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gonorrhea
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Gonorrhea



Sexually Transmitted Disease

Surveillance 2007



Division of STD Prevention

Gonorrhea — Rates: United States, 1941–2007 and the Healthy People 2010 target







Rate (per 100,000 population)

500

Gonorrhea

2010 Target

400





300





200





100





0



1941 46 51 56 61 66 71 76 81 86 91 96 2001 06







Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000

population.

Gonorrhea — Rates: Total and by sex: United States, 1988–2007 and the

Healthy People 2010 target







Rate (per 100,000 population)

400

Male

Female

320 Total

2010 Target



240





160





80





0



1988 90 92 94 96 98 2000 02 04 06







Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000

population.

Gonorrhea — Rates by region: United States, 1998–2007 and the

Healthy People 2010 target







Rate (per 100,000 population)

300

West

Midwest

240 Northeast

South

2010 Target

180





120





60





0



1998 99 2000 01 02 03 04 05 06 07







Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000

population.

Gonorrhea — Rates by state: United States and outlying areas, 2007





57.1

VT 10.3

12.9 18.2 8.9 NH 10.5

33.4 66.9

MA 41.9

18.3 121.5 RI 37.7

33.4 91.7

15.7 153.4

CT 66.4

64.7

NJ 69.6

102.1

94.4 81.1 DE 151.5

183.5

32.2 162.2139.2 MD 120.5

85.8 71.0 51.1 82.0 DC 408.1

82.6 169.0 82.0

Guam 82.4

158.4

188.2 Rate per 100,000

82.1 134.9

91.9 148.3 239.0 population

190.5

285.7 236.7 100 (n= 21)



P uerto Rico 8.2



V irgin Is. 63.5









Note: The total rate of gonorrhea for the United States and outlying areas

(Guam, Puerto Rico and Virgin Islands) was 117.4 per 100,000 population.

The Healthy People 2010 target is 19.0 cases per 100,000 population.

Gonorrhea — Rates by county: United States, 2007









Rate per 100,000

population

100.0 (n= 736)









Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000 population.

Gonorrhea — Age- and sex-specific rates: United States, 2007







Men Rate (per 100,000 population) Women



750 600 450 300 150 0 Age 0 150 300 450 600 750



5.9 10-14 33.1

286.0 15-19 647.9

450.1 20-24 614.5

305.1 25-29 287.1

181.5 30-34 125.2

119.5 35-39 60.5

86.6 40-44 30.8

50.2 45-54 12.1

17.7 55-64 3.0

4.0 65+ 0.4

113.9 Total 123.8

Gonorrhea — Age-specific rates among women 15 to 44 years of age:

United States, 1998–2007





Rate (per 100,000 population)

1,000

15-19 20-24

25-29 30-34

35-39 40-44

800





600





400





200





0



1998 99 2000 01 02 03 04 05 06 07

Gonorrhea — Age-specific rates among men 15 to 44 years of age:

United States, 1998–2007





Rate (per 100,000 population)

750

15-19 20-24

25-29 30-34

35-39 40-44

600





450





300





150





0



1998 99 2000 01 02 03 04 05 06 07

Gonorrhea — Rates by race/ethnicity: United States, 1998–2007







Rate (per 100,000 population)

900





720





540 American Indian/AK Native

Asian/Pacific Islander

Black

Hispanic

360 White







180





0



1998 99 2000 01 02 03 04 05 06 07

Gonorrhea — Cases by reporting source and sex: United States, 1998–2007







Cases (in thousands)

200

non-STD Clinic Male

non-STD Clinic Female

STD Clinic Male

160 STD Clinic Female





120





80





40





0



1998 99 2000 01 02 03 04 05 06 07

Gonorrhea — Positivity among 15- to 24-year-old women tested in family planning

clinics by state: United States and outlying areas, 2007



0.5

VT 0.1

0.8 0.1 NH 0.1

0.5

MA

0.2 4.9 RI

0.5

0.2 1.7

CT 0.6

0.6

NJ 1.4

0.9

0.8 0.9 DE 1.1

1.8

1.1 1.6 1.6 MD

1.1 0.6 1.2 DC

0.9 1.3 0.7

1.5

0.9

0.8 0.8 Positivity (%)

0.9 2.0 2.4

3.8 2.7

3.3 See* (n= 8)

2.8

0.4 2.2 =2.0 (n= 9)

P uerto Rico 0.1



V irgin Is. 3.6



*States/areas not meeting minimum inclusion criteria.

Note: Includes states and outlying areas that reported positivity data on at least 500

women aged 15-24 years screened during 2007.



SOURCE: Gonorrhea Prevalence Monitoring Project (Regional Infertility Prevention Projects); Office of Population Affairs; Loc al and

State STD Control Programs; Centers for Disease Control and Prevention

Gonococcal Isolate Surveillance Project (GISP) — Prevalence of ciprofloxacin

resistant Neisseria gonorrhoeae by GISP site, 2004-2007





SEA



POR

MIN

DTR

NYC

CHI

CLE

SFO

DEN CIN BAL PHI

LVG KCY

LAX GRB

LBC RIC

QR N G P revalence

ORA ALB OKC

PHX 50%

ATL

BHM

DAL

25%





SDG

0%

HON NOR

' ' '

' 0 40 50 60 7

TRP



MIA





Note: Not all clinics participated in GISP for the last 4 years. Sites include: ALB=Albuquerque, NM; ATL=Atlanta, GA;

BAL=Baltimore, MD; BHM=Birmingham, AL; CHI=Chicago, IL; CIN=Cincinnati, OH; CLE=Cleveland, OH;

DAL=Dallas, TX; DEN=Denver, CO; DTR=Detroit, MI; GRB=Greensboro, NC; HON=Honolulu, HI; KCY=Kansas

City, MO; LAX=Los Angeles, CA; LBC=Long Beach, CA; LVG=Las Vegas, NV; MIA=Miami, FL;

MIN=Minneapolis, MN; NOR=New Orleans, LA; NYC=New York City, NY; OKC=Oklahoma City, OK;

ORA=Orange County, CA; PHI=Philadelphia, PA; PHX=Phoenix, AZ; POR=Portland, OR; SDG=San Diego, CA;

SEA=Seattle, WA; SFO=San Francisco, CA; and TRP=Tripler Army Medical Center, HI

Gonococcal Isolate Surveillance Project (GISP) — Penicillin, tetracycline, and

ciprofloxacin resistance among GISP isolates, 2007









Note: PenR=penicillinase producing N. gonorrhoeae and chromosomally mediated

penicillin-resistant N. gonorrhoeae; TetR=chromosomally and plasmid mediated

tetracycline-resistant N. gonorrhoeae; QRNG=ciprofloxacin resistant N. gonorrhoeae.

Gonococcal Isolate Surveillance Project (GISP) — Percent of Neisseria

gonorrhoeae isolates with resistance or intermediate resistance to ciprofloxacin,

1990–2007





Percent

16



Resistance

12 Intermediate resistance







8







4







0

1990 91 92 93 94 95 96 97 98 99 2000 01 02 03 04 05 06 07





Note: Resistant isolates have ciprofloxacin MICs ≥ 1 µg/ml. Isolates with

intermediate resistance have ciprofloxacin MICs of 0.125 - 0.5 µg/ml.

Susceptibility to ciprofloxacin was first measured in GISP in 1990.

Gonococcal Isolate Surveillance Project (GISP) — Percent of Neisseria

gonorrhoeae isolates with resistance to ciprofloxacin by sexual behavior,

2001–2007





Percent

40



Heterosexual men

32 Men who have sex with men (MSM)



24





16





8





0

2001 2002 2003 2004 2005 2006 2007


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