Canine Heartworm Disease Effects and Treatments

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					Canine Heartworm Disease:
  Effects and Treatments
           Traci Smith
Eastern Connecticut State University
    Clinical and laboratory
observations in 91 dogs infected
  with Dirofilaria immitis in
       northern Greece

  Z.S. Polizopoulou, A. F. Koutinas, M. N.
   Saridomichelakis, M. N. Patsikas, L. S.
   Leontidis, N. A. Roubies, A. K. Desiris
                Background
•   Caused by parasite Dirofilaria immitis
•   Transmitted by mosquitoes
•   Prevalent in warmer weather
•   Prevention is available
•   Treatment is successful
              Three types:
• Type I- asymptomatic
• Type II- mild to moderate clinical signs
• Type III- right congestive heart failure
                 Symptoms
•   Exercise intolerance
•   Chronic cough
•   Weight loss
•   Decreased appetite
•   Congestive heart failure
•   Lethargy
          Reasons for the Study
•   To find the most efficient type of treatment
•   To determine the best method of detection
•   To see the long term effects of the disease
•   To see how well subjects recovered
            Methods of Study
• Studied dogs ages 1 to 11 years
• Examined medical records of 91 dogs infected
  with heartworm
• Two types of tests were ran for the detection of
  heartworm
• Parasitological test
• Immunological test
• X-rays were taken to detect damage to the heart
• 71 dogs were treated
               Treatment
• Sodium thiacetarsamide (Caparsolate)
  intavenously twice daily
• Melarsomine hydrochloride (Immiticide)
  intramuscularly twice daily
• All were given oral ivermectin for 4 weeks
               Treatment Results
40
35
30
25
20                                 Caparsolate
15                                 Immiticide

10
5
0
     # Treated Recovery   Deaths
 Stages of Heartworm and
   Occurrence of Death
50
45
40
35
30
                           Type 1
25
                           Type 2
20
                           Type 3
15
10
 5
 0
     # Infected   Deaths
                Summary

• No differences were found in terms of drug
  efficacy or complication rate
• Both detection tests were equally accurate
• Some dogs treated with Caparsolate suffered
  kidney damage
• Six fatalities occurred out of 71
• Only 4 dogs had lasting effects on physical
  performance
Questions?

				
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posted:12/4/2011
language:English
pages:12