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Award Recipient Sponsor Title/Description Amount





Sandra Alber Michigan Maybury + OU = Mas Mathematics $ 168,387

School of Department of por Todos. Maybury Cultural School, a

Education and Education Detroit Public School, struggles with the

Human Services critical need to prepare poor,

underrepresented students for success

in business and industry. This project

couples Maybury School and Oakland

University to address the pressing

needs of teachers for high quality,

sustained, and focused professional

development to increase students'

mathematics achievement.









Sitamarayya Ari National Cyclic GMP Signaling Pathways in $ 355,000

Eye Research Institutes of Retina. The objective of this study is to

Institute Health understand how nitric oxide brings

about the changes in the permeability

of retinal gap junctions. Preliminary

studies have already established the

presence of nitric oxide and cyclic GMP-

activated phosphorylation of several

proteins in bovine retina, validating the

hypothesis. Successful completion of

this research will establish the

biochemical mechanism of cyclic GMP

action in light adaptation and identify

the proteins that mediate its effects.

Award Recipient Sponsor Title/Description Amount





Karen Bolak Central Arts Related to Teaching Standards. $ 19,079

School of Michigan This program will provide professional

Education and University development for 25 Pontiac Middle

Human Services School teachers during a one week

workshop in July 2003, and four follow-

up sessions in the fall of 2003. This

project is a joint program with Michigan

School in the Middle at Central

Michigan University. The summer

workshop will focus on increasing

teachers' content knowledge,

increasing their understanding of state

and national content standards in the

arts, social studies, mathematics,

language arts, and science, and

increasing their understanding of

utilizing the instructional strategies

which are most effective in teaching

young adolescents.









Shravan Chintala National Retinal Ischemia-Induced MMPs and $ 284,000

Eye Research Institutes of Ganglion Cell Death. The long-term

Institute Health goal of this project is to study the

molecular mechanisms underlying

ganglion cell death in an in vivo model

of retinal ischemia, focusing on the role

of matrix metalloproteinases (MMPs)

and neuroprotective effects of MMP

inhibitors.

Award Recipient Sponsor Title/Description Amount





Frank Giblin National Proteins of Normal and Cataractous $ 373,744

Eye Research Institutes of Lenses. The overall goal of this project

Institute Health is to evaluate the role of oxidative

stress in the development of human

senile cataract. The hypothesis that a

breakdown in antioxidant defense

systems in the lens can lead to

increased levels of prooxidants,

irreversible modification of lens

proteins, and eventual loss of lens

transparency will be tested. Emphasis

will be placed on studying the

mechanism of formation of nuclear

cataract, a major cause of loss of lens

transparency in the aging human.









Frank Giblin National Protection Against UV and X-ray $ 50,000

Eye Research Aeronautics and Cataracts, Using Dynamic Light

Institute Space Scattering as Marker. Researchers

Administration will be collaborating with NASA

scientist, Dr. Rafat Ansari, who has

developed a dynamic light scattering

method for detection of cataracts. The

aims of this research are to use in vivo

dynamic light scattering to investigate

early aggregation of lens crystallins in

experimental animal models for X-ray

and UV induced cataracts, and to test

agents to prevent the X-ray and UV

induced effects on the lenses of the

experimental animals.

Award Recipient Sponsor Title/Description Amount





Andrew Goldberg National Peripherin/RDS in Photoreceptor $ 21,675

Eye Research Institutes of Renewal and Disease. Inherited

Institute Health defects in the rds gene product,

peripherin/rds, cause a variety of retinal

degenerations in humans. However,

neither the normal molecular function of

this protein nor its role in disease is well

understood. This project is based on

the hypothesis that pathogenic

mutations can affect particular

perpherin/rds domains and thereby

selectively inhibit photoreceptor disk

morphogenesis, disk stacking, or disk

shedding to contribute to a broad

heterogeneity of retinal disease. This

award provides additional funding for

this project.









Lynn United States GEAR-UP. The goal of this project is $ 330,926

Hockenberger Department of the transformation of a middle school

Learning Education educational environment to a student

Resources success model through the efforts of a

Jane Goodman city-wide collaborative resulting in

Counseling higher levels of student achievement,

Rhonda Blackwell- high school graduation, and college

Flanagan enrollment.

Curriculum,

Instruction, and

Leadership

Award Recipient Sponsor Title/Description Amount





Bo-Nan Jiang National Collaborative Research: The Least- $ 120,000

Mathematics and Science Squares Meshfree Particle Finite

Statistics Foundation Element Method. The objective of this

project is to enable numerical

simulations beyond current capabilities

in many important applications of

national interest. This project will also

serve as an important component of

the new PhD program on

computational mathematics at Oakland

University. The new method will be

immediately applied to emergent

problems in NASA and the automotive

industry.









Qingchong Liu National Investigations on CDMA Systems $ 67,477

School of Science Using Multiple Level Sequences and

Engineering and Foundation Partitioned Reduced Complexity

Computer Science Multi-User Detection Receivers.

CDMA systems have achieved great

commercial success in wireless

communications since first deployed in

1994. This project will address the

problem of demodulation in the

presence of multiple access

interference that remains as a

significant bottleneck for CDMA

systems. This research will be

conducted as a collaborative effort

between researchers at Oakland

University and Ohio University.

Award Recipient Sponsor Title/Description Amount





Lunjin Lu National INT: Backward Analysis of Logic $ 40,000

School of Science Programs. Backward analysis

Engineering and Foundation propagates information in the reverse

Computer Science direction of program execution and is

useful in deriving conditions under

which the execution of the program

meets certain demands. Though

backward analysis has been a subject

of intense research in functional

programming, it has rarely been applied

in logical programming. This research

project aims to research theoretical and

practical issues in backward logic

program analyis by 1) developing a

framework for designing, implementing,

and evaluating backward analyses, and

2) developing some specific backward

analyses that provide useful

information in program debugging,

compilation, and specialization.









Zissimos General Motors Optimal Design of an Automatic $ 25,000

Mourelatos Corporation Transmission Park System for

School of Engagement Speed Performance

Engineering and Considering Uncertainty. The

Computer Science primary function of an automatic

transmission park system is to prevent

the motion of a vehicle when it is

activated. This project will address the

following issues: 1) assessment of

reliability and sensitivity to component

variation, 2) percent contribution of

component variation for a given park

system design, and 3) calculation of a

park system design for optimal

engagement speed performance

considering component variations.

Award Recipient Sponsor Title/Description Amount





Zissimos General Motors Optimization of an Engine Head $ 23,000

Mourelatos Corporation Gasket Thermo-Structural

School of Performance Considering

Engineering and Uncertainty. The objective of this

Computer Science project is to demonstrate how

uncertainty can be considered in

optimizing the thermo-structural

performance of an engine head gasket.









Zissimos University of Reliability and Robustness in $ 50,000

Mourelatos Michigan Optimal Design. In this project,

School of Automotive researchers will use and extend

Engineering and Research existing reliability-based design

Computer Science Center optimization (RBDO) methods in

optimal design. Computationally

efficient "single-loop" RBDO

formulations will be developed in which

reliability terms are replaced by

deterministic functions. The RBDO

formulations will be also extended for

optimal robust design by including the

standard deviations as design

variables. Finally, a multidisciplinary

case study will be performed by

optimizing an I.C. engine piston

ring/liner system under uncertainty.









Michael Polis Altair Michigan Economic Development $ 3,259

School of Engineering, Corporation Economic Development

Engineering and Inc. Job Training - Altair Engineering,

Computer Science Inc. This funding will be used to train

employees of Altair Engineering, Inc.

This represents the company's share of

funding.

Award Recipient Sponsor Title/Description Amount





Alan Ruby National Age Related Eye Disease Study. This $ 301,883

Eye Research Institutes of project is a follow-up study to

Institute Health adequately assess the safety and

efficacy of study therapy and

understand better the clinical course of

macular degeneration and cataract.









Edzko Smid Collins & Technical Support for the Collins $ 42,500

School of Aikman and Aikman ACE. On-site support for

Engineering and Products Co. the Advanced Cockpit Enabler (ACE)

Computer Science Simulation Laboratory including

graphics simulation environment, data

acquisition, user manuals, architecture

design and support, Matlab/Simulink

modeling, and virtual vehicle system

simulation.









Uma National High Pressure Studies in Carbon $ 63,092

Venkateswaran Science Nanotubes. Researchers will conduct

Department of Foundation high pressure optical and electrical

Physics studies on carbon nanotubes to

elucidate fundamental physical

properties. This funding is for year

three of this project.





Douglas Wendell National Attenuation of Estrogen-Induced $ 144,500

Biological Sciences Institutes of Cell Proliferation. The goal of this

Health project is to determine the role of

Edpm3 in regulation of cell proliferation.

Specific aims are 1) to develop an in

vitro system, 2) to determine the effect

of Edpm3 on paracrine communication,

and 3) to identify gene products whose

expression is affected by Edpm3.

Award Recipient Sponsor Title/Description Amount





Lianxiang Yang Automated Software Development of 3D- $ 30,000

School of Precision, Inc. Contour Measurement Based on

Engineering and DMD Technique. The scope of this

Computer Science project includes the following: 1)

automatic recording of three or four

images, 2) create a phase map

according to the registered images, 3)

smoothing such a phase map by

developing a suitable filter algorithm,

4) demodulating the phase map to get

a continuous distribution, 5) evaluating

the demodulated image to get 3D-

contour, 6) displaying the result in a

manner of 3D and 2D, 7) displaying the

results of a large part in a manner of

3D and 2D, and 8) documentation of a

user handbook.







Lianxiang Yang Automated Proposal on 6D Laser Tracker $ 38,000

School of Precision, Inc. Modeling. This project will focus on 6D

Engineering and tracker modeling. It will include the

Computer Science following work: 1) algorithm for pitch,

yaw, and roll measurement, 2)

determination of encoder offset angle,

3) calibration of target encoder and

electronic level, 4) determination of

initial position of 6D target center, 5)

programming and simulation of 6D

measurement, 6) algorithm for 6D

measurement in object reference

frame, and 7) error analysis of 6D

measurement.

Award Recipient Sponsor Title/Description Amount





Jill Zeilstra-Ryalls National Regulation of 5-Aminolevulinic Acid $ 176,872

Biological Sciences Science Biosynthesis in Rhodabacter

Foundation Sphaeriodes 2.4.1. The goal of this

project is to develop an understanding

of how hemA and hemT, in response to

environmental conditions, can meet the

changing demands for 5-aminolevulinic

acid (ALA) in the model organism

Rhodobacter sphaeroides.

Researchers will examine the

regulation of expression of each of

these genes.









Total $ 2,728,394



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