Randox Pharma Services pushes the boundaries of Biomarker Discovery

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					May 10, 2011 - Health

Randox Pharma Services

Randox Pharma Services pushes the boundaries of
Biomarker Discovery
Randox has unrivalled in-house technical know-how, in the
manufacture of the highest quality clinical diagnostic reagents.

                              Despite already supplying over 400 biomarker assays
                              from their current product portfolio, Randox Pharma
                              Services are investing to develop solutions for biomarker
                              discovery, given their broad range of applications from
                              the diagnosis, prognosis and monitoring of disease
                              progression through to the monitoring of clinical
responses to a therapeutic intervention and personalised medicine.

Currently biomarker discovery by mass spectrometry is an expensive and laborious
method, with limitations in reproducibility and sensitivity due to the wide range of
protein concentrations in plasma and extensive processing requirements. Biomarker
validation and follow-on studies can also be impeded by a lack of available
immuno-affinity reagents.

In response to these limitations, the recently developed QuantiPlasma Array from
Randox is a monoclonal antibody microarray designed to assess the level of multiple
proteins simultaneously in human plasma. Each kit contains 300 unique monoclonal
antibodies, so by using the QuantiPlasma Array it is possible to directly assess the
plasma proteome dynamics of normal and disease state plasma samples for
identification of novel biomarkers in conjunction with Randox’s Biochip Array
Technology analyser platform.

With such innovative solutions Randox Pharma Services is working to help meet the
pressing need for biomarker discovery in a cost effective manner and ultimately enable
their translation to new diagnostic solutions and improved healthcare.

For more information please visit http://www.randoxpharmaservices.com or email

About Randox Pharma Services
In recognition of the vital role biomarkers play in drug development programmes,
Randox Pharma Services offer a comprehensive range of solutions, allowing Pharma
R&D to become more efficient, cost effective and safer. Biochip Array Technology, a
revolutionary multiplexing technology, enables multiple biomarker results from a single
sample. Over 120 enzymatic, substrate and immunoturbidimetric assays are available
for use on our range of world class clinical chemistry analysers while our QC range
provides essential performance checks and traceability. We can even provide a tailor
made solution to fulfil your requirements. Randox Pharma Services support every stage

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of the clinical trial process.

Over the past 3 decades, Randox Pharma Services has been supplying the world’s
leading CRO’s Pharmaceutical and Biotech companies and has built up unrivalled
in-house technical know-how, whether in the development of new biomarker assays,
companion diagnostics or the manufacture of the highest quality clinical diagnostic
reagents and fully customised human and animal quality control sera and calibrators -
That’s why our products are utilised by 60,000 customers in 130 countries!

As reducing costs, without comprising on quality is of paramount importance in the
current climate, Randox Pharma Services are uniquely positioned to offer a full package
from pre-clinical diagnostic solutions through to the customised development of
companion diagnostics.

Randox Pharma Services expertise, state-of-the-art manufacturing facilities and highly
specialised scientists enable us to provide a service and product tailored to a specific
R&D of clinical trial requirement.

‘Personalised medicine deserves a personalised approach!’

For more information on our Randox Pharma Services products, Contract Manufacturing
or Custom Biomarker Development, please contact us directly or e-mail

Shane Mc Guigan
Randox Pharma Services

Crumlin, Antrim
United Kingdom BT29 4QY

Voice: +44 (0) 28 9442 2413
Fax: +44 (0) 28 9445 2912

Website: http://www.randox.com
Twitter: http://twitter.com/#!/RandoxLabs
Facebook: http://www.facebook.com/RandoxLabs

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