Supplementary table 4
Genes involved in the process of angiogenesis
fold change
50 high
probeset.id description Gene Symbol
versus 50
low samples
GNAI3 polypeptide 3
201180_s_at guanine nucleotide binding protein (G protein), alpha inhibiting activity1.1555
211148_s_at angiopoietin 2 ANGPT2 1.3701
205746_s_at ADAM metallopeptidase domain 17 (tumor necrosis ADAM17 1.4301
factor, alpha, converting enzyme)
215561_s_at interleukin 1 receptor, type I IL1R1 1.3125
214168_s_at tight junction protein 1 (zona occludens 1) TJP1 1.3611
MAP3K7IP2
210284_s_at mitogen-activated protein kinase kinase kinase 7 interacting protein 2 1.2054
203265_s_at mitogen-activated protein kinase kinase 4 MAP2K4 1.1802
212777_at son of sevenless homolog 1 (Drosophila) SOS1 1.2715
(Noonan
209895_at protein tyrosine phosphatase, non-receptor type 11PTPN11 syndrome1.2213 1)
214732_at Sp1 transcription factor SP1 1.1530
204271_s_at endothelin receptor type B EDNRB 1.5701
MALT1
210018_x_at mucosa associated lymphoid tissue lymphoma translocation gene 1 1.3143
203076_s_at SMAD family member 2 SMAD2 1.1795
212870_at Ras association (RalGDS/AF-6) domain family 3 RASSF3 1.2278
211665_s_at son of sevenless homolog 2 (Drosophila) SOS2 1.4256
205841_at Janus kinase 2 (a protein tyrosine kinase) JAK2 1.4084
NFKB2 1.6150
207535_s_at nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
204725_s_at NCK adaptor protein 1 NCK1 1.5882
ARTS-1
210385_s_at type 1 tumor necrosis factor receptor shedding aminopeptidase regulator 1.7837
203809_s_at v-akt murine thymoma viral oncogene homolog 2 AKT2 1.1373
200879_s_at endothelial PAS domain protein 1 EPAS1 1.3240
201808_s_at endoglin (Osler-Rendu-Weber syndrome 1) ENG 1.1839
RELA 1.3714
209878_s_at v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide
SHC1
201469_s_at SHC (Src homology 2 domain containing) transforming protein 1 1.5735
MAPKAPK2
201461_s_at mitogen-activated protein kinase-activated protein kinase 2 1.5052
208853_s_at calnexin CANX 1.3823
210449_x_at mitogen-activated protein kinase 14 MAPK14 1.3312
209941_at receptor (TNFRSF)-interacting serine-threonine kinase 1RIPK1 1.5427
208351_s_at mitogen-activated protein kinase 1 MAPK1 1.6056
STAT3 1.7063
208992_s_at signal transducer and activator of transcription 3 (acute-phase response factor)
TGFBR2
207334_s_at transforming growth factor, beta receptor II (70/80kDa) 1.4774
signal transducer and
AFFX-HUMISGF3A/M97935_MA_at activator of transcription 1, 91kDa STAT1 2.1668
203935_at activin A receptor, type I ACVR1 1.5192
KDR
203934_at kinase insert domain receptor (a type III receptor tyrosine kinase) 1.5994
209189_at v-fos FBJ murine osteosarcoma viral oncogene homolog FOS 3.3671
212298_at neuropilin 1 NRP1 2.1366
203989_x_at coagulation factor II (thrombin) receptor F2R 1.6519
201261_x_at biglycan BGN 1.4951
221773_at ELK3, ETS-domain protein (SRF accessory protein 2) ELK3 1.6625
211924_s_at plasminogen activator, urokinase receptor PLAUR 2.2398
NFKB1
209239_at nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) 1.7650
200839_s_at cathepsin B CTSB 1.7407
216598_s_at chemokine (C-C motif) ligand 2 CCL2 3.0075
PDE4B 3.7987
203708_at phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
206978_at chemokine (C-C motif) receptor 2 CCR2 2.0664
214560_at formyl peptide receptor-like 2 FPRL2 2.7752
ITGA4
213416_at integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2.9869
209906_at complement component 3a receptor 1 C3AR1 2.5240
205098_at chemokine (C-C motif) receptor 1 CCR1 2.9218
38487_at stabilin 1 STAB1 2.1010
CXCL12
203666_at chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) 2.7103
209101_at connective tissue growth factor CTGF 2.0972
201289_at cysteine-rich, angiogenic inducer, 61 CYR61 1.9762
210495_x_at fibronectin 1 FN1 2.7347
212667_at secreted protein, acidic, cysteine-rich (osteonectin) SPARC 2.3808
SERPINF1 4.2367
202283_at serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), m
203868_s_at vascular cell adhesion molecule 1 VCAM1 4.8383
MMP2 2.0739
201069_at matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
204575_s_at matrix metallopeptidase 19 MMP19 2.4023
SERPINE1 3.0971
202627_s_at serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
204464_s_at endothelin receptor type A EDNRA 2.2347
203821_at heparin-binding EGF-like growth factor HBEGF 2.2903
205935_at forkhead box F1 FOXF1 1.4614
201162_at insulin-like growth factor binding protein 7 IGFBP7 1.4601
GNAI2 polypeptide 2
201040_at guanine nucleotide binding protein (G protein), alpha inhibiting activity1.3706
200059_s_at ras homolog gene family, member A RHOA 1.2602
201107_s_at thrombospondin 1 THBS1 1.4211
208850_s_at Thy-1 cell surface antigen THY1 1.8175
REL
206036_s_at v-rel reticuloendotheliosis viral oncogene homolog (avian) 1.4580
200737_at phosphoglycerate kinase 1 PGK1 1.3791
209677_at protein kinase C, iota PRKCI 1.6577
205778_at kallikrein-related peptidase 7 KLK7 2.4687
203683_s_at vascular endothelial growth factor B VEGFB 1.2958
202898_at syndecan 3 SDC3 1.3487
213490_s_at mitogen-activated protein kinase kinase 2 MAP2K2 1.1583
SREBF2
201248_s_at sterol regulatory element binding transcription factor 2 1.1947
209098_s_at jagged 1 (Alagille syndrome) JAG1 1.5207
210361_s_at E74-like factor 2 (ets domain transcription factor) ELF2 1.1630
Genes involved in the process of apoptosis
fold change
50 high
probeset.id description Gene Symbol
versus 50
low samples
HSPA5
211936_at heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.177
factor, alpha, converting enzyme)
205746_s_at ADAM metallopeptidase domain 17 (tumor necrosis ADAM17 1.430
210222_s_at reticulon 1 RTN1 1.514
215990_s_at B-cell CLL/lymphoma 6 (zinc finger protein 51) BCL6 1.413
207098_s_at mitofusin 1 MFN1 1.223
222343_at BCL2-like 11 (apoptosis facilitator) BCL2L11 1.187
212777_at son of sevenless homolog 1 (Drosophila) SOS1 1.272
203076_s_at SMAD family member 2 SMAD2 1.180
AIFM1
205512_s_at apoptosis-inducing factor, mitochondrion-associated, 1 1.246
209321_s_at adenylate cyclase 3 ADCY3 1.430
202670_at mitogen-activated protein kinase kinase 1 MAP2K1 1.353
205841_at Janus kinase 2 (a protein tyrosine kinase) JAK2 1.408
TNFRSF21
214581_x_at tumor necrosis factor receptor superfamily, member 21 1.825
GNAI2 1.371
201040_at guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
10
202688_at tumor necrosis factor (ligand) superfamily, memberTNFSF10 2.576
13
211495_x_at tumor necrosis factor (ligand) superfamily, memberTNFSF13 1.765
204908_s_at B-cell CLL/lymphoma 3 BCL3 2.407
210101_x_at SH3-domain GRB2-like endophilin B1 SH3GLB1 1.696
203821_at heparin-binding EGF-like growth factor HBEGF 2.290
200798_x_at myeloid cell leukemia sequence 1 (BCL2-related) MCL1 1.987
206150_at CD27 molecule CD27 1.814
NFKB1
209239_at nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) 1.765
215223_s_at superoxide dismutase 2, mitochondrial SOD2 3.242
203508_at tumor necrosis factor receptor superfamily, member 1B TNFRSF1B 2.154
CYBB
203922_s_at cytochrome b-245, beta polypeptide (chronic granulomatous disease) 3.069
NCF2 2.758
209949_at neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)
CSF2RB 3.446
205159_at colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
NCF1
204961_s_at neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)2.085
CASP1 3.681
211368_s_at caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
203085_s_at transforming growth factor, beta 1 TGFB1 2.581
213418_at heat shock 70kDa protein 6 (HSP70B') HSPA6 2.120
215719_x_at Fas (TNF receptor superfamily, member 6) FAS 2.501
201471_s_at sequestosome 1 SQSTM1 1.566
216442_x_at fibronectin 1 FN1 2.715
INHBA
210511_s_at inhibin, beta A (activin A, activin AB alpha polypeptide) 3.481
208351_s_at mitogen-activated protein kinase 1 MAPK1 1.606
YWHAH 1.738
201020_at tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
ARTS-1
210385_s_at type 1 tumor necrosis factor receptor shedding aminopeptidase regulator 1.784
200766_at cathepsin D CTSD 1.708
NFKB2 1.615
207535_s_at nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
209189_at v-fos FBJ murine osteosarcoma viral oncogene homolog FOS 3.367
REL
206036_s_at v-rel reticuloendotheliosis viral oncogene homolog (avian) 1.458
KDR
203934_at kinase insert domain receptor (a type III receptor tyrosine kinase) 1.599
203843_at ribosomal protein S6 kinase, 90kDa, polypeptide 3 RPS6KA3 1.525
206536_s_at baculoviral IAP repeat-containing 4 BIRC4 1.306
200803_s_at testis enhanced gene transcript (BAX inhibitor 1) TEGT 1.278
211833_s_at BCL2-associated X protein BAX 1.428
213490_s_at mitogen-activated protein kinase kinase 2 MAP2K2 1.158
IKBKB
211027_s_at inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.200
YWHAZ 1.381
200638_s_at tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
206665_s_at BCL2-like 1 BCL2L1 1.333
NAPA
206491_s_at N-ethylmaleimide-sensitive factor attachment protein, alpha 1.336
210338_s_at heat shock 70kDa protein 8 HSPA8 1.166
211016_x_at heat shock 70kDa protein 4 HSPA4 1.372
217140_s_at voltage-dependent anion channel 1 VDAC1 1.357
PPP2CA
208652_at protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 1.258
210449_x_at mitogen-activated protein kinase 14 MAPK14 1.331
209941_at receptor (TNFRSF)-interacting serine-threonine kinase 1RIPK1 1.543
SHC1
201469_s_at SHC (Src homology 2 domain containing) transforming protein 1 1.573
TGFBR2
207334_s_at transforming growth factor, beta receptor II (70/80kDa) 1.477
201101_s_at BCL2-associated transcription factor 1 BCLAF1 1.306
alpha (tissue specific extinguisher 1)
200604_s_at protein kinase, cAMP-dependent, regulatory, type I,PRKAR1A 1.315
216205_s_at mitofusin 2 MFN2 1.312
PPP2R1B
202886_s_at protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform1.820
207686_s_at caspase 8, apoptosis-related cysteine peptidase CASP8 1.640
RELA 1.371
209878_s_at v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide
1861_at BCL2-antagonist of cell death BAD 1.392
203809_s_at v-akt murine thymoma viral oncogene homolog 2 AKT2 1.137
208485_x_at CASP8 and FADD-like apoptosis regulator CFLAR 1.479
212870_at Ras association (RalGDS/AF-6) domain family 3 RASSF3 1.228
211665_s_at son of sevenless homolog 2 (Drosophila) SOS2 1.426
203265_s_at mitogen-activated protein kinase kinase 4 MAP2K4 1.180
202076_at baculoviral IAP repeat-containing 2 BIRC2 1.148
GNAI3 1.156
201180_s_at guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
201464_x_at jun oncogene JUN 1.301
Genes involved in the process of cell cycle
fold change
50 high
probeset.id description Gene Symbol
versus 50
low samples
215990_s_at B-cell CLL/lymphoma 6 (zinc finger protein 51) BCL6 1.413
209331_s_at MYC associated factor X MAX 1.165
212347_x_at MAX dimerization protein 4 MXD4 1.213
204147_s_at transcription factor Dp-1 TFDP1 1.206
203418_at cyclin A2 CCNA2 1.574
202647_s_at neuroblastoma RAS viral (v-ras) oncogene homologNRAS 1.312
GNAI3 1.337
201179_s_at guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
200622_x_at calmodulin 3 (phosphorylase kinase, delta) CALM3 1.254
203079_s_at cullin 2 CUL2 1.144
211578_s_at ribosomal protein S6 kinase, 70kDa, polypeptide 1 RPS6KB1 1.318
(Noonan
209895_at protein tyrosine phosphatase, non-receptor type 11PTPN11 syndrome 1) 1.221
212777_at son of sevenless homolog 1 (Drosophila) SOS1 1.272
203265_s_at mitogen-activated protein kinase kinase 4 MAP2K4 1.180
221381_s_at mortality factor 4 MORF4 1.180
202670_at mitogen-activated protein kinase kinase 1 MAP2K1 1.353
215561_s_at interleukin 1 receptor, type I IL1R1 1.313
211665_s_at son of sevenless homolog 2 (Drosophila) SOS2 1.426
212870_at Ras association (RalGDS/AF-6) domain family 3 RASSF3 1.228
IL6ST
211000_s_at interleukin 6 signal transducer (gp130, oncostatin M receptor) 1.650
IKBKB
211027_s_at inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.200
213490_s_at mitogen-activated protein kinase kinase 2 MAP2K2 1.158
STAT6
201332_s_at signal transducer and activator of transcription 6, interleukin-4 induced 1.351
RELA 1.371
209878_s_at v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide
210449_x_at mitogen-activated protein kinase 14 MAPK14 1.331
208853_s_at calnexin CANX 1.382
202162_s_at CCR4-NOT transcription complex, subunit 8 CNOT8 1.199
SHC1
201469_s_at SHC (Src homology 2 domain containing) transforming protein 1 1.573
alpha (tissue specific extinguisher 1)
200604_s_at protein kinase, cAMP-dependent, regulatory, type I,PRKAR1A 1.315
214732_at Sp1 transcription factor SP1 1.153
207629_s_at rho/rac guanine nucleotide exchange factor (GEF) 2ARHGEF2 1.183
205409_at FOS-like antigen 2 FOSL2 1.561
203751_x_at jun D proto-oncogene JUND 1.467
201367_s_at zinc finger protein 36, C3H type-like 2 ZFP36L2 1.761
210428_s_at hepatocyte growth factor-regulated tyrosine kinase HGSsubstrate 1.212
203809_s_at v-akt murine thymoma viral oncogene homolog 2 AKT2 1.137
31845_at E74-like factor 4 (ets domain transcription factor) ELF4 1.652
206536_s_at baculoviral IAP repeat-containing 4 BIRC4 1.306
200675_at CD81 molecule CD81 1.211
210510_s_at neuropilin 1 NRP1 1.714
214667_s_at tumor protein p53 inducible protein 11 TP53I11 1.199
203683_s_at vascular endothelial growth factor B VEGFB 1.296
212143_s_at insulin-like growth factor binding protein 3 IGFBP3 1.837
201666_at TIMP metallopeptidase inhibitor 1 TIMP1 1.646
205945_at interleukin 6 receptor IL6R 1.902
GNAI2 1.371
201040_at guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
201508_at insulin-like growth factor binding protein 4 IGFBP4 1.686
216235_s_at endothelin receptor type A EDNRA 1.531
INHBA
210511_s_at inhibin, beta A (activin A, activin AB alpha polypeptide) 3.481
209651_at transforming growth factor beta 1 induced transcript 1 TGFB1I1 2.216
208944_at transforming growth factor, beta receptor II (70/80kDa)TGFBR2 1.838
201162_at insulin-like growth factor binding protein 7 IGFBP7 1.460
203989_x_at coagulation factor II (thrombin) receptor F2R 1.652
204457_s_at growth arrest-specific 1 GAS1 2.680
205729_at oncostatin M receptor OSMR 2.860
211612_s_at interleukin 13 receptor, alpha 1 IL13RA1 2.371
13
209499_x_at tumor necrosis factor (ligand) superfamily, memberTNFSF13 1.941
204533_at chemokine (C-X-C motif) ligand 10 CXCL10 5.175
signal transducer and
AFFX-HUMISGF3A/M97935_MB_at activator of transcription 1, 91kDa STAT1 2.225
200628_s_at tryptophanyl-tRNA synthetase WARS 1.902
NFKB1 1.765
209239_at nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
201473_at jun B proto-oncogene JUNB 2.331
203085_s_at transforming growth factor, beta 1 TGFB1 2.581
205114_s_at chemokine (C-C motif) ligand 3 CCL3 2.777
203508_at tumor necrosis factor receptor superfamily, member 1B TNFRSF1B 2.154
204103_at chemokine (C-C motif) ligand 4 CCL4 3.307
213095_x_at allograft inflammatory factor 1 AIF1 2.130
205098_at chemokine (C-C motif) receptor 1 CCR1 2.922
CSF1R 2.772
203104_at colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncoge
204912_at interleukin 10 receptor, alpha IL10RA 3.047
210895_s_at CD86 molecule CD86 3.478
209906_at complement component 3a receptor 1 C3AR1 2.524
212588_at protein tyrosine phosphatase, receptor type, C PTPRC 4.239
213160_at dedicator of cytokinesis 2 DOCK2 2.941
IL2RG
204116_at interleukin 2 receptor, gamma (severe combined immunodeficiency) 2.760
201141_at glycoprotein (transmembrane) nmb GPNMB 3.077
SLAMF1
206181_at signaling lymphocytic activation molecule family member 1 1.382
206978_at chemokine (C-C motif) receptor 2 CCR2 2.066
206150_at CD27 molecule CD27 1.814
202531_at interferon regulatory factor 1 IRF1 2.343
CXCL12
203666_at chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) 2.710
204039_at CCAAT/enhancer binding protein (C/EBP), alpha CEBPA 1.363
201648_at Janus kinase 1 (a protein tyrosine kinase) JAK1 1.375
210563_x_at CASP8 and FADD-like apoptosis regulator CFLAR 1.633
209716_at colony stimulating factor 1 (macrophage) CSF1 1.706
205842_s_at Janus kinase 2 (a protein tyrosine kinase) JAK2 1.582
217739_s_at pre-B-cell colony enhancing factor 1 PBEF1 1.704
212271_at mitogen-activated protein kinase 1 MAPK1 1.561
KDR
203934_at kinase insert domain receptor (a type III receptor tyrosine kinase) 1.599
203167_at TIMP metallopeptidase inhibitor 2 TIMP2 1.530
REL
206036_s_at v-rel reticuloendotheliosis viral oncogene homolog (avian) 1.458
204725_s_at NCK adaptor protein 1 NCK1 1.588
202768_at FBJ murine osteosarcoma viral oncogene homolog B FOSB 2.530
201236_s_at BTG family, member 2 BTG2 1.386
201464_x_at jun oncogene JUN 1.301
ADAMTS1
222162_s_at ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.911
201853_s_at cell division cycle 25 homolog B (S. pombe) CDC25B 1.316
Genes involved in the process of immune response
fold change
50 high
probeset.id description Gene Symbol
versus 50
low samples
201058_s_at myosin, light chain 9, regulatory MYL9 1.425
200931_s_at vinculin VCL 1.318
PTGS1
215813_s_at prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and1.658 cyclooxygenase)
211699_x_at hemoglobin, alpha 1 HBA1 1.830
MALT1
210018_x_at mucosa associated lymphoid tissue lymphoma translocation gene 1 1.314
221528_s_at engulfment and cell motility 2 ELMO2 1.173
HSPA5
211936_at heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.177
208612_at protein disulfide isomerase family A, member 3 PDIA3 1.202
203751_x_at jun D proto-oncogene JUND 1.467
201464_x_at jun oncogene JUN 1.301
ITGB3
204627_s_at integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.531
215990_s_at B-cell CLL/lymphoma 6 (zinc finger protein 51) BCL6 1.413
209051_s_at ral guanine nucleotide dissociation stimulator RALGDS 1.258
212870_at Ras association (RalGDS/AF-6) domain family 3 RASSF3 1.228
207332_s_at transferrin receptor (p90, CD71) TFRC 1.575
200613_at adaptor-related protein complex 2, mu 1 subunit AP2M1 1.260
201532_at proteasome (prosome, macropain) subunit, alpha type, 3 PSMA3 1.147
203254_s_at talin 1 TLN1 1.373
205778_at kallikrein-related peptidase 7 KLK7 2.469
200675_at CD81 molecule CD81 1.211
209575_at interleukin 10 receptor, beta IL10RB 1.433
205746_s_at ADAM metallopeptidase domain 17 (tumor necrosis ADAM17 factor, alpha, converting enzyme)
1.430
208850_s_at Thy-1 cell surface antigen THY1 1.818
217279_x_at matrix metallopeptidase 14 (membrane-inserted) MMP14 1.212
LRP1
200784_s_at low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) 1.199
MAP3K7IP2
210284_s_at mitogen-activated protein kinase kinase kinase 7 interacting protein 2 1.205
(Noonan
209895_at protein tyrosine phosphatase, non-receptor type 11PTPN11 syndrome 1) 1.221
ABCC1
202805_s_at ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.234
STAT6
201332_s_at signal transducer and activator of transcription 6, interleukin-4 induced 1.351
213490_s_at mitogen-activated protein kinase kinase 2 MAP2K2 1.158
IKBKB
211027_s_at inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta1.200
211823_s_at paxillin PXN 1.190
203311_s_at ADP-ribosylation factor 6 ARF6 1.402
214732_at Sp1 transcription factor SP1 1.153
217234_s_at villin 2 (ezrin) VIL2 1.547
207686_s_at caspase 8, apoptosis-related cysteine peptidase CASP8 1.640
212220_at proteasome (prosome, macropain) activator subunit 4 PSME4 1.301
210362_x_at promyelocytic leukemia PML 1.327
213446_s_at IQ motif containing GTPase activating protein 1 IQGAP1 2.012
210338_s_at heat shock 70kDa protein 8 HSPA8 1.166
211016_x_at heat shock 70kDa protein 4 HSPA4 1.372
PSME3
200987_x_at proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.354
DUSP3
201537_s_at dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) 1.657
211665_s_at son of sevenless homolog 2 (Drosophila) SOS2 1.426
206665_s_at BCL2-like 1 BCL2L1 1.333
STAT2
205170_at signal transducer and activator of transcription 2, 113kDa 1.481
214040_s_at gelsolin (amyloidosis, Finnish type) GSN 1.583
RELA
209878_s_at v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide
1.371
RIPK1
209941_at receptor (TNFRSF)-interacting serine-threonine kinase 1 1.543
204109_s_at nuclear transcription factor Y, alpha NFYA 1.240
210449_x_at mitogen-activated protein kinase 14 MAPK14 1.331
210904_s_at interleukin 13 receptor, alpha 1 IL13RA1 2.523
218748_s_at exocyst complex component 5 EXOC5 1.452
209131_s_at synaptosomal-associated protein, 23kDa SNAP23 1.669
214895_s_at ADAM metallopeptidase domain 10 ADAM10 1.602
208853_s_at calnexin CANX 1.382
YWHAZ
200641_s_at tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
1.548
201399_s_at translocation associated membrane protein 1 TRAM1 1.504
actin, beta
AFFX-HSAC07/X00351_5_at ACTB 1.714
MAPKAPK2
201461_s_at mitogen-activated protein kinase-activated protein kinase 2 1.505
SHC1
201469_s_at SHC (Src homology 2 domain containing) transforming protein 1 1.573
GNA13
206917_at guanine nucleotide binding protein (G protein), alpha 13 1.400
210974_s_at adaptor-related protein complex 3, delta 1 subunit AP3D1 1.202
alpha (tissue specific extinguisher 1)
200604_s_at protein kinase, cAMP-dependent, regulatory, type I,PRKAR1A 1.315
GNB1
200744_s_at guanine nucleotide binding protein (G protein), beta polypeptide 1 1.452
203809_s_at v-akt murine thymoma viral oncogene homolog 2 AKT2 1.137
1861_at BCL2-antagonist of cell death BAD 1.392
204969_s_at radixin RDX 1.289
209677_at protein kinase C, iota PRKCI 1.658
208478_s_at BCL2-associated X protein BAX 1.247
209999_x_at suppressor of cytokine signaling 1 SOCS1 1.192
PSMD1
201198_s_at proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.245
201274_at proteasome (prosome, macropain) subunit, alpha type, 5PSMA5 1.209
GNAI3
201180_s_at guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
1.156
GNAI3
201179_s_at guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
1.337
203418_at cyclin A2 CCNA2 1.574
PSMD12
202352_s_at proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.207
202670_at mitogen-activated protein kinase kinase 1 MAP2K1 1.353
205084_at B-cell receptor-associated protein 29 BCAP29 1.598
217094_s_at itchy homolog E3 ubiquitin protein ligase (mouse) ITCH 1.281
PPP3R1
204507_s_at protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform1.324
222343_at BCL2-like 11 (apoptosis facilitator) BCL2L11 1.187
200622_x_at calmodulin 3 (phosphorylase kinase, delta) CALM3 1.254
203530_s_at syntaxin 4 STX4 1.393
2 (avian)
201329_s_at v-ets erythroblastosis virus E26 oncogene homolog ETS2 1.429
PPP2CA
208652_at protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 1.258
207808_s_at protein S (alpha) PROS1 1.648
201666_at TIMP metallopeptidase inhibitor 1 TIMP1 1.646
200983_x_at CD59 molecule, complement regulatory protein CD59 1.532
GNAI2
201040_at guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
1.371
200059_s_at ras homolog gene family, member A RHOA 1.260
203989_x_at coagulation factor II (thrombin) receptor F2R 1.652
MARCKS
201669_s_at myristoylated alanine-rich protein kinase C substrate 1.543
218880_at FOS-like antigen 2 FOSL2 2.007
SERPING1
200986_at serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
1.589
205945_at interleukin 6 receptor IL6R 1.902
214508_x_at cAMP responsive element modulator CREM 1.377
202716_at protein tyrosine phosphatase, non-receptor type 1 PTPN1 1.330
214702_at fibronectin 1 FN1 2.712
211160_x_at actinin, alpha 1 ACTN1 1.309
211926_s_at myosin, heavy chain 9, non-muscle MYH9 1.740
208351_s_at mitogen-activated protein kinase 1 MAPK1 1.606
YWHAH
201020_at tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
1.738
217475_s_at LIM domain kinase 2 LIMK2 1.709
211075_s_at CD47 molecule CD47 2.047
209716_at colony stimulating factor 1 (macrophage) CSF1 1.706
211676_s_at interferon gamma receptor 1 IFNGR1 1.851
204039_at CCAAT/enhancer binding protein (C/EBP), alpha CEBPA 1.363
200798_x_at myeloid cell leukemia sequence 1 (BCL2-related) MCL1 1.987
204438_at mannose receptor, C type 1 MRC1 2.303
216252_x_at Fas (TNF receptor superfamily, member 6) FAS 2.308
214366_s_at arachidonate 5-lipoxygenase ALOX5 2.060
201212_at legumain LGMN 1.715
211635_x_at netrin 2-like (chicken) NTN2L 2.078
209374_s_at immunoglobulin heavy constant mu IGHM 3.129
214916_x_at interleukin 8 IL8 2.555
217148_x_at immunoglobulin lambda locus IGL@ 2.512
211633_x_at immunoglobulin heavy constant gamma 1 (G1m marker) IGHG1 2.099
216542_x_at coagulation factor XIII, B polypeptide F13B 1.553
211641_x_at NA NA 1.811
216557_x_at interferon, alpha-inducible protein 6 IFI6 2.048
217157_x_at NA NA 1.936
211643_x_at major histocompatibility complex, class I, C HLA-C 2.263
LOC652128
211637_x_at similar to Ig heavy chain V-II region ARH-77 precursor 2.809
216576_x_at major histocompatibility complex, class I, C HLA-C 3.340
IGHG1
217236_x_at immunoglobulin heavy constant gamma 1 (G1m marker) 1.266
206978_at chemokine (C-C motif) receptor 2 CCR2 2.066
SH2D1A
210116_at SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome) 1.570
211339_s_at IL2-inducible T-cell kinase ITK 2.133
211668_s_at plasminogen activator, urokinase PLAU 4.507
216442_x_at fibronectin 1 FN1 2.715
200974_at actin, alpha 2, smooth muscle, aorta ACTA2 2.615
MMP2
201069_at matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
2.074
208131_s_at prostaglandin I2 (prostacyclin) synthase PTGIS 2.404
SERPINE1
202628_s_at serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
3.302
CXCL12
209687_at chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) 4.278
CXCL12
203666_at chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) 2.710
ICAM1
202637_s_at intercellular adhesion molecule 1 (CD54), human rhinovirus receptor 3.010
ICAM1
202638_s_at intercellular adhesion molecule 1 (CD54), human rhinovirus receptor 3.789
211924_s_at plasminogen activator, urokinase receptor PLAUR 2.240
GBP1
202270_at guanylate binding protein 1, interferon-inducible, 67kDa 2.915
203085_s_at transforming growth factor, beta 1 TGFB1 2.581
200600_at moesin MSN 1.922
202625_at v-yes-1 Yamaguchi sarcoma viral related oncogene LYN homolog 2.373
203868_s_at vascular cell adhesion molecule 1 VCAM1 4.838
202531_at interferon regulatory factor 1 IRF1 2.343
214038_at chemokine (C-C motif) ligand 8 CCL8 3.215
211122_s_at chemokine (C-X-C motif) ligand 11 CXCL11 5.293
204533_at chemokine (C-X-C motif) ligand 10 CXCL10 5.175
203915_at chemokine (C-X-C motif) ligand 9 CXCL9 3.897
208829_at TAP binding protein (tapasin) TAPBP 2.025
PSMB9
204279_at proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
3.089
216231_s_at beta-2-microglobulin B2M 1.691
200905_x_at major histocompatibility complex, class I, E HLA-E 1.921
211530_x_at HLA-G histocompatibility antigen, class I, G HLA-G 1.680
208812_x_at major histocompatibility complex, class I, C HLA-C 1.836
210514_x_at HLA-G histocompatibility antigen, class I, G HLA-G 1.707
208729_x_at major histocompatibility complex, class I, B HLA-B 2.231
204806_x_at major histocompatibility complex, class I, F HLA-F 2.114
215313_x_at major histocompatibility complex, class I, A HLA-A 1.809
1
212998_x_at major histocompatibility complex, class II, DQ beta HLA-DQB1 4.120
HLA-DQA1
212671_s_at major histocompatibility complex, class II, DQ alpha 1 4.697
217478_s_at major histocompatibility complex, class II, DM alphaHLA-DMA 2.731
CD74
209619_at CD74 molecule, major histocompatibility complex, class II invariant chain 2.789
5
204670_x_at major histocompatibility complex, class II, DR beta HLA-DRB5 2.608
1
215193_x_at major histocompatibility complex, class II, DR beta HLA-DRB1 3.135
208894_at major histocompatibility complex, class II, DR alpha HLA-DRA 2.927
1
201137_s_at major histocompatibility complex, class II, DP beta HLA-DPB1 2.606
213537_at major histocompatibility complex, class II, DP alpha 1HLA-DPA1 4.716
FCGR3B
204006_s_at Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 3.964
F
210889_s_at Fc fragment of IgG, low affinity IIb, receptor (CD32) CGR2B 3.071
IL2RG
204116_at interleukin 2 receptor, gamma (severe combined immunodeficiency) 2.760
LILRB4
210152_at leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
2.311
209083_at coronin, actin binding protein, 1A CORO1A 3.003
214770_at macrophage scavenger receptor 1 MSR1 2.751
202902_s_at cathepsin S CTSS 3.180
204057_at interferon regulatory factor 8 IRF8 2.307
CSF2RB
205159_at colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
3.446
ITGB2
202803_s_at integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3.479
NCF2
209949_at neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)
2.758
205098_at chemokine (C-C motif) receptor 1 CCR1 2.922
F
203561_at Fc fragment of IgG, low affinity IIa, receptor (CD32) CGR2A 2.974
F
216950_s_at Fc fragment of IgG, high affinity Ia, receptor (CD64) CGR1A 3.099
204924_at toll-like receptor 2 TLR2 2.564
ADAMTS10
213733_at ADAM metallopeptidase with thrombospondin type 1 motif, 10 2.279
ITGAM
205786_s_at integrin, alpha M (complement component 3 receptor 3 subunit) 2.866
205147_x_at neutrophil cytosolic factor 4, 40kDa NCF4 2.145
204118_at CD48 molecule CD48 2.938
211795_s_at FYN binding protein (FYB-120/130) FYB 2.956
208018_s_at hemopoietic cell kinase HCK 2.826
204959_at myeloid cell nuclear differentiation antigen MNDA 3.943
209906_at complement component 3a receptor 1 C3AR1 2.524
204122_at TYRO protein tyrosine kinase binding protein TYROBP 2.935
FCER1G
204232_at Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 3.263
210895_s_at CD86 molecule CD86 3.478
204912_at interleukin 10 receptor, alpha IL10RA 3.047
207238_s_at protein tyrosine phosphatase, receptor type, C PTPRC 3.799
212588_at protein tyrosine phosphatase, receptor type, C PTPRC 4.239
221698_s_at C-type lectin domain family 7, member A CLEC7A 2.654
CSF1R viral
203104_at colony stimulating factor 1 receptor, formerly McDonough feline sarcoma 2.772 (v-fms) oncoge
201743_at CD14 molecule CD14 3.538
221581_s_at linker for activation of T cells family, member 2 LAT2 2.253
201859_at serglycin SRGN 2.583
204103_at chemokine (C-C motif) ligand 4 CCL4 3.307
CYBB
203923_s_at cytochrome b-245, beta polypeptide (chronic granulomatous disease) 3.485
212587_s_at protein tyrosine phosphatase, receptor type, C PTPRC 3.979
203508_at tumor necrosis factor receptor superfamily, member 1B TNFRSF1B 2.154
201422_at interferon, gamma-inducible protein 30 IFI30 2.841
CASP1
211368_s_at caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
3.681
203547_at CD4 molecule CD4 1.946
RAC2
207419_s_at ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
2.294
SPI1
205312_at spleen focus forming virus (SFFV) proviral integration oncogene spi1 1.507
NCF1 1)
204961_s_at neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 2.085
203665_at heme oxygenase (decycling) 1 HMOX1 2.160
216598_s_at chemokine (C-C motif) ligand 2 CCL2 3.007
214677_x_at immunoglobulin lambda joining 3 IGLJ3 4.977
209138_x_at immunoglobulin lambda locus IGL@ 4.451
215121_x_at immunoglobulin lambda locus IGL@ 3.832
221651_x_at major histocompatibility complex, class I, C HLA-C 4.027
221671_x_at major histocompatibility complex, class I, C HLA-C 4.022
211430_s_at immunoglobulin heavy constant gamma 3 (G3m marker) IGHG3 6.089
217022_s_at immunoglobulin heavy constant alpha 1 IGHA1 6.157
205114_s_at chemokine (C-C motif) ligand 3 CCL3 2.777
202087_s_at cathepsin L1 CTSL1 1.584
213418_at heat shock 70kDa protein 6 (HSP70B') HSPA6 2.120
NFKB1
209239_at nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)1.765
203382_s_at apolipoprotein E APOE 2.324
IFIT2
217502_at interferon-induced protein with tetratricopeptide repeats 2 2.107
209417_s_at interferon-induced protein 35 IFI35 2.150
signal transducer and
AFFX-HUMISGF3A/M97935_MB_at activator of transcription 1, 91kDa STAT1 2.225
214453_s_at interferon-induced protein 44 IFI44 1.941
TAP2
204770_at transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.820
217757_at alpha-2-macroglobulin A2M 1.852
10
202687_s_at tumor necrosis factor (ligand) superfamily, memberTNFSF10 2.973
205729_at oncostatin M receptor OSMR 2.860
STAT3
208992_s_at signal transducer and activator of transcription 3 (acute-phase response factor)
1.706
208965_s_at interferon, gamma-inducible protein 16 IFI16 2.252
208451_s_at complement component 4A (Rodgers blood group) C4A 2.154
NR3C1
211671_s_at nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)1.970
201648_at Janus kinase 1 (a protein tyrosine kinase) JAK1 1.375
211822_s_at NLR family, pyrin domain containing 1 NLRP1 1.200
ITGAV
202351_at integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 2.014
203275_at interferon regulatory factor 2 IRF2 1.690
211744_s_at CD58 molecule CD58 1.992
205842_s_at Janus kinase 2 (a protein tyrosine kinase) JAK2 1.582
212501_at CCAAT/enhancer binding protein (C/EBP), beta CEBPB 1.571
206359_at suppressor of cytokine signaling 3 SOCS3 1.946
201473_at jun B proto-oncogene JUNB 2.331
209189_at v-fos FBJ murine osteosarcoma viral oncogene homolog FOS 3.367
202768_at FBJ murine osteosarcoma viral oncogene homolog B FOSB 2.530
NFKB2
207535_s_at nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
1.615
204725_s_at NCK adaptor protein 1 NCK1 1.588
REL
206036_s_at v-rel reticuloendotheliosis viral oncogene homolog (avian) 1.458
1
221491_x_at major histocompatibility complex, class II, DR beta HLA-DRB1 1.631
PLA2G7
206214_at phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
1.446
211892_s_at prostaglandin I2 (prostacyclin) synthase PTGIS 1.185
PLA2G2A
203649_s_at phospholipase A2, group IIA (platelets, synovial fluid) 1.968
LOC390569
212999_x_at similar to amyloid beta A4 precursor protein-binding, family A, member 2 1.777
209321_s_at adenylate cyclase 3 ADCY3 1.430
218172_s_at Der1-like domain family, member 1 DERL1 1.285
IL6ST
211000_s_at interleukin 6 signal transducer (gp130, oncostatin M receptor) 1.650
203265_s_at mitogen-activated protein kinase kinase 4 MAP2K4 1.180
212777_at son of sevenless homolog 1 (Drosophila) SOS1 1.272
211578_s_at ribosomal protein S6 kinase, 70kDa, polypeptide 1 RPS6KB1 1.318
P.Value
0.0312
0.0153
0.0099
0.0332
0.0130
0.0418
0.0404
0.0207
0.0207
0.0452
0.0181
0.0410
0.0268
0.0100
0.0000
0.0020
0.0000
0.0000
0.0000
0.0451
0.0003
0.0013
0.0000
0.0000
0.0000
0.0068
0.0035
0.0000
0.0000
0.0000
0.0000
0.0000
0.0001
0.0000
0.0000
0.0000
0.0000
0.0301
0.0001
0.0000
0.0000
0.0000
0.0000
0.0000
0.0000
0.0000
0.0000
0.0000
0.0000
0.0000
0.0000
0.0005
0.0005
0.0000
0.0000
0.0000
0.0000
0.0016
0.0000
0.0000
0.0006
0.0000
0.0000
0.0036
0.0000
0.0010
0.0000
0.0007
0.0005
0.0004
0.0003
0.0001
0.0005
0.0172
0.0485
0.0074
0.0066
0.0454
P.Value
0.038
0.010
0.009
0.013
0.035
0.024
0.021
0.027
0.043
0.004
0.000
0.002
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.001
0.000
0.000
0.000
0.007
0.003
0.049
0.025
0.001
0.019
0.000
0.009
0.004
0.004
0.000
0.003
0.000
0.000
0.000
0.005
0.008
0.010
0.000
0.000
0.000
0.000
0.045
0.000
0.010
0.000
0.040
0.017
0.031
0.026
P.Value
0.013
0.040
0.044
0.026
0.013
0.044
0.000
0.003
0.016
0.014
0.021
0.021
0.040
0.046
0.000
0.033
0.000
0.010
0.010
0.025
0.049
0.000
0.000
0.003
0.007
0.005
0.000
0.008
0.045
0.022
0.000
0.000
0.000
0.015
0.045
0.000
0.000
0.027
0.001
0.025
0.000
0.001
0.000
0.000
0.000
0.004
0.001
0.000
0.000
0.000
0.004
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.015
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.001
0.000
0.001
0.013
0.026
0.001
0.030
P.Value
0.024
0.022
0.008
0.023
0.041
0.048
0.038
0.027
0.000
0.026
0.017
0.013
0.009
0.010
0.001
0.002
0.024
0.000
0.000
0.027
0.000
0.010
0.001
0.015
0.002
0.042
0.021
0.041
0.000
0.049
0.025
0.033
0.001
0.045
0.002
0.000
0.017
0.000
0.000
0.009
0.004
0.000
0.000
0.000
0.019
0.000
0.001
0.000
0.000
0.044
0.003
0.000
0.001
0.000
0.000
0.007
0.000
0.000
0.000
0.000
0.000
0.000
0.015
0.008
0.000
0.045
0.000
0.043
0.000
0.044
0.003
0.001
0.007
0.031
0.000
0.013
0.031
0.000
0.000
0.009
0.001
0.024
0.003
0.000
0.000
0.000
0.008
0.000
0.000
0.000
0.001
0.000
0.002
0.000
0.000
0.000
0.000
0.000
0.000
0.001
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.015
0.000
0.000
0.000
0.000
0.000
0.002
0.001
0.000
0.003
0.000
0.007
0.003
0.006
0.007
0.006
0.000
0.001
0.005
0.000
0.000
0.000
0.000
0.000
0.000
0.002
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.001
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.001
0.000
0.000
0.000
0.000
0.000
0.000
0.001
0.000
0.000
0.007
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.001
0.000
0.000
0.001
0.022
0.049
0.010
0.002
0.006
0.004
0.005
0.010
0.040
0.021
0.014