BIOSENSORS

							                  BIOSENSORS AND INSTRUMENTATON


1. Introduction
       Concepts and components of a biosensor - principles of operation,
integration of biosensor in instrumentation.


2. Preparation of biosensor
      Biomolecules used in biosensors and their properties, general
Immobilization techniques for (Optical-detection biosensor, thermal-detection
biosensor, electrochemical biosensor etc.,) behaviour of different types of
biosensors.


3. Types of biosensor
      Enzyme based biosensor; (glucose biosensor, cholesterol biosensor),
microbial immunobiosensor and their characteristics.


4. Applications of biosensors
      Validation (Specificity, Speed, Simplicity, Capability), application of
biosensor in environment, Microbiology: bacterial and viral analysis, Food and
beverage production and analysis, Clinical Diagnosis.


5. Instrumentation of biosensor
      Transducers: Optical transducers, Fluroescensce transducers, Acoustic
transducer.
      Polarizable and non-polarizable electrodes acoustic, plasmon
resonance, holographic and microengineered sensors for monitoring low
molecular weight anlaytes, proteins, DNA and whole cells.


Reference books:
1. Biomolecular sensors, Eds.: Electra Gizeli and Christopher R.Lowe, Taylor
   and Francis, London (2002).
2. Cass,A.E.G, Biosensors: A Practical Approach, ORL Press (1990).
3. Jon Cooper and Tony Cass, Biosensors: A Practical Approach, Oxford
   Press (2004).




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