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Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





11q23 C13390 C13390 (11q23 ) C13390 A chromosome band present on 11q

(11q23 )









12p C13532 C13532 (12p) C13532 Proximal (short) arm of chromosome 12

(12p)









14q C13538 C13538 (14q ) C13538 Distal (long) arm of chromosome 14

(14q )









6q C13560 C13560 (6q) C13560 Distal (long) arm of chromosome 6

(6q)









7-Aminoactinomycin D C72904 Added to EVS on 13 C72904 (7- C72904 (7- A fluorescent nucleic acid dye which selectively 2006 152

March 2013 Aminoactinomycin D) Aminoactin binds GC sequences in double-stranded DNA.

omycin D) It has a molecular weight of 1270.5, an

absorbance maximun at 546 nm, and emission

maximum at 647 nm. It is commonly used to

9p C13563 C13563 (9p ) C13563 discriminate viable from non-viable cells.

Proximal (short) arm of chromosome 9

(9p )









Abnormality C9440 C9440 (Abnormality ) C9440 A condition that differs from the usual physical

(Abnormalit or mental state.

y)







abortion C35221 C35221 (abortion) C35221

(abortion)









C75520

(Absorbable

)



Absorbable C75520 C75520(Absorbable) Capable of being taken up or taken in.

ACA positive C13198 (Centromere (ACA

), C16295 (antibody) positive)









Accident C34340 C34340 Accident C34340 NCI|An unforeseen and unplanned event or 2900

(Accident) circumstance frequently causing loss or injury.









Acquired Pure Red Cell C70548 C70548 (Acquired Pure C70548

Aplasia Red Cell Aplasia) (Acquired

Pure Red

Cell

Aplasia)

acute leukemia C9300 C9300 (acute C9300

leukemia) (acute

leukemia)







acute leukemia of ambiguous C7464 C7464 (acute leukemia C7464

lineage of ambiguous lineage) (acute

leukemia of

ambiguous

lineage)

Acute Lymphoblastic C3167 C3167 (Acute C3167

Leukemia Lymphoblastic (Acute

Leukemia) Lymphoblas

tic

Leukemia)

Acute Myeloid Leukemia AML, ANLL C3171 C3171 (Acute Myeloid C3171

Leukemia) (Acute

Myeloid

Leukemia)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





Acute_Graft_Versus_Host_Di C4980 C4980 NCI|A syndrome of immologically mediated 2900

sease (Acute_Graf tissue damage occurring following allogeneic

C4980 t_Versus_H transplant usually affecting the skin, liver, and

Acute_Graft_Versus_H ost_Diseas gi tract. Onset is usually within one hundred

ost_Disease e) days of transplantation or immunologic

Add C64911 C64911 (Add ) C64911 manipulation. with others so as to increase

To join or unite

(Add ) size, quantity, or scope.









add(14q) C64911 (Add ), (add(14q)) To join or unite with others so as to increase 2011 33

C13538 (14q ) size, quantity, or scope._Distal (long) arm of

chromosome 14







Adenosine_Deaminase_Defic C3962 C3962 C3962

iency (Adenosine_Deaminas (Adenosine

e_Deficiency) _Deaminas

e_Deficienc

y)

adenovirus C14179 C14179 adenovirus C14179 NCI|A group of DNA containing viruses which 2100 430

(adenovirus infect mammals and are capable of causing

) respiratory disease, including one form of the

common cold.



Adjuvant Therapy C15675 C15675 (Adjuvant C15675

Therapy) (Adjuvant

Therapy)







Administered C25382 C25382 (Administered C25382 The act of having given something (e.g., a

) (Administer medication or test).

ed )







Administration C25409 C25409 C25409 The act of the dispensing, applying, or

(Administration) (Administrat tendering of something to another, such as

ion) administration of a medicine.







Adverse Event C41331 C41331 (Adverse C41331 Any unfavorable or unintended symptom, sign,

Event ) (Adverse or disease including an abnormal laboratory

Event ) finding) temporally associated with the use of a

medical treatment or procedure that may or

may not be considered related to the medical

age C25150 C25150 (age) C25150 treatment or procedure. Such events can be

(age)









Albumin C214 C214 (Albumin) C214 A family of globular proteins found in many

(Albumin) plant and animal tissues that tend to bind a

wide variety of ligands. Albumin is the main

protein in blood plasma. Low serum levels

occur in conditions associated with

Albumin Measurement C64431 C64431 (Albumin C64431 malnutrition, inflammation and liver and kidney

A quantitative measurement of albumin

Measurement ) (Albumin present in a sample

Measureme

nt )



Alemtuzumab Campath 1-H C1681 C1681 A recombinant DNA-derived humanized 2006 89

(Alemtuzum monoclonal antibody directed against the cell

ab) surface glycoprotein, CD52. Alemtuzumab is

an IgG1 kappa with human variable framework

and constant regions, and complementarity-

Alkylating Agent C223 C223 (Alkylating Agent C223 determining replace hydrogen atom(s) in

Agents that regions derived from a rat

) (Alkylating biologically active molecules with alky

Agent ) radical(s), hindering proper function. Alkylating

agents exhibit cytotoxic effects through the

alkylation of DNA, resulting in strand cross-

Allele C16277 C16277 (Allele) C16277 linking, ultimately inhibiting DNA replication

Mutually exclusive alternative forms of the

(Allele) same gene occupying the same locus on

homologous chromosomes, differing in DNA

sequence and governing the same

biochemical and developmental process.

Allelotyping C19822 C19822 (Allelotyping) C19822

(Allelotyping

)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





Allogenic Allogeneic C28343 C28343 (Allogenic ) C28343 Taken from different individuals of the same

(Allogenic ) species. Also called allogeneic.









Alteration C28344 C28344 (Alteration ) C28344 A change resulting in something that is

(Alteration ) different from the original.









Alternative Hematopoietic C70632 C70632 (Alternative C70632

Cell Transplantation Hematopoietic Cell (Alternative

Transplantation) Hematopoie

tic Cell

Transplanta

AML C3171 C3171 (AML) tion)

C3171

(AML)









Analysis C25391 C25391 (Analysis) C25391 Examination and interpretation; the process of

(Analysis) identifying an issue to be understood and

addressed, modelling the issue, investigating

the model results, interpreting the results, and

possibly making a recommendation. The

Anatomic Site C13717 C13717 (Anatomic C13717 Named locations of to the examination and

concept also refers or within the body

Site ) (Anatomic

Site )







And/Or C48928 C48928 (And/Or) C48928 Used to indicate that either or both of two items

(And/Or) or options may be valid.









anemia C2869 C2869 (anemia) C2869

(anemia)









Anthracycline Antineoplastic C1594 C1594 (Anthracycline C1594 Antineoplastic antibiotics isolated from the

Antibiotic Antineoplastic Antibiotic (Anthracycli bacterium Streptococcus peucetius var.

) ne caesius or derived synthetically. Anthracycline

Antineoplas antibiotics exhibit potent cytotoxic properties

tic Antibiotic due to their ability to intercalate into DNA and

anti CD2 antibody 03-24-08: Working with C15174 (CD2 Antigen ) An antigen that functions as II, co-receptor or

interact with topoisomerase a thereby 2006 74

review committee to ): C16295 (antibody) accessory molecule in the T-cell receptor

determine appropriate complex, which is involved in helper and

concept cytotoxic T-lymphocyte adhesion and

activation. The molecule is expressed on the

anti CD3 antibody 03-24-08: Working with C38897 (CD3 cell surface of the majority of peripheral T-

Consisting of cell surface type I membrane 2006 75

review committee to Complex): C16295 Delta, Epsilon, Gamma, Zeta, and Eta protein

determine appropriate (antibody) subunits with ITAM domains and noncovalently

concept associated with the disulfide bound

heterodimeric alpha/beta and gamma/delta

anti CD34 antibody Use alternate definiition C17280 (CD34 TCR, the CD3 complex couples receptor

Alternate Definition (MSH2001): Glycoproteins

for CD34 antigen Antigen ): C16295 found on immature hematopoietic cells and

(antibody) endothelial cells. They are the only molecules

to date whose expression within the blood

system is restricted to a small number of

anti CD4 antibody C16300 (CD4 Antigen progenitor cells in the bone marrow._A type of

CD4 Antigen, encoded by the CD4 gene, is a T- 2006 76

)+E506 cell surface glycoprotein. CD4 has a role in cell-

cell interactions and may act in signal

transduction. CD4 is a accessory protein for

MHC class-II antigen/T-cell receptor interaction

anti CD5 antibody C73124 (T-Cell and functions to initiate or augment the early

T-cell surface glycoprotein CD5 (495 aa, ~54 2006 77

Surface Glycoprotein kDa) is encoded by the human CD5 gene. This

CD5 ): C16295 protein may be involved in regulating the

(antibody) proliferation of T-cells._A type of protein made

by B lymphocytes in response to a foreign

anti CD6 antibody C73129 (T-Cell substance (antigen). Each antibody only binds

T-cell differentiation antigen CD6 (668 aa, ~72 2006 78

Differentiation Antigen kDa) is encoded by the human CD6 gene. This

CD6 ) protein plays a role in the adherence of

immature thymus cells to thymic epithelial

cells._A type of protein made by B

anti CD7 antibody C38935 (T-Cell Antigen lymphocytes thymocytes and mature

Expressed inin response to a foreign T cells by 2006 79

CD7 ): C16295 human CD7 Gene (Immunoglobulin

(antibody) Superfamily), 240-aa 25-kDa (precursor) T-

Cell Antigen CD7 is a cell surface type I

transmembrane glycoprotein that interacts with

SECTM1, contains an Ig-like domain, and is

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





anti CD8 antibody 03-24-08: Request 2006 80

pending in EVS









Anti MPO C16553 (ELISA ), (Anti MPO) 2400 452

C71145

(Myeloperoxidase ),

C16295 (antibody)



Anti Pr3 C16553 (ELISA ), (Anti Pr3) 2400 451

C17548 (Proteinase-3),

C16295 (antibody)







antibody C16295 C16295 (antibody) C16295 A type of protein made by B lymphocytes in

(antibody) response to a foreign substance (antigen).

Each antibody only binds to a specific antigen,

helping to destroy the antigen directly or by

assisting white blood cells to destroy the

Antibody Coated Plate C72896 Added to EVS on 13 C72896 (Antibody C72896 antigen. medium with a coating of monoclonal

A plastic 2006 62

March 2009 Coated Plate ) (Antibody or polyclonal antibodies, often used to select or

Coated deplete a population of cells which are passed

Plate ) over the medium.



Anticardiolipin IgG Antibody C70990 C70990 C70990 An IgG autoantibody directed against

(Anticardiolipin IgG (Anticardioli cardiolipin. It is associated with blood clotting

Antibody ) pin IgG complications.

Antibody )



Anticardiolipin IgM Antibody C70619 C70619 (Anticardiolipin C70619

IgM Antibody) (Anticardioli

pin IgM

Antibody)



C75525

(Anti-CD25

Monoclonal Any monoclonal antibody directed against the

Anti-CD25 Monoclonal Antibody) alpha subunit of the human interleukin 2

Antibody C75525 C75525(Disturbance) receptor.

Anti-CD52 Monoclonal C72960 Added to EVS on 13 C72960 (Anti-CD52 C72960 Any monoclonal antibody directed against the 2006 86

Antibody March 2015 Monoclonal Antibody ) (Anti-CD52 cell surface glycoprotein CD52, regardless of

Monoclonal the antibody type (e.g., rat, mouse,

Antibody ) humanized).



Antigen C268 C268 (Antigen) C268 Any substance, generally a protein, that

(Antigen) stimulates the immune system and elicits an

immune response. Recognition by the immune

system elicits either a T-lymphocyte response,

recognizing processed antigens, or a B-

Antileukemic Agent C75574 C75574(Antileukemic C75574 lymphocyte response, producing antibodies

Any substance that treats, prevents, or inhibits

Agent) (Antileukem the development of leukemia.

ic Agent)







Antinuclear Antibody C70547 C70547 (Antinuclear C70547

Antibody) (Antinuclear

Antibody)







Antiphospholipid_Syndrome C61283 C61283 C61283

(Antiphospholipid_Synd (Antiphosph

rome ) olipid_Synd

rome )



Aplastic Anemia due to C61231 C61231 (Aplastic C61231

Hepatitis Anemia due to (Aplastic

Hepatitis) Anemia due

to Hepatitis)



Aplastic Anemia due to C61231 C61231 (Aplastic C61231

Hepatitis Anemia due to (Aplastic

Hepatitis) Anemia due

to Hepatitis)



Arrhythmia C2881 C2881 (Arrhythmia) C2881

(Arrhythmia

)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





Arrival Arrived C53463 C53463 (Arrival) C53463 The act of reaching a destination.

(Arrival)









arthritis C2883 C2883 (arthritis) C2883

(arthritis)









Assessment C25217 C25217 (Assessment ) C25217 The act of judging the value, significance, or

(Assessme extent of something.

nt )







Assignment C25426 C25426 (Assignment ) C25426 An allotting or an appointment to a particular

(Assignmen person or use, or for a particular time or object.

t)







At C25427 C25427 (At) C25427 Used to indicate position, location, or state.

(At)









Atypical_Burkitt_s_Burkitt_s- C6917 C6917 C6917

Like_Lymphoma (Atypical_Burkitt_s_Bur (Atypical_B

kitt_s-Like_Lymphoma urkitt_s_Bur

) kitt_s-

Like_Lymph

Autoimmune Disease C2889 C2889 (Autoimmune oma )

C2889 A disorder resulting from loss of function or

Disease) (Autoimmun tissue destruction of an organ or multiple

e Disease) organs, arising from humoral or cellular

immune responses of the individual to his own

tissue constituents. It may be systemic (e.g.,

autologous C28000 C28000 (autologous) C28000 systemic lupus erythematosus), or organ

(autologous

)







Autopsy C25153 C25153 autopsy C25153 NCI|A postmortem examination of the body 2100 426

(Autopsy) that includes an examination of the internal

organs and structures after dissection to

determine the cause of death and the nature of

pathological changes.

Bacteria C14187 C14187 (Bacteria ) C14187 Unicellular, prokaryotic organisms that

(Bacteria ) reproduce by cell division and usually have cell

walls; can be shaped like spheres, rods or

spirals and can be found in virtually any

environment.|

B-cell /small lymphocytic C7540 C7540 (B-cell /small C7540 (B-

leukemia lymphocytic leukemia) cell /small

lymphocytic

leukemia)



BCR-ABL_Oncoprotein C16325 C16325 (BCR- C16325

ABL_Oncoprotein ) (BCR-

ABL_Oncop

rotein )



BCR-ABL1 Fusion Protein C36715 C36715 (BCR-ABL1 C36715

Expression Fusion Protein (BCR-ABL1

Expression) Fusion

Protein

Expression)

Begin start, C25431 C25431 (Begin) C25431

(Begin)









Beta-2-Microglobulin Protein C62657 C62657 (Beta-2- C62657 Beta-2-microglobulin protein (119 aa, ~14 kDa)

Microglobulin Protein ) (Beta-2- is encoded by the human B2M gene. This

Microglobuli protein plays a role in immune responses and

n Protein ) is a key component of major histocompatibility

complex class I molecules. The protein is

Biopsy C15189 C15189 (Biopsy) C15189 The removal of surface of cells and is utilized

localized to the tissue specimens or fluid from

(Biopsy) the living body for microscopic examination,

performed to establish a diagnosis.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





Blast Cell C12918 C12918 (Blast Cell) C12918 Blast cells are in an immature

(Blast Cell) (undifferentiated) stage in cellular

development, occurring before the appearance

of the definitive characteristics exhibited by

fully differentiated cells.

bleomycin C313 C313 (bleomycin) C313

(bleomycin)









Blinded clinical study C70840 C70840 (blinded C70840 NCI|A clinical study that is designed using a 2100 9

clinical study) (Blinded procedure in which one or more parties to the

clinical study [subject(s), investigator(s), monitor,

study) or/and data analyst(s)] are kept unaware of the

treatment assignment(s).

Blister C75564 C75564(Blister) C75564 An elevation of the skin filled with serous fluid.

(Blister)









Blood C12434 C12434 (Blood) C12434 A liquid tissue; its major function is to transport

(Blood) oxygen throughout the body. It also supplies

the tissues with nutrients, removes waste

products, and contains various components of

the immune system defending the body

Blood Transfusion C15192 C15192 (Blood C15192 against infection. Several hormones also travel

The infusion of components of blood or whole

Transfusion ) (Blood blood into the bloodstream. The blood may be

Transfusion donated from another person, or it may have

) been taken from the person earlier and stored

until needed.

Bloom Syndrome C2903 C2903 (Bloom C2903 Bloom syndrome is an autosomal recessive

Syndrome) (Bloom disorder associated with mutations in BLM

Syndrome) gene encoding protein that belongs to the

family of DNA helicases. It is characterized by

predisposition to cancer, immunodeficiency,

Bone Marrow C12431 C12431 (Bone Marrow C12431 high sensitivity to UV tissue in the instability

The soft, sponge-like and genomiccenter of of

) (Bone bones that produces white blood cells, red

Marrow ) blood cells, and platelets.







bortezomib C1851 C1851 (bortezomib) C1851

(bortezomib

)







breast carcinoma C4872 C4872 (breast C4872

carcinoma) (breast

carcinoma)







Bronchoalveolar_Lavage C51913 C51913 C51913 NCI|Washing out the bronchi and alveoli by 2100 423

Bronchoalveolar_Lava (Bronchoalv flushing with a fluid.

ge eolar_Lava

ge)



Buffy Coat Preparation C72895 Added to EVS on 13 C72895 (Buffy Coat C72895 A process using centrifugation of whole blood 2006 47

March 2008 Preparation ) (Buffy Coat to obtain a white blood cell layer highly

Preparation enriched for neutrophils, lymphocytes,

) monocytes and progenitor cells.



Burkitt cell leukemia C7400 C7400 (Burkitt cell C7400

leukemia) (Burkitt cell

leukemia)







Burkitt's lymphoma C2912 C2912 (Burkitt's C2912

lymphoma) (Burkitt's

lymphoma)







busulfan C321 C321 (busulfan) C321

(busulfan)









C3 C21527 (Complement (C3) 2400 380

Component 3 )

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





C4 C70618 (Complement (C4) 2400 381

Component-4 )









Campath NOS Working with EVS (Campath 2006 87

NOS)









Campath-1G C72959 Added to EVS on 13 C72959 (Campath-1G C72959 A rat IgG2b monoclonal antibody directed 2006 88

March 2014 ) (Campath- against the cell surface glycoprotein CD52. It is

1G ) used in HCT to prevent GVHD by eliminating T

cells via antibody dependent cell cytotoxicity in

vivo.

c-ANCA IFA C17370 (Fluorescent (c-ANCA 2400 453

Antibody Technique ), IFA)

C17548 (Proteinase-3)

, C16295 (antibody)



c-ANCA Positive C17998 (Unknown), (c-ANCA 2400 450

C25294 (laboratory Positive)

procedure), C17548

(Proteinase-3) ,

C16295 (antibody)

Carcinoma C2916 This concept refers C2916 (Carcinoma ) C2916 A malignant tumor arising from epithelial cells.

specifically to malignant (Carcinoma Carcinomas that arise from glandular

tumors that begin in ) epithelium are called adenocarcinomas, those

epithelial cells. For that arise from squamous epithelium are called

generic "cancer," squamous cell carcinomas, and those that

please use the concept arise from transitional epithelium are called

C9305 (Malignant transitional cell carcinomas. Morphologically,

Neoplasm ). the malignant epithelial cells may display

abnormal mitotic figures, anaplasia, and

necrosis. Carcinomas are graded by the

degree of cellular differentiation as well,

moderately, or poorly differentiated.

Carcinomas invade the surrounding tissues

and tend to metastasize to other anatomic

sites. Lung carcinoma, skin carcinoma, breast

carcinoma, colon carcinoma, and prostate

carcinoma are the most frequently seen

carcinomas.



Carmustine C349 C349 (Carmustine) C349 An antineoplastic nitrosourea. Carmustine 2400 61

(Carmustine alkylates and cross-links DNA during all

) phases of the cell cycle, resulting in disruption

of DNA function, cell cycle arrest, and

apoptosis. This agent also carbamoylates

proteins, including DNA repair





category C25372 C25372 (category) C25372

(category)









CD2 Antigen C15174 C15174 (CD2 Antigen C15174 An antigen that functions as a co-receptor or

) (CD2 accessory molecule in the T-cell receptor

Antigen ) complex, which is involved in helper and

cytotoxic T-lymphocyte adhesion and

activation. The molecule is expressed on the

CD20 Antigen C38896 C38896 (CD20 C38896 cell surfaceduring B-cell ontogeny (earlyT-

Expressed of the majority of peripheral pre-B- 2111 75

Antigen) (CD20 cell to plasma cell) by human CD20 Gene

Antigen) (MS4A Family), 297-aa 33-kDa CD20 Antigen

is a phosphorylated cell surface integral

membrane protein shown to participate in B-

CD20+ Cells CD20 C38896 (CD20 cell proliferation, development, and 2111 75

Antigen):C25626

(Present):C12508 (cell)







CD3 Complex C38897 C38897 (CD3 C38897 Consisting of cell surface type I membrane

Complex) (CD3 Delta, Epsilon, Gamma, Zeta, and Eta protein

Complex) subunits with ITAM domains and noncovalently

associated with the disulfide bound

heterodimeric alpha/beta and gamma/delta

CD3+ cells C38897 (CD3 TCR, the CD3 complex couples receptor

Consisting of cell surface type I membrane 2006 148

Complex):C25626 Delta, Epsilon, Gamma, Zeta, and Eta protein

(Present):C12508 (cell) subunits with ITAM domains and noncovalently

associated with the disulfide bound

heterodimeric alpha/beta and gamma/delta

TCR, the CD3 complex couples receptor

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





CD34 Antigen C17280 Use the alternate C17280 (CD34 C17280 Alternate Definition (MSH2001):

MSH2001 definition Antigen ) (CD34 Glycoproteins found on immature

Antigen ) hematopoietic cells and endothelial cells. They

are the only molecules to date whose

expression within the blood system is restricted

CD34 Selection Do not use concept C17280 (CD34 to a small number of progenitor cells in the

C70621. At some point Antigen ), C71257

that concept will be (Positive Selection )

retired. Be sure to use

alternate definition for

CD34+ cells CD34 Antigen.

Use alternate definiition C17280 (CD34 Alternate Definition (MSH2001): Glycoproteins 2006 147

for CD34 antigen Antigen ):C25626 found on immature hematopoietic cells and

(Present):C12508 (cell) endothelial cells. They are the only molecules

to date whose expression within the blood

system is restricted to a small number of

CD4 Antigen C16300 C16300 (CD4 Antigen C16300 progenitor cells in the bone marrow._Being or T-

CD4 Antigen, encoded by the CD4 gene, is a

) (CD4 cell surface glycoprotein. CD4 has a role in cell-

Antigen ) cell interactions and may act in signal

transduction. CD4 is a accessory protein for

MHC class-II antigen/T-cell receptor interaction

CD4+ cells C16300 (CD4 Antigen (CD4+ CD4functions encoded by augment gene, is a T-

and Antigen, to initiate or the CD4 the early 2006 149

):C25626 cells) cell surface glycoprotein. CD4 has a role in cell-

(Present):C12508 (cell) cell interactions and may act in signal

transduction. CD4 is a accessory protein for

MHC class-II antigen/T-cell receptor interaction

CD40 Ligand Deficiency C61244 C61244 (CD40 Ligand C61244 and functions to initiate or augment the early

Deficiency) (CD40

Ligand

Deficiency)



CD56+ Cells CD56 C25276 (CD56+

(Neural Cell Adhesion Cells)

Molecule):C25626

(Present):C12508 (cell)



CD8+ cells 03-24-08: Request (CD8+ 2006 150

pending in EVS cells)









CDW52 Antigen C38908 Be sure to use the C38908 ( CDW52 C38908 Encoded by the CDW52 wt Allele, CDW52 is a 2006 88

definition specified Antigen ) (CDW52 glycosylphosphatidylinositol-anchored

here. As of 13 March Antigen ) glycoprotein expressed on the surface of

2008, this was the essentially all normal and malignant B and T

caDSR definition and cells, a majority of monocytes, macrophages

cell C12508 not the NCI Thesaurus C12508 (cell) C12508 and smallest units of living structure capable of

The natural killer (NK) cells, a subpopulation of

(cell) independent existence, composed of a

membrane-enclosed mass of protoplasm and

containing a nucleus or nucleoid.



Cell Sorting Cell C16406 C16406 (Cell Sorting) C16406 Techniques and methods for separating cells 2006 48

Separator (Cell (usually viable) based on a variety of criteria

Sorting) for separation, such as size or density, non-

specific surface properties, or specific surface

properties. Examples include cell affinity

Cell Wash C76322 C76322(Cell Wash C76322 chromatography and centrifugation using

The process of applying a solvent (e.g., water)

synonym: Wash synonym: Wash) (Cell Wash or a solution (e.g., SSC/SDS) to a biomaterial

synonym: or an array to remove impurities or unwanted

Wash) compounds.



Cellular Therapy C70601 C70601 (Cellular C70601

Therapy) (Cellular

Therapy)







Central Nervous System C5440 C5440 (Central C5440

Leukemia Nervous System (Central

Leukemia ) Nervous

System

Leukemia )

Central_Nervous_System CNS C12438 C12438 C12438 The part of the nervous system that consists of

(Central_Nervous_Syst (Central_Ne the brain, spinal cord, and meninges.

em) rvous_Syst

em)



Centromere C13198 C13198 (Centromere ) C13198 The nonstaining primary constriction of a

(Centromer chromosome which is the point of attachment

e) of the spindle fiber; provides the mechanism of

chromosome movement during cell division;

the centromere divides the chromosome into

two arms, and its position is constant for a

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





Cerebrovascular_Disorder C2938 C2938 C2938

(Cerebrovascular_Diso (Cerebrova

rder) scular_Diso

rder)



Change C25446 C25446 (Change) C25446 NCI|The act of alteration or modification;

(Change) changed or altered in form or character.









Chemotherapy C15632 C15632 C15632

(Chemotherapy) (Chemother

apy)







Chimerism C62582 C62582 chimerism C62582 NCI|The occurrence in an individual of two or 2100

(Chimerism) more cell populations of different chromosomal

constitutions, derived from different individuals.

This contrasts with mosaicism in which the

different cell populations are derived from a

Chronic Graft Versus Host C4981 C4981 NCI|A individual. of immologically mediated

single syndrome 2900

Disease (Chronic tissue damage occurring following allogeneic

Graft transplant and may affect multiple organs with

Versus Host manifestations similar to autoimmune

diseases. Onset is usually within three years of

Disease) Disease

C4981 Chronic Graft Versus Host

chronic myelomonocytic C3178 C3178 (chronic C3178 transplantation or immunologic manipulation.

leukemia (CMML) myelomonocytic (chronic

leukemia (CMML)) myelomono

cytic

leukemia

Chronic Myeloproliferative MPS C4345 C4345 (Chronic (CMML))

C4345 Chronic myeloproliferative disorders (CMPDs)

Disorder Myeloproliferative (Chronic are clonal hematopoietic stem cell disorders,

Disorder) Myeloprolife characterized by proliferation in the bone

rative marrow of one or more of the myeloid (i.e.,

Disorder) granulocytic, erythroid, and megakaryocytic)

Chronic_Lymphocytic_Leuke C3163 C3163 C3163 lineages. The proliferation is associated with

mia (Chronic_Lymphocytic_ (Chronic_Ly

Leukemia) mphocytic_

Leukemia)



Churg-Strauss_Syndrome C34481 C34481 (Churg- C34481 Widespread necrotizing angiitis with

Strauss_Syndrome ) (Churg- granulomas. Pulmonary involvement is

Strauss_Sy frequent. Asthma or other respiratory infection

ndrome ) may precede evidence of vasculitis.

Eosinophilia and lung involvement differentiate

classification C25161 C25161 (classification) C25161 this disease from POLYARTERITIS NODOSA

(classificatio

n)







Clerk C75552 C75552(Clerk C75552 A person employed in an office who performs

syn: Clerical Occupation syn: Clerical (Clerk various tasks such as keeping records or

syn: Clerical Work Occupation syn: Clerical accounts, filing, letter writing, or transcribing.

syn: Clerical Work) Occupation

syn: Clerical

Clinical C25398 C25398 (Clinical ) Work)

C25398 Relating to the examination and treatment of

(Clinical ) patients dependent on direct observation. The

term may also refer to the institution (clinic)

providing this activity.



Clinical Study C15206 C15206 (Clinical Study C15206 Research conducted with human subjects or

) (Clinical on material of human origin in which an

Study ) investigator directly interacts with human

subjects; includes development of new

technologies, mechanism of human diseases,

CML C3174 C3174 (CML) C3174 therapy, clinical trials, epidemiology, behavior

(CML)









collection C25453 C25453 (collection) C25453

(collection)









Colony Forming Unit CFU C68742 C68742 (Colony C68742 A unit of measurement of viable bacterial

Forming Unit ) (Colony numbers. Colony forming unit (CFU) is the

Forming minimum number of separable cells, which is

Unit ) able to produce a visible colony of progeny.

The examples of CFU usage include but not

limited to the measurement of the number of

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Colony-Forming Unit- CFU-GM C63799 C63799 (Colony- C63799 A functional (qualitative) as well as quantitative

Granulocyte Macrophage Assay Forming Unit- (Colony- assay that is utilized as an indicator of

Assay Granulocyte Forming granulopoiesis reconstitution.

Macrophage Assay) Unit-

Granulocyte

combination chemotherapy C191 C191 (combination Macrophag

C191

chemotherapy) (combinatio

n

chemothera

py)

comorbidity C16457 C16457 (comorbidity) C16457

(comorbidity

)







Complement C16459 C16459 (Complement) C16459 The complement system is a complex system

(Compleme of serum proteins that interact in a cascade.

nt) Many of the early components are serine

proteases that activate each other

sequentially. This complement system consists

Complement Component-4 C70618 C70618 (Complement C70618 Complement component-4 (1744 aa,(1) Ab

of three separate activation triggers: ~193

Component-4 ) (Compleme kDa) is part of the complement cascade, which

nt mediates the innate immune response to

Component- infection. The full length protein is a precursor

4) that can is secreted as a trimeric molecule

Complement Hemolytic C70611 C70611 (Complement C70611 containing an alpha, beta and gamma chain.

A screening assay for circulating complement

Activity Assay Hemolytic Activity (Compleme proteins in which diluted serum samples are

Assay ) nt Hemolytic added to antibody-coated erythrocytes and the

Activity percentage of cell lysis is measured. The

Assay ) values are expressed in hemolytic complement

complete remission c4870 c4870 (complete c4870 units per milliliter (CH50), the dilution of serum

remission) (complete

remission)







Complete Response of C70639 C70639 (Complete C70639

Multiple Myeloma or Plasma Response of Multiple (Complete

Cell Leukemia Myeloma or Plasma Response

Cell Leukemia) of Multiple

Myeloma or

Complete_Remission complete C4870 C4870 Plasma Cell The disappearance of all signs of cancer in

C4870

response (Complete_Remission) (Complete_ response to treatment. This does not always

Remission) mean the cancer has been cured.







Concurrent C25456 C25456 (Concurrent ) C25456

(Concurrent

)







confirmed confirmation C25458 C25458 (confirmed) C25458 2900

(confirmed )





NCI|Having been established or verified.

Congenital Abnormality C2849 C2849 (Congenital C2849

Abnormality) (Congenital

Abnormality

)



Congenital_Platelets_Abnorm C61247 C61247 C61247

ality (Congenital_Platelets_ (Congenital

Abnormality) _Platelets_

Abnormality

)

Connective_Tissue_Disorder Connective C26729 C26729 C26729 A heterogeneous group of disorders, some

Tissue (Connective_Tissue_Di (Connective hereditary, others acquired, characterized by

Disease sorder ) _Tissue_Di abnormal structure or function of one or more

sorder ) of the elements of connective tissue, i.e.,

collagen, elastin, or the mucopolysaccharides.

Consolidation Therapy C15679 C15679 (Consolidation C15679 Chemotherapy treatments given after induction

Therapy ) (Consolidati chemotherapy to further reduce the number of

on Therapy cancer cells.

)



Continued Complete C70603 C70603 (Continued C70603

Response Complete Response) (Continued

Complete

Response)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





Conventional Cytogenetics Chromosome C16437 Use this concept for C16437 (Chromosome C16437 The treatment of chromosomes to reveal

Banding conventional Banding) (Chromoso characteristic patterns of horizontal bands.

cytogenetics per Doug me The banding patterns lend each chromosome

Rizzo 8/26/08sc. Banding) a distinctive appearance so the 22 pairs of

human non-sex chromosomes and the X and

CPK C64489 (Creatine (CPK) Y chromosomes can be identified and 2400 413

Kinase Measurement)









Creatine Kinase C64489 C64489 (Creatine C64489

Measurement Kinase Measurement) (Creatine

Kinase

Measureme

nt)

CREST Syndrome C70646 C70646 (CREST C70646

Syndrome) (CREST

Syndrome)







Crohn's Disease C2965 C2965 (Crohn's C2965

Disease) (Crohn's

Disease)







Cryopreservation Cryopreserve C16475 C16475 C16475 Preservation of cells, tissues, organs, or

d (Cryopreservation ) (Cryopreser embryos by storage at low temperatures.

vation )







Culture Procedure C25300 C25300 (Culture C25300 Any laboratory procedure for growing

Procedure ) (Culture microorganisms.

Procedure )







current C25471 C25471 (current) C25471

(current)









cutaneous C13316 C13316 (cutaneous) C13316

(cutaneous)









cutaneous invlovement C39570 C39570 (cutaneous C39570

invlovement) (cutaneous

invlovement

)



Cycle C25472 C25472 (Cycle ) C25472 An event or sequence of events that constitute

(Cycle ) a round or succession of observable

phenomena, recurring usually at regular or

approximately regular time intervals and in the

same sequence.

Cystitis C26738 C26738 (cystitis) C26738 MSH2003_2003_05_12|Inflammation of the 2900

(Cystitis) urinary bladder. (Dorland, 27th ed)









Cytarabine Ara-C C408 Per Doug's request C408 (Cytarabine ) C408 An antimetabolite analogue of cytidine with a 2400 69

please be sure to use (Cytarabine modified sugar moiety (arabinose instead of

the NCI Thesaurus ) ribose). Cytarabine is converted to the

definition triphosphate form within the cell and then

competes with cytidine for incorporation into

Cytogenetic Analysis Cytogenetics, C18280 Use this concept for C18280 (Cytogenetic C18280 DNA. Because the arabinose sugar sterically

Techniques for analysis of chromosomal and

Cytogenetic cytogenetic analysis Analysis ) (Cytogeneti subchromosomal properties and structures,

Technique per Doug Rizzo c Analysis ) such as those to diagnose, classify, screen for,

8/26/08sc. or manage genetic diseases and

abnormalities.

Cytogenetic Remission C18280 (Cytogenetic

Analysis ), C18246 (Cytogeneti

(remission) c

Remission)



cytokine C20464 C20464 (cytokine) C20464 NCI|A class of soluble glycoproteins which act 2100 9

(cytokine) nonenzymatically through specific receptors to

regulate immune responses. Cytokines are

derived from both immune and non-immune

cells and are intercellular mediators that differ

from hormones in that they are produced by a

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





cytomegalovirus CMV C14196 C14196 C14196 NCI|A genus of the family herpesviridae, 2100 431

cytomegalovirus (CMV) (cytomegalo subfamily betaherpesvirinae, infecting the

virus) salivary glands, liver, spleen, lungs, eyes, and

other organs, in which they produce

characteristically enlarged cells with

cytopenia C2979 C2979 (cytopenia) C2979 intranuclear in the number of blood cells.

A reduction inclusions.

(cytopenia)









Daclizumab Anti CD25 C1569 Use NCI-GLOSS C1569 (Daclizumab ) C1569 A monoclonal antibody that is being studied for

Zenepax definition (Daclizuma treatment of adult T-cell leukemia. Also called

Daclizumab b) dacliximab. Monoclonal antibodies are

AntiTAC laboratory-produced substances that can

locate and bind to cancer cells.

Dasatinib C38713 C38713 (Dasatinib) C38713

(Dasatinib)









daunorubicin C62091 C62091 (daunorubicin) C62091 An anthracycline antineoplastic antibiotic with

(daunorubic therapeutic effects similar to those of

in) doxorubicin. Daunorubicin exhibits cytotoxic

activity through topoisomerase-mediated

interaction with DNA, thereby inhibiting DNA

Day C25301 C25301 (Day ) C25301 replication and repair and RNA and protein

The time for Earth to make a complete rotation

(Day ) on its axis; ordinarily divided into twenty-four

hours, equal to 86 400 seconds. This also

refers to a specific day.



Death C28554 C28554 (Death ) C28554 The absence of life or state of being dead.

(Death )









Death Related to Adverse C48275 C48275 (Death C48275 The termination of life associated with an

Event Related to Adverse (Death adverse event.

Event ) Related to

Adverse

Event )

del(12p)/12p- C45577 (Deletion Loss of a genomic DNA sequence. The extent 2011 32

Abnormality ), C13532 (del(12p)/12 of a deletion ranges from the loss of a single

(12p) p-) nucleotide to the loss of a substantial portion of

an entire chromosome. Thus, deletions may

alter the function of a single gene or multiple

del(6q)/6q- C45577 (Deletion genes._Proximal (short) arm of chromosome

(del(6q)/6q- Loss of a genomic DNA sequence. The extent 2011 30

Abnormality ), C13560 ) of a deletion ranges from the loss of a single

(6q) nucleotide to the loss of a substantial portion of

an entire chromosome. Thus, deletions may

alter the function of a single gene or multiple

del(9p)/9p- C45577 (Deletion genes._Distal (long) arm of chromosome 6

(del(9p)/9p- Loss of a genomic DNA sequence. The extent 2011 31

Abnormality ), C13563 ) of a deletion ranges from the loss of a single

(9p ) nucleotide to the loss of a substantial portion of

an entire chromosome. Thus, deletions may

alter the function of a single gene or multiple

Deletion Abnormality C45577 Do not use concept C45577 (Deletion C45577 Loss of a genomic DNA arm of chromosome

genes. _Proximal (short)sequence. The extent

C19296 (Deletion Abnormality ) (Deletion of a deletion ranges from the loss of a single

Mutation) per Doug's Abnormality nucleotide to the loss of a substantial portion of

request ) an entire chromosome. Thus, deletions may

alter the function of a single gene or multiple

Department C42671 C42671 (Department) C42671 genes.

A specialized division of a large organization.

(Departmen

t)







Dermatomyositis C26744 C26744 C26744

(Dermatomyositis) (Dermatom

yositis)







Description C25365 C25365 (Description) C25365 A written or verbal account, representation,

(Description statement, or explanation of something.

)







Destructive Arthritis C70634 C70634 (Destructive C70634

Arthritis) (Destructive

Arthritis)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





Detection C16210 C16210 detection C16210 NCI|The activity of perceiving, discerning, 2100 586

(Detection) discovering or identifying.









Diabetes Mellitus C2985 C2985 (Diabetes C2985

Mellitus) (Diabetes

Mellitus)







diagnosis C15220 C15220 (diagnosis) C15220 NCI|The investigation, analysis and recognition

(diagnosis) of the presence and nature of disease,

condition, or injury from expressed signs and

symptoms; also, the scientific determination of

any kind; the concise results of such an

diagnostic procedure C18020 C18020 diagnostic C18020 investigation. procedures, and tests performed

NCI|Methods, 2100 424

procedure (diagnostic to diagnose disease, disordered function, or

procedure) disability.







Diagnostic, Therapeutic, and C19238 C19238 (Diagnostic, C19238 An object needed to perform a diagnostic,

Research Equipment Therapeutic, and (Diagnostic, therapeutic or research activity.

Research Equipment ) Therapeutic

, and

Research

diffuse C14175 C14175 (diffuse) Equipment ) widely spread; not localized or confined

C14175

(diffuse)









Dimethyl Sulfoxide C437 Be sure to use the C437 (Dimethyl C437 A highly polar organic liquid that is used widely 2006 41

definition specified Sulfoxide ) (Dimethyl as a chemical solvent and a free radical

here. As of 13 March Sulfoxide ) scavenger. It shows a range of

2008, this was the pharmacological activity including analgesia

caDSR definition and and anti-inflammation. Because of its ability to

Disease response C50995 not the NCI Thesaurus C50995 disease C50995 penetrate biological membranes, it is used

NCI-GLOSS|In medicine, an improvement as 2100

response (Disease related to treatment.

response)







diseases and disorders C2991 C2991 (diseases and C2991

disorders) (diseases

and

disorders)



C75521

(Disturbanc

e)

A departure or divergence from that which is

Disturbance C75521 C75521(Disturbance) considered normal.

Down Syndrome Trisomy 21 C2993 C2993 (Down C2993 A chromosomal dysgenesis syndrome

Syndrome Syndrome) (Down resulting from a triplication or translocation of

Syndrome) chromosome 21. Down syndrome occurs in

approximately 1:700 live births. Abnormalities

are variable from individual to individual and

doxorubicin C456 C456 (doxorubicin) C456 An anthracycline antibiotic with retarded

may include mental retardation,antineoplastic

(doxorubicin activity. Doxorubicin, isolated from

) Streptomyces peucetius var. caesius, is the

hydroxylated congener of daunorubicin.

Doxorubicin intercalates between base pairs in

Drug/Toxin-Induced Aplastic C70613 C70613 (Drug/Toxin- C70613 the DNA helix, thereby preventing DNA

Anemia Induced Aplastic (Drug/Toxin-

Anemia) Induced

Aplastic

Anemia)

Drug-Induced Aplastic C35343 C35343 (Drug-Induced C35343

Anemia Aplastic Anemia) (Drug-

Induced

Aplastic

Anemia)

ds DNA C1580 (anti-DNA (ds DNA) 2400 279

antibody)









Electromyography C38056 C38056 C38056

(Electromyography ) (Electromyo

graphy )

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





elevated C25493 C25493 (elevated) C25493

(elevated)









ELISA Enzyme- C16553 C16553 (ELISA ) C16553 An immunoassay utilizing an antibody labeled

linked (ELISA ) with an enzyme marker such as horseradish

Immunosorb peroxidase. While either the enzyme or the

ent Assay antibody is bound to an immunosorbent

substrate, they both retain their biologic

Elutriative Centrifugation Elutriation C18798 C18798 activity; the change in on the activity their

Separation of particlesenzymebasis of as a 2006 67

(Elutriative differential sedimentation rate.|

Centrifugati

on )



Engraftment C37947 C37947 (Engraftment ) C37947

(Engraftme

nt )







Episode C75539 C75539(Episode) C75539 A noteworthy happening that is distinctive in a

(Episode) series of related events.









Erythroblast C12527 Be sure to use the C12527 (Erythroblast) C12527 A nucleated cell in bone marrow from which

definition specified (Erythroblas red blood cells develop.

here. As of 18 March t)

2008, this was the

caDSR definition and

Erythrocyte Red blood C12521 not the NCI Thesaurus C12521 (Erythrocyte ) C12521 Cell specialized for oxygen transport, having a

cell (Erythrocyte high concentration of hemoglobin in the

) cytoplasm and little else; biconcave, anucleate

discs, 7nm diameter in mammals.



Erythropoietin C477 C477 C477 NCI|A recombinant therapeutic agent which is 2100 9

(Recombinant_Erythro (Erythropoie chemically identical to or similar to the

poietin) tin) endogenous glycoprotein erythropoietin (Epo).

Epo promotes the differentiation and

maturation of hematopoietic progenitors into

esophagus C12389 C12389 (esophagus) C12389 erythrocytes; is a mitogen and a

(esophagus

)







established C71155 C71155 established C71155 NCI|Shown to be valid beyond a reasonable 2100

(established doubt.

)







Etanercept Enbrel C2381 C2381 (Etanercept ) C2381 A recombinant soluble dimeric fusion protein 2400 151

(Etanercept consisting of the extracellular ligand-binding

) region of recombinant human tumor necrosis

factor (rhTNF) receptor attached to the

constant (Fc) region of human immunoglobulin

Etiology C16390 C16390 (Etiology) C16390 G (FcIgG). of a disease. moiety of etanercept

The cause The receptor

(Etiology)









etoposide C491 C491 (etoposide) C491 A semisynthetic derivative of podophyllotoxin,

(etoposide) a substance extracted from the mandrake root

Podophyllum peltatum. Possessing potent

antineoplastic properties, etoposide binds to

and inhibits topoisomerase II and its function in

evaluation C25214 C25214 (evaluation) C25214 ligating cleaved DNA molecules, resulting in

Systematic, objective appraisal of the

(evaluation) significance, effectiveness, and impact of

activities or condition according to specified

objectives and criteria.



Evan_Syndrome C61284 C61284 C61284

(Evan_Syndrome ) (Evan_Syn

drome )







ex vivo C70676 C70676 (ex vivo) C70676 Outside the living body; referring to the use or

(ex vivo) positioning of an organ, tissue, or cell in an

environment outside the living organism while

the tissue or cells remain viable.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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Formula





exocrine gland C12712 C12712 (exocrine C12712

gland) (exocrine

gland)







extent C25332 C25332 (extent) C25332

(extent)









Extra-Articular C70636 C70636 (Extra- C70636

Articular) (Extra-

Articular)







Extramedullary C25503 C25503 C25503 Outside of, or unrelated to, any medulla,

(Extramedullary ) (Extramedul especially the medulla oblongata.

lary )







eye C12401 C12401 (eye) C12401

(eye)









Failure C25745 C25745 (failure) C25745 loss of ability to function normally. 2900

(Failure)









Farmer C75559 C75559(Farmer) C75559 A person who produces food by growing plants

(Farmer) or tending animals.









female C16576 C16576 (female) C16576 A person who belongs to the sex that normally

(female) produces ova. The term is used to indicate

biological sex distinctions, or cultural gender

role distinctions, or both. The term

"female_gender" only applies to cultural

Femoral Vein C12716 C12716 (Femoral C12716 distinctions.starts within the inguinal region and

A vein that

Vein) (Femoral extends to the lower extremities.

Vein)







Final C25508 C25508 final C25508 NCI|Conclusive in a process or progression. 2100

(Final)









Finding evidence C3367 C3367 (Finding ) C3367 Objective evidence of disease perceptible to

(Finding ) the examining physician (sign) and subjective

evidence of disease perceived by the patient

(symptom).



First C25509 C25509 (First) C25509 Preceding all others in time or space or

(First) degree.









FLT3 Ligand C20492 C20492 (FLT3 Ligand C20492 Flt3 ligand is a novel hematopoietic growth

) (FLT3 factor ligand for the FLT3 tyrosine kinase

Ligand ) receptor. This growth factor stimulates the

proliferation of hematopoietic progenitor cells.

FLT3 (FLK2) is a tyrosine kinase receptor

Fluorescence in situ FISH C17563 Use this concept for C17563 (Fluorescence C17563 A physical related to CSF1 and KIT. (from

structurallymapping approach that uses

Hybridization FISH per Doug Rizzo in situ Hybridization ) (Fluorescen fluorescent tags to detect hybridization of

8/26/08sc. ce in situ probes within metaphase chromosomes or

Hybridizatio less condensed somatic interphase chromatin.

n) This technique can be used for identification of

Fluorescent Antibody Immunofluore C17370 C17370 (Fluorescent C17370 An immunological techniqueand for gene

chromosomal abnormalities in which the

Technique scence Antibody Technique ) (Fluorescen antibodies are coupled with molecules which

t Antibody fluoresce under ultra violet (UV) light. This

Technique ) makes them particularly suitable for detection

of specific antigens in tissues or on cells.

Fresh C75531 C75531(Fresh) C75531 Not previously used.

(Fresh)

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Formula





Fungi C14209 C14209 (Fungi ) C14209 A kingdom of eukaryotic, heterotrophic

(Fungi ) organisms that live as saprobes or parasites,

including mushrooms, yeasts, smuts, molds,

etc. They reproduce either sexually or

asexually, and have life cycles that range from

gastrointestinal tract C34082 C34082 C34082 simple to complex. Filamentous fungi refer to

(gastrointestinal tract) (gastrointes

tinal tract)







Gemtuzumab Ozogamicin C1806 C1806 (Gemtuzumab C1806 A recombinant, humanized anti-CD33

Ozogamicin ) (Gemtuzum monoclonal antibody attached to the cytotoxic

ab antitumor antibiotic calicheamicin. In this

Ozogamicin conjugate, the antibody binds to and is

) internalized by tumor cells expressing CD33

Gender C17357 C17357 (Gender) C17357 antigen (a sialic acid-dependent glycoprotein

(Gender)









Genetic C17938 C17938 (Genetic) C17938 Inherited; having to do with information that is

(Genetic) passed from parents to offspring through

genes in sperm and egg cells.







grade C48309 C48309 (grade) C48309

(grade)









Graft Transplant C12981 use (NCI-gloss) C12981 (Graft) C12981 NCI-GLOSS|Healthy skin, bone, or other tissue

definition for Graft (Graft) taken from one part of the body and used to

replace diseased or injured tissue removed

from another part of the body.



Graft Versus Host Disease GVHD C3063 C3063 (Graft Versus C3063 NCI|An incompatibility reaction (which may be

Host Disease) (Graft fatal) in a subject (host) of low immunological

Versus Host competence (deficient lymphoid tissue) who

Disease) has been the recipient of immunologically

competent lymphoid tissue from a donor who

Gram per Square Meter Gram per C67282 C67282 (Gram per C67282 lacks at least of areal density defined as a

A metric unit one antigen possessed by the

Meter Square Meter ) (Gram per spread rate at which one gram of a substance

Squared Square is spread over the area of one square meter. It

Meter ) is equal to approximately 0.029 4935 ounce

per square yard. Also used as a dose

Granulocytic Sarcoma C35815 C35815 (Granulocytic C35815 calculation unit to express quantity of an

A tumor mass composed of myeloblasts,agent

Sarcoma ) (Granulocyti neutrophils and neutrophil precursors.

c Sarcoma ) Granulocytic sarcoma is the most common

type of myeloid sarcoma. (WHO, 2001) -- 2003



Greater Than C61584 C61584 (Greater Than C61584 A statement about the relative size or order of

) (Greater two objects specifying that an object of interest

Than ) exceeds another object in quantity or measure

or value or status.



Greater than or Equal to C61583 C61583 (Greater than C61583 NCI|A statement about the relative size or 2100 45

or Equal to) (Greater order of two objects specifying that either both

than or objects are the same in quantity or measure or

Equal to) value or status or that the object of interest

exceeds the other object in one of these ways.

heart disorder C3079 C3079 (heart disorder) C3079

(heart

disorder)







Hematocrit HCT C64796 C64796 (hematocrit) C64796 NCI|A measure of the volume of red blood 2100 53

(Hematocrit cells expressed as a percentage of the total

) blood volume. Normal in males is 43-49%, in

females 37-43%.



Hematologic C62780 C62780 (Hematologic C62780

) (Hematologi

c)







Hematopoietic Stem Cell HSC C12551 C12551 (Hematopoietic c12551

Stem Cell) (Hematopoi

etic Stem

Cell)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Hematopoietic Stem Cell HSCT C12551 (Hematopoietic Primitive blood cells derived from embryonic

Transplantation Stem Cell), C15342 mesenchyme capable of differentiating into any

(Transplantation ) of the blood cell line progenitor cells

(erythroblasts, young granulocytic series cells,

megakaryocytes, etc.)_The replacement of

Hematopoietic_Growth_Facto C20427 C20427 C20427 tissue with tissue from the person's own body

NCI|Endogenous growth factors which 2100 9

r (Hematopoietic_Growth (Hematopoi promote the development of blood cells.

_Factor ) etic_Growth

_Factor)



Hemoglobin C16676 C16676 (hemoglobin) C16676 NCI|The red respiratory protein of erythrocytes, 2100 52

(Hemoglobi consisting of approximately 3.8% heme and

n) 96.2% globin (64.5 KD), which as

oxyhemoglobin (HbO2) transports oxygen from

the lungs to the tissues where the oxygen is

Hemoglobinopathy C3092 C3092 C3092 readily released and HbO2 becomes Hb.

(Hemoglobinopathy ) (Hemoglobi

nopathy )







Hemolytic Uremic Syndrome C75545 C75545(Hemolytic C75545 A form of thrombotic microangiopathy with

Uremic Syndrome) (Hemolytic renal failure, hemolytic anemia, and severe

Uremic thrombocytopenia and purpura

Syndrome)



Hemolytic_Anemia C34376 C34376 C34376

(Hemolytic_Anemia ) (Hemolytic_

Anemia )







Hemorrhage C26791 C26791 (Hemorrhage ) C26791

(Hemorrhag

e)







Hemorrhagic Cyst C75548 C75548(Hemorrhagic C75548 A cyst containing blood.

Cyst) (Hemorrhag

ic Cyst)







Hepatic Disorder C3196 C3196 (Hepatic C3196 NCI|Any disease or dysfunction of the liver and

Disorder) (Hepatic the intrahepatic bile ducts.

Disorder)







Hepatitis C3095 C3095 (Hepatitis) C3095 Inflammation of the liver; usually from a viral

(Hepatitis) infection, but sometimes from toxic agents.







NCI|HSV is a nuclear replicating, icosahedral,

Herpes_Simplex_Virus C14311 C14311 C14311 enveloped DNA virus. The HSV envelope 2100 432

Herpes_Simplex_Virus, (Herpes_Si contains at least 8 glycoproteins. The matrix or

mplex_Viru tegument which contacts both the envelope

s) and the capsid contains at least 15-20

proteins. There are two types of HSV - Type 1

High-grade B-cell lymphoma C6817 C6817 (High-grade B- C6817

cell lymphoma) (High-grade

B-cell

lymphoma)



Histiocytic and Dendritic Cell C9294 C9294 (Histiocytic and C9294

Neoplasms Dendritic Cell (Histiocytic

Neoplasms) and

Dendritic

Cell

history C54625 C54625 (history) Neoplasms)

C54625

(history)









HLA When refering to HLA C20706 (MHC Class I Found on virtually every cell, MHC (Major

in general, combine the Protein-HLA), C20705 Histocompatibility, HLA) Class-I (Antigens)

terms for MHC Class I (MHC Class II Protein ) Proteins consist of noncovalently bound

and II proteins. polymorphic 44-kDa MHC membrane

glycoprotein and nonpolymorphic 12-kDa b2-

HLA Matching HLA Testing , C68707 C68707 (HLA C68707 A process by whichHLA antigens are encoded

microglobulin. The a donor's blood or tissue

HLA Matching) (HLA sample is analyzed to determine its human

Compatibility Matching) leukocyte antigen (HLA) profile so that it can

Testing be transplanted into a patient with the same

profile.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





HLA-A Gene C28585 C28585 (HLA-A Gene) C28585

(HLA-A

Gene)







HLA-B Gene C62778 C62778 (HLA-B Gene) C62778

(HLA-B

Gene)







HLA-C_Gene C62758 C62758 (HLA-C_Gene) C62758

(HLA-

C_Gene)







HLA-DPB1_Gene C29953 C29953 (HLA- C29953

DPB1_Gene) (HLA-

DPB1_Gen

e)



HLA-DQ Antigen C62792 C62792 (HLA-DQ C62792 Polymorphic glycoproteins which are

Antigen ) (HLA-DQ expressed primarily in lymphoid cells and

Antigen ) function to present antigens for CD4+ T

lymphocytes. Certain HLA-DQ protein variants

are associated with susceptibility to insulin-

HLA-DQB1 Gene C70614 C70614 (HLA-DQB1 C70614 dependent diabetes mellitus and several

This gene is involved in the mediation of

Gene ) (HLA-DQB1 antigen presentation.

Gene )







HLA-DR Antigen C16692 C16692 (HLA-DR C16692 |Encoded by multiple HLA-DRA and HLA-DRB

Antigen) (HLA-DR genes in a complex variable 5 cM region of

Antigen) MHC between HLA-B and -D, HLA-DR

Antigens are Class II histocompatibility

transmembrane glycoprotein heterodimers of

HLA-DRB1 Gene C19409 C19409 (HLA-DRB1 C19409 alpha (heavy, 35-kD) and beta (light, 27-kD)

Gene) (HLA-DRB1

Gene)







Hodgkin Lymphoma C9357 C9357 (Hodgkin C9357

Lymphoma) (Hodgkin

Lymphoma)







Homemaker C75560 C75560(Homemaker) C75560 A person who manages a home as their main

(Homemak daily activity.

er)







Hospitalization C25179 C25179 C25179 The condition of being treated as a patient in a

(Hospitalization ) (Hospitaliza hospital.

tion )







Human_Herpesvirus_6 HHV-6 C14218 C14218 C14218 NCI|A human herpesvirus that has been found 2100 433

Human_Herpesvirus_6 (Human_He in certain lymphoproliferative disorders,

rpesvirus_6 replicates in a number of different types of

) leukocytes, and is associated with the

childhood disease roseola (exanthema

Hydroxyurea C560 C560 (Hydroxyurea) C560 subitum).|On-line Medical Dictionary

(Hydroxyure

a)







hypertension C3117 C3117 (hypertension) C3117 Abnormally high blood pressure

(hypertensi

on)







idarubicin C562 C562 (idarubicin) C562 A semisynthetic, 4-demethoxy analogue of the

(idarubicin) anthracycline antineoplastic antibiotic,

daunorubicin. Idarubicin intercalates into DNA

and interferes with the activity of

topoisomerase II, thereby inhibiting DNA

Identical C49034 C49034 (Identical ) C49034 replication, RNA transcription and protein

Exactly alike; incapable of being perceived as

(Identical ) different; being the exact same one; coinciding

exactly when superimposed; having properties

with uniform values along all axes.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Identifier C25364 C25364 (Identifier ) C25364 One or more characters used to identify,

(Identifier ) name, or characterize the nature, properties,

or contents of a thing.







Idiopathic C28242 C28242 (Idiopathic ) C28242 NCI-GLOSS|Describes a disease of unknown

(Idiopathic ) cause.









Idiopathic Pneumonia C62590 C62590(Idiopathic C62590 An inflammatory lung disease characterized by

Syndrome Pneumonia Syndrome) (Idiopathic diffuse interstitial pneumonitis and alveolitis

Pneumonia leading to interstitial fibrosis in the absence of

Syndrome) an identifiable infectious agent.



Idiopathic_Pneumonia_Syndr C62590 C62590 C62590 NCI|An inflammatory lung disease 2100 420

ome Idiopathic_Pneumonia_ (Idiopathic_ characterized by diffuse interstitial pneumonitis

Syndrome Pneumonia and alveolitis leading to interstitial fibrosis in

_Syndrome) the absence of an identifiable infectious agent.



Idiopathic_Thrombocytopenic C3446 C3446 C3446 Thrombocytopenia occurring in the absence of

_Purpura (Idiopathic_Thrombocyt (Idiopathic_ toxic exposure or a disease associated with

openic_Purpura ) Thrombocyt decreased platelets. It is mediated by immune

openic_Pur mechanisms, in most cases

pura ) IMMUNOGLOBULIN G autoantibodies which

imanitib mesylate C1687 C1687 (imanitib C1687 attach to platelets and subsequently undergo

mesylate) (imanitib

mesylate)







Imatinib Mesylate Gleevec C1687 C1687 (Imatinib C1687 The mesylate salt of imatinib, a tyrosine kinase

Mesylate) (Imatinib inhibitor with antiproliferative activity. Imatinib

Mesylate) binds to an intracellular pocket located within

tyrosine kinases (TK), thereby inhibiting ATP

binding and preventing phosphorylation and

Immune_System_and_Relate Immunodefici C27351 C27351 C27351 the subsequent activation of growth receptors

d_Disorders ency and (Immune_System_and (Immune_S

Immunosupp _Related_Disorders ) ystem_and_

ression Related_Dis

Disorders orders )

Immunoglobulin C572 C572 (Immunoglobulin) C572 NCI|Any of the structurally related 2100

(Immunoglo glycoproteins that function as antibodies. They

bulin) are divided into five classes (IGA, IGD, IGE,

IGG, IGM) on the basis of structure and

biological activity.

Immunomagnetic beads combine the concepts C16406 (Cell Techniques and methods for separating cells

for cell sorting and Sorting):C71606 (usually viable) based on a variety of criteria

immunomagnetic (Immunomagnetic for separation, such as size or density, non-

column Column ) specific surface properties, or specific surface

properties. Examples include cell affinity

Inborn_Errors_of_Metabolism Congenital C34816 C34816 C34816 chromatography and centrifugation using

Errors in metabolic processes resulting from

Metabolic (Inborn_Errors_of_Met (Inborn_Err inborn genetic mutations that are inherited or

Disorder abolism) ors_of_Met acquired in utero.

abolism)



Inclusion C25532 C25532 (Inclusion) C25532 The addition of somebody or something to, or

(Inclusion) the presence of somebody or something in, a

group or mixture.







Inconclusive C75569 C75569(Inconclusive) C75569 Not putting an end to doubt or question;

(Inconclusiv leading to no final results or outcome.

e)







Increase C25533 C25533 (Increase) C25533

(Increase)









Ind-2 C38147 C38147 (Ind-2) C38147

(Ind-2)









Infectious Disorder C26726 C26726 (Infectious C26726

Disorder) (Infectious

Disorder)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Inflammation C3137 C3137 (Inflammation) C3137

(Inflammatio

n)







Inflammatory Bowel Disease C3138 C3138 (Inflammatory C3138

Bowel Disease) (Inflammato

ry Bowel

Disease)



Infliximab Remicade C1789 C1789 (Infliximab ) C1789 A recombinant chimeric, mouse-human 2400 152

(Infliximab ) monoclonal antibody directed against tumor

necrosis factor alpha (TNF-alpha), a protein

involved in inflammation, cell survival, and

apoptosis. Infliximab may be pro- apoptotic or

Infusion Procedure Infusion C15388 C15388 (Infusion C15388 anti-apoptotic, depending on cell type. (NCI04)

A method of putting fluids, including drugs, into

Procedure ) (Infusion the bloodstream. Also called intravenous

Procedure ) infusion.







Inpatient C25182 C25182 (Inpatient ) C25182 A patient who is residing in the hospital where

(Inpatient ) he is being treated.









Institution C41206 C41206 (Institution) C41206 An established society, corporation, foundation

(Institution) or other organization founded and united for a

specific purpose, e.g. for health-related

research; also used to refer to a building or

buildings occupied or used by such

Integer C45255 C45255 (Integer ) C45255 organization. no fractional part, including the

A number with

(Integer ) negative and positive numbers as well as zero.









intensity C25539 C25539 (intensity) C25539

(intensity)









Intent C25725 C25725 (Intent) C25725 An anticipated outcome that is the meaning or

(Intent) purpose for actions taken, thus guiding your

planned actions.







interferon C2049 C2049 (interferon) C2049

(interferon)









Internal Jugular Vein C32849 C32849 (Internal C32849

Jugular Vein ) (Internal

Jugular

Vein )



International Staging System C70657 C70657 (International C70657 A method of staging myeloma published by the

for Myeloma Staging System for (Internation International Myeloma Working Group in 2003.

Myeloma) al Staging

System for

Myeloma)

Intracranial_Hemorrhage C50438 C50438 C50438 FDA|Bleeding within the cranium, which may 2900

(Intracranial_Hemorrha (Intracranial be extradural, subdural, subarachnoid, or

ge) _Hemorrha cerebral.

ge )



Intrathecal Chemotherapy C15750 C15750 (Intrathecal C15750

Chemotherapy) (Intrathecal

Chemother

apy)



Intrathecal Route of C38267 C38267 (Intrathecal C38267 Administration of drugs directly into spinal

Administration Route of Administration (Intrathecal subarachnoid space in the cerebrospinal fluid,

) Route of at any level of the cerebrospinal axis, including

Administrati injection into the cerebral ventricles, in order to

on ) bypass the blood-brain barrier and achieve

Intravenous Route of IV C38276 C38276 (Intravenous C38276 Administration of a on the meninges or vein or

local, rapid effects drug within or into a

Administration Route of Administration (Intravenou veins. Introduction of the drug directly into

) s Route of venous circulation results in 100%

Administrati bioavailability due to an absence of the

on ) absorption phase, provides a precise and

continuous mode of drug therapy, especially

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





invasive C14159 C14159 (invasive) C14159

(invasive)









isolation C25549 C25549 isolation C25549 NCI|A state of separation; the act of isolating 2100 429

(isolation) something; setting something apart from

others; marked by separation of or from usually

contiguous elements.



ISS Stage I Plasma Cell C70658 C70658 (ISS Stage I C70658 Plasma cell myeloma with beta-2-microglobulin

Myeloma Plasma Cell Myeloma) (ISS Stage I less than 3.5 and albumin greater than or

Plasma Cell equal to 3.5 (median survival of 62 months).

Myeloma) Note that the older Durie/Salmon staging

system defines stage I quite differently. (PDQ)

ISS Stage II Plasma Cell C70659 C70659 (ISS Stage II C70659 Plasma cell myeloma with beta-2-microglobulin

Myeloma Plasma Cell Myeloma) (ISS Stage less than 3.5 and albumin less than 3.5 or beta-

II Plasma 2-microglobulin 3.5 to less than 5.5 (median

Cell survival of 44 months). Note that the older

Myeloma) Durie/Salmon staging system defines stage II

ISS Stage III Plasma Cell C70660 C70660 (ISS Stage III C70660 quite differently. (PDQ)

Plasma cell myeloma with beta-2-microglobulin

Myeloma Plasma Cell Myeloma) (ISS Stage greater than or equal to 5.5 (median survival of

III Plasma 29 months). Note that the older Durie/Salmon

Cell staging system defines stage III quite

Myeloma) differently. (PDQ)

juvenile myelomonocytic C9233 C9233 (juvenile C9233

leukemia (JMML) myelomonocytic (juvenile

leukemia (JMML)) myelomono

cytic

leukemia

Juvenile_Myelomonocytic_Le C9233 C9233 (JMML))

C9233

ukemia (Juvenile_Myelomonoc (Juvenile_M

ytic_Leukemia ) yelomonocy

tic_Leukemi

a)

Karnofsky Performance C28013 C28013 (Karnofsky C28013 A standard way of measuring the ability of

Status Performance Status ) (Karnofsky cancer patients to perform ordinary tasks. The

Performanc scores range from 0 to 100, with a higher

e Status ) score indicating a better ability to carry out

daily activities. KPS may be used to determine

Lab Lupus Inhibitor C70648 C70648 (Lab Lupus C70648 a patient's prognosis, to measure changes in

Inhibitor) (Lab Lupus

Inhibitor)







Laboratory Finding C38470 C38470 (Laboratory C38470 The result of a lab test to measure an attribute

Finding ) (Laboratory or to determine the presence, absence or

Finding ) degree of a condition.







laboratory procedure C25294 C25294 (laboratory C25294 A medical procedure that involves testing a

procedure) (laboratory sample of blood, urine, or other substance

procedure) from the body. Tests can help determine a

diagnosis, plan treatment, check to see if

treatment is working, or monitor the disease

Laborer C75556 C75556(Laborer) C75556 over time. who works with their hands;

Someone

(Laborer) someone engaged in manual labor.









Lansky Play-Performance C38144 C38144 (Lansky Play- C38144 The play-performance scale for children is a

Status Performance Status ) (Lansky parent-rated instrument which records usual

Play- play activity as the index of performance. It is

Performanc similar to the Karnofsky Performance Scale for

e Status ) adults.

last C25551 C25551 last C25551 2100 420

(last)





NCI|Coming after all others in time or space or degree or being the only one remaining.

lenalidomide C2668 C2668 (lenalidomide) C2668

(lenalidomid

e)







Less Than or Equal To C61586 C61586 (Less Than or C61586 A statement about the relative size or order of

Equal To ) (Less Than two objects specifying that either both objects

or Equal To are the same in quantity or measure or value

) or status or that the object of interest is smaller

than the other object in one of these ways.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Less_than C61585 C61585 (less than) C61585 NCI|A statement about the relative size or

(Less_than) order of two objects specifying that an object of

interest is smaller than another object in

quantity or measure or value or status.



Leukapheresis C15269 C15269 leukapheresis C15269 NCI-GLOSS|Removal of the blood to collect 2100

(Leukapher specific blood cells; the remaining blood is

esis) returned to the body.







leukemia C3161 C3161 (leukemia) C3161

(leukemia)









Leukocyte White blood C12529 C12529 (Leukocyte ) C12529 Blood cells that are devoid of hemoglobin,

cell (Leukocyte capable of ameboid motion and fagocytosis,

) and act as the principal components of the

immune system.



Level C2554 C2554 (Level) C2554 Degree

(Level)









Life C37987 C37987 (Life ) C37987 The organic phenomenon that distinguishes

(Life ) living organisms from nonliving ones; showing

characteristics of life.







Life Threatening or Disabling C41337 C41337 (Life C41337 Any adverse event that places the patient, in

Adverse Event Threatening or (Life the view of the initial reporter, at immediate risk

Disabling Adverse Threatening of death from the adverse event as it occurred,

Event ) or Disabling i.e., it does not include an adverse experience

Adverse that, had it occurred in a more severe form,

local C67263 C67263 (local ) Event )

C67263 Of or belonging to adeath.

might have caused restricted area or locality

(local )









local therapy C15687 C15687 (local therapy) C15687

(local

therapy)







Lung C12468 C12468 (Lung) C12468

(Lung)









Lung Carcinoma Lung Cancer C4878 C4878 (Lung C4878 A carcinoma originating in the lung. Lung

Carcinoma ) (Lung carcinomas usually arise from the epithelium

Carcinoma ) that lines the bronchial tree (bronchogenic

carcinomas), and are classified as small cell or

non-small cell carcinomas. Non-small cell lung

Lung Disorder C3198 C3198 (Lung Disorder) C3198 carcinomas are usually adenocarcinomas,

(Lung

Disorder)







Lung_Tissue Lung C33024 C33024 (Lung_Tissue) C33024 Tissue consisting of an external serous coat,

Parenchyma (Lung_Tiss subserous areolar tissue and lung

ue) parenchyma. The parenchyma is made up of

lobules wound together by connective tissue. A

primary lobule consists of a terminal

Lupus Anticoagulant Antibody C70620 C70620 (Lupus C70620 bronchiole, respiratory bronchioles, and

Anticoagulant Antibody) (Lupus

Anticoagula

nt Antibody)



lymphoma C3208 C3208 (lymphoma) C3208

(lymphoma)









lymphoplasmacytic C3212 C3212 C3212

lymphoma/Waldenstrom (lymphoplasmacytic (lymphoplas

macroglobulinemia lymphoma/Waldenstro macytic

m macroglobulinemia) lymphoma/

Waldenstro

m

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Maculopapular Lesion C75579 A skin condition consisting of both macules

(Maculopap and papules.

ular Lesion)

C75579(Maculopapular

C75579 Lesion)

Maintenance Therapy C15688 C15688 (Maintenance C15688 Treatment that is given to help a primary

Therapy ) (Maintenan (original) treatment keep working. Maintenance

ce Therapy therapy is often given to help keep cancer in

) remission.



male C20197 C20197 (male) C20197 A person who belongs to the sex that normally

(male) produces sperm. The term is used to indicate

biological sex distinctions, cultural gender role

distinctions, or both. The term "male_gender"

only applies to cultural distinctions.

Malignant C14143 C14343 (malignant) C14143 NCI|Refers to abnormal cell activity manifested 2900

(Malignant ) by decreased control over growth and function,

causing tumor growth or spread into

surrounding tissue and adverse effects to the

host.

Malignant Neoplasm Cancer C9305 C9305 (Malignant C9305 A tumor composed of atypical neoplastic, often

Neoplasm ) (Malignant pleomorphic cells that invade other tissues.

Neoplasm ) Malignant neoplasms often metastasize to

distant anatomic sites and may recur after

excision. The most common malignant

manipulation C48310 C48310 (manipulation) c48310 neoplasms are carcinomas (adenocarcinomas

(manipulatio

n)







Match C54116 C54116 (Match ) C54116 An exact duplicate; coinciding in

(Match ) characteristics; similar or consistent.









means C47955 C47955 (means) C47955

(means)









Medication C459 C459 (Medication ) C459 A drug or medicine that treats or prevents or

(Medication alleviates the symptoms of disease.

)







Metaphase C16846 C16846 (Metaphase ) C16846 The second phase of mitosis, in which the

(Metaphase chromosomes line up across the equatorial

) plane of the spindle prior to separation.







metastasis C19151 C19151 (metastasis) C19151

(metastasis)









Method C71460 C71460 (Method) C71460 A means, manner of procedure, or systematic

(Method) course of actions that have to be performed in

order to accomplish a particular goal.







MHC Class I Protein-HLA C20706 C20706 (MHC Class I C20706 Found on virtually every cell, MHC (Major

Protein-HLA) (MHC Class Histocompatibility, HLA) Class-I (Antigens)

I Protein- Proteins consist of noncovalently bound

HLA) polymorphic 44-kDa MHC membrane

glycoprotein and nonpolymorphic 12-kDa b2-

MHC Class II Protein_ HLA C20705 C20705 (MHC Class II C20705 MHC Class-II The HLA antigens are encoded

microglobulin.Proteins are non-covalently

Protein ) (MHC Class linked polymorphic alpha/beta transmembrane

II Protein_ glycoproteins. The immunological function of

HLA) MHC Class-II proteins is to bind and present

antigenic peptides on the surfaces of cells for

Microscopic Polyarteritis C70549 C70549 (Microscopic C70549 recognition by the antigen-specific T typically

A systemic necrotizing vasculitis that cell

Polyarteritis) (Microscopi affects the small and medium-sized muscular

c arteries. In some cases, however, microscopic

Polyarteritis vessels are also affected (e.g., in the kidneys),

) a condition that has been called microscopic

Microscopic Polyarteritis C70549 C70549 (Microscopic C70549 polyarteritis or polyangiitis; this disorder is felt

Polyarteritis) (Microscopi

c

Polyarteritis

)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Mikulicz_Disease Sicca C34819 C34819 C34819 A chronic, benign, and usually painless

Syndrome (Mikulicz_Disease) (Mikulicz_Di inflammatory swelling of the lacrimal and

sease) salivary glands. It is considered by some to

include the glandular enlargement associated

with other diseases, such as Sjogren's

Mild C70666 C70666 (Mild) C70666 syndrome, sarcoidosis, lupus erythematosus,

(Mild)









mismatch C67078 C67078 (mismatch) c67078

(mismatch)









Missing Value Reason C48655 C48655 (Missing C48655 A specific reason explaining why a meaningful

Value Reason ) (Missing value is not available. A meaningful value

Value answers the question posed by a Data

Reason ) Element Concept. In contrast, a Missing Value

Reason answers the implicit question "Why is

Mitoxantrone C62050 C62050 (Mitoxantrone C62050 there no 'meaningful' value?", with

An anthracenedione antibiotic when there is

) (Mitoxantro antineoplastic activity. Mitoxantrone

ne ) intercalates into and crosslinks DNA, thereby

disrupting DNA and RNA replication. This

agent also binds to topoisomerase II, resulting

mixed C25259 C25259 mixed C25259 NCI|Involving or composed of different DNA

in DNA strand breaks and inhibition of kinds. 2100

(mixed)









Mobilized Peripheral Blood C75576 C75576(Mobilized C75576 Blood stem cells found in the circulation after

Stem Cell Peripheral Blood Stem (Mobilized being stimulated to leave the bone marrow,

Cell) Peripheral usually by treatment with a cytokine or other

Blood Stem drug.

Cell)

Moderate C61376 C61376 (Moderate) C61376

(Moderate)









Molecular Analysis Molecular C19770 C19770 (Molecular C19770 Techniques for studying or analyzing the

Technique, Analysis ) (Molecular genetic composition and mechanisms of living

molecular Analysis ) organisms at the molecular level. May refer to

marker the understanding and manipulation of genes

(DNA).

Molecular Remission C19770 (Molecular (Molecular

Analysis ), C18246 Remission)

(remission)







Molecular_Genetic_Abnormal C36391 C36391 C36391

ity (Molecular_Genetic_Ab (Molecular_

normality ) Genetic_Ab

normality )



Monoclonal Antibody C20401 C20401 (Monoclonal C20401 An antibody produced by a clone or genetically

Antibody ) (Monoclonal homogenous fast-growing cells i.e., hybridoma.

Antibody ) Hybridoma cells are cloned to establish cell

lines producing a specific antibody that is

chemically and immunologically homogeneous.

mononeuritis multiplex C70938 C70938 (mononeuritis C70938 They are widely used in cancer detection,

multiplex) (mononeurit

is multiplex)







Mononucleated Blood Cell C73123 Added to EVS on 18 C73123 C73123 A mixture of cells possessing a single nucleus, 2006 145

March 2008 (Mononucleated Blood (Mononucle including monocytes and lymphocytes; blood

Cell ) ated Blood leukocytes from which granulocytes have been

Cell ) separated and removed.



Monosomy 17 C36509 C36509 (Monosomy C36509

17) (Monosomy

17)







Monosomy 5 C36523 C36523 (Monosomy 5) C36523

(Monosomy

5)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Monosomy 7 C36411 C36411 (Monosomy 7) C36411 A chromosomal abnormality consisting of the 2011 14

(Monosomy absence of one of the copies of chromosome 7

7) in somatic cells.







Monosomy X C36630 C36630 (Monosomy X) C36630 no definition

(Monosomy

X)







multiple C17648 C17648 (multiple) C17648 NCI|Having, relating to, or consisting of more

(multiple) than one individual, element, part, or other

component; manifold. (dictionary.com)







Multiple Myeloma-IgA C70606 C70606 (Multiple C70606

Myeloma-IgA) (Multiple

Myeloma-

IgA)



Multiple Myeloma-IgD C70607 C70607 (Multiple C70607

Myeloma-IgD) (Multiple

Myeloma-

IgD)



Multiple Myeloma-IgE C70608 C70608 (Multiple C70608

Myeloma-IgE) (Multiple

Myeloma-

IgE)









Multiple Myeloma-IgG C70609 C70609 (Multiple C70609

Myeloma-IgG) (Multiple

Myeloma-

IgG)



Multiple Myeloma-IgM (not C70610 C70610 (Multiple C70610

Waldenstrom Myeloma-IgM (not (Multiple

Macroglobulinemia) Waldenstrom Myeloma-

Macroglobulinemia)) IgM (not

Waldenstro

Multiple Myeloma-Light Chain C70605 C70605 (Multiple m

C70605

Only Myeloma-Light Chain (Multiple

Only) Myeloma-

Light Chain

Only)

multiple sclerosis C3243 C3243 (multiple C3243

sclerosis) (multiple

sclerosis)







Multiple Sclerosis C3243 C3243 (Multiple C3243

Sclerosis) (Multiple

Sclerosis)







muromonab-CD3 OKT-3 C1321 C1321 A murine IgG2a monoclonal antibody with 2006 83

(muromona potential immunosuppressive activity.

b-CD3) Muromonab-CD3 specifically targets and binds

to the T-cell receptor CD3 complex on the

surface of circulating T-lymphocytes, which

Muscle Contracture C75585 C75585(Muscle C75585 mediates antigen recognition process. a result

Permanent contraction of a muscle as Binding

Contracture) (Muscle of spasm or paralysis.

Contracture

)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Mutation C16885 C16885 (Mutation ) C16885 Permanent, transmissible changes in the

(Mutation ) genetic material of an organism. Mutations can

range from a single base change to the loss of

a significant portion of a chromosome. These

occur when DNA is not repaired prior to

Myasthenia_Gravis C60989 C60989 C60989 replication. Mutations in germ cells can be

(Myasthenia_Gravis) (Myasthenia

_Gravis)







Myeloablative Chemotherapy C16231 Do not use the concept C16231 (Myeloablative C16231 The administration of high-dose 2400 113

C1711 (Myeloablative Chemotherapy ) (Myeloablati chemotherapy, with or without total body

Agonist ) ve irradiation, to eradicate the underlying disease

Chemother and/or ablate the immune system of the

apy ) patient.

Myelodysplastic Syndrome C3247 C3247 C3247 A clonal hematopoietic disorder characterized

(Myelodysplastic (Myelodyspl by dysplasia and ineffective hematopoiesis in

Syndrome ) astic one or more of the hematopoietic cell lines.

Syndrome ) The dysplasia may be accompanied by an

increase in myeloblasts, but the number is less

Myelodysplastic_myeloprolifer C27262 C27262 C27262 than 20%, which, according to the WHO

ative disease (MDS) (Myelodysplastic_myelo (Myelodyspl

proliferative disease astic_myelo

(MDS)) proliferative

disease

Myelodysplastic_Syndrome C3247 C3247 (MDS))

C3247

(Myelodysplastic_Syndr (Myelodyspl

ome ) astic_Syndr

ome )



Myeloperoxidase C71145 C71145 C71145 Myeloperoxidase (745 aa, ~84 kDa) is

(Myeloperoxidase ) (Myelopero encoded by the human MPO gene. This

xidase ) protein is involved in innate host defense by

facilitating the oxygen-dependent mechanism

of apoptosis.

Name C42614 C42614 (Name) C42614 The words or language units by which a thing

(Name) is known.









Necrotizing Vasculitis C70635 C70635 (Necrotizing C70635

Vasculitis) (Necrotizing

Vasculitis)







Negative Selection C70599 C70599 (Negative C70599

Selection) (Negative

Selection)







Neoadjuvant Therapy Induction C15665 C15665 (Neoadjuvant C15665 Treatment given before the primary treatment.

Therapy Therapy ) (Neoadjuva Examples of neoadjuvant therapy include

nt Therapy ) chemotherapy, radiation therapy, and hormone

therapy.



CD56 C25276 C25276 C25276 NCI|Neural Cell Adhesion Molecule is a 2100 76

Antigen (Neural Cell Adhesion (Neural membrane-bound glycoprotein member of the

Molecule) Cell Ig superfamily that binds to a variety of other

Neural Cell Adhesion Adhesion cell adhesion proteins involved in diverse

Molecule Molecule) contact-mediated interactions. NCAM appears

Next Subsequent C53286 C53286 (Next) C53286 Subsequent; immediately following in timein the

on early embryonic cells and is important or

(Next) order.









nilotinib C48375 C48375 (nilotinib) C48375

(nilotinib)









Nodular Partial Remission C70633 C70633 (Nodular C70633

Partial Remission) (Nodular

Partial

Remission)



Non Hodgkin's Lymphoma C3211 C3211 (Non Hodgkin's C3211

Lymphoma) (Non

Hodgkin's

Lymphoma)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Non-Neoplastic Heart C3079 C3079 (Non-Neoplastic C3079 (Non-

Disorder Heart Disorder) Neoplastic

Heart

Disorder)



Non-Secretory Myeloma C4734 C4734 (Non-Secretory C4734 (Non-

Myeloma) Secretory

Myeloma)







normal C14165 C14165 (normal) C14165

(normal)









not Negation, C25594 C25594 (not) C25594 An operation in which a term denies or inverts

non- (not) the meaning of another term or construction.









Not Applicable C48660 C48660 (Not C48660 Determination of a value is not relevant in the

Applicable ) (Not current context.

Applicable )







Not Identified C48661 C48661 (not identified) C48661 NCI|The finding is not present, but a value of 2900

(Not 'none' cannot be unequivocally established

Identified) absence in the current context.







not otherwise specified C19594 C19594 (not otherwise C19594 NCI|Not characterized in any other way.

specified) (not

otherwise

specified)



Nucleated Blood Cell C73126 Added to EVS on 18 C73126 (Nucleated C73126 The cellular material of blood consisting of 2006 144

March 2010 Blood Cell ) (Nucleated white blood cells and nucleated red blood cells.

Blood Cell )







Nucleated Red Blood Cell C73125 Added to EVS on 18 C73125 (Nucleated C73125 Red blood cells that are at the last stage of 2006 146

March 2009 Red Blood Cell ) (Nucleated development, still containing a nucleus, that

Red Blood are found in the bone marrow and occasionally

Cell ) in the peripheral blood.



number C25337 C25337 (number) C25337

(number)









obesity C3283 C3283 (obesity) C3283

(obesity)









Obesity C3283 C3283 (Obesity) C3283

(Obesity)









occurrence C25275 C25275 (occurrence) C25275 An instance of something happening, such as

(occurrence an event or incident.

)







Onset C25279 C25279 (Onset ) C25279 The start, beginning, or early stages.

(Onset )









Open Lung Biopsy C51923 C51923 C51923 NCI|Removal of tissue from the lung, for 2100 425

Open_Lung_Biopsy (Open Lung microscopic examination, obtained during an

Biopsy ) open surgical procedure.







Oral Route of Administration C38288 C38288 (Oral Route of C38288 The introduction of a substance to the mouth

Administration ) (Oral Route or into the gastrointestinal tract by the way of

of the mouth, usually for systemic action. It is the

Administrati most common, convenient, and usually the

on ) safest and least expensive route of drug

administration, but it uses the most

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Organ C13018 C13018 (organ) C13018 NCI|A unique macroscopic (gross) anatomic 2900

(Organ) structure that performs specific functions. It is

composed of various tissues. An organ is part

of an anatomic system or a body region.

Representative examples include the heart,

Organism C14250 C14250 (Organism) C14250 lung, liver, spleen, andan animal, a plant, a

A living thing, such as uterus.

(Organism) bacterium, or a fungus.









Organizational Unit Organization C41167 C41167 C41167 Organizational unit like a laboratory, institute or

(Organizational Unit ) (Organizatio consortium.

nal Unit )







osteopetrosis C26840 C26840 (osteopetrosis) C26840

(osteopetro

sis)







other C17649 C17649 (other) c17649

(other)









Overlap_Necrotizing_Arteritis C61282 C61282 C61282

(Overlap_Necrotizing_ (Overlap_N

Arteritis ) ecrotizing_

Arteritis )



p-ANCA IFA C17370 (Fluorescent (p-ANCA 2400 454

Antibody Technique ), IFA)

C71145

(Myeloperoxidase ),

C16295 (antibody)

p-ANCA Positive C17998 (Unknown), (p-ANCA 2400 469

C25294 (laboratory Positive)

procedure), C71145

(Myeloperoxidase ),

C16295 (antibody)

Parainfluenza Virus C75532 C75532(Parainfluenza C75532 Any of several paramyxoviruses (genus

Virus) (Parainfluen Respirovirus and Rubulavirus) that are a

za Virus) frequent cause of infections of the lower

respiratory tract.



Paraproteinemia C27468 C27468 C27468 A plasma cell disorder in which an abnormal

(Paraproteinemia) (Paraprotei amount of a single immunoglobulin is present

nemia) in the serum. Paraproteinemias may be seen

in conjunction with various carcinomas, chronic

inflammatory and infectious conditions, and

Part Time Employment C75562 C75562(Part Time C75562 other diseases

Employment involving less than the standard

Employment) (Part Time or customary working time.

Employmen

t)



Partial Remission Partial C18058 C18058 (Partial C18058 A decrease in the size of a tumor, or in the

Response Remission) (Partial extent of cancer in the body, in response to

Remission) treatment.







Partial Response of Multiple C70641 C70641 (Partial C70641

Myeloma or Plasma Cell Response of Multiple (Partial

Leukemia Myeloma or Plasma Response

Cell Leukemia) of Multiple

Myeloma or

Pathology C18189 C18189 (Pathology) Plasma Cell NCI|The medical science, and specialty

C18189 2100 568

(Pathology) practice, concerned with all aspects of disease,

but with special reference to the essential

nature, causes, and development of abnormal

conditions, as well as the structural and

Patient C16960 C16960 (Patient ) C16960 functional changes that result from the disease

A person who receives medical attention, care,

(Patient ) or treatment, or who is registered with medical

professional or institution with the purpose to

receive medical care when necessary.



Pediatric Childhood C39299 C39299 (Pediatric ) C39299 NCI-GLOSS|(pee-dee-AT-rik) Having to do

(Pediatric ) with children.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





pending C53470 C53470 (pending) C53470 NCI|Not yet decided or settled; awaiting 2900

(pending) conclusion or confirmation.|Dictionary.com









Peptic Ulcer C3318 C3318 (Peptic Ulcer) C3318

(Peptic

Ulcer)







Per C65039 C65039 (Per ) C65039

(Per )









Percentage C25613 C25613 (Percentage) C25613 A fraction or ratio with 100 understood as the

(Percentag denominator.

e)







Performance Status C20641 C20641 (Performance C20641 A measure of how well a patient is able to

Status ) (Performan perform ordinary tasks and carry out daily

ce Status ) activities.







Performed C38000 C38000 (Performed) C38000 Executed and carried through to completion.

(Performed)









Peripheral_Nervous_System C12465 C12465 C12465 That part of the nervous system consisting of

(Peripheral_Nervous_S (Peripheral_ the nerves and neurons that reside or extend

ystem) Nervous_S outside the central nervous system.

ystem)



Ph -/BCR-ABL- C70629 C70629 (Ph -/BCR- C70629 (Ph

ABL-) -/BCR-ABL-

)







Ph Unknown/BCR- C70627 C70627 (Ph C70627 (Ph

Unknown/BCR-) Unknown/B

CR-)







Ph Unknown/BCR Unknown C70628 C70628 (Ph C70628 (Ph

Unknown/BCR Unknown/B

Unknown) CR

Unknown)



Ph Unknown/BCR+ C70623 C70623 (Ph C70623 (Ph

Unknown/BCR+) Unknown/B

CR+)







Ph-/BCR Unknown C70630 C70630 (Ph-/BCR C70630 (Ph-

Unknown) /BCR

Unknown)







Ph-/BCR+ C70602 C70602 (Ph-/BCR+) C70602 (Ph-

/BCR+)









Ph+/BCR Unknown C70624 C70624 (Ph+/BCR C70624

Unknown) (Ph+/BCR

Unknown)







Pharmacological_Treatment C15986 C15986 C15986 Treatment of disease through the use of drugs.

(Pharmacological_Trea (Pharmacol

tment) ogical_Trea

tment)



C1909 C1909 NCI|An active natural, synthetic or semi- 2100

(Pharmalogi synthetic ingredient including endogenous

C1909 c_Substanc body substance that is intended to furnish

(Pharmalogic_Substan e) pharmacological activity or other direct effect in

Pharmalogic_Substance ce) the diagnosis, cure, mitigation, treatment, or 33

prevention of disease or to affect the structure

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





phase C25257 C25257 (phase) C25257

(phase)









Philadelphia Chromosome C28452 C28452 (Philadelphia C28452

Chromosome) (Philadelphi

a

Chromoso

me)

philadelphia chromosome C9128 C9128 (philadelphia C9128

positive CM chromosome positive (philadelphi

CM) a

chromosom

e positive

Planned C25619 C25619 (Planned) CM)

C25619 To devise, contrive, or formed in design.

(Planned)









plasma cell C12486 C12486 (plasma cell) C12486

(plasma

cell)







Plasma Cell Myeloma C3242 C3242 (Plasma Cell C3242 NCI|A bone marrow-based plasma cell

Myeloma ) (Plasma neoplasm characterized by a serum

Cell monoclonal protein and skeletal destruction

Myeloma ) with osteolytic lesions, pathological fractures,

bone pain, hypercalcemia, and anemia.

platelet C12520 C12520 (platelet) C12520 Clinical variants include non-secretory

(platelet)









Platelet count C51951 C51951 (platelet count) C51951 NCI|The determination of the number of

(Platelet platelets in a blood sample, usually expressed

count) as platelets per cubic millimeter (cmm) of

whole blood.



platelet count 20000 C53266 C53266 (platelet count C53266 NCI|Indicates a platelet count of at least 2100 45

20000) (platelet 20,000 per cubic millimeter.

count

20000)



platelet count 50000 C53267 C53267 (platelet count C53267 2100 46

50000) (platelet

count

50000) NCI|Indicates a platelet count of at least 50,000

per cubic millimeter.

Platelet Transfusion C15366 C15366(Platelet C15366 The infusion of platelets into the bloodstream.

Transfusion) (Platelet

Transfusion

)



Polymyositis C26925 C26925 (Polymyositis ) C26925

(Polymyositi

s)







Positive Selection C71257 C71257 (Positive C71257 The separation of specific cells or cell

Selection ) (Positive populations from a heterogeneous mixture.

Selection ) Specifically it refers to the selective retention of

a population of desired cells through

recognition of cells bearing the specified

post C38008 C38008 (post) C38008 characteristics. following a point or another

The time period

(post) period of time.









preparative regimen C61155 C61155 (preparative C61155 The chemotherapy and/or radiation given to

regimen) (preparative bone marrow transplant patients prior to

regimen) transplant to kill diseased cells and/or make

space for healthy new marrow and/or suppress

the immune system so graft rejection does not

Present In C25626 C25626 (Present) C25626 occur.

Being or existing in a specified place or at the

(Present) specified time.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Preventative Intervention C15843 C15843 (Preventative C15843

Intervention) (Preventativ

e

Intervention

)

Previous C25627 C25627 (Previous) C25627 Occurring prior to something else.

(Previous)









Primary C25251 C25251 (Primary) C25251

(Primary)









Primary Induction Failure C70622 C70622 (Primary C70622

Induction Failure) (Primary

Induction

Failure)



Primary Refractory (Less than C70604 C70604 (Primary C70604

Partial Response (PR) to Refractory (Less than (Primary

Initial Therapy) / Primary Partial Response (PR) Refractory

Induction Failure-Resistant to Initial Therapy) / (Less than

(PIF Res) Primary Induction Partial

prior pre C25629 C25629 (prior) (PIF

Failure-Resistant Response

c25629

(prior)







NCI|Earlier in time or order._NCI|A tumor

Prior Malignancy History of C25629, C25629 (Prior), C9305 composed of atypical neoplastic, often

Malignancy C9305 (Malignant Neoplasm) pleomorphic cells that invade other tissues.

Malignant neoplasms often metastasize to distant

anatomic sites and may recur after excision. The

most common malignant neoplasms are

carcinomas (adenocarcinomas or squamous cell

Processing Processing C48177 C48177 (Processing ) C48177 The act of preparing or putting through a

Technique (Processing prescribed procedure.

)







Professional Occupation C75558 C75558(Professional C75558 An occupation requiring special education,

Occupation) (Profession especially in the liberal arts or sciences.

al

Occupation)



Progression of Multiple C70643 C70643 (Progression C70643

Myeloma or Plasma Cell of Multiple Myeloma or (Progressio

Leukemia Plasma Cell Leukemia) n of Multiple

Myeloma or

Plasma Cell

Progressive Disease C35571 Leukemia)

C35571 (Progressive C35571

Disease) (Progressiv

e Disease)







Propidium Iodide C72903 Added to EVS on 13 C72903 ( Propidium C72903 A fluorescent nucleic acid dye which binds only 2006 152

March 2012 Iodide ) (Propidium to double-stranded nucleic acids. It has a

Iodide ) molecular weight of 668.4, an absorbance

maximum of 535nm, and an emission

maximum of 617 nm. It is commonly used to

Proteinase-3 C17548 C17548 (Proteinase-3) C17548 Encoded by human content of a cell or to

determine the DNA PRTN3 Gene (Peptidase

(Proteinase- S1 Family), 256-aa 29-kD Proteinase 3

3) precursor is coordinately expressed with and

packed in neutrophilic azurophil granules with

ELA2 and AZU during myeloid development.

protocol C42651 C42651 (protocol) C42651 A rule which neutral serine activity should be

An antibiotic guides how anprotease, PRTN3

(protocol) performed.









Protozoal Infection C34953 C34953 (Protozoal C34953 MSH2003_2003_05_12|Infections with 2900

Infection) (Protozoal unicellular organisms of the subkingdom

Infection) PROTOZOA.







Proximal C25236 C25236 (Proximal ) C25236 NCI-GLOSS|In medicine, refers to a part of the

(Proximal ) body that is closer to the center of the body

than another part. For example, the knee is

proximal to the toes. The opposite is distal.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Psoriasis C3346 C3346 (Psoriasis ) C3346

(Psoriasis )









Psoriatic_Arthritis C61277 C61277 C61277

(Psoriatic_Arthritis ) (Psoriatic_A

rthritis )







Psychiatric Disorder C2893 C2893 (Psychiatric C2893

Disorder) (Psychiatric

Disorder)







Pulmonary C13304 C13304 (Pulmonary) C13304

(Pulmonary)









Pulmonary hypertension C3120 C3120 (Pulmonary C3120 Increased pressure within the pulmonary

hypertension) (Pulmonary circulation, usually secondary to cardiac or

hypertensio pulmonary disease

n)



Pulmonary_Fibrosis C26869 C26869 C26869 Chronic inflammation and progressive fibrosis

(Pulmonary_Fibrosis) (Pulmonary of the pulmonary alveolar walls, with steadily

_Fibrosis) progressive dyspnea, resulting finally in death

from oxygen lack or right heart failure.



Purpose C25634 C25634 (Purpose ) C25634 What something is used for; reason or

(Purpose ) intention.









radiation therapy C1533 C1533 (radiation C1533

therapy) (radiation

therapy)







Radiography C38101 C38101(Radiography) C38101 A radiographic procedure using the emission

(Radiograp of x-rays to form an image of the structure

hy) penetrated by the radiation.







Radiolabeled C18138 C18138 (Radiolabeled C18138 Any compound that has been joined with a

) (Radiolabel radioactive substance.

ed )







Reaction C25637 C25637 (Reaction) C25637 Reaction; a bodily process occurring due to the

(Reaction) effect of some foregoing stimulus or agent.









reason C25638 C25638 (reason) C25638 2900

(reason)



NCI|An explanation of the cause of some

phenomenon or action.

recipient C53268 C53268 (recipient) C53268

(recipient)









Recombinant Granulocyte- GM-CSF C1288 C1288 (Recombinant C1288 NCI|A recombinant therapeutic agent which is 2100 9

Macrophage Colony- Granulocyte- (Recombina chemically identical to or similar to the

Stimulating Factor Macrophage Colony- nt endogenous glycoprotein cytokine growth

Stimulating Factor ) Granulocyte- factor granulocyte-macrophage colony

Macrophag stimulating factor (GM-CSF). Therapeutic GM-

Recombinant Human Palifermin, C2455 C2455 (Recombinant e Colony-

C2455 NCI|A recombinant formexpansion and

CSF induces the clonal of the endogenous 2100 9

Keratinocyte Growth Factor Kepivance, Human Keratinocyte (Recombina human keratinocyte growth factor with cell

KGF Growth Factor) nt Human growth promoting activity. Palifermin acts in the

Keratinocyt manner similar to the endogenous keratinocyte

e Growth growth factor that binds to keratinocyte growth

Recombinant_Granulocyte_C G-CSF C1287 C1287 Factor)

C1287 factor recombinant therapeutic agent which in

NCI|A receptors on the epithelial cell surfaceis 2100 9

olony_Stimulating_Factor Recombinant_Granuloc (Recombina chemically identical to or similar to the

yte_Colony_Stimulating nt_Granuloc endogenous cytokine granulocyte colony-

_Factor yte_Colony stimulating factor (G-CSF). Secreted by

_Stimulatin monocytes, macrophages and neutrophils and

g_Factor) other cells after activation, G-CSF stimulates

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





recovery C25746 C25746 (recovery) C25746 NCI|A healing process and/or an outcome 2100 45

(recovery) implying relative health. The term is typically

used in the context of direct and indirect effects

of sickness or injury.



Recurrent C14173 C14173 (Recurrent) C14173

(Recurrent)









Recurrent_Disease relapse C38155 C38155 C38155 The return of a disease after a period of

(Recurrent_Disease) (Recurrent_ remission.

Disease)







reduced reduction C25640 C25640 (reduced) C25640

(reduced)









registry C61393 C61393 (registry) C61393

(registry)









Relapse from Complete C70645 C70645 (Relapse from C70645

Response of Multiple Complete Response of (Relapse

Myeloma or Plasma Cell Multiple Myeloma or from

Leukemia Plasma Cell Leukemia) Complete

Response

Related Relationship C25648 C25648 (Related) of Multiple

C25648 A state of connectedness between people,

(Related) objects, or events; to be associated or

connected with something.







Relative C21480 C21480 (Relative ) C21480 A person related by blood or marriage.

(Relative )









remission C18246 C18246 (remission) C18246

(remission)









Remove C64914 C64914 (Remove ) C64914 Shift the position or location of; take out of.

(Remove )









renal C25225 C25225 (renal) C25225 Of or pertaining to the kidney.

(renal)









Renal Disorder C3149 C3149 (Renal C3149

Disorder) (Renal

Disorder)







Renal failure C4376 C4376 (Renal failure) C4376 NCI|Acute or chronic condition, characterized 2900

(Renal by the inability of the kidneys to adequately

failure) filter the blood substances, resulting in uremia

and electrolyte imbalances. Acute renal failure

is usually associated with oliguria or anuria,

Report C25375 C25375 (Report) C25375 hyperkalemia, and pulmonary edema. Chronic

A short textual account; having provided a

(Report) short account.









Representation C67045 C67045 C67045 NCI|An activity that stands as an equivalent of

(Representation) (Represent something or results in an equivalent; typical

ation) of, or the same as, others in a larger group of

people or things.



Research C15319 C15319 (Research) C15319 Systematic investigation into a subject in order

(Research) to discover facts, to establish or revise a

theory, or to develop a plan of action based on

the facts discovered.

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Respiratory_Syncytial_Virus RSV C14267 C14267 RSV C14267 NCI-GLOSS|A virus that causes respiratory 2100 435

(Respiratory infections with cold-like symptoms.

_Syncytial_

Virus )



Response_Evaluation_Criteri RECIST C49164 C49164 C49164 Standard parameters to be used when

a_in_Solid_Tumors (Response_Evaluation (Response_ documenting response of solid tumors to

_Criteria_in_Solid_Tum Evaluation_ treatment; a set of published rules that define

ors ) Criteria_in_ when cancer patients improve ("respond"),

Solid_Tumo stay the same ("stable"), or worsen

Rheumatoid_Arthritis C2884 C2884 rs )

C2884 ("progression") during treatments. (from

(Rheumatoid_Arthritis ) (Rheumatoi

d_Arthritis )







Rheumatologic Disorder C27204 C27204 C27204

(Rheumatologic (Rheumatol

Disorder) ogic

Disorder)



rituximab C1702 C1702 (rituximab) C1702

(rituximab)









Route of Administration C38114 C38114 (Route of C38114 Designation of the part of the body through

Administration ) (Route of which or into which, or the way in which, the

Administrati medicinal product is intended to be introduced.

on ) In some cases a medicinal product can be

intended for more than one route and/or

Salesperson C75553 C75553(Salesperson C75553 method ofemployed to sell goods or services

A person administration.|ICH

syn: Selling Occupation syn: Selling (Salesperso especially to customers in a store or to

Occupation) n customers that are visited within a geographic

syn: Selling area.

Occupation)

Same C64637 Be sure to use the C64637 (Same ) C64637 Equal, or closely similar or comparable, in kind

definition specified (Same ) or quality or quantity or degree.

here. As of 13 March

2008, this was the

caDSR definition and

Same C64637 not the NCI Thesaurus C64637 (Same ) C64637

(Same )









C75527

(Schirmer

C75527(Schirmer Test Test

Schirmer Test Wetting Wetting Wetting An indication of the amount of moisture

Synonym: Wetting C75527 Synonym: Wetting) Synonym: collected on a filter paper strip in 5 minutes.

Scl 70 Positive C16516 Wetting)

(Scl 70

(Topoisomerase I), Positive)

C16295 (antibody)







Second C25666 C25666 (Second) C25666 Coming next after the first in position in space

(Second) or time or degree or magnitude.









Secondary C25667 C25667 (Secondary) C25667

(Secondary)









Sedimentation C54178 Do not use conept C54178 C54178 The act or process of settling particles by 2006 51

C559 (Hetastarch) (Sedimentation ) (Sedimentat mechanical means from a state of suspension

ion ) in air or water.







Serological C41264 C41264 (Serological) C41264

(Serological

)







serositis C70428 C70428 (serositis) C70428 Inflammation of a serous membrane.

(serositis)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Serum C13325 C13325 (Serum) C13325 The clear portion of the blood that remains

(Serum) after the removal of the blood cells and the

clotting proteins.







Severe C70667 C70667 (Severe) C70667

(Severe)









Severe Aplastic Anemia C61229 C61229 (Severe C61229

Aplastic Anemia) (Severe

Aplastic

Anemia)



Severe Combined C61238 C61238 (Severe C61238

Immunodeficiency with Combined (Severe

Absence of T and B Cells Immunodeficiency with Combined

Absence of T and B Immunodefi

Cells ) ciency with

Severe Combined C61239 C61239 (Severe C61239 of

Absence

Immunodeficiency with Combined (Severe

Absence of T, Normal B Cells Combined

Immunodeficiency with

Absence of T, NormalImmunodefi

B Cells ) ciency with

Severe_Combined_Immunod SCID C3472 C3472 Absence

C3472 of X-linked or autosomal recessive disorder

eficiency (Severe_Combined_Im (Severe_Co characterized by defects of both humoral and

munodeficiency ) mbined_Im cell mediated immunity, resulting in low or

munodeficie absent antibody levels, leukopenia, marked

ncy ) susceptibility to infections, and early death.--

Sheep Red Blood Cell C72897 Added to EVS on 13 C72897 (Sheep Red C72897 A technique for identifying and removing T 2006 68

Rosetting March 2010 Blood Cell Rosetting) (Sheep Red lymphocytes based on their ability to form

Blood Cell rosettes with untreated sheep erythrocytes.

Rosetting)



Sibling C25204 C25204 (Sibling ) C25204 A person's brother or sister.

(Sibling )









Sicca Syndrome C70647 C70647 (Sicca C70647

Syndrome) (Sicca

Syndrome)







Significant C41130 C41130 (Significant ) C41130 A term applied to differences, correlations,

(Significant cause-and-effect relationships, etc., to indicate

) that they are noticeable, probably too closely

correlated to be attributed to chance and

therefore indicating a systematic relation:

Sjogren_s_Syndrome C26883 C26883 C26883 substantial, fairly large; also having

Chronic inflammatory and autoimmune

(Sjogren_s_Syndrome (Sjogren_s_ disease in which the salivary and lacrimal

) Syndrome ) glands undergo progressive destruction by

lymphocytes and plasma cells resulting in

decreased production of saliva and tears. The

Skilled Worker C75554 C75554(Skilled C75554 A worker who has called sicca syndrome,

primary form, oftenacquired special skills.

Worker) (Skilled

Worker)







skin C12470 C12470 (skin) C12470

(skin)









Skin Rash C39594 C39594 (Skin Rash) C39594

(Skin Rash)









Slit-lamp Examination C75583 C75583(Slit-lamp C75583 Examination of the anterior segment of the eye

Examination) (Slit-lamp using a medical instrument called a slit lamp.

Examinatio

n)



Solid Tumor C9292 C9292 (Solid Tumor) C9292

(Solid

Tumor)

Concept Synonym CUI Note Concantenation Concanten Definition Form Question

Values Only ation Number

Formula





Source C25683 C25683 (Source) C25683

(Source)









Soybean Lectin Agglutination C72902 Added to EVS on 13 C72902 (Soybean C72902 A technique for removing T lymphocytes based 2006 63

March 2011 Lectin Agglutination ) (Soybean on differential agglutination with soybean lectin.

Lectin

Agglutinatio

n)

specified C38024 C38024 (specified) C38024

(specified)









specify C25685 C25685 (specify) C25685

(specify)









Specimen C19157 C19157 (Specimen) C19157 Specimen; a bit of tissue or blood or urine that

(Specimen) is taken or used for research purposes.









Stable C30103 C30103 stable C30103 NCI|Stable; subject to little fluctuation; showing 2100

(Stable) little if any change.









Stable Disease C18213 C18213 (Stable C18213 Cancer that is neither decreasing nor

Disease) (Stable increasing in extent or severity.

Disease)







Stable Multiple Myeloma or C70642 C70642 (Stable C70642

Plasma Cell Leukemia Multiple Myeloma or (Stable

Plasma Cell Leukemia) Multiple

Myeloma or

Plasma Cell

stage C16899 C16899 (stage) Leukemia) The extent of a cancer within the body,

C16899

(stage) especially whether the disease has spread

from the original site to other parts of the body.







status C25688 C25688 (status) C25688

(status)









Stem_Cell_Mobilization_Ther C62604 C62604 SC C62604 NCI|Therapy to cause release of stem cells 2100

apy mobilization therapy (Stem_Cell from the bone marrow into the peripheral blood

_Mobilizatio circulation for the purpose of leukapheresis,

n_Therapy ) prior to stem cell transplantion. Hematopoietic

growth factors or chemotherapeutic agents

Stills disease C61278 C61278 (Stills disease) C61278 often are used to stimulate the mobilization.

(Stills

disease)







Stringent Complete C70637 C70637 (Stringent C70637

Response (sCR) of Multiple Complete Response (Stringent

Myeloma or Plasma Cell (sCR) of Multiple Complete

Leukemia Myeloma or Plasma Response

Cell Leukemia) (sCR) of

Student C75561 C75561(Student) Multiple

C75561 A person who is enrolled in an educational

(Student) institution.









Subclavian Vein C12794 C12794 (Subclavian C12794 The continuation of the axillary vein which

Vein ) (Subclavian follows the subclavian artery and then joins the

Vein ) internal jugular vein to form the

brachiocephalic vein.



Submission Submitted C25695 C25695 (Submission) C25695 Referred for judgment or consideration;

(Submissio handed over.

n)

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Formula





subtype C25696 C25696 (subtype) C25696

(subtype)









Suicide C3394 C3394 NCI|The act of ending one's own life. 2900

(Suicide)









Susceptibility Predispositio C16505 C16505 (Susceptibility C16505 The constitutional or inborn state disposing to

n ) (Susceptibili a disease, group of diseases, or metabolic or

ty ) structural anomaly.







swelling C3399 C3399 (swelling) C3399

(swelling)









Syndrome C28193 C28193 (Syndrome) C28193 A set of symptoms or conditions that occur

(Syndrome) together and suggest the presence of a certain

disease or an increased chance of developing

the disease.



systemic C13310 C13310 (systemic) C13310 Affecting an entire system.

(systemic)









Systemic sclerosis This is the way that C13310 (systemic), (Systemic Affecting an entire system._chronic hardening

Doug wants the term C26746 (scleroderma) sclerosis) and thickening of the skin caused by swelling

curated. For and thickening of fibrous tissue leading to

scleroderma be sure to eventual atrophy of the epidermis; can occur

use the specified as a localized or a systemic disease.

Systemic Therapy C15698 definition. In the NCI C15698 (Systemic C15698 (sis-TEM-ik THER-a-pee) Treatment using

Therapy ) (Systemic substances that travel through the

Therapy ) bloodstream, reaching and affecting cells all

over the body.



Systemic_Lupus_Erythemato SLE C3201 C3201 C3201 A chronic inflammatory connective tissue

sus (Systemic_Lupus_Eryth (Systemic_ disease marked by skin rashes, joint pain and

ematosus ) Lupus_Eryt swelling, inflammation of the kidneys,

hematosus inflammation of the fibrous tissue surrounding

) the heart (i.e., the pericardium), as well as

t(1;19)(q23;p13.3) C27715 C27715 C27715 A chromosomal Not all affected individuals

other problems. abnormality consisting of the 2011 19

(t(1;19)(q23;p13.3)) (t(1;19)(q23 translocation of 19p13.3 with 1q23, resulting in

;p13.3) ) the fusion of the TCF3 (E2A) gene with the

PBX1 gene.



t(10;14)(q24;q11) C36352 C36352 C36352 A chromosomal abnormality consisting of the 2011 25

(t(10;14)(q24;q11) ) (t(10;14)(q2 translocation of 10q24 with 14q11, leading to

4;q11) ) inappropriate and abundant expression of

HOX11 protein in T cells bearing the

translocation.

t(4;11)(q21;q23) C36365 C36365 C36365 A chromosomal abnormality consisting of the 2011 20

(t(4;11)(q21;q23)) (t(4;11)(q21 translocation of 4q21 with 11q23.

;q23))







t(5;17)(q32;q12) C36362 C36362 C36362 A chromosomal abnormality consisting of the 2011 21

(t(5;17)(q32;q12) ) (t(5;17)(q32 translocation of 5q32 with 17q12.

;q12) )







t(8;14)(q24;q11) C39347 C39347 C39347 A chromosomal abnormality consisting of the 2011 22

(t(8;14)(q24;q11) ) (t(8;14)(q24 translocation of 8q24 with 14q11, which

;q11) ) juxtaposes the c-MYC gene with the gene for

the T cell receptor alpha chain resulting in

overexpression of c-MYC in T cells bearing the

t(V;11)(v;q23) C38375 C38375 (t(V;11)(v;q23) C38375 translocation.

A chromosomal abnormality consisting of the 2011 27

) (t(V;11)(v;q translocation of genetic material from any one

23) ) of several chromosomes to the 11q23 region,

resulting in an MLL gene rearrangement.



T-Cell Antigen CD7 CD7, anti C38935 C38935 (T-Cell Antigen C38935 (T- Expressed in thymocytes and mature T cells by 2006 79

CD7 antibody CD7 ) Cell Antigen human CD7 Gene (Immunoglobulin

CD7 ) Superfamily), 240-aa 25-kDa (precursor) T-

Cell Antigen CD7 is a cell surface type I

transmembrane glycoprotein that interacts with

SECTM1, contains an Ig-like domain, and is

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T-Cell Chronic Lymphocytic C70649 C70649 (T-Cell Chronic C70649 (T-

Leukemia Lymphocytic Leukemia) Cell Chronic

Lymphocyti

c Leukemia)



T-Cell Depletion Therapy T-Cell C15699 C15699 (T-Cell C15699 (T- NCI-GLOSS|Treatment to destroy T cells,

Depletion Depletion) Cell which play an important role in the immune

Depletion) response. Elimination of T cells from a bone

marrow graft from a donor may reduce the

chance of an immune reaction against the

T-Cell Differentiation Antigen C73129 Added to EVS on 18 C73129 (T-Cell recipient's tissues.

C73129 (T- T-cell differentiation antigen CD6 (668 aa, ~72 2006 78

CD6 March 2012 Differentiation Antigen Cell kDa) is encoded by the human CD6 gene. This

CD6 ) Differentiati protein plays a role in the adherence of

on Antigen immature thymus cells to thymic epithelial cells.

CD6 )

T-Cell Receptor, Alpha-Beta TCR C17433 C17433 (T-Cell C17433 (T- T-cell receptors composed of CD3-associated

Receptor, Alpha-Beta ) Cell alpha and beta polypeptide chains and

Receptor, expressed primarily in CD4+ or CD8+ T-cells.

Alpha-Beta Unlike immunoglobulins, the alpha-beta T-cell

) receptors recognize antigens only when

T-Cell Surface Glycoprotein C73124 Added to EVS on 18 C73124 (T-Cell presented in glycoprotein CD5 (495

C73124 (T- T-cell surfaceassociation with major aa, ~54 2006 77

CD5 March 2011 Surface Glycoprotein Cell Surface kDa) is encoded by the human CD5 gene. This

CD5 ) Glycoprotei protein may be involved in regulating the

n CD5 ) proliferation of T-cells.



T-Cell_Non- C3466 C3466 (T-Cell_Non- C3466 (T-

Hodgkin_s_Lymphoma Hodgkin_s_Lymphoma Cell_Non-

) Hodgkin_s_

Lymphoma

)

Technique C16847 C16847 (Technique) C16847 A practiced and regimented skill or series of

(Technique) actions.









Temporal_Arteritis Giant Cell C35065 C35065 C35065 A systemic autoimmune vasculitis occurring

Arteritis (Temporal_Arteritis ) (Temporal_ primarily in people over the age of 50.

Arteritis ) Pathologic features include a necrotizing

panarteritis including granulomas and giant

cells. There is a predilection for involvement of

Tenderness C75540 C75540(Tenderness) C75540 central nervous system blood vessels and the

Discomfort elicited through touch or pressure.

(Tendernes

s)







Test_Result C36292 C36292 (Test_Result ) C36292

(Test_Resul

t)







thalidomide C1702 C1702 (thalidomide) C1702

(thalidomide

)







Thaw C48165 C48165 (Thaw) C48165 The process whereby heat changes something

(Thaw) from a solid to a liquid.









Therapeutic Procedure C49236 C49236 (Therapeutic C49236

Procedure) (Therapeuti

c

Procedure)



Therapy Related Malignant C4969 C4969 (Therapy C4969 The development of a malignant neoplasm in

Neoplasm Related Malignant (Therapy response to medical or surgical treatment,

Neoplasm ) Related induced by the treatment itself.

Malignant

Neoplasm )

Therapy-Related AML C8252 C8252 (Therapy- C8252 An acute myeloid leukemia arising as a result

Related AML) (Therapy- of the mutagenic effect of alkylating agents

Related and/or ionizing radiation. (WHO, 2001)

AML)



Thioguanine C876 C876 (Thioguanine ) C876 A synthetic guanosine analogue

(Thioguanin antimetabolite. Phosphorylated by

e) hypoxanthine-guanine

phosphoribosyltransferase, thioguanine

incorporates into DNA and RNA, resulting in

inhibition of DNA and RNA syntheses and cell

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Formula





Thrombocytopenic Purpura C26870 C26870 C26870 NCI|Purpura associated with a reduction in 2900

(Thrombocytopenic (Thrombocy circulating blood platelets which can result from

Purpura) topenic a variety of factors.

Purpura)



Thromboembolism C28195 C28195 C28195 MSH2003_2003_05_12|Obstruction of a 2900

(Thromboembolism) (Thromboe vessel by a blood clot that has been

mbolism) transported from a distant site by the blood

stream.



Thrombosis C26891 C26891 (Thrombosis ) C26891

(Thrombosi

s)







Time C25207 C25207 (Time) C25207

(Time)









Timepoint C68568 C68568 (Timepoint ) C68568 A specific point in the time continuum,

(Timepoint ) including those established relative to an

event.







Tissue Donor Donor C25168 C25168 (donor) C25168 Someone who gives blood or tissue or an

(donor) organ to be used in another person.









T-Lymphocyte C12476 C12476 (T- C12476 (T-

Lymphocyte) Lymphocyte

)







T-Lymphocyte C12476 C12476 (T- C12476 (T-

Lymphocyte) Lymphocyte

)







Tolerance Induction Pre-Solid C70612 C70612 (Tolerance C70612

Organ Transplant Induction Pre-Solid (Tolerance

Organ Transplant) Induction

Pre-Solid

Organ

Topoisomerase I C16516 C16516 Transplant) Encoded by human TOP1 Gene (TOPI

C16516

(Topoisomerase I) (Topoisome Family), 765-aa 90.7-kD monomeric DNA

rase I) Topoisomerase I catalyzes transient ATP-

independent breaking/rejoining of DNA and

controls DNA topology during transcription.

Topoisomerase_II_Inhibitor- C27755 C27755 C27755 DNA topoisomerases I and II relax negative

Related_Acute_Myeloid_Leuk (Topoisomerase_II_Inhi (Topoisome

emia bitor- rase_II_Inhi

Related_Acute_Myeloid bitor-

_Leukemia) Related_Ac

Topoisomerase-II Inhibitor C1968 C1968 ute_Myeloid Substances that either stabilize DNA-protein

C1968

(Topoisomerase-II (Topoisome complexes damaging DNA (e g., teniposide),

Inhibitor ) rase-II or those that inhibit the catalytic activity of the

Inhibitor ) enzyme (e.g., merbarone, ICRF-187). Despite

their differences in action, these agents all

Topotecan Hydrochloride C2828 C2828 (Topotecan C2828 block cells in G2/M

The hydrochloride salt of the semisynthetic

Hydrochloride ) (Topotecan camptothecin analog topotecan with

Hydrochlori antineoplastic activity. During the S phase of

de ) the cell cycle, topotecan selectively stabilizes

topoisomerase I-DNA covalent complexes,

Total C25304 C25304 (Total) C25304 thereby inhibiting religation whole, also

Pertaining to an entirety or of topoisomerase I-

(Total) constituting the full quantity or extent;

complete; derived by addition.







Total Complement C70611 (Complement (Total 2400 382

Hemolytic Activity Complemen

Assay ) t)







Total Complement Assay C70617 C70617 (Total C70617

Complement Assay) (Total

Complemen

t Assay)

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Toxicity C27990 C27990 (Toxicity) C27990 The finding of bodily harm due to the

(Toxicity) poisonous effects of something.









Toxoplasma C75538 C75538(Toxoplasma) C75538 A genus of protozoa that is parasitic in

(Toxoplasm humans, other mammals, and some birds.

a)







Transbronchial_Lung_Biopsy C51749 C51749 C51749 2100

Transbronchial_Lung_ (Transbronc

Biopsy hial_Lung_

Biopsy) NCI|Removal of tissue through the bronchial

wall, for microscopic examination.

Translocation C25756 C25756 (Translocation C25756 The movement of a physical object from one

) (Translocati place to another.

on )







Translocation 12p C25756 (Translocation The movement of a physical object from one 2011 29

), C13532 (12p) (Translocati place to another._Proximal (short) arm of

on 12p) chromosome 12







Translocation 9p C25756 (Translocation The movement of a physical object from one 2011 24

), C13563 (9p ) (Translocati place to another._Proximal (short) arm of

on 9p) chromosome 9







Transplant (Graft) Graft C12981 C12981 (Graft) C12981 Healthy skin, bone, or other tissue taken from

(Transplant) one part of the body and used to replace

diseased or injured tissue removed from

another part of the body.

Transplantation C15342 C15342 C15342 The replacement of tissue with tissue from the

(Transplantation ) (Transplant person's own body or from another person.

ation )







Treatment Regimen Treatment C15697 C15697 (Treatment C15697 A treatment plan that specifies the dosage, the

Protocol Regimen ) (Treatment schedule, and the duration of treatment.

Regimen )

Trisomy 11 C37191 C37191 (Trisomy 11) C37191

(Trisomy

11)







Trisomy 13 C36529 C36529 (Trisomy 13) C36529

(Trisomy

13)







Trisomy 17 C37865 C37865 (Trisomy 17 ) C37865 A chromosomal abnormality consisting of the 2011 17

(Trisomy 17 presence of a third copy of chromosome 17 in

) somatic cells.







Trisomy 21 C43224 C43224 (Trisomy 21) C43224 A chromosomal abnormality consisting of the 2011 18

(Trisomy presence of a third copy of chromosome 21 in

21) somatic cells.







Trisomy 4 C36530 C36530 (Trisomy 4) C36530 A chromosomal abnormality consisting of the 2011 16

(Trisomy 4) presence of a third copy of chromosome 4 in

somatic cells.







Trisomy 8 C36396 C36396 (Trisomy 8) C36396 A chromosomal abnormality consisting of the 2011 15

(Trisomy 8) presence of a third copy of chromosome 8 in

somatic cells.







Trypan Blue C910 C910 (Trypan Blue ) C910 An acid azo dye commonly used as a stain to

(Trypan distinguish viable from non-viable cells. It turns

Blue ) dead cells blue and viable cells unstained. It is

a known animal carcinogen and an

experimental teratogen.

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Trypan Blue Benzamine C910 C910 (Trypan Blue ) C910 An acid azo dye commonly used as a stain to

Blue, (Trypan distinguish viable from non-viable cells. It turns

Visionblue Blue ) dead cells blue and viable cells unstained. It is

a known animal carcinogen and an

experimental teratogen.

Tumor Purging C70600 C70600 (Tumor C70600

Purging) (Tumor

Purging)







type C25284 C25284 (type) C25284

(type)









ulcerative colitis C2952 C2952 (ulcerative C2952

colitis) (ulcerative

colitis)







Umbilical Cord Blood C13300 Use alternate definition C13300 (Umbilical C13300 Blood from the placenta (afterbirth) that

Cord Blood ) (Umbilical contains high concentrations of stem cells

Cord Blood needed to produce new blood cells.

)



Unemployment C75563 C75563(Unemploymen C75563 The state of not having a job.

t) (Unemploy

ment)







Unique Identifier C70663 C70663 (Unique C70663 A set of characters used as a code that is

Identifier ) (Unique unique in the context or the system for which it

Identifier ) is created. It serves as a means of

identification and reference (often instead of a

name) for an entity, person, thing, function,

Unit C44278 C44278 (Unit ) C44278 procedure, activity, variable, or body of data.

A single undivided thing occurring in the

(Unit ) composition of something else.









unit of measure performance C20641 C25709 (unit of C25709 NCI|A measure of how well a patient is able to

status measure) (unit of perform ordinary tasks and carry out daily

measure) activities.







Unknown C17998 C17998 (Unknown) C17998 NCI|Not known, not observed, not recorded, or

(Unknown) refused.









unrelated C25328 C25328 (unrelated) C25328

(unrelated)









Upper_Respiratory_System C33839 C33839 C33839

(Upper_Respiratory_Sy (Upper_Res

stem) piratory_Sy

stem)



Valvular Heart Disorder C45525 C45525 (Valvular Heart C45525

Disorder) (Valvular

Heart

Disorder)



Vascular C13311 C13311 (vascular) C13311 Relating to or containing blood vessels 2900

(Vascular)









vasculitis C26912 C26912 (vasculitis) C26912

(vasculitis)









velafermin C48425 C48425 (velafermin) C48425

(velafermin)

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Verified C45513 C45513 (Verified) C45513

(Verified)









Very Good Partial Response C70638 C70638 (Very Good C70638

(VGPR) of Multiple Myeloma Partial Response (Very Good

or Plasma Cell Leukemia (VGPR) of Multiple Partial

Myeloma or Plasma Response

Cell Leukemia) (VGPR) of

Viable C25324 C25324 (Viable) Multiple

C25324 Capable of life or normal growth and

(Viable) development.









Video- VATS C63704 C63704 VATS, C63704 NCI|Endoscopic surgery of the pleural cavity 2100 425

assisted_Thoracic_Surgery (Video- performed with visualization via video

assisted_Th transmission.

oracic_Surg

ery)

viral C27985 C27985 (viral) C27985 Having to do with a virus 2900

(viral)









viral infection C3439 C3439 (viral infection) C3439 (viral NCI|Any disease caused by a virus. 2900

infection)









Volume C25335 C25335 (Volume ) C25335 The amount of three dimensional space

(Volume ) occupied by an object or the capacity of a

space or container.







whole blood C41067 C41067 whole blood C41067 NCI|Blood that has not been separated into its 2100

(whole various components; blood that has not been

blood) modified except for the addition of an

anticoagulant.



without C25718 C25718 (without) C25718

(without)









Yes C49488 C49488 (Yes) C49488 The affirmative response to a question.

(Yes)









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Concept Synonym CUI Note Concantenation Concanten Definition Form Question

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