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					Endoh et al. Supplement for Table 5                       ProbUniqueVirus


                                                                                                               -3
                                                                                             Probabilities (x 10 )
                                                                              Sequence    Non-     Non-       Random
        Accession   Family            Species                                 Length      Ribosom V00125 Hexame
        AF252854    Adenoviridae      Bovine adenovirus 2                        33034        19.7     27.6      23.6
        AF030154    Adenoviridae      Bovine adenovirus 3                        34446        13.4     23.0      23.8
        AF036092    Adenoviridae      Bovine adenovirus 4                        31301        22.2     28.1      22.9
        CAV1GENOM   Adenoviridae      Canine adenovirus type 1                   30536        15.3     24.7      23.9
        CAU77082    Adenoviridae      Canine adenovirus type 2                   31323        14.2     23.4      24.3
        AAVEDSDNA   Adenoviridae      Duck adenovirus 1                          33213        21.2     26.8      23.8
        AA46933     Adenoviridae      Fowl adenovirus 1                          43804        28.3     47.1      47.6
        AF083975    Adenoviridae      Fowl adenovirus 9                          45063        16.6     23.8      23.4
        AF224336    Adenoviridae      Frog adenovirus 1                          26163        21.8     26.1      22.8
        AY271307    Adenoviridae      Human adenovirus B                         34794        16.3     25.0      23.9
        AY339865    Adenoviridae      Human adenovirus C                         35934        14.1     23.0      24.3
        ADRGENOME   Adenoviridae      Human adenovirus F                         34214        15.2     25.3      23.5
        AF534906    Adenoviridae      Human adenovirus type 1                    36001        13.7     23.1      24.0
        AY163756    Adenoviridae      Human adenovirus type 11                   34794        16.4     25.1      23.7
        AT12CGA     Adenoviridae      Human adenovirus type 12                   34125        19.4     25.5      23.0
        AF108105    Adenoviridae      Human adenovirus type 17                   35100        11.3     21.3      24.2
        HACG        Adenoviridae      Human adenovirus type 2                    35937        13.4     22.8      23.8
        AY128640    Adenoviridae      Human adenovirus type 35                   34794        16.3     25.0      23.9
        ADRCOMPGE   Adenoviridae      Human adenovirus type 5                    35935        14.1     23.0      24.3
        OA40839     Adenoviridae      Ovine adenovirus 7                         29576        23.3     27.5      23.2
        PAD237815   Adenoviridae      Porcine adenovirus 3                       34094         6.5     19.4      24.2
        AF289262    Adenoviridae      Porcine adenovirus 5                       32621        12.2     24.1      23.8
        AF394196    Adenoviridae      Simian adenovirus 25                       36521        10.0     21.0      24.7
        AF258784    Adenoviridae      Tree shrew adenovirus 1                    33501        14.3     25.3      23.4
        AF074946    Adenoviridae      Turkey adenovirus 3                        26263        24.6     26.4      23.5
        AY358024    Arenaviridae      Guanarito virus                              7081       17.0     27.6      23.8
        AY358022    Arenaviridae      Junin virus                                  7114       17.1     23.8      25.0
        U73034      Arenaviridae      Lassa virus                                  7279       19.2     26.7      25.1
        AF004519    Arenaviridae      Lymphocytic choriomeningitis virus           7219       13.1     23.3      24.5
        AY358021    Arenaviridae      Machupo virus                                7196       16.8     25.6      23.9
        AF427517    Arenaviridae      Pichinde virus                               6997       15.2     25.4      24.6
        AY358026    Arenaviridae      Sabia virus                                  7133       17.2     26.8      24.1
        TACLSEG     Arenaviridae      Tacaribe virus                               7102       19.1     26.4      24.4
        AB033998    Astroviridae      Avian nephritis virus                        6927       17.4     23.7      24.3
        HUANSSPS    Astroviridae      Human astrovirus                             6828       18.8     23.9      24.5
        HA1CAPNS    Astroviridae      Human astrovirus type 1                      6813       16.7     22.8      23.5
        AF260508    Astroviridae      Human astrovirus type 8                      6759       18.0     24.6      25.2
        AY179509    Astroviridae      Mink astrovirus                              6610       14.5     24.9      23.9
        SACAPSID    Astroviridae      Ovine astrovirus                             6440       16.4     22.4      24.3
        AF206663    Astroviridae      Turkey astrovirus                            7355       19.2     25.6      24.7
        BD04608     Bornaviridae      Borna disease virus                          8910       20.0     21.8      23.7
        AF291704    Bunyaviridae      Andes virus                                  6562       30.4     26.8      23.7
        BLCLPA      Bunyaviridae      Bunyamwera virus                             6875       28.7     27.1      24.0
        AF425256    Bunyaviridae      Convict Creek 107 virus                      6562       23.5     26.1      24.4
        AY389508    Bunyaviridae      Crimean-Congo hemorrhagic fever virus      12164        19.3     27.0      24.8
        DVI410617   Bunyaviridae      Dobrava virus                                6532       24.4     26.5      23.5
        DV15018     Bunyaviridae      Dugbe virus                                12255        19.7     25.7      23.8
        HANRDRP4    Bunyaviridae      Hantaan virus                                6533       24.4     25.2      23.6
        AF293665    Bunyaviridae      Hantavirus A9                                6533       22.9     25.9      24.2
        AF288297    Bunyaviridae      Hantavirus L99                               6530       20.7     26.4      23.5
        AF288292    Bunyaviridae      Hantavirus LR1                               6533       24.3     24.6      23.5
        AF189155    Bunyaviridae      Hantavirus Z10                               6533       23.6     27.3      23.8
        AF285266    Bunyaviridae      Hantavirus Z37                               6530       21.4     25.0      23.4
        INSVL       Bunyaviridae      Impatiens necrotic spot virus                8776       22.7     29.7      24.2
        LC12396     Bunyaviridae      La Crosse virus                              6980       30.7     26.5      23.4
        AF484424    Bunyaviridae      Oropouche virus                              6846       26.1     26.3      24.4
        AF025538    Bunyaviridae      Peanut bud necrosis virus                    8911       21.2     29.5      23.1
        PVLSOTKMO   Bunyaviridae      Puumala virus                                6550       22.0     25.6      23.6
        RVFVRMM     Bunyaviridae      Rift Valley fever virus                    11979        17.0     25.0      25.2




                                                                Page 1
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


        SVI410618   Bunyaviridae      Saaremaa virus                               6532   26.9   25.7   23.6
        HVSLSEG     Bunyaviridae      Seoul virus 80-39                            6530   21.6   24.7   23.2
        SNVRPLA     Bunyaviridae      Sin Nombre virus                             6562   23.2   28.8   23.6
        TSWLRPOLM   Bunyaviridae      Tomato spotted wilt virus                    8897   20.0   29.5   23.6
        TVRNAP      Bunyaviridae      Toscana virus                                6404   16.1   21.8   24.0
        TULAJ5637   Bunyaviridae      Tula virus                                   6541   27.1   25.6   24.6
        UUKLRNAP1   Bunyaviridae      Uukuniemi virus                              6423   11.8   23.3   25.3
        AF133128    Bunyaviridae      Watermelon silver mottle virus               8917   22.5   27.2   23.5
        BCA011099   Caliciviridae     Bovine calicivirus                           7338   10.7   21.4   24.7
        AF145896    Caliciviridae     Camberwell virus                             7555   11.2   23.7   24.4
        AB070225    Caliciviridae     Canine calicivirus                           8513   19.3   24.4   24.1
        AB042808    Caliciviridae     Chiba virus                                  7697   17.4   22.3   24.2
        EBHSVORFS   Caliciviridae     European brown hare syndrome virus           7442   13.6   26.5   23.9
        FCLCOMGEN   Caliciviridae     Feline calicivirus                           7690   16.4   25.2   24.4
        HC07611     Caliciviridae     Hawaii calicivirus                           7513   13.4   22.2   24.1
                                      Human calicivirus Hu/NLV/GII/MD145-
        AY032605    Caliciviridae     12/1987/US                                   7556   12.0   23.6   24.0
        HECGENRNA   Caliciviridae     Human calicivirus isolates                   7431   14.8   23.8   24.7
        HCA249939   Caliciviridae     Human calicivirus SLV/Bristol/98/UK          7490   11.9   23.0   23.9
        CRNAORFS    Caliciviridae     Lordsdale virus                              7555   11.6   24.4   23.7
        AY144337    Caliciviridae     Mink enteric calicivirus                     4570    8.9   19.1   24.0
        AY228235    Caliciviridae     Murine norovirus 1                           7382    7.1   21.0   23.9
        NWCRNA      Caliciviridae     Norwalk virus                                7654   17.8   21.3   23.9
        AB039774    Caliciviridae     Norwalk-like virus                           7700   15.5   23.7   24.6
        AF182760    Caliciviridae     Porcine enteric calicivirus                  7320   11.4   23.6   25.4
        AF258618    Caliciviridae     Rabbit hemorrhagic disease virus             7467   13.1   23.0   23.4
        SM15301     Caliciviridae     San Miguel sea lion virus                    8284   13.2   23.5   24.4
        AY134748    Caliciviridae     Snow Mountain virus                          7537   14.3   20.9   24.6
        SOUCAPPRO   Caliciviridae     Southampton virus                            7708   14.3   23.4   23.9
        VEU76874    Caliciviridae     Vesicular exanthema of swine virus           8284   13.0   20.8   24.1
        AF091736    Caliciviridae     VESV-like calicivirus                        8304   13.5   25.2   24.5
        AF321298    Caliciviridae     Walrus calicivirus                           8289   12.3   25.8   24.2
        AY319651    Coronaviridae     Avian infectious bronchitis virus           27733   30.2   27.9   24.0
                                      Avian infectious bronchitis virus (strain
        IBR311317   Coronaviridae     Beaudette CK)                               27635   29.3   27.1   23.5
        AF220295    Coronaviridae     Bovine coronavirus                          31100   31.4   29.9   23.7
        AF304460    Coronaviridae     Human coronavirus 229E                      27317   28.0   28.8   24.1
        AY391777    Coronaviridae     Human coronavirus OC43                      30738   30.0   29.9   23.7
        AF029248    Coronaviridae     Murine hepatitis virus                      31357   26.7   27.5   23.5
        AF201929    Coronaviridae     Murine hepatitis virus strain 2             31276   27.2   28.5   23.7
        AF207902    Coronaviridae     Murine hepatitis virus strain ML-11         31277   27.4   28.6   23.7
        AF353511    Coronaviridae     Porcine epidemic diarrhea virus             28033   26.4   27.2   24.3
        AY427439    Coronaviridae     SARS coronavirus AS                         29711   24.2   25.3   23.6
        AY278488    Coronaviridae     SARS coronavirus BJ01                       29725   24.3   25.3   23.6
        AY278487    Coronaviridae     SARS coronavirus BJ02                       29745   24.3   25.4   23.6
        AY278490    Coronaviridae     SARS coronavirus BJ03                       29740   24.3   25.3   23.6
        AY279354    Coronaviridae     SARS coronavirus BJ04                       29732   24.2   25.3   23.6
        AY282752    Coronaviridae     SARS coronavirus CUHK-Su10                  29736   24.2   25.2   23.6
        AY278554    Coronaviridae     SARS coronavirus CUHK-W1                    29736   24.1   25.2   23.6
        AY310120    Coronaviridae     SARS coronavirus FRA                        29740   24.3   25.2   23.6
        AY291315    Coronaviridae     SARS coronavirus Frankfurt 1                29727   24.4   25.2   23.6
        AY278489    Coronaviridae     SARS coronavirus GD01                       29757   24.0   25.3   23.6
        AY304495    Coronaviridae     SARS coronavirus GZ50                       29720   24.2   25.3   23.6
        AY278491    Coronaviridae     SARS coronavirus HKU-39849                  29742   24.2   25.3   23.6
        AY323977    Coronaviridae     SARS coronavirus HSR 1                      29751   24.2   25.2   23.6
        AY350750    Coronaviridae     SARS coronavirus PUMC01                     29738   24.1   25.2   23.6
        AY357075    Coronaviridae     SARS coronavirus PUMC02                     29738   24.1   25.2   23.6
        AY357076    Coronaviridae     SARS coronavirus PUMC03                     29745   24.1   25.2   23.6
        AY283794    Coronaviridae     SARS coronavirus Sin2500                    29711   24.3   25.2   23.6
        AY283795    Coronaviridae     SARS coronavirus Sin2677                    29705   24.3   25.3   23.6
        AY283796    Coronaviridae     SARS coronavirus Sin2679                    29711   24.2   25.2   23.6
        AY283797    Coronaviridae     SARS coronavirus Sin2748                    29706   24.3   25.3   23.6




                                                                   Page 2
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


        AY283798    Coronaviridae     SARS coronavirus Sin2774                     29711   24.3   25.3   23.6
        AY461660    Coronaviridae     SARS coronavirus SoD                         29715   24.4   25.2   23.6
        AY304488    Coronaviridae     SARS coronavirus SZ16                        29731   23.9   25.4   23.6
        AY304486    Coronaviridae     SARS coronavirus SZ3                         29741   23.9   25.3   23.6
        AY338174    Coronaviridae     SARS coronavirus Taiwan TC1                  29573   24.2   25.3   23.6
        AY338175    Coronaviridae     SARS coronavirus Taiwan TC2                  29573   24.2   25.3   23.6
        AY348314    Coronaviridae     SARS coronavirus Taiwan TC3                  29573   24.2   25.3   23.7
        AY274119    Coronaviridae     SARS coronavirus Tor2                        29751   24.2   25.2   23.6
        AY291451    Coronaviridae     SARS coronavirus TW1                         29729   24.2   25.3   23.6
        AY321118    Coronaviridae     SARS coronavirus TWC                         29725   24.2   25.2   23.6
        AY362698    Coronaviridae     SARS coronavirus TWC2                        29727   24.2   25.2   23.6
        AY362699    Coronaviridae     SARS coronavirus TWC3                        29727   24.2   25.2   23.6
        AP006557    Coronaviridae     SARS coronavirus TWH                         29727   24.2   25.2   23.6
        AP006558    Coronaviridae     SARS coronavirus TWJ                         29725   24.2   25.2   23.6
        AP006559    Coronaviridae     SARS coronavirus TWK                         29727   24.2   25.3   23.6
        AP006560    Coronaviridae     SARS coronavirus TWS                         29727   24.2   25.2   23.6
        AP006561    Coronaviridae     SARS coronavirus TWY                         29727   24.2   25.2   23.6
        AY278741    Coronaviridae     SARS coronavirus Urbani                      29727   24.2   25.2   23.6
        AY394850    Coronaviridae     SARS coronavirus WHU                         29735   24.3   25.2   23.6
        AY297028    Coronaviridae     SARS coronavirus ZJ01                        29715   24.1   25.2   23.6
        AY351680    Coronaviridae     SARS coronavirus ZMY 1                       29749   23.9   25.2   23.6
        TGA271965   Coronaviridae     Transmissible gastroenteritis virus          28586   27.4   29.3   24.1
        AY358025    Filoviridae       Marburg virus                                19151   21.9   24.9   24.5
        AF522874    Filoviridae       Reston Ebola virus                           18891   22.6   24.4   25.0
        AY354458    Filoviridae       Zaire Ebola virus                            18961   20.8   26.2   25.1
        AF331718    Flaviviridae      Alkhurma virus                               10685    9.7   21.1   24.3
        AF160193    Flaviviridae      Apoi virus                                   10116   13.6   23.6   24.3
        BDU70263    Flaviviridae      Border disease virus strain BD31             12268   22.0   23.9   23.1
        BDAF2227    Flaviviridae      Border disease virus strain C413             12255   23.1   22.8   23.4
        AF037405    Flaviviridae      Border disease virus strain X818             12333   23.1   24.2   23.4
                                      Bovine viral diarrhea virus genotype 2
        AF145967    Flaviviridae      (BVDV-2)                                     12333   21.9   22.6   23.4
                                      Bovine viral diarrhea virus strain Oregon
        AF091605    Flaviviridae      C24V                                         12310   23.4   22.0   23.3
        BVDPP       Flaviviridae      Bovine viral diarrhea virus strain Osloss    12480   21.6   23.3   23.7
        AJ585412    Flaviviridae      Bovine viral diarrhea virus VEDEVAC          12308   21.2   23.4   24.0
        AB078952    Flaviviridae      Bovine viral diarrhea virus-1                13203   21.6   22.3   23.9
        AF352565    Flaviviridae      Classical swine fever virus                  12344   20.4   22.9   23.4
        AF407339    Flaviviridae      Classical swine fever virus 39               12297   20.5   21.8   23.1
        AF326963    Flaviviridae      Classical swine fever virus strain Eystrup   12301   21.1   22.4   23.2
        AF311056    Flaviviridae      Deer tick virus                              10800   11.3   21.9   24.1
        DVU88537    Flaviviridae      Dengue virus type 1                          10735   13.5   24.9   23.6
        AF038403    Flaviviridae      Dengue virus type 2                          10724   14.0   21.5   23.2
        DVU411      Flaviviridae      Dengue virus type 2 (strain 16681)           10723   14.5   21.5   23.4
        AY099337    Flaviviridae      Dengue virus type 3                          10707   15.3   23.8   24.1
        AF289029    Flaviviridae      Dengue virus type 4                          10665   14.3   22.0   23.9
        FLVCFAPP    Flaviviridae      Flavivirus sp.                               10695   12.1   23.5   24.1
        AF070476    Flaviviridae      GB virus C variant troglodytes                9250   13.4   22.6   24.0
                                      GB virus C/Hepatitis G virus (Hepatitis GB
        AF104403    Flaviviridae      virus C / Hepatitis G virus)                  9056   11.5   21.6   24.1
        AF177036    Flaviviridae      Hepatitis C virus                             9711   13.2   21.2   23.0
        AF011753    Flaviviridae      Hepatitis C virus strain H77                  9599   11.6   21.5   24.5
        HCJ238799   Flaviviridae      Hepatitis C virus type 1b                     9605   12.6   20.5   25.0
        AB030907    Flaviviridae      Hepatitis C virus type 2b                     9654   12.8   21.0   24.2
        HPCHCVTR1   Flaviviridae      Hepatitis C virus type 3b                     9444   15.0   21.1   23.5
        HCV4APOLY   Flaviviridae      Hepatitis C virus type 4a                     9355   15.0   22.3   24.1
        HCV1480     Flaviviridae      Hepatitis C virus type 5a                     9343   14.2   20.2   23.9
        HCV12083    Flaviviridae      Hepatitis C virus type 6a                     9340   14.5   21.8   24.1
        AF121950    Flaviviridae      Hepatitis G virus                             9395   10.0   22.6   24.3
        AF309966    Flaviviridae      Hepatitis G virus isolate PEI                 9292    9.1   19.0   21.6
        HGD90600    Flaviviridae      Hepatitis GB virus C                          9395   11.3   22.7   24.0
        AY184212    Flaviviridae      Japanese encephalitis virus                  10978   12.6   22.5   24.6
        AY149905    Flaviviridae      Kamiti River virus                           11375   14.6   23.2   24.0




                                                                 Page 3
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


        AY274505    Flaviviridae      Kunjin virus                                  11022   13.7   22.8   24.6
        AF253420    Flaviviridae      Langat virus                                  10943    9.7   19.3   23.6
        LIVGEN      Flaviviridae      Louping ill virus                             10871    8.8   21.9   24.2
        MVI242984   Flaviviridae      Modoc virus                                   10600   15.7   24.6   24.2
        MMY299445   Flaviviridae      Montana myotis leukoencephalitis virus        10690   13.3   25.9   24.4
        AF161266    Flaviviridae      Murray Valley encephalitis virus              11014   13.6   23.2   24.8
        AY193805    Flaviviridae      Omsk hemorrhagic fever virus                  10787    8.6   21.2   24.5
        AF144617    Flaviviridae      Pestivirus giraffe-1 H138                     12602   20.7   21.3   23.8
        AF144618    Flaviviridae      Pestivirus reindeer-1 V60-Krefeld             12318   20.1   24.2   22.7
        PTU86599    Flaviviridae      Pestivirus type 1                             15521   20.4   23.0   23.6
        PTU90951    Flaviviridae      Pestivirus type 2                             12298   21.4   22.4   23.3
        PWARPT1     Flaviviridae      Powassan virus                                10839   11.0   21.1   24.8
        AF144692    Flaviviridae      Rio Bravo virus                               10140   14.6   24.8   24.4
        AF285080    Flaviviridae      Tamana bat virus                              10053   18.8   25.2   23.8
        TE27495     Flaviviridae      Tick-borne encephalitis virus                 11141    9.0   21.5   24.1
        AF533540    Flaviviridae      West Nile virus                               11029   10.7   22.1   25.2
        YFVRNA      Flaviviridae      Yellow fever virus                            10862    9.4   21.9   24.8
        AB114858    Flaviviridae      Yokose virus                                  10857   14.1   23.6   24.7
        AG29144     Hepadnaviridae    Arctic ground squirrel hepatitis B virus       3302   13.0   21.8   24.5
        CHE441111   Hepadnaviridae    Crane hepatitis B virus                        3021   20.7   25.3   24.1
        S65868      Hepadnaviridae    Duck hepatitis B virus                         3218   16.9   19.7   22.5
        NCGSVHXX    Hepadnaviridae    Ground squirrel hepatitis virus                3311   16.3   23.7   24.4
        HBVDEFVP2   Hepadnaviridae    Hepatitis B virus                              3297   15.8   18.0   23.2
        HPBADW3     Hepadnaviridae    Hepatitis B virus subtype ADW                  3215   15.1   18.4   22.9
        HSHBV       Hepadnaviridae    Hepatitis B virusHomo sapiens (human)          3995   10.3   18.4   21.3
        HBHCG       Hepadnaviridae    Heron hepatitis B virus                        3027   18.5   19.5   24.4
                                      Marmota monax (woodchuck)Woodchuck
        MMRNAB3NL   Hepadnaviridae    hepatitis B virus                              2485   18.3   25.2   24.1
        AF193864    Hepadnaviridae    Orangutan hepadnavirus                         3182   12.2   18.5   24.2
        AF111000    Hepadnaviridae    Snow goose hepatitis B virus                   3024   27.2   21.4   24.3
        SHE251937   Hepadnaviridae    Stork hepatitis B virus                        3033   19.2   21.8   23.9
        WHVB3N      Hepadnaviridae    Woodchuck hepatitis B virus                    4305   20.2   24.7   22.0
        AY226578    Hepadnaviridae    Woolly monkey hepatitis B Virus                3179    9.7   22.5   22.9
                                      Alcelaphine herpesvirus 1 (wildebeest
        AF005370    Herpesviridae     herpesvirus)                                 130608   17.3   24.7   23.6
        AY261359    Herpesviridae     Bovine herpesvirus 5                         138390    4.3   17.6   23.5
                                      Bovine herpesvirus type 1.1Bovine
                                      herpesvirus type 1.1 (strain Cooper)Bovine
                                      herpesvirus type 1.2 (strain K22)Bovine
                                      herpesvirus type 1.1 (strain P8-2)Bovine
                                      herpesvirus type 1.1 (strain 34)Bovine
        BHV1CGEN    Herpesviridae     herpesvirus type 1.1 (strain Jura)           135301    5.5   19.5   23.5
        AF319782    Herpesviridae     Callitrichine herpesvirus 3                  149696   16.7   22.7   23.3
                                      Cercopithecine herpesvirus 1 (monkey B
        AF533768    Herpesviridae     virus)                                       156789    3.7   16.4   23.1
        AF275348    Herpesviridae     Cercopithecine herpesvirus 7                 124138   29.2   26.9   22.8
        AY037858    Herpesviridae     Cercopithicine herpesvirus 15                171096    8.2   18.4   24.4
        AF480884    Herpesviridae     Chimpanzee cytomegalovirus                   241087   10.7   21.0   24.1
        EHU20824    Herpesviridae     Equid herpesvirus 2                          184427    9.9   19.6   23.7
        HEHSECOMG   Herpesviridae     Equine herpesvirus 1                         150223   16.1   22.5   23.9
        AF030027    Herpesviridae     Equine herpesvirus 4                         145597   20.5   24.8   23.7
        AF243438    Herpesviridae     Gallid herpesvirus 2                         177874   25.5   24.7   22.9
        AB049735    Herpesviridae     Gallid herpesvirus 3                         164270   19.2   23.3   23.0
        HE1CG       Herpesviridae     Human herpesvirus 1                          152261    7.1   18.3   23.8
        HSV2HG52    Herpesviridae     Human herpesvirus 2                          154746    6.1   17.6   23.8
        AB097933    Herpesviridae     Human herpesvirus 3                          125125   23.7   24.8   22.8
        HEHS4B958   Herpesviridae     Human herpesvirus 4 (Epstein-Barr virus)     184113    9.8   17.9   24.5
        AC146906    Herpesviridae     Human herpesvirus 5                          234881   13.4   22.9   24.1
        AB021506    Herpesviridae     Human herpesvirus 6                          161573   21.0   26.0   22.8
        AF157706    Herpesviridae     Human herpesvirus 6B                         162114   20.8   26.0   22.8
        AF037218    Herpesviridae     Human herpesvirus 7                          153080   20.8   27.2   22.8
                                      Human herpesvirus 8 (Kaposis sarcoma-
                                      associated herpesvirus - Humanherpesvirus
        KSU75698    Herpesviridae     8)                                           137508   15.0   22.6   23.4




                                                                  Page 4
Endoh et al. Supplement for Table 5                           ProbUniqueVirus


        HECHCCOMG   Herpesviridae       Ictalurid herpesvirus 1                    134226   13.0   19.7   23.7
        AF083501    Herpesviridae       Macaca mulatta rhadinovirus 17577          133719   17.3   23.7   23.5
        AF210726    Herpesviridae       Macaca mulatta rhadinovirus 26-95          130733   17.4   23.9   23.4
                                        Meleagrid herpesvirus 1 (herpesvirus of
        AF291866    Herpesviridae       turkeys)                                   159160   23.4   24.6   23.3
        MCU68299    Herpesviridae       Mouse cytomegalovirus 1                    230278   12.1   21.1   23.9
        AY372243    Herpesviridae       Psittacid herpesvirus 1                    163025   13.1   21.3   23.4
        AF232689    Herpesviridae       Rat cytomegalovirus Maastricht             230138   10.2   20.4   23.4
        AY186194    Herpesviridae       Rhesus cytomegalovirus strain 68-1         221454   18.5   24.4   23.7
        AF281817    Herpesviridae       Tupaia herpesvirus                         195859    7.9   19.8   24.1
        AY150217    Iridoviridae        Ambystoma tigrinum stebbensi virus         106332   14.1   20.8   23.6
        AF303741    Iridoviridae        Chilo iridescent virus                     212482   25.2   29.3   21.9
        AF371960    Iridoviridae     Infectious spleen and kidney necrosis virus   111362   17.7   23.3   23.5
        IVAFPVR     Orthomyxoviridae Avian influenza virus                           2233   14.8   27.8   25.4
        DHVPB1      Orthomyxoviridae Dhori virus                                     2224   15.3   24.7   25.3
        EIVH3A      Orthomyxoviridae Equine influenza virus                          1762   18.7   22.1   25.2
        S64310      Orthomyxoviridae Equine influenza virus H3N8                     1754   18.0   22.2   25.1
        ORINF8      Orthomyxoviridae Fowl plague virus                               1742   15.5   25.0   22.1
        S67220      Orthomyxoviridae H1N1 swine influenza virus                      1770   20.6   22.6   23.8
                                        Homo sapiens (human)Influenza B virus
        ORFLBL40    Orthomyxoviridae (B/Lee/40)                                      2381   16.6   23.9   23.1
        AY168787    Orthomyxoviridae Infectious salmon anemia virus                  2260   15.7   24.6   21.8
        ORWS33P3    Orthomyxoviridae Influenza A virus                               2341   16.3   24.3   24.5
        INA489851   Orthomyxoviridae Influenza A virus (A/1496/02(H1N2))             1407   26.3   21.7   25.1
        INFA81HO    Orthomyxoviridae Influenza A virus (A/81/HO)                     1565   11.2   23.0   23.9
                                        Influenza A virus (A/Afri.Star./Eng-
        AF202232    Orthomyxoviridae Q/938/79(H7N1))                                 1732   13.9   23.4   23.6
                                        Influenza A virus (A/Alma
        S62154      Orthomyxoviridae    Ata/1417/84(H1N1))                           1778   21.4   18.6   24.4
                                        Influenza A virus (A/aquatic bird/Hong
        INA427297   Orthomyxoviridae    Kong/399/99(H3N8))                           1701   12.6   25.9   24.6
                                        Influenza A virus (A/Aquatic bird/Hong
        AF250472    Orthomyxoviridae    Kong/M603/98(H11N1))                         1497    8.0   18.0   24.3
                                        Influenza A virus
        INA457961   Orthomyxoviridae    (A/Asuncion/918/2001(H3N2))                  1391   21.9   22.6   23.9
        AF316814    Orthomyxoviridae    Influenza A virus (A/Athens/1/98 (H3N2))     1372   22.2   21.5   25.1
                                        Influenza A virus (A/Athens/135/99
        AF316810    Orthomyxoviridae    (H3N2))                                      1402   26.7   22.5   24.6
        AF316815    Orthomyxoviridae Influenza A virus (A/Athens/16/98 (H3N2))       1382   22.4   23.5   25.5
        AF316812    Orthomyxoviridae Influenza A virus (A/Athens/2/97 (H3N2))        1379   22.5   21.4   24.8
        AF316805    Orthomyxoviridae Influenza A virus (A/Athens/76/98 (H3N2))       1402   22.5   23.2   24.9
        AF316813    Orthomyxoviridae Influenza A virus (A/Athens/8/97 (H3N2))        1255   24.3   24.7   25.0
        AF316806    Orthomyxoviridae Influenza A virus (A/Athens/94/98 (H3N2))       1339   21.7   21.7   24.9
                                        Influenza A virus (A/avian/NY/118353-
        AY240877    Orthomyxoviridae    1/01(H7N2))                                  1670   15.0   28.1   22.9
                                        Influenza A virus (A/avian/NY/31588-
        AY300931    Orthomyxoviridae    2/00(H5N2))                                  1410   18.1   25.9   26.7
                                        Influenza A virus (A/avian/NY/31588-
        AY296070    Orthomyxoviridae    3/00(H5N2))                                  1732   20.8   28.3   24.6
                                        Influenza A virus
        AY300936    Orthomyxoviridae    (A/avian/NY/53726/00(H5N2))                  1410   18.1   25.9   26.7
                                        Influenza A virus (A/avian/NY/70411-
        AY240878    Orthomyxoviridae    12/00(H7N2))                                 1670   16.5   28.7   23.2
                                        Influenza A virus (A/avian/NY/73063-
        AY240925    Orthomyxoviridae    6/00(H7N2))                                  1670   15.0   26.6   22.8
                                        Influenza A virus (A/avian/NY/74211-
        AY240879    Orthomyxoviridae    2/00(H7N2))                                  1676   15.5   27.7   23.2
                                        Influenza A virus (A/avian/NY/76247-
        AY240880    Orthomyxoviridae    3/00(H7N2))                                  1676   15.5   28.6   22.6
                                        Influenza A virus (A/avian/NY/7729-
        AY240882    Orthomyxoviridae    6/00(H7N2))                                  1676   15.8   28.0   23.2
                                        Influenza A virus (A/avian/NY/81746-
        AY240881    Orthomyxoviridae    5/00(H7N2))                                  1676   14.9   25.7   23.4




                                                                    Page 5
Endoh et al. Supplement for Table 5                          ProbUniqueVirus


                                        Influenza A virus (A/Bantam/Nanchang/9-
        AY180837    Orthomyxoviridae 366/2000(H3N3))                               1410   21.6   22.0   25.6
        IVI518104   Orthomyxoviridae Influenza A virus (A/Bayern/7/95(H1N1))       1459   15.1   28.8   24.4
        AY289928    Orthomyxoviridae Influenza A virus (A/Beijing/262/95(H1N1))    1775   19.4   22.5   24.2
        IAU740      Orthomyxoviridae Influenza A virus (A/Beijing/353/89(H3N2))    1714   13.4   25.7   23.9
        FLABER68H   Orthomyxoviridae Influenza A virus (A/Berkeley/1/68(H2N2))     1773   16.9   29.3   25.2
        FLABLN64H   Orthomyxoviridae Influenza A virus (A/Berlin/3/64 (H2N2))      1773   14.4   26.5   25.3
        IVI252129   Orthomyxoviridae Influenza A virus (A/Berlin/6/88(H3N2))       1759   14.5   26.4   23.5
                                        Influenza A virus (A/blue-winged
        AY300951    Orthomyxoviridae teal/TX/2/01(H7N3))                           1410   18.4   24.5   23.5
                                        Influenza A virus
        IVI518093   Orthomyxoviridae    (A/Bratislava/47/2000(H1N1))               1451   18.6   28.3   24.1
                                        Influenza A virus
        INA458277   Orthomyxoviridae    (A/Bratislava/6/97(H3N2))                  1565   12.1   22.7   25.2
        ORFLAB78    Orthomyxoviridae    Influenza A virus (A/Brazil/11/78(H1N1))   1565   12.8   22.0   23.8
                                        Influenza A virus
        AF250356    Orthomyxoviridae    (A/Brevig_Mission/1/1918(H1N1))            1410   20.2   25.9   25.5
                                        Influenza A virus (A/Buenos
        AF533738    Orthomyxoviridae    Aires/T28/98(H3N2))                        1466   22.9   22.2   24.9
                                        Influenza A virus (A/Buenos
        AF533739    Orthomyxoviridae    Aires/V191/98(H3N2))                       1466   22.9   22.2   24.8
                                        Influenza A virus (A/Buenos
        AF533737    Orthomyxoviridae    Aires/V235/98(H3N2))                       1466   22.2   22.2   24.8
                                        Influenza A virus
        ORFLACA7    Orthomyxoviridae    (A/California/10/78(H1N1))                 1565   13.4   23.0   25.0
                                        Influenza A virus
        AF398864    Orthomyxoviridae    (A/Charlottesville/28/95(H1N1))            2219   13.3   24.8   24.7
                                        Influenza A virus
        AF398866    Orthomyxoviridae    (A/Charlottesville/31/95(H1N1))            2287   17.7   22.3   23.5
                                        Influenza A virus
        AF461511    Orthomyxoviridae    (A/Chicken/Anhui/1/98(H9N2))               1683   21.4   22.6   23.8
                                        Influenza A virus
        AF156438    Orthomyxoviridae    (A/Chicken/Beijing/1/94(H9N2))             2263   16.6   21.9   23.6
                                        Influenza A virus
        AF536689    Orthomyxoviridae    (A/Chicken/Beijing/1/95(H9N2))             1478   20.3   20.6   23.8
                                        Influenza A virus
        AF461530    Orthomyxoviridae    (A/Chicken/Beijing/1/97(H9N2))             1683   27.0   21.4   23.3
                                        Influenza A virus
        AF536690    Orthomyxoviridae    (A/Chicken/Beijing/2/97(H9N2))             1478   21.0   18.9   22.7
                                        Influenza A virus
        AF536691    Orthomyxoviridae    (A/Chicken/Beijing/3/99(H9N2))             1478   19.3   22.3   24.0
                                        Influenza A virus
        AF474070    Orthomyxoviridae    (A/Chicken/California/0139/2001(H6N2))     1540   12.3   21.1   23.8
                                        Influenza A virus
        AF474042    Orthomyxoviridae    (A/Chicken/California/1002/2000(H6N2))     1380   20.3   27.2   24.9
                                        Influenza A virus
        AF457671    Orthomyxoviridae    (A/chicken/California/1002a/00(H6N2))      2356   15.9   23.1   23.9
                                        Influenza A virus
        AF474044    Orthomyxoviridae    (A/Chicken/California/1316/2001(H6N2))     1380   21.7   25.4   25.9
                                        Influenza A virus
        AF457706    Orthomyxoviridae    (A/chicken/California/139/01(H6N2))        2309   16.7   23.8   23.4
                                        Influenza A virus
        AF457697    Orthomyxoviridae    (A/chicken/California/431/00(H6N2))        2304   13.0   25.0   25.3
                                        Influenza A virus
        AF474029    Orthomyxoviridae    (A/Chicken/California/431/2000(H6N2))      1713   21.3   26.6   22.9
                                        Influenza A virus
        AF457690    Orthomyxoviridae    (A/chicken/California/465/00(H6N2))        2309   16.2   23.4   24.3
                                        Influenza A virus
        AF474040    Orthomyxoviridae    (A/Chicken/California/465/2000(H6N2))      1380   20.3   26.8   25.4
                                        Influenza A virus
        AF474069    Orthomyxoviridae    (A/Chicken/California/650/2000(H6N2))      1540   11.7   21.1   24.6
                                        Influenza A virus
        AF457682    Orthomyxoviridae    (A/chicken/California/6643/01(H6N2))       2307   14.7   25.0   23.9
                                        Influenza A virus
        AF474035    Orthomyxoviridae    (A/Chicken/California/6643/2001(H6N2))     1713   20.4   28.0   23.5
                                        Influenza A virus
        AF474046    Orthomyxoviridae    (A/Chicken/California/8892/2001(H6N2))     1380   21.7   25.4   25.7




                                                                   Page 6
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus
        AF457673    Orthomyxoviridae (A/chicken/California/905/01(H6N2))        2308   14.8   24.2   24.7
                                       Influenza A virus
        AF474047    Orthomyxoviridae   (A/Chicken/California/9174/2001(H6N2))   1380   21.7   25.4   25.7
                                       Influenza A virus
        AF474048    Orthomyxoviridae   (A/Chicken/California/9420/2001(H6N2))   1380   21.0   26.1   25.4
                                       Influenza A virus
        AF202236    Orthomyxoviridae   (A/chicken/England/71/82(H7N1))          1671    9.9   25.4   22.9
                                       Influenza A virus (A/chicken/FL/90348-
        AY240883    Orthomyxoviridae   4/01(H7N2))                              1676   16.4   28.6   23.5
                                       Influenza A virus
        AF461513    Orthomyxoviridae   (A/Chicken/Gangxi/1/00(H9N2))            1683   24.1   21.7   22.7
                                       Influenza A virus
        AF461514    Orthomyxoviridae   (A/Chicken/Gangxi/2/00(H9N2))            1683   22.3   22.9   23.2
                                       Influenza A virus
        AF461512    Orthomyxoviridae   (A/Chicken/Gansu/1/99(H9N2))             1683   20.5   22.0   23.5
                                       Influenza A virus
        AF536692    Orthomyxoviridae   (A/Chicken/Guangdong/97(H9N2))           1478   18.9   20.3   24.0
                                       Influenza A virus
        AF384557    Orthomyxoviridae   (A/Chicken/Guangdong/SS/94(H9N2))        1683   23.2   22.6   23.8
                                       Influenza A virus
        AF461515    Orthomyxoviridae   (A/chicken/Hebei/1/00(H9N2))             1683   21.4   22.6   23.9
                                       Influenza A virus
        AF536693    Orthomyxoviridae   (A/Chicken/Hebei/1/96(H9N2))             1478   21.0   21.7   23.4
                                       Influenza A virus
        AF461531    Orthomyxoviridae   (A/Chicken/Hebei/2/00(H9N2))             1683   22.9   22.0   22.7
                                       Influenza A virus
        AF536694    Orthomyxoviridae   (A/Chicken/Hebei/2/98(H9N2))             1478   20.3   19.6   22.3
                                       Influenza A virus
        AF536695    Orthomyxoviridae   (A/Chicken/Hebei/3/98(H9N2))             1478   21.0   19.3   22.9
                                       Influenza A virus
        AF461516    Orthomyxoviridae   (A/Chicken/Henan/1/99(H9N2))             1683   24.7   20.5   22.8
                                       Influenza A virus
        AF461517    Orthomyxoviridae   (A/Chicken/Henan/2/98(H9N2))             1683   21.4   22.9   24.3
                                       Influenza A virus
        AF536696    Orthomyxoviridae   (A/Chicken/Henan/98(H9N2))               1478   20.6   18.6   22.8
                                       Influenza A virus
                                       (A/Chicken/Hidalgo/26654-1368/94
        AF098585    Orthomyxoviridae   (H5N2))                                  2273   13.9   27.5   25.4
                                       Influenza A virus (A/chicken/Hong
        INA410547   Orthomyxoviridae   Kong/17/77(H6N1))                        1701   27.6   22.6   23.1
                                       Influenza A virus (A/Chicken/Hong
        AF098547    Orthomyxoviridae   Kong/220/97 (H5N1))                      1318   15.2   23.1   25.7
                                       Influenza A virus (A/Chicken/Hong
        AF098577    Orthomyxoviridae   Kong/258/97 (H5N1))                      2273   20.5   24.6   24.1
                                       Influenza A virus (A/Chicken/Hong
        AY075027    Orthomyxoviridae   Kong/317.5/2001(H5N1))                   1748   17.2   22.9   23.7
                                       Influenza A virus (A/Chicken/Hong
        AF509025    Orthomyxoviridae   Kong/715.5/01 (H5N1))                    1668   17.4   21.0   23.7
                                       Influenza A virus (A/Chicken/Hong
        AF098579    Orthomyxoviridae   Kong/728/97 (H5N1))                      2273   20.5   24.9   24.1
                                       Influenza A virus (A/Chicken/Hong
        AF156436    Orthomyxoviridae   Kong/739/94(H9N2))                       2261   18.8   22.1   24.4
                                       Influenza A virus (A/Chicken/Hong
        AF509179    Orthomyxoviridae   Kong/751.1/01 (H5N1))                    1485   13.1   24.9   25.0
                                       Influenza A virus (A/Chicken/Hong
        AF098580    Orthomyxoviridae   Kong/786/97 (H5N1))                      2273   20.5   24.9   24.0
                                       Influenza A virus (A/Chicken/Hong
        AF509180    Orthomyxoviridae   Kong/822.1/01 (H5N1))                    1485   14.8   24.6   22.9
                                       Influenza A virus (A/Chicken/Hong
        AF509181    Orthomyxoviridae   Kong/829.2/01 (H5N1))                    1485   13.1   24.9   24.8
                                       Influenza A virus (A/Chicken/Hong
        AF509028    Orthomyxoviridae   Kong/830.2/01 (H5N1))                    1529   17.0   20.6   22.9
                                       Influenza A virus (A/Chicken/Hong
        AF509029    Orthomyxoviridae   Kong/858.3/01 (H5N1))                    1554   16.7   20.9   22.9
                                       Influenza A virus (A/Chicken/Hong
        AF509184    Orthomyxoviridae   Kong/866.3/01 (H5N1))                    1485   13.1   23.9   22.8
                                       Influenza A virus (A/Chicken/Hong
        AF509185    Orthomyxoviridae   Kong/867.1/01 (H5N1))                    1485   13.8   24.6   22.9
                                       Influenza A virus (A/Chicken/Hong
        AF509032    Orthomyxoviridae   Kong/873.3/01 (H5N1))                    1537   16.6   20.8   23.2




                                                                Page 7
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus (A/Chicken/Hong
        AF509033    Orthomyxoviridae Kong/876.1/01 (H5N1))                   1537   16.9   20.5   22.7
                                       Influenza A virus (A/Chicken/Hong
        AF509031    Orthomyxoviridae   Kong/879.1/01 (H5N1))                 1668   17.7   20.7   23.4
                                       Influenza A virus (A/Chicken/Hong
        AF509034    Orthomyxoviridae   Kong/891.1/01 (H5N1))                 1659   18.4   20.5   23.0
                                       Influenza A virus (A/Chicken/Hong
        AF509035    Orthomyxoviridae   Kong/893.2/01 (H5N1))                 1497   17.4   20.7   22.7
                                       Influenza A virus (A/Chicken/Hong
        AF098581    Orthomyxoviridae   Kong/915/97 (H5N1))                   2273   19.8   23.8   24.5
                                       Influenza A virus (A/Chicken/Hong
        AF509019    Orthomyxoviridae   Kong/FY150/01 (H5N1))                 1644   17.6   20.7   23.4
                                       Influenza A virus (A/Chicken/Hong
        AF222647    Orthomyxoviridae   Kong/FY20/99(H9N2))                   1659   11.8   26.2   26.1
                                       Influenza A virus (A/Chicken/Hong
        AF509016    Orthomyxoviridae   Kong/FY77/01 (H5N1))                  1650   16.7   20.6   23.5
                                       Influenza A virus (A/Chicken/Hong
        AF156431    Orthomyxoviridae   Kong/G23/97(H9N2))                    2276   20.4   25.7   23.8
                                       Influenza A virus (A/Chicken/Hong
        AF156417    Orthomyxoviridae   Kong/G23/99 (H9N2))                   2242   10.7   26.3   24.6
                                       Influenza A virus (A/Chicken/Hong
        AF156430    Orthomyxoviridae   Kong/G9/97(H9N2))                     2281   21.0   25.9   24.0
                                       Influenza A virus (A/Chicken/Hong
        AF222648    Orthomyxoviridae   Kong/KC12/99(H9N2))                   1659   12.1   27.7   25.2
                                       Influenza A virus (A/Chicken/Hong
        AF222644    Orthomyxoviridae   Kong/NT16/99(H9N2))                   1659   17.2   24.7   24.3
                                       Influenza A virus (A/Chicken/Hong
        AF222650    Orthomyxoviridae   Kong/SF2/99(H9N2))                    1659   12.1   27.1   25.4
                                       Influenza A virus (A/Chicken/Hong
        AF509024    Orthomyxoviridae   Kong/SF219/01 (H5N1))                 1654   17.5   20.9   23.0
                                       Influenza A virus (A/chicken/Hong
        AY206677    Orthomyxoviridae   Kong/WF2/99(H9N2))                    1683   25.8   22.3   23.4
                                       Influenza A virus (A/Chicken/Hong
        AF098541    Orthomyxoviridae   Kong/y385/97 (H5N1))                  1726   18.0   21.1   23.7
                                       Influenza A virus (A/Chicken/Hong
        AF098591    Orthomyxoviridae   Kong/y388/97 (H5N1))                  2228   10.5   25.4   24.6
                                       Influenza A virus (A/Chicken/Hong
        AF509170    Orthomyxoviridae   Kong/YU562/01 (H5N1))                 1944   16.5   24.7   22.7
                                       Influenza A virus (A/Chicken/Hong
        AF509197    Orthomyxoviridae   Kong/YU563/01 (H5N1))                 2223   13.9   26.5   25.1
                                       Influenza A virus
        AY221587    Orthomyxoviridae   (A/Chicken/HongKong/FY150/01(H5N1))   2279   15.8   22.4   24.7
                                       Influenza A virus
                                       (A/Chicken/HongKong/FY150/01-
        AY221586    Orthomyxoviridae   MB(H5N1))                             2279   15.8   22.8   24.7
                                       Influenza A virus
        AY221585    Orthomyxoviridae (A/Chicken/HongKong/NT873.3/01(H5N1))   2279   14.7   22.8   24.9
                                       Influenza A virus
                                       (A/Chicken/HongKong/NT873.3/01-
        AY221584    Orthomyxoviridae   MB(H5N1))                             2279   14.3   23.3   25.0
                                       Influenza A virus
        AY221592    Orthomyxoviridae   (A/Chicken/HongKong/YU562/01(H5N1))   2279   14.9   23.0   23.9
                                       Influenza A virus
        AY221591    Orthomyxoviridae (A/Chicken/HongKong/YU822.2/01(H5N1))   2279   14.7   22.6   24.2
                                       Influenza A virus
                                       (A/Chicken/HongKong/YU822.2/01-
        AY221590    Orthomyxoviridae   MB(H5N1))                             2279   14.9   22.8   24.4
                                       Influenza A virus
        AF202239    Orthomyxoviridae   (A/chicken/Ireland/1733/89(H7N7))     1633   11.3   23.9   22.5
                                       Influenza A virus
        AF202255    Orthomyxoviridae   (A/chicken/Italy/1081/99(H7N1))       1224   12.7   27.4   23.1
                                       Influenza A virus
        INA493212   Orthomyxoviridae   (A/chicken/Italy/13307/99(H7N1))      1723   16.3   27.6   23.2
                                       Influenza A virus
        INA491720   Orthomyxoviridae   (A/chicken/Italy/13474/99(H7N1))      1723   16.3   27.6   23.2
                                       Influenza A virus
        INA493214   Orthomyxoviridae   (A/chicken/Italy/13489/99(H7N1))      1723   16.3   28.1   23.2
                                       Influenza A virus
        INA493215   Orthomyxoviridae   (A/chicken/Italy/267/00(H7N1))        1723   16.8   28.1   23.1




                                                                 Page 8
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


                                       Influenza A virus
        AF194169    Orthomyxoviridae (A/Chicken/Italy/312/97(H5N2))                 1734   16.1   26.0   24.5
                                       Influenza A virus
        AF194990    Orthomyxoviridae   (A/Chicken/Italy/367/97(H5N2))               1732   16.7   26.0   24.3
                                       Influenza A virus
        INA580353   Orthomyxoviridae   (A/chicken/Italy/445/99(H7N1))               1711   16.4   27.2   23.3
                                       Influenza A virus (A/chicken/Italy/4575/99
        INA493469   Orthomyxoviridae   (H7N1))                                      1683   14.6   27.9   22.5
                                       Influenza A virus
        INA305306   Orthomyxoviridae   (A/chicken/Italy/8/98(H5N2))                 1731   16.8   25.1   24.4
                                       Influenza A virus
        AF194992    Orthomyxoviridae   (A/Chicken/Italy/9097/97(H5N9))              1679   12.8   24.4   23.2
                                       Influenza A virus
        AF461509    Orthomyxoviridae   (A/Chicken/Jiangsu/1/99(H9N2))               1683   21.4   22.0   23.8
                                       Influenza A virus
        AF461510    Orthomyxoviridae   (A/Chicken/Jiangsu/2/98(H9N2))               1683   22.9   24.7   23.1
                                       Influenza A virus (A/chicken/Jiangsu/JS-
        AY364228    Orthomyxoviridae   1/2002(H9N2))                                1683   23.8   23.8   23.1
                                       Influenza A virus (A/Chicken/Korea/25232-
        AF156440    Orthomyxoviridae 006/96(H9N2))                                  2253   21.5   23.3   26.0
                                       Influenza A virus (A/Chicken/Korea/38349-
        AF156439    Orthomyxoviridae p96323/96(H9N2))                               2259   20.6   21.5   25.7
                                       Influenza A virus
        AF203787    Orthomyxoviridae   (A/Chicken/Korea/MS96/96(H9N2))              1539    9.4   18.8   24.2
                                       Influenza A virus
        AF461518    Orthomyxoviridae   (A/Chicken/Liaoning/1/00(H9N2))              1683   25.3   23.2   23.4
                                       Influenza A virus
        AF461519    Orthomyxoviridae   (A/Chicken/Liaoning/2/00(H9N2))              1683   25.3   23.5   23.6
                                       Influenza A virus
        AF536697    Orthomyxoviridae   (A/Chicken/Liaoning/99(H9N2))                1478   21.0   18.6   22.7
                                       Influenza A virus
                                       (A/Chicken/Mexico/26654-1374/94
        AF098586    Orthomyxoviridae   (H5N2))                                      2273   13.9   27.5   25.4
                                       Influenza A virus
                                       (A/Chicken/Mexico/26654-1374/97
        AF098556    Orthomyxoviridae   (H5N2))                                      1318   12.5   23.1   24.7
                                       Influenza A virus
                                       (A/Chicken/Mexico/26654-1734/94
        AF098613    Orthomyxoviridae   (H5N2))                                      2165   12.0   27.9   23.7
                                       Influenza A virus (A/Chicken/New
        AY240916    Orthomyxoviridae   Jersey/20621/99(H7N2))                       1670   15.6   28.7   22.9
                                       Influenza A virus (A/Chicken/New
        AY240892    Orthomyxoviridae   York/12273-11/99(H7N3))                      1697   17.1   25.9   21.9
                                       Influenza A virus (A/Chicken/New
        AF072384    Orthomyxoviridae   York/13142-5/94 (H7N2))                      1700   16.8   25.9   22.6
                                       Influenza A virus (A/Chicken/New
        AF072388    Orthomyxoviridae   York/13833-7/95 (H7N2))                      1700   17.1   25.0   22.2
                                       Influenza A virus (A/Chicken/New
        AY254120    Orthomyxoviridae   York/19542-5/95 (H7N2))                      1433   15.7   23.0   25.0
                                       Influenza A virus (A/Chicken/New
        AY254124    Orthomyxoviridae   York/3112-1/95 (H7N2))                       1432   15.7   24.1   24.9
                                       Influenza A virus (A/Chicken/New
        AY254125    Orthomyxoviridae   York/3202-7/96 (H7N2))                       1386   14.1   22.7   22.9
                                       Influenza A virus (A/Chicken/New
        AY254126    Orthomyxoviridae   York/4447-7/94 (H7N2))                       1432   16.4   23.7   25.1
                                       Influenza A virus (A/Chicken/New
        AF072396    Orthomyxoviridae   York/6777-3/97(H7N2))                        1681   17.3   28.0   22.8
                                       Influenza A virus (A/Chicken/New
        AF072393    Orthomyxoviridae   York/8030-2/96 (H7N2))                       1696   17.1   26.8   23.4
                                       Influenza A virus (A/Chicken/NJ/118555-
        AY254108    Orthomyxoviridae   2/01(H7N2))                                  1384   15.2   26.4   23.3
                                       Influenza A virus (A/chicken/NJ/118878-
        AY240884    Orthomyxoviridae   5/01(H7N2))                                  1670   15.6   27.5   22.5
                                       Influenza A virus (A/chicken/NJ/150383-
        AY240885    Orthomyxoviridae   7/02(H7N2))                                  1670   15.3   28.1   23.0
                                       Influenza A virus (A/chicken/NJ/15086-
        AY300950    Orthomyxoviridae   3/94(H7N3))                                  1338   13.5   22.8   24.0
                                       Influenza A virus (A/chicken/NJ/151244-
        AY240886    Orthomyxoviridae   18/02(H7N2))                                 1670   15.0   28.1   22.9




                                                                  Page 9
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus (A/chicken/NJ/15814-
        AY240887    Orthomyxoviridae 9/99(H7N2))                                 1674   15.8   28.7   23.3
                                       Influenza A virus
        AY240918    Orthomyxoviridae   (A/chicken/NJ/15827/99(H7N2))             1669   15.6   28.8   23.2
                                       Influenza A virus (A/Chicken/NJ/16224-
        AY254112    Orthomyxoviridae   6/99(H7N2))                               1384   16.6   23.1   23.3
                                       Influenza A virus
        AY240915    Orthomyxoviridae   (A/chicken/NJ/17206/99(H7N2))             1670   16.8   29.0   22.6
                                       Influenza A virus (A/Chicken/NJ/30739-
        AY254113    Orthomyxoviridae   6/00(H7N2))                               1384   15.9   26.0   22.8
                                       Influenza A virus
        AY240888    Orthomyxoviridae   (A/chicken/NJ/608/02(H7N2))               1670   15.3   28.1   22.9
                                       Influenza A virus (A/chicken/NJ/9777-
        AY240889    Orthomyxoviridae   7/98(H7N2))                               1653   16.3   29.6   22.5
                                       Influenza A virus (A/chicken/NY/119055-
        AY240890    Orthomyxoviridae   7/01(H7N2))                               1670   15.6   27.8   23.0
                                       Influenza A virus (A/chicken/NY/119256-
        AY240891    Orthomyxoviridae   7/01(H7N2))                               1670   15.9   29.0   23.1
                                       Influenza A virus (A/chicken/NY/1387-
        AY240893    Orthomyxoviridae   8/98(H7N2))                               1673   17.3   28.1   23.1
                                       Influenza A virus (A/chicken/NY/1398-
        AY240919    Orthomyxoviridae   6/99(H7N2))                               1670   16.2   27.8   22.5
                                       Influenza A virus (A/chicken/NY/14714-
        AY240921    Orthomyxoviridae   2/99(H7N2))                               1694   17.7   26.3   23.0
                                       Influenza A virus (A/chicken/NY/14714-
        AY240894    Orthomyxoviridae   9/99(H7N3))                               1697   19.2   25.6   22.6
                                       Influenza A virus (A/Chicken/NY/14858-
        AY240907    Orthomyxoviridae   12/99(H7N2))                              1673   15.2   28.7   22.9
                                       Influenza A virus (A/chicken/NY/21586-
        AY240895    Orthomyxoviridae   8/99(H7N2))                               1673   15.5   29.3   22.8
                                       Influenza A virus (A/chicken/NY/22409-
        AY240896    Orthomyxoviridae   4/99(H7N2))                               1673   15.5   27.5   23.2
                                       Influenza A virus (A/chicken/NY/30749-
        AY240897    Orthomyxoviridae   3/00(H7N2))                               1673   14.3   29.6   22.3
                                       Influenza A virus (A/chicken/NY/34173-
        AY240920    Orthomyxoviridae   3/99(H7N2))                               1670   15.3   29.9   23.2
                                       Influenza A virus
        AY240917    Orthomyxoviridae   (A/chicken/NY/3572/98(H7N2))              1670   16.8   27.2   22.8
                                       Influenza A virus (A/chicken/NY/6031-
        AY240898    Orthomyxoviridae   19/98(H7N2))                              1654   17.5   28.1   22.9
                                       Influenza A virus
        AY240899    Orthomyxoviridae   (A/chicken/PA/143586/01(H7N2))            1661   14.8   28.3   23.0
                                       Influenza A virus (A/chicken/PA/149092-
        AY240900    Orthomyxoviridae   1/02(H7N2))                               1670   18.0   27.2   23.1
                                       Influenza A virus
        AY240901    Orthomyxoviridae   (A/chicken/PA/9701027/97(H7N2))           1667   18.0   27.3   23.3
                                       Influenza A virus
        AY240902    Orthomyxoviridae   (A/chicken/PA/9701524/97(H7N2))           1666   18.6   27.0   23.3
                                       Influenza A virus
        AY254132    Orthomyxoviridae   (A/chicken/PA/9701527/97(H7N2))           1386   16.6   23.4   22.7
                                       Influenza A virus
        AY240903    Orthomyxoviridae   (A/chicken/PA/9701530/97(H7N2))           1667   18.0   27.0   22.9
                                       Influenza A virus
        AY240904    Orthomyxoviridae   (A/chicken/PA/9800896/98(H7N2))           1667   18.0   27.3   22.7
                                       Influenza A virus
        AY240905    Orthomyxoviridae   (A/chicken/PA/9801289/98(H7N2))           1666   18.0   27.6   22.9
                                       Influenza A virus
        INA91395    Orthomyxoviridae   (A/Chicken/Pakistan/2/99(H9N2))           2342   21.1   23.1   24.5
                                       Influenza A virus
        AF202226    Orthomyxoviridae   (A/chicken/Pakistan/447/95(H7N3))         1741   19.0   27.9   23.8
                                       Influenza A virus
        AF202230    Orthomyxoviridae   (A/chicken/Pakistan/CR2/95(H7N3))         1741   19.2   28.1   23.5
                                       Influenza A virus
                                       (A/Chicken/Pennsylvania/11767-
        AF072395    Orthomyxoviridae   1/97(H7N2))                               1673   17.0   28.4   23.0
                                       Influenza A virus
                                       (A/Chicken/Pennsylvania/13552-1/98
        AF072398    Orthomyxoviridae   (H7N2))                                   1680   17.9   27.7   22.9
                                       Influenza A virus
        FLAPOT84H   Orthomyxoviridae   (A/chicken/Potsdam/4705/84 (H2N2))        1773   13.0   25.7   25.7




                                                                Page 10
Endoh et al. Supplement for Table 5                        ProbUniqueVirus



                                       Influenza A virus
        AF098588    Orthomyxoviridae (A/Chicken/Puebla/14585-622/94 (H5N2))        2273   13.2   27.3   25.7
                                       Influenza A virus (A/Chicken/Puebla/8623-
        AF098587    Orthomyxoviridae   607/94(H5N2))                               2273   13.2   27.3   25.8
                                       Influenza A virus
        AF202231    Orthomyxoviridae   (A/chicken/Queensland/667/95(H7N3))         1737   11.2   28.5   23.0
                                       Influenza A virus
                                       (A/Chicken/Queretaro/14588-19/94
        AF098559    Orthomyxoviridae   (H5N2))                                     1318   12.5   23.1   24.7
                                       Influenza A virus
                                       (A/Chicken/Queretaro/14588-
        AF098589    Orthomyxoviridae   19/95(H5N2))                                2273   13.9   27.5   25.4
                                       Influenza A virus
        INFAHA12    Orthomyxoviridae   (A/chicken/Scotland/59(H5N1))               1768   15.0   25.5   24.9
                                       Influenza A virus
        AF461520    Orthomyxoviridae   (A/Chicken/Shandong/1/98(H9N2))             1683   25.3   21.7   23.4
                                       Influenza A virus
        AF461521    Orthomyxoviridae   (A/Chicken/Shandong/2/99(H9N2))             1683   26.1   21.4   23.0
                                       Influenza A virus
        AF536698    Orthomyxoviridae   (A/Chicken/Shandong/98(H9N2))               1478   18.3   20.0   23.7
                                       Influenza A virus
        AY281745    Orthomyxoviridae   (A/Chicken/Shanghai/1/02(H9N2))             1683   26.7   22.0   23.9
                                       Influenza A virus
        AF461522    Orthomyxoviridae   (A/Chicken/Shanghai/2/99(H9N2))             1683   22.3   22.9   23.2
                                       Influenza A virus
        AF461523    Orthomyxoviridae   (A/Chicken/Shanghai/3/00(H9N2))             1683   22.0   22.0   24.4
                                       Influenza A virus
        AY083840    Orthomyxoviridae   (A/Chicken/Shanghai/3/01(H9N2))             1683   21.4   22.6   23.3
                                       Influenza A virus
        AY083841    Orthomyxoviridae   (A/Chicken/Shanghai/4/01(H9N2))             1683   21.4   22.3   23.2
                                       Influenza A virus (A/Chicken/Shanghai/4-
        AF461524    Orthomyxoviridae   1/01(H9N2))                                 1683   22.9   22.3   24.3
                                       Influenza A virus (A/Chicken/Shanghai/4-
        AF461525    Orthomyxoviridae   2/01(H9N2))                                 1683   22.9   22.0   24.3
                                       Influenza A virus
        AY253751    Orthomyxoviridae   (A/Chicken/Shanghai/F/98(H9N2))             2341   15.0   23.8   24.0
                                       Influenza A virus
        AY043014    Orthomyxoviridae   (A/Chicken/Shaoguan/13/98(H9N2))            1539   23.4   21.4   24.0
                                       Influenza A virus (A/chicken/Taiwan/7-
        AF262210    Orthomyxoviridae   5/99(H6N1))                                 2341   16.9   22.7   24.0
                                       Influenza A virus
        AF461526    Orthomyxoviridae   (A/Chicken/Tianjing/1/96(H9N2))             1683   22.9   23.8   24.2
                                       Influenza A virus
        AF461527    Orthomyxoviridae   (A/Chicken/Tianjing/2/96(H9N2))             1683   23.5   23.8   24.1
                                       Influenza A virus (A/chicken/TX/167280-
        AY296085    Orthomyxoviridae   4/02(H5N3))                                 1691   23.4   27.8   23.7
                                       Influenza A virus
        AY240906    Orthomyxoviridae   (A/chicken/VA/32/02(H7N2))                  1670   14.4   27.5   23.1
                                       Influenza A virus
        AF202227    Orthomyxoviridae   (A/chicken/Victoria/1/92(H7N3))             1737   12.4   28.2   22.8
                                       Influenza A virus
        AY268949    Orthomyxoviridae   (A/chicken/Wangcheng/4/2001(H9N2))          1558   10.9   23.1   25.9
                                       Influenza A virus
        AF461528    Orthomyxoviridae   (A/Chicken/Yunnan/1/99(H9N2))               1683   24.7   23.2   24.2
                                       Influenza A virus
        AF461529    Orthomyxoviridae   (A/Chicken/Yunnan/2/00(H9N2))               1683   24.7   22.3   24.2
        ORINPB2     Orthomyxoviridae   Influenza A virus (A/Chile/1/83/(H1N1))     2341   17.5   25.6   24.0
        AF242181    Orthomyxoviridae   Influenza A virus (A/China)                 1404    7.1   21.4   25.4
                                       Influenza A virus
        AY297141    Orthomyxoviridae   (A/Chonnam/07/2002(H1N1))                   1452   19.6   28.9   24.3
                                       Influenza A virus
        AY297143    Orthomyxoviridae   (A/Chonnam/18/2002(H1N1))                   1458   19.9   28.8   23.7
                                       Influenza A virus
        AY310410    Orthomyxoviridae   (A/Chonnam/19/2002(H1N1))                   1458   19.9   28.1   24.1
                                       Influenza A virus
        AY310412    Orthomyxoviridae   (A/Chonnam/51/2002(H1N1))                   1443   20.8   29.1   24.2
                                       Influenza A virus (A/chukka/Hong
        INA410501   Orthomyxoviridae   Kong/FY295/00(H6N1))                        2280   20.2   23.9   24.6
                                       Influenza A virus (A/chukka/Hong
        INA410553   Orthomyxoviridae   Kong/NT261/00(H6N1))                        1497    6.3   20.4   24.9




                                                                Page 11
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


                                       Influenza A virus (A/chukkar/MN/14591-
        AY300926    Orthomyxoviridae 7/98(H5N2))                                    1410   16.3   26.6   26.0
                                       Influenza A virus
        AY296073    Orthomyxoviridae   (A/chukkar/NY/51375/00(H5N2))                1735   20.2   29.1   24.9
                                       Influenza A virus
        AY297150    Orthomyxoviridae   (A/Chungbuk/50/2002(H1N1))                   1425   18.9   28.8   24.1
        AF203008    Orthomyxoviridae   Influenza A virus (A/ck/Korea/ms96/96)       1683   21.1   17.8   23.1
                                       Influenza A virus (A/common iora
        AF202228    Orthomyxoviridae   /Singapore/F89/95(H7N1))                     1732   13.3   26.3   23.0
                                       Influenza A virus
        AF202241    Orthomyxoviridae   (A/conure/England/1234/94(H7N1))             1766   15.0   26.3   22.9
                                       Influenza A virus
        AF202249    Orthomyxoviridae   (A/conure/England/766/94(H7N1))              1711   15.2   27.2   23.8
                                       Influenza A virus
        AF533732    Orthomyxoviridae   (A/Cordoba/V185/98(H3N2))                    1466   22.9   22.2   24.8
                                       Influenza A virus
        AF533741    Orthomyxoviridae   (A/Cordoba/V391/98(H3N2))                    1466   22.9   22.2   24.8
                                       Influenza A virus
        AF533742    Orthomyxoviridae   (A/Cordoba/V584/98(H3N2))                    1466   22.9   22.2   25.0
                                       Influenza A virus
        AF533740    Orthomyxoviridae   (A/Cordoba/V651/98(H3N2))                    1466   22.9   22.2   24.8
                                       Influenza A virus (A/Cottbus/42/88
        IVI252131   Orthomyxoviridae   (H3N2))                                      1759   14.8   26.2   23.6
                                       Influenza A virus (A/curlew sandpiper/Hong
        INA427301   Orthomyxoviridae   Kong/208/89(H10N5))                          1497    9.0   23.7   24.5
                                       Influenza A virus
        IVI518095   Orthomyxoviridae   (A/Denmark/40/2000(H1N1))                    1458   19.9   28.1   24.1
                                       Influenza A virus
        INA457957   Orthomyxoviridae   (A/Denmark/41/2000(H3N2))                    1439   24.0   23.6   23.8
                                       Influenza A virus
        INA457932   Orthomyxoviridae   (A/Denmark/511/98(H3N2))                     1465   25.6   22.2   24.8
                                       Influenza A virus
        AF091309    Orthomyxoviridae   (A/duck/Alberta/35/76(H1N1))                 1777   16.9   26.7   24.3
                                       Influenza A virus
        FLAHAH12N   Orthomyxoviridae   (A/duck/Alberta/60/76(H12N5))                1695   15.9   23.6   23.1
                                       Influenza A virus (A/Duck/Anyang/AVL-
        AF468840    Orthomyxoviridae   1/2001(H5N1))                                2280   16.0   20.7   23.9
                                       Influenza A virus
        IAHEMAC     Orthomyxoviridae   (A/duck/Australia/341/83(H15N8))             1762   16.2   24.7   24.2
                                       Influenza A virus
        AF091312    Orthomyxoviridae   (A/duck/Australia/749/80(H1N1))              1777   17.4   25.0   25.4
                                       Influenza A virus (A/duck/Bavaria/1/77
        AF091313    Orthomyxoviridae   (H1N1))                                      1777   13.8   26.2   25.4
                                       Influenza A virus
        AF290436    Orthomyxoviridae   (A/Duck/Czechoslovakia/56(H4N6))             1714   18.7   24.8   25.3
                                       Influenza A virus
        FLAHAH11N   Orthomyxoviridae   (A/duck/England/56(H11N6))                   1698   10.3   24.1   24.0
        FLAGDR72H   Orthomyxoviridae Influenza A virus (A/duck/GDR/72 (H2N9))       1773   11.6   28.5   23.9
                                       Influenza A virus (A/Duck/Ho Chi
        AF290443    Orthomyxoviridae   Minh/014/78(H5N3))                           1659   15.1   26.8   23.5
                                       Influenza A virus
        AB125931    Orthomyxoviridae   (A/duck/Hokkaido/13/00(H9N2))                1497   22.7   17.0   23.4
                                       Influenza A virus
        AB125930    Orthomyxoviridae   (A/duck/Hokkaido/26/99(H9N2))                1499   25.7   16.3   23.1
                                       Influenza A virus
        AB125927    Orthomyxoviridae   (A/duck/Hokkaido/31/97(H9N2))                1477   24.4   16.2   23.4
                                       Influenza A virus
        AB125928    Orthomyxoviridae   (A/duck/Hokkaido/49/98(H9N2))                1492   23.5   20.1   24.9
                                       Influenza A virus (A/Duck/Hokkaido/8/80
        AF079571    Orthomyxoviridae   (H3N8))                                      1497    8.7   22.7   25.7
                                       Influenza A virus
        AB125929    Orthomyxoviridae   (A/duck/Hokkaido/9/99(H9N2))                 1501   25.0   16.3   23.6
                                       Influenza A virus (A/duck/Hong Kong/1037-
        INA410531   Orthomyxoviridae   1/98 (H6N2))                                 1701   25.3   28.2   23.0
                                       Influenza A virus (A/duck/Hong Kong/1037-
        INA410532   Orthomyxoviridae   2/98 (H6N2))                                 1701   25.6   26.5   23.5
                                       Influenza A virus (A/duck/Hong Kong/1037-
        INA410533   Orthomyxoviridae   3/98 (H6N2))                                 1701   26.2   26.5   23.4
                                       Influenza A virus (A/duck/Hong Kong/1037-
        INA410534   Orthomyxoviridae   4/98 (H6N2))                                 1701   26.2   27.0   23.5




                                                                 Page 12
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus (A/duck/Hong
        INA410540   Orthomyxoviridae Kong/108/76 (H6N5))                     1701   23.5   27.0   23.6
                                       Influenza A virus (A/duck/Hong
        INA410541   Orthomyxoviridae   Kong/134/77 (H6N2))                   1701   23.2   25.6   23.8
                                       Influenza A virus (A/duck/Hong
        AY206671    Orthomyxoviridae   Kong/147/77(H9N6))                    1683   20.8   20.2   23.5
                                       Influenza A virus (A/duck/Hong
        AF156382    Orthomyxoviridae   Kong/168/77(H9N2))                    1661   17.5   21.7   23.0
                                       Influenza A virus (A/duck/Hong
        INA410542   Orthomyxoviridae   Kong/175/77(H6N1))                    1701   23.2   26.5   23.9
                                       Influenza A virus (A/duck/Hong
        INA410543   Orthomyxoviridae   Kong/182/77 (H6N9))                   1701   23.5   25.0   24.0
                                       Influenza A virus (A/duck/Hong
        INA410544   Orthomyxoviridae   Kong/202/77(H6N1))                    1701   20.6   26.5   23.3
                                       Influenza A virus (A/duck/Hong
        INA410545   Orthomyxoviridae   Kong/221/77 (H6N8))                   1701   22.0   25.0   23.5
                                       Influenza A virus (A/duck/Hong
        FLADUCK14   Orthomyxoviridae   Kong/24/76(H3N2))                     1341   20.1   25.0   25.4
                                       Influenza A virus (A/duck/Hong
        FLADUCK15   Orthomyxoviridae   Kong/245/77(H3N2))                    1341   20.5   24.2   24.8
                                       Influenza A virus (A/duck/Hong
        FLAHNG78H   Orthomyxoviridae   Kong/273/78 (H2N2))                   1772   14.1   28.2   24.0
                                       Influenza A virus (A/duck/Hong
        AF523440    Orthomyxoviridae   Kong/289/78(H9N2))                    1533   15.7   25.4   23.9
                                       Influenza A virus (A/Duck/Hong
        AY059525    Orthomyxoviridae   Kong/2986.1/2000(H5N1))               2277   15.8   22.4   24.1
                                       Influenza A virus (A/duck/Hong
        INA410509   Orthomyxoviridae   Kong/3096/99(H6N2))                   2277   12.7   22.2   24.4
                                       Influenza A virus (A/duck/Hong
        INA410536   Orthomyxoviridae   Kong/3174/99 (H6N2))                  1701   25.9   27.3   23.3
                                       Influenza A virus (A/duck/Hong
        INA410609   Orthomyxoviridae   Kong/31741/99 (H6N2))                 1512   21.2   22.2   24.4
                                       Influenza A virus (A/duck/Hong
        INA410529   Orthomyxoviridae   Kong/323/98 (H6N2))                   1701   25.6   27.3   23.2
                                       Influenza A virus (A/duck/Hong
        INA410530   Orthomyxoviridae   Kong/324/98 (H6N2))                   1701   25.6   27.3   23.0
                                       Influenza A virus (A/duck/Hong
        INA410537   Orthomyxoviridae   Kong/3461/99(H6N1))                   1701   18.2   28.8   22.6
                                       Influenza A virus (A/duck/Hong
        INA410538   Orthomyxoviridae   Kong/3600/99 (H6N2))                  1701   25.6   27.3   23.3
                                       Influenza A virus (A/duck/Hong
        AY206674    Orthomyxoviridae   Kong/366/78(H9N2))                    1683   22.0   18.4   22.1
                                       Influenza A virus (A/Duck/Hong
        AY075033    Orthomyxoviridae   Kong/380.5/2001(H5N1))                1748   18.9   20.9   23.6
                                       Influenza A virus (A/duck/Hong
        AY206673    Orthomyxoviridae   Kong/448/78(H9N2))                    1683   22.0   20.8   22.9
                                       Influenza A virus (A/duck/Hong
        AY206679    Orthomyxoviridae   Kong/552/79(H9N2))                    1683   21.1   21.1   23.1
                                       Influenza A virus (A/Duck/Hong
        AF509038    Orthomyxoviridae   Kong/573.4/01 (H5N1))                 1500   19.0   20.0   23.1
                                       Influenza A virus (A/duck/Hong
        AY206680    Orthomyxoviridae   Kong/610/79(H9N2))                    1683   20.8   20.2   23.2
                                       Influenza A virus (A/duck/Hong
        AY206678    Orthomyxoviridae   Kong/644/79(H9N2))                    1677   21.2   18.8   23.7
                                       Influenza A virus (A/Duck/Hong
        AF509194    Orthomyxoviridae   Kong/646.3/01 (H5N1))                 1485   12.8   23.6   23.0
                                       Influenza A virus (A/duck/Hong
        AY206672    Orthomyxoviridae   Kong/702/79(H9N2))                    1683   21.1   20.5   23.5
                                       Influenza A virus (A/duck/Hong
        INA410539   Orthomyxoviridae   Kong/73/76(H6N1))                     1701   29.4   26.2   21.9
                                       Influenza A virus (A/duck/Hong
        AF156383    Orthomyxoviridae   Kong/784/79(H9N2))                    1671   20.6   20.0   23.7
                                       Influenza A virus (A/duck/Hong
        AF523423    Orthomyxoviridae   Kong/86/76(H9N2))                     1560    9.0   25.3   24.9
                                       Influenza A virus (A/Duck/Hong
        AF250473    Orthomyxoviridae   Kong/P185/97(H3N8))                   1497    8.0   19.4   24.0
                                       Influenza A virus (A/Duck/Hong
        AF098582    Orthomyxoviridae   Kong/p46/97 (H5N1))                   2273   19.8   23.5   24.5
                                       Influenza A virus (A/Duck/Hong
        AF250474    Orthomyxoviridae   Kong/P54/97(H11N9))                   1497    8.4   18.7   24.0




                                                                 Page 13
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus (A/Duck/Hong
        AF250470    Orthomyxoviridae Kong/T25/97(H11N8))                          1497    7.7   18.7   24.5
                                       Influenza A virus (A/Duck/Hong
        AF250471    Orthomyxoviridae   Kong/T37/97(H11N8))                        1497    8.0   19.0   24.5
                                       Influenza A virus (A/Duck/Hong
        AY059476    Orthomyxoviridae   Kong/ww381/2000(H5N1))                     1704   18.2   23.8   24.3
                                       Influenza A virus (A/Duck/Hong
        AY059477    Orthomyxoviridae   Kong/ww382/2000(H5N1))                     1704   18.2   23.8   24.3
                                       Influenza A virus (A/Duck/Hong
        AY059478    Orthomyxoviridae   Kong/ww461/2000(H5N1))                     1704   18.5   23.8   24.4
                                       Influenza A virus (A/Duck/Hong
        AY059479    Orthomyxoviridae   Kong/ww487/2000(H5N1))                     1704   17.9   23.8   24.4
                                       Influenza A virus (A/duck/Hong
        AF156433    Orthomyxoviridae   Kong/Y280/97(H9N2))                        2246   20.7   22.3   24.4
                                       Influenza A virus (A/Duck/Hong
        AF098583    Orthomyxoviridae   Kong/y283/97 (H5N1))                       2273   19.4   24.6   24.3
                                       Influenza A virus (A/duck/Hong
        AF156434    Orthomyxoviridae   Kong/Y439/97(H9N2))                        2260   17.0   22.6   24.8
                                       Influenza A virus (A/duck/Malaysia/F119-
        AF303057    Orthomyxoviridae   3/97(H5N3))                                1761   19.3   27.5   24.8
                                       Influenza A virus (A/duck/ME/151895-
        AY296079    Orthomyxoviridae   7A/02(H5N2))                               1691   19.8   26.6   25.1
                                       Influenza A virus
        AF098597    Orthomyxoviridae   (A/Duck/Nanchang/662/98 (H4N6))            2228   18.2   20.2   24.9
                                       Influenza A virus
        AY233387    Orthomyxoviridae   (A/duck/NC/91347/01(H1N2))                 2330   16.1   23.6   25.2
                                       Influenza A virus (A/duck/NJ/117228-
        AY296077    Orthomyxoviridae   7/01(H5N2))                                1691   18.9   26.6   24.5
                                       Influenza A virus
        AY296080    Orthomyxoviridae   (A/duck/NY/185502/02(H5N2))                1704   20.0   27.0   25.1
                                       Influenza A virus
        AY296081    Orthomyxoviridae   (A/duck/NY/186875/02(H5N2))                1705   18.8   27.3   25.3
                                       Influenza A virus (A/duck/NY/191255-
        AY296086    Orthomyxoviridae   59/02(H5N8))                               1705   19.9   27.0   25.2
                                       Influenza A virus (A/duck/NY/191255-
        AY296082    Orthomyxoviridae   79/02(H5N2))                               1705   20.5   26.7   25.1
                                       Influenza A virus (A/duck/NY/44018-
        AY296071    Orthomyxoviridae   1/00(H5N2))                                1732   21.4   28.3   24.5
                                       Influenza A virus (A/duck/NY/44018-
        AY296072    Orthomyxoviridae   2/00(H5N2))                                1735   20.5   28.2   24.6
                                       Influenza A virus (A/Duck/Ohio/118C/93
        AF250361    Orthomyxoviridae   (H1N1))                                    1410   15.2   20.9   27.5
                                       Influenza A virus (A/Duck/Ohio/175/86
        AF250358    Orthomyxoviridae   (H1N1))                                    1410   21.3   21.3   26.9
                                       Influenza A virus (A/Duck/Ohio/194/86
        AF250360    Orthomyxoviridae   (H1N1))                                    1410   15.2   20.6   26.2
                                       Influenza A virus (A/Duck/Ohio/30/86
        AF250359    Orthomyxoviridae   (H1N1))                                    1410   19.5   21.3   26.3
                                       Influenza A virus
        AF523447    Orthomyxoviridae   (A/Duck/Shantou/1042/00(H9N2))             1593   13.8   24.5   25.6
                                       Influenza A virus
        AF523446    Orthomyxoviridae   (A/Duck/Shantou/1043/00(H9N2))             1701   13.8   25.3   25.2
                                       Influenza A virus
        AF523461    Orthomyxoviridae   (A/Duck/Shantou/1588/00(H9N1))             1692   12.7   22.8   26.8
                                       Influenza A virus
        AF523442    Orthomyxoviridae   (A/Duck/Shantou/1605/01(H9N2))             1467   11.9   26.6   24.3
                                       Influenza A virus
        AF523450    Orthomyxoviridae   (A/Duck/Shantou/1796/00(H9N2))             1689   14.2   23.4   25.5
                                       Influenza A virus
        AF523455    Orthomyxoviridae   (A/Duck/Shantou/1881/00(H9N2))             1554   15.1   24.5   25.9
                                       Influenza A virus
        AF523462    Orthomyxoviridae   (A/Duck/Shantou/2030/00(H9N1))             1647   12.4   22.8   26.7
                                       Influenza A virus
        AF523448    Orthomyxoviridae   (A/Duck/Shantou/2088/01(H9N2))             1743   12.6   23.5   26.1
                                       Influenza A virus
        AF523428    Orthomyxoviridae   (A/Duck/Shantou/2102/00(H9N2))             1497   12.7   27.7   25.4
                                       Influenza A virus
        AF523452    Orthomyxoviridae   (A/Duck/Shantou/2134/00(H9N2))             1677   14.9   23.9   25.5
                                       Influenza A virus
        AF523451    Orthomyxoviridae   (A/Duck/Shantou/2143/00(H9N2))             1689   14.8   24.3   25.5




                                                                Page 14
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus
        AF523372    Orthomyxoviridae (A/Duck/Shantou/2144/00(H9N2))                1686   29.7   21.6   22.8
                                       Influenza A virus
        AF523449    Orthomyxoviridae   (A/Duck/Shantou/830/00(H9N2))               1725   11.9   24.9   25.4
                                       Influenza A virus
        AF503469    Orthomyxoviridae   (A/Egypt/21181/2001(H1N2))                  1410   27.7   22.3   24.9
        INA457944   Orthomyxoviridae Influenza A virus (A/Egypt/84/2001(H1N2))     1428   26.6   21.4   25.2
        INA457943   Orthomyxoviridae Influenza A virus (A/Egypt/96/2002(H1N2))     1449   27.3   22.1   24.4
        INA489848   Orthomyxoviridae Influenza A virus (A/England/1/02(H1N2))      1407   26.3   21.7   25.1
        INA489849   Orthomyxoviridae Influenza A virus (A/England/57/02(H1N2))     1407   25.9   22.0   24.7
                                       Influenza A virus
        INA489846   Orthomyxoviridae   (A/England/627/01(H1N2))                    1407   26.3   21.3   25.2
                                       Influenza A virus
        INA489847   Orthomyxoviridae   (A/England/691/01(H1N2))                    1407   26.3   22.0   24.9
                                       Influenza A virus
                                       (A/England/939/69(H3N2) x
        INA564806   Orthomyxoviridae   (A/PR/8/34(H1N1))                           2341   15.7   25.7   24.6
        INA489850   Orthomyxoviridae Influenza A virus (A/England/97/02(H1N2))     1407   25.9   22.0   24.7
                                       Influenza A virus (A/Environment/Hong
        AF216741    Orthomyxoviridae   Kong/437-10/99 (H5N1))                      2280   14.6   22.5   24.2
                                       Influenza A virus (A/Environment/Hong
        AF216717    Orthomyxoviridae   Kong/437-4/99 (H5N1))                       2280   14.6   22.5   24.2
                                       Influenza A virus (A/Environment/Hong
        AF216725    Orthomyxoviridae   Kong/437-6/99 (H5N1))                       2280   14.7   22.9   24.3
                                       Influenza A virus (A/Environment/Hong
        AF216733    Orthomyxoviridae   Kong/437-8/99 (H5N1))                       2280   14.6   22.5   24.2
                                       Influenza A virus (A/environment/NY/5626-
        AY300928    Orthomyxoviridae   1/98(H5N2))                                 1410   16.7   25.5   26.2
                                       Influenza A virus (A/environment/NY/5626-
        AY300930    Orthomyxoviridae   17/98(H5N2))                                1410   16.7   25.5   26.2
                                       Influenza A virus (A/environment/NY/5626-
        AY300929    Orthomyxoviridae   2/98(H5N2))                                 1410   16.7   25.5   26.2
                                       Influenza A virus
        EFLAC64HA   Orthomyxoviridae   (A/equine/C.Detroit/1/64(H7N7))             1761   19.6   27.5   24.6
                                       Influenza A virus
        EFLAC63HA   Orthomyxoviridae   (A/equine/Cambridge/1/63(H7N7))             1761   21.0   31.2   23.1
                                       Influenza A virus
        EFLAC73HA   Orthomyxoviridae   (A/equine/Cambridge/1/73(H7N7))             1761   19.6   27.8   24.3
                                       Influenza A virus
        EFLAD64HA   Orthomyxoviridae   (A/equine/Detroit/1/64(H7N7))               1761   19.0   25.8   24.4
                                       Influenza A virus
        IVAH691     Orthomyxoviridae   (A/equine/Ibadan/6/91(H3N8))                1762   16.7   23.3   24.7
                                       Influenza A virus
        IVAH991     Orthomyxoviridae   (A/equine/Ibadan/9/91(H3N8))                1762   15.9   23.0   23.8
                                       Influenza A virus
        IA58195     Orthomyxoviridae   (A/equine/Kentucky/1/81(H3N8))              1763   17.6   23.0   24.0
                                       Influenza A virus
        EFLAL64HA   Orthomyxoviridae   (A/equine/lexington/1/66(H7N7))             1761   19.6   27.8   24.7
                                       Influenza A virus
        EFLAL73HA   Orthomyxoviridae   (A/equine/London/1416/73(H7N7))             1761   19.6   27.5   24.4
                                       Influenza A virus
        EFLAN77HA   Orthomyxoviridae   (A/equine/Newmarket/1/77(H7N7))             1761   18.7   27.0   24.8
                                       Influenza A virus
        EFLAP56HA   Orthomyxoviridae   (A/equine/prague/56(H7N7))                  1761   20.4   31.2   23.1
                                       Influenza A virus
        AY383756    Orthomyxoviridae   (A/equine/Santiago/77(H7N7))                1713   20.1   27.4   24.5
                                       Influenza A virus
        AY383755    Orthomyxoviridae   (A/equine/Santiago/85(H3N8))                1698   17.4   24.1   24.3
                                       Influenza A virus (A/equine/Sao
        EFLAS76HA   Orthomyxoviridae   Paulo/1/76(H7N7))                           1761   19.6   28.4   23.9
                                       Influenza A virus
        EIVHAEG     Orthomyxoviridae   (A/equine/Suffolk/89(H3N8))                 1742   16.9   23.0   25.0
                                       Influenza A virus
        EFLAS72HA   Orthomyxoviridae   (A/equine/Switzerland/137/72(H7N7))         1761   19.6   27.5   24.2
                                       Influenza A virus (A/fairy
        AF202229    Orthomyxoviridae   bluebird/Singapore/F92/94(H7N1))            1732   13.9   27.7   24.0




                                                                Page 15
Endoh et al. Supplement for Table 5                         ProbUniqueVirus



        INA564805   Orthomyxoviridae Influenza A Virus (A/Fiji/15899/83(H1N1))     2341   16.9   26.1   24.6
        INA289702   Orthomyxoviridae Influenza A virus (A/Fiji/15899/83)           1779   16.0   22.8   22.9
                                        Influenza A virus
        IVI518100   Orthomyxoviridae (A/Finland/131/2002(H1N1))                    1429   20.3   28.3   23.7
                                        Influenza A virus
        AY377552    Orthomyxoviridae    (A/Finland/133/90(H3N2))                   1302   18.4   22.3   23.9
                                        Influenza A virus
        AY377551    Orthomyxoviridae    (A/Finland/144/90(H3N2))                   1302   19.6   21.9   24.4
                                        Influenza A virus
        AY377561    Orthomyxoviridae    (A/Finland/189/92(H3N2))                   1302   19.6   21.5   25.2
                                        Influenza A virus
        AY377554    Orthomyxoviridae    (A/Finland/206/92(H3N2))                   1302   19.6   20.4   24.5
                                        Influenza A virus
        AY377558    Orthomyxoviridae    (A/Finland/208/92(H3N2))                   1302   19.6   20.0   24.7
                                        Influenza A virus
        AY377559    Orthomyxoviridae    (A/Finland/211/92(H3N2))                   1302   19.6   20.0   24.7
                                        Influenza A virus
        AY377560    Orthomyxoviridae    (A/Finland/215/92(H3N2))                   1302   19.6   20.4   24.7
                                        Influenza A virus
        AY377556    Orthomyxoviridae    (A/Finland/219/92(H3N2))                   1302   19.6   20.7   24.7
                                        Influenza A virus
        AY377555    Orthomyxoviridae    (A/Finland/231/92(H3N2))                   1302   19.6   20.7   24.7
                                        Influenza A virus
        AY377557    Orthomyxoviridae    (A/Finland/232/92(H3N2))                   1302   19.6   20.7   24.7
                                        Influenza A virus
        AY377562    Orthomyxoviridae    (A/Finland/239/92(H3N2))                   1302   19.6   21.9   25.2
                                        Influenza A virus
        AY377553    Orthomyxoviridae    (A/Finland/246/92(H3N2))                   1302   19.6   20.4   24.9
                                        Influenza A virus
        AY377549    Orthomyxoviridae    (A/Finland/247/92(H3N2))                   1302   19.6   22.3   25.3
                                        Influenza A virus
        AY377548    Orthomyxoviridae    (A/Finland/263/93(H3N2))                   1302   18.8   21.5   25.1
                                        Influenza A virus
        AY377550    Orthomyxoviridae    (A/Finland/274/93(H3N2))                   1302   18.4   21.9   24.9
                                        Influenza A virus
        AY377564    Orthomyxoviridae    (A/Finland/276/93(H3N2))                   1302   17.7   21.5   25.0
                                        Influenza A virus
        AY377566    Orthomyxoviridae    (A/Finland/278/93(H3N2))                   1302   17.7   21.5   25.0
                                        Influenza A virus
        AY377567    Orthomyxoviridae    (A/Finland/280/93(H3N2))                   1302   17.7   21.5   25.0
                                        Influenza A virus
        AY377565    Orthomyxoviridae    (A/Finland/292/93(H3N2))                   1302   18.4   21.5   24.8
                                        Influenza A virus
        AY377563    Orthomyxoviridae    (A/Finland/300/93(H3N2))                   1302   17.3   21.1   24.7
                                        Influenza A virus
        AY377568    Orthomyxoviridae    (A/Finland/364/95(H3N2))                   1302   19.6   23.0   25.0
                                        Influenza A virus
        INA457965   Orthomyxoviridae    (A/Finland/620/99(H3N2))                   1465   23.9   22.5   24.8
                                        Influenza A virus (A/Fort Monmouth/1/47-
        IAPB247MA   Orthomyxoviridae    MA(H1N1))                                  2341   16.3   26.4   25.5
                                        Influenza A virus (A/Fort
        ORFLAFW5    Orthomyxoviridae    Warren/1/50(H1N1))                         1565   12.1   23.6   23.8
        AF202237    Orthomyxoviridae Influenza A virus (A/FPV/Egypt/45(H7N1))      1661   21.1   25.6   23.7
                                        Influenza A virus
        ORFLAF01    Orthomyxoviridae    (A/FPV/Rostock/34(H7N1))                   1565   12.1   21.7   25.1
        INA457941   Orthomyxoviridae    Influenza A virus (A/Genoa/5/98(H3N2))     1465   23.2   24.2   24.4
                                        Influenza A virus
        AF144301    Orthomyxoviridae    (A/Goose/Guangdong/1/96(H5N1))             2341   14.5   22.6   24.2
                                        Influenza A virus
        AY035888    Orthomyxoviridae    (A/goose/Guangdong/3/1997(H5N1))           2319   14.7   21.3   24.2
                                        Influenza A virus (A/goose/Hong
        INA410546   Orthomyxoviridae    Kong/17/77 (H6N4))                         1701   21.5   26.2   23.5
                                        Influenza A virus (A/Goose/Hong
        AY075030    Orthomyxoviridae    Kong/3014.5/2000(H5N1))                    1748   20.0   20.3   24.1
                                        Influenza A virus (A/Goose/Hong
        AY059529    Orthomyxoviridae    Kong/3014.8/2000(H5N1))                    2277   15.4   22.8   24.0
                                        Influenza A virus (A/Goose/Hong
        AF398417    Orthomyxoviridae    Kong/385.3/2000(H5N1))                     1704   17.6   21.4   23.8




                                                                 Page 16
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus (A/Goose/Hong
        AF398424    Orthomyxoviridae Kong/385.5/2000(H5N1))                        2253   14.6   21.3   23.7
                                       Influenza A virus (A/Goose/Hong
        AF509036    Orthomyxoviridae   Kong/76.1/01 (H5N1))                        1674   18.5   20.9   23.6
                                       Influenza A virus (A/Goose/Hong
        INA410526   Orthomyxoviridae   Kong/W217/97(H6N9))                         1701   26.2   27.9   24.0
                                       Influenza A virus (A/goose/Hong
        INA410527   Orthomyxoviridae   Kong/W222/97 (H6N7))                        1701   28.2   27.0   22.9
                                       Influenza A virus (A/Goose/Hong
        AF098584    Orthomyxoviridae   Kong/w355/97 (H5N1))                        2273   19.8   23.8   24.5
                                       Influenza A virus (A/goose/Hong
        INA410528   Orthomyxoviridae   Kong/W375/97 (H6N2))                        1701   27.6   26.7   22.8
                                       Influenza A virus (A/Goose/Hong
        AF509037    Orthomyxoviridae   Kong/ww100/01 (H5N1))                       1650   16.1   20.3   23.9
                                       Influenza A virus (A/Goose/Hong
        AY059520    Orthomyxoviridae   Kong/ww26/2000(H5N1))                       2277   14.3   24.6   24.6
                                       Influenza A virus (A/Goose/Hong
        AY059521    Orthomyxoviridae   Kong/ww28/2000(H5N1))                       2277   14.3   23.9   24.7
                                       Influenza A virus (A/Goose/Hong
        AY059480    Orthomyxoviridae   Kong/ww491/2000(H5N1))                      1704   17.9   23.5   24.4
                                       Influenza A virus
        AF156389    Orthomyxoviridae   (A/Goose/Minnesota/5733/80(H9N2))           1207   21.5   18.6   22.2
                                       Influenza A virus (A/goose/NJ/8600-
        AY240922    Orthomyxoviridae   3/98(H7N2))                                 1670   16.5   27.8   22.5
        AF316811    Orthomyxoviridae Influenza A virus (A/Greece/1/97 (H3N2))      1336   22.1   23.2   24.6
                                       Influenza A virus (A/Greece/106/98
        AF316807    Orthomyxoviridae   (H3N2))                                     1362   22.8   22.8   25.6
                                       Influenza A virus (A/Greece/109/99
        AF316808    Orthomyxoviridae   (H3N2))                                     1399   22.2   23.2   25.6
                                       Influenza A virus (A/Greece/132/99
        AF316809    Orthomyxoviridae   (H3N2))                                     1348   24.5   21.5   24.3
        AF316816    Orthomyxoviridae Influenza A virus (A/Greece/18/98 (H3N2))     1394   23.3   23.7   25.6
                                       Influenza A virus
        AY043029    Orthomyxoviridae   (A/Guangzhou/333/99(H9N2))                  2302   12.8   24.3   24.9
                                       Influenza A virus (A/guinea fowl/Hong
        AY206676    Orthomyxoviridae   Kong/WF10/99(H9N2))                         1683   26.4   20.5   23.9
                                       Influenza A virus (A/Guinea
        AF194991    Orthomyxoviridae   Fowl/Italy/330/97(H5N2))                    1749   16.6   26.0   24.8
                                       Influenza A virus (A/Guinea
        AF072394    Orthomyxoviridae   Fowl/Pennsylvania/7777-1/96(H7N2))          1667   16.5   28.2   23.2
                                       Influenza A virus (A/guinea/NJ/3070/91
        FLANJ91HA   Orthomyxoviridae   (H2N2))                                     1773   14.7   24.5   24.1
                                       Influenza A virus
        AY254137    Orthomyxoviridae   (A/guineafowl/MA/148081/02(H7N2))           1385   15.2   26.4   22.7
                                       Influenza A virus
        AY240908    Orthomyxoviridae   (A/guineafowl/MA/148081-11/02(H7N2))        1672   15.6   27.5   23.0
                                       Influenza A virus (A/guineafowl/New
        AY254139    Orthomyxoviridae   York/13820-3/97(H7N2))                      1433   16.4   23.7   25.1
                                       Influenza A virus (A/guineafowl/NJ/13246-
        AY240909    Orthomyxoviridae   9/98(H7N2))                                 1670   17.7   28.1   23.4
                                       Influenza A virus (A/gull/Italy/692-
        AF202248    Orthomyxoviridae   2/93(H7N2))                                 1732   13.9   24.0   22.5
                                       Influenza A virus
        FLAHAH13N   Orthomyxoviridae   (A/Gull/Maryland/704/77(H13N6))             1701   19.4   25.9   24.1
                                       Influenza A virus (A/gull/MD/19/77
        FLAMD77HA   Orthomyxoviridae   (H2N8))                                     1772   13.3   24.5   23.9
                                       Influenza A virus
        AY297151    Orthomyxoviridae   (A/Gwangju/55/2002(H1N1))                   1431   21.0   29.0   24.2
                                       Influenza A virus
        AY297152    Orthomyxoviridae   (A/Gwangju/57/2002(H1N1))                   1446   18.7   28.4   24.1
                                       Influenza A virus
        AY297153    Orthomyxoviridae   (A/Gwangju/58/2002(H1N1))                   1434   19.2   27.9   24.1
                                       Influenza A virus
        AY297147    Orthomyxoviridae   (A/Gwangju/90/2002(H1N1))                   1446   20.4   28.7   24.3
                                       Influenza A virus (A/herring
        FLADE88HA   Orthomyxoviridae   gull/DE/677/88 (H2N8))                      1773   11.8   27.4   25.4
                                       Influenza A virus (A/Hong
        AF348173    Orthomyxoviridae   Kong/1/68(H3N2))                            2341   15.6   24.0   24.4




                                                                Page 17
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus (A/Hong Kong/1035/98
        AF386778    Orthomyxoviridae (H1N1))                                    1775   19.2   21.8   23.4
                                       Influenza A virus (A/Hong
        INA404630   Orthomyxoviridae   Kong/1073/99(H9N2))                      2341   17.0   24.6   24.2
                                       Influenza A virus (A/Hong
        INA404631   Orthomyxoviridae   Kong/1074/99(H9N2))                      2341   17.1   25.1   24.4
                                       Influenza A virus (A/Hong Kong/1131/98
        AF386775    Orthomyxoviridae   (H1N1))                                  1775   17.5   20.8   23.8
                                       Influenza A virus (A/Hong Kong/1134/98
        AF386781    Orthomyxoviridae   (H1N1))                                  1775   19.4   21.5   23.1
                                       Influenza A virus (A/Hong
        AY035588    Orthomyxoviridae   Kong/1143/99(H3N2))                      1762   13.9   23.9   24.8
                                       Influenza A virus (A/Hong
        AY035589    Orthomyxoviridae   Kong/1144/99(H3N2))                      1762   13.3   25.6   24.7
                                       Influenza A virus (A/Hong
        AY035590    Orthomyxoviridae   Kong/1179/99(H3N2))                      1762   13.3   24.7   24.5
                                       Influenza A virus (A/Hong
        AY035591    Orthomyxoviridae   Kong/1180/99(H3N2))                      1762   13.3   25.3   25.0
                                       Influenza A virus (A/Hong
        AY035592    Orthomyxoviridae   Kong/1182/99(H3N2))                      1762   13.3   25.3   25.0
                                       Influenza A virus (A/Hong
        INA404633   Orthomyxoviridae   Kong/156/97(H5N1))                       2341   14.2   25.0   24.4
                                       Influenza A virus (A/Hong
        IVI293920   Orthomyxoviridae   Kong/1774/99(H3N2))                      2341   17.1   20.5   24.5
                                       Influenza A virus (A/Hong
        INA457933   Orthomyxoviridae   Kong/1789/2000(H3N2))                    1441   26.0   22.2   24.8
                                       Influenza A virus (A/Hong
        INA457934   Orthomyxoviridae   Kong/2/2000(H3N2))                       1465   25.3   22.5   24.4
                                       Influenza A virus (A/Hong
        INA457931   Orthomyxoviridae   Kong/221/99(H3N2))                       1465   25.3   22.5   24.6
                                       Influenza A virus (A/Hong
        AF258526    Orthomyxoviridae   Kong/427/98(H1N1))                       2341   18.0   23.5   23.9
                                       Influenza A virus (A/Hong
        IVI518101   Orthomyxoviridae   Kong/437/2002(H1N1))                     1403   18.5   26.7   24.9
                                       Influenza A virus (A/Hong
        AF258527    Orthomyxoviridae   Kong/470/97(H1N1))                       2341   18.6   25.5   24.0
                                       Influenza A virus (A/Hong
        AF258837    Orthomyxoviridae   Kong/481/97(H5N1))                       2341   15.4   25.2   24.2
                                       Influenza A virus (A/Hong
        AF258838    Orthomyxoviridae   Kong/482/97(H5N1))                       2341   14.2   24.2   24.4
                                       Influenza A Virus (A/Hong
        AF258839    Orthomyxoviridae   Kong/483/97(H5N1))                       2341   15.8   24.3   24.2
                                       Influenza A virus (A/Hong
        INA404632   Orthomyxoviridae   Kong/485/97(H5N1))                       2341   20.3   24.3   23.8
                                       Influenza A virus (A/Hong
        AF258840    Orthomyxoviridae   Kong/486/97(H5N1))                       2341   15.1   24.6   24.5
                                       Influenza A virus (A/Hong
        AF102657    Orthomyxoviridae   Kong/488/97(H5N1))                       1350   15.6   21.1   26.0
                                       Influenza A virus (A/Hong
        AF102665    Orthomyxoviridae   Kong/491/97(H5N1))                       1350   14.8   22.2   25.5
                                       Influenza A virus (A/Hong
        AF258841    Orthomyxoviridae   Kong/497/97(H3N2))                       2341   15.9   25.3   24.0
                                       Influenza A virus (A/Hong
        AF258842    Orthomyxoviridae   Kong/498/97(H3N2))                       2341   17.4   25.1   23.9
                                       Influenza A virus (A/Hong
        AF102666    Orthomyxoviridae   Kong/503/97(H5N1))                       1350   15.2   22.2   25.2
                                       Influenza A virus (A/Hong
        AF102659    Orthomyxoviridae   Kong/507/97(H5N1))                       1350   15.6   21.1   26.1
                                       Influenza A virus (A/Hong
        AF102669    Orthomyxoviridae   Kong/514/97(H5N1))                       1350   11.5   23.0   25.3
                                       Influenza A virus (A/Hong
        AF296752    Orthomyxoviridae   Kong/516/97(H5N1))                       1351   14.4   22.9   25.8
                                       Influenza A Virus (A/Hong
        AF258843    Orthomyxoviridae   Kong/532/97(H5N1))                       2341   15.7   24.9   24.3
                                       Influenza A virus (A/Hong
        AF258844    Orthomyxoviridae   Kong/538/97(H5N1))                       2341   15.3   25.4   24.3
                                       Influenza A virus (A/Hong
        AF258845    Orthomyxoviridae   Kong/542/97(H5N1))                       2341   15.6   24.3   24.2
                                       Influenza A virus (A/Hong
        INA457936   Orthomyxoviridae   Kong/6/99(H3N2))                         1465   25.3   22.5   23.9




                                                                Page 18
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


                                       Influenza A virus (A/Hong
        IVI518102   Orthomyxoviridae Kong/747/2001(H1N1))                     1352   17.0   26.6   24.2
                                       Influenza A virus
        AF258846    Orthomyxoviridae   (A/HongKong/97/98(H5N1))               2341   15.1   24.8   24.4
                                       Influenza A virus
        INA307599   Orthomyxoviridae   (A/human/Montreal/MTL103/00(H3N2))     1410   23.0   23.0   25.3
                                       Influenza A virus
        INA307621   Orthomyxoviridae   (A/human/Montreal/MTL152/00(H3N2))     1410   23.4   22.3   25.2
                                       Influenza A virus
        INA307627   Orthomyxoviridae   (A/human/Montreal/MTL169/00(H3N2))     1410   25.2   22.7   25.6
                                       Influenza A virus
        INA307607   Orthomyxoviridae   (A/human/Montreal/MTL172/00(H3N2))     1410   23.4   23.4   25.2
                                       Influenza A virus
        INA307613   Orthomyxoviridae   (A/human/Montreal/MTL20/00(H3N2))      1410   25.2   22.3   25.3
                                       Influenza A virus
        INA307617   Orthomyxoviridae   (A/human/Montreal/MTL29/00(H3N2))      1410   25.2   22.7   25.6
                                       Influenza A virus
        INA307618   Orthomyxoviridae   (A/human/Montreal/MTL30/00(H3N2))      1410   25.2   22.3   25.5
                                       Influenza A virus
        INA307620   Orthomyxoviridae   (A/human/Montreal/MTL327/00(H3N2))     1410   23.0   22.3   25.5
                                       Influenza A virus
        INA307616   Orthomyxoviridae   (A/human/Montreal/MTL45/00(H3N2))      1410   25.2   22.3   25.7
                                       Influenza A virus
        INA307615   Orthomyxoviridae   (A/human/Montreal/MTL50/00(H3N2))      1410   25.2   23.0   25.5
                                       Influenza A virus
        INA307622   Orthomyxoviridae   (A/human/Montreal/MTL500/00(H3N2))     1410   23.0   23.0   25.3
                                       Influenza A virus
        INA307614   Orthomyxoviridae   (A/human/Montreal/MTL512/00(H3N2))     1410   25.2   22.3   25.4
                                       Influenza A virus
        INA307628   Orthomyxoviridae   (A/human/Montreal/MTL516/00(H3N2))     1410   25.2   22.3   25.5
                                       Influenza A virus
        INA307623   Orthomyxoviridae   (A/human/Montreal/MTL63/00(H3N2))      1410   23.0   23.0   25.3
                                       Influenza A virus
        INA307602   Orthomyxoviridae (A/human/Montreal/MTL63149/00(H3N2))     1410   23.4   22.3   25.6
                                       Influenza A virus
        INA307604   Orthomyxoviridae (A/human/Montreal/MTL63274/00(H3N2))     1410   23.8   23.8   25.4
                                       Influenza A virus
        INA307629   Orthomyxoviridae (A/human/Montreal/MTL63286/00(H3N2))     1410   23.4   23.8   25.2
                                       Influenza A virus
        INA307626   Orthomyxoviridae (A/human/Montreal/MTL63446/00(H3N2))     1410   22.7   23.4   24.9
                                       Influenza A virus
        INA307601   Orthomyxoviridae (A/human/Montreal/MTL63748/00(H3N2))     1410   23.0   22.3   25.3
                                       Influenza A virus
        INA307600   Orthomyxoviridae (A/human/Montreal/MTL63816/00(H3N2))     1410   22.7   24.1   25.4
                                       Influenza A virus
        INA307606   Orthomyxoviridae (A/human/Montreal/MTL63963/00(H3N2))     1410   24.5   25.2   25.4
                                       Influenza A virus
        INA307625   Orthomyxoviridae (A/human/Montreal/MTL71034/00(H3N2))     1410   23.0   23.0   25.3
                                       Influenza A virus
        INA307603   Orthomyxoviridae (A/human/Montreal/MTL71044/00(H3N2))     1410   23.4   23.4   25.2
                                       Influenza A virus
        INA307608   Orthomyxoviridae (A/human/Montreal/MTL71045/00(H3N2))     1410   23.4   23.4   25.2
                                       Influenza A virus
        INA307609   Orthomyxoviridae (A/human/Montreal/MTL71046/00(H3N2))     1410   26.6   22.7   26.0
                                       Influenza A virus
        INA307610   Orthomyxoviridae (A/human/Montreal/MTL71213/00(H3N2))     1410   23.0   23.0   25.3
                                       Influenza A virus
        INA307611   Orthomyxoviridae (A/human/Montreal/MTL71973/00(H3N2))     1410   23.0   23.4   25.2




                                                                   Page 19
Endoh et al. Supplement for Table 5                         ProbUniqueVirus



                                       Influenza A virus
        INA307624   Orthomyxoviridae (A/human/Montreal/MTL71976/00(H3N2))          1410   23.0   23.0   25.5
                                       Influenza A virus
        INA307619   Orthomyxoviridae (A/human/Montreal/MTL72692/00(H3N2))          1410   23.4   23.0   25.4
                                       Influenza A virus
        INA307612   Orthomyxoviridae (A/human/Montreal/MTL72709/00(H3N2))          1410   25.2   22.3   25.3
                                       Influenza A virus
        INA307605   Orthomyxoviridae   (A/human/Montreal/MTL8/00(H3N2))            1410   21.3   22.0   25.0
                                       Influenza A virus
        AF503470    Orthomyxoviridae   (A/India/66139/2001(H1N2))                  1410   26.2   22.0   25.0
                                       Influenza A virus
        AF503471    Orthomyxoviridae   (A/India/77251/2001(H1N2))                  1410   25.9   21.6   24.5
        AF494254    Orthomyxoviridae   Influenza A virus (A/India/80(H1N1))        1413   18.4   25.5   24.6
                                       Influenza A virus
        INA457964   Orthomyxoviridae   (A/Ireland/10586/99(H3N2))                  1465   21.8   23.2   24.6
        FLAH2N2E    Orthomyxoviridae   Influenza A virus (A/Izumi/5/65(H2N2))      1773   13.8   28.5   26.0
        FLAH2N2F    Orthomyxoviridae   Influenza A virus (A/Izumi/5/65(R)(H2N2))   1773   13.8   28.8   26.0
        AB101671    Orthomyxoviridae Influenza A virus (A/Japan/305/57(H2N2))      1410   19.1   26.2   25.4
                                       Influenza A virus
        IVI518096   Orthomyxoviridae   (A/Johannesburg/159/97(H1N1))               1459   17.1   27.8   23.6
                                       Influenza A virus
        INA457940   Orthomyxoviridae   (A/Johannesburg/29/98(H3N2))                1465   22.5   23.2   24.8
                                       Influenza A virus
        INA457946   Orthomyxoviridae   (A/Johannesburg/33/94(H3N2))                1465   23.2   22.5   24.3
                                       Influenza A virus
        IVI518099   Orthomyxoviridae   (A/Johannesburg/82/96(H1N1))                1459   17.8   28.1   24.9
        AB056699    Orthomyxoviridae   Influenza A virus (A/Kayano/57(H2N2))       1773   15.5   27.9   25.2
        FLAKOR68H   Orthomyxoviridae Influenza A virus (A/Korea/426/68(H2N2))      1773   14.9   27.6   25.3
                                       Influenza A virus (A/Krasnodar/101/59
        FLAKRA59H   Orthomyxoviridae   (H2N2))                                     1773   15.5   29.6   25.0
                                       Influenza A virus
        FLAHUMAN1   Orthomyxoviridae   (A/Kumamoto/1/65(H3N2))                     1341   19.0   22.0   26.2
                                       Influenza A virus
        INA457963   Orthomyxoviridae   (A/Latvia/1097/2000(H3N2))                  1465   22.5   22.9   24.6
                                       Influenza A virus (A/Laughing gull/New
        AF116201    Orthomyxoviridae   Jersey/75/85 (H2N9))                        1723   17.7   25.8   24.1
                                       Influenza A virus (A/Leningrad/134/17/57
        FLAPB2PR2   Orthomyxoviridae   (H2N2))                                     2341   17.5   26.9   24.9
                                       Influenza A virus (A/Leningrad/134/47/57
        FLAPB2PRO   Orthomyxoviridae   (H2N2))                                     2349   17.7   27.2   25.0
                                       Influenza A virus (A/Leningrad/134/57
        FLAPB2PR1   Orthomyxoviridae   (H2N2))                                     2341   17.5   26.9   24.8
                                       Influenza A virus
        INA457956   Orthomyxoviridae   (A/Lyon/1242/2000(H3N2))                    1443   25.6   23.6   25.2
        INA316063   Orthomyxoviridae Influenza A Virus (A/Lyon/2573/98(H3N2))      1447   23.2   22.5   25.2
                                       Influenza A virus
        IVI518103   Orthomyxoviridae   (A/Lyon/651/2001(H1N1))                     1318   19.3   25.4   24.6
                                       Influenza A virus
        AF202250    Orthomyxoviridae   (A/macaw/England/626/80(H7N7))              1710   12.6   21.9   21.9
                                       Influenza A virus (A/Mallard
        AF100181    Orthomyxoviridae   Duck/Alberta/211/85 (H6N2))                 1653   21.5   24.2   22.7
                                       Influenza A virus (A/Mallard
        AF310988    Orthomyxoviridae   Duck/Alberta/357/84(H8N4))                  1226   26.5   19.6   22.8
                                       Influenza A virus (A/Mallard
        AF512941    Orthomyxoviridae   duck/PA/10218/84(H5N2))                     1695   19.3   26.4   25.6
                                       Influenza A virus
        AF457663    Orthomyxoviridae   (A/Mallard/Alberta/206/96(H6N8))            1703   22.3   28.5   23.1
                                       Influenza A virus
        FLAALB88H   Orthomyxoviridae   (A/mallard/ALberta/353/88 (H2N3))           1772   17.5   27.1   23.9
                                       Influenza A virus
        AF457669    Orthomyxoviridae   (A/Mallard/Alberta/4/94(H6N8))              1702   27.6   27.0   22.8
                                       Influenza A virus (A/mallard/MT/Y61
        FLAMT61HA   Orthomyxoviridae   (H2N2))                                     1773   14.1   27.1   25.6
                                       Influenza A virus (A/mallard/NY/6750/78
        FLANY78HA   Orthomyxoviridae   (H2N2))                                     1773   15.8   24.8   23.9




                                                                 Page 20
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


                                       Influenza A virus (A/mallard/Ontario/56/76
        FLAONT76H   Orthomyxoviridae (H2N3))                                        1772   16.4   24.5   23.3
                                       Influenza A virus (A/mallard/Potsdam/178-
        FLAPOT83H   Orthomyxoviridae   4/83 (H2N2))                                 1773   14.1   26.5   25.6
                                       Influenza A virus
        AF091311    Orthomyxoviridae   (A/mallard/Tennessee/11464/85 (H1N1))        1777   18.0   25.6   23.7
        AY122326    Orthomyxoviridae   Influenza A virus (A/Marton/43(H1N1))        1411   19.5   25.2   23.5
        AB101675    Orthomyxoviridae Influenza A virus (A/Memphis/1/71(H3N2))       1410   21.6   22.0   25.9
                                       Influenza A virus (A/Memphis/14/96-
        AY282758    Orthomyxoviridae   E(H1N1))                                     1743   17.8   22.1   23.6
                                       Influenza A virus (A/Memphis/14/96-
        AY282759    Orthomyxoviridae   E1(H1N1))                                    1743   17.8   22.1   23.6
                                       Influenza A virus (A/Memphis/14/96-
        AY282756    Orthomyxoviridae   M(H1N1))                                     1743   17.8   22.1   23.5
                                       Influenza A virus (A/Memphis/14/96-
        AY282757    Orthomyxoviridae   M1(H1N1))                                    1743   17.8   22.4   23.5
                                       Influenza A virus
        AY271794    Orthomyxoviridae   (A/Memphis/31/98(H3N2))                      1701   13.5   24.4   24.5
                                       Influenza A virus
        AF533748    Orthomyxoviridae   (A/Montevideo/2722/98(H3N2))                 1466   25.2   22.5   24.7
                                       Influenza A virus
        AF533749    Orthomyxoviridae   (A/Montevideo/2728/98(H3N2))                 1466   22.9   22.2   24.7
                                       Influenza A virus
        AF533750    Orthomyxoviridae   (A/Montevideo/2775/98(H3N2))                 1466   22.9   22.2   24.8
                                       Influenza A virus
        IVI518094   Orthomyxoviridae   (A/Morocco/69/2001(H1N1))                    1367   20.8   27.4   24.5
        INA457966   Orthomyxoviridae Influenza A virus (A/Moscow/10/99(H3N2))       1465   24.6   22.5   24.7
                                       Influenza A virus
        AB101672    Orthomyxoviridae   (A/Murakami/4/64(H2N2))                      1410   20.2   23.8   26.6
                                       Influenza A virus
        AB019354    Orthomyxoviridae   (A/Nagasaki/48/95(H3N2))                     1762   15.6   23.6   23.7
                                       Influenza A virus
        AB019355    Orthomyxoviridae   (A/Nagasaki/76/98(H3N2))                     1762   13.9   25.3   24.4
                                       Influenza A virus
        AB019356    Orthomyxoviridae   (A/Nagasaki/93/98(H3N2))                     1762   13.9   25.0   24.3
                                       Influenza A virus
        AB019357    Orthomyxoviridae   (A/Nagasaki/97/95(H3N2))                     1762   16.5   24.4   23.6
                                       Influenza A virus
        INA457945   Orthomyxoviridae   (A/Nanchang/933/95(H3N2))                    1465   21.2   22.9   24.6
                                       Influenza A virus
        INA457958   Orthomyxoviridae   (A/Netherlands/126/2001(H3N2))               1395   24.4   23.3   25.3
                                       Influenza A virus
        AF533743    Orthomyxoviridae   (A/Neuquen/V541/98(H3N2))                    1466   22.9   22.9   25.3
                                       Influenza A virus
        AF533744    Orthomyxoviridae   (A/Neuquen/V690/98(H3N2))                    1466   22.9   22.2   24.8
                                       Influenza A virus
        AF503465    Orthomyxoviridae   (A/Nevada/5/2001(H1N2))                      1410   26.2   22.0   25.0
                                       Influenza A virus (A/New
        AY289929    Orthomyxoviridae   Caledonia/20/99(H1N1))                       1711   18.1   20.7   23.2
                                       Influenza A virus
        AF116576    Orthomyxoviridae   (A/New_York/1/18(H1N1))                      1220   23.8   22.5   24.7
        AF250363    Orthomyxoviridae   Influenza A virus (A/NJ/11/76 (H1N1))        1410   16.7   24.8   25.3
                                       Influenza A virus (A/non-
        AF202240    Orthomyxoviridae   psittacine/England-Q/1985/89(H7N7))          1711   15.8   25.7   23.1
        IAJHAMA     Orthomyxoviridae Influenza A virus (A/NT/60/68/29c(H3N2))       1765   14.2   29.2   24.3
        AF408859    Orthomyxoviridae Influenza A virus (A/NWS-G70c(H1N9))           1778   19.4   21.9   24.4
        AF408861    Orthomyxoviridae Influenza A virus (A/NWS-Mvi(H1N2))            1778   19.4   21.9   24.3
        AF408860    Orthomyxoviridae Influenza A virus (A/NWS-Tokyo(H1N2))          1778   19.4   21.9   24.5
                                       Influenza A virus
        AF503472    Orthomyxoviridae (A/Oman/16353/2001(H1N2))                      1410   26.2   21.3   25.3
        IVI518098   Orthomyxoviridae Influenza A virus (A/Oslo/734/98(H1N1))        1459   15.8   27.8   24.3
                                       Influenza A virus (A/ostrich/South
        AF202244    Orthomyxoviridae Africa/1069/91(H7N1))                          1732   13.9   24.2   23.3
                                       Influenza A virus (A/ostrich/South
        AF202253    Orthomyxoviridae   Africa/M320/96(H7N7))                        1732   15.6   23.1   23.1
                                       Influenza A virus
        AF202234    Orthomyxoviridae   (A/ostrich/Zimbabwe/222/96(H7N1))            1731   14.2   24.6   23.3




                                                                 Page 21
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus
        INA457937   Orthomyxoviridae (A/Panama/2007/99(H3N2))                     1446   23.9   23.2   24.3
                                       Influenza A virus
        AB049153    Orthomyxoviridae   (A/parakeet/Chiba/1/97(H9N2))              2280   22.1   24.1   24.5
                                       Influenza A virus
        AB049154    Orthomyxoviridae   (A/parakeet/Narita/92A/98(H9N2))           2280   21.7   24.3   24.6
                                       Influenza A virus
                                       (A/parakeet/Netherlands/267497/94(H7N1
        AF202251    Orthomyxoviridae   ))                                         1732   15.3   25.4   23.6
        AF363502    Orthomyxoviridae   Influenza A virus (A/Paris/896/97(H3N2))   1704   15.3   23.2   24.5
        AF363503    Orthomyxoviridae   Influenza A virus (A/Paris/906/97(H3N2))   1704   15.3   23.2   24.5
        AF483602    Orthomyxoviridae   Influenza A virus (A/Paris/908/97(H3N2))   2280   15.8   28.7   24.4
                                       Influenza A virus
        AF202243    Orthomyxoviridae   (A/parrot/England/1174/94(H7N1))           1732   15.9   26.6   23.2
                                       Influenza A virus (A/parrot/Northern
        AF202252    Orthomyxoviridae   Ireland/VF-73-67/73(H7N1))                 1732   12.7   24.5   23.2
                                       Influenza A virus (A/Peking
        FLAPOT85H   Orthomyxoviridae   duck/Potsdam/1689-4/85 (H2N3))             1773   14.1   26.5   24.3
        INA457935   Orthomyxoviridae   Influenza A virus (A/Perugia/5/99(H3N2))   1465   25.3   22.9   24.2
                                       Influenza A virus
        INA457962   Orthomyxoviridae   (A/Perugia/7/2000(H3N2))                   1465   22.5   22.5   24.8
                                       Influenza A virus (A/pet bird/Hong
        INA427304   Orthomyxoviridae   Kong/1559/99(H3N8))                        1701   13.8   24.7   25.0
                                       Influenza A virus (A/Pheasant/Hong
        AF509020    Orthomyxoviridae   Kong/FY155/01 (H5N1))                      1674   18.2   20.9   23.8
                                       Influenza A virus (A/pheasant/Hong
        INA427305   Orthomyxoviridae   Kong/FY294/00(H6N1))                       2280   21.3   25.4   24.9
                                       Influenza A virus (A/pheasant/Hong
        INA410500   Orthomyxoviridae   Kong/NT261/00(H6N1))                       2280   20.6   23.7   24.1
                                       Influenza A virus (A/pheasant/Hong
        INA410495   Orthomyxoviridae   Kong/SH39/99(H6N1))                        2280   20.4   25.4   24.5
                                       Influenza A virus (A/Pheasant/Hong
        AF222646    Orthomyxoviridae   Kong/SSP11/99(H9N2))                       1659   17.5   24.7   24.2
                                       Influenza A virus
        AY221589    Orthomyxoviridae (A/Pheasant/HongKong/FY155/01(H5N1))         2279   15.8   23.3   25.1
                                       Influenza A virus
                                       (A/Pheasant/HongKong/FY155/01-
        AY221588    Orthomyxoviridae   MB(H5N1))                                  2279   15.6   23.0   25.1
                                       Influenza A virus
        AY300927    Orthomyxoviridae   (A/pheasant/NJ/1355/98(H5N2))              1410   16.0   27.0   24.8
                                       Influenza A virus
        INA457938   Orthomyxoviridae   (A/Philippines/26/99(H3N2))                1465   26.6   22.9   24.0
                                       Influenza A virus (A/Pigeon/Hong
        AF222643    Orthomyxoviridae   Kong/FY6/99(H9N2))                         1659   17.2   24.7   24.3
                                       Influenza A virus (A/Pigeon/Hong
        AF509023    Orthomyxoviridae   Kong/SF215/01 (H5N1))                      1674   17.6   20.6   23.5
                                       Influenza A virus (A/Pigeon/Hong
        AF156432    Orthomyxoviridae   Kong/Y233/97(H9N2))                        2278   19.8   26.6   24.3
                                       Influenza A virus (A/Pigeon/Nanchang/9-
        AY180838    Orthomyxoviridae   058/2000(H3N3))                            1410   21.6   21.3   25.5
                                       Influenza A virus (A/Pintail
        AF310987    Orthomyxoviridae   Duck/Alberta/114/79(H8N4))                 1237   26.7   21.4   22.4
                                       Influenza A virus
        FLAPRA76H   Orthomyxoviridae   (A/Pintail/Praimoric/625/76 (H2N2))        1772   14.4   28.8   23.4
        INFLX1      Orthomyxoviridae   Influenza A virus (A/PR/8/34(H1N1))        2341   16.4   24.3   25.8
        ORIN14      Orthomyxoviridae   Influenza A virus (A/PR/8/34(HON1))        1778   16.3   20.0   23.7
                                       Influenza A virus
        AF202242    Orthomyxoviridae   (A/psittacine/Italy/1/91(H7N2))            1711   14.0   24.0   22.7
                                       Influenza A virus (A/Puerto
        AF389116    Orthomyxoviridae   Rico/8/34/Mount Sinai(H1N1))               2341   17.8   26.0   25.1
                                       Influenza A virus
        AY310411    Orthomyxoviridae   (A/Pusan/22/2002(H1N1))                    1455   19.6   28.2   24.3
                                       Influenza A virus
        AY297144    Orthomyxoviridae   (A/Pusan/23/2002(H1N1))                    1440   20.1   28.1   23.9
                                       Influenza A virus
        AY297145    Orthomyxoviridae   (A/Pusan/24/2002(H1N1))                    1449   20.0   28.3   24.2
                                       Influenza A virus
        AY297148    Orthomyxoviridae   (A/Pusan/44/2002(H1N1))                    1431   20.6   28.0   24.3




                                                                Page 22
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus
        AY297146    Orthomyxoviridae (A/Pusan/45/2002(H1N1))                        1434   18.5   27.9   24.2
                                       Influenza A virus
        AY310408    Orthomyxoviridae   (A/Pusan/46/2002(H1N1))                      1422   20.4   27.8   24.5
                                       Influenza A virus
        AY297149    Orthomyxoviridae   (A/Pusan/47/2002(H1N1))                      1437   19.8   27.5   24.3
                                       Influenza A virus (A/Quail/Arkansas/29209-
        AF156428    Orthomyxoviridae   1/93 (H9N2))                                 2237   15.6   22.8   23.6
                                       Influenza A virus (A/quail/Hong Kong/1721-
        INA410496   Orthomyxoviridae   20/99(H6N1))                                 2280   21.1   25.9   24.3
                                       Influenza A virus (A/quail/Hong Kong/1721-
        INA410497   Orthomyxoviridae   30/99(H6N1))                                 2280   21.1   25.9   24.3
                                       Influenza A virus (A/Quail/Hong
        AF222642    Orthomyxoviridae   Kong/A17/99(H9N2))                           1659   17.2   24.7   24.3
                                       Influenza A virus (A/quail/Hong
        AY206675    Orthomyxoviridae   Kong/A28945/88(H9N2))                        1683   26.7   23.5   23.5
                                       Influenza A virus (A/Quail/Hong
        AF156437    Orthomyxoviridae   Kong/AF157/92(H9N2))                         2241   18.5   22.1   24.3
                                       Influenza A virus (A/Quail/Hong
        AF156435    Orthomyxoviridae   Kong/G1/97 (H9N2))                           2253   20.4   24.4   24.1
                                       Influenza A virus (A/Quail/Hong
        AF222649    Orthomyxoviridae   Kong/NT28/99(H9N2))                          1659   11.5   24.4   25.9
                                       Influenza A virus (A/Quail/Hong
        AF509022    Orthomyxoviridae   Kong/SF203/01 (H5N1))                        1635   17.1   20.8   23.3
                                       Influenza A virus (A/quail/Hong
        INA410498   Orthomyxoviridae   Kong/SF550/00(H6N1))                         2280   20.0   24.1   24.7
                                       Influenza A virus (A/quail/Hong
        INA410499   Orthomyxoviridae   Kong/SF595/00(H6N1))                         2280   21.5   25.4   24.2
                                       Influenza A virus (A/Quail/Hong
        AF222645    Orthomyxoviridae   Kong/SSP10/99(H9N2))                         1659   17.2   24.7   24.3
                                       Influenza A virus (A/Quail/Nanchang/12-
        AY180460    Orthomyxoviridae   340/2000(H1N1))                              1775   19.2   23.1   24.2
                                       Influenza A virus (A/Quail/New
        AF072399    Orthomyxoviridae   York/13989-51/98 (H7N2))                     1706   15.2   27.5   22.7
                                       Influenza A virus
        AY240923    Orthomyxoviridae   (A/quail/NY/11430/99(H7N2))                  1694   15.1   27.2   23.1
                                       Influenza A virus
        AY254140    Orthomyxoviridae   (A/quail/NY/13989/98(H7N2))                  1385   16.6   24.2   23.4
                                       Influenza A virus
        AY240924    Orthomyxoviridae   (A/quail/PA/20304/97(H7N2))                  1694   15.9   27.2   22.7
                                       Influenza A virus
        AY254141    Orthomyxoviridae   (A/Quail/PA/20304/98(H7N2))                  1347   13.7   24.1   24.9
                                       Influenza A virus (A/Red
        AF310989    Orthomyxoviridae   Kont/Delaware/254/94(H8N4))                  1229   25.2   21.2   22.6
                                       Influenza A virus
        AF457670    Orthomyxoviridae   (A/Redhead/Alberta/291/94(H6N8))             1705   27.6   27.6   22.9
        AY122327    Orthomyxoviridae   Influenza A virus (A/Rhodes/47(H1N1))        1411   20.6   24.5   23.4
                                       Influenza A virus (A/ruddy
        AY296084    Orthomyxoviridae   turnstone/NJ/2242/00(H5N3))                  1691   21.3   26.3   24.9
                                       Influenza A virus
                                       (A/Ruddyturnstone/Delaware/106/98(H6N
        AF457668    Orthomyxoviridae   2))                                          1704   25.1   25.7   23.9
        AF533745    Orthomyxoviridae Influenza A virus (A/Salta/V793/98(H3N2))      1466   22.9   21.8   24.8
        AY297142    Orthomyxoviridae Influenza A virus (A/Seoul/11/2002(H1N1))      1452   18.9   27.9   23.6
        AY310409    Orthomyxoviridae Influenza A virus (A/Seoul/13/2002(H1N1))      1452   19.3   28.2   23.9
        AY297140    Orthomyxoviridae Influenza A virus (A/Seoul/15/2002(H1N1))      1449   19.3   28.0   23.7
        AY310407    Orthomyxoviridae Influenza A virus (A/Seoul/33/2002(H1N1))      1437   19.5   28.2   23.9
                                       Influenza A virus
        AY043015    Orthomyxoviridae   (A/Shantou/239/98(H9N2))                     1488   22.2   20.2   23.0
                                       Influenza A virus
        AY043017    Orthomyxoviridae   (A/Shaoguan/408/98(H9N2))                    1488   21.5   21.8   22.2
                                       Influenza A virus
        AY043018    Orthomyxoviridae   (A/Shaoguan/447/98(H9N2))                    1488   17.5   21.2   22.6
                                       Influenza A virus
        FLAHAH6N5   Orthomyxoviridae   (A/Shearwater/Australia/1/72(H6N5))          1701   21.2   32.9   22.6




                                                                Page 23
Endoh et al. Supplement for Table 5                          ProbUniqueVirus


                                        Influenza A virus (A/shearwater/West
        IAHEMAD     Orthomyxoviridae Australia/2576/79(H15N9))                     1762   16.5   23.6   24.2
                                        Influenza A virus
        AY289930    Orthomyxoviridae    (A/Shenzhen/227/95(H1N1))                  1689   18.7   21.3   24.1
                                        Influenza A virus
        AF457665    Orthomyxoviridae    (A/Shorebird/Delaware/127/97(H6N2))        1704   25.5   22.3   24.5
                                        Influenza A virus
        AF457664    Orthomyxoviridae    (A/Shorebird/Delaware/194/98(H6N4))        1703   25.2   23.5   24.5
                                        Influenza A virus
        AF457666    Orthomyxoviridae    (A/Shorebird/Delaware/29/94(H6N8))         1704   26.7   23.2   24.6
                                        Influenza A virus
        AF156441    Orthomyxoviridae    (A/Shorebird/Delaware/9/96 (H9N2))         2253   14.0   26.9   24.9
                                        Influenza A virus
        INA457939   Orthomyxoviridae    (A/Sichuan/346/98(H3N2))                   1465   22.9   22.9   24.8
                                        Influenza A virus (A/Silky Chicken/Hong
        AF098546    Orthomyxoviridae    Kong/p17/97 (H5N1))                        1726   18.8   22.0   24.0
                                        Influenza A virus (A/Silky Chicken/Hong
        AF509021    Orthomyxoviridae    Kong/SF189/01 (H5N1))                      1674   17.6   20.3   23.4
                                        Influenza A virus (A/Silky Chicken/Hong
        AF222651    Orthomyxoviridae    Kong/SF44/99(H9N2))                        1659   11.5   26.8   26.0
                                        Influenza A virus
        FLASIN57H   Orthomyxoviridae    (A/Singapore/1/57(H2N2))                   1773   15.5   28.5   25.0
                                        Influenza A virus
        AF503466    Orthomyxoviridae    (A/Singapore/63/2001(H1N2))                1410   26.2   21.6   25.2
                                        Influenza A virus
        AF503467    Orthomyxoviridae    (A/Singapore/66/2001(H1N2))                1410   26.2   21.6   25.2
                                        Influenza A virus
        AF503468    Orthomyxoviridae    (A/Singapore/73/2001(H1N2))                1410   26.2   21.6   25.0
                                        Influenza A virus (A/South
        INA457942   Orthomyxoviridae    Africa/1147/96(H3N2))                      1465   23.5   22.5   25.1
                                        Influenza A virus (A/South Carolina/1/18
        AF117241    Orthomyxoviridae    (H1N1))                                    1701   21.5   20.3   23.9
                                        Influenza A virus
        IVI518091   Orthomyxoviridae    (A/Stockholm/8/2001(H1N1))                 1398   20.0   25.4   24.1
        FLAH1N1D    Orthomyxoviridae    Influenza A virus (A/Suita/1/89(H1N1))     1778   18.8   24.2   23.8
        FLAH1N1E    Orthomyxoviridae Influenza A virus (A/Suita/1/89/(R)(H1N1))    1778   18.8   25.0   23.8
                                        Influenza A virus
        AY060046    Orthomyxoviridae    (A/SW/CO/17871/01(H1N2))                   1771   20.6   21.7   24.9
                                        Influenza A virus
        AY060050    Orthomyxoviridae    (A/SW/MN/16419/01(H1N2))                   1770   22.9   22.9   25.3
                                        Influenza A virus
        AY060052    Orthomyxoviridae    (A/SW/MN/17138/01(H1N2))                   1771   24.0   21.2   26.4
                                        Influenza A virus (A/SW/MN/23124-
        AY060048    Orthomyxoviridae    S/01(H1N2))                                1770   24.3   22.9   25.5
                                        Influenza A virus (A/SW/MN/23124-
        AY060047    Orthomyxoviridae    T/01(H1N2))                                1770   24.3   22.6   25.4
                                        Influenza A virus
        AY060051    Orthomyxoviridae    (A/SW/MN/34893/01(H1N2))                   1771   23.7   20.9   24.6
                                        Influenza A virus
        AY060049    Orthomyxoviridae    (A/SW/MO/1877/01(H1N2))                    1771   21.7   21.7   25.5
                                        Influenza A virus
        AY294658    Orthomyxoviridae    (A/Sw/ShanDong/1/2003(H9N2))               1683   23.5   22.6   24.1
                                        Influenza A virus
        AF225514    Orthomyxoviridae    (A/sw/Shizuoka/110/97(H3N2))               2280   16.7   29.4   24.0
                                        Influenza A virus
        AF225515    Orthomyxoviridae    (A/sw/Shizuoka/115/97(H3N2))               2280   16.7   29.2   24.2
                                        Influenza A virus
        AF225516    Orthomyxoviridae    (A/sw/Shizuoka/119/97(H3N2))               2280   16.9   29.4   24.0
                                        Influenza A virus
        AF225517    Orthomyxoviridae    (A/sw/Shizuoka/120/97(H3N2))               2280   16.9   29.4   24.0
        IVI252130   Orthomyxoviridae Influenza A virus (A/swine/Bakum/909/93)      1740   14.7   27.0   24.3
                                        Influenza A virus
        AF091316    Orthomyxoviridae    (A/swine/Belgium/1/83(H1N1))               1778   17.4   28.1   24.4
                                        Influenza A virus
        INA311455   Orthomyxoviridae    (A/swine/Belgium/220/92(H3N2))             1445   18.3   23.5   24.9
                                        Influenza A virus
        INA412691   Orthomyxoviridae    (A/swine/Belgium/74/85(H1N1))              1377   18.9   22.5   25.7
                                        Influenza A virus (A/Swine/Colorado/1/77
        AF251394    Orthomyxoviridae    (H3N2))                                    2302   17.4   28.9   24.6




                                                                  Page 24
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus
        AF268128    Orthomyxoviridae (A/Swine/Colorado/23619/99(H3N2))            1418   12.3   26.1   24.6
                                       Influenza A virus (A/Swine/Cote
        INA311458   Orthomyxoviridae   dArmor/3633/84(H3N2))                      2280   19.1   24.1   25.7
                                       Influenza A virus (A/swine/Cotes
        INA410875   Orthomyxoviridae   dArmor/1121/00(H1N1))                      1305   19.9   21.8   24.7
                                       Influenza A virus (A/swine/Cotes
        INA344021   Orthomyxoviridae   dArmor/1455/99(H1N1))                      1721   16.6   30.8   24.5
                                       Influenza A virus (A/swine/Cotes
        INA306855   Orthomyxoviridae   dArmor/1482/99(H1N1))                      1538   18.5   21.5   25.1
                                       Influenza A virus (A/swine/Cotes
        INA306856   Orthomyxoviridae   dArmor/1488/99(H1N1))                      2267   16.3   21.8   23.6
                                       Influenza A virus (A/swine/Cotes
        INA410884   Orthomyxoviridae   dArmor/1515/99(H1N1))                      1357   18.4   19.9   25.4
                                       Influenza A virus (A/swine/Cotes
        INA306864   Orthomyxoviridae   dArmor/2433/98(H1N2))                      2267   14.3   21.8   23.7
                                       Influenza A virus (A/swine/Cotes
        INA306863   Orthomyxoviridae   dArmor/604/99(H1N2))                       2268   15.9   21.4   23.0
                                       Influenza A virus (A/swine/Cotes
        INA306865   Orthomyxoviridae   dArmor/790/97(H1N2))                       2268   16.5   21.4   24.2
                                       Influenza A virus (A/swine/Cotes
        INA412694   Orthomyxoviridae   dArmor/799/00 (H1N2))                      1381   24.3   20.3   24.8
                                       Influenza A virus (A/swine/Cotes
        INA306841   Orthomyxoviridae   dArmor/800/00(H1N2))                       1846   19.8   23.0   25.5
                                       Influenza A virus
        AF085416    Orthomyxoviridae   (A/swine/England/17394/96(H1N2))           1778   18.3   25.0   22.7
                                       Influenza A virus
        AF250366    Orthomyxoviridae   (A/Swine/England/195852/92 (H1N1))         1410   21.6   20.2   25.3
                                       Influenza A virus
        AF085414    Orthomyxoviridae   (A/swine/England/438207/94(H1N2))          1778   14.3   24.5   22.8
                                       Influenza A virus
        AF085415    Orthomyxoviridae   (A/swine/England/690421/95(H1N2))          1778   15.7   23.1   22.6
                                       Influenza A virus
        AF085417    Orthomyxoviridae   (A/swine/England/72685/96(H1N2))           1778   18.6   25.0   22.8
                                       Influenza A virus
        INA311462   Orthomyxoviridae   (A/Swine/Finistere/2899/82(H1N1))          2341   15.6   23.7   22.9
                                       Influenza A virus
        INA412689   Orthomyxoviridae   (A/swine/Finistere/3616/84(H1N1))          1412   20.9   21.6   26.0
                                       Influenza A virus
        IVI293934   Orthomyxoviridae   (A/swine/Gent/70/84(H3N2))                 1467   20.1   23.2   25.0
                                       Influenza A virus (A/swine/Hokkaido/2/81
        AF091306    Orthomyxoviridae   (H1N1))                                    1778   22.2   21.4   23.3
                                       Influenza A virus (A/swine/Hong
        FLASWINE8   Orthomyxoviridae   Kong/1/76(H3N2))                           1341   23.9   21.3   25.1
                                       Influenza A virus (A/swine/Hong
        AF222817    Orthomyxoviridae   Kong/10/98(H9N2))                          2280   19.5   22.8   24.4
                                       Influenza A virus (A/swine/Hong
        FLASWIN16   Orthomyxoviridae   Kong/127/82(H3N2))                         1341   20.9   20.9   26.9
                                       Influenza A virus (A/swine/Hong
        FLASWIN11   Orthomyxoviridae   Kong/13/77(H3N2))                          1341   19.4   21.3   26.8
                                       Influenza A virus (A/swine/Hong
        FLASWIN12   Orthomyxoviridae   Kong/21/77(H3N2))                          1341   19.4   21.6   26.9
                                       Influenza A virus (A/Swine/Hong
        AF400752    Orthomyxoviridae   Kong/2405/98(H3N2))                        1646   14.0   23.1   24.5
                                       Influenza A virus (A/Swine/Hong
        AF400753    Orthomyxoviridae   Kong/2422/98(H3N2))                        1646   14.6   23.4   24.2
                                       Influenza A virus (A/Swine/Hong
        AF400754    Orthomyxoviridae   Kong/2429/98(H3N2))                        1646   14.0   23.7   24.5
                                       Influenza A virus (A/swine/Hong
        FLASWINE9   Orthomyxoviridae   Kong/3/76(H3N2))                           1341   20.5   23.1   26.2
                                       Influenza A virus (A/swine/Hong
        FLASWIN10   Orthomyxoviridae   Kong/4/76(H3N2))                           1341   23.1   22.0   24.7
                                       Influenza A virus (A/swine/Hong
        FLASWIN13   Orthomyxoviridae   Kong/72/77(H3N2))                          1341   25.7   22.0   25.4
                                       Influenza A virus (A/swine/Hong
        FLASWIN15   Orthomyxoviridae   Kong/82/78(H3N2))                          1341   23.5   20.9   25.6
                                       Influenza A virus (A/swine/Hong
        AF222816    Orthomyxoviridae   Kong/9/98(H9N2))                           2280   19.1   22.8   24.4
                                       Influenza A virus (A/swine/Ille et
        INA306866   Orthomyxoviridae   Vilaine/1455/99(H1N1))                     2261   17.2   21.9   23.8




                                                                Page 25
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus
        AF455738    Orthomyxoviridae (A/Swine/Illinois/100084/01 (H1N2))        2280   15.1   26.1   25.0
                                       Influenza A virus
        AF455737    Orthomyxoviridae   (A/Swine/Illinois/100085A/01 (H1N2))     2280   14.9   25.9   24.8
                                       Influenza A virus
        AF268124    Orthomyxoviridae   (A/Swine/Illinois/21587/99(H3N2))        1421   14.8   24.3   24.8
                                       Influenza A virus
        AF250131    Orthomyxoviridae   (A/Swine/Indiana/9K035/99 (H1N2))        2334   15.2   25.5   24.6
                                       Influenza A virus
        AF455736    Orthomyxoviridae   (A/Swine/Indiana/P12439/00 (H1N2))       2280   15.1   25.4   24.8
                                       Influenza A virus (A/swine/Iowa/15/30
        AF091308    Orthomyxoviridae   (H1N1))                                  1778   21.7   17.7   24.8
                                       Influenza A virus (A/Swine/Iowa/30
        AF250364    Orthomyxoviridae   (H1N1))                                  1410   20.2   22.3   24.8
                                       Influenza A virus (A/Swine/Iowa/533/99
        AF251418    Orthomyxoviridae   (H3N2))                                  2335   15.2   24.2   24.8
                                       Influenza A virus (A/Swine/Iowa/569/99
        AF251426    Orthomyxoviridae   (H3N2))                                  2335   15.2   24.2   24.8
                                       Influenza A virus (A/Swine/Iowa/8548-
        AF153243    Orthomyxoviridae   1/98)                                    1557   17.0   27.6   25.2
                                       Influenza A virus
        AF455735    Orthomyxoviridae   (A/Swine/Iowa/930/01(H1N2))              2280   15.1   25.0   24.7
                                       Influenza A virus
        INA311209   Orthomyxoviridae   (A/swine/Italy/1081/00(H1N2))            2184   17.9   29.1   25.0
                                       Influenza A virus (A/swine/Italy/1424-
        INA410877   Orthomyxoviridae   3/95(H1N1))                              1282   16.0   22.2   24.7
                                       Influenza A virus (A/swine/Italy/1424-
        INA410876   Orthomyxoviridae   4/95(H1N1))                              1404   16.0   22.8   24.4
                                       Influenza A virus (A/swine/Italy/1456-
        INA344008   Orthomyxoviridae   1/96(H1N1))                              1661   19.3   27.7   24.1
                                       Influenza A virus
        IVI293936   Orthomyxoviridae   (A/swine/Italy/1461/96(H3N2))            1467   18.4   25.2   24.3
                                       Influenza A virus
        INA412707   Orthomyxoviridae   (A/swine/Italy/1475/96(H3N2))            1367   19.4   24.9   25.5
                                       Influenza A virus
        INA307073   Orthomyxoviridae   (A/swine/Italy/1477/96(H3N2))            1459    6.9   22.3   24.5
                                       Influenza A virus
        INA410879   Orthomyxoviridae   (A/swine/Italy/1492/97(H1N1))            1340   21.6   22.0   25.8
                                       Influenza A virus (A/swine/Italy/1498-
        INA344019   Orthomyxoviridae   2/97(H1N1))                              1671   17.1   27.2   24.2
                                       Influenza A virus (A/swine/Italy/1509-
        INA344017   Orthomyxoviridae   6/97(H1N1))                              1671   16.8   27.8   24.7
                                       Influenza A virus
        IVI293932   Orthomyxoviridae   (A/swine/Italy/1510/98(H3N2))            1699   13.8   28.5   23.7
                                       Influenza A virus
        INA344016   Orthomyxoviridae   (A/swine/Italy/1511/98(H1N1))            1677   18.5   27.1   24.8
                                       Influenza A virus (A/Swine/Italy/1513-
        INA306861   Orthomyxoviridae   1/98(H1N1))                              2273   16.7   19.6   23.7
                                       Influenza A virus (A/swine/Italy/1513-
        INA410878   Orthomyxoviridae   8/98(H1N1))                              1310   21.8   21.4   25.2
                                       Influenza A virus
        INA306862   Orthomyxoviridae   (A/swine/Italy/1521/98(H1N2))            2268   17.0   22.7   24.1
                                       Influenza A virus
        INA311459   Orthomyxoviridae   (A/Swine/Italy/1523/98(H3N2))            2280   17.5   23.0   25.4
                                       Influenza A virus (A/swine/Italy/1654-
        INA412698   Orthomyxoviridae   1/99(H1N2))                              1210   26.0   19.8   25.6
                                       Influenza A virus
        INA412699   Orthomyxoviridae   (A/swine/Italy/1942/00(H3N2))            1335   17.6   24.3   24.9
                                       Influenza A virus
        INA306843   Orthomyxoviridae   (A/swine/Italy/2064/99(H1N2))            2250   18.4   24.2   25.4
                                       Influenza A virus
        IVI293935   Orthomyxoviridae   (A/swine/Italy/636/87(H3N2))             1467   21.8   24.2   24.4
                                       Influenza A virus (A/swine/Italy-
        AF091315    Orthomyxoviridae   Virus/671/87(H1N1))                      1777   16.3   25.6   23.6
                                       Influenza A virus
        AY129163    Orthomyxoviridae   (A/Swine/Korea/CY02/02(H1N2))            2334   15.6   24.6   24.8
                                       Influenza A virus
        INA412692   Orthomyxoviridae   (A/swine/Lot/2979/82(H1N1))              1412   20.9   22.7   26.1
                                       Influenza A virus
        AF455734    Orthomyxoviridae   (A/Swine/Minnesota/55551/00 (H1N2))      2280   14.9   26.1   24.7




                                                                Page 26
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus
        AF251434    Orthomyxoviridae (A/Swine/Minnesota/593/99 (H3N2))             2335   15.2   24.2   24.8
                                       Influenza A virus
        AF153242    Orthomyxoviridae   (A/Swine/Minnesota/9088-2/98 (H3N2))        1557   16.4   27.6   24.5
                                       Influenza A virus
        AF251410    Orthomyxoviridae   (A/Swine/Nebraska/209/98 (H3N2))            2335   15.2   24.2   24.8
                                       Influenza A virus
        AF091317    Orthomyxoviridae   (A/Swine/Netherlands/12/85(H1N1))           1776   15.2   27.3   24.3
                                       Influenza A virus
        AF091314    Orthomyxoviridae   (A/swine/Netherlands/3/80(H1N1))            1778   14.6   28.4   24.5
                                       Influenza A virus (A/swine/New
        ORAS76HA    Orthomyxoviridae   Jersey/11/76(H1N1))                         1778   17.2   20.8   24.4
                                       Influenza A virus (A/Swine/North
        AF153240    Orthomyxoviridae   Carolina/35922/98 (H3N2))                   1557   22.8   19.3   24.2
                                       Influenza A virus (A/Swine/North
        AF455733    Orthomyxoviridae   Carolina/93523/01 (H1N2))                   2280   15.1   25.9   25.3
                                       Influenza A virus (A/Swine/North
        AF455732    Orthomyxoviridae   Carolina/98225/01(H1N2))                    2280   15.4   25.9   25.3
                                       Influenza A virus
        AF268127    Orthomyxoviridae (A/Swine/NorthCarolina/16497/99(H3N2))        1424   12.3   24.6   23.6
                                       Influenza A virus
        AF385293    Orthomyxoviridae   (A/Swine/Oedenrode/7C/96(H3N2))             1554    8.0   21.9   25.1
                                       Influenza A virus
        AF455731    Orthomyxoviridae   (A/Swine/Ohio/891/01(H1N2))                 2280   14.7   25.7   24.6
                                       Influenza A virus
        AF268125    Orthomyxoviridae   (A/Swine/Oklahoma/18089/99(H3N2))           1423   14.1   24.9   24.5
                                       Influenza A virus
        AF268123    Orthomyxoviridae   (A/Swine/Oklahoma/18717/99(H3N2))           1430   15.0   24.8   24.8
                                       Influenza A virus (A/Swine/Ontario/01911-
        AF285892    Orthomyxoviridae   1/99 (H4N6))                                2341   16.0   24.5   24.7
                                       Influenza A virus (A/Swine/Ontario/01911-
        AF285883    Orthomyxoviridae   2/99 (H4N6))                                1744   14.0   22.1   22.9
                                       Influenza A virus
        AF251402    Orthomyxoviridae   (A/Swine/Ontario/41848/97 (H3N2))           2311   17.1   27.9   24.3
                                       Influenza A virus
        IVI252132   Orthomyxoviridae   (A/swine/Potsdam/35/82(H3N2))               1740   15.8   25.0   25.5
                                       Influenza A virus
        U86144      Orthomyxoviridae   (A/Swine/Quebec/192/81 (SwQc81))            1438   24.0   25.0   24.2
                                       Influenza A virus
        AF397198    Orthomyxoviridae   (A/swine/Quebec/192/81(H1N1))               1565   12.8   26.8   23.8
                                       Influenza A virus
        U86145      Orthomyxoviridae   (A/Swine/Quebec/5393/91 (SwQc91))           1438   17.7   24.3   26.1
                                       Influenza A virus
        AF397199    Orthomyxoviridae   (A/swine/Quebec/5393/91(H1N1))              1565   13.1   30.7   24.3
                                       Influenza A virus
        INA311204   Orthomyxoviridae   (A/swine/Scotland/410440/94(H1N2))          1780   16.0   30.1   24.3
                                       Influenza A virus
        INA311456   Orthomyxoviridae   (A/Swine/Taiwan/7310/70(H3N2))              1459   18.8   23.6   24.9
                                       Influenza A virus (A/Swine/Texas/4199-
        AF153241    Orthomyxoviridae   2/98(H3N2))                                 1557   16.4   27.3   24.5
                                       Influenza A virus (A/swine/United
        INA412700   Orthomyxoviridae   Kingdom/119404/91(H3N2))                    1440   24.0   24.7   24.6
                                       Influenza A virus
        AF091307    Orthomyxoviridae   (A/swine/Wisconsin/1/61(H1N1))              1778   18.3   24.2   23.9
                                       Influenza A virus
        AF222026    Orthomyxoviridae   (A/Swine/Wisconsin/125/97(H1N1))            1773   22.0   20.3   25.3
                                       Influenza A virus
        AF222027    Orthomyxoviridae   (A/Swine/Wisconsin/136/97(H1N1))            1772   22.0   20.3   25.3
                                       Influenza A virus
        AF268126    Orthomyxoviridae   (A/Swine/Wisconsin/14094/99(H3N2))          1412   14.2   24.4   24.6
                                       Influenza A virus
        AF222028    Orthomyxoviridae   (A/Swine/Wisconsin/163/97(H1N1))            1747   23.8   20.6   25.1
                                       Influenza A virus
        AF222029    Orthomyxoviridae   (A/Swine/Wisconsin/164/97(H1N1))            1773   23.4   21.4   25.1
                                       Influenza A virus
        AF222030    Orthomyxoviridae   (A/Swine/Wisconsin/166/97(H1N1))            1773   23.4   20.9   24.9
                                       Influenza A virus
        AF222031    Orthomyxoviridae   (A/Swine/Wisconsin/168/97(H1N1))            1774   23.4   20.9   25.0
                                       Influenza A virus
        AF222032    Orthomyxoviridae   (A/Swine/Wisconsin/235/97(H1N1))            1774   23.1   21.4   25.1




                                                                Page 27
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


                                       Influenza A virus
        AF222033    Orthomyxoviridae (A/Swine/Wisconsin/238/97(H1N1))              1773   23.1   21.7   25.2
                                       Influenza A virus
        AF222034    Orthomyxoviridae   (A/Swine/Wisconsin/457/98(H1N1))            1773   23.4   20.9   25.0
                                       Influenza A virus
        AF222035    Orthomyxoviridae   (A/Swine/Wisconsin/458/98(H1N1))            1757   19.9   19.6   25.7
                                       Influenza A virus
        AF222036    Orthomyxoviridae   (A/Swine/Wisconsin/464/98(H1N1))            1737   20.1   19.3   25.6
                                       Influenza A virus (A/Switzerland/5389/95
        AF386774    Orthomyxoviridae   (H1N1))                                     1778   19.4   24.5   24.0
                                       Influenza A virus
        AY032978    Orthomyxoviridae   (A/Switzerland/7729/98(H3N2))               1762   13.3   25.0   24.2
                                       Influenza A virus (A/Switzerland/9243/99
        INA458276   Orthomyxoviridae   (H3N2))                                     1565   10.2   22.0   25.0
        INA311466   Orthomyxoviridae   Influenza A virus (A/Sydney/5/97(H3N2))     1653   15.1   23.6   24.5
        AF138711    Orthomyxoviridae   Influenza A virus (A/Taiwan/96/2191)        1758   19.1   24.2   24.9
                                       Influenza A virus (A/Teal/Hong
        AF250476    Orthomyxoviridae   Kong/W312/97(H6N1))                         2280   20.6   24.6   24.2
        ORFLAT77    Orthomyxoviridae   Influenza A virus (A/Texas/1/77(H3N2))      1565   10.5   24.0   24.9
        AY289927    Orthomyxoviridae   Influenza A virus (A/Texas/36/91(H1N1))     1778   20.5   22.8   23.5
        AB101673    Orthomyxoviridae   Influenza A virus (A/Texas/68(H2N2))        1410   19.9   22.7   26.7
        AF503464    Orthomyxoviridae Influenza A virus (A/Texas/7/2001(H1N2))      1410   26.2   21.6   25.0
                                       Influenza A virus
        INA457959   Orthomyxoviridae   (A/Toulouse/878/2001(H3N2))                 1403   21.7   26.0   23.4
                                       Influenza A virus
        AF533746    Orthomyxoviridae   (A/Tucuman/V425/98(H3N2))                   1466   22.9   22.2   24.9
                                       Influenza A virus
        AF533747    Orthomyxoviridae   (A/Tucuman/V694/98(H3N2))                   1466   22.9   22.5   24.9
                                       Influenza A virus (A/turkey/CA/D0208651-
        AY296083    Orthomyxoviridae   C/02(H5N2))                                 1708   18.7   27.5   25.2
                                       Influenza A virus (A/turkey/CA/D0208652-
        AY300945    Orthomyxoviridae   C/02(H5N2))                                 1410   23.8   30.5   25.7
                                       Influenza A virus
        AF156443    Orthomyxoviridae   (A/turkey/California/189/66(H9N2))          2257   15.1   27.0   25.6
                                       Influenza A virus
        AY300949    Orthomyxoviridae   (A/turkey/CO/13356/91(H7N3))                1332   18.4   22.9   24.5
                                       Influenza A virus (A/turkey/England/192-
        AF202245    Orthomyxoviridae   328/79(H7N3))                               1732   12.4   23.1   22.2
                                       Influenza A virus
        AF202238    Orthomyxoviridae   (A/turkey/England/63(H7N3))                 1659   11.2   23.2   21.9
                                       Influenza A virus
        AF202247    Orthomyxoviridae   (A/turkey/England/647/77(H7N7))             1732   10.4   24.5   22.3
                                       Influenza A virus
        INA507207   Orthomyxoviridae   (A/turkey/Germany/R04/99(H6N2))             1398   16.8   27.9   21.5
                                       Influenza A virus (A/turkey/Germany/R04-
        INA507203   Orthomyxoviridae   5/02(H6N2))                                 1398   18.6   29.0   21.5
                                       Influenza A virus
        INA507205   Orthomyxoviridae   (A/turkey/Germany/R14/02(H6N2))             1398   18.6   30.4   21.7
                                       Influenza A virus
        INA507204   Orthomyxoviridae   (A/turkey/Germany/R26/02(H6N2))             1398   19.0   31.1   21.9
                                       Influenza A virus
        INA507208   Orthomyxoviridae   (A/turkey/Germany/R26/99(H6N2))             1398   19.0   27.5   21.6
                                       Influenza A virus
        INA507209   Orthomyxoviridae   (A/turkey/Germany/R30/99(H6N1))             1401   19.6   27.5   21.1
                                       Influenza A virus
        INA507206   Orthomyxoviridae   (A/turkey/Germany/R43/98(H6N5))             1401   19.3   26.1   21.6
                                       Influenza A virus
        AF202235    Orthomyxoviridae   (A/turkey/Israel/Ramon/79(H7N2))            1732   14.1   23.1   23.4
                                       Influenza A virus
        INA489520   Orthomyxoviridae   (A/turkey/Italy/12598/99(H7N1))             1723   16.3   27.9   23.2
                                       Influenza A virus
        INA493213   Orthomyxoviridae   (A/turkey/Italy/13467/99(H7N1))             1723   16.3   27.6   23.2
                                       Influenza A virus
        INA493216   Orthomyxoviridae   (A/turkey/Italy/13468/99(H7N1))             1723   16.3   27.6   23.2
                                       Influenza A virus
        INA493217   Orthomyxoviridae   (A/turkey/Italy/335/00(H7N1))               1723   16.3   27.6   23.2
                                       Influenza A virus (A/turkey/Italy/3775/99
        INA493472   Orthomyxoviridae   (H7N1))                                     1711   15.5   28.3   22.7




                                                                 Page 28
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


                                       Influenza A virus (A/turkey/Italy/3889/99
        INA493466   Orthomyxoviridae (H7N1))                                       1711   15.5   28.3   22.9
                                       Influenza A virus (A/turkey/Italy/4073/99
        INA493467   Orthomyxoviridae   (H7N1))                                     1711   15.5   28.3   22.7
                                       Influenza A virus (A/turkey/Italy/4169/99
        INA493468   Orthomyxoviridae   (H7N1))                                     1711   16.1   28.1   22.7
                                       Influenza A virus (A/turkey/Italy/4602/99
        INA493470   Orthomyxoviridae   (H7N1))                                     1711   14.9   27.8   22.4
                                       Influenza A virus (A/turkey/Italy/4603/99
        INA493471   Orthomyxoviridae   (H7N1))                                     1711   15.8   28.1   22.6
                                       Influenza A virus
        AF091310    Orthomyxoviridae   (A/turkey/Minnesota/1661/81(H1N1))          1777   16.9   27.0   24.3
                                       Influenza A virus
        AF156387    Orthomyxoviridae (A/turkey/Minnesota/38391-6/95(H9N2))         1663   18.3   21.3   23.5
                                       Influenza A virus
        AY038014    Orthomyxoviridae   (A/Turkey/MO/24093/99(H1N2))                1701   24.1   20.6   25.0
                                       Influenza A virus
        AY240910    Orthomyxoviridae   (A/turkey/NC/11165/02(H7N2))                1670   15.6   28.1   22.8
                                       Influenza A virus
        AY254142    Orthomyxoviridae   (A/turkey/NC/11165/O2(H7N2))                1386   17.3   24.9   22.7
                                       Influenza A virus (A/turkey/New
        AF072386    Orthomyxoviridae   York/4450-5/94 (H7N2))                      1700   17.6   25.6   22.5
                                       Influenza A virus (A/turkey/NJ/9778-
        AY240911    Orthomyxoviridae   8/98(H7N2))                                 1655   17.2   27.8   22.9
                                       Influenza A virus (A/turkey/Northern
        AF202246    Orthomyxoviridae   Ireland/VF-1545 C5/98(H7N7))                1732   15.6   26.3   22.9
                                       Influenza A virus
        FLAHAH8N4   Orthomyxoviridae   (A/Turkey/Ontario/6118/68(H8N4))            1698   23.0   26.2   22.4
                                       Influenza A virus
        AY261521    Orthomyxoviridae   (A/turkey/Ontario/HR2/2000(H7N1))           1405   16.0   21.4   27.9
                                       Influenza A virus
        AF072397    Orthomyxoviridae   (A/Turkey/Pennsylvania/7975/97(H7N2))       1673   18.5   27.2   23.1
                                       Influenza A virus
        AY254149    Orthomyxoviridae   (A/Turkey/VA/158512/02(H7N2))               1385   17.3   24.9   22.7
                                       Influenza A virus
        AY240912    Orthomyxoviridae   (A/turkey/VA/55/02(H7N2))                   1670   15.6   28.1   23.3
                                       Influenza A virus
        AY240913    Orthomyxoviridae   (A/turkey/VA/66/02(H7N2))                   1670   15.9   28.1   23.2
                                       Influenza A virus
        AY240914    Orthomyxoviridae   (A/turkey/VA/67/02(H7N2))                   1668   15.3   28.2   23.6
                                       Influenza A virus
        FLAHAH9N2   Orthomyxoviridae   (A/turkey/Wisconsin/66(H9N2))               1683   16.9   25.3   22.3
        ORFLUD72    Orthomyxoviridae Influenza A virus (A/Udorn/307/72(H3N2))      1565   13.4   24.3   25.0
                                       Influenza A virus (A/unknown/NY/101250-
        AY296076    Orthomyxoviridae   18/01(H5N2))                                1735   21.0   27.4   25.6
                                       Influenza A virus (A/unknown/NY/118547-
        AY296078    Orthomyxoviridae   11/01(H5N2))                                1691   20.1   27.8   24.8
                                       Influenza A virus (A/unknown/NY/98899-
        AY300937    Orthomyxoviridae   6/01(H5N2))                                 1410   15.2   25.2   25.9
                                       Influenza A virus (A/unknown/NY/9899-
        AY296075    Orthomyxoviridae   6/01(H5N2))                                 1735   20.2   28.2   24.8
                                       Influenza A virus
        AF533730    Orthomyxoviridae   (A/Ushuaia/R127/98(H3N2))                   1466   22.9   22.2   24.9
                                       Influenza A virus
        AF533731    Orthomyxoviridae   (A/Ushuaia/R13/98(H3N2))                    1466   22.2   22.2   24.8
                                       Influenza A virus
        AF533733    Orthomyxoviridae   (A/Ushuaia/R254/98(H3N2))                   1466   22.9   21.5   25.1
                                       Influenza A virus
        AF533734    Orthomyxoviridae   (A/Ushuaia/R270/98(H3N2))                   1466   22.9   22.2   24.8
                                       Influenza A virus
        AF533735    Orthomyxoviridae   (A/Ushuaia/R272/98(H3N2))                   1466   22.9   22.2   24.8
                                       Influenza A virus
        AF533736    Orthomyxoviridae   (A/Ushuaia/R274/98(H3N2))                   1466   22.9   22.2   24.8
        ORFLAUS7    Orthomyxoviridae   Influenza A virus (A/USSR/90/77(H1N1))      1565   12.1   23.0   23.3
                                       Influenza A virus
        INA457960   Orthomyxoviridae   (A/Valladolid/4/2001(H3N2))                 1439   23.3   22.2   24.4
        AF072545    Orthomyxoviridae   Influenza A virus (A/Victoria/3/75)         1565   11.8   24.3   24.8
                                       Influenza A virus
        AF017270    Orthomyxoviridae   (A/Vienna/47/96M(H3N2))                     1762   14.8   23.3   24.1




                                                                 Page 29
Endoh et al. Supplement for Table 5                          ProbUniqueVirus


                                       Influenza A virus
        AF017272    Orthomyxoviridae (A/Vienna/47/96V(H3N2))                          1762   15.9   23.6   24.0
        AF494252    Orthomyxoviridae Influenza A virus (A/Weiss/43(H1N1))             1410   21.6   25.7   24.0
                                       Influenza A virus (A/Wild
        AF523454    Orthomyxoviridae Duck/Shantou/4808/01(H9N2))                      1740   10.6   26.4   26.5
                                       Influenza A virus (A/Wisconsin/10/98
        AF342823    Orthomyxoviridae   (H1N1))                                        2341   15.0   22.2   24.1
                                       Influenza A virus
        AF503463    Orthomyxoviridae   (A/Wisconsin/12/2001(H1N2))                    1410   26.2   21.3   25.3
        AY377569    Orthomyxoviridae Influenza A virus (A/Wuhan/359/95(H3N2))         1302   16.5   23.0   25.0
        INA344022   Orthomyxoviridae Influenza A virus (A/Wuhan/371/95(H1N1))         1666   18.6   21.6   24.0
                                       Influenza A virus (STRAIN
        S68489      Orthomyxoviridae   A/CHICKEN/SCOTLAND/59)                         1773   16.4   24.8   23.4
                                       Influenza A virus (strain
        FLAHAH3A    Orthomyxoviridae   A/equine/Argentina/1/93)                       1762   17.0   22.4   23.7
                                       Influenza A virus (strain
        FLAHAH3D    Orthomyxoviridae   A/equine/Florida/1/93)                         1762   16.5   23.8   24.2
                                       Influenza A virus (strain
        FLAHAH3C    Orthomyxoviridae   A/equine/Kentucky/1/90)                        1762   16.7   23.8   24.5
                                       Influenza A virus (strain
        FLAHAH3F    Orthomyxoviridae   A/equine/Kentucky/1/91)                        1762   16.7   23.0   24.2
                                       Influenza A virus (strain
        FLAHAH3E    Orthomyxoviridae   A/equine/Kentucky/1/92)                        1762   17.9   22.1   24.6
                                       Influenza A virus (strain
        FLAHAH3B    Orthomyxoviridae   A/equine/Kentucky/1/94)                        1762   16.7   23.8   24.6
                                       Influenza A virus (STRAIN A/FORT
        IAPB247     Orthomyxoviridae   MONMOUTH/1/47)                                 2341   16.0   26.3   25.5
                                       Influenza A virus (STRAIN A/FOWL
        IAV43991    Orthomyxoviridae   PLAGUE VIRUS/ROSTOCK/34)                       2217   15.6   25.0   24.5
                                       Influenza A virus (STRAIN
        IAV43994    Orthomyxoviridae   A/MALLARD/NEW YORK/6750/78)                    2151   10.2   28.1   24.7
        FLANPMEM9   Orthomyxoviridae   Influenza A virus (strain A/memphis/4/73)      1565   12.8   23.3   24.6
                                       Influenza A virus (strain
        IAU72666    Orthomyxoviridae   A/swine/England/117316/86)                     1778   19.7   21.4   23.8
                                       Influenza A virus (strain
        IAU72667    Orthomyxoviridae   A/swine/England/195852/92)                     1777   18.3   28.7   24.0
                                       Influenza A virus (strain
        IAU72668    Orthomyxoviridae   A/swine/England/283902/93)                     1778   20.5   22.5   24.2
                                       Influenza A virus (strain A/swine/Schleswig-
        IAU72669    Orthomyxoviridae   Holstein/1/93)                                 1778   17.2   27.8   24.5
                                       Influenza A virus
        INA306860   Orthomyxoviridae   (swine/Finistere/127/99(H3N2))                 2268   13.9   21.8   23.5
        AB036782    Orthomyxoviridae   Influenza A virus (X-31(H3N2))                 2341   17.8   26.0   25.1
        U71135      Orthomyxoviridae   Influenza A virus H3N2                         2280   16.4   29.5   24.1
        AF102681    Orthomyxoviridae   Influenza A virus isolate hk48597              1656   17.2   21.7   23.7
        AF102671    Orthomyxoviridae   Influenza A virus isolate hk48697              1656   18.1   20.5   24.0
        AF102672    Orthomyxoviridae   Influenza A virus isolate hk48897              1656   18.1   20.2   24.2
        AF102677    Orthomyxoviridae   Influenza A virus isolate hk49197              1656   16.3   20.2   23.6
        AF102679    Orthomyxoviridae   Influenza A virus isolate hk50397              1656   16.9   21.1   24.0
        AF102675    Orthomyxoviridae   Influenza A virus isolate hk50797              1656   18.1   21.1   23.9
        AF102682    Orthomyxoviridae   Influenza A virus isolate hk51497              1656   19.0   22.3   23.7
        AF102673    Orthomyxoviridae   Influenza A virus isolate hk51697              1656   18.7   20.5   24.1
        AF102680    Orthomyxoviridae   Influenza A virus isolate hk53297              1656   17.8   20.8   24.1
        AF102674    Orthomyxoviridae   Influenza A virus isolate hk53897              1656   18.7   20.5   24.2
        AF102678    Orthomyxoviridae   Influenza A virus isolate hk54297              1656   16.3   19.6   23.7
        AF102676    Orthomyxoviridae   Influenza A virus isolate hk9798               1656   18.7   20.8   24.1
                                       Influenza A virus
                                       PX14(A/USSR/90/77(H1N1)xA/PintailDuc
        AF290441    Orthomyxoviridae   k/Primorie/695/76(H2N3))                       1717   14.6   28.0   23.9
                                       Influenza A virus PX14-
                                       XIII(A/USSR/90/77(H1N1)xA/PintailDuck/
        AF290442    Orthomyxoviridae   Primorie/695/76(H2N3))                         1717   14.6   28.2   23.7
                                       Influenza A virus
                                       PX8(A/USSR/90/77(H1N1)xA/PintailDuck
        AF290439    Orthomyxoviridae   /Primorie/695/76(H2N3))                        1717   15.4   28.2   23.8




                                                                   Page 30
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


                                       Influenza A virus PX8-
                                       XIII(A/USSR/90/77(H1N1)xA/PintailDuck/
        AF290440    Orthomyxoviridae   Primorie/695/76(H2N3))                    1717   14.6   28.2   23.8
                                       Influenza A virus
                                       RCB1(A/USSR/90/77(H1N1)xA/Duck/Cze
        AF290437    Orthomyxoviridae   choslovakia/56(H4N6))                     1714   18.7   24.2   25.1
                                       Influenza A
        AY036880    Orthomyxoviridae   virus(A/Chicken/Guangxi/KMI/99(H9N2))     1683   25.3   23.2   23.9
        ORFLBPB2    Orthomyxoviridae   Influenza B virus                         2396   17.9   27.3   20.9
        AF101973    Orthomyxoviridae   Influenza B virus (B/Aichi/5/88)          2313   21.0   26.4   20.3
        AY139059    Orthomyxoviridae   Influenza B virus (B/Alaska/16/2000)      1446   18.0   27.7   23.0
        AY139071    Orthomyxoviridae   Influenza B virus (B/Argentina/69/2001)   1465   16.0   25.6   22.7
        AY139056    Orthomyxoviridae   Influenza B virus (B/Bangkok/34/99)       1408   14.6   25.2   22.6
        AY139055    Orthomyxoviridae   Influenza B virus (B/Bangkok/54/99)       1408   15.6   24.9   22.7
        AF101974    Orthomyxoviridae   Influenza B virus (B/Beijing/184/93)      2313   18.4   27.2   20.5
        AF101975    Orthomyxoviridae   Influenza B virus (B/Beijing/243/97)      2313   20.5   26.8   20.4
        ORHA1HA2    Orthomyxoviridae   Influenza B virus (B/Bonn/43)             1822   15.9   22.5   22.6
        AY139070    Orthomyxoviridae   Influenza B virus (B/Brazil/952/2001)     1457   16.8   24.0   22.8
        AY139065    Orthomyxoviridae   Influenza B virus (B/Canada/464/2001)     1462   17.1   24.6   22.4
        AF101976    Orthomyxoviridae   Influenza B virus (B/Chiba/447/98)        2313   21.6   27.0   20.5
        AF101978    Orthomyxoviridae   Influenza B virus (B/Guangdong/05/94)     2313   21.6   26.2   20.0
        AF101977    Orthomyxoviridae   Influenza B virus (B/Guangdong/08/93)     2313   21.4   27.2   20.9
        AY139079    Orthomyxoviridae   Influenza B virus (B/Guangdong/5/94)      1511   14.6   24.8   22.4
        AY139052    Orthomyxoviridae   Influenza B virus (B/Guangzhou/7/97)      1408   15.3   24.5   22.1
        AF170572    Orthomyxoviridae   Influenza B virus (B/Harbin/07/94)        2327   18.3   27.9   20.8
        AY139067    Orthomyxoviridae   Influenza B virus (B/Hawaii/10/2001)      1472   16.3   25.1   22.6
        AY139069    Orthomyxoviridae   Influenza B virus (B/Hawaii/36/2001)      1453   16.5   25.1   22.4
        AF101980    Orthomyxoviridae   Influenza B virus (B/Henan/22/97)         2313   21.2   27.0   20.4
        AF387497    Orthomyxoviridae   Influenza B virus (B/Hong Kong/110/99)    1882   16.2   26.0   22.2
                                       Influenza B virus (B/Hong
        AY139074    Orthomyxoviridae   Kong/1351/2002)                           1511   17.2   27.1   23.6
        AF387499    Orthomyxoviridae   Influenza B virus (B/Hong Kong/147/99)    1882   16.2   25.8   22.3
        AF387501    Orthomyxoviridae   Influenza B virus (B/Hong Kong/156/99)    1882   16.7   26.8   22.4
        AF387503    Orthomyxoviridae   Influenza B virus (B/Hong Kong/157/99)    1882   16.7   26.8   22.4
        AY139063    Orthomyxoviridae   Influenza B virus (B/Hong Kong/22/2001)   1470   16.0   25.2   22.3
        AY139064    Orthomyxoviridae   Influenza B virus (B/Hong Kong/28/2001)   1465   16.4   24.9   22.1
        AY191502    Orthomyxoviridae Influenza B virus (B/Hong Kong/330/2001)    1555   17.0   25.1   22.4
        AY191498    Orthomyxoviridae Influenza B virus (B/Hong Kong/548/2000)    1882   16.7   27.1   22.5
        AY139057    Orthomyxoviridae Influenza B virus (B/Hong Kong/557/2000)    1408   17.0   27.3   22.4
        AY139062    Orthomyxoviridae Influenza B virus (B/Hong Kong/6/2001)      1464   16.1   25.3   21.9
        AY139050    Orthomyxoviridae Influenza B virus (B/Hong Kong/70/96)       1408   17.4   24.1   22.9
        AF101981    Orthomyxoviridae Influenza B virus (B/Ibaraki/2/85)          2313   21.0   26.4   20.3
        FLBNB       Orthomyxoviridae Influenza B virus (B/Kanagawa/73)           1408   16.8   24.6   23.1
        AB036875    Orthomyxoviridae Influenza B virus (B/Kouchi/193/99)         1683   10.4   22.6   22.3
        AF101982    Orthomyxoviridae Influenza B virus (B/Lee/40)                2313   17.1   27.5   23.0
        AY139073    Orthomyxoviridae Influenza B virus (B/Malaysia/83077/2001)   1483   15.8   23.6   22.5
        AY139076    Orthomyxoviridae Influenza B virus (B/Maryland/1/2002)       1446   16.9   26.3   23.7
        AF129893    Orthomyxoviridae Influenza B virus (B/Memphis/10/97)         1775   16.3   25.9   22.3
        AY260943    Orthomyxoviridae Influenza B virus (B/Memphis/12/97)         2369   19.8   28.3   20.3
        AY260950    Orthomyxoviridae Influenza B virus (B/Memphis/12/97-MA)      2360   19.9   28.4   20.3
        AF129921    Orthomyxoviridae Influenza B virus (B/Memphis/20/96)         1421   15.1   25.7   23.9
        AF129915    Orthomyxoviridae Influenza B virus (B/Memphis/3/93)          1400   14.6   25.0   23.0
        AF101983    Orthomyxoviridae Influenza B virus (B/Mie/1/93)              2313   17.9   27.2   20.5
        AB036876    Orthomyxoviridae Influenza B virus (B/Nagoya/20/99)          1683   11.3   21.1   22.1
        AY139075    Orthomyxoviridae Influenza B virus (B/New York/1/2002)       1484   17.2   27.0   23.8
        AF101984    Orthomyxoviridae Influenza B virus (B/Norway/1/84)           2313   19.2   26.4   21.2
        AY139072    Orthomyxoviridae Influenza B virus (B/Oman/16296/2001)       1476   15.9   25.1   22.3
        AY139054    Orthomyxoviridae Influenza B virus (B/Osaka/547/97)          1408   15.6   24.5   22.2
        AF129908    Orthomyxoviridae Influenza B virus (B/Panama/45/90)          1405   17.1   25.3   23.3
        AB036874    Orthomyxoviridae Influenza B virus (B/Saga/S172/99)          1683    9.8   22.9   22.2




                                                                Page 31
Endoh et al. Supplement for Table 5                          ProbUniqueVirus


        AF484967    Orthomyxoviridae Influenza B virus (B/Shangdong/7/97)        2269   21.6   25.6   20.8
        AF101985    Orthomyxoviridae Influenza B virus (B/Shiga/51/98)           2313   21.2   26.6   20.4
        AF101986    Orthomyxoviridae Influenza B virus (B/Shiga/T30/98)          2313   18.4   28.1   20.8
        AY139051    Orthomyxoviridae Influenza B virus (B/Sichuan/281/96)        1408   16.3   23.8   22.5
        AY139068    Orthomyxoviridae Influenza B virus (B/Sichuan/317/2001)      1446   16.6   26.3   22.3
        AY139080    Orthomyxoviridae Influenza B virus (B/Sichuan/379/99)        1446   18.0   25.9   22.7
        AF101987    Orthomyxoviridae Influenza B virus (B/Singapore/222/79)      2313   20.1   26.2   20.9
        AF387505    Orthomyxoviridae Influenza B virus (B/Switzerland/4291/97)   1882   15.7   26.3   22.2
        AY139053    Orthomyxoviridae Influenza B virus (B/Taiwan/217/97)         1408   15.6   24.9   22.8
        AY139058    Orthomyxoviridae Influenza B virus (B/Texas/1/2000)          1408   17.8   28.1   22.9
        IBIBN       Orthomyxoviridae Influenza B virus (B/Texas/37/88)           1753   10.3   24.0   22.2
        ORHA12BU    Orthomyxoviridae Influenza B virus (B/USSR/100/83)           1825   15.1   27.7   22.8
        AF101988    Orthomyxoviridae Influenza B virus (B/Victoria/2/87)         2313   20.3   26.4   20.2
        AF387495    Orthomyxoviridae Influenza B virus (B/Vienna/1/99)           1882   16.7   26.6   22.4
        AY139061    Orthomyxoviridae Influenza B virus (B/Wuhan/2/2001)          1472   16.0   25.8   22.7
        AY139060    Orthomyxoviridae Influenza B virus (B/Wuhan/356/2000)        1446   16.6   26.3   22.3
        AF101989    Orthomyxoviridae Influenza B virus (B/Yamagata/16/88)        2313   17.7   27.7   20.7
        AF101990    Orthomyxoviridae Influenza B virus (B/Yamanashi/166/98)      2313   20.3   27.9   20.4
                                        Influenza B virus (STRAIN B/ANN
        INBNP       Orthomyxoviridae ARBOR/1/86)                                 1811   12.1   26.0   23.0
        ORFLCPB2    Orthomyxoviridae Influenza C virus                           2365   16.3   23.9   22.5
        AF170576    Orthomyxoviridae Influenza C virus (C/Johannesburg/1/66)     2330   16.1   23.6   22.1
        AB086658    Orthomyxoviridae Influenza C virus (C/Miyagi/1/90)           1926   12.7   23.1   25.3
        AB064407    Orthomyxoviridae Influenza C virus (C/Miyagi/1/93)           1923   17.4   26.8   25.7
        AB064412    Orthomyxoviridae Influenza C virus (C/Miyagi/1/94)           1923   16.4   26.3   25.8
        AB086665    Orthomyxoviridae Influenza C virus (C/Miyagi/1/97)           1926   14.8   26.0   25.0
        AB086668    Orthomyxoviridae Influenza C virus (C/Miyagi/1/99)           1926   14.8   25.4   25.1
        AB064413    Orthomyxoviridae Influenza C virus (C/Miyagi/2/94)           1923   16.6   26.3   25.9
        AB086662    Orthomyxoviridae Influenza C virus (C/Miyagi/2/96)           1926   14.8   25.2   25.1
        AB086666    Orthomyxoviridae Influenza C virus (C/Miyagi/2/98)           1926   15.1   24.9   25.3
        AB064408    Orthomyxoviridae Influenza C virus (C/Miyagi/3/93)           1923   16.6   26.0   26.0
        AB064414    Orthomyxoviridae Influenza C virus (C/Miyagi/3/94)           1923   16.4   26.3   25.8
        AB086669    Orthomyxoviridae Influenza C virus (C/Miyagi/3/99)           1926   14.8   25.4   25.1
        AB064409    Orthomyxoviridae Influenza C virus (C/Miyagi/4/93)           1923   16.6   25.7   25.9
        AB064404    Orthomyxoviridae Influenza C virus (C/Miyagi/4/96)           1923   16.9   26.8   25.7
        AB086667    Orthomyxoviridae Influenza C virus (C/Miyagi/4/98)           1926   14.8   25.2   24.9
        AB086659    Orthomyxoviridae Influenza C virus (C/Miyagi/5/91)           1926   12.7   23.4   25.3
        AB086661    Orthomyxoviridae Influenza C virus (C/Miyagi/5/93)           1926   11.9   23.4   24.8
        AB064410    Orthomyxoviridae Influenza C virus (C/Miyagi/6/93)           1923   17.2   26.8   25.7
        AB086663    Orthomyxoviridae Influenza C virus (C/Miyagi/6/96)           1926   14.5   25.2   25.0
        AB086660    Orthomyxoviridae Influenza C virus (C/Miyagi/7/91)           1926   13.2   24.4   25.3
        AB064411    Orthomyxoviridae Influenza C virus (C/Miyagi/7/93)           1923   17.2   26.8   25.7
        AB064405    Orthomyxoviridae Influenza C virus (C/Miyagi/7/96)           1923   16.9   26.5   25.6
        AB064406    Orthomyxoviridae Influenza C virus (C/Miyagi/8/96)           1923   15.6   25.2   25.6
        AB086664    Orthomyxoviridae Influenza C virus (C/Miyagi/9/96)           1926   13.8   26.2   25.5
        FLCHEG      Orthomyxoviridae Influenza C virus (C/Nara/2/85)             1987   13.3   25.7   25.2
        AB086656    Orthomyxoviridae Influenza C virus (C/Shizuoka/79)           1926   13.5   24.4   25.0
        AB086657    Orthomyxoviridae Influenza C virus (C/Yamagata/1/86)         1926   14.0   23.9   25.6
        D49361      Orthomyxoviridae Influenza C virus (C/Yamagata/10/89)        1983   13.4   25.5   25.1
        AB064403    Orthomyxoviridae Influenza C virus (C/Yamagata/13/98)        1926   14.8   25.4   25.0
        AB064401    Orthomyxoviridae Influenza C virus (C/Yamagata/2/98)         1926   14.8   25.2   24.9
        AB064400    Orthomyxoviridae Influenza C virus (C/Yamagata/20/96)        1926   14.3   25.2   24.9
        AB064397    Orthomyxoviridae Influenza C virus (C/Yamagata/3/96)         1926   14.8   25.2   25.2
        ICD433      Orthomyxoviridae Influenza C virus (C/Yamagata/5/92)         1961   16.8   26.8   26.1
        AB064402    Orthomyxoviridae Influenza C virus (C/Yamagata/6/98)         1926   14.8   25.2   24.9
        AB064398    Orthomyxoviridae Influenza C virus (C/Yamagata/8/96)         1926   14.8   25.2   25.0
        AB064399    Orthomyxoviridae Influenza C virus (C/Yamagata/9/96)         1926   14.5   25.2   25.0
                                        Influenza C virus (STRAIN
        INFVBP2     Orthomyxoviridae C/BERLIN/1/85)                              2340   17.3   23.5   22.2
        IV08904     Orthomyxoviridae Influenza virus                             1746   19.9   21.0   24.6
                                        Influenzavirus A
        AF501235    Orthomyxoviridae (A/duck/Shanghai/1/2000)                    1729   18.5   22.3   24.2




                                                                    Page 32
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


        TVI17873    Orthomyxoviridae Thogoto virus                                 2375   21.9   21.3   22.9
        PAPABPV1    Papillomaviridae Bovine papillomavirus                         7945   16.3   26.2   23.4
        PA1P        Papillomaviridae Bovine papillomavirus type 1                  4807   18.1   25.9   22.7
        PAPPPB2C    Papillomaviridae Bovine papillomavirus type 2                  7937   16.3   25.7   23.7
        AF486184    Papillomaviridae Bovine papillomavirus type 3                  7276   20.5   24.9   24.1
        PABPV4XX    Papillomaviridae Bovine papillomavirus type 4                  7265   17.5   27.5   25.0
        AF457465    Papillomaviridae Bovine papillomavirus type 5                  7841   17.7   26.5   22.5
        PAPPPHCG    Papillomaviridae Canine oral papillomavirus                    8607   18.2   26.6   23.2
        AF020905    Papillomaviridae Common chimpanzee papillomavirus 1            7889   29.5   25.2   22.8
        PSY404003   Papillomaviridae Cottontail rabbit papillomavirus              7868   19.3   26.7   24.3
        PAPPPDCG    Papillomaviridae Deer papillomavirus                           8374   14.9   24.9   24.7
        AF394740    Papillomaviridae Equinus papillomavirus                        7613   15.0   23.8   23.6
        AF498323    Papillomaviridae Equus caballus papillomavirus type 1          7610   15.1   23.7   23.6
        PAPPPECG    Papillomaviridae European elk papillomavirus                   8095   17.5   23.1   23.9
        AF377865    Papillomaviridae Feline papillomavirus                         8300   18.0   24.5   23.6
        AF480454    Papillomaviridae Felis domesticus papillomavirus type 1        8300   18.0   24.5   23.6
        AY057109    Papillomaviridae Fringilla coelebs papillomavirus              7729   20.5   23.2   23.9
        PAPPPCCG    Papillomaviridae Hamster papovavirus                           5366   19.0   24.0   23.9
                                        Homo sapiens (human)Human
        HSH2        Papillomaviridae    papillomavirus type 5b                     8852   20.3   23.9   24.3
        AF131950    Papillomaviridae    Human papillomavirus candHPV85             7812   33.0   24.4   21.7
        HPU85660    Papillomaviridae    Human papillomavirus RTRX7                 7731   24.3   26.4   24.4
        HPV10       Papillomaviridae    Human papillomavirus type 10               7919   25.2   22.5   23.2
        PAPPPH11    Papillomaviridae    Human papillomavirus type 11               7931   26.6   24.2   22.3
        HPV12       Papillomaviridae    Human papillomavirus type 12               7673   22.0   25.9   24.0
        HPVT13DNA   Papillomaviridae    Human papillomavirus type 13               7880   28.0   26.6   22.6
        HPV14D      Papillomaviridae    Human papillomavirus type 14D              7439   25.7   26.6   24.1
        HPV15       Papillomaviridae    Human papillomavirus type 15               7412   24.9   25.6   23.6
        AF472508    Papillomaviridae    Human papillomavirus type 16               7908   33.7   25.4   22.0
                                        Human papillomavirus type 16Homo sapiens
        HPAF1600    Papillomaviridae    (human)                                    4550   34.3   26.2   21.1
        HPV17       Papillomaviridae    Human papillomavirus type 17               7427   23.8   26.1   23.4
        PAPHPV18    Papillomaviridae    Human papillomavirus type 18               7857   30.5   24.0   22.4
        HPV19       Papillomaviridae    Human papillomavirus type 19               7685   26.9   28.0   23.3
        PAPAPI      Papillomaviridae    Human papillomavirus type 1a               7815   21.4   25.5   22.9
        HP31778     Papillomaviridae    Human papillomavirus type 20               7757   22.9   27.8   24.1
        HP31779     Papillomaviridae    Human papillomavirus type 21               7779   28.2   27.0   23.7
        HP31780     Papillomaviridae    Human papillomavirus type 22               7368   26.6   26.2   23.9
        HP31781     Papillomaviridae    Human papillomavirus type 23               7324   26.1   24.7   23.6
        HP31782     Papillomaviridae    Human papillomavirus type 24               7452   22.0   25.1   23.5
        HPV25       Papillomaviridae    Human papillomavirus type 25               7713   22.6   23.9   24.1
        HPV26       Papillomaviridae    Human papillomavirus type 26               7855   31.4   24.6   22.2
        HPV27       Papillomaviridae    Human papillomavirus type 27               7823   18.0   23.1   22.7
        HP31783     Papillomaviridae    Human papillomavirus type 28               7959   19.5   22.9   22.7
        HP31784     Papillomaviridae    Human papillomavirus type 29               7916   23.0   23.8   22.9
        PAHPV2A     Papillomaviridae    Human papillomavirus type 2a               7860   17.6   23.0   22.8
        HPV3        Papillomaviridae    Human papillomavirus type 3                7820   20.4   23.0   23.1
        HPV30       Papillomaviridae    Human papillomavirus type 30               7852   25.9   25.0   22.3
        PAPPPH31    Papillomaviridae    Human papillomavirus type 31               7912   32.2   24.2   23.8
        HPV32       Papillomaviridae    Human papillomavirus type 32               7961   27.2   24.1   23.2
        PAPPPH33    Papillomaviridae    Human papillomavirus type 33               7909   31.0   25.9   22.4
        HPV34       Papillomaviridae    Human papillomavirus type 34               7723   30.9   24.9   23.1
        PAPPPH35C   Papillomaviridae    Human papillomavirus type 35               7851   33.6   25.0   22.4
        HPV35H      Papillomaviridae    Human papillomavirus type 35H              7879   32.2   25.3   22.3
        HP31785     Papillomaviridae    Human papillomavirus type 36               7722   23.5   26.4   24.2
        HP31786     Papillomaviridae    Human papillomavirus type 37               7421   24.7   25.4   24.2
        HP31787     Papillomaviridae    Human papillomavirus type 38               7400   23.8   26.5   24.0
        PAPPPVT3    Papillomaviridae    Human papillomavirus type 39               7833   27.6   22.5   22.9
        PAPPH4      Papillomaviridae    Human papillomavirus type 4                7353   23.5   26.5   24.1
        HPV40       Papillomaviridae    Human papillomavirus type 40               7909   26.1   25.0   23.1
        PAP41CG     Papillomaviridae    Human papillomavirus type 41               7614   20.1   21.5   24.8
        PAPPPHPAP   Papillomaviridae    Human papillomavirus type 42               7917   26.7   24.2   22.4




                                                                 Page 33
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


        HP31788     Papillomaviridae   Human papillomavirus type 44                7833   30.3   23.4   22.2
        HPV45       Papillomaviridae   Human papillomavirus type 45                7858   30.0   25.7   22.6
        PAPPPH47    Papillomaviridae   Human papillomavirus type 47                7726   22.2   24.6   24.1
        HP31789     Papillomaviridae   Human papillomavirus type 48                7100   26.1   28.0   23.6
        HPV49       Papillomaviridae   Human papillomavirus type 49                7560   26.7   24.2   23.4
        PAPPPH5C    Papillomaviridae   Human papillomavirus type 5                 7746   23.4   26.2   24.4
        HP31790     Papillomaviridae   Human papillomavirus type 50                7184   24.7   26.1   24.4
        PAPPPHDN    Papillomaviridae   Human papillomavirus type 51                7808   28.8   24.7   22.7
        HPV52       Papillomaviridae   Human papillomavirus type 52                7942   29.1   25.4   21.5
        HPV53       Papillomaviridae   Human papillomavirus type 53                7856   27.4   26.0   22.6
        HP37488     Papillomaviridae   Human papillomavirus type 54                7759   28.7   25.3   22.6
        HP31791     Papillomaviridae   Human papillomavirus type 55                7822   28.7   24.0   22.3
        HPV56       Papillomaviridae   Human papillomavirus type 56                7844   32.8   26.5   22.2
        PAHPV57     Papillomaviridae   Human papillomavirus type 57                7861   19.7   22.6   23.2
        HPU37537    Papillomaviridae   Human papillomavirus type 57b               7868   19.8   22.2   23.0
        PAPPPH58    Papillomaviridae   Human papillomavirus type 58                7824   28.8   23.5   22.1
        HPV59VG     Papillomaviridae   Human papillomavirus type 59                7896   30.1   27.3   21.6
        PAPPPH5BC   Papillomaviridae   Human papillomavirus type 5b                7779   22.5   25.6   24.3
        AF092932    Papillomaviridae   Human papillomavirus type 6                 8012   25.8   24.5   22.3
        HP31792     Papillomaviridae   Human papillomavirus type 60                7313   26.0   28.9   24.2
        HP31793     Papillomaviridae   Human papillomavirus type 61                7989   20.3   24.3   22.4
        PAPPH63     Papillomaviridae   Human papillomavirus type 63                7348   26.3   25.4   23.9
        PAPPH65     Papillomaviridae   Human papillomavirus type 65                7308   21.8   27.1   23.6
        HP31794     Papillomaviridae   Human papillomavirus type 66                7824   30.1   25.4   22.0
        D21208      Papillomaviridae   Human papillomavirus type 67                7801   30.6   25.3   23.2
                                       Human papillomavirus type 68Homo sapiens
        HSFUSION    Papillomaviridae   (human)                                     4618    7.7   18.7   24.8
        AB027020    Papillomaviridae   Human papillomavirus type 69                7700   27.2   23.9   21.8
        PAPPPHE61   Papillomaviridae   Human papillomavirus type 6a                8010   26.5   24.7   22.5
        PAPA6B      Papillomaviridae   Human papillomavirus type 6b                7902   26.0   24.3   22.5
        HPV7        Papillomaviridae   Human papillomavirus type 7                 8027   27.8   26.8   22.3
        HP21941     Papillomaviridae   Human papillomavirus type 70                7905   30.7   23.9   22.1
        AB040456    Papillomaviridae   Human papillomavirus type 71                8017   25.1   24.1   22.6
        HPVT72ELG   Papillomaviridae   Human papillomavirus type 72                7988   24.7   23.9   22.2
        HPVT73ELG   Papillomaviridae   Human papillomavirus type 73                7700   30.8   24.9   22.8
        AF436130    Papillomaviridae   Human papillomavirus type 74                7887   26.8   24.1   22.2
        HPVY15173   Papillomaviridae   Human papillomavirus type 75                7537   25.3   24.7   24.2
        HPVY15174   Papillomaviridae   Human papillomavirus type 76                7549   23.2   24.5   23.1
        HPVY15175   Papillomaviridae   Human papillomavirus type 77                7887   19.9   21.9   22.6
        PAPPPH8C    Papillomaviridae   Human papillomavirus type 8                 7654   23.8   25.0   23.7
        HPVY15176   Papillomaviridae   Human papillomavirus type 80                7427   24.8   24.9   23.9
        AF293961    Papillomaviridae   Human papillomavirus type 82                7904   29.0   25.7   21.5
        AF151983    Papillomaviridae   Human papillomavirus type 83                8104   27.3   23.8   22.4
        AF293960    Papillomaviridae   Human papillomavirus type 84                7948   22.9   23.2   21.7
        AF349909    Papillomaviridae   Human papillomavirus type 86                7983   24.3   23.2   22.3
        HPA400628   Papillomaviridae   Human papillomavirus type 87                7998   23.6   23.3   21.4
        AF436128    Papillomaviridae   Human papillomavirus type 89                8078   25.6   23.6   22.8
        HPV9        Papillomaviridae   Human papillomavirus type 9                 7434   27.9   27.0   23.5
        AY057438    Papillomaviridae   Human papillomavirus type 90                8033   23.3   23.2   21.5
        AF419318    Papillomaviridae   Human papillomavirus type 91                7966   26.2   24.8   22.8
        AF531420    Papillomaviridae   Human papillomavirus type 92                7461   24.4   25.5   24.7
        AY382778    Papillomaviridae   Human papillomavirus type 93                7450   21.3   28.5   23.2
        AY382779    Papillomaviridae   Human papillomavirus type 96                7539   20.6   22.7   24.2
                                       Human papillomavirusHomo sapiens
        HSHPVME18   Papillomaviridae   (human)                                     6042   31.7   22.3   22.9
        PAPPPMCG    Papillomaviridae   Monkey B-lymphotropic papovavirus           5089   18.3   24.8   22.9
        PAPU01834   Papillomaviridae   Multimammate rat papillomavirus             7687   18.4   21.3   24.0
        OPU83594    Papillomaviridae   Ovine papillomavirus 1                      7761   21.2   26.2   23.9
        OPU83595    Papillomaviridae   Ovine papillomavirus 2                      7758   19.3   26.8   23.6
        PSP238373   Papillomaviridae   Phocoena spinipinnis papillomavirus         7879   17.6   22.8   24.2
        AF502599    Papillomaviridae   Psittacus erithacus papillomavirus          7304   25.3   21.7   23.4
        AF420235    Papillomaviridae   Psittacus erithacus timneh papillomavirus   7304   25.3   21.7   23.4




                                                                 Page 34
Endoh et al. Supplement for Table 5                         ProbUniqueVirus


        PCPVT1DNA   Papillomaviridae   Pygmy chimpanzee papillomavirus type 1    7902   30.9   24.9   22.7
        AF227240    Papillomaviridae   Rabbit oral papillomavirus                7565   19.5   24.9   24.5
        AF443292    Papillomaviridae   Reindeer papillomavirus                   8090   17.6   25.3   25.0
        PAPRPLCG    Papillomaviridae   Rhesus monkey papillomavirus              8028   16.2   24.8   22.5
        AF063497    Parvoviridae       Adeno-associated virus 1                  4718    7.5   24.4   25.1
        AF043303    Parvoviridae       Adeno-associated virus 2                  4679    8.9   21.1   24.0
        AVU48704    Parvoviridae       Adeno-associated virus 3                  4726   11.6   22.9   25.1
        AF028705    Parvoviridae       Adeno-associated virus 3B                 4722   12.1   23.1   25.0
        U89790      Parvoviridae       Adeno-associated virus 4                  4767    6.3   22.6   23.7
        AF085716    Parvoviridae       Adeno-associated virus 5                  4642    9.2   19.5   23.6
        AF028704    Parvoviridae       Adeno-associated virus 6                  4683    8.6   24.8   24.8
        AF513851    Parvoviridae       Adeno-associated virus 7                  4721    9.2   23.2   24.8
        AF513852    Parvoviridae       Adeno-associated virus 8                  4393    7.1   23.3   24.3
        AY095351    Parvoviridae       Aedes albopictus C6/36 cell densovirus    4094   26.6   21.9   22.3
        AAPARV      Parvoviridae       Aedes albopictus densovirus               4176   26.8   25.5   22.7
        ADNVDNA     Parvoviridae       Aedes densovirus                          3978   30.4   24.8   23.2
        PARMDPCG    Parvoviridae       Aleutian mink disease virus               4801   30.3   24.5   24.8
        AF317513    Parvoviridae       Autonomous rat parvovirus RV-Y            3530   13.3   26.2   24.7
                                       Avian adeno-associated virus ATCC VR-
        AY186198    Parvoviridae       865                                       4694   12.4   22.6   23.3
        AY386330    Parvoviridae       B19 virus                                 5596   25.7   25.3   24.0
        BD22967     Parvoviridae       Barbarie duck parvovirus                  5132   16.4   22.6   23.6
        AY189948    Parvoviridae       Blattella germanica densovirus            5335   25.5   22.9   24.7
        PARDNVOR    Parvoviridae       Bombyx mori densovirus                    4277   24.0   24.9   22.1
        AY033435    Parvoviridae       Bombyx mori densovirus 1                  5076   25.2   25.1   22.7
        AB042597    Parvoviridae       Bombyx mori densovirus 5                  5078   24.7   24.7   22.7
        PARPVBCG    Parvoviridae       Bovine parvovirus                         5517   15.1   21.7   24.0
        AF406966    Parvoviridae       Bovine parvovirus 2                       5610   21.8   20.9   21.9
        AF406967    Parvoviridae       Bovine parvovirus 3                       5276   15.8   22.9   22.6
        PARPVC01    Parvoviridae       Canine parvovirus                         5323   28.3   28.1   23.3
        AF375296    Parvoviridae       Casphalia extranea densovirus             5002   27.0   28.9   23.1
        CPU86868    Parvoviridae       Chipmunk parvovirus                       5097   16.6   21.6   22.1
        AF036333    Parvoviridae       Diatraea saccharalis densovirus           5941   32.6   27.3   24.6
        AY064476    Parvoviridae       Erythrovirus A6                           4844   24.3   27.5   22.6
        PARPVFPV    Parvoviridae       Feline panleukopenia virus                5124   26.7   27.7   23.2
        PARDNVCAP   Parvoviridae       Galleria mellonella densovirus            6039   29.8   27.7   23.9
        GP25749     Parvoviridae       Goose parvovirus                          5106   14.3   20.4   23.5
        HOU34255    Parvoviridae       Hamster parvovirus                        4773   19.1   28.1   25.0
                                       Hepatopancreatic parvovirus of penaeid
        AY008257    Parvoviridae       shrimp                                    3350   23.7   22.4   22.7
        HER249437   Parvoviridae       Human erythrovirus V9                     5028   21.0   25.7   23.2
                                       Infectious hypodermal and hematopoietic
        AF218266    Parvoviridae       necrosis virus                            4075   26.3   19.6   21.6
        S47266      Parvoviridae       Junonia coenia densovirus                 5908   27.3   27.3   24.8
        KRU79033    Parvoviridae       Kilham rat virus                          4927   15.1   27.9   23.6
        PARPVRSEQ   Parvoviridae       LuIII virus                               5135   20.1   26.9   23.2
        PARMVMPCG   Parvoviridae       Mice minute virus                         5149   18.5   28.3   24.0
        PARPVMRFD   Parvoviridae       Mink enteritis virus strain Abashiri      5094   27.0   28.5   23.2
        AF495467    Parvoviridae       Minute virus of canines                   5097   21.1   26.2   23.9
        MP12469     Parvoviridae       Mouse parvovirus 1                        5144   18.2   28.5   24.1
        MOU34253    Parvoviridae       Mouse parvovirus 1b                       4764   17.3   28.8   24.5
        MOU34254    Parvoviridae       Mouse parvovirus 1c                       4764   18.5   28.9   24.2
        MDPNSVP     Parvoviridae       Muscovy duck parvovirus                   4550   17.3   23.5   23.8
        AY148187    Parvoviridae       Myzus persicae densovirus                 5499   28.3   25.2   22.4
        AB033596    Parvoviridae       Parvo-like virus                          6542   35.9   29.6   23.8
        PARH1       Parvoviridae       Parvovirus H1                             5176   18.2   29.6   23.5
        AB028936    Parvoviridae       Periplaneta fuliginosa densovirus         5455   29.6   25.7   23.8
        AF221123    Parvoviridae       Pig-tailed macaque parvovirus             5049   28.0   23.9   24.0
        AY032882    Parvoviridae       Planococcus citri densovirus              5380   35.9   23.4   23.6
        PARPOVTRA   Parvoviridae       Porcine parvovirus                        5075   23.2   23.3   21.8
        AF332882    Parvoviridae       Rat minute virus 1a                       4813   14.3   30.6   24.6
        AF332883    Parvoviridae       Rat minute virus 1b                       4816   13.7   29.6   24.5
        AF332884    Parvoviridae       Rat minute virus 1c                       4795   14.3   31.2   24.3




                                                                 Page 35
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


        AF036710    Parvoviridae      Rat parvovirus 1a                          4936   13.9   25.0   24.4
        AF221122    Parvoviridae      Rhesus macaque parvovirus                  5342   22.9   22.8   21.8
        SP26342     Parvoviridae      Simian parvovirus                          4986   20.5   28.3   25.0
        AF201894    Picornaviridae    A-2 plaque virus                           7374   20.3   24.7   24.4
        AB040749    Picornaviridae    Aichi virus                                8280    7.1   19.0   23.6
        BEVVG527    Picornaviridae    Bovine enterovirus                         7414   19.2   23.2   24.0
        AF123432    Picornaviridae    Bovine enterovirus strain K2577            7405   18.2   21.7   24.1
        AF123433    Picornaviridae    Bovine enterovirus strain SL305            7410   18.6   22.4   23.4
        AB084788    Picornaviridae    Bovine kobuvirus                           8374    9.3   20.3   24.2
                                      Echovirus 1 (strain Farouk / ATCC VR-
        AF029859    Picornaviridae    1038)                                      7397   18.5   21.5   23.7
        ECHOV9XX    Picornaviridae    Echovirus 9 (strain Barty)                 7451   19.2   24.0   24.4
        EV9GENOME   Picornaviridae    Echovirus 9 (strain Hill)                  7420   19.4   24.3   24.0
        EVCGAA      Picornaviridae    Encephalomyocarditis virus                 7861   13.7   22.4   24.8
        AF352027    Picornaviridae    Enterovirus 5666/sin/002209                7411   21.5   22.2   23.6
        AF316321    Picornaviridae    Enterovirus 5865/sin/000009                7411   21.3   22.3   23.7
        AF241359    Picornaviridae    Enterovirus CA55-1988                      7411   21.9   24.6   23.7
        AF230973    Picornaviridae    Enterovirus Yanbian 96-83csf               7456   19.5   22.9   22.9
        AF233852    Picornaviridae    Enterovirus Yanbian 96-85csf               7456   19.7   23.0   23.0
        ERPROTYP1   Picornaviridae    Equine rhinitis A virus                    7734   13.2   29.0   24.1
        ERPROTYP2   Picornaviridae    Equine rhinitis B virus                    8828   15.3   23.6   23.2
        AF361253    Picornaviridae    Equine rhinovirus 3                        8821   11.2   25.2   23.5
        FMV7572     Picornaviridae    Foot-and-mouth disease virus               8161   11.4   24.5   24.7
        AF189157    Picornaviridae    Foot-and-mouth disease virus (strain O1)   6996    8.5   24.4   24.1
        FMDVALF     Picornaviridae    Foot-and-mouth disease virus A             7820    9.3   25.7   24.4
        AY304994    Picornaviridae    Foot-and-mouth disease virus Asia 1        8167   10.3   23.6   24.5
        FDI133357   Picornaviridae    Foot-and-mouth disease virus C             8115    9.8   25.0   24.3
        AY317098    Picornaviridae    Foot-and-mouth disease virus HKN/2002      8104   13.1   23.7   24.4
        FOO539140   Picornaviridae    Foot-and-mouth disease virus O             8184    9.6   25.5   24.5
                                      Foot-and-mouth disease virus
        AF377945    Picornaviridae    O/SKR/2000                                 7813    9.9   26.1   23.9
        AF540910    Picornaviridae    Foot-and-mouth disease virus SAT 2         8173   10.7   24.0   24.3
        NCACG       Picornaviridae    Hepatitis A virus                          7478   17.0   26.1   23.5
                                      Hepatitis GB virus BEncephalomyocarditis
        GVI428955   Picornaviridae    virus                                      8027   15.4   20.9   23.5
        AF499635    Picornaviridae    Human coxsackievirus A1                    7397   21.2   25.8   23.3
        AF499636    Picornaviridae    Human coxsackievirus A11                   7453   20.4   23.6   23.3
        AF499637    Picornaviridae    Human coxsackievirus A13                   7458   18.3   26.4   23.1
        AF499638    Picornaviridae    Human coxsackievirus A15                   7441   18.6   26.4   25.1
        CA05876     Picornaviridae    Human coxsackievirus A16                   7413   19.7   24.6   23.7
        AF499639    Picornaviridae    Human coxsackievirus A17                   7457   21.5   23.1   23.4
        AF499640    Picornaviridae    Human coxsackievirus A18                   7458   21.5   27.2   23.5
        AF499641    Picornaviridae    Human coxsackievirus A19                   7410   24.0   24.0   23.2
        AF499642    Picornaviridae    Human coxsackievirus A20                   7436   19.5   24.3   24.3
        AF546702    Picornaviridae    Human coxsackievirus A21                   7406   21.1   26.3   22.6
        AF499643    Picornaviridae    Human coxsackievirus A22                   7406   21.5   25.7   23.9
        CXA24CG     Picornaviridae    Human coxsackievirus A24                   7461   21.4   25.3   24.2
        CXB9CG      Picornaviridae    Human coxsackievirus A9                    7452   19.0   24.4   25.1
        CXB1G       Picornaviridae    Human coxsackievirus B1                    7389   19.2   24.2   24.6
        AF085363    Picornaviridae    Human coxsackievirus B2                    7411   19.0   23.3   23.2
        CV57056     Picornaviridae    Human coxsackievirus B3                    7400   20.4   24.1   24.2
        S76772      Picornaviridae    Human coxsackievirus B4                    7397   19.7   24.7   24.2
        CXB5CGA     Picornaviridae    Human coxsackievirus B5                    7402   22.5   22.8   23.3
        AF105342    Picornaviridae    Human coxsackievirus B6                    7398   19.1   22.8   23.3
        EV11VPCD    Picornaviridae    Human echovirus 11                         7438   19.5   23.9   24.1
        EC12TCGWT   Picornaviridae    Human echovirus 12                         7501   20.1   25.4   24.2
        AF317694    Picornaviridae    Human echovirus 18                         7410   20.5   21.9   24.1
        AY167107    Picornaviridae    Human echovirus 19                         7391   18.0   23.7   23.7
        AF311938    Picornaviridae    Human echovirus 30                         7445   20.8   22.0   24.0
        AF083069    Picornaviridae    Human echovirus 5                          7433   19.3   22.7   24.1
        E616283     Picornaviridae    Human echovirus 6                          7417   17.7   23.2   24.7
        AY036579    Picornaviridae    Human echovirus 7                          7427   19.3   23.6   23.9
        AF524867    Picornaviridae    Human echovirus 9                          7453   19.0   23.9   24.6




                                                                Page 36
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


        EV70CG      Picornaviridae    Human enterovirus 70                           7390   23.0   24.4   24.9
        AF119796    Picornaviridae    Human enterovirus 71                           7436   19.9   22.8   23.2
        AF504533    Picornaviridae    Human enterovirus 73                           7161   20.6   24.4   23.1
        ENT493062   Picornaviridae    Human enterovirus B                            7415   18.5   22.9   23.7
        S45208      Picornaviridae    Human parechovirus 1                           7339   25.8   25.1   24.0
        AF055846    Picornaviridae    Human parechovirus 2                           7352   22.2   24.8   23.6
        AB084913    Picornaviridae    Human parechovirus 3                           7321   24.5   26.8   24.5
        AF538841    Picornaviridae    Human poliovirus 1                             7478   20.5   25.1   23.4
        POLIO1B     Picornaviridae    Human poliovirus 1 Mahoney                     7440   20.0   25.5   23.2
        POLIOS1     Picornaviridae    Human poliovirus 1 strain Sabin                7441   19.6   24.9   23.1
        AF448783    Picornaviridae    Human poliovirus 2                             7441   19.8   25.0   24.7
        HPO293918   Picornaviridae    Human poliovirus 3                             7436   18.2   24.1   24.5
        PI          Picornaviridae    Human rhinovirus 14                            7212   25.0   26.3   24.0
        HRVPP       Picornaviridae    Human rhinovirus 16                            7124   27.7   28.0   23.1
        HRVACG      Picornaviridae    Human rhinovirus 1B                            7133   27.1   26.4   23.7
        HRV89       Picornaviridae    Human rhinovirus 89                            7152   30.6   25.9   23.1
        PIHRV14     Picornaviridae    Human rhinovirus sp.                           7208   24.8   26.6   24.2
        AF538689    Picornaviridae    Ljungan virus                                  7495   20.1   27.2   24.2
        AF327920    Picornaviridae    Ljungan virus prototype strain 87-012          7607   14.1   24.8   24.1
        AF327922    Picornaviridae    Ljungan virus strain 145SL                     7609   15.4   24.8   25.1
        AF327921    Picornaviridae    Ljungan virus strain 174F                      7608   14.6   24.0   23.7
        MNGPOLY     Picornaviridae    Mengo virus                                    7761   12.6   23.2   24.2
        AF363455    Picornaviridae    Porcine enterovirus 10                         7401   19.5   25.3   24.1
        AF406813    Picornaviridae    Porcine enterovirus 8                          7491   23.7   25.6   23.6
        AF363453    Picornaviridae    Porcine enterovirus 9                          7388   20.4   24.1   24.4
        AF296104    Picornaviridae    Porcine teschovirus                            7112   17.0   24.5   24.5
        PEN011380   Picornaviridae    Porcine teschovirus 1                          7117   15.6   23.4   24.4
        SHVAGM27    Picornaviridae    Simian hepatitis A virus                       7400   16.0   27.8   24.5
        AF268065    Picornaviridae    Swine vesicular disease virus                  7406   19.3   22.9   23.4
                                      Swine vesicular disease virus (STRAIN H/3
        SVDG        Picornaviridae    76)                                            7401   17.7   22.0   23.5
        AB090161    Picornaviridae    Theiler-like virus NGS910                      8021   16.4   22.8   23.0
        TMEGDVCG    Picornaviridae    Theilers encephalomyelitis virus               8105   14.5   25.0   25.1
                                      Theilers encephalomyelitis virus (STRAIN
        TMEVCPLT    Picornaviridae    GDVII)                                         8101   14.4   24.9   25.1
        PALPVXX     Polyomaviridae    African green monkey polyomavirus              5270   18.0   25.7   23.1
        PABKVDN     Polyomaviridae    BK polyomavirus                                5153   20.2   25.1   23.6
        PAPPLYBC1   Polyomaviridae    Bovine polyomavirus                            4697   24.4   25.4   24.1
        AF241168    Polyomaviridae    Budgerigar fledgling disease virus - 1         4981   28.3   20.9   23.5
        AF241169    Polyomaviridae    Budgerigar fledgling disease virus - 4         4981   28.1   21.0   23.4
        AF241170    Polyomaviridae    Budgerigar fledgling disease virus - 5         4980   28.3   20.6   23.5
        PAPPLYGE    Polyomaviridae    Budgerigar fledgling polyomavirus              4981   28.5   21.1   23.5
        AY140894    Polyomaviridae    Goose hemorrhagic polyomavirus                 5256   14.0   22.4   24.7
        AB038254    Polyomaviridae    JC virus                                       5234   17.7   24.6   23.1
                                      Mouse polyomavirus (strain Crawford small-
        PAPPYCSP    Polyomaviridae    plaque)                                        5350   15.1   22.2   24.0
        NCVCG       Polyomaviridae    Murine pneumotropic virus                      4754   20.4   26.4   23.7
        PS2CG       Polyomaviridae    Murine polyomavirus strain A2                  5297   15.1   21.0   23.5
        PAPPLY3     Polyomaviridae    Murine polyomavirus strain A3                  5296   14.7   21.1   23.6
        AF442959    Polyomaviridae    Murine polyomavirus strain BG                  5307   14.7   21.4   23.6
        PS27812     Polyomaviridae    Polyomavirus sp.                               5380   14.3   21.7   23.8
        AF332699    Polyomaviridae    Simian virus 40                                5270   18.8   26.0   22.3
        AF250284    Poxviridae        Amsacta moorei entomopoxvirus                232392   44.3   32.0   22.0
        AY009089    Poxviridae        Camelpox virus CMS                           202205   38.1   26.8   22.9
        AF438165    Poxviridae        Camelpox virus M-96                          205719   37.8   26.3   22.9
        AF482758    Poxviridae        Cowpox virus                                 224499   37.7   26.1   23.0
        AF012825    Poxviridae        Ectromelia virus                             209771   38.1   26.4   22.9
        AF198100    Poxviridae        Fowlpox virus                                288539   44.2   27.3   22.5
        AY077836    Poxviridae        Goatpox virus                                149723   35.6   30.2   21.8
        AF409137    Poxviridae        Lumpy skin disease virus                     150793   35.5   29.9   21.9
        AF063866    Poxviridae        Melanoplus sanguinipes entomopoxvirus        236120   41.2   31.5   22.5
        MCU60315    Poxviridae        Molluscum contagiosum virus subtype 1        190289    8.2   22.7   24.0
        AF380138    Poxviridae        Monkeypox virus                              196858   38.2   26.4   23.0




                                                                Page 37
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


        AF170726    Poxviridae        Myxoma virus                                  161773   29.9   22.7   22.1
        AF170722    Poxviridae        Rabbit fibroma virus                          159857   33.0   23.6   21.7
        AY077833    Poxviridae        Sheeppox virus                                150057   35.8   30.2   21.7
        AF410153    Poxviridae        Swinepox virus                                146454   44.8   27.3   22.5
        AY243312    Poxviridae        Vaccinia virus                                194711   37.2   26.2   22.9
        AF095689    Poxviridae        Vaccinia virus (strain Tian Tan)              189274   36.7   26.1   23.0
        PXVARCG     Poxviridae        Variola major virus                           186103   37.6   26.9   23.0
        VMVY16780   Poxviridae        Variola minor virus                           186986   37.8   26.9   23.0
        VVCGAA      Poxviridae        Variola virus                                 185578   37.5   27.0   23.0
        YDI293568   Poxviridae        Yaba-like disease virus                       144575   36.7   30.2   21.3
        AHV3VP2     Reoviridae        African horse sickness virus 1                  3221   25.9   31.0   24.6
        AHVOCPVP2   Reoviridae        African horse sickness virus 4                  3229   23.8   21.8   23.8
        U94887      Reoviridae        African horsesickness virus                     3965   25.1   23.6   24.0
        AF384171    Reoviridae        Avian reovirus strain 1733                      3907   21.1   23.3   23.2
        AB009629    Reoviridae        Avian rotavirus PO-13                           3302   30.9   31.5   23.4
        AF168005    Reoviridae        Banna virus                                     3762   23.3   28.7   25.6
        BTV10VP1    Reoviridae        Bluetongue virus                                3944   26.7   24.1   22.2
        AF529048    Reoviridae        Bluetongue virus 1                              2731   29.6   27.4   22.2
        BTVVP1B     Reoviridae        Bluetongue virus 11                             3944   27.1   22.9   22.1
        BTVVP1C     Reoviridae        Bluetongue virus 13                             3944   27.4   24.6   22.4
        BTVVP1D     Reoviridae        Bluetongue virus 17                             3944   26.4   24.1   22.1
        BTVCOREPR   Reoviridae        Bluetongue virus 2                              3944   28.1   26.0   23.6
        AF529047    Reoviridae        Bluetongue virus 21                             2731   31.9   27.4   22.6
        BTVVP2RC    Reoviridae        Bluetongue virus 23                             2922   28.4   26.0   25.2
        AF529045    Reoviridae        Bluetongue virus 3                              2731   30.2   25.6   22.0
        AF323781    Reoviridae        Bombyx mori cypovirus 1                         4190   32.8   24.1   23.9
        ROBVP1      Reoviridae        Bovine rotavirus                                3302   34.2   27.0   25.2
        AY047488    Reoviridae        Bovine rotavirus B-11                           2352   29.1   31.0   24.7
        AY116592    Reoviridae        Bovine rotavirus RF                             2592   38.4   30.7   25.8
        AF237665    Reoviridae        Bovine Rotavirus Strain Hg18                    2362   30.5   25.8   24.2
        AHU01832    Reoviridae        Broadhaven virus                                3221   25.9   31.0   24.6
        RO1VP45     Reoviridae        Canine rotavirus                                2362   29.4   25.9   21.2
        AF418294    Reoviridae        Chum salmon reovirus CSV                        3947   13.7   21.7   24.2
        AB018086    Reoviridae        Chuzan virus                                    3930   27.9   26.5   23.5
        AF133428    Reoviridae        Colorado tick fever virus                       4350   18.2   24.8   24.4
        AY154458    Reoviridae        Corsican bluetongue virus                       3920   27.3   25.9   23.5
        AY277888    Reoviridae        Cryphonectria parasitica reovirus 9B21          4127   29.3   22.3   25.3
        AY163247    Reoviridae        Dendrolimus punctatus cypovirus 1               4164   33.4   21.5   22.8
        RRNASEG5    Reoviridae        Diadromus pulchellus reovirus                   4230   35.1   24.9   22.5
        S68010      Reoviridae        Epizootic hemorrhagic disease of deer virus     2768   35.8   30.0   22.5
        AB030735    Reoviridae        Epizootic hemorrhagic disease virus             3002   24.7   30.1   22.9
        EHDVP3      Reoviridae        Epizootic hemorrhagic disease virus 1           2791   26.7   24.7   21.7
        EHDSEG2F    Reoviridae        Epizootic hemorrhagic disease virus 2           3003   28.3   25.6   22.8
        RO1VP4P     Reoviridae        Equine rotavirus                                2362   28.4   26.4   23.9
        AF282467    Reoviridae        Eyach virus                                     4349   21.5   25.4   23.1
        RO1VP46     Reoviridae        Feline rotavirus                                2362   29.4   27.1   20.7
        AY029520    Reoviridae        Fiji disease virus                              4532   30.2   28.2   24.2
        AF403398    Reoviridae        Golden shiner reovirus                          3949   12.9   20.5   23.7
        AF284502    Reoviridae        Grass carp hemorrhagic virus                    3877   18.7   21.4   25.4
        AF260511    Reoviridae        Grass carp reovirus                             3949   13.0   20.9   23.1
        HRO303139   Reoviridae        Human rotavirus (group C / strain Bristol)      2736   36.0   27.4   23.5
        AF079356    Reoviridae        Human rotavirus (strain US1205)                 2350   23.0   28.5   24.2
        AB039944    Reoviridae        Human rotavirus 4                               2359   32.6   25.0   23.5
        AB022765    Reoviridae        Human rotavirus A                               3302   32.9   30.0   23.6
        AB037932    Reoviridae        Human rotavirus B                               2847   27.4   28.6   24.2
        AF184084    Reoviridae        Human rotavirus B strain CAL                    2306   31.2   26.7   22.4
        HRO304859   Reoviridae        Human rotavirus C                               3309   34.1   29.3   25.0
        AF401755    Reoviridae        Human rotavirus G2                              2359   24.8   24.6   23.4
        AB008291    Reoviridae        Human rotavirus G3                              2359   32.8   26.8   23.8
        RG30716     Reoviridae        Human rotavirus G9                              2350   30.6   25.3   24.1
        AF361438    Reoviridae        Human rotavirus HMG035                          2362   28.8   25.4   24.0




                                                                 Page 38
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


        ROHK8       Reoviridae        Human rotavirus II type 1                     2359   35.6   28.0   24.7
        AF143408    Reoviridae        Human rotavirus MP409                         2362   25.4   26.5   24.1
        HRO299459   Reoviridae        Human rotavirus SC185                         2359   26.5   25.6   24.1
        AF076926    Reoviridae        Human rotavirus strain NnB1                   2359   22.5   27.6   24.0
        AF076925    Reoviridae        Human rotavirus strain S12/85                 2359   27.1   27.1   25.3
        IA03556     Reoviridae        IDIR agent                                    2341   27.8   26.3   23.6
        AF133429    Reoviridae        Kadipiro virus                                3774   34.2   29.7   24.2
        ROTVP4X     Reoviridae        Lamb rotavirus                                2362   26.7   21.0   23.7
        LRU62152    Reoviridae        Lapine rotavirus                              2362   31.0   26.2   22.9
        AF389462    Reoviridae        Lymantria dispar cypovirus 1                  4164   27.0   26.1   23.0
        AF389452    Reoviridae        Lymantria dispar cypovirus 14                 4329   32.5   24.9   23.3
        AF499925    Reoviridae        Mal de Rio Cuarto virus                       4501   28.7   26.3   25.5
        AF378004    Reoviridae        Mammalian orthoreovirus 1                     3915   26.5   23.7   24.4
        AF378006    Reoviridae        Mammalian orthoreovirus 2                     3915   29.1   22.5   24.6
        REO3L2      Reoviridae        Mammalian orthoreovirus 3                     3916   26.3   22.3   23.4
        MR08424     Reoviridae        Murine rotavirus                              2362   23.5   29.4   22.0
        AF039219    Reoviridae        Murine rotavirus EDIM                         2356   24.4   29.1   24.8
        AF368033    Reoviridae        Ndelle virus                                  3854   27.5   22.1   25.4
        NILIZUMOA   Reoviridae        Nilaparvata lugens reovirus                   4391   32.7   29.3   24.5
        PRVVP1A     Reoviridae        Porcine group C rotavirus                     3290   34.0   26.0   23.8
        PRVP1       Reoviridae        Porcine rotavirus                             3302   34.2   27.7   24.0
        GPRVP1      Reoviridae        Porcine rotavirus strain Gottfried            3302   32.3   29.1   23.7
        RORVP3A     Reoviridae        Rhesus rotavirus                              2362   27.1   27.7   22.4
        RBL294757   Reoviridae        Rice black streaked dwarf virus               4501   24.4   26.8   23.1
        RDVSEG1H    Reoviridae        Rice dwarf virus                              4423   25.9   25.6   24.3
        D86439      Reoviridae        Rice gall dwarf virus                         3514   37.8   28.3   24.6
        AF015682    Reoviridae        Rice ragged stunt virus                       4233   15.9   28.9   24.3
        AB102674    Reoviridae        Rosellinia anti-rot virus                     4143   25.0   22.9   24.5
        GAU65924    Reoviridae        Rotavirus A                                   2362   33.4   26.0   23.9
        ROTROTAB    Reoviridae        Rotavirus B                                   3509   29.6   26.5   23.6
        AF045228    Reoviridae        Rotavirus G8                                  2362   29.2   26.0   24.4
        RO1VP2X     Reoviridae        Rotavirus sp.                                 2693   33.7   27.9   23.0
        AF133431    Reoviridae        Saint Croix river virus                       4089   15.4   20.8   23.8
        AF015955    Reoviridae        Simian rotavirus                              3266   32.3   26.6   24.2
        ROSIVP1     Reoviridae        Simian rotavirus A/SA11                       3302   32.1   27.0   24.5
        TBOBRD2A    Reoviridae        Tick and insect-borne orbivirus               2792   21.5   19.2   23.6
                                      Trichoplusia ni cytoplasmic polyhedrosis
        AF291683    Reoviridae        virus 15                                      4361   35.7   28.5   24.5
        WTVDI       Reoviridae        Wound tumor virus                             2613   34.3   29.1   25.8
        MLOCG       Retroviridae      AKV murine leukemia virus                     8374   12.9   19.9   24.1
        AF411814    Retroviridae      Amphotropic murine leukemia virus             8217   12.7   18.9   22.7
        ALV103J     Retroviridae      Avian leukosis virus                          7841   18.4   23.9   24.0
        AY350569    Retroviridae      Avian leukosis virus LR-9                     7457   15.7   22.8   24.1
        S74099      Retroviridae      Avian myeloblastosis virus                    7226   15.7   23.4   24.4
        MAVTYP1A2   Retroviridae      Avian myeloblastosis-associated virus 1/2     7704   16.6   23.3   24.3
                                      Avian myeloblastosis-associated virus type
        MAVTYP1AA   Retroviridae      1                                             7708   16.2   23.4   24.6
                                      Avian myeloblastosis-associated virus type
        MAVTYP2AA   Retroviridae      2                                             7726   15.5   23.2   24.3
        PSGPE       Retroviridae      Baboon endogenous virus strain M7             8507   16.0   19.6   22.6
        U94514      Retroviridae      Bovine foamy virus                           12002   22.1   21.4   23.3
        BIM127      Retroviridae      Bovine immunodeficiency virus                 8482   16.8   22.0   22.8
        BIMGVPP     Retroviridae      Bovine immunodeficiency-like virus            8388   17.2   22.6   22.8
        RE          Retroviridae      Bovine leukemia virus                         8714   10.2   19.6   23.1
        CEAVCG      Retroviridae      Caprine arthritis-encephalitis virus          9189   22.0   21.8   22.7
        CASBREML    Retroviridae      Cas-Br-E murine leukemia virus                8231   11.2   21.0   22.6
        AF221065    Retroviridae      DG-75 Murine leukemia virus                   8207   12.6   20.3   24.0
                                      Endogenous mouse mammary tumor virus
        AF228550    Retroviridae      Mtv1                                          9851   17.4   24.4   23.5
        AY197548    Retroviridae      Enzootic nasal tumour virus of goats          7448   24.8   26.1   22.9
        AF201902    Retroviridae      Equine foamy virus                           12035   26.5   24.9   24.1
        REEIAVCG    Retroviridae      Equine infectious anemia virus                8407   25.3   25.4   23.0
        AF228552    Retroviridae      Exogenous mouse mammary tumor virus           9895   16.3   23.5   24.1




                                                                Page 39
Endoh et al. Supplement for Table 5                       ProbUniqueVirus


        AB052798    Retroviridae      Feline foamy virus                         11757   23.3   22.8   23.6
        FIU56928    Retroviridae      Feline immunodeficiency virus               9745   25.1   21.9   23.5
        AF052723    Retroviridae      Feline leukemia virus                       8448   15.9   21.7   23.0
        FSU85043    Retroviridae      Feline syncytial virus                     10484   23.0   23.4   23.8
        REFMLVCG    Retroviridae      Friend murine leukemia virus                8359   13.0   21.5   23.1
        U60065      Retroviridae      Gibbon ape leukemia virus (GALV)            8379   12.7   19.5   22.4
        HSA289711   Retroviridae      Homo sapiens (human)HERV-H/env59            7721   14.8   21.7   23.4
        HSA289710   Retroviridae      Homo sapiens (human)HERV-H/env60            7884   11.9   21.9   23.4
        HSA289709   Retroviridae      Homo sapiens (human)HERV-H/env62            8797   11.7   21.1   23.2
                                      Homo sapiens (human)Human endogenous
        AB047209    Retroviridae      retrovirus HERV-K(I)                       11138   15.1   21.9   23.2
                                      Homo sapiens (human)Human endogenous
        AB047240    Retroviridae      retrovirus HERV-K(II)                      11122   15.8   22.8   23.3
        AY208746    Retroviridae      Human endogenous retrovirus HCML-ARV        8412   14.2   23.5   23.3
        AY037928    Retroviridae      Human endogenous retrovirus K113            9472   18.3   22.1   23.3
        AY037929    Retroviridae      Human endogenous retrovirus K115            9463   18.6   21.6   23.6
        HFVHFVCG    Retroviridae      Human foamy virus                          13242   26.6   24.2   24.1
        AF133821    Retroviridae      Human immunodeficiency virus 1             10035   22.1   23.7   23.0
                                      Human immunodeficiency virus 1Homo
        AY352275    Retroviridae      sapiens (human)                            10280   21.1   22.8   22.5
        HIV2CAM2    Retroviridae      Human immunodeficiency virus 2             11443   21.3   21.8   23.0
        HSU21247    Retroviridae      Human spumaretrovirus                      11954   27.6   24.9   24.2
        HTLVCGE     Retroviridae      Human T-cell lymphotropic virus type 2b     8960   11.0   18.6   22.9
        RE1PROP     Retroviridae      Human T-lymphotropic virus 1                9068   13.7   21.4   24.4
        HTCLV2G     Retroviridae      Human T-lymphotropic virus 2                8971    9.9   18.2   23.4
        JDCG        Retroviridae      Jembrana disease virus                      7732   19.5   19.7   22.6
        LD09568     Retroviridae      Lymphoproliferative disease virus           7143   14.9   23.8   23.1
        S51392      Retroviridae      Maedi-Visna-like virus EV1                  9203   22.7   22.5   23.3
        RESIVMPC    Retroviridae      Mason-Pfizer monkey virus                   8557   21.0   23.5   22.4
        AF462057    Retroviridae      Moloney murine leukemia virus               8332   11.2   19.9   22.8
        REMMTPRO    Retroviridae      Mouse mammary tumor virus                  10125   16.8   23.0   23.7
        U43202      Retroviridae      Murine leukemia virus                       8892   12.0   20.1   23.8
        RETCG       Retroviridae      Murine type C retrovirus                    8135   10.9   20.3   23.5
        AF053745    Retroviridae      Mus dunni endogenous virus                  8655   13.0   22.8   23.1
        OEY16627    Retroviridae      Ovine enzootic nasal tumour virus           7434   24.5   25.1   23.7
        OLVSAOMV    Retroviridae      Ovine lentivirus                            9256   25.0   21.0   21.6
        JSRCG       Retroviridae      Ovine pulmonary adenocarcinoma virus        7462   24.3   25.0   22.4
                                      Ovine pulmonary adenocarcinoma virusOvis
        AF357971    Retroviridae      aries (sheep)                              11791   18.6   22.2   23.5
        PEN279056   Retroviridae      Porcine endogenous retrovirus               8918   12.8   21.9   23.4
        AY099323    Retroviridae      Porcine endogenous retrovirus A             8714   13.2   20.9   23.8
        AY099324    Retroviridae      Porcine endogenous retrovirus B             8704   11.7   21.1   23.4
        AF356697    Retroviridae      Porcine endogenous retrovirus E             8072   13.7   20.4   24.6
        PEN293656   Retroviridae      Porcine endogenous type C retrovirus        8918   14.0   22.8   23.9
        PL03982     Retroviridae      Puma lentivirus 14                          9100   27.4   24.2   23.0
        MLVGAG      Retroviridae      Rat leukemia virus                          8107   13.0   20.8   22.9
        ALRCG       Retroviridae      Rous sarcoma virus                          9625   14.3   23.5   24.2
        SF04327     Retroviridae      Simian foamy virus                         13246   25.4   24.4   23.1
        SFVGENOME   Retroviridae      Simian foamy virus type 1                  12972   23.4   25.5   23.6
        SMFPOLORF   Retroviridae      Simian foamy virus type 3                  13111   26.2   24.8   23.7
        SFO544579   Retroviridae      Simian foamy virus-orangutan               12823   23.7   23.7   23.2
        SIVMM239    Retroviridae      Simian immunodeficiency virus              10535   17.8   21.1   23.4
        AY033233    Retroviridae      Simian immunodeficiency virus 17E-Cl       10279   17.8   20.4   23.3
        AY033146    Retroviridae      Simian immunodeficiency virus 17E-Fr       10279   17.8   20.5   23.4
        AF367411    Retroviridae      Simian immunodeficiency virus 2             9518   17.3   21.5   22.7
        SIM549283   Retroviridae      Simian immunodeficiency virus SIVmon        8260   14.8   19.9   22.7
        AF126468    Retroviridae      Simian retrovirus 2                         8105   22.7   24.4   23.9
        REHRDLTR    Retroviridae      Simian sarcoma virus                        8785   15.4   22.8   23.5
        RESIVRV1    Retroviridae      Simian SRV-1 type D retrovirus              8173   21.8   24.7   22.8
        AF074966    Retroviridae      Simian T-lymphotropic virus 1               9028   12.7   20.4   24.2
        STU90557    Retroviridae      Simian T-lymphotropic virus 2               9160   11.4   19.8   23.2
        STLVPH969   Retroviridae      Simian T-lymphotropic virus 3               8919   14.2   19.2   23.8




                                                               Page 40
Endoh et al. Supplement for Table 5                        ProbUniqueVirus


        STU85505    Retroviridae      Simian type D virus 1                         8393   20.3   26.8   22.0
        AF041850    Retroviridae      Simian-Human immunodeficiency virus          10006   19.2   20.7   22.9
        SR26458     Retroviridae      Snakehead retrovirus                         10688   21.2   23.6   23.1
        VLVLV1B     Retroviridae      Visna virus                                   9225   24.6   20.2   22.4
        TYCGAG      Retroviridae      Walleye dermal sarcoma virus                 12708   25.1   25.1   22.3
        AF133051    Retroviridae      Walleye epidermal hyperplasia virus type 1   12999   21.8   25.5   23.8
        AF133052    Retroviridae      Walleye epidermal hyperplasia virus type 2   13125   23.6   24.8   23.5
        AF418014    Rhabdoviridae     Australian bat lyssavirus                    11918   16.5   21.1   23.7
        AF234533    Rhabdoviridae     Bovine ephemeral fever virus                 14900   22.2   26.3   23.5
        AF104985    Rhabdoviridae     Hirame rhabdovirus                           11034   11.8   19.0   23.9
        IHNVRNAGE   Rhabdoviridae     Infectious hematopoietic necrosis virus      11137    9.2   20.2   23.2
        MVNPMGLGE   Rhabdoviridae     Mokola virus                                 11940   18.5   23.3   23.6
        AB030277    Rhabdoviridae     Northern cereal mosaic virus                 13222   22.0   24.3   23.5
        RAVMMGN     Rhabdoviridae     Rabies virus                                 11932   16.9   22.5   23.3
        AB011257    Rhabdoviridae     Rice yellow stunt virus                      14042   22.0   24.6   23.9
        AF147498    Rhabdoviridae     Snakehead rhabdovirus                        11550   12.8   21.1   23.8
        SYENMGL     Rhabdoviridae     Sonchus yellow net virus                     13720   25.3   23.1   24.2
        SVI318079   Rhabdoviridae     Spring viremia of carp virus                 11019   18.4   23.0   23.3
        AF473866    Rhabdoviridae     Vesicular stomatitis Indiana virus           11336   16.8   23.5   24.2
        VHS18263    Rhabdoviridae     Viral hemorrhagic septicemia virus           11158   10.6   19.0   23.1
                                      Viral hemorrhagic septicemia virus (STRAIN
        VHE233396   Rhabdoviridae     07-71)                                       11107   11.2   19.0   23.6
        AF126284    Togaviridae       Aura virus                                   11824   24.3   23.0   22.7
        BFU73745    Togaviridae       Barmah Forest virus                          11488   23.8   22.7   23.5
        AF369024    Togaviridae       Chikungunya virus                            11826   20.0   21.8   23.5
        TOGU01034   Togaviridae       Eastern equine encephalitis virus            11678   21.3   25.1   23.3
        AF079457    Togaviridae       Igbo Ora virus                               11821   22.5   24.2   23.5
        AF237947    Togaviridae       Mayaro virus                                 11411   18.8   23.3   24.2
        SINOCK82    Togaviridae       Ockelbo virus                                11708   18.1   24.7   24.1
        TOGONNPP    Togaviridae       Onyong-nyong virus                           11835   21.4   23.7   23.7
        TOGRRVNB    Togaviridae       Ross River virus                             11657   20.1   23.4   23.5
        AY258323    Togaviridae       Rubella virus                                 9778    7.6   20.1   24.2
        AB032553    Togaviridae       Sagiyama virus                               11698   20.6   22.7   23.1
        SPA316244   Togaviridae       Salmon pancreas disease virus                11919   15.6   22.4   23.7
        SFVRNAIS    Togaviridae       Semliki forest virus                         14529   19.3   23.2   23.2
        SIN         Togaviridae       Sindbis virus                                11703   20.2   23.7   23.7
        SV38304     Togaviridae       Sindbis-like virus                           11717   20.0   23.4   24.5
        AF103734    Togaviridae       Sindbis-like virus YN87448                   11717   19.3   24.4   24.4
        SDI316246   Togaviridae       Sleeping disease virus                       11900   13.7   22.1   24.0
        AF075254    Togaviridae       Venezuelan equine encephalitis virus         11530   19.9   24.9   23.5
        AF214040    Togaviridae       Western equine encephalomyelitis virus       11484   18.9   23.3   23.9




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