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Category Term PValue Count Pop Hits _REPRESENTATION BP development ...

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Category Term PValue Count Hits %REPRESENTATION

BP development 0.0001 118 1865 6.33

BP cell adhesion 0.0002 53 685 7.74

BP response to stress 0.0003 76 1114 6.82

MF protein binding 0.0007 236 4746 4.97

BP cellular carbohydrate metabolism 0.0009 31 360 8.61

BP cell proliferation 0.0010 42 545 7.71

BP carbohydrate metabolism 0.0010 41 529 7.75

BIOCARTA h_Ccr5Pathway:Pertussis toxin-insensitive CCR5 Signaling in Macrophage 0.0014 7 25 28.00

BP hemostasis 0.0015 13 98 13.27

MF ion binding 0.0020 193 3854 5.01

MF metal ion binding 0.0020 193 3854 5.01

CC membrane 0.0022 308 5797 5.31

BP regulation of body fluids 0.0037 13 109 11.93

MF obsolete molecular function 0.0044 24 306 7.84

MF cadmium ion binding 0.0049 4 9 44.44

MF heavy metal binding 0.0049 4 9 44.44

BP response to abiotic stimulus 0.0051 34 456 7.46

MF heparin binding 0.0057 10 80 12.50

CC cell fraction 0.0058 54 796 6.78

MF enzyme regulator activity 0.0060 44 699 6.29

BP wound healing 0.0062 12 102 11.76

BP blood coagulation 0.0084 11 92 11.96

BP establishment of localization 0.0090 165 3077 5.36

BP coagulation 0.0097 11 94 11.70

h_cardiacegfPathway:Role of EGF Receptor Transactivation by GPCRs in Cardiac

BIOCARTA Hypertrophy 0.0100 5 17 29.41

BP morphogenesis 0.0100 41 605 6.78

MF binding 0.0101 531 12108 4.39

BP localization 0.0105 165 3093 5.33

MF cation binding 0.0113 175 3598 4.86

BP response to chemical stimulus 0.0126 29 396 7.32

MF calcium ion binding 0.0130 54 938 5.76

BP response to unfolded protein 0.0132 9 70 12.86

BP response to protein stimulus 0.0132 9 70 12.86

MF hormone activity 0.0154 12 126 9.52

MF structural constituent of cytoskeleton 0.0157 10 94 10.64

KEGG HSA00010:GLYCOLYSIS / GLUCONEOGENESIS 0.0179 9 63 14.29

BP endocytosis 0.0182 14 150 9.33

CC plasma membrane 0.0183 102 1769 5.77

MF enzyme inhibitor activity 0.0191 20 273 7.33

BP regulation of cell proliferation 0.0192 23 303 7.59

CC extracellular region 0.0194 78 1306 5.97

BP cell organization and biogenesis 0.0224 87 1543 5.64

BP negative regulation of cell proliferation 0.0232 14 155 9.03

BIOCARTA h_AcetaminophenPathway:Mechanism of Acetaminophen Activity and Toxicity 0.0246 3 5 60.00

BP response to wounding 0.0249 28 401 6.98

CC extracellular matrix (sensu Metazoa) 0.0255 24 318 7.55

CC intrinsic to plasma membrane 0.0257 74 1247 5.93

BP transport 0.0265 149 2837 5.25

BP regulation of S phase of mitotic cell cycle 0.0270 3 6 50.00

KEGG HSA00620:PYRUVATE METABOLISM 0.0280 7 44 15.91

MF glycosaminoglycan binding 0.0283 10 104 9.62

BP mitotic cell cycle 0.0286 17 210 8.10

CC caveola 0.0289 3 6 50.00

CC integral to plasma membrane 0.0300 73 1239 5.89

CC extracellular matrix 0.0316 24 325 7.38

BP response to external stimulus 0.0327 34 523 6.50

BP glycosaminoglycan metabolism 0.0329 6 40 15.00

BP cell-cell signaling 0.0343 35 544 6.43

MF polysaccharide binding 0.0349 10 108 9.26

BP epidermis development 0.0355 9 84 10.71

BP glycogen metabolism 0.0356 5 28 17.86

BP behavior 0.0361 16 199 8.04

BP aminoglycan metabolism 0.0361 6 41 14.63

CC membrane fraction 0.0374 39 603 6.47

BP humoral immune response 0.0377 14 166 8.43

KEGG HSA04080:NEUROACTIVE LIGAND-RECEPTOR INTERACTION 0.0393 24 294 8.16

BP response to other organism 0.0393 38 607 6.26

BP glucan metabolism 0.0398 5 29 17.24

MF transporter activity 0.0404 88 1751 5.03

MF arylsulfatase activity 0.0405 3 8 37.50

BP M phase of mitotic cell cycle 0.0442 13 153 8.50

CC cytoplasmic membrane-bound vesicle 0.0442 14 164 8.54

MF sequence-specific DNA binding 0.0446 28 461 6.07

CC intrinsic to membrane 0.0454 229 4437 5.16

CC cytoplasmic vesicle 0.0461 14 165 8.48

CC clathrin-coated vesicle 0.0468 10 101 9.90

MF copper ion binding 0.0474 8 80 10.00

BP S phase of mitotic cell cycle 0.0475 3 8 37.50

BP S phase 0.0475 3 8 37.50

BIOCARTA h_tsp1Pathway:TSP-1 Induced Apoptosis in Microvascular Endothelial Cell 0.0482 3 7 42.86

CC coated vesicle 0.0498 11 118 9.32

CC membrane-bound vesicle 0.0499 14 167 8.38

CC integral to membrane 0.0505 228 4428 5.15

CC vesicle 0.0519 14 168 8.33

BP cell growth 0.0541 13 158 8.23

BP regulation of cell size 0.0541 13 158 8.23

BP regulation of progression through cell cycle 0.0555 30 472 6.36

BP regulation of cell cycle 0.0579 30 473 6.34

MF pattern binding 0.0584 10 119 8.40

BP regulation of pH 0.0589 4 20 20.00

BP vacuolar transport 0.0593 3 9 33.33

BP cellular physiological process 0.0593 517 11042 4.68

MF growth factor activity 0.0598 14 194 7.22

MF receptor binding 0.0599 39 707 5.52

BP response to pest, pathogen or parasite 0.0600 35 571 6.13

MF solute:hydrogen antiporter activity 0.0605 4 22 18.18

MF solute:cation antiporter activity 0.0605 4 22 18.18

CC cell surface 0.0609 8 75 10.67

MF acid phosphatase activity 0.0617 3 10 30.00

BP ectoderm development 0.0617 9 94 9.57

KEGG HSA05110:CHOLERA - INFECTION 0.0653 6 41 14.63

BP nervous system development 0.0663 30 479 6.26

BP ion transport 0.0663 47 813 5.78

MF magnesium ion binding 0.0668 19 296 6.42

MF kinase binding 0.0691 7 70 10.00

BP protein targeting 0.0703 13 165 7.88

BP fatty acid metabolism 0.0703 13 165 7.88

BP cell maturation 0.0713 5 35 14.29

BP system development 0.0715 30 483 6.21

BP prostanoid biosynthesis 0.0719 3 10 30.00

BP prostaglandin biosynthesis 0.0719 3 10 30.00

MF antiporter activity 0.0763 6 55 10.91

BP locomotion 0.0768 17 240 7.08

BP localization of cell 0.0768 17 240 7.08

BP cell motility 0.0768 17 240 7.08

CC synapse 0.0773 11 128 8.59

MF alkali metal ion binding 0.0779 13 183 7.10

BP cellular morphogenesis 0.0789 19 278 6.83

BP mitosis 0.0799 12 151 7.95

MF prostaglandin-endoperoxide synthase activity 0.0810 2 2 100.00

BP sulfur metabolism 0.0811 7 67 10.45

MF cyclophilin-type peptidyl-prolyl cis-trans isomerase activity 0.0826 4 25 16.00

MF cyclophilin 0.0826 4 25 16.00

MF FK506-sensitive peptidyl-prolyl cis-trans isomerase 0.0826 4 25 16.00

BP cellular polysaccharide metabolism 0.0842 6 52 11.54

BP cell differentiation 0.0855 31 512 6.05

MF peroxidase activity 0.0882 5 41 12.20

MF oxidoreductase activity, acting on peroxide as acceptor 0.0882 5 41 12.20

BP vacuolar acidification 0.0882 2 2 100.00

CC synaptic vesicle 0.0890 6 51 11.76

BP regulation of cell adhesion 0.0906 5 38 13.16

MF solute:solute antiporter activity 0.0906 4 26 15.38

CC aminoacyl-tRNA synthetase multienzyme complex 0.0914 2 2 100.00

CC hydrogen-transporting ATPase V1 domain 0.0914 2 2 100.00

BP phagocytosis 0.0917 4 24 16.67

BP icosanoid biosynthesis 0.0917 4 24 16.67

BP actin filament organization 0.0917 4 24 16.67

BP tissue development 0.0919 14 191 7.33

MF enzyme binding 0.0935 13 189 6.88

MF guanyl-nucleotide exchange factor activity 0.0936 10 131 7.63

BIOCARTA h_eicosanoidPathway:Eicosanoid Metabolism 0.0940 4 21 19.05

BP fatty acid biosynthesis 0.0954 6 54 11.11

MF protein kinase binding 0.0963 6 59 10.17

KEGG HSA00052:GALACTOSE METABOLISM 0.0968 5 33 15.15

BP cellular process 0.0978 607 13187 4.60

BP zinc ion transport 0.0995 3 12 25.00

BP heparan sulfate proteoglycan metabolism 0.0995 3 12 25.00



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