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									  „ZUSAMMENARBEIT – Gesundheit“ und
    „Forschung zugunsten kleiner und
      mittlerer Unternehmen (KMUs)“
       im 7. EU-Rahmenprogramm

                    Ylva Huber

  Bereich Europäische und Internationale Programme
FFG – Österreichische Forschungsförderungsgesellschaft
Inhalt


• Das 7. Rahmenprogramm im Überblick

• Themen der ersten Ausschreibungen zu „Gesundheit“

• Forschung zugunsten kleiner und mittlerer Unternehmen
  (KMU)
Inhalt


• Das 7. Rahmenprogramm im Überblick

• Themen der ersten Ausschreibungen zu „Gesundheit“

• Forschung zugunsten kleiner und mittlerer Unternehmen
  (KMU)
Instrumente im 7. RP

7. EU-Rahmenprogramm                      6. EU-Rahmenprogramm
Verbundprojekte („Collaborative           Integrierte Projekte (IP)
Projects)                                 Gezielte Forschungsprojekte (STREPs)
Exzellenznetze (NoE)                      Exzellenznetze (NoE)
Koordinierungsmaßnahmen (CA)              Koordinierungsmaßnahmen (CA)
Unterstützungsmaßnahmen (SSA)             Unterstützungsmaßnahmen (SSA)
Unterstützung für Ausbildung und          Unterstützung für Ausbildung und
Karriereentwicklung (Marie-Curie)         Karriereentwicklung (Marie-Curie)
Einzelprojekte im ERC (Programm
Ideas)
KMU spezifische Maßnahmen                 KMU spezifische Maßnahmen
Artikel 169                               Artikel 169
ERA-NET und ERA-NET PLUS                  ERA-NET
Gemeinsame Technologieinitiativen (JTI)
            Die Ausschreibungen sind geöffnet!




                            rp7.ffg.at
25. Februar 2005        Präsentationstitel der FFG   6
Inhalt


• Das 7. Rahmenprogramm im Überblick

• Themen der ersten Ausschreibungen zu „Gesundheit“

• Forschung zugunsten kleiner und mittlerer Unternehmen
  (KMU)
Thema 1- Gesundheit
(6.050 Mio. Euro)

 Ziele:
 Verbesserung der Gesundheit der europäischen Bevölkerung
 Stärkung der europ. Industrie/Firmen
  im Bereich Gesundheit
 Blick auf globale Gesundheitsfragen
  (z.B. Epidemien

 Schwerpunkte:
 Translationale Forschung (Grundlagenforschung  klinische
                            Anwendung)
 Neue Therapien (Entwicklung und Validierung)
 Methoden zur Gesundheitsförderung, Krankheitsprävention
 Diagnostische Instrumente und medizinische Technologien
 Effiziente Gesundheitssysteme
Thema 1: Gesundheit

(6.050 Mio. €)

Einreichfrist 1. Ausschreibung: 19. April 2007
Einreichfrist 2. Ausschreibung: 18. September 2007

         Biotechnology, generic tools and technologies for human
 1                                health



 2                Translating research for human health



 3      Optimising the delivery of health care to European Citizens



 4               Other Actions across the Health Theme
               Biotechnology, generic tools and technologies for human
    1                                  health (1)

High-throughput research

       Unifying human and model organism genetic variation databases
       Temporal and spatial proteomics to study biological processes relevant to
        human health
       Groundbreaking techniques for DNA sequencing and genotyping
        2. Call:
       SME-driven collaborative research projects for developing tools and technologies
        for high-throughput research

Detection, Diagnosis and Monitoring

       Development of a hybrid imaging system
       Novel optical methodologies for detection, diagnosis and monitoring of disease or
        disease-related processes
       Novel targeted imaging probes for early in vivo diagnosis and/or evaluation of
        response to therapy
       In vivo image-guidance for cell therapy
        2. Call :
       Standardisation and improvement of pre-analytical procedures for in vitro
        diagnostics
       High throughput molecular diagnostics in individual patients for genetic
        diseases with heterogeneous clinical presentation
            Biotechnology, generic tools and technologies for human
    1                               health (2)


Predicting suitability, safety and efficacy of therapies

Thema zum Großteil durch Innovative Medicines Initiative (IMI) abgedeckt!

   Novel alternative testing strategies for use in pharmaceutical discovery and
    development
   Bottlenecks in reduction, refinement and replacement of animal testing in
    pharmaceutical discovery and development
   Promotion, development, validation, acceptance and implementation of QSARs
    (quantitative structure-activity relationship) for toxicology
   Alternative testing strategies for the assessment of the toxicological profile of
    nanoparticles used in medical diagnostics
   In silico modelling for ADMET outcomes
              Biotechnology, generic tools and technologies for human
    1                                 health (3)

Innovative therapeutic approaches and interventions

   Development and production of new generation antibodies
   Innovative approaches for the development of vaccines for young children
   Immunotherapy of human food allergies

    2.Call:

   Development of emerging gene therapy tools and technologies for clinical
    application
   Stem cell lines for cell-based therapies.
   Development of stem cell culture conditions.
   Stem cells for kidney regeneration.
   Adding value to EU stem cell therapy research: scientific communication and
    future perspectives.
                    Translating research for human health (1)
    2              2.1. INTEGRATING BIOLOGICAL DATA AND PROCESSES
                   LARGE-SCALE DATA GATHERING, SYSTEMS BIOLOGY


Large-scale data gathering

   Networking biobanking initiatives across Europe: developing standards and
    norms for existing and future human sample biobanks
   Molecular epidemiological studies in existing well characterised European
    (and/or other) population cohorts
   Comparative studies of genetic variation in humans: towards a reference
    population in Europe
   Characterisation and variability of the microbial communities in the Human
    Body
   Structure-function analysis of membrane-transporters and channels for the
    identification of potential drug target sites
   High throughput analysis of lipids and lipid-protein interactions
   Genome-wide association studies in mammalian non-rodent models for the
    identification of genes relevant to human health and disease
                      Translating research for human health (2)
    2               2.1. INTEGRATING BIOLOGICAL DATA AND PROCESSES
                    LARGE-SCALE DATA GATHERING, SYSTEMS BIOLOGY


Systems biology

   A system approach to eukaryotic unicellular organism biology
   Modelling of T-cell activation
   Fundamental approaches to stem cell differentiation
   Developing an integrated in vitro, in vivo and systems biology modelling approach to
    understanding apoptosis in the context of health and disease

2. call:

   Multidisciplinary fundamental genomics and molecular biology approaches to study
    basic biological processes relevant to health and diseases
   Coordination and Support Actions in large-scale data gathering and systems biology
   Traditional Chinese Medicine in post-genomic era. Specific International
    Cooperation Action. Targeted region: China.
                     Translating research for human health (3)
    2          2.2. RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN
                              DEVELOPMENT AND AGEING


Brain and related diseases

   Stroke and mechanisms underlying ischemic brain damage
   Coding in neuronal assemblies
   Neurobiology of anxiety disorders
   Memory loss: underlying mechanisms and therapy
   From basic spinal mechanisms to spinal cord disease and trauma.
   Neuron-glia interactions in health and disease

2. Call:

   Restorative approaches for therapy of neurodegenerative diseases.
   From mood disorders to experimental models.
   Neuronal mechanisms of vision and related diseases.
   Childhood and adolescent mental disorders. Specific International Cooperation
    Action. Target regions: Eastern Europe and Central Asia and Western Balkans.
                      Translating research for human health (4)
    2          2.2. RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN
                               DEVELOPMENT AND AGEING


Human Development and Ageing

   Novel approaches to reconstitute normal immune function at old age.
   Termination of developmental processes and their reactivation in adult life
   Biomarkers of ageing.
   Increasing the participation of elderly in clinical trials.
   Research on human development and/or healthy ageing across the EU
                     Translating research for human health (5)
  2          2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES:
                     TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH


Anti-microbial drug resistance including fungal pathogens

2. Call:
   Novel targets for drugs against Gram negative bacteria.
   Host-pathogen interactions in infections by Streptococcus pneumoniae.
   An integrated platform for development and clinical evaluation of point-of-care
    diagnostic devices for microbial detection, antibiotic susceptibility determination
    and biomarkers
   Molecular epidemiology to control nosocomial and community spreading of highly
    virulent multi-drug resistant strains of bacterial pathogens.
   Health and economic cost of antimicrobial resistance.
   Conference on genetic and biochemical tools for postgenomic physiological analysis
    of Staphylococcus, in particular MRSA.
                           Translating research for human health (6)
    2              2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES:
                           TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH


HIV, AIDS, malaria and tuberculosis

       HIV/AIDS Drug Discovery and Preclinical Development
       Highly innovative approaches for research into host-pathogen interaction in tuberculosis
       Development of fast tests for the diagnosis of Multi-Drug-Resistant strains of HIV, malaria and
        tuberculosis and of latent tuberculosis infection (LTBI).
       Addressing knowledge gaps in pregnancy malaria.
       New HIV Vaccines inducing broadly-reactive neutralising antibodies.

       2. Call:

       Network on HIV and anti-HIV drug resistance
       HIV and Hepatitis co-infection
       Blocking the transmission of malaria: the mosquito vector target.
       European network for study and clinical management of TB drug resistance.
       Support platform for the development of PRD vaccines
       Highly innovative research in HIV/AIDS, malaria and tuberculosis between Indian and European
        partners. (SICA, Targeted Region: India)
       Coordination of European research activities with global initiatives, including Public-Private-
        Partnerships (SICA; Targeted Regions: ICPC).
       Next generation of researchers for HIV/AIDS, malaria, tuberculosis and neglected infectious
        diseases (SICA; Targeted Regions: ICPC).
                         Translating research for human health (7)
    2           2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES:
                        TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH


Potentially new and re-emerging epidemics

   Development of broadly protective influenza vaccine candidates.
   Identifying immunological mechanisms of protection for influenza vaccines
   Standardisation of immunological assays including surrogate markers for evaluation of new
    influenza vaccines in clinical trials
   Innovative point-of-care diagnostic tests for influenza.
   Development of additional treatment strategies for patients suffering from highly pathogenic
    influenza.
   Development of pandemic influenza containment and mitigation strategies.
   Supporting highly innovative inter-disciplinary research on influenza.
   Influenza research in collaboration with Asian partners. (SICA, Targeted regions: Asia)

2. Call:

   Strengthening research on prediction, identification, modelling and surveillance of newly
    emerging infectious diseases in humans.
   Definition of research needs and priorities in Europe in the area of Emerging Infectious
    Epidemics.
                         Translating research for human health (8)
    2                 TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES



Cancer
•   Translating the knowledge on non-coding RNAs linked to the aetiology of cancer into novel
    diagnosis and therapy strategies.
•   Translating clinical ’omics’-technology (genomics, proteomics, metabolomics) into innovative
    cancer biomarkers aiding in early diagnosis, prognosis and treatment selection of cancer
    patients.
•   Genomic instability and genomic alterations in pre-cancerous lesions and/or cancer.
•   Novel cancer screening methods.
•   Optimising research on end of life care of cancer patients.
•   Understanding and fighting metastasis.
•   Improving targeted drug delivery to cancer cells for cancer therapeutics other than gene therapy
•   Developing high-throughput bioassays and models for human cancers in lower species.

2. Call:
•   Innovative combination clinical trials for multimodal cancer therapy.
•   Role of inflammation in tumour initiation and progression.
•   Epidemiology of gene-environment interactions involved in carcinogenesis.
•   Translating the hypoxic tumour microenvironment.
•   ERA-NET on optimisation of the use of cancer registries for cancer research purposes
•   Studying cancer aetiology in Latin America. (SICA)
                       Translating research for human health 9)
    2              TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES



Cardiovascular Disease

   Molecular basis of the inflammatory response and associated vascular remodelling in
    arteriosclerosis.
   Vascular remodelling in aneurysmal disease.
   Combating stroke.

2. Call:
   Congenital pathologies affecting the heart.
   Cell therapies for the treatment of heart ischemia.
   Organ imaging in CVD.
   Integrating pharmacogenomic approaches into the treatment of CVD.
                         Translating research for human health 10)
    2                 TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES



Diabetes and Obesity

   Early processes in the pathogenesis of type 1 diabetes and strategies for early prevention.
   Combined forms of diabetes in children.
   Insulin resistance as a key factor in the development of diabetes and metabolic syndrome.
   Pathophysiological mechanisms related to excess fat.
   A road-map for diabetes research.

2. Call:

   Nutritional signals and the development of new diabetes/obesity therapeutic agents.
   Markers and treatment for diabetic neuropathy complications.
   Geno- and phenotypical differentiation of type 2 subjects and monogenic subjects.
   Use of beta cell imaging in diabetes mellitus.
                         Translating research for human health 11)
    2                TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES



Rare Diseases

   Natural course and pathophysiology of rare diseases.
   Research capacity-building in the field of rare diseases.

Other Chronic Diseases

   Osteoarthritis.
   Inflammatory bowel disease.
   Osteoporosis: signalling pathways in bone formation and homeostasis.
   Genetic factors of Osteoporosis.
   Intervertebral disc degeneration: prevention and repair.
   Innovative concepts in chronic obstructive pulmonary disease pathogenesis (COPD).
   Hearing impairment and degeneration.
   Impairment of touch and proprioception at old age.
   Visual impairment and degeneration.
2. Call:
   Understanding and combating age-related muscle weakness.
   Translational research aiming for a treatment of urinary incontinence.
   Early processes in the pathogenesis of chronic inflammatory diseases.
    3      Optimising the delivery of health care to European Citizens (1)



Translating clinical research into clinical practice including better use of
medicines, and appropriate use of behavioural and organisational
interventions and health therapies and technologies
2.call:
    Implementation of research into healthcare practice
    Self-medication and patient safety
    Patient Safety Research Network
     Improving clinical decision making
    Better use of medicines.
    Continuity of clinical care.
    Patient self-management of chronic disease.


Quality, solidarity and sustainability of health systems
2.call:
    Evaluation of disease management programmes
    Health systems and long term care of the elderly
    Mobility of health professionals
    Health care human resource planning in nursing.
    Clinician working time and patient safety.
    Health outcome measures and population ageing.
    Trends of population health
    European system of Diagnosis-related groups (DRG)
    3      Optimising the delivery of health care to European Citizens (2)



Enhanced health promotion and disease prevention
2.call:
    Promoting healthy behaviour in children and adolescents
    Interventions addressing the gradient of health inequalities
    Public health interventions addressing the abuse of alcohol.
    Evaluation of suicide prevention strategies across and within European countries.
    Improve vaccination coverage


Horizontal Coordination and Support Actions across “Optimising the Delivery
of Health Care to European Citizens
2.call:

    Disease networks of centres of reference.
    Effectiveness of health investments.
    Patient mobility and access to information.
    Brokering research into policy.
    A road-map for ageing research.
    Health Services Research conference
    Mental health research conference.
    Public Health intervention research conference
    3     Optimising the delivery of health care to European Citizens (3)



Specific International Cooperation Actions for Health System Research
2.call:

   Epidemiological investigations into long-term trends of population health as
    consequence of socio-economic transitions, including life-style induced
    health problems. SICA (Mediterranean Partner countries, Russia, Eastern
    European and Central Asia)

   Universal and equitable access to health care and health financing. SICA
    (MCP, ACP, Asia and Latin America)

   Health care intervention research – optimising hospital care. SICA (Western
    Balkans.)

   Health care intervention research – improving pre-natal and maternal care.
    SICA (ACP and Mediterranean Partner Countries)
    4                      Other Actions across the Health Theme


Coordination and Support Actions across the Theme

•       Reinforcing the network of National Contact Points (NCP) for the Seventh Framework
        Programme under Health Theme by promoting transnational co-operation.)
•       Promoting participation of high-technology research intensive SMEs, operating in the
        biomedical engineering and other medical technology sectors´relevant to Health Theme.
•       Assessment and valorisation of project outcome for hightechnology and research intensive
        SME participating to Framework Programmes of Research in the healthcare sector.
•       Science communication actions.
•       Initiatives to foster dialogue and debate on health research issues of interest to the
        public.
•   Studies on the impact of EU legislation on health research and related developments and
    applications.
2.call:
•   Promotion and facilitation of international cooperation in areas relevant to the objectives of
    this theme. (SICA, ICPC)

Responding to EU policy needs (2.call)

       Paediatric medicinal products, Drug safety research, Living and work conditions,
        Health statistics, Tobacco Control
Technologieplattformen und
Gemeinsame Technologieinitiativen

 • Mobilisierung europäischer Ressourcen im Bereich Forschung,
   technologische Entwicklung und Innovation durch Zusammenbringen aller
   Akteure eines definierten Forschungsbereiches (Industrie, KMU,
   Universitäten, Endverbraucher)

 • Industriegetrieben

 • Gemeinsame Definition und Erstellung einer strategischen
   Forschungsagenda (mittel- bis langfristig)
   = Input zur Entwicklung der thematischen Programme im 7. RP

 • Einige wenige werden als Gemeinsame Technologieinitiativen (Joint
   Technology Initiatives) etabliert

 • Neuer Weg zur Realisierung von public-private partnerships auf EU-
   Ebene mit definierter rechtlicher Struktur
 Example „Innovative Medicines“ -
 en route to a „Joint Technology Initiative“

 Accelerated Development of safe and more effective medicines


 Revitalization of the the biopharmaceutical research and development (R&D)
  environment for Europe to become more competitive

 Improving the collaboration between all relevant actors from public and
  private organisations (public-private partnerships)

   Draft and Implementation of a European Research Agenda:
    Second version of the Strategic Research Agenda published recently

     First Calls   expected for end of 2007/beginning of 2008

     http://europa.eu.int/comm/research/fp6/index_en.cfm?p=1_innomed
     http://rp7.ffg.at/RP7.aspx_param_target_is_116120.v.aspx
    « Innovative Medicines »

2. version of the « Strategic Research Agenda »:

4 main topics:

    Safety:
     Early safety evaluation and risk assessment, creation of a European
     Centre for Drug Safety

    Efficacy:
     Predictive pharmacology, biomarker identification and validation, patient
     recruitment and risk assessment

    Knowledge Management:
     New technologies to control and analyse enormous quantities of
     information in an integrative and predictive way

    Education and Training:
     Bridge gaps in expertise required to strengthen the biopharmaceutical
     R&D process, creation of a European Medicines Research Academy
    Technologieplattform
    « Innovative Medicines »


   Contact in Austria:

     Univ. Prof. Dr. Hans Georg Eichler,
     Vice Rector of the Medical University in Vienna
     vr_forschung@meduniwien.ac.at
Relevante Themen der 1.
Ausschreibungen aus anderen Bereichen

Food, Agriculture, Fisheries and Biotechnology:
e.g. Fork to farm: Food (including seafood), health and well being

Information and Communication Technologies:
Objective ICT-2007.5.3: Virtual Physiological Human

Nanosciences, Nanotechnologies, Materials and new Production
Technologies:
„Creation of a critical and commented database on the health,
safety and environmental impact of nanoparticles“
„Substantial innovation in the European medical industry: development of
nanotechnology-based systems for in-vivo diagnosis and therapy (in
Coordination with topic HEALTH-2007-2.4.1-7 and HEALTH-2007-1.2-3 in
Theme 1 "Health")

Environment: Environment and Health

Security: Topic SEC-2007-1.3-05 Water distribution surveillance; Critical Infrastructure
          Protection
Inhalt


• Das 7. Rahmenprogramm im Überblick

• Themen der ersten Ausschreibungen zu „Gesundheit“

• Forschung zugunsten kleiner und mittlerer Unternehmen
  (KMU)
                   Zusammenarbeit zwischen Industrie
                        und F&E-Dienstleistern




• Forschung zugunsten von Kleinen und Mittleren Unternehmen
  (KMUs)

• Forschung zugunsten von KMU-Verbänden




25. Februar 2005             Präsentationstitel der FFG       34
                           Kennzeichen


• Themen: Bottom up –Ansatz (gesamtes Feld der Wissenschaft &
  Technologie)

• KMUs/KMU-Verbände lagern Forschung & technologische
  Entwicklung aus

• Flexibilität bezüglich der intellectual property rights




25. Februar 2005          Präsentationstitel der FFG            35
                             Aktivitäten


• Forschungs- und technologische Entwicklungsaktivitäten

• Demonstrationsaktivitäten

• Andere Aktivitäten (Trainings, dissemination activities)

• Management-Aktivitäten




25. Februar 2005          Präsentationstitel der FFG         36
                              Research for SMEs




                   Project participation scheme


                                                         RTD-
              Industry
                                                         performers



     at least 3 SMEs from                       at least 2
                                                universities
     at least 3 countries (MS, AS)              research centres
                                                industrial companies
                                                research performing SMEs


25. Februar 2005            Präsentationstitel der FFG                     37
                             Research for SMEs/
                             SME-Associations

                                     Research for SMEs       Research for SME
                                                             associations
Duration                             1 - 2 years             2 - 3 years

Number of partners                   5 - 10                  10 -15


Total budget*                        € 0.5 – 1.5 Million     € 1.5 – 4 Million


Activities                           R&D, demonstration,     R&D, demonstration,
                                     management, other       management, other activities
                                     activities




* Share of R&D carried out by RTD performers :
≥ 60%
25. Februar 2005                Präsentationstitel der FFG                              39
Source: European Commission
                             Einreichfristen:

•
•   Research for SMEs:      FP7-SME-2007-1
•                                 Einreichfrist: 4.September 200

•   Research for SME Associations:              FP7-SME-2007-2
•                                                     Einreichfrist: 1. Juni
    2007

•   Kontakt: Dr. Ines Haberl, ines.haberl@ffg.at

•        http://rp7.ffg.at/RP7.aspx
•        http://cordis.europa.eu/en/home.html




25. Februar 2005            Präsentationstitel der FFG                         40
Wichtige Dokumente zur Vorbereitung:



     Arbeitsprogramme + Annexes
     Guide for Applicants
     Rules for Participation
     Model Grant Agreement

 Leitfaden/Formular für Anbahnungsfinanzierung:
  rp7.ffg.at -> „Services der FFG“




Page 41/45                                         Y.Huber / FFG-EIP
Kontaktieren Sie uns!

Ihre Ansprechpartner für Life Sciences in der FFG/
Bereich Europäische und Internationale
Programme


Mag. Birgit Steininger
Leiterin des Referats für Biowissenschaften,
Nationale Kontaktstelle für Lebensmittel, Landwirtschaft und Biotechnologie (DW 4101)
birgit.steininger@ffg.at

Dr. Ylva Huber
Nationale Kontaktstelle für Gesundheit (DW 4102)
ylva.huber@ffg.at

Dr. Ines Haberl
Nationale Kontaktstelle für KMUs (DW 4103)
Ines.haberl@ffg.at

             e-mail: vorname.nachname@ffg.at, Tel: +43/57755-Durchwahl



Page 42/45                                                                        Y.Huber / FFG-EIP
Vielen Dank für Ihre Aufmerksamkeit
                   &
     viel Erfolg für Ihre Projekte
      im 7. Rahmenprogramm!

								
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