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Ethan Frome

VIEWS: 27 PAGES: 8

									     ALAA EL-DEEN BAKRY YASSIN, PHD
           CURRICULUM VITAE
                                      2007
TITLE:
   Associate Professor, Department of Pharmaceutics, King Saud
   University, Riyadh, Saudi Arab Kingdom.

ADDRESS:
  Business:
  Faculty of Pharmacy, King Saud University, Department of
  Pharmaceutics, P.O.Box 2457, Riyadh 11451, Saudi Arab
  Kingdom.
  Telephone: (9661)-4677499
  Fax: (9661)-4676295
  E-Mail: abyassin2002@yahoo.com
  Website: http://faculty.ksu.edu.sa/dralaayassin/default.aspx

   Home:
   Olaya Main Street, Bin-Saleem Center, Olaya, Riyadh 11413,
   Saudi Arab Kingdom.
   Telephone: (9661)-293-3590
   Mobile : 966-509426323

PERSONAL INFORMATION
  Nationality: Egyptian
  Birth Date: May 28, 1961
  Marital Status: Married and having one boy and two girls.
  Social Security Number (USA): 389-11-0003

EDUCATION
  B.S., Pharmacy and Pharmaceutical Chemistry, Cairo
  University, Cairo, Egypt (1983).
  M.S., Pharmaceutics, Al-Azhar University, Cairo, Egypt (1990).
  Thesis Title: "Preformulation, formulation, and bioavailability of
  three indomethacin tablet forms"
  Ph.D., Pharmaceutics, University of Wisconsin, Madison,
  Wisconsin, USA (1996).1
……………………………………………………………………………………………………………..
1. I was a channel exchange student. My course work and research was conducted at the
   University of Wisconsin but my degree was granted from Al-Azhar University, Cairo,
   Egypt.
    Thesis Title: "Study of The Influence of Effervescence
    (Carbonation) on the mechanism of intestinal absorption of
    different drug models"

AREAS OF EXPERTISE IN DRUG DEVELOPMENT

     Drug targeting to the colon
     Controlled drug delivery systems. In particular, gastro-
      retentive (bioadhesive and floating) dosage forms.
     Design and preparation of oral solid (tablets and capsules)
      dosage forms.
     Evaluation of formulations for all USP quality control tests,
      stability (shelf and accelerated), pharmacokinetics and
      bioavailability in human and dogs.
     Analysis of drugs in pure forms, formulations and biological
      matrices.

WORK HISTORY
  March 2004- present : Associate Professor, Pharmaceutics
   Department, College of Pharmacy, King Saud University,
   Riyadh, Saudi Arabia.

     Nov. 1999 –March 2004: Assistant Professor, Pharmaceutics
      Department, College of Pharmacy, King Saud University,
      Riyadh, Saudi Arabia.

     Sept. 1996 - Nov. 1999: Assistant professor, Pharmaceutics
        Dept., Faculty of pharmacy, Al-Azhar University,
        Cairo, Egypt.

     Sept. 1998 - Nov. 1999: Scientific Consultant, T3A Pharma
      Group (a new generic Pharmaceutical company in Egypt),
      Cairo, Egypt.

     Nov. 1994 - Sept. 1996: Research Assistant, Dept. of
      Pharmaceutics, Faculty of Pharmacy, Al-Azhar University,
      Cairo, Egypt.

     Oct. 1992 - Nov. 1994: Exchange Ph.D. Student, School of
      Pharmacy, University of Wisconsin, Madison, Wisconsin,
      USA.


C.V. Dr. Alaa El-deen B. Yassin                                    2
     June 1990 - Oct. 1992: Associate Lecturer, Dept. of
      Pharmaceutics, Faculty of Pharmacy, Al-Azhar University,
      Cairo, Egypt.

     Jan. 1985 - June 1990: Instructor, Dept. of Pharmaceutics,
      Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.

     Oct. 1983 - Jan. 1985: Pharmacist, Egyptian Army.

COURSE WORK

    1. Introduction to Computer Science, Physical Chemistry,
       Biostatistics, Pharmaceutical Instrumental Analysis (Al-Azhar
       University, Cairo, Egypt), Academic Year 1986.

    2. Preformulation of Solid dosage Forms and Advanced
       Pharmaceutical Formulation (Al-Azhar University, Cairo,
       Egypt), Academic Year 1987.

    3. Biopharmaceutics       and    Pharmacokinetics     (Al-Azhar
       University, Cairo, Egypt), Academic Year 1988.

    4. Development of Dosage Forms, Pharmaceutical Technology
       (Al-Azhar University, Cairo, Egypt), Academic Year 1988.

    5. Interfacial Phenomena, (University of Wisconsin, Madison,
       Academic Year 1993.

    6. Equilibria in Pharmaceutics, (University of Wisconsin,
       Madison, Academic Year 1993.

    7. Drug Targeting, (University      of   Wisconsin,   Madison,
       Academic Year 1993.

    8. Controlled Release and Drug Delivery, (University of
       Wisconsin, Madison, Academic Year 1994.

PROFESSIONAL ORGANIZATIONS MEMBERSHIP

     The American Association of Pharmaceutical Scientists
      (AAPS).
     The Egyptian Pharmaceutical Society.

C.V. Dr. Alaa El-deen B. Yassin                                    3
     The Arab Pharmacists Union.
     The Saudi Pharmaceutical Society.
     The Arab American Association             of   Pharmaceutical
      Scientists.
     Syndicate of Pharmacists of Egypt.


SPECIAL SKILLS

    • Animal Experimentation with various In-vitro & In-situ
      Techniques e.g. Cannulated Dog Model and Rat Perfusion
      Technique.

    • Formulation of Various Dosage Forms specially Tableting
      (Direct Compression and Wet granulation) and pan coating.

    • Bioavailability, Bioequivalence, and Pharmacokinetic Studies
      in Animals and Humans.

    • Various Analytical techniques including HPLC, Spectrometry,
      Gas Chromatography, and Differential Scanning Calorimetery
      (DSC).

    • Prepare, develop and review protocols and reports in
      compliance with GLP and cGMP.

Supervision

    1. Co-advisor of the master thesis of Dalia Abd-ElRahman Attia
       (1998-2002). The title of the thesis: Design and evaluation of
       a colonic drug delivery system.

    2. Principal advisor of the master thesis of Fayza Ahmad
       Elkhaled (1999-2003). The title of the thesis: Bioadhesive and
       floating formulations as sustained release dosage forms for
       verapamil hydrochloride.

Academic Activities

    1. Academic coordinator in Dept. of Pharmaceutics, College of
       Pharmacy, KSU (2005-present).

    2. Chair of the Master Program Developing Committee (2006).

C.V. Dr. Alaa El-deen B. Yassin                                     4
    3. Member of the Center for Excellence in Biotechnology
       Research in King Saud University (College of Pharmacy
       group).

    4. Reviewer for :
            -Saudi Pharmaceutical Journal (SPJ).
            -European    Journal    of     Pharmaceutics and
            Biopharmaceutics (EJPB).
            -King Abdulazeez City for Science and Technology
            (KACST).


CURRENT RESEARCH GRANTS

      Principal Investigator (PI) on the following competitive grants:

        1. Design and optimization of nanocapsule oral delivery
           system(s) for poorly absorbed drug, Research center of
           Pharmacy, KSU No. C.P.R.C. with total budget 35,000
           SR.

        2.The development of new drug delivery system for
           diagnosis and treatment of colon cancer, King Abdulaziz
           city for science and technology No. ‫ 32-52-أ ت‬with total
           budget 880,286 SR.



LIST OF PUBLICATIONS

    1. “Indomethacin    Direct    Compression    Excipients    :
       Preformulation Stability Screening Using Differential
       Scanning Calorimeter” , Hamed H. El-Shattawy, Alaa El-din
       A. Kassem, Ahmad M. Sami, and Alaa El-din B. Yassin,
       Presented during The Pan Pacific VI Conference, May, 19-
       23, 1991, Honolulu,Hawaii,USA.

    2. “Bioavailability of Directly Compressed Indomethacin,
       Indomethacin Sodium, and Indomethacin Meglumin
       Tablets”, Hamed H. El-Shattawy, Alaa El-din A. Kassem,
       Sanaa Omar, Ahmad M. Sami, and Alaa El-din B. Yassin,
       Drug Development and Industrial Pharmacy, 20(3), 367-373,


C.V. Dr. Alaa El-deen B. Yassin                                          5
         1994 [Presented at American Association of Pharmaceutical
         Scientist (AAPS) 6th National Meeting and Exposition,
         Washington D.C., USA, Nov.19-21, 1991].

    3. “Preparation and Evaluation of Directly Compressed
       Indomethacin,   Indomethacin   Sodium,     Indomethacin
       Meglumin Tablets”, Hamed H. El-Shattawy, Alaa El-din A.
       Kassem, Sanaa Omar, Ahmad M. Sami, and Alaa El-din B.
       Yassin, Drug Development and Industrial Pharmacy, 20(5),
       901-909, 1994.

    4. “The influence of in-vivo carbonation on GI physiological
       processes and drug permeability : Bioadhesion : State-of-
       the-art and perspectives”, Jonathan D. Eichman, Alaa El-
       din B. Yassin, and Joseph R. Robinson, European journal
       of pharmaceutics and biopharmaceutics , vol. 44, no 1, 33-
       38, 1997. [ Presented at Symposium Proceedings on
       “Recent Advances in Bioadhesion”, Sponsored by Pharma
       Peptides, Geneva, Switzerland, October 2-4, 1996].

    5. “Study of The Influence of Effervescence (Carbonation) on
       Gastric Emptying Rate, pH, and Mucus Content”, Alaa El-
       din B. Yassin, Hamed H. El-Shattawy, Alaa El-din A.
       Kassem, Joseph R. Robinson, Egypt. J. Biotechnol., 10,
       420-431, July 2001.

    6. “Mechanistic Studies on Enhanced Intestinal Absorption of
       Carbonation Using Tetracycline and Mannitol as Model
       Drugs”, Alaa El-din B. Yassin, Hamed H. El-Shattawy, Alaa
       El-din A. Kassem, Joseph R. Robinson, Egypt. J.
       Biotechnol., 10, 446-454, July 2001.

    7. “Colonic Targeting of Metronidazole : Preparation and In-
       Vitro Evaluation of Three Delivery Systems”, Alaa El-din B.
       Yassin, Dallia AbdulRahman, Alaa El-din A. Kassem, Az. J.
       Pharm. Sci., 28, 212-220, 2001.

    8. “Preparation and In-Vitro Evaluation of a New Gastro-
       retentive Extended-Release Verapamil HCl Tablets Using
       Some Bioadhesive Polymers”, Seham A. Elkheshen, Alaa
       Eldeen B. Yassin, Fayza A. Alkhaled, Bulletin of Faculty of
       Pharmacy Cairo university, 41, 1, 2003.



C.V. Dr. Alaa El-deen B. Yassin                                  6
    9. “Per-oral Extended-Release Bioadhesive Tablet Formulation
       of Verapamil HCl”, Seham A. Elkheshen, Alaa Eldeen B.
       Yassin,    Fayza    A.   Alkhaled,   Bollettino  Chimico
       Farmaceutico, 142, 5, 226-231, 2003.

    10. “Comparative Bioavailability of Two tablet Formulations of
       Metronidazole in Human Volunteers: An Assessment of
       Colonic Targeting”, Alaa El-din B. Yassin, Dallia
       AbdulRahman, Alaa El-din A. Kassem, Egypt. J. Biomed.
       Sci., 12, July, 40-48, 2003.

    11. Colonic Targetting Using Chitosan and Chitosan/Pectin
        Mixtures: An In-Vitro Evaluation., Alaa El-din B. Yassin,
        Egypt. J. Biomed. Sci., 12, July, 174-183, 2003.

    12. “Intra-gastric Performance and Bioavailability Study of a
       New Per-oral Bioadhesive Verapamil HCl Matrix Tablet in
       Dogs”, Alaa Eldeen B. Yassin, Fayza A. Alkhaled, Saleh
       Al-Suwayeh, Seham A. Elkheshen, Bollettino Chimico
       Farmaceutico, 142, 7, 285-289, 2003.

    13. “The Impact of Aging on the In Vito Release Characteristics
        of Some Colonic Delivery Systems” Alaa Eldeen B. Yassin,
        Scientific Journal of Al-Azhar Medical Faculty (girls), 25 (1),
        141-147, 2004.

    14. "In vitro and in vivo Evaluation of Floating Controlled
       Release Dosage Forms of Verapamil Hydrochloride" Seham
       A. Elkheshen, Alaa Eldeen B. Yassin, Saleh A. Al-
       Suwayeh, Fayza A. Alkhaled, Pharm. Ind. 66, No. 11, 1364-
       1372, 2004.

    15. "In vitro Characterization of Carbamazepine-Loaded
        Precifac Lipospheres" Nahla S. Barakat and Alaa Eldeen B.
        Yassin. Drug Delivery, 13(2), 95-104, 2006.

    16. "Chitosan Beads as a new gastroretentive system of
        Verapamil", A.B. Yassin, I.A. Alsarra, A.M. Al-Mohizea,
        Scientia Pharmaceutica, 74, 175-188.2006.

    17. "Enhanced Bioavailability of Flurbiprofen in Human
        Volunteers Using Gelucire 44/14 and Laprasol as Semi-



C.V. Dr. Alaa El-deen B. Yassin                                       7
         Solid Dispersions", Soliman MS, Abd-allah FI, Yassin AB,
         Egypt. J. Biomed. Sci., 16, , 141-148, 2007.

    18. “Improvement of the oral bioavailability of spironolactone
        using spray-drying technique”. Mahmoud Albadry, Alaa
        Eldeen B. Yassin, Fars Alenazy, Nahla Barakat. In
        preparation.


    19. HPLC-Stability indicating assay for 5-flurouracil in different
        biological fluids. Fars Alanazy, Alaa Eldeen B. Yassin,
        Abdullah AlMohizea, Ibrahim Alsarra, Hammam Abdulmoez,
        and Mahmoud AlBadry. In preparation.

    20. “Preparation and in situ evaluation of a colonic drug delivery
        system for 5-FU using compression coating technique. Alaa
        Eldeen B. Yassin, Abdullah AlMohizea, Fars Alanazy,
        Ibrahim Alsarra. In preparation.

    21. Optimization of a new gastroretentive drug delivery utilizing
        a simple direct compression technique. Alaa Eldeen B.
        Yassin. In preparation.




C.V. Dr. Alaa El-deen B. Yassin                                      8

								
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