bioinformatics

Document Sample
bioinformatics Powered By Docstoc
					                     BIOINFORMATICS @ STG


                            CORE MODULES
MODULE I
INTRODUCTION TO BIOLOGICAL SYSTEMS

   Structure and function of Prokaryotic and Eukaryotic Cell
   Cell division

INTRODUCTION, STRUCTURE AND FUNCTIONS OF
PROTEINS AND NUCLEIC ACIDS

   Amino acids and proteins
   Nucleic acid

MOLECULAR BIOLOGY

   Structure and function of gene
   Central dogma of molecular biology
   Molecular biology techniques: DNA fingerprinting, blotting techniques, cDNA
    construction and cloning techniques

MODULE II

WINDOWS, INTERNET AND LINUX
     Windows operating system
     Networking essentials
     Internet
     Linux operating systems

PROGRAMMING AND DATA MANAGEMENT
     C and C++
     Bio-perl
     Oracle 8i
     Visual basic




                                        1
MODULE III

CONCEPTS AND PRINCIPLES

     Introduction to Bioinformatics
     History
     The Human Genome Project
     Model Organisms
     Sequencing methods
     Base calling, Genome mapping and Assembly
     Genomics
     Proteomics
     Metabolomics
     Pharmacogenomics and applications
     Single Nucleotide Polymorphisms (SNPs)
     Principles of Sequence Comparison
     Alignment algorithms: Dynamic Programming, Needleman- Wunsch and Smith-
      Waterman
     Amino acid Substitution Matrices: BLOSSUM, PAM
     Database Searches: FASTA, BLAST
     Pattern Databases: PROSITE, PRINTS and BLOCKS
     Protein Domain Families: Pfam, SMART and Interpro
     Building Phylogenetic Trees
     Principles of Genome Annotation
     The evolution of Protein Structure and Function
     Structural Classification of Proteins: CATH and SCOP
     Protein Structure Prediction: Comparative and Ab initio methods
     Microarray Technology and Data Analysis.


  BIOINFORMATICS TOOLS AND TECHNIQUES
         Bioinformatics Organizations: NCBI,EMBL,DDBJ,TIGR


                                          2
   Databases: GenBank, NSD, DDBJ, SWISS-PROT, TrEMBL, PDB
   Sequence File Formats: FASTA, PIR, GDE, MSF
   Genome Resourses: Human, Mouse, C.elegans, Plants, Arabidopsis
   Restriction Enzyne Analysis: Neb Cutter
   Masking the Repeats: RepeatMasker
   Codon Usage Analysis: Codon Usage Database
   Primer Designing: Primer3
   Finding the ORF: NCBI ORF Finder, Diogenes
   Gene Finding: GENSCAN, GENOMESCAN, GRAIL
   Translation: Translate
   Pairwise Sequence Alignment (Local): BLAST, FASTA
   Pairwise Sequence Alignment (Global): ALIGN
   Multiple Alignment: ClustalW
   Phylogenetic Analysis: PHYLIP
   Genome Comparison: PipMaker
   Motif Analysis: MEME
   Domain Identification: PANAL
   Protein Structure Classification: CATH, SCOPE
   Secondary Structure Prediction: Jpred
   Protein Threding: 3D-PSSM, PhD
   Homology Modeling: SWISS-MODEL
   Model Verification: VERIFY-3D
   Metabolic Pathways: KEGG
   2D-PAGE Analysis: Melanie Viewer
   3D structure Visualization and Analysis: Rasmol, Swiss-PDBViewer
   EXPASY Tools
Bioinformatics Organizations
       NCBI
       EBI
       DDBJ
       TIGR


                                    3
              Human genome Project


MODULE IV

CHEMINFORMATICS

        Introduction
        Drug Databases
           Chemical Databases
          Chem-Softwares

    COMBINATORIAL CHEMISTRY

        Introduction
        Techniques
        Applications

    DRUG DISCOVERY

        Introduction
          Technologies:QSAR and DOCKING
          Commercial viability

MODULE V
BIO-SOFTWARE’S

          EXPRESSION
          VECTOR NTI
          EMBOSS

Project on Genome or Proteome analysis.

Normal Track : 6 Months (3 days in a week)
Fast Track : 3 Months ( 5 days in a week )




 STG International LTD, #2934/35E, 3rd Floor, above old Food world,
 Vijaynagar, Bangalore- 40, (Contact no : 080-41493098, 9739011252 )
.



                                          4

				
DOCUMENT INFO
Shared By:
Categories:
Tags:
Stats:
views:7
posted:12/10/2011
language:
pages:4