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Molecular and Cellular Biology of the Epithelium in Health and

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Molecular and Cellular Biology of the Epithelium in Health and Powered By Docstoc
					                            Faculty of Sciences, University of Lisboa, Portugal

Molecular and Cellular Biology of the Epithelium in Health and Disease
                   Workshops integrated in the Biochemistry PhD programme 2011-12




                                         Deadline for registration: 31 August 2011:
WS1. Membrane Signalling & Inflammation (12-16 Sept)
Faculty:
MD Amaral, University of Lisboa (Portugal); F Antunes, University of Lisboa (Portugal); A Bertorello, Karolinska Institute (Stockholm, Sweden); M
Chanson, University of Geneva (Switzerland); A Jacinto, IMM-Institute of Molecular Medicine, University of Lisboa (Portugal); A Moustakas, Ludvig
Institute of Cancer (Uppsala, Sweden); T Pereira, Karolinska Institute (Stockholm, Sweden); R Tarran, University of Belfast (UK).

Topics:
Epithelia: the basics. Mechanisms of membrane signalling. Cell-to-cell communication. Sodium-sensing networks and their role in disease. TGFß signaling
in development and cancer. Epithelial mesenchymal transitions under the control of TGFß. NF-κB signalling mechanisms. Epithelial morphogenesis and
repair in Drosophila. Mucus clearance and Innate lung defense. Tight junctions, gap junctions and Cystic Fibrosis.


WS2. Epithelial Cell Differentiation, Cilia & Physiology (19-23 Sept)
Faculty:
MD Amaral, University of Lisboa (Portugal); P Aspenström, Karolinska Institute (Stockholm, Sweden); D Brites, University of Lisboa (Portugal); J Fuxe,
Karolinska Institute (Stockholm, Sweden); M Hug, University of Freiburg (Germany); P Jordan, INSA-Portuguese National Institute of Health Lisboa (Portugal);
M Köttgen, University of Freiburg (Germany); K Kunzelmann, University of Regensburg (Germany); P Matos, INSA-Portuguese National Institute of Health
Lisboa (Portugal); T Pereira, Karolinska Institute (Stockholm, Sweden); L Saude, IMM-Institute of Molecular Medicine, University of Lisboa (Portugal).

Topics:
Human epithelia: morphology, cell & tissue differentiation and characterization. Epithelial-mesenchymal transition (EMT) in health and disease. Transcriptional
control of EMT in cancer cell invasion and metastasis. Membrane dynamics and signalling by small GTPases. Signalling by Rho GTPases in cancer and cystic
fibrosis. Physiology of the epithelia in the airways, intestine, pancreas and kidney. Characterization of epithelia by electrophysiological approaches. Patho-
physiology of cystic Fibrosis. Cilia in health and disease. Cilia in vertebrate development. Polycystic kidney disease: from gene to function.



                                         Deadline for registration: 14 October 2011:
WS3. High-Throughput Biology: from Transcriptomics to Functional Genomics
Faculty:                                                  (14-18 Nov 2011)
MD Amaral, University of Lisboa (Portugal); W Balch, Scripps Institute, La Jolla (California, USA); L Clarke, University of Lisboa (Portugal); C Conrad, EMBL,
Heidelberg (Germany); H Florêncio, University of Lisboa (Portugal); R Malhó, University of Lisboa (Portugal); R Pepperkok, EMBL, Heidelberg (Germany)

Topics:
Why using "omic" studies? Transcriptomics. Proteomics and Interactomics. Proteastasis and Secretomics. Functional Genomics: High-Content siRNA & cDNA
Microscopy Screens to Probe Gene Function. Introduction to Systems Biology.

WS4. Bioinformatics and Systems Modelling (21-25 Nov)
Faculty:
M Carvalho, University of Lisboa (Portugal); C Chaouiya, Gulbenkian Institute of Science, Oeiras (Portugal); F Couto, University of Lisboa (Portugal); J-K
Heriché, EMBL, Heidelberg (Germany); S Orchard, EMBL-EBI, Hinxton (UK); F Pinto University of Lisboa (Portugal); J Rung, EMBL-EBI, Hinxton (UK); G
Rustici, EMBL-EBI, Hinxton (UK); G Reither, EMBL, Heidelberg (Germany) J Saez-Rodriguez, EMBL-EBI, Hinxton (UK).

Topics:
Introduction to Biofinformatics. Ensembl: the basics. Gene Ontology. Tools for: 1) transcriptomics (ArrayExpress, Expression Profiler); 2) Proteomics
(UniProt, InterPro, IntAct, PRIDE, PROSITE); 3) Interactomics (STRING). Introduction to pathways modelling for Systems Biology.

                 More information at: http://www.dqb.fc.ul.pt Contact: Renata Vincent [rrvincent@fc.ul.pt]

				
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posted:12/4/2011
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