Summary
Savvy innovator and problem-solver in micro-biosensors & microfluidics-enabled
biochips (i.e., Lab-on-a-chip; applied in e.g., on-chip ELISA) for point-of-care & self-
testing clinical diagnostics by in-situ single use or in-vivo continuous monitoring of whole
blood analytes
Unique features for such field-deployable medical platform devices include painless,
submicroliter sample, one-step (no manual blood transfer), rapid and automatic readout
(no skill need), hand-held meter (battery powered), cheap consumables (disposable)
Experienced coordinator directing multidisciplinary team consisting of scientists and
engineers and collaborating with outside experts to facilitate device designs and
expedite bioassay protocols for performing detection of analytes of interest using the
integrated device system
Specialties:
Biosensors, Lab-on-a-chip, bioMEMS, microfluidic device, blood testing (single &
continuous), self-contained field deployable devices, homehealthcare devices,
transdermal drug delivery, transdermal sensors;
Innovator, coordinator, problem-solver, communicator, product/project manager, system
designer
Experiences:
VP Technology & Strategy; Senior Director & Chief Scientist of Biosensor & Biochip Research,
Kumetrix, Inc, CA
Business experiences:
Business development and negotiation, product management, outsourcing, coordination, multi-
entity cooperation
Technical experiences:
• Painfree platform biosensors for single-use and continuous monitoring self-testing blood
constitutes for monitoring of healthy status at home (e.g., blood glucose, lactate, alcohol)
• Miniaturized, easy-to-use, self-contained diagnostic platform systems (disposable bioassay
chip and handheld meter) providing painless, automated, rapid on-site assays for versatile blood
analytes and others (e.g., hemoglobin, insulin, enzyme activity; Zn, Pb, Cd at ppb level)
• Noninvasive alcohol monitor with excellent immunity, wide dynamic range and high sensitivity,
applicable in anti-drug compliance and prevention of drunk driving in conjunction with
automobile interlock system
• Drug-independent, self-administered, and painless transdermal drug delivery patches
applicable to high molecular weight and/or water soluble therapeutic agents (e.g., drugs,
vaccines) having delivery depth and rate controllable over a wide range
• NIH fund reviewer, managing editor for journal “Frontiers in Bioscience” and a regular reviewer
for peer-review journals
Honors:
1. PI, "Automatic Multi-Analyte In-Situ Bioassay for Monitoring Exposure to Toxic
Metals”, NIH (NIEHS) Grant
2. PI, “Lactate-Oxygen Biosensors for Surgical Monitoring”, NSF Grant
3. Co-investigator (acting PI), “Amplified Biothreat Signature Detection Microarray”, DoD
Army Contract
4. PI, “Minimally Invasive Microsensor for Blood Alcohol Assay”, NIH (NIAAA) Grant
5. A 2nd award recipient of the “Development of Science and Technology” for “The
Fundamental Studies in Bioelectro-analytical Chemistry”, the State Department of
Education of China
Invited Presentations
1. Medical Diagnostics Technology Based on BioMEMS, State Technology and Devices
Seminar (EE 298-12), Microlab, UC Berkeley, CA, April, 2007
2. Emerging Biosensor Technologies: Point-Of-Care Applications, Wound Healing
Laboratory (eminent Prof. Thomas K Hunt’s lab), Department of Surgery, UC San
Francisco, CA, November, 2005
http://www.linkedin.com/in/jianweimo
2