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MULTIPLE SCLEROSIS (MS)

“Join The Movement”









By: Jessica L. Flemming

CAN YOU ANSWER THIS?



 If you have MS, will you eventually be

disabled and/or need a wheelchair?



 Is MS contagious or inherited?



 Is MS fatal?

What is Multiple Sclerosis?



 Inflammatory disease of the CNS that damages the

myelin sheath (or the insulating material, that surrounds

the nerve fibers in the brain, spinal cord & optic nerves).



 Myelin is lost in multiple areas, leaving plaques or scars

called scleroses (thus the name Multiple Sclerosis).



 Characterized by attacks which may be associated with

plaques that prevent conduction of nerve impulses in the

CNS.

MS & Myelin



 In MS, myelin is broken down, causing disruptions in the

signals sent to & from the brain. Injury to the nerves may

alter virtually any sensory or motor (muscular) function.

What Goes Wrong in MS?



 When Myelin is damaged, dense scar-like tissue

forms around nerve fibers throughout the brain &

spinal cord.

 These scars or lesions can slow down or completely

prevent the transmission of signals between nerve

cells.

 Messages from the brain & spinal cord cannot reach

other parts of the body and thus symptoms occur.

What Causes Multiple Sclerosis?



 The exact cause of MS is unknown.



 Most researchers believe that it is due to a

combination of genetic, immunological &

environmental factors.



 MS is believed to be an autoimmune

process.

Symptoms are Different for Everyone

with MS.



 Mild Symptoms  More Severe

Fatigue, weakness, Symptoms

balance problems, Problems with information

dizziness, bladder processing, loss of

control, numbness, sensation, decreased

vision loss, tremors, concentration, attention

muscle spasm, speech deficits, memory loss,

impediment & sexual dysfunction &

depression. physical disability.

Criteria For Diagnosis?



 A neurologist is the medical specialist that is trained to

evaluate the symptoms of MS.



 Tests such as magnetic resonance imaging (MRI),

cerebrospinal fluid tests, and electro-encephalogram (EEG)

aid in accurate diagnosis.



 Definite MS= history of more than one attack, at least one

month apart, and evidence that myelin has been damaged in

more than one area of the brain and/or spinal cord.



 “Probable MS”= do not meet above criteria, but still have

symptoms.

Magnetic Resonance Imaging (MRI)



 Brain with MS lesions.

Who Gets MS?



 Twice as many women as men



 2.5 million Worldwide- 400,000 Americans (200/wk)



 Generally diagnosed between the ages 20 & 40.



 More common among Caucasians, especially those

of northern European ancestry.

Classifying MS (4 general categories)



 Periods of active MS symptoms are called attacks,

exacerbations, or relapses. These can be followed by

quiet periods called remissions.

 Relapsing-Remitting MS

 Primary Progressive MS

 Secondary Progressive MS

 Progressing Relapsing MS

Can MS be Treated?



 Yes. Today, there are 6 federally approved

medications that treat MS.



 Avonex, Betaseron, Rebif & Copaxone have been

shown to be effective for modifying the natural

course of Relapsing MS.

 Tysabri (monotherapy)



 Novantrone is effective in slowing down MS that is

rapidly worsening or becoming progressive.

Some Statistics of MS



 Most people with MS have a normal life expectancy.

 2/3 of those with MS are still walking 20 years after

developing the disease.

 40% of persons diagnosed with MS experience little

or no disruptions of normal activities.

 75% of individuals with MS will not use a wheelchair.

 MS is not contagious and is not considered fatal.

 There is not a CURE for MS as of today, but we are

close.

“IN OUR THOUGHTS AND PRAYERS”









RYAN D. HYDE

PROUDLY SERVING THE USA IN AFGHANISTAN 2007



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