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home > neurology center > neurology a-z list > cerebral palsy index > cerebral palsy article

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Medical Author: Medical Author: Melissa Stoppler, M.D.

Medical Editor: Barbara K. Hecht, Ph.D.



While some people believe that the term "cerebral palsy" (CP) refers to a specific

disease, it actually refers to a range of disorders involved the control of muscles.

Cerebral palsy can be caused by many different problems. About half a million

people in the US have some form of cerebral palsy.

Cerebral palsy is usually congenital and becomes evident early in life. However, it

can be acquired later, for example, as a result of a head injury. Researchers now

believe that congenital cerebral palsy is caused by faulty cell development in the embryo in the early

stages of pregnancy. Maternal infection with the rubella virus (German measles) during pregnancy

and severe jaundice of the newborn (as from untreated Rh incompatibility) are some of the conditions

that have been associated with the development of cerebral palsy.

Children with cerebral palsy usually show symptoms within the first three years of life.

Read the rest of the cerebral palsy FAQ »







TOP SEARCHED CEREBRAL PALSY TERMS:

autism, cystic fibrosis, down syndrome,epilepsy, multiple sclerosis, parkinson's disease,spina bifida

What is cerebral palsy?

Cerebral palsy (CP) is an abnormality of motor function (as opposed to mental

function) and postural tone that is acquired at an early age, even before birth. Signs and

symptoms of cerebral palsy usually show in the first year of life.



This abnormality in the motor system is the result of brain lesions that are non-

progressive. The motor system of the body provides the ability to move and control

movements. A brain lesion is any abnormality of brain structure or function. "Non-

progressive" means that the lesion does not produce ongoing degeneration of the brain.

It is also implies that the brain lesion is the result of a one-time brain injury, that will

not occur again. Whatever the brain damage that occurred at the time of the injury is

the extent of damage for the rest of the child's life.



Cerebral palsy affects approximately one to three out of every thousand children born.

However, it is much higher in infants born with very low weight and in premature

infants.



Interestingly, new treatment methods that resulted in an increased survival rate of low-

birth weight and premature infants actually resulted in an overall increase number of

children with cerebral palsy. The new technologies, however, did not change the rate

of cerebral palsy in children born full term and with normal weight.



What are causes of cerebral palsy?

The term cerebral palsy does not indicate the cause or prognosis of the child with

cerebral palsy. There are many possible causes of cerebral palsy.



In full term infants the cause of cerebral palsy is usually prenatal and not related to

events at time of delivery; in most instances it is related to events that happened during

the pregnancy while the fetus is developing inside the mother's womb.



Premature birth is a risk factor for cerebral palsy. The premature brain is at a high risk

of bleeding, and when severe enough, it can result in cerebral palsy. Children that are

born prematurely can also develop serious respiratory distress due to immature and

poorly developed lungs. This can lead to periods of decreased oxygen delivered to the

brain that might result in cerebral palsy. A poorly understood brain process observed in

some premature infants is called periventricular leukomalacia. This is a disorder in

which holes form in the white matter of the premature infant's brain. The white matter

is necessary for the normal processing of signals that are transmitted throughout the

brain, and from the brain to the rest of the body.



White matter abnormalities are observed in many cases of cerebral palsy. Nevertheless,

it is important to recognize that the vast majority of premature infants, even those born

very prematurely, do not suffer from cerebral palsy. There have been many advances

in the field of neonatology (the care and study of problems affecting newborn infants)

which have enhanced the survival of very premature infants.



Other important causes of cerebral palsy include accidents of brain

development, genetic disorders, stroke due to abnormal blood vessels orblood clots, or

infections of the brain.



Even though it is widely believed that the most common cause of cerebral palsy is a

lack of oxygen to the brain during delivery (birth asphyxia), it is actually a very rare

cause of cerebral palsy. When cerebral palsy is the result of birth asphyxia, the infant

almost always suffers severe neonatal encephalopathy with symptoms during the first

few days of life. These symptoms include:



 seizures,



 irritability,



 jitteriness,



 feeding and respiratory problems,



 lethargy, and



 coma depending on the severity.

In rare instances, obstetrical accidents during particularly difficult deliveries can cause

brain damage and result in cerebral palsy. Conversely, it is very unlikely that cerebral

palsy symptoms would develop after a few years of age as a result of obstetrical

complications.



Child abuse during infancy can cause significant brain damage which, in turn, can lead

to cerebral palsy. This abuse often takes the form of severe shaking from a frustrated

parent or caregiver, causing hemorrhage in or just outside the brain. To further

compound the problem, many children with developmental abnormalities are at risk for

being abused. Thus, a child with cerebral palsy may be made significantly worse or

even killed by a single incident of abuse.



Despite the diversity of causes of cerebral palsy, many cases remain without a defined

cause. However, the enhanced ability to see the brain structure with magnetic

resonance imaging (MRI) and CT scans as well as improved diagnostic capabilities for

genetic disorders has made the number of such cases much lower.





Next: What are the types of cerebral palsy?



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