        Particular attention must be paid to all contact surfaces such as tables, chairs,
         door handles etc.



H:Policy Development/Infection Control/IC0011v5                     Page 23 of 25
        Toilet seats or commodes must be thoroughly cleaned after each use.
         Commode liners preferably to be heat disinfected in a mechanical washer or
         washed in a designated area with detergent and water followed by a disinfectant
         and disposable cloths to be used.
        If the patient requires transfer to hospital ensure all relevant personnel are
         informed of patient’s C diff result.
        Once the patient has been symptom free for 48 hours isolation precautions can
         cease and the room to be terminally cleaned.
        Following a confirmed diagnosis no further specimens are required unless
         another cause of diarrhoea is suspected, or symptoms reoccur after 28 days.


NB

NHS Co Durham and NHS Darlington Infection Control Team will be informed of any
patients diagnosed with CDI. Contact with the care home will be made and practical
support will be offered from the team including a care pathway. A root cause analysis
will then be completed.

Advice can be sought from the Infection Control Team on 0191 333 3320.




H:Policy Development/Infection Control/IC0011v5                    Page 24 of 25
                                                                          APPENDIX 7
There is a risk of non-compliance with all infection control policies which would in turn
increase the risk of patients acquiring healthcare associated infections (HCAI), the
organisation not achieving national targets on HCAI and not complying with inspection
audits.

These policies are designed to provide a framework to reduce those risks.




H:Policy Development/Infection Control/IC0011v5                     Page 25 of 25

						
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