JNC1213suppmatt

expression in rat prefrontal cortex in response to clozapine treatment

Atlas Rat 1.2 Array (Cat. #7854-1) RATIO RATIO RATIO in situ hybridization

Gene ID array ID Genbank Swissprot gene name cloz 1h cloz 6h cloz 24h done reg.

R234 A01a L34067 P35053 glypican 1 1.393 1.030 0.601 no

R077 A01b D26439 Q63493 CD1D antigen 0.848 1.112 0.980 no

R246 A01c 0.929 1.022 leukocyte-common antigen/T200 glycoprotein) also RT7

M10072 P04157 Protein tyrosine phosphatase, receptor-type, c polypeptide (antigen Cd45, 0.879 no

R024 A01d AF017437 O35294 integrin-associated protein 0.862 0.931 0.892 no

RG068 A01e 0.870 0.870 0.977 no

J04793 P23562 Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3)

RG076 A01f K03242 P06907 Myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) 1.000 1.000 1.000 no

RG146 A01g M21730 P14668 Annexin V 1.075 0.864 0.991 no

RG396 A01h X76489 P40241 CD9 antigen (p24) 1.146 1.101 1.389 no

RG481 A01i U00995 Q63016 tumor-associated protein 1 1.081 1.185 0.787 no

R464 A01j U33553 Q62831 chondroitin sulfate proteoglycan 5 1.287 0.915 1.019 no

R215 A01k L19931 Q63488 solute carrier family 20, member 2 1.176 1.111 1.146 no

R438 A01l U12309 P49134 Integrin, beta 1 0.897 1.106 0.729 no

R496 A01m U60096 Q64632 Integrin, beta 4 1.055 1.271 1.000 no

RG007 A01n receptor)

AF072411 Q07969 CD36 antigen (collagen type I receptor, thrombospondin1.223 1.353 0.998 no

RG299 A02a P33671 P97614

U52825 syndecan 3 0.827 1.076 0.852 no

R331 A02b P Cell 0.854 0.935 0.871 no

M61875 26051 Q99021 surface glycoprotein CD44 (hyaluronate binding protein)

R221 A02c L25527 P98105 Selectin, endothelial cell 1.059 1.000 1.000 no

R218 A02d L23088 P98106 Selectin, platelet 1.443 0.960 1.000 no

R038 A02e D10831 P30836 selectin, lymphocyte 1.453 0.873 0.922 no

R389 A02f M92848 P16573 carcinoembryonic antigen-related cell adhesion molecule 0.803 0.746 1.086 no

R071 A02g D25290 P55280 Cadherin 6 (K-cadherin) 0.665 0.970 1.314 no

R615 A02h D83349 Q63561 cadherin 22 1.053 1.038 0.963 no

RG341 A02i X52140 P18614 Integrin, alpha 1 0.864 1.121 0.957 no

RG403 A02j X78997 P55281 cadherin 17 0.936 0.907 0.949 no

R361 A02k M84488 P29534 Vascular cell adhesion molecule 1 1.511 1.460 1.258 no

R428 A02l Q Protein tyrosine phosphatase, receptor-type, zeta polypeptide 1.014 1.096 no

U09357 62656 Q62621 0.911

R097 A02m D38492 Q63198 contactin 1 1.086 1.203 1.130 no

R435 A02n cell adhesion 1.095 no

U11031 Q62682 Plasmacytoma-associated neuronal glycoprotein (neural0.986 0.932molecule BIG-1)

R003 A03a AB004276 O08963 protocadherin 4 0.967 0.848 0.790 no

R196 A03b L08447 T-cell receptor CD3, subunit zeta 1.000 1.000 1.000 no

R033 A03c D10728 P51882 Lymphocyte antigen CD5 0.850 0.752 0.761 no

R121 A03d D55648 T-cell receptor, gamma cluster 1.087 1.049 1.000 no

R019 A03e (B7-1)

AF010465 O35187 Cd80 a rat homolog of the human CD28/CTLA - 4 ligand1.639 1.024 1.030 no

RG175 A03f M57276 P24485 Leukocyte antigen (Ox-44) 1.359 1.192 0.733 no

RG452 A03g M15768 P05540 CD4 antigen (p55) 1.450 0.871 1.073 no

RG478 A03h S79711 Q64159 CD3, gamma chain 1.382 1.306 0.714 no

RG504 A03i X04310 P05541 CD8 antigen, beta-chain 1.066 1.418 0.767 no

R115 A03j D49955 Q63072 bone marrow stromal cell antigen 1 1.028 1.025 0.968 no

R165 A03k 1.196 1.126 1.000 no

U70476 P70608 Solute carrier family 7 member A1 (amino acid transporter cationic 1)

R462 A03l U31367 Q64349 MAL protein gene 1.011 1.233 0.984 no

R072 A03m D26112 Q63199 Tumor necrosis factor receptor superfamily, member 6 1.000 1.168 1.000 no

R102 A03n D42117 P97525 Tumor necrosis factor superfamily, member CD30 1.000 1.000 1.000 no

R333 A04a M63122 P22934 Tumor necrosis factor receptor superfamily, member 1a 0.848 0.842 0.977 no

R388 A04b M92340 P40190 Interleukin 6 signal transducer 1.173 0.966 1.708 no

R322 A04c M58587 P22273 Interleukin 6 receptor 0.841 0.841 0.839 no

R313 A04d M55049 P26897 Interleukin 2 receptor, alpha chain 1.490 1.000 1.247 no

R015 A04e O35771 P49616

AF007789 Plasminogen activator, urokinase receptor 1.488 0.907 1.776 no

R481 A04f U49062 Q07490 CD24 antigen 1.246 1.727 1.942 no

RG354 A04g X55288 P31042 CD28 antigen 1.039 1.021 0.931 no

RG121 A04h L33413 Q63495 advanced glycosylation end product-specific receptor 0.795 1.169 1.457 no

RG322 CD2 0.579 0.667 no

A04i X05111 P08921 OX-45 surface antigen, homolog to human T lymphocyte0.989 antigen

R522 receptor)-like 0.793

A04j U76205 P97943 CD36 antigen (collagen type I receptor, thrombospondin0.780 0.8741 (scavanger no receptor class B type 1)

R319 A04k M58040 Q99376 transferrin receptor 0.913 0.924 1.002 no

R626 A04l L14851 Q07280 neurexin 3 0.953 0.948 0.901 no

R345 A04m M69139 P25094 Peripheral myelin protein 1.000 1.353 1.126 no

R085 0.884 1.005 1.115 no

A04n D30795 Q64244 CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase)

RG240 A05a S73583 P50123 aminopeptidase A 1.192 1.000 1.000 no

R490 A05b U56936 Q62983 NK lymphocyte receptor; NKR-P1B 0.958 0.958 0.946 no

R010 A05c AF003008 O09015 Max interacting protein 1 1.165 1.495 1.236 yes no

R450 A05d U18913 P51145 Fos like antigen 2 1.570 1.000 1.000 no

R563 A05e X54686 P24898 jun B proto-oncogene 2.269 1.245 0.874 no

R076 A05f D26307 P52909 Jun D proto-oncogene 1.526 0.863 1.003 no

R054 A05g D14447 P52164 Max 1.168 1.823 1.594 yes no

R472 A05h U38938 Q62870 RATF2 0.568 0.990 0.537 no

R576 1.593 1.378 1.171 no

A05i X63594 Q63746 Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha

R592 A05j X91810 P52631 Signal transducer and activator of transcription 3 0.991 1.797 1.074 yes no

R224 A05k L26267 Q63369 nuclear factor kappa B p105 subunit 1.577 1.240 1.000 no

R557 A05l X14788 P15337 cAMP response element binding protein 1 1.000 1.282 1.000 no

R296 A05m M34253 P23570 Interferon regulatory factor 1 1.000 1.201 1.046 no

RG258 A05n U09229 P53565 cut (Drosophila)-like 1 1.000 1.000 1.000 no

RG280 A06a U23769 P52944 PDZ and LIM domain 1 (elfin) 0.707 0.744 1.009 no

RG404 A06b X81193 P50463 cysteine-rich protein 3 1.000 1.000 1.360 no

RG423 A06c Z17223 P39020 mesenchyme homeobox 2 1.264 0.929 0.902 no

R480 A06d U48248 Q62921 protein kinase C-binding protein Beta15 0.873 1.118 1.465 no

R235 A06e L35572 P50459 LIM homeobox protein 5 0.608 0.724 0.692 no

R461 A06f U30186 Q62804 DNA-damage inducible transcript 3 0.989 0.849 1.519 no

R039 1.314 1.516 1.892 no

A06g D10862 P41135 Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation)

R040 0.996 1.229 1.729 yes yes

A06h D10863 P41137 Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

R041 1.137 1.249 1.741 no

A06i D10864 P41138 Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

R229 A06j L29259 Q63182 elongation factor SIII p15 subunit 0.884 0.987 1.085 no

R594 A06k X94351 Q63117 CDC-like kinase 3 1.201 0.900 0.975 no

R393 A06l M94064 Q00566 methyl CpG binding protein 2 0.669 0.669 0.785 no

R578 A06m X64589 P30277 Cyclin B1 0.767 0.942 0.779 no

R049 A06n D14013 P39947 cyclin C 0.544 0.563 0.561 no

R050 A07a D14014 P39948 Cyclin D1 1.429 0.753 1.053 no

R057 A07b D16308 Q04827 G1/S-specific cyclin D2 (CCND2); vin-1 proto-oncogene 1.364 1.326 1.911 no

R058 A07c D16309 P48961 Cyclin D3 1.679 1.187 1.079 no

R051 A07d D14015 P39949 Cyclin E1 1.145 0.771 0.656 no

R585 A07e X70871 P39950 Cyclin G1 0.966 0.882 1.040 no

R080 Q cyclin-dependent kinase 2 alpha (CDK2-alpha) + cyclin-dependent kinase 2-beta (CDK2-beta)

A07f D28753 63699 Q63700 0.912 0.665 0.662 no

R590 0.859 0.759 kinase)

A07g X83579 P51952 cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating0.768 no

R100 A07h D38560 P97874 cyclin G-associated kinase 0.781 0.639 0.557 no

R220 1.156 0.916 1.139 no

A07i L24388 P46892 p58/GTA; galactosyltransferase associated protein kinase (cdc2-related protein kinase)

R134 A07j D83792 O35792 Cyclin-dependent kinase inhibitor 1B, (p27, Kip1) 1.070 1.092 0.941 no

R409 A07k S79760 P55272 Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.616 1.000 1.304 no

R056 A07l D16237 P48966 cell division cycle 25B 1.185 1.309 1.221 no

R529 A07m U82591 O35820 putative c-Myc-responsive 0.499 0.814 0.351 no

R418 A07n U05341 Q62623 cell cycle protein p55CDC 1.107 1.454 1.000 no

R600 A08a Y00047 P04961 Proliferating cell nuclear antigen 1.103 1.684 1.404 no

R330 A08b M61219 P24142 Prohibitin 1.260 1.126 1.060 no

R232 A08c L32591 P48317 DNA-damage-inducible transcript 1 1.178 1.609 1.000 no

RG339 A08d X16956 P07151 Beta-2-microglobulin 0.880 0.958 1.032 no

R658 A08e M20035 P06302 prothymosin alpha 1.094 2.402 1.539 yes no

R052 A08f D14051 Q06518 Nitric oxide synthase 2, inducible 0.791 0.671 0.688 no

R471 A08g U38376 P50393 phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.800 0.800 0.800 no

R106 A08h P Cathepsin E

D45187 16228 Q63701 1.071 0.795 0.954 no

RG344 A08i X52711 P18588 interferon-induced GTP-binding, mx1 1.001 0.779 0.992 no

RG345 A08j (also 1.000 1.150 no

X52712 P18589 Myxovirus (influenza) resistance, homolog of murine Mx 1.371 interferon-inducible protein IFI78)

RG262 A08k U11760 P46462 valosin-containing protein 1.141 1.075 1.269 no

R253 A08l M14050 P06761 Heat shock 70kD protein 5 1.190 1.129 1.402 no

R069 A08m D23676 P35231 regenerating islet-derived 3 alpha 1.007 1.118 1.000 no

RG361 A08n X57523 P36370 Transporter 1, ABC (ATP binding cassette) 0.965 0.750 0.592 no

RG394 A09a X75305 P36372 Transporter 2, ABC (ATP binding cassette) 1.251 1.337 0.878 no

R323 A09b M58590 P14272 Plasma kallikrein 1.000 1.112 1.000 no

R670 A09c M34097 P18291 natural killer (NK) cell protease 1 (RNKP-1) 1.000 1.000 1.000 no

R702 A09d U57062 Q63636 granzyme C 1.000 1.074 1.000 no

R342 A09e M65253 P07152 matrix metalloproteinase 10 1.000 1.000 1.000 no

R589 A09f X83537 Q10739 matrix metalloproteinase 14, membrane-inserted 0.511 0.865 0.307 no

R034 A09g D10754 P28073 proteasome (prosome, macropain) subunit, beta type 6 1.117 0.778 0.810 no

R037 A09h D10757 P28077 Low molecular mass polypeptide 2 0.514 0.677 0.524 no

RG014 A09i (low 0.745 0.759 no

D10729 P28064 Proteasome (prosome, macropain) subunit, beta type, 8 0.745 molecular mass polypeptide 7)

R244 A09j M00001 P04639 Apolipoprotein A-I 1.000 1.013 1.000 no

R245 A09k M00002 P02651 Apolipoprotein A-IV 1.267 1.000 1.000 no

RG231 A09l 1.022 1.047 1.000 no

S46785 P35859 insulin-like growth factor binding protein, acid labile subunit

RG389 A09m X74806 P41244 VEGP2 gene 1.000 1.303 1.000 no

RG517 A09n X55572 P23593 Apolipoprotein D 1.129 1.039 0.745 no

R312 A10a M38759 Q63029 Histidine decarboxylase 1.000 1.083 1.000 no

R279 A10b M27156 P15399 probasin 1.000 1.071 1.000 no

R553 A10c X13058 P10361 Tumor protein p53 (Li-Fraumeni syndrome) 1.204 1.574 1.000 no

R493 A10d 1.000 1.376

U58857 P70564 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 1.000 no

R444 A10e Q von

U14746 64259 Q64197 Hippel-Lindau syndrome 1.042 1.257 0.782 no

R583 A10f X69716 P49952 Wilms tumor 1 0.423 0.606 0.435 no

R549 A10g X06769 P12841 c-fos proto-oncogene 0.426 0.370 0.353 no

R601 A10h Y00396 P09416 Avian myelocytomatosis viral (v-myc) oncogene homolog 0.369 0.487 0.294 no

R718 A10i X63281 Q63379 N-myc proto-oncogene protein 0.835 0.833 1.081 no

R560 A10j X17163 P17325 Avian sarcoma virus 17 (v-jun) oncogene homolog 2.245 2.034 1.833 no

R669 A10k M29069 P23999 Myc-like oncogene, s-myc protein 1.000 1.000 1.196 no

R216 A10l (tumor 1.000 1.494

L20681 P41156 Ets avian erythroblastosis virus E2 oncogene homolog 11.082 progression locus 1)no

RG032 A10m D17512 P36201 cysteine-rich protein 2 1.487 0.763 1.119 no

R070 A10n D25233 Q63527 Retinoblastoma 1 (including osteosarcoma) 1.778 1.000 1.000 no

R264 A11a M19651 P10158 Fos-like antigen 1 1.000 1.000 1.630 no

R240 A11b L41275 Q64315 cyclin-dependent kinase inhibitor 1A (P21) 1.000 1.000 1.719 no

RG113 A11c L26268 Q63073 B-cell translocation gene 1, anti-proliferative 1.000 1.000 1.998 no

R084 A11d D30041 P47197 Murine thymoma viral (v-akt) oncogene homolog 2 1.825 1.207 1.740 no

R045 A11e 1.292 diphosphate kinase)

D13374 Q05982 expressed in non-metastatic cells 1, protein (NM23A) (nucleoside1.073 1.557 no

R386 A11f M91597 P19804 nucleoside diphosphate kinase 1.207 0.872 1.309 no

R512 A11g U68725 Q63155 Deleted in colcorectal cancer (rat homolog) 0.157 0.351 0.153 no

R513 A11h U68726 P97603 neogenin 0.103 0.306 0.069 no

R042 A11i D12524 Q63116 c-kit receptor tyrosine kinase 1.341 1.346 1.046 no

R612 A11j D12498 P13109 Fibroblast growth factor receptor 1 1.299 1.275 1.557 no

R547 A11k 1.098 1.484 1.000 no

X03362 P06494 Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog)

R460 A11l Q avian

U29339 62799 Q62955 erythroblastosis oncogene B 3 1.418 1.323 1.182 no

RG206 A11m M85214 P35739 trk precursor 1.249 1.247 1.000 no

R607 A11n Z14117 Q05028 Platelet-derived growth factor 3.421 2.176 2.376 no

R285 A12a P Transforming growth factor, alpha

M31076 01134 Q63749 1.000 1.000 1.000 no

R104 A12b D44481 Q63768 v-crk avian sarcoma virus CT10 oncogene homolog 0.890 2.228 0.997 no

R551 A12c X06942 P14056 A-raf 1.094 2.012 2.196 no

R211 A12d L15619 casein kinase II beta subunit

P13862 P07312 1.816 0.872 1.176 no

R577 A12e X63675 P26794 Pim-1 oncogene 2.123 1.000 1.006 no

R648 1.253

A12f M15427 P11345 Murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV) 0.792 0.914 no

R717 A12g X57018 Q63206 FGR 0.553 0.380 0.401 no

R700 A12h U35365 Q62844 Fyn proto-oncogene 0.722 0.842 0.826 no

R083 A12i D30040 P47196 Murine thymoma viral (v-akt) oncogene homolog 1 1.340 0.881 0.978 no

RG348 A12j X52952 P00539 Moloney murine sarcoma viral (v-mos) oncogene homolog 1.000 1.000 1.000 no

R647 A12k M13011 P20171 H-ras proto-oncogene; transforming protein p21 1.136 1.278 1.149 no

R719 A12l X68394 Q04970 Neuroblastoma RAS viral (v-ras) oncogene homolog 1.000 1.000 1.000 no

R694 1

A12m U09793 P46203 Kirsten rat sarcoma viral oncogene homologue 2 (active) .283 2.086 2.393 no

RG199 1.453 1.881

A12n M83675 P35280 mel transforming oncogene (derived from cell line NK14)- RAB8 homolog 1.311 no

R206 A13a L13151 P50904 RAS p21 protein activator 0.620 0.659 0.673 no

R093 A13b D37880 P55146 Bruton agammaglobulinemia tyrosine kinase 1.380 1.147 1.163 no

R299 A13c M35105 Q63131 Rat heart - derived c - ros - 1 proto - oncogene 1.000 1.000 1.431 no

R162 A13d J03823 P12526 MAS1 oncogene 0.741 0.721 1.512 no

R499 A13e U61772 Q63648 Neurofibromatosis 2 0.536 0.727 1.294 no

R593 A13f X93591 P54275 mismatch repair protein 1.281 0.596 1.552 no

R101 A13g D38629 P70478 Adenomatosis polyposis coli 0.975 0.755 0.826 no

R120 A13h D55627 O55081 Retinoblastoma-related gene 1.044 0.706 1.271 no

R107 A13i D45201 P97526 Neurofibromatosis type 1 1.927 0.674 3.234 no

R364 A13j M86389 P42930 heat shock 27kD protein 1 1.044 1.584 1.044 no

R405 1.826

A13k S45392 P34058 heat shock 90-kDa protein beta (HSP90-beta); HSP84; HSPCB 2.048 3.196 no

R564 A13l X54793 P19226 heat shock protein 60 (liver) 1.250 1.642 2.181 no

R609 A13m Z27118 Q63718 Heat shock protein 70-1 1.380 1.000 1.000 no

R432 A13n U09870 Q62667 major vault protein 1.000 1.000 1.000 no

R596 1.000 1.826 resistance-associated protein)

A14a X96394 Q63346 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (multiple drug1.000 no

R421 A14b U06099 P35704 peroxiredoxin 2 1.130 0.887 0.638 no

R172 A14c K01931 P00502 Glutathione-S-transferase, alpha type (Yc?) 1.000 1.354 1.000 no

R158 A14d J03752 P08011 microsomal glutathione S-transferase 1 1.134 1.185 1.216 no

R145 A14e J02592 P08010 Glutathione-S-transferase, mu type 2 (Yb2) 0.873 1.311 0.689 no

R581 A14f X67654 Q01579 Glutathione S-transferase 1 (theta) 0.712 0.874 0.703 no

R546 A14g X02904 P04906 glutathione S-transferase, pi 1 1.232 0.759 1.270 no

R242 A14h L46791 carboxylesterase 3

P16303 Q64574 0.924 0.662 0.689 no

RG246 A14i S83436 glutahione S-transferase subunit 13

P24473 O09034 1.176 0.862 0.927 no

RG376 A14j X62404 P30710 glutathione peroxidase 5 1.361 1.000 1.000 no

RG405 A14k X82679 P36970 glutathione peroxidase 4 1.527 0.632 1.066 no

RG429 A14l D10026 glutathione S-transferase, theta 2

P30713 P36971 2.611 0.863 3.581 no

RG524 A14m X62660 P14942 glutathione transferase, subunit 8 0.954 1.520 1.802 no

R249 A14n M12516 P00388 P450 (cytochrome) oxidoreductase 1.193 0.953 0.656 no

R430 B01a U09540 Q64678 Cytochrome P450 1b1 1.000 1.353 1.000 no

R545 1.000 1.000 (C6,

B01b X00469 P00185 Cytochrome P450, subfamily I (aromatic compound-inducible), member A11.000form c) no

R619 B01c J05460 Cytochrom P450 (cholesterol hydroxylase 7 alpha)

P18125 P51543 1.134 1.000 1.000 no

RG051 B01d J02627 P05182 Cytochrome P450, subfamily 2e1 (ethanol-inducible) 1.000 1.068 1.000 no

RG074 B01e K02422 Cytochrome P450, subfamily I (aromatic compound-inducible), member A21.000 form d)

P04799 Q64588 1.311 1.000 (Q42, no

RG158 B01f M29853 P15129 Cytochrome P450, subfamily IVB, polypeptide 1 1.605 1.541 1.206 no

RG271 Q Cytochrom P450 Lanosterol 14 alpha-demethylase

B01g U17697 64654 Q64549 1.473 1.349 1.568 no

R602 B01h Y00404 P07632 Superoxide dismutase 1, soluble 1.444 1.072 1.981 no

R030 B01i D00680 P23764 plasma glutathione peroxidase precursor 1.217 1.491 0.722 no

R005 1.286

B01j AB004559 O35956 solute carrier family 22 (organic anion transporter), member 6 1.203 1.000 no

R614 B01k D79981 P70502 kidney specific organic anion transporter 1.269 1.539 1.065 no

R130 B01l D83044 P70485 solute carrier family 22, member 2 1.245 1.000 1.000 no

R523 B01m U76379 Q63089 Organic cation transporter 1.000 1.000 1.000 no

R208 1.000 1.571 3/ multidrug

B01n L15079 Q08201 ATP-binding cassette, sub-family B (MDR/TAP), member 4 (P-glycoprotein1.000 no resistance 2

R447 B02a U17133 Q62720 solute carrier family 30 (zinc transporter), member 1 1.046 1.158 1.000 no

R709 O solute carrier family 21 (organic anion transporter), member 5 0.791 1.151 no

B02b U88036 35913 O55224 0.767

R252 1.209

B02c M13979 P11167 Solute carrier family 2 a 1 (facilitated glucose transporter) brain 1.261 0.964 no

R155 B02d J03145 P12336 Solute carrier family 2 A2 (gkucose transporter, type 2) 1.000 1.000 1.448 no

RG272 Q Solute carrier family 2 A3 (neuron glucose transporter) 1.267 1.067 0.967 no

B02e U17978 07647 Q62729

RG432 1.156

B02f D13871 P43427 solute carrier family 2 (facilitated glucose transporter), member 5 0.992 1.228 no

R640 B02g L31621 P04757 Acetylcholine receptor alpha 3 (neuronal nicotine) 1.000 1.000 1.000 no

R486 B02h U53211 Q62962 Amiloride-sensitive cation channel 1, neuronal (degenerin) 1.104 0.772 0.713 no

RG072 B02i J05231 P20420 Acetylcholine receptor alpha 5 1.338 0.887 1.322 no

RG082 B02j L08227 P43143 cholinergic receptor, nicotinic, alpha polypeptide 6 1.112 1.000 1.000 no

RG120 1.000 1.000 1.383 receptor alpha 7) (bungarotoxin alpha)

B02k L31619 Q05941 C holinergic receptor, nicotinic, alpha polypeptide 7 (neuronal nicotinic acetycholine no

RG127 B02l L40624 Q09429 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 1.177 0.983 0.985 no

RG266 B02m U12425 Q64359 Cyclic nucleotide gated cation channel 0.546 0.570 0.548 no

RG286 B02n U32497 P51577 purinergic receptor P2X, ligand-gated ion channel 4 1.036 0.596 0.598 no

RG287 P Sodium channel, nonvoltage-gated 1, beta (epithelial) 0.932 1.523 0.933 no

B03a U35174 37090 O09183

RG302 B03b U59672 Q62999 5-Hydroxytryptamine (serotonin) receptor 3A 0.846 1.489 0.847 no

RG355 B03c X55519 Q00195 Cyclic nucleotide gated channel 4 1.000 1.400 1.000 no

RG391 B03d X74834 P18916 Cholinergic receptor, nicotinic, gamma polypeptide 0.818 1.485 0.820 no

RG392 B03e X74835 P25110 cholinergic receptor, nicotinic, delta polypeptide 0.907 0.971 0.452 no

RG412 B03f X95882 Q64663 purinergic receptor P2X, ligand-gated ion channel, 7 0.951 1.120 0.785 no

RG415 B03g X97328 purinergic receptor P2X, ligand-gated ion channel, 5 1.297 1.107 1.341 no

P51578 Q64613

RG529 B03h X70521 Sodium channel, nonvoltage-gated 1, alpha (epithelial) 2.008 1.384 1.335 no

P37089 Q64593

RG532 B03i X77933 P37091 Sodium channel, nonvoltage-gated 1, gamma (epithelial)2.542 1.022 2.261 no

RG535 B03j X91167 P49654 purinergic receptor P2X ligand-gated ion channel, 3 1.000 1.272 1.000 no

R623 B03k L10077 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)

P12389 O08952 1.000 1.000 1.000 no

R442 P purinergic receptor P2X, ligand-gated ion channel, 2 1.000 1.000 1.000 no

B03l U14414 49653 O54868

RG172 B03m M55250 P24524 glycine receptor, alpha 3 1.000 1.000 1.000 no

R627 1.057

B03n L15453 Q07652 calcium channel, voltage-dependent, L type, alpha 1E subunit 1.259 1.000 no

R359 M84203 potassium

B04a P22462 P22461 P22463 Q63735 channel protein; KSHIIIA3 1.000 1.000 1.000 no

R243 1.128

B04b L77929 Q63511 potassium inwardly-rectifying channel, subfamily J, member 9 0.987 0.797 no

R062 B04c D17521 P51792 protein kinase C-regulated chloride channel 0.676 0.676 0.748 no

R118 B04d D50497 Chloride channel 5

P51796 P70642 1.000 1.000 1.000 no

R103 1.000 1.022

B04e D42145 Q63664 Inwardly rectifying potassium channel gene, subfamily J-8 (ATP sensitive) 1.000 no

R646 1.319

B04f L48619 Q63286 potassium voltage gated channel, Shal-related family, member 2 1.000 1.000 no

R660 B04g M22253 P04774 sodium channel, voltage-gated, type I, alpha 1.090 0.725 0.979 no

R666 B04h M27902 P15389 Sodium channel, voltage-gated, type V, alpha polypeptide 2.169 1.000 1.375 no

R645 B04i L39018 Q63541 sodium channel, voltage-gated, type VIII, alpha polypeptide 2.616 0.803 1.837 no

R677 P Calcium channel alpha 1A

B04j M64373 54282 Q01541 1.362 0.772 0.768 no

R021 B04k AF013598 O35240 proton gated cation channel drasic; sensory neuron specific 0.960 0.984 0.952 no

R540 B04l U94403 P55926 amiloride-sensitive cation channel 2, neuronal 1.286 0.968 0.634 no

R674 0.647

B04m M59980 Q99249 potassium voltage gated channel, Shal-related family, member 2 0.781 0.646 no

RG006 0.835

B04n AF021137 Q64273 potassium inwardly-rectifying channel, subfamily J, member 2 1.120 0.899 no

RG119 B05a L29403 P35560 Potassium inwardly-rectifying channel, subfamily J 0.886 1.184 0.986 no

RG124 0.641

B05b L35771 P48548 potassium inwardly-rectifying channel, subfamily J, member 5 0.722 0.670 no

RG147 B05c M22412 P15383 Potassium (K+) channel protein, slowly activating (Isk) 0.718 0.689 0.870 no

RG152 0.608 1.021

B05d M26161 P10499 voltage-gated potassium channel protein KV1.1; RBK1; RCK1; KCNA1 0.934 no

RG153 B05e M26643 P15390 Sodium channel, voltage-gated, type IV, alpha polypeptide 0.709 0.678 0.737 no

RG177 P27732 Q63491 calcium channel, 0.779

B05f M57682 Q62691 Q01542 O09022 voltage-dependent, L type, alpha 1D subunit 0.753 0.830 no

RG181 P22002 P27733 voltage-dependent 0.999 0.815 1.438 no

B05g M59786 Q62816 Q63271 Q64178 L-type calcium channel alpha 1C subunit (CACNA1); cardiac muscle L-type calcium channel alpha 1 polypeptide isofo

RG193 1.367 0.727 1.097 no

B05h M77482 Q63099 potassium voltage gated channel, Shab-related subfamily, member 2

RG210 B05i M86621 P54290 calcium channel, voltage-dependent, alpha2/delta subunit 1 0.778 0.998 1.176 no

RG219 1.208

B05j M92905 Q02294 calcium channel, voltage-dependent, L type, alpha 1D subunit 0.401 1.130 no

RG288 B05k U37026 P54900 Sodium channel beta 2 1.095 0.798 0.998 no

RG338 1.105 0.757 1.147 no

B05l X16476 P15387 Potassium voltage gated channel, Shab-related subfamily, member 1

RG340 B05m X17621 potassium voltage gated channel, shaker related, subfamily, member 6 1.241 no

P17659 P19025 0.855 0.868

RG378 B05n X62841 Q63734 potassium channel, voltage gated, KV3.4; RAW3; KCNC4 1.144 0.925 1.285 no

RG379 B06a X62894 P35524 Chloride channel 1 (skeletal muscle) 1.113 1.000 1.000 no

RG381 B06b X64139 P35525 chloride channel 2 0.853 0.889 0.724 no

RG399 0.903

B06c X78461 P52188 potassium inwardly-rectifying channel, subfamily J, member 12 0.734 1.054 no

RG407 0.832

B06d X83580 P52190 potassium inwardly-rectifying channel, subfamily J, member 4 0.738 0.633 no

RG408 1.000

B06e X83581 P52191 potassium inwardly-rectifying channel, subfamily J, member 16 1.276 1.000 no

RG409 1.507

B06f X83583 P48550 Potassium inwardly-rectifying, channel, subfamily J, member 6 1.338 1.989 no

RG413 B06g X97041 potassium inwardly-rectifying channel, subfamily J, member 11 0.918 1.409 no

P70673 Q62906 1.263

RG426 B06h Z67744 P51799 Chloride channel 7 2.073 1.532 1.553 no

RG465 B06i M68880 P25122 Potassium channel gene 1 1.567 1.119 1.650 no

RG469 B06j M91808 Q00954 sodium channel, voltage-gated, type I, beta polypeptide 1.505 0.938 1.071 no

RG503 1

B06k X03639 P04775 Sodium channel, voltage-gated, type II, alpha polypeptide.456 0.992 1.106 no

RG512 1.322 1.271 1.000 no

B06l X16001 P15384 potassium voltage gated channel, shaker related subfamily, member 3

RG513 0.744 1.158 0.788 no

B06m X16002 P15385 Potassium voltage gated channel, shaker related subfamily, member 4

RG522 B06n X61394 P54283 calcium channel beta 1 subunit 1.142 1.156 0.812 no

R380 B07a M88751 P54287 Calcium channel subunit beta 3 1.350 1.050 1.343 no

R353 P Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 1.155 no

B07b M79450 31652 P23976 0.927 0.979 (5-hydroxytryptamine (serotonin) transporter)

R355 1.000 1.000

B07c M80570 P23977 Solute carrier family 6 (neurotransmitter transporter, dopamine), member 31.047 no

R376 B07d M88111 P28573 proline transporter 1.038 1.113 1.527 no

R351 1.160 0.889

B07e M77479 P26435 Solute carrier family 10 (sodium/bile acid cotransporter family), member 1 1.104 no

R001 1.218 0.902 1.521 no

B07f AB000113 O08812 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

R378 B07g M88595 P28572 glycine transporter 1 1.314 0.654 1.338 no

R124 1.135

B07h D63834 P53987 Solute carrier 16 (monocarboxylic acid transporter), member 1 0.695 1.073 no

R212 0.573

B07i L19102 Q07782 solute carrier family 13 (sodium/sulphate symporters), member 1 0.805 0.880 no

R202 0.664 2, Na+/H+ (Na+/H+ exchanger 2)

B07j L11004 P48763 Solute carrier family 9 (sodium/hydrogen exchanger 2), antiporter0.664 0.761 no

R116 B07k D50306 P51574 solute carrier family 15 (oligopeptide transporter), member 1 1.084 1.000 1.396 no

R445 B07l U15098 P31596 solute carrier family 1, member 2 1.608 0.887 1.340 no

R459 B07m U28927 P48056 GABA transporter 1.390 1.000 1.145 no

R123 P Solute carrier family 1 A1 (brain glutamate transporter) 1.300 1.114 0.913 no

B07n D63772 51907 Q63727

R400 B08a M95738 P31647 GABA transporter GAT-3 1.037 1.002 1.024 no

RG020 1.002 1.224 1.270 no

B08b D12771 Q09073 Solute carrier family 25, member 5 (adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein))

RG044 B08c D63149 Q63424 solute carrier family 15 (H+/peptide transporter), member 2 0.890 1.282 0.854 no

RG096 0.942

B08d L13257 Q06496 Solute carrier family 17 (sodium/hydrogen exchanger), member 2 1.133 1.147 no

RG180 B08e M59742 P23978 GABA transporter protein 1.206 1.024 0.927 no

RG207 1.513 0.856 (amiloride

B08f M85299 P26431 Solute carrier family 9 (sodium/hydrogen exchanger 1), antiporter, Na+/H+,1.090 nosensitive)

RG208 1.000 3, Na+/H+ (amiloride

B08g M85300 P26433 Solute carrier family 9 (sodium/hydrogen exchanger 3), antiporter1.000 1.000 no insensitive)

RG209 B08h M85301 P26434 sodium/hydrogen exchange protein 4 0.995 1.353 0.854 no

RG226 1.386 1.346

B08i M95762 P31646 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 1.268 no

RG234 B08j S59158 P24942 solute carrier family 1, member 3 1.013 1.546 1.167 no

RG237 B08k S68944 P31662 sodium/chloride neurotransmitter transporter 1.554 0.936 0.857 no

RG256 1.418

B08l U08141 P48768 solute carrier family 8 (sodium/calcium exchanger), member 2 0.856 0.551 no

RG260 1.000 1.182 1.000 no

B08m U10096 P55016 Solute carrier family 12, member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter)

RG261 B08n U10097 P55018 solute carrier family 12, member 3 1.402 1.531 0.916 no

RG283 member 1

B09a U28504 Q62795 solute carrier family 17 vesicular glutamate transporter), 1.000 1.000 1.000 no

RG285 B09b U29881 P53792 low affinity Na-dependent glucose transporter (SGLT2) 1.000 1.000 1.000 no

RG297 0.610 0.820 0.452

B09c U51153 P70545 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 no

RG300 1.000

B09d U53420 P70549 solute carrier family 8 (sodium/calcium exchanger), member 3 1.000 1.000 no

RG447 B09e L22022 Q08469 neurotransmitter transporter, sodium dependent 1.066 1.000 1.000 no

RG471 B09f M96601 P31643 Solute carrier 6 ,member 6 (taurine transporter) 0.964 1.448 1.138 no

RG500 O solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6

B09g U89608 35921 P97683 1.119 1.039 0.804 no

R201 B09h L10362 Q63564 synaptic vesicle glycoprotein 2 b 1.109 1.861 1.196 no

R690 B09i 1.000 1.000 1.000 no

U03120 Q06226 Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter)

R159 B09j J03754 P11506 ATPase isoform 2, Na+K+ transporting, beta polypeptide 2 1.186 1.486 1.536 no

R132 B09k D83598 Q63563 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 4.811 1.000 2.436 no

R282 B09l M28647 Q64609 ATPase, Na+K+ transporting, alpha 1 polypeptide 1.397 1.166 0.703 no

R136 B09m D84450 Q63377 ATPase, Na+K+ transporting, beta polypeptide 3 1.161 1.490 1.118 no

RG017 B09n 1.299 0.844 0.850 no

D10874 P23967 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa

RG052 B10a P09626 ATPase, 0.691 1.136 1.287 no

J02649 P70511 Q63253 H+,K+-transporting, alpha / (gastric H,K-ATPase catalytic subunit)

RG054 B10b J02701 ATPase Na+/K+ transporting beta 1 polypeptide

P07340 Q63062 0.953 1.607 1.709 no

RG061 B10c J03753 P11505 ATPase, Ca++ transporting, plasma membrane 1 0.916 1.059 1.718 no

RG067 B10d J04629 P13638 ATPase, Na+K+ transporting, beta polypeptide 2 1.132 0.893 1.077 no

RG159 B10e M30581 P18596 ATPase, Ca++ transporting, ubiquitous 0.718 1.198 1.409 no

RG174 B10f 0.747 1.004 1.001 no

M55655 P18598 ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR,

RG215 B10g M90398 P54708 ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.186 0.821 1.055 no

RG441 B10h 2

J04022 P11507 ATPase, Ca++ transporting, cardiac muscle, slow twitch 1.126 1.122 1.198 no

RG451 B10i M14512 P06686 ATPase, Na+K+ transporting, alpha 2 polypeptide 0.912 1.144 0.877 no

RG528 B10j X70062 Q04679 FXYD domain-containing ion transport regulator 2 1.043 0.925 1.097 no

RG257 B10k 0.634 1.052

U08344 Q64535 ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease) 0.757 no

R679 B10l 0.800 0.879 0.798

M81855 P43245 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrugno resistance 1)

R188 B10m L05435 Q02563 synaptic vesicle glycoprotein 2 a 1.083 0.760 0.743 no

R401 B10n 0.325

M97381 Q01827 Solute carrier family 18 A2 (vesicular monoamine transporter 2) 0.600 0.255 no

R065 B11a D17695 P47862 aquaporin 3 1.051 1.153 1.000 no

R002 B11b AB000280 O09014 peptide/histidine transporter 1.394 1.396 1.000 no

R346 B11c P Potassium voltage gated channel, shaker related subfamily, member 2

M74449 15386 Q02010 1.019 1.124 0.964 no

R014 B11d AF007775 P56405 aquaporin 8 1.000 1.102 1.000 no

R526 B11e U77971 Q62668 solute carrier family 14, member 2 1.000 1.085 1.075 no

R721 B11f Y09164 P97706 sodium channel, voltage-gated, type VI, alpha polypeptide 1.076 1.000 1.000 no

R426 B11g Q solute carrier family 18 (vesicular monoamine), member 1.629 0.976 1.744 no

U09211 62666 Q64351 3

RG002 B11h AB000507 P56403 aquaporin 7 1.330 1.000 1.833 no

RG070 B11i 1.570 1.131 1.132 no

J05166 P23347 Solute carrier family 4, member 2, anion exchange protein 2

RG108 B11j 1.195

L25264 P35562 Potassium channel, inwarding rectifying, subfamily J, member 3 1.000 1.000 no

RG128 B11k L41254 Q63113 corticosteroid-induced protein 1.519 1.024 1.000 no

RG267 B11l U14007 P47863 Aquaporin 4 1.034 0.968 0.903 no

RG269 B11m U16245 P47864 Aquaporin 5 1.155 0.867 1.217 no

RG310 B11n U89529 P97849 fatty acid transport protein 1.073 0.957 0.853 no

RG385 B12a 28 (CHIP))

X71069 P29975 Aquaporin 1 (aquaporin channel forming integral protein 0.943 0.881 1.426 no

RG433 B12b D13906 P34080 Aquaporin 2 1.279 0.771 1.919 no

RG442 B12c 1.147 0.880 0.902 no

J05167 P23348 Solute carrier family 4, member 3, anion exchange protein 3

RG446 B12d 1

L19031 P46720 solute carrier family (organic anion transporter) member 0.748 0.700 1.379 no

RG497 B12e P97840 Lectin,

U67958 O08588 O35866 galactose binding, soluble 9 (Galectin-9) 0.678 0.828 1.150 no

RG023 B12f 1.009 1.005 0.957 no

D13123 Q06645 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1

RG431 B12g 0.985 0.926 1.026 no

D13124 Q06646 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2

R247 B12h P Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)

M11185 06905 P04400 0.723 1.125 0.663 no

R650 B12i P07722 Myelin-associated glycoprotein

M16800 P07723 P02685 1.030 0.865 1.027 no

R419 B12j U05675 P14480 fibrinogen B beta chain 0.868 0.718 0.854 no

R275 B12k M25889 P02688 Myelin basic protein 0.794 1.236 0.769 no

R667 B12l M27925 Q63537 synapsin II 1.213 1.086 1.054 no

RG039 B12m D38224 P55260 ZAP 36/annexin IV 1.027 0.955 0.683 no

RG105 B12n L20823 Epimorphin

P50279 Q08848 Q08847 Q08846 0.865 0.850 0.867 no

RG225 B13a M95734 P32851 syntaxin 1 a 1.087 0.842 0.519 yes no

RG281 B13b U26402 P47861 synaptotagmin 5 0.998 0.861 0.455 yes yes

R265 B13c P Annexin 1 (p35) (Lipocortin 1)

M19967 07150 Q64664 1.000 1.000 1.000 no

R008 B13d AF000423 O08835 synaptotagmin 11 1.186 1.505 1.432 yes no

R016 B13e AF007836 O35168 Rim1 protein 1.021 1.437 0.920 no

RG474 B13f S73557 Q07936 calpactin I heavy chain 0.682 0.973 0.648 no

R604 B13g Y13380 O08839 myc box dependent interacting protein 1 0.957 1.046 0.737 no

RG060 B13h J03577 gastric intrinsic factor

P17267 O35801 0.810 0.894 0.796 no

RG123 B13i L34049 P98158 glycoprotein 330 1.175 1.000 1.000 no

R605 B13j Y13381 O08838 amphiphysin 1.001 1.676 0.849 no

R420 Q Syntaxin binding protein 1

B13k U06069 64320 Q62759 1.167 0.823 0.410 yes yes

R239 B13l L38247 P50232 synaptotagmin 4 0.709 0.942 0.718 no

R664 B13m M27812 P09951 Synapsin I 1.576 1.071 0.899 yes no

R390 B13n M93669 P10362 Secretogranin II 1.033 2.020 1.826 no

R661 B14a M24104 Q63666 Vesicle-associated membrane protein (synaptobrevin 2)0.727 0.567 1.555 no

R662 B14b M24105 Q64357 Vesicle-associated membrane protein (synaptobrevin 2)0.731 0.980 0.779 no

R439 B14c U13253 fatty 1.018 1.123 1.191 (C-FABP); DA11

P55053 P97757 acid-binding protein (epidermal; E-FABP); cutaneous fatty acid- binding protein no

R302 B14d M35991 P02692 Fatty acid binding protein 1, liver 1.457 1.000 2.628 no

R150 B14e J02773 P07483 heart fatty acid binding protein 1.035 0.755 0.908 no

R303 B14f M35992 P02693 Fatty acid binding protein 2 0.498 0.928 1.015 no

R672 P Sterol

B14g M34728 11915 Q63383 carrier protein 2, liver 0.847 1.246 1.260 no

R707 B14h U75581 P70623 adipocyte lipid-binding protein 1.507 1.000 1.984 no

R691 B14i U07870 P55054 testis lipid binding protein 1.000 1.000 1.905 no

RG346 B14j X52772 P21707 Synaptotagmin 1 0.848 0.917 0.880 no

RG463 B14k M64488 P29101 Synaptotagmin II 1.056 1.126 1.512 no

RG034 B14l D28512 P40748 Synaptotagmin 3 1.055 1.345 1.048 no

RG102 B14m L20820 Q08849 syntaxin 3 1.000 1.942 2.069 no

RG103 B14n L20821 Q08850 syntaxin 4 1.075 1.465 1.619 no

RG104 C01a L20822 Q08851 syntaxin 5a 1.051 1.205 1.238 no

RG301 C01b U56815 Q63635 syntaxin 6 1.375 1.322 1.461 no

RG470 C01c M95735 P32853 Syntaxin 2 1.160 1.099 0.994 no

RG229 1.168 0.869 1.012 transporter)

C01d M97380 Q01818 Solute carrier family18 (vesicular monoamine) member 1 (chromaffin granule amine no

RG235 C01e S63830 Q64271 vesicle-associated membrane protein 3 0.737 0.729 0.696 no

RG248 C01f U02096 P55051 fatty acid binding protein 7, brain 0.669 1.157 1.195 no

RG275 C01g U20283 Q62753 syntaxin binding protein Munc18-2 1.065 1.104 1.091 no

RG427 P13795 P36974

C01h AB003991 Synaptosomal-associated protein, 25 kDa 0.886 1.395 1.028 no

RG487 C01i U38370 P54256 huntingtin-associated protein 1 0.848 0.691 0.641 no

RG505 C01j X06655 P07825 Synaptophysin 1.160 1.038 0.629 yes no

R092 C01k D32249 Q63364 rotein carrying the RING-H2 sequence motif 0.867 0.996 0.909 no

RG059 C01l J02998 P05711 ras-related protein 0.848 1.502 1.260 no

RG202 C01m M83678 P35286 RAB13 0.882 1.205 1.436 no

RG388 C01n X74401 P50399 guanosine diphosphate (GDP) dissociation inhibitor 3 0.709 1.227 0.741 no

R425 C02a U07952 P50398 GDP-dissociation inhibitor 1 0.859 0.738 0.636 no

RG343 C02b X52625 P17425 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 0.701 0.727 0.456 no

RG066 C02c J04526 P05708 Hexokinase 1 0.936 1.081 0.943 no

RG110 C02d L26009 Q10980 Alpha1,2-fucosyltransferase a 1.000 1.119 1.000 no

RG111 C02e L26010 Q10984 fucosyltransferase 2 1.000 1.158 1.019 no

RG129 P Aldolase B, fructose-biphosphate

C02f M10149 00884 P70706 1.000 1.135 1.145 no

RG131 C02g M12919 P05065 Aldolase A, fructose-bisphosphate 1.298 0.958 0.935 no

RG049 C02h D90109 P18163 fatty acid Coenzyme A ligase, long chain 2 0.956 1.282 0.640 no

RG325 C02i X06984 P09117 Aldolase C, fructose-biphosphate 0.868 1.430 0.775 no

RG186 C02j M64797 P25114 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.567 0.770 0.259 no

RG335 C02k X15546 P23739 Sucrase-isomaltase 1.000 1.087 1.279 no

RG467 P Fructose-1,6- biphosphatase

C02l M86240 19112 Q64594 0.996 1.392 0.996 no

R026 0.985 1.119 0.627 no

C02m AF019973 P07323 neuron-specific enolase (NSE); gamma enolase (EC 4.2.1.11); 2-phospho-D-glycerate hydrolyase

RG019 C02n D10952 P12075 cytochrome c oxidase subunit Vb 0.981 1.205 0.993 no

RG024 C03a D13205 P00173 cytochrome b5 0.558 0.693 0.891 no

RG056 1.000

C03b J02791 P08503 Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain 1.000 1.255 no

RG132 C03c M15327 P06757 Alcohol dehydrogenase (class I), alpha polypeptide 1.000 1.000 1.646 no

RG142 C03d M20623 P10715 Cytochrome C, testis specific 0.712 0.535 0.796 no

RG164 0.543 0.684 0.443 3-hydroxy-3-methylglutaryl-CoA synthase; HMGCS2

C03e M33648 P22791 mitochondrial hydroxymethylglutaryl-CoA synthase precursor (HMG-CoA synthase); no

RG244 C03f S79304 P05503 cytochrome oxidase, subunit I, Sertoli cells 0.432 0.934 0.501 no

RG295 C03g U43175 P50408 ATPase, vacuolar, 14 kD 0.978 1.359 1.029 no

RG329 C03h X12554 P10817 Cytochrome c oxidase subunit VIa polypeptide 2 (heart) 1.230 1.313 1.429 no

RG330 C03i X14209 P10888 cytochrome c oxidase, subunit IVa 0.846 1.065 0.726 no

RG333 C03j X15030 P11240 cytochrome c oxidase, subunit Va, mitochondrial 0.677 0.767 0.399 no

RG350 C03k X54080 P35171 cytochrome c oxidase subunit VIIa 3 0.974 0.839 0.807 no

RG382 C03l X64827 P16221 Cytochrome c oxidase subunit VIII-H (heart/muscle) 0.749 0.869 0.452 no

RG507 C03m X07467 P05370 Glucose-6-phosphate dehydrogenase 1.332 0.843 1.188 no

RG418 C03n Y10054 P97519 3-hydroxy-3-methylglutaryl CoA lyase 1.020 1.293 0.520 no

RG011 C04a D10021 P31399 ATP synthase subunit d 0.636 1.160 0.679 no

RG139 0.702 1.045 0.531 no

C04b M19044 P10719 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide

RG169 0.431 0.602 0.257 no

C04c M35052 P19511 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1

RG518 C04d X56133 P15999 mitochondrial H+-ATP synthase alpha subunit 0.245 0.894 0.208 no

RG047 Q64559 brain acyl-CoA hydrolase

C04e D88890 O09041 O08652 0.837 1.011 0.672 no

RG455 1.473 1.438 0.982 no

C04f M32801 P21775 Acetyl-CoA acyltransferase, 3-oxo acyl-CoA thiolase A 1, peroxisomal

RG369 C04g X59737 P25809 creatine kinase, mitochondrial 1, ubiquitous 1.271 1.414 0.690 no

R311 1.083 1.000 1.000 no

C04h M38566 P17178 sterol 26-hydroxylase mitochondrial precursor (EC 1.14.-.-); vitamin D(3) 25-hydroxylase; 5-beta-cholestane-3-alpha,7-alpha,12-alpha-tri

R350 M76767 fatty acid synthase

C04i P12785 Q64717 O09187 O09190 1.829 1.356 0.965 no

R199 C04j L09216 P54318 pancreatic lipase-related protein 2 1.130 1.000 1.000 no

R474 C04k U40001 Q05469 Hormone - sensitive lipase, testicular isoform 1.000 1.000 1.000 no

R257 C04l M16235 P07867 Lipase, hepatic 1.163 1.000 1.000 no

R320 C04m M58369 P27657 Pancreatic lipase 1.223 1.000 1.282 no

R141 C04n D88666 P97535 phosphatidylserine-specific phospholipase A1 1.839 1.290 1.590 no

R321 C05a M58370 P17084 Colipase pancreatic 1.000 1.000 1.000 no

R161 C05b J03808 acetyl-coenzyme A carboxylase

P11497 P97902 1.000 1.000 1.000 no

R194 C05c L07736 Carnitine palmitoyltransferase 1 alpha, liver isoform

P32198 P97780 0.384 0.552 0.387 no

RG012 P33124 ( Q63835?) acid Coenzyme A ligase, long chain 6

C05d D10041 fatty 0.302 0.943 0.359 no

RG040 C05e D43623 Q63704 Carnitine palmitoyltransferase 1 beta, muscle isoform 1.000 1.000 1.000 no

RG306 C05f U64451 P70584 Acyl-Coenzyme A dehydrogenase, short-branched chain 0.724 0.714 0.726 no

R559 C05g X16054 Carboxyl ester lipase

P07882 P14722 2.680 0.720 2.040 no

R222 C05h L26043 P43884 Perilipin 1.000 1.000 1.000 no

R398 C05i M95058 P31214 steroid 5-alpha-reductase 2 2.385 1.000 2.352 no

R233 C05j L32601 P51652 20 alpha-hydroxysteroid dehydrogenase 1.000 1.000 1.073 no

R184 C05k L03294 Q06000 Lipoprotein lipase 1.000 1.000 1.000 no

R169 C05l J05107 P16232 Hydroxysteroid dehydrogenase, 11 beta type 1 0.843 1.181 1.409 no

R170 C05m J05156 P14137 cytochrome P450, 11a, cholesterol side chain cleavage 1.988 1.000 1.231 no

R164 C05n J03960 P12527 arachidonate 5-lipoxygenase 4.060 1.848 2.681 no

R469 C06a U37138 P15589 Steroid sulfatase 0.906 1.018 0.739 no

R502 C06b U62803 O35849 Lecithin-cholesterol acyltransferase 0.997 1.495 0.812 no

R518 C06c U72497 P97612 fatty acid amide hydrolase 0.953 0.820 0.710 no

R343 1.000 1.478 1.000 no

C06d M67465 P27364 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase

R574 C06e X63410 P22789 Rat senescence marker protein 2A gene, exons 1 and 21.370 1.249 1.000 no

R424 C06f U07683 Q09426 UDP-glucuronosyltransferase 8 1.620 0.677 1.465 no

R536 C06g U90556 O08564 phosphatidate phosphohydrolase type 2a 0.831 1.090 0.691 no

RG038 C06h D37920 P52020 squalene epoxidase 0.921 0.913 0.922 no

RG141 C06i M20559 P14669 Annexin A3 2.617 1.721 1.781 no

RG143 C06j M21208 P11715 Cytochrome P450, subfamily XVII 1.506 1.011 1.000 no

RG189 C06k M73714 P30839 alcohol dehydrogenase family 3, subfamily A2 0.807 0.799 0.809 no

RG224 C06l M95591 Q02769 farnesyl diphosphate farnesyl transferase 1 0.769 0.683 0.398 no

RG245 1.000 1.032 1.000 no

C06m S81448 P24008 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1); steroid 5-alpha-reductase 1 (SR type 1)

RG457 C06n M33986 P22443 Cytochrome P450, 19, aromatase 1.221 2.229 0.963 no

RG460 0.854 1.021 0.847 no

C07a M38178 P22071 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase

RG053 P08683 Cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase) 1.048 1.000 no

C07b J02657 Q63141 Q64554 1.506

RG057 1.144 1.036 0.926

C07c J02852 P20812 Cytochrome P450, subfamily IIA (phenobarbital-inducble)/ (Cytochrome P450 IIA3) no

RG130 P cytochrome P450 3A1 (CYP3A1); P450-PCN1

C07d M10161 04800 Q64580 1.411 1.127 1.337 no

RG138 C07e M18335 P05179 cytochrome P450, 2c39 1.513 1.000 1.251 no

RG165 1.229 P450-LA-omega

C07f M33936 P20817 cytochrome P450 4A3 (CYP4A3); lauric acid omega-hydroxylase;1.223 1.721 3no

RG171 C07g M37828 P24464 cytochrome P450, 4a10 1.273 0.956 1.726 no

RG178 C07h M58041 P19225 cytochrome P450 2c22 0.741 0.736 1.058 no

RG223 C07i M94548 P33274 cytochrome P450 4F1 1.102 0.769 0.972 no

RG291 C07j U39206 P51869 cytochrome P-450 4F4 0.988 0.769 0.902 no

RG292 C07k U39943 P51590 cytochrome P-450 2J3 1.102 1.232 1.572 no

RG304 P51538 cytochrome P-450 3A9, olfactory

C07l U60085 Q64631 Q64557 1.261 1.490 1.295 no

RG326 C07m X07259 P08516 Cytochrome P450, subfamily IVB, polypeptide 1 1.000 1.000 1.305 no

RG417 C07n Y08172 P70473 alpha-methylacyl-CoA racemase 0.795 1.822 0.797 no

RG489 C08a U39207 P51870 cytochrome P-450 4F5 0.526 0.646 0.609 no

RG490 C08b U39208 P51871 cytochrome P-450 4F6 1.039 1.180 0.790 no

RG516 P24470 arachidonic acid epoxygenase

C08c X55446 Q64534 Q63914 0.921 0.939 0.922 no

R148 1.000

C08d J02669 P11711 Cytochrome P450 IIA1 (hepatic steroid hydroxylase IIA1) gene 1.000 1.000 no

R189 C08e L06040 Q02759 arachidonate 12-lipoxygenase 0.963 1.627 1.346 no

RG303 C08f U60063 Q63639 aldehyde dehydrogenase family 1, subfamily A2 0.785 1.156 0.730 no

R125 C08g D63885 P70470 Lysophospholipase 1.226 1.094 21.500 no

RG022 C08h D13061 P29410 Adenylate kinase 2 0.833 0.868 0.835 no

RG026 C08i D13376 P39069 Adenylate kinase 1 1.139 1.227 0.727 no

RG090 C08j L12138 P45352 thymidylate synthase 0.997 0.914 0.894 no

RG150 C08k M22642 P27158 Thymidine kinase 1 0.958 0.985 0.577 no

RG430 C08l D13062 P29411 adenylate kinase 3 0.830 1.112 0.358 no

R260 C08m M17086 P09456 Protein kinase, cAMP dependent, regulatory, type 1 0.853 1.236 0.679 no

R280 C08n M27716 P14173 Dopa decarboxylase (aromatic L-amino acid decarboxylase)1.236 1.144 1.000 no

RG055 C09a J02720 P07824 arginase 1, liver 1.018 0.727 0.739 no

RG071 C09b J05181 P19468 Glutamylcysteine gamma synthetase light chain 1.033 0.723 0.713 no

RG073 C09c J05470 Carnitine palmitoyltransferase 2

P18886 P97781 0.711 0.690 0.440 no

RG106 C09d L22191 P48508 glutamate-cysteine ligase , modifier subunit 1.047 0.679 0.685 no

RG126 C09e L38615 P46413 Glutathione synthetase gene 1.412 0.909 0.984 no

RG501 O arginase type II

C09f U90887 08701 P97539 0.892 0.875 1.433 no

RG488 C09g U38419 P52847 dopa/tyrosine sulfotransferase 0.957 0.877 3.151 no

RG167 C09h M34445 P18088 Glutamate decarboxylase 1 (brain) 0.766 1.108 0.840 no

RG188 C09i M72422 Q05683 Glutamate decarboxylase 2 (islet) 0.953 1.034 1.634 no

R520 C09j U73174 P70619 glutathione reductase 0.784 0.936 0.875 no

R168 C09k J05029 P15650 Acyl Coenzyme A dehydrogenase, long chain 1.278 1.374 1.189 no

RG036 C09l D30647 P45953 Acyl-Coa dehydrogenase, Very long chain 1.344 1.392 0.844 no

RG069 C09m J05030 P15651 short chain acyl-coenzyme A dehydrogenase 1.070 1.392 0.777 no

RG436 C09n J02752 acyl-coA oxidase

P07872 P11354 0.638 0.883 0.442 no

R556 P02593 P99014 Calmodulin III

C10a X13817 P70667 Q61379 Q61380 0.655 0.768 0.791 no

RG062 C10b J03959 P09118 urate oxidase 1.000 1.000 1.000 no

RG122 C10c L33869 Ceruloplasmin (ferroxidase)

P13635 Q64719 1.047 0.982 1.152 no

RG148 P carbonic anhydrase 3

C10d M22413 14141 Q54961 1.307 1.000 1.050 no

RG236 C10e S68245 P48284 carbonic anhydrase 4 0.977 0.997 1.076 no

RG265 C10f U12268 P43165 carbonic anhydrase 5 1.000 1.000 1.000 no

RG278 C10g U22424 P50233 Hydroxysteroid dehydrogenase, 11 beta type 2 1.058 1.000 1.184 no

RG284 C10h U29701 P50554 4-aminobutyrate aminotransferase 1.049 0.786 0.597 no

RG332 C10i X14977 P11884 aldehyde dehydrogenase 2, mitochondrial 0.995 0.741 0.706 no

RG439 C10j J03572 Tissue-nonspecific ALP alkaline phosphatase

P08289 P14055 1.376 0.853 0.825 no

RG445 1.738

C10k L12407 Q05754 Dopamine beta hydroxylase (dopamine beta-monooxygenase) 1.000 1.000 no

RG473 C10l S73007 P37136 synuclein, alpha 0.955 0.961 0.549 no

RG016 0.814

C10m D10854 P51635 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.931 0.528 no

RG249 C10n U02534 Q62600 nitric oxide synthase 3 1.085 1.292 0.801 no

R332 C11a M62388 P23567 ubiquitin conjugating enzyme 0.842 1.396 1.440 no

R365 0.681 1.252 1.686 no

C11b M86870 P38659 protein disulfide isomerase related protein (calcium-binding protein, intestinal-related)

R467 C11c U36580 Q62849 proprotein convertase subtilisin/kexin type 7 1.000 1.000 1.662 no

R263 P large

C11d M19635 09896 P10661 subunit ribosomal protein L36a 0.626 0.667 0.776 no

R656 P ribosomal protein S12

C11e M18547 09388 P12728 0.861 0.841 1.044 no

RG331 P12750 P12631 ribosomal protein

C11f X14210 P27576 P55831 Q14727 S4, X-linked 0.423 0.580 0.461 no

RG375 C11g X62146 P25121 ribosomal protein L11 0.497 0.673 0.488 no

RG398 C11h X78327 P41123 ribosomal protein L13 0.900 1.143 1.375 no

RG411 C11i X87106 P45634 ribosomal protein L10 0.836 1.024 0.846 no

RG515 C11j X53504 P23358 ribosomal protein L12 0.879 1.000 1.043 no

R561 C11k X51707 P17074 ribosomal protein S19 1.484 1.000 1.748 no

R281 C11l M27905 P20280 ribosomal protein L21 0.995 1.573 1.416 no

R147 C11m J02650 P14118 ribosomal protein L19 0.877 1.113 0.959 no

R174 C11n K03250 P04643 ribosomal protein S11 0.721 1.051 0.710 no

R173 C12a K02933 P04644 ribosomal protein S17 0.915 0.829 0.862 no

R362 P ribosomal protein S3a

C12b M84716 49242 P33443 0.869 1.246 1.342 no

R205 C12c L11651 Q07205 eukaryotic initiation factor 5 (eIF-5) 0.828 0.776 0.642 no

RG077 C12d K03502 eukaryotic translation elongation factor 2

P05197 P97619 1.032 0.860 0.823 no

RG098 C12e L14684 Q07803 G elongation factor 1.000 1.233 1.000 no

RG406 C12f X83399 P20415 eukaryotic translation initiation factor 4E 1.000 1.000 1.000 no

R146 )

C12g J02646 P05199 eukaryotic translation initiation factor 2, subunit 1 (alpha 0.696 0.830 0.652 no

R011 C12h AF003523 O35147 bcl-2 associated death agonist 0.719 0.556 0.411 no

R482 Q63690 Bcl2-associated X protein

C12i U49729 Q62995 Q64383 0.706 0.706 0.272 no

R207 P49950 B cell lymphoma 2 associated oncogene

C12j L14680 Q62837 Q64032 1.000 1.000 1.000 no

R516 U72350 B P70614

C12k P53563 Q62678 P70613cell lymphoma 2 like 1.682 1.096 0.753 no

R341 C12l M64723 P05371 Clusterin 1.099 0.910 0.822 no

R133 0.574

C12m D83697 P70678 BH3 interacting (with BCL2 family) domain, apoptosis agonist 1.184 0.442 no

RG247 C12n U01022 P51111 Huntington disease gene homolog 1.000 1.597 1.000 no

R588 C13a X80477 P47824 Purinergic receptor P2X, ligand-gated ion channel, 1 1.325 0.916 0.960 no

R066 Q heterogeneous nuclear ribonucleoprotein K

C13b D17711 07244 Q15671 0.805 1.352 1.462 yes no

R521 C13c U75369 O35876 survival motor neuron 1.484 1.184 1.464 no

R192 C13d L07114 P38483 Apolipoprotein B editing protein 3.412 1.000 2.251 no

R135 C13e D84418 P52925 high mobility group box 2 1.000 1.000 1.000 no

R408 0.531 0.655 0.613 no

C13f S68987 Q63945 Set beta isoform + Set alpha isoform; neural plasticity-related protein

RG464 P07155 High mobility group 1

C13g M64986 P27109 P27428 0.361 1.040 0.566 yes no

R352 C13h M77809 P26342 transforming growth factor, beta receptor III 1.000 1.000 1.000 no

R538 C13i U93306 O08775 FLK1 kinase insert domain receptor (VEGF receptor 2) 1.000 1.000 1.000 no

R548 C13j X05137 P07174 Nerve growth factor receptor, fast 1.000 1.000 1.000 no

R046 C13k D13566 Q07303 Erythropoietin receptor 2.804 0.986 2.075 no

R686 C13l M91599 Q63709 Fibroblast growth factor receptor 4 2.994 0.697 2.514 no

R543 C13m U97142 Q62997 Glial cell line-derived neurotrophic factor receptor alpha 0.184 0.897 0.205 no

R544 C13n U97143 O35977 Tyrosine kinase receptor ligand 2 0.897 0.905 0.482 no

R505 C14a U65007 P97579 Met proto-oncogene 1.436 1.582 0.879 no

R495 Q Insulin-like growth factor 2 receptor

C14b U59809 63002 Q63757 2.094 1.753 4.358 no

R335 C14c M63837 P20786 Platelet-derived growth factor receptor alpha 1.357 0.830 1.069 no

R078 1.079 0.960 0.965 no

C14d D28498 P53767 Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

R673 Q63604 Neural

C14e M55291 Q63605 Q63606 receptor protein-tyrosine kinase (trkB) 1.159 1.023 0.985 no

R094 C14f D38082 Q64308 bone morphogenetic protein type IA receptor 0.992 2.199 0.992 no

R223 C14g L26110 P80204 transforming growth factor, beta receptor I 0.947 0.913 0.948 no

1.000 1.000 1.000 no

R310 C14h M37394 Q9QX70 Epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)

R200 C14i L09653 P38438 transforming growth factor-b type II receptor 1.007 1.000 1.000 no

R639 C14j L29232 P24062 Insulin-like growth factor 1 receptor 1.000 1.068 1.000 no

R515 C14k U69278 O08680 Eph receptor A3 3.043 1.000 2.777 no

R587 C14l X78689 P08154 eck-like sequence 1 3.498 1.342 2.827 no

R453 C14m U21954 P54759 EphA7 0.772 1.353 1.065 no

RG298 C14n U52531 Q62956 receptor tyrosine kinase 0.834 1.465 0.836 no

RG368 D01a X59290 P29321 eph and elk-related kinase 1.000 1.016 1.032 no

RG422 D01b Z14119 Q05030 Platelet-derived growth factor receptor, beta 1.207 1.299 0.993 no

R572 D01c X61479 Q00495 Colony stimulating factor 1 receptor 1.354 0.933 1.017 no

R327 D01d M60786 P26684 Endothelin receptor type A 1.426 1.000 1.436 no

R487 D01e U54791 Q62973 Chemokine receptor (LCR1) 1.236 0.992 0.863 no

RG004 D01f AB003042 complement component 5, receptor 1

P97520 O09088 1.071 1.026 0.721 no

RG362 D01g X57764 P21451 endothelin receptor 1.323 1.333 0.843 no

RG311 D01h U92802 O08878 G protein-coupled receptor 30 1.000 0.977 1.144 no

R314 D01i M55050 P26896 Interleukin 2 receptor, beta chain 0.935 0.939 0.850 no

R584 D01j X69903 Q63257 Interleukin 4 receptor 0.710 0.671 0.626 no

R399 D01k M95578 Q02955 Interleukin 1 receptor, type I 0.886 0.684 0.683 no

R414 D01l U04317 Q62611 Interleukin 1 receptor-like 1 (Fos-responsive gene 1) 0.940 1.041 0.792 no

RG397 D01m X77797 P35407 chemokine (C-X-C) receptor 2 1.099 0.815 0.980 no

R157 D01n J03624 P10683 galanin 0.892 1.016 0.745 no

R537 D02a U92289 O35932 prostaglandin D2 receptor 0.743 0.720 0.824 no

R167 D02b J04811 P16310 Growth hormone receptor 1.090 1.030 1.028 no

P

R668 D02c M29014 15127 P97681 Insulin receptor 0.723 0.667 0.743 no

Q62959 Q63007 Leptin O54805

R725 D02d D84550 P70493 Q63385receptor (fatty) 0.884 0.911 0.904 no

D02e U57439 Estrogen receptor 2

R491 Q62986 O70195 O35785 O55015 O55016 O35784 (ER beta) 0.789 0.781 1.077 no

R507 D02f U66107 P97583 B1 bradykinin receptor 0.754 0.729 0.785 no

R363 D02g M85183 Q63035 angiotensin/vasopressin receptor 1.000 1.000 1.072 no

RG117 D02h L27339 P41740 Atrial natriuretic peptide clearence receptor 3 0.975 0.976 1.168 no

RG519 D02i X58375 P35570 Insulin receptor substrate 1 1.296 1.000 1.106 no

RG523 D02j X62314 P28646 Somatostatin receptor subtype 1 1.551 1.200 0.939 no

RG239 D02k S70690 cholecystokinin 1.453 1.153 0.882 no

RG029 D02l D16102 Q63060 Glycerol kinase 1.386 1.055 0.952 no

R347 D02m M74535 P18910 Natriuretic peptide receptor A/Guanylate cyclase A 1.683 1.677 0.946 no

R407 D02n S48190 P38444 activin type receptor 1.600 1.180 1.000 no

RG100 D03a L19341 P80201 activin type I receptor 1.072 1.000 1.000 no

R183 D03b L03202 P31388 5-hydroxytryptamine (serotonin) receptor 6 0.877 0.983 0.917 no

R309 D03c M36831 P13953 Dopamine receptor D2 1.110 0.836 0.985 no

R358 D03d M84009 P30729 Dopamine receptor D4 1.327 1.019 1.000 no

R059 D03e D16829 P34975 opioid receptor, kappa 1 0.861 0.955 0.887 no

R633 L20684 Opioid receptor, mu 1

D03f P33535 Q64064 Q62846 Q64120 1.000 1.065 1.174 no

1 receptor), see 1.000 no

R288 D03g M31477 P14600 Tachykinin 1 receptor (substance P receptor, neurokinin1.069 1.004 also D4Mgh17, D4Wox19 and D4Mit23

R403 D03h M99418 P30553 Cholecystokinin B receptor 1.259 1.064 1.165 no

R688 D03i U00475 P33533 Opioid receptor delta 1 0.962 1.075 0.861 no

R290 D03j M31838 P16610 Tachykinin 2 (substance K) receptor 1.016 1.287 1.266 no

R567 D03k X56661 P52500 Gastrin-releasing peptide receptor 0.899 1.367 1.000 no

R171 D03l J05189 P16177 Neuromedin K receptor (Neurokinin B/Tachikin 3) 1.119 1.327 1.144 no

R231 D03m L31771 P23944 adrenergic receptor, alpha 1d 1.487 1.191 1.098 no

R186 D03n L04796 P30082 glucagon receptor 1.079 1.174 1.000 no

R625 D04a L14617 calcitonin receptor

P32214 P32213 1.210 1.338 1.000 no

R416 D04b U04740 P46002 platelet-activating factor receptor 1.000 1.140 0.785 no

R110 D04c D45400 P48974 arginine vasopressin receptor 1B 1.000 1.136 1.000 no

R479 P Prostaglandin F receptor

D04d U47287 43118 Q62787 1.052 1.565 0.953 no

R277 P16235 P70646 Luteinizing hormone/choriogonadotropin receptor

D04e M26199 Q63807 Q63808 Q63809 1.239 0.973 0.985 no

R284 D04f M30705 P14842 5-hydroxytryptamine (serotonin) receptor 2 A 0.857 1.116 0.810 no

R297 D04g M34842 P21463 Thyroid stimulating hormone receptor 1.000 1.051 1.257 no

R410 D04h U00935 P30969 gonadotropin-releasing hormone receptor 1.134 1.000 1.020 no

R415 1.157 1.050 1.035 no

D04i U04738 P30937 Somatostatin receptor subtype 4 Rattus norvegicus Sprague-Dawley major hippocampal somatostatin receptor (SSTR4) mRNA

R517 D04j U72487 O35818 CL1BA protein 1.249 0.787 0.817 no

R440 D04k U13368 P43140 adrenergic receptor, alpha 1c 1.530 1.119 1.013 no

R446 D04l U16253 P47866 corticotropin-releasing factor receptor subtype 2 0.999 1.033 0.655 no

R489 D04m U55836 P70555 parathyroid hormone receptor 2 1.301 0.848 0.830 no

R180 D04n L02842 P20395 Follicle stimulating hormone receptor 1.103 0.970 1.079 no

R710 D05a U94708 Q62928 prostaglandin E receptor EP2 subtype 0.978 1.294 1.533 no

R061 D05b D17469 Q01717 Thyrotropin releasing hormone receptor 1.114 1.225 1.000 no

R541 P prostaglandin E receptor 4 (subtype EP4)

D05c U94709 43114 O08728 0.987 0.796 1.106 no

RG003 D05d AB001982 O08725 growth hormone secretagogue receptor 0.874 0.999 0.979 no

RG010 D05e D00634 P18090 Adrenergic receptor beta 1 1.372 1.221 1.495 no

RG028 P34980 Rat kidney prostaglandin EP3 receptor

D05f D14869 Q63194 Q64376 1.108 0.666 0.859 no

RG031 D05g D16840 P35351 Angiotensin receptor 2 1.000 1.000 1.193 no

RG033 D05h D21158 P34978 Thromboxane receptor 1.000 1.000 1.000 no

RG037 P Adrenergic, alpha 1B-, receptor

D05i D32045 15823 Q63215 0.816 0.723 0.885 no

RG046 D05j D88752 Prostaglandin E receptor 1 (subtype EP1)

P70597 P97537 1.054 0.793 0.893 no

RG078 D05k L04535 P30938 Somatostatin receptor subtype 5 0.950 2.201 0.882 no

RG080 D05l L05596 P30940 5-hydroxytryptamine (serotonin) receptor 1F 0.916 0.668 0.765 no

RG089 D05m L10072 P35364 5-hydroxytryptamine (serotonin) receptor 5A 1.159 0.994 1.454 no

RG101 D05n L19475 P25961 parathyroid hormone receptor 1.000 1.037 1.039 no

RG145 D06a M21410 P08909 5-hydroxytryptamine (serotonin) receptor 2C 0.632 1.121 0.691 no

RG163 P Adrenergic, alpha2B-, receptor class III

D06b M32061 19328 Q63021 0.829 0.953 0.997 no

RG179 D06c M58316 P22086 Adrenergic, alpha2C-, receptor class I 0.811 1.259 1.170 no

RG211 D06d M88096 P30551 Cholecystokinin A receptor 0.896 1.117 1.387 no

RG214 D06e M89954 P28564 Serotonin (5-hydroxytryptamine (5HT)) receptor, type 1B 0.996 1.073 1.406 no

RG222 D06f M93273 P30936 somatostatin receptor subtype 2 0.841 1.157 1.264 no

RG253 D06g U05239 P35370 opioid receptor-like 0.835 1.131 1.467 no

RG268 D06h U14409 P49218 melatonin receptor 1A 0.884 0.949 1.374 no

RG276 Q62758 5-HT4

D06i U20907 Q62757 Q63006receptor (two splicing variants L and S) 0.580 0.807 0.761 no

RG289 D06j U37058 P24053 Neuromedin B receptor 0.928 1.013 1.000 no

RG293 D06k U40395 P20272 Cannabinoid receptor 1 0.987 1.056 1.073 no

RG294 Q pancreatic polypeptide receptor 1

D06l U42388 63447 Q62892 1.048 1.007 1.024 no

RG312 D06m U94322 O08726 galanin receptor 2 0.738 0.828 1.236 no

RG367 D06n X59132 P23811 secretin receptor 0.945 1.197 0.900 no

RG414 D07a X97121 Q63384 NTR2 receptor 1.334 1.024 1.240 no

RG419 D07b Z11504 P21555 neuropeptide Y receptor Y1 0.899 1.004 1.185 no

RG420 D07c Z11690 P30560 Vasopressin receptor V1a 1.113 1.000 1.223 no

RG421 D07d Z11932 Q00788 Vasopressin receptor V2 0.948 0.796 0.559 no

RG438 D07e J03024 P10608 Adrenergic, beta 2-, receptor, surface 1.079 1.034 1.059 no

RG443 D07f L10073 P35365 5-hydroxytryptamine (serotonin) receptor 5B 1.086 1.228 1.195 no

RG468 D07g M86835 P30083 Vasopressive intestinal peptide receptor 1.217 0.995 1.023 no

RG475 D07h S75952 Pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1 no

P32301 Q64073 1.092 1.270 0.913

RG486 D07i U30290 Q62805 Galanin receptor 1 0.904 0.977 0.857 no

RG493 D07j U52218 Q62953 G protein-coupled receptor 50 0.888 1.292 0.881 no

RG495 Q Neuropeptide Y5 receptor

D07k U66274 63634 P70586 1.004 1.313 0.834 no

RG496 D07l U67863 P70596 Melanocortin 4 receptor 1.132 0.922 0.507 no

RG525 D07m X63574 P30936 somatostatin receptor 28 1.459 1.278 1.312 no

RG527 D07n X66842 P30994 5-hydroxytryptamine (serotonin) receptor 2B 0.967 0.953 0.913 no

R298 P Dopamine-1A receptor

D08a M35077 18901 P21669 0.686 1.293 0.910 no

R431 D08b U09631 P35000 vasoactive intestinal peptide receptor 2 0.943 0.787 0.997 no

R715 P16416 thyroid

D08c X12744 P10685 Q63107 hormone receptor alpha 1.615 1.099 1.676 no

R357 D08d M81766 P49743 Retinoic acid receptor, beta 1.247 0.704 0.690 no

R163 0.732 0.809 0.921 no

D08e J03933 P18113 Thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)

R304 P22199 Mineralocorticoid receptor (aldosterone receptor)

D08f M36074 Q63763 Q64174 0.898 0.843 0.911 no

R254 D08g M14053 P06536 nuclear receptor subfamily 3, group C, member 1 1.055 0.983 1.144 no

RG064 D08h J04147 P13053 Vitamin D (1,25-dihydroxyvitamin D3) receptor 0.775 0.700 0.744 no

RG081 D08i L06482 Q05343 Retinoid X receptor alpha 0.949 0.611 0.696 no

RG454 D08j M25071 P37826 thyroid hormone receptor ErbA-beta-2, pituitary specific 0.897 0.810 0.674 no

R266 D08k M20133 P15207 Androgen receptor (Testicular feminization) 0.903 0.736 0.710 no

R448 D08l U17254 P22829 immediate early gene transcription factor NGFI-B 2.348 0.791 0.988 no

R099 D08m D38530 P51179 nuclear receptor subfamily 4, group A, member 3 0.737 0.637 0.955 no

R573 D08n X63255 P35439 Glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.253 0.878 0.884 no

R300 D09a M35162 P18506 gamma-aminobutyric acid (GABA-A) receptor, subunit delta 1.614 1.243 1.698 no

R595 D09b X95579 P50572 gamma-aminobutyric acid (GABA-A) receptor, subunit rho 1 1.000 1.166 1.117 no

R729 D09c Y10369 O08620 gamma-aminobutyric acid (GABA) B receptor, 1 1.273 1.001 1.093 no

R716 D09d X17184 P19490 glutamate receptor, ionotropic, AMPA1 (alpha 1) 1.234 1.329 1.260 no

R723 D09e Z11716 Glutamate receptor, ionotropic, kainate 5

P42264 O35420 1.000 1.156 1.000 no

R641 D09f L31622 P12390 cholinergic receptor, nicotinic, beta subunit 2 1.118 0.809 0.800 no

R682 D09g M85035 P19491 glutamate receptor, ionotropic, AMPA2 (alpha 2) 0.805 0.969 0.784 no

R683 D09h M85036 P19492 glutamate receptor, ionotropic, AMPA3 (alpha 3) 0.848 1.071 0.826 no

R684 D09i M85037 P19493 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.696 1.249 0.979 no

R214 D09j L19660 Gastric inhibitory peptide receptor

P42264 O35420 0.967 1.173 0.858 no

R558 D09k X15467 P15432 Gamma-aminobutyric acid receptor beta 2 1.587 1.563 1.007 no

R197 0.806

D09l L08497 P18508 gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2 1.254 0.873 no

RG025 D09m D13212 Q00961 Glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.825 0.943 0.701 no

RG083 0.870

D09n L08490 P18504 gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1 0.838 0.822 no

RG334 D10a X15466 P15431 Gamma-aminobutyric acid receptor beta 1 2.014 1.357 1.457 no

RG360 D10b X57514 P23574 gamma-aminobutyric acid (GABA) A receptor, gamma 10.999 1.105 1.290 no

RG084 0.897

D10c L08491 P23576 gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2 1.340 1.154 no

RG085 D10d L08492 P20236 Gamma-animobutyric acid (GABA) A receptor, alpha 3 1.036 1.082 1.432 no

RG510 D10e X15468 P15433 Gamma-aminobutyric acid receptor beta 3 1.064 0.835 1.148 no

RG195 D10f M81142 P28473 GABA-alpha receptor gamma-3 subunit 1.000 1.000 1.000 no

RG086 1.017

D10g L08493 P28471 gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 4 0.934 0.800 no

RG087 0.986 1.216 0.954 no

D10h L08494 P19969 gamma-aminobutyric acid receptor alpha 5 subunit precursor (GABA(A) receptor; GABRA5)

RG088 0.714

D10i L08495 P30191 gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6 0.902 0.541 no

RG313 D10j U95368 O09028 GABA-A receptor pi subunit 1.009 1.449 0.810 no

RG435 D10k D38494 P47742 gamma-aminobutyric acid (GABA-A) receptor, subunit rho 2 1.102 1.299 0.700 no

RG198 D10l M83561 P22756 Glutamate receptor, ionotropic, kainate 1 0.826 1.338 0.645 no

RG390 0.665 1.206 0.668 no

D10m X74832 P25108 cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)

RG393 D10n X74836 P09660 acetylcholine receptor epsilon 0.789 1.062 0.688 no

RG448 D11a L31620 P09483 Neuronal nicotinic acetylcholine receptor alpha 4 subunit1.120 0.865 0.687 no

RG531 D11b X74833 P25109 Acetylcholine receptor beta 0.998 1.000 1.000 no

R383 D11c M91562 Q00960 Glutamate receptor, ionotropic, N-methyl D-aspartate 2B1.179 1.898 2.055 no

R009 D11d AF001423 O08948 Glutamate receptor, ionotropic, N-methyl D-aspartate 2A0.821 1.079 1.040 no

R652 D11e M18088 P08483 Cholinergic receptor, muscarinic 3 0.723 0.891 1.432 no

R154 D11f J03025 P10980 muscarinic receptor m2 1.000 1.023 1.000 no

RG133 D11g M16409 P08485 Cholinergic receptor, muscarin 4 0.761 0.928 1.134 no

RG151 D11h M22926 P08911 muscarinic acetylcholine receptor M5 0.677 0.698 0.773 no

R031 D11i D00833 Q03238 Glycine receptor, alpha 1 subunit 1.000 1.000 1.000 no

R530 D11j U87305 O08721 transmembrane receptor Unc5H1 1.429 1.043 0.622 no

R531 D11k U87306 O08722 transmembrane receptor Unc5H2 1.373 1.133 0.966 no

RG521 D11l 0.868 1.185 0.999

X61159 P06761 Glycine receptor alpha 2 subunit (glycine receptor, neonatal) no

R013 D11m AF005099 O35764 neuronal pentraxin receptor 1.557 0.820 1.049 no

R025 D11n 0.873

AF018957 Q9QX38 neuropilin; receptor for the axonal chemorepellent semaphorin III 0.968 1.024 no

R727 D12a M96375 Q63373 neurexin 1 0.855 1.337 0.981 no

R728 D12b M96377 Q63376 neurexin 2 1.361 0.967 1.007 no

R190 D12c L06096 Q63269 Inositol 1, 4, 5-triphosphate receptor 3 1.403 1.000 1.000 no

RG374 D12d X61677 P29995 inositol triphosphate receptor type 2 1.036 0.932 0.712 no

R720 D12e X68400 Q64617 protein kinase C-eta 1.138 1.000 1.217 no

R356 D12f M81642 P26824 Thrombin receptor 0.909 0.963 1.027 no

R328 D12g M61099 P23385 Glutamate receptor, metabotropic 1 1.010 0.796 1.005 no

R504 D12h U63288 P70579 metabotropic glutamate receptor 8 1.174 0.873 1.085 no

R047 D12i D13963 P35349 Glutamate receptor, metabotropic 6 0.791 0.926 0.761 no

R387 D12j M92075 P31421 Glutamate receptor, metabotropic 2 0.766 0.738 0.911 no

RG018 D12k D10891 P31424 Glutamate receptor, metabotropic 5 0.869 0.958 0.956 no

RG021 D12l 0.689

D12820 P34987 G protein-coupled receptor 27; gustatory receptor 27 (GUST27) 0.871 0.808 no

RG030 D12m D16817 P35400 mRNA for metabotropic glutamate receptor mGluR7 0.461 0.518 0.386 no

RG216 D12n M90518 P31423 Glutamate receptor, metabotropic 4 1.388 0.721 0.876 no

RG218 D13a M92076 P31422 Glutamate receptor, metabotropic 3 0.849 0.637 0.891 no

RG279 D13b U22830 P49651 P2 purinoreceptor subclass 2Y 1.509 1.000 1.056 no

R122 D13c D63665 Q63371 pyrimidinergic receptor P2Y, G-protein coupled, 6 1.435 1.000 1.497 no

R429 D13d U09402 P41232 purinergic receptor P2Y, G-protein coupled 2 1.150 1.000 1.016 no

R023 D13e AF016297 O35276 neuropilin-2 1.336 1.154 1.297 no

RG173 D13f M55636 P23897 Guanylate cyclase 2C (heat stable enterotoxin receptor)1.629 1.000 1.000 no

R236 D13g L35767 P98166 Very low density lipoprotein receptor 0.968 0.986 1.000 no

R555 D13h LDLR)

X13722 P35952 low-density lipoprotein receptor precursor (LDL receptor;1.403 1.019 1.000 no

R149 D13i J02762 P08290 asialoglycoprotein receptor 2 1.061 1.000 1.000 no

R671 D13j neuropeptide gamma)

M34184 P08857 Tachykinin (substance P, neurokinin A, neuropeptide K, 1.004 0.920 0.960 no

R597 D13k Q Prepronociceptin (neuropeptide nociceptin) (N23K)

X97375 62923 Q64162 1.217 1.133 1.373 no

RG140 D13l M20373 P07808 Neuropeptide Y 1.243 1.314 1.745 no

R258 D13m M16410 P08435 tachykinin 2 1.011 0.935 1.058 no

R396 D13n M94555 P12760 neuromedin U 0.764 0.781 0.880 no

R286 D14a M31176 P24393 gastrin-releasing peptide 1.251 0.975 1.034 no

R412 D14b U03491 Q07258 Transforming growth factor, beta 3 1.000 1.000 1.403 no

R293 D14c M32748 P17777 leukemia inhibitory factor 1.000 1.000 1.263 no

R579 D14d X66539 P16599 Tumor necrosis factor, alpha (cachetin) 1.136 0.984 1.000 no

R209 D14e L15305 Q07731 Glial cell line derived neutrophic factor 1.000 0.945 1.143 no

R326 D14f M60525 P20156 VGF nerve growth factor inducible 1.343 1.053 1.442 no

R606 D14g Z11558 Q63228 glia maturation factor beta 1.100 0.997 1.238 no

R307 D14h M36589 P25427 beta-nerve growth factor precursor (beta-NGF) 0.712 0.829 0.949 no

R468 D14i U37101 P97712 Colony stimulating factor 3 (granulocyte) 0.892 1.006 0.894 no

R689 D14j U00620 P48750 colony stimulating factor 2 (granulocyte-macrophage) 0.705 0.885 0.678 no

R477 D14k U45965 P30348 small inducible cytokine subfamily, member 2 0.807 0.886 0.946 no

R128 D14l D79215 P70492 Fibroblast growth factor 10 1.237 0.837 1.477 no

R191 D14m L06894 P28576 Platelet-derived growth factor A chain 1.651 1.038 1.786 no

R091 D14n D32207 P49745 mRNA for thrombopoietin 1.350 0.962 1.200 no

R251 E01a M13969 P01346 Insulin-like growth factor II (somatomedin A) 0.788 1.085 0.546 no

R318 E01b M55601 P20935 Pleiotrophin (Heparine binding factor, Hbnf, in the mouse)0.901 2.014 2.357 yes no

R649 E01c M15480 P08024 Insulin-like growth factor I 1.194 1.176 0.919 no

R022 E01d factor

AF014827 O35251 c-fos induced growth factor (vascular endothelial growth 0.659 D)1.326 0.661 no

R500 E01e U62326 P30904 macrophage migration inhibitory factor 1.618 1.195 1.919 no

R535 E01f U90448 P97885 CXC chemokine LIX 1.204 1.263 1.508 no

RG015 E01g P29676 P70504

D10763 Erythropoietin 1.000 1.237 1.000 no

RG027 E01h D14839 P36364 Fibroblast growth factor 9 1.000 1.045 1.000 no

RG045 E01i D64085 P48807 fibroblast growth factor FGF-5 0.963 1.339 1.349 no

RG048 E01j D90102 P17945 Hepatocyte growth factor (scatter factor) 1.000 1.327 1.118 no

RG079 1.089 1.044 1.000 no

E01k L05489 Q06175 Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor)

RG149 E01l M22427 P13109 Fibroblast growth factor 2 0.781 0.837 0.944 no

RG168 E01m M34643 P18280 neurotrophin-3 (HDNF/NT-3) 0.643 1.115 0.633 no

RG182 E01n M60921 P27049 Early induced gene, B-cell translocation gene 2 0.824 0.753 0.733 no

RG238 E02a S69323 P34131 Neurotrophin 5 (neurotrophin 4/5) 0.987 1.000 0.988 no

RG243 E02b S77492 P49002 Bone morphogenetic protein 3 0.919 0.997 0.920 no

RG342 E02c X52498 P17246 transforming growth factor, beta-1 1.139 1.171 0.887 no

RG353 E02d X55183 P24338 amphiregulin 0.627 0.807 0.564 no

RG357 E02e X56551 P13109 fibroblast growth factor 7 3.448 0.751 3.215 no

RG434 E02f D21095 Q10747 cytokine-induced neutrophil chemoattractant-2 1.154 0.858 1.555 no

RG509 E02g X14232 P10935 Fibroblast growth factor 1 (heparin binding) 0.895 0.888 0.896 no

RG538 E02h Z22607 Q06826 Bone morphogenetic protein 4 1.040 1.119 0.929 no

RG539 E02i Z25868 P49001 bone morphogenetic protein 2 0.789 0.793 0.985 no

R291 E02j M32167 P16612 vascular endothelial growth factor 0.797 1.185 1.466 no

R696 0.819 1.073

E02k U22414 P50229 Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3) 0.821 no

R534 E02l U90447 P97884 small inducible cytokine subfamily A20 0.918 0.919 0.919 no

R411 0.989 (APO-1) 0.989 no

E02m U03470 P36940 Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis 1.071 antigen ligand 1) (Fas antigen ligand)

R274 E02n M25297 P13205 Brain natriuretic factor 0.889 1.140 0.890 no

R294 E03a M32754 P17490 Inhibin, alpha 1.000 1.031 1.000 no

R305 E03b M36317 P01150 Thyrotropin releasing hormone 1.000 1.043 1.000 no

R308 E03c M36804 P18427 Follicle - stimulating hormone subunit beta 1.086 1.000 1.150 no

R316 E03d M55269 P21702 placental lactogen 1 1.438 1.078 1.000 no

R250 E03e M13750 P09320 Prolactin-like protein A 2.112 1.055 1.703 no

R276 E03f M25890 P01167 Somatostatin 1.241 0.874 0.913 no

R695 E03g U10156 P09916 growth hormone releasing hormone 0.869 1.010 1.965 no

R455 E03h U25651 P47858 phosphofructokinase, muscle 1.150 0.996 0.862 no

R697 E03i U25684 P97563 thymosin beta-like protein 0.637 0.551 0.551 no

R501 E03j U62779 P01244 gonadotropin-releasing hormone receptor 1.024 9.043 1.000 no

RG050 E03k D90219 P55207 natriuretic peptide precursor C 0.647 0.856 0.507 no

RG135 E03l M17523 P10631 peptide YY precursor (PYY) 0.933 0.921 0.934 no

RG157 E03m M29712 P14200 Pro-melanin-concentrating hormone 0.852 0.917 0.754 no

RG314 E03n V01252 glycoprotein hormones, alpha subunit

P11962 P70516 1.000 1.330 1.000 no

RG316 0.689

E04a X01118 P01161 Natriuretic peptide precursor A, (pronatriodilatin, also Anf, Pnd) 1.265 1.022 no

RG317 E04b X01454 P04652 Thyroid stimulating hormone, beta subunit 0.825 0.979 1.316 no

RG318 E04c X02341 P01283 vasoactive intestinal polypeptide 0.819 1.114 0.890 no

RG428 P01237 P70520

E04d AF022935 Prolactin 0.819 1.234 0.821 no

RG450 E04e M12579 P07490 Gonadotropin releasing hormone 0.634 0.875 0.637 no

RG453 E04f M54987 P01143 corticotropin releasing hormone 1.626 1.204 1.078 no

RG459 E04g M37482 P18331 inhibin beta-A 0.924 1.182 0.955 no

RG461 E04h M38653 P04563 Gastrin 0.993 1.257 0.832 no

RG502 E04i V01228 P01257 Calcitonin/calcitonin-related polypeptide, alpha 1.961 1.364 1.575 no

RG315 E04j X00336 P05011 interferon, alpha 1 0.848 0.745 0.741 no

R020 E04k AF010466 P01581 Interferon gamma 1.000 1.000 1.259 no

R525 E04l U77776 interleukin 18

P97636 P97637 0.943 1.065 0.944 no

RG009 E04m D00403 P16598 Interleukin 1 alpha 0.951 0.957 0.952 no

RG230 E04n M98820 Q63264 Interleukin 1 beta 0.670 0.786 0.673 no

R269 E05a M22899 P17108 interleukin 2 0.824 1.295 1.358 no

RG154 E05b M26744 P20607 Interleukin 6 (interferon, beta 2) 1.023 1.065 1.199 no

R018 E05c AF010464 P56478 Interleukin 7 0.768 0.790 1.167 no

R181 E05d L02926 Interleukin 10

P29456 Q63263 0.837 0.833 0.867 no

RG114 E05e L26913 P42203 interleukin 13 0.793 0.877 1.023 no

R514 P Interleukin 15

E05f U69272 97604 O54847 1.910 1.318 1.106 no

R616 E05g J04486 P12843 Insulin-like growth factor binding protein 2 0.983 1.403 1.253 no

R112 E05h D49653 P50596 Obesity (murine homolog, leptin) 0.668 0.790 0.672 no

R685 E05i M89791 P21743 Insulin-like growth factor binding protein 1 0.533 0.839 0.397 no

R289 E05j M31837 P15473 Insulin-like growth factor-binding protein (IGF-BP3) 0.937 0.972 1.534 no

R340 E05k M64711 P22388 Endothelin 1 1.026 1.000 1.000 no

R344 E05l M69055 P35572 Insulin-like growth factor binding protein 6 0.707 0.771 0.775 no

RG183 E05m M62781 P24594 Insulin-like growth factor-binding protein 5 0.778 0.809 0.729 no

RG259 E05n U10071 P49192 cocaine and amphetamine regulated transcript 0.577 0.871 0.768 no

RG363 E06a X58023 P24388 corticotropin releasing hormone binding protein 0.968 1.308 0.817 no

RG506 E06b X06832 P10354 Chromogranin A, parathyroid secretory protein 1 1.249 2.105 2.227 yes yes

R228 E06c L27867 Q63366 Neurexophilin 1 0.951 0.965 1.160 no

R262 E06d M18416 P08154 Early growth response 1 3.323 0.628 1.018 no

R630 E06e L08831 Q06145 gastric inhibitory polypeptide 0.608 0.719 0.443 no

R317 0.867 subunit

E06f M55431 Q00918 transforming growth factor-beta (TGF-beta) masking protein large1.011 0.861 no

R377 E06g M88469 P35446 f-spondin 1.179 1.389 1.658 no

RG250 E06h U02983 P47868 secretogranin III 1.176 0.968 0.972 no

R114 P29354 growth

E06i D49846 Q63057 Q14450 factor receptor bound protein 2 0.958 0.808 1.027 no

R384 E06j M91589 P29066 Arrestin, beta 1 0.962 0.969 0.981 no

R385 E06k M91590 P29067 Arrestin, beta 2 1.090 0.848 0.857 no

RG251 E06l U03628 P36576 arrestin 3, retinal (X-arrestin) 0.790 0.703 0.715 no

RG282 E06m U26595 Q62786 prostaglandin F2 receptor negative regulator 0.726 0.722 0.801 no

RG305 1.071 2 (S. 0.846

E06n U60882 Q63009 heterogeneous nuclear ribonucleoproteins methyltransferase-like1.084 cerevisiae) no

RG482 E07a U03629 P36577 arrestin D + guanine aminohydrolase (GAH) 0.791 0.937 1.345 no

R465 E07b U34841 Q62833 G protein-coupled receptor kinase 5 0.849 1.387 1.080 no

R569 1.277

E07c X58631 P32577 c-src-kinase (CSK) & negative regulator; tyrosine-protein kinase 0.872 1.050 no

R680 P Hemopoietic cell tyrosine kinase

E07d M83666 50545 Q64647 0.975 0.894 0.975 no

R452 E07e U21684 Q64725 Spleen tyrosine kinase 1.057 0.757 0.652 no

R611 Q07014 Q63320 protein non-receptor kinase

E07f AF000300 lyn 1.055 1.000 1.000 no

R568 E07g X57986 P27791 Protein kinase, cAMP-dependent, catalytic, alpha 1.073 0.788 0.850 no

R230 1.041 0.936 0.855

E07h L29281 Q63184 Protein kinase, interferon-inducible double stranded RNA dependent no

R028 E07i AJ000556 O35803 Janus kinase 1 1.474 1.242 0.960 no

R441 E07j U13396 Q62689 Janus kinase 2 (a protein tyrosine kinase) 1.183 1.000 1.000 no

R079 E07k D28508 P49186 Janus kinase 3, protein-tyrosine kinase 1.235 1.000 1.000 no

R637 E07l L27129 P49185 mitogen-activated protein kinase 8 1.445 1.305 1.464 no

R635 E07m L27112 P49186 stress activated protein kinase alpha II 0.798 0.906 0.594 no

R636 E07n L27128 P49187 Stress activated protein kinase beta 1.073 1.000 1.000 no

R675 E08a M61177 P21708 mitogen activated protein kinase 3 1.176 1.047 0.841 no

R676 E08b M64300 P27703 mitogen activated protein kinase 1 0.905 1.433 0.815 yes no

R339 E08c M64301 P27704 mitogen-activated protein kinase 6 1.030 1.568 1.096 no

R088 E08d D31873 P53669 LIM-domain containing, protein kinase 1.791 0.911 0.905 no

R089 E08e D31874 P53670 LIM motif-containing protein kinase 2 2.079 0.921 1.326 no

R519 E08f U73142 P70618 p38 mitogen activated protein kinase 1.199 1.102 0.875 no

R724 E08g Z16415 Q01986 mitogen activated protein kinase kinase 2 0.731 1.366 0.707 no

R613 E08h D14592 P36506 mitogen activated protein kinase kinase 2 1.206 1.157 1.032 no

R470 E08i U37462 Q62862 mitogen activated protein kinase kinase 5 1.012 1.102 0.826 no

R713 E08j X07286 P05696 Protein kinase C, alpha 1.000 1.661 1.236 no

R657 E08k M19007 P04410 Protein kinase C beta 0.908 1.500 1.460 no

R653 E08l M18330 P09215 protein kinase C, delta 1.298 1.132 1.488 no

R027 O35346 Q62900

E08m AF020777 Protein tyrosine kinase 1.000 1.212 1.388 no

R654 E08n M18331 P09216 protein kinase C, epsilon 1.156 1.646 1.880 no

R714 E09a X07287 P05697 Protein kinase C, type I (gamma type) 1.683 1.193 0.991 no

R655 E09b M18332 P09217 protein kinase C, zeta 1.244 1.327 1.451 no

R075 E09c D26180 Q63433 protein kinase C-like 1 1.527 1.014 1.373 no

R334 E09d M63334 P13234 Calmodulin-dependent protein kinase IV 1.686 1.000 2.208 no

R111 P cell

E09e D45854 70600 Q63201 adhesion kinase beta 1.154 0.870 1.094 no

R374 E09f M87854 P26817 adrenergic receptor kinase, beta 1 1.014 0.686 0.682 no

R375 1.000 1.000 1.031 no

E09g M87855 P26819 Adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase)

RG097 E09h L13408 P15791 Ca++/calmodulin-dependent protein kinase II, delta subunit 1.196 0.910 1.136 no

RG190 E09i M73808 P31325 phosphorylase kinase, gamma 2 (testis) 1.037 0.804 0.934 no

RG217 Q insulin receptor-related receptor

E09j M90661 64716 Q63146 0.668 0.583 0.332 no

RG220 Q64649 phosphorylase B kinase alpha subunit

E09k M92919 Q64650 Q64651 1.000 1.000 1.000 no

RG277 E09l U22296 Q62761 casein kinase 1 gamma 1 1.000 1.000 1.019 no

RG327 E09m X07320 P13286 Phosphorylase kinase, gamma 1 1.000 1.000 1.096 no

RG437 E09n J02942 P11275 Ca2+/calmodulin-dependent protein kinase II alpha 1.298 0.806 0.878 yes no

RG494 E10a U63971 Q63651 rhodopsin kinase 0.961 1.108 0.580 no

R210 E10b L15618 P19139 casein kinase II, alpha 1 polypeptide 1.722 1.236 1.898 no

R644 E10c L34542 P41243 megakaryocyte-associated tyrosine kinase 0.989 0.589 0.556 no

R402 E10d M99169 Q63531 S6 protein kinase (Rsk-1) 0.615 0.938 0.618 no

R562 E10e X53427 P18265 glycogen synthase kinase 3 alpha 0.626 0.875 0.603 no

R256 E10f M16112 P08413 Ca++/calmodulin-dependent protein kinase II, beta subunit 0.974 1.013 0.880 yes no

R726 E10g L24907 calcium/calmodulin-dependent protein kinase I

Q63450 Q63084 0.961 1.132 0.906 no

R175 E10h L01624 Q06226 serum/glucocorticoid regulated kinase 1.940 0.838 0.823 no

R074 E10i D26178 Q62726 heart serine-threonine protein kinase 0.896 0.935 0.786 no

R193 E10j L07578 Q06486 casein kinase I delta 0.961 1.121 0.858 no

R241 E10k L42810 Q64572 calcium/calmodulin-dependent protein kinase kinase 1, alpha0.849 0.963 0.926 no

R301 E10l M35862 P20793 Male germ cell-associated kinase 1.000 1.297 1.000 no

R454 P p21

E10m U23443 35465 Q62934 (CDKN1A)-activated kinase 1 0.786 1.341 1.086 no

R006 E10n AB005540 O35831 serine/threonine kinase PCTAIRE2 (PCTK2) 0.612 1.170 0.957 no

R007 E11a AB005541 O35832 serine/threonine kinase PCTAIRE3 (PCTK3) 1.357 1.318 1.543 no

R217 E11b L22294 Q63065 pyruvate dehydrogenase kinase, isoenzyme 1 1.593 1.011 1.963 no

R458 0.920 1.101 1.908 no

E11c U28356 P49445 HEP; LC-PTP protein-tyrosine phosphatase; hematopoietic protein-tyrosine phosphatase (HEPTP)

R395 E11d M94454 Q63562 itogen-activated protein kinase kinase kinase 8 0.878 0.920 1.610 no

R203 E11e L11007 P35426 cyclin-dependent kinase 4 0.968 1.067 0.944 no

R177 E11f L02121 Q03114 cyclin-dependent kinase 5 1.044 0.955 0.971 no

R571 E11g X60767 P39951 Cell division cycle control protein 2 0.859 0.969 0.809 no

R087 E11h D31838 Q63802 wee1 tyrosine kinase 0.910 1.131 1.282 no

R466 E11i U36444 Q63686 PCTAIRE-1 protein kinase, alternatively spliced 0.783 0.809 0.473 no

R598 1.062 1.010

E11j X97568 P70507 G protein-coupled receptor kinase 2, groucho gene related (Drosophila) 1.680 no

R427 P SH-PTP2 protein tyrosine phosphatase, non-receptor type 11 1.265 1.584 no

E11k U09307 41499 Q62626 0.925

R270 0.837 1.036 1.262 no

E11l M23591 P11082 Protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform

R096 E11m D38260 P36877 BRbeta B-regulatory subunit of protein phosphatase 2A 0.809 1.225 1.120 no

R227 Q63739 protein

E11n L27843 O09154 O09097 tyrosine phosphatase 4a1 0.737 1.058 1.205 no

RG065 0.603 isoform

E12a J04503 P20650 Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha 0.944 0.510 no

RG162 E12b M31809 P20651 Calcineurin subunit A beta 0.806 1.090 0.846 no

RG197 P protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform no

E12c M83298 36876 P36878 0.614 1.053 0.574

RG232 E12d S49400 P35234 protein tyrosine phosphatase, non-receptor type 5 1.094 1.058 0.593 no

RG273 Q protein tyrosine phosphatase 2E

E12e U18293 62728 Q62732 0.608 0.823 0.611 no

RG456 E12f M33962 P20417 protein tyrosine phosphatase, non-receptor type 1 1.197 1.054 1.002 no

RG480 1.051 0.916

E12g S90449 P35815 Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform 0.599 yes no

RG520 E12h X58828 P35233 protein tyrosine phosphatase, non-receptor type 2 0.887 1.303 0.888 no

R176 E12i L01702 Q03348 Protein tyrosine phosphatase, receptor type, A 0.907 1.602 1.414 no

R238 E12j L36884 Q64612 Osteotesticular phosphatase 1.061 1.046 1.000 no

R127 E12k D64050 O08617 protein tyrosine phosphatase, receptor type, R 1.490 0.888 1.042 no

RG337 0.874 1.181 0.777 no

E12l X16043 P13353 Protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

R391 E12m M94043 Q63483 Rab-related GTP-binding protein 1.218 0.972 0.926 no

R631 0.762 1.107 0.706 no

E12n L19698 P05810 -ral simian leukemia viral oncogene homolog A (ras related)

R632 0.858 1.252 1.280 no

E13a L19699 P36860 v-ral simian leukemia viral oncogene homolog B (ras related)

R237 E13b L35921 P43426 G-protein gamma 8 subunit 0.823 1.066 1.133 no

R698 E13c U34958 P54311 Guanine nucleotide-binding protein beta 1 0.906 1.176 1.186 no

R699 1.090 0.962 0.745

E13d U34959 P54313 transducin beta-2 subunit; GTP-binding protein G(i)/G(s)/G(t) beta subunit 2 (GNB2) no

R638 E13e L29090 P52287 G protein beta-subunit gene 0.790 0.471 0.609 no

R143 P Muscle and microspikes RAS

E13f D89863 97538 O09021 1.522 1.303 1.150 no

R437 E13g U12187 P55043 Ras-related associated with diabetes 1.608 1.000 1.228 no

R659 1.359

E13h M20713 P08753 Guanine nucleotide binding, protein, alpha inhibiting polypeptide 30.941 0.979 no

R651 E13i M17528 P04897 GTP-binding protein (G-alpha-i2) 1.214 1.244 1.245 no

RG005 P54314 O35354

E13j AF001953 guanine nucleotide binding protein beta 5 1.092 1.182 1.021 no

RG107 subunit

E13k L23219 P43425 guanine nucleotide binding protein (G protein), gamma 71.192 1.000 1.000 no

RG136 E13l M17526 P04900 guanine nucleotide binding protein, alpha o 1.172 0.989 0.885 no

RG137 E13m M17527 P10824 Guanine nucleotide binding protein, alpha inhibiting 1 0.934 0.942 0.906 no

RG400 E13n X78604 P51646 ADP-ribosylation factor-like 5 1.219 0.990 1.054 no

RG440 E14a J03773 P19627 Guanine nucleotide binding protein, alpha 1.039 0.852 1.225 no

RG533 E14b X78603 Q63055 ADP-ribosylation factor related protein 1 0.754 0.699 1.000 no

R261 P Guanine nucleotide-binding protein G-s, alpha subunit 0.985 1.082 1.170 no

E14c M17525 04894 P08755

R153 E14d J02999 P05712 RAB2, member RAS oncogene family 0.841 1.101 0.706 no

R712 E14e X06889 P05713 Ras-related small GTP binding protein 3A 1.238 0.825 0.638 no

R550 E14f X06890 P05714 Ras-related small GTP binding protein 4 2.050 1.660 1.738 no

R722 E14g Y14019 Q63941 Rab3B protein 1.204 0.892 0.994 no

R348 E14h M75153 P24410 RAB11a, member RAS oncogene family 1.018 1.024 1.306 no

RG200 E14i M83676 P35284 RAB12, member RAS oncogene family 0.855 0.795 0.592 yes yes

RG203 E14j M83679 P35289 rab15, ras related GTPase 1.063 1.270 1.033 no

RG204 E14k M83680 P35287 GTPase Rab14 0.676 1.546 1.130 no

RG205 E14l M83681 P35291 RAB3D, member RAS oncogene family 1.126 0.926 0.834 no

RG227 P G

E14m M95780 30670 Q61015protein gamma-5 subunit 1.000 1.595 1.103 no

RG274 E14n U18771 P51156 RAB26, member RAS oncogene family 0.794 1.052 1.342 no

RG401 F01a X78605 P51146 ras-related GTP-binding protein 4b 0.999 0.955 0.579 no

R580 0.772 1.810

F01b X67241 P28818 Ras-GRF (p140); sos; guanine nucleotide release/exchange factor (GNRP)0.501 yes yes

R140 F01c D85760 Q63210 guanine nucleotide binding protein (G protein) alpha 12 0.916 0.827 0.459 yes no

R090 F01d D31962 Q63744 rho GTPase activating protein 7 1.250 1.054 0.931 no

R195 F01e L07925 Q03386 ral guanine nucleotide dissociation stimulator 1.291 1.089 0.835 no

R457 F01f U27767 P49799 regulator of G-protein signaling 4 0.775 0.852 0.657 yes no

R528 F01g U80076 P97680 ras inhibitor 1.597 1.068 0.773 no

R160 F01h J03806 P10686 Phospholipase C, gamma 1 1.484 1.234 1.047 no

R618 F01i J05155 P24135 phospholipase C, gamma 2 1.000 1.000 1.000 no

R268 F01j M20637 P10688 Phospholipase C-delta1 1.332 0.993 0.852 no

R436 F01k U11681 P42346 rapamycin and FKBP12 target-1 protein 0.844 0.752 0.699 no

R117 F01l D50455 Q63693 phospholipase C, delta 4 1.186 0.891 0.949 no

R488 F01m U55192 P97573 Inositol polyphosphate-5-phosphatase 1.028 1.000 1.000 no

R711 F01n U96920 O35825 inositol polyphosphate-4-phosphatase, type II, 105kD 1.000 1.000 1.000 no

RG252 F02a U03763 P51433 phospholipase A2, group V 0.782 1.452 0.860 no

RG255 F02b U07798 P39878 phospholipase A2, group IIC 0.724 0.880 0.965 no

RG270 1.026

F02c U17035 P48973 small inducible cytokine B subfamily (Cys-X-Cys), member 10 1.353 0.837 no

RG290 F02d U38665 Inositol 1,4,5-triphosphate receptor type 1 0.920 1.080 0.831 no

RG387 F02e X74227 P42335 Inositol 1,4,5-trisphosphate 3-kinase B 1.007 0.954 0.673 no

R137 F02f D84667 O08561 phosphatidylinositol 4-kinase 1.199 0.830 0.742 no

R131 F02g D83538 O08662 phosphatidylinositol 4-kinase 1.291 1.753 1.519 yes no

R404 F02h M99567 Q99JE6 phospholipase C, beta 3 1.292 0.999 0.945 no

R267 F02i M20636 P10687 phospholipase C beta 1 (PLC beta 1); PLC-I; PLC-154 0.774 0.735 0.961 no

R485 F02j U51898 P97570 phospholipase A2, group VI 0.820 0.803 0.805 no

R634 F02k L27057 P54748 Phosphodiesterase 4A 1.088 0.955 0.897 no

R608 F02l Z22867 Q63085 phosphodiesterase 3B, cGMP-inhibited 0.707 0.707 0.709 no

R693 0.872 1.034 0.851 no

F02m U09457 P14270 Phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3)

R622 F02n L01115 Q03343 Adenylyl cyclase 6 1.215 1.000 1.122 no

RG194 F03a M80633 P26770 Adenylyl cyclase 4 0.821 1.461 0.823 no

RG115 F03b L26986 P40146 Adenylyl cyclase 8 0.627 1.122 0.708 no

RG125 F03c L37203 P51839 guanylate cyclase 2d 0.880 1.321 0.881 no

R663 F03d M25347 P14644 DPDE1; cAMP-dependent 3',5'-cyclic phosphodiesterase 4C 0.979 1.099 0.823 no

R617 1.375 1.429 0.745 no

F03e J04563 P14646 Phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4)

R354 F03f M80550 P26769 adenylyl cyclase 2 0.882 0.869 0.751 yes no

R315 F03g M55075 P21932 type III adenylyl cyclase 1.459 0.965 0.717 no

R687 F03h M96159 Q04400 adenylate cyclase 5 0.927 0.926 0.445 no

RG013 P calcineurin B-like protein

F03i D10393 28470 Q63878 1.000 1.243 1.000 no

RG161 F03j M31178 P07171 cerebellar Ca-binding protein, spot 35 protein 1.166 1.134 1.219 no

RG383 F03k X66974 P47728 calbindin 2 1.134 1.265 1.000 no

R185 F03l L03554 protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)

P06705 P15117 0.784 1.479 0.793 no

R226 F03m L27421 P36610 frequenin homolog (Drosophila) 1.182 1.069 0.730 no

R032 F03n D10666 Neural visinin-like protein 1

P28677 P29103 0.909 0.852 0.764 yes yes

R043 F04a D13125 P35332 neural visinin-like Ca2+-binding protein type 2 1.220 0.964 0.825 yes yes

R044 F04b D13126 P35333 neural visinin-like Ca2+-binding protein type 3 0.861 0.717 0.557 yes yes

RG155 P Calcineurin subunit A alpha

F04c M29275 20652 P12816 0.871 2.174 1.658 yes yes

R248 F04d M12492 P12369 cAMP-dependent protein kinase type II-beta regulatory chain 0.950 1.078 0.732 no

R064 P35215 Tyrosine 0.921 2.019 1.283 yes no

F04e D17615 P70197 P97286 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

R179 F04f L02615 P27776 protein kinase inhibitor, alpha 1.237 1.456 0.853 no

R337 1.216 0.939 0.940 no

F04g M64092 P27775 cAMP-dependent protein kinase (catalytic subunit binding) inhibtor 2

RG233 F04h S55305 P35214 14-3-3 protein gamma-subtype 1.025 1.220 0.729 no

R060 F04i D17445 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

P11576 P70198 0.856 1.247 0.736 no

R063 0.773 1.116 0.645 no

F04j D17614 P35216 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

R681 P42655 tyrosine 0.819 1.359 epsilon no

F04k M84416 P29360 Q63631 3-monooxygenase/tryptophan 5-monooxygenase activatioprotein, 0.841 polypeptide

R422 F04l U07560 P52796 Ephrin B1 0.802 0.964 0.803 no

R508 1.131

F04m U66478 P97588 MAD (mothers against decapentaplegic, Drosophila) homolog 1 1.062 1.000 no

R509 O MAD 1.089

F04n U66479 09144 O09064 (mothers against decapentaplegic, Drosophila) homolog 3 1.000 1.000 no

R082 F05a D29766 Q63766 v-crk-associated tyrosine kinase substrate 0.751 1.177 0.754 no

R126 D64045 Phosphoinositide 3-kinase p85

F05b Q63787 Q63790 P70544 O55085 0.761 0.864 0.763 no

R325 F05c M59859 P30009 Myristoylated alanine-rich protein kinase C substrate 0.858 0.799 0.859 no

R004 O88777 presenilin-2

F05d AB004454 O35546 O08947 0.957 0.654 0.469 no

R129 F05e D82363 presenilin 1

P97887 P97529 1.120 0.727 0.594 no

R259 F05f M16736 P07936 brain abundant, membrane attached signal protein 2 1.120 2.472 2.529 yes no

R138 P Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1)

F05g D85183 97710 O08951 1.172 0.752 0.555 yes no

R048 F05h D13985 Q04753 chloride channel, nucleotide-sensitive, 1A 1.082 0.910 0.756 no

R178 F05i L02529 Q08463 Drosophila polarity gene (frizzled) homologue 0.933 0.784 0.835 no

R476 Q kinase substrate HASPP28

F05j U41744 62785 Q62890 0.913 1.499 1.180 no

RG091 F05k L12380 ADP-ribosylation factor 1

P32889 P10947 0.894 0.488 0.369 no

RG444 F05l L12381 ADP-ribosylation factor 2

P16500 P10947 0.872 1.014 0.568 no

RG092 F05m L12382 P16587 ADP-ribosylation factor 3 1.011 0.753 0.740 no

RG093 F05n L12383 P36403 ADP-ribosylation factor 4 0.915 0.632 0.671 no

RG094 F06a L12384 P26437 ADP-ribosylation factor 5 0.873 0.781 0.523 yes no

RG095 F06b L12385 P26438 ADP-ribosylation factor 6 0.627 0.977 0.930 no

RG479 F06c S83440 P35213 14-3-3 protein beta-subtype 1.012 2.009 1.265 no

RG491 F06d U48245 Q62918 nel-like 2 homolog (chicken) 1.113 1.389 0.869 no

RG492 F06e U48246 Q62919 protein kinase C-binding protein NELL1 1.851 1.159 1.520 no

R397 F06f M94721 P81128 GAP-associated protein (p190). 1.055 1.356 1.769 no

R449 F06g U17901 P54319 phospholipase A2, activating protein 1.185 1.000 1.091 no

RG370 F06h X59949 P29476 Nitric oxide synthase 1 (neuronal) 1.000 1.000 1.720 no

R503 F06i U62897 O35850 Carboxypeptidase D precursor 0.760 0.724 1.055 no

R392 F06j M94056 P31430 dipeptidase 1 1.227 1.000 1.128 no

R484 F06k U50194 Q64560 tripeptidylpeptidase II 0.768 0.791 0.961 no

R336 1.011 1.103 1.098

F06l M63901 P27682 Secretory granule neuroendocrine, protein 1 (7B2 protein) yes no

R620 F06m K02298 P07338 Chymotrypsin B 0.787 0.834 1.271 no

R629 F06n V01233 P00774 Elastase 2, pancreatic 1.000 1.000 1.000 no

R621 F07a L00130 P00763 Pancreatic trypsin II 1.000 1.000 1.129 no

R678 F07b M76705 P28840 Protein convertase subtilisin / kexin, type I 0.866 0.917 1.115 no

R575 F07c X63434 P29598 Urinary plasminogen activator, urokinase 1.000 1.053 1.000 no

R349 F07d M76426 P46101 dipeptidylpeptidase 6 0.880 1.180 0.829 no

R704 F07e U67907 P97592 mast cell protease 4 0.913 0.790 0.775 no

R510 F07f U67909 mast

P50343 P97593 cell protease 6 1.148 1.444 1.000 no

R705 F07g U67911 P97594 mast cell protease 8 1.069 1.298 1.000 no

R271 F07h M23697 P19637 Plasminogen activator, tissue 1.699 1.689 1.026 no

RG058 F07i J02997 P14740 Dipeptidyl peptidase 4 1.000 1.000 1.000 no

RG192 F07j M76706 P28841 Proprotein convertase subtilisin/kexin type 2 1.341 1.005 0.911 no

RG196 F07k M81397 P18292 coagulation factor II 0.833 0.682 0.383 no

RG336 F07l X15679 P12788 trypsinogen 4 0.327 0.951 0.329 no

R187 F07m L05175 Q03238 lymphoctye Met-ase 1 1.341 0.846 0.927 no

R706 F07n U67915 P09650 mast cell protease 1 1.000 1.000 1.000 no

R511 F08a U67910 P27435 mast cell protease 7 1.000 1.216 1.000 no

R098 F08b D38495 P50339 Chymase 1, mast cell 1.602 1.000 1.000 no

RG351 F08c X54467 P24268 cathepsin D 1.564 0.948 0.895 no

R152 F08d J02941 P08424 Renin 1.018 1.045 0.800 no

R413 0.957

F08e U03734 P47820 Angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1) 1.165 0.795 no

R219 F08f L24374 P50280 Matrix metalloproteinase 7 (matrilysin) 1.000 1.005 1.014 no

R628 F08g M31602 P15087 Carboxypeptidase E 0.982 1.752 1.047 no

R498 O aminopeptidase B

F08h U61696 09175 P97530 1.193 0.971 0.747 no

R139 F08i D85509 O35548 matrix metalloproteinase 16 1.309 1.019 1.000 no

R278 F08j M26710 P15684 alanyl (membrane) aminopeptidase 1.402 1.000 1.000 no

R379 F08k M88601 P28826 Meprin 1 beta 1.007 0.395 0.379 no

R081 F08l D29683 P42893 Endothelin-converting enzyme 1 1.162 0.855 0.681 no

RG319 F08m X02601 P03957 matrix metalloproteinase 3 1.656 1.000 1.000 no

R478 F08n U46034 P97568 Matrix metalloproteinase 11 (stromelysin 3) 1.544 1.000 1.146 no

R506 F09a U65656 P97581 gelatinase A 0.738 0.809 0.981 no

R463 F09b U32990 Q11009 aminopeptidase Vp165 0.683 0.777 1.247 no

R144 F09c D90404 Cathepsin C (dipeptidyl peptidase I)

P80067 P80068 0.769 0.759 1.087 no

R017 F09d AF010306 O35186 cathepsin K 0.837 0.980 1.036 no

R306 F09e M36320 P00786 Cathepsin H 1.055 1.085 1.244 no

R182 F09f L03201 Q02765 cathepsin S 1.167 1.116 1.744 no

RG416 F09g Y00697 P07154 Cathepsin L 0.686 1.580 1.128 no

RG534 F09h X82396 P00787 cathepsin B 0.769 0.753 0.813 no

R483 0.930 0.916 1.168

F09i U49930 P55213 Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease) no

R443 F09j U14647 P43527 Interleukin 1beta converting enzyme 1.000 1.000 1.000 no

R283 F09k M29859 P18420 proteasome (prosome, macropain) subunit, alpha type 10.852 0.930 0.826 no

R151 F09l J02897 P17220 proteasome (prosome, macropain) subunit, alpha type 21.081 1.386 1.301 no

R324 F09m M58593 P18422 proteasome (prosome, macropain) subunit, alpha type 31.463 1.237 1.642 no

R086 F09n D30804 P48004 proteasome (prosome, macropain) subunit, alpha type 71.308 0.828 1.126 no

R035 F10a D10755 P34062 proteasome (prosome, macropain) subunit, alpha type 60.822 1.336 0.980 no

R036 F10b D10756 P34064 proteasome (prosome, macropain) subunit, alpha type 50.758 0.617 0.597 no

R109 F10c D45249 Q63797 protease (prosome, macropain) 28 subunit, alpha 0.926 0.750 0.716 no

R068 F10d D21800 P40112 proteasome (prosome, macropain) subunit, beta type, 3 0.986 0.792 0.762 no

R067 F10e D21799 P40307 proteasome (prosome, macropain) subunit, beta type, 2 0.861 1.082 0.606 no

RG001 F10f P52915 for proteasomal ATPase (SUG1)

AB000491 P52916 O35051 0.932 1.071 0.677 no

RG041 F10g D50694 Q63347 Proteasome (prosome, macropain) 26S subunit, ATPase 0.780 1.216 0.749 no

RG042 F10h D50695 Q63570 proteasome (prosome, macropain) 26S subunit, ATPase, 4 1.028 0.722 0.523 no

RG043 F10i D50696 P49014 protease (prosome, macropain) 26S subunit, ATPase 1 0.927 1.296 0.921 no

RG099 F10j P34067 proteasome (prosome, macropain) subunit, beta type, 4 0.699 0.760 0.515 no

L17127 P97719 P28071

RG309 F10k Q proteasome (prosome, macropain) 26S subunit, ATPase1.395 1.323 1.347 no

U77918 63569 P97638 3

RG347 F10l X52783 P18421 proteasome (prosome, macropain) subunit, beta type 1 0.890 0.711 0.547 no

RG356 F10m X55986 P21670 proteasome (prosome, macropain) subunit, alpha type 41.081 1.142 1.000 no

R642 F10n L31883 P30120 tissue inhibitor of metalloproteinase 1 1.220 1.000 1.455 no

R643 F11a L31884 P30121 tissue inhibitor of metalloproteinase 2 1.140 1.374 0.935 no

R292 F11b 0.904 0.924 0.905 member 1

M32247 P17475 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin),no

R665 F11c P Serine protease inhibitor, kanzal type 1/ Trypsin inhibitor-like protein, pancreatic

M27882 09655 P13072 1.000 1.000 1.000 no

R456 F11d U27201 P48032 Tissue inhibitor of metalloproteinase 3 1.007 1.041 0.621 no

R475 F11e U40260 Q64361 latexin 0.991 1.427 1.088 no

R156 F11f J03552 P14046 alpha(1)-inhibitor 3, variant I 0.689 0.689 0.691 no

R272 F11g 0.840 1.044 0.842 no

M24067 P20961 serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

RG358 F11h X56729 P27321 Calpastatin 1.085 1.012 0.850 no

RG526 F11i X64563 P29524 plasminogen activator inhibitor 2 type A 0.954 0.820 0.561 no

R542 F11j U94710 O08628 procollagen C-proteinase enhancer protein 0.913 0.874 0.799 no

R329 F11k M61142 P24155 metalloendopeptidase 0.805 0.628 0.465 no

R225 F11l receptor, type 0.419 no

L26525 Q63474 Discoidin domain receptor (neurotrophic tyrosine kinase,0.857 0.625 4 (cell adhesion kinase))

R554 F11m X13412 P09760 Flk tyrosine-protein kinase; fps/fes-related 0.632 0.568 0.560 no

RG476 F11n S76466 P80202 serine/threonine kinase receptor, type I 1.129 0.864 0.641 no

R204 F12a L11586 Q64604 protein tyrosine phosphatase, receptor-type, F 1.021 1.066 1.367 no

RG498 F12b U73458 Q63475 protein tyrosine phosphatase, receptor-type, N polypeptide 2 1.000 1.000 1.262 no

R213 F12c L19181 Q64621 Protein tyrosine phosphatase, receptor type, D 1.224 0.907 0.823 no

R095 F12d D38222 Tyrosine phosphatase-like protein; negative regulator of 1.472 0.853 0.846 noRAT PHEOCHROMOCYTOMA-DERIVED PROTE

Q63259 Q62883 Q63795 Q64643 PTPases in neuronal tissues,

R394 F12e P Adenosine receptor A3

M94152 28647 Q63792 1.264 1.087 1.152 no

R338 F12f M64299 P25099 Adenosine A1 receptor 1.110 0.955 0.722 no

R406 F12g S47609 P30543 Adenosine A2a-receptor 1.000 1.213 1.116 no

R382 F12h M91466 P29276 Adenosine A2b receptor 1.000 1.023 1.181 no

R433 F12i 1.000 neonatal hyperparathyroidism)

U10354 P48442 Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe 1.000 1.501 no

RG112 F12j L26173 P25023 B2 bradykinin receptor (BK2 receptor; BDKRB2) 1.000 1.000 1.000 no

RG485 F12k 1.424 1.250 1.076 no

U10699 P47752 endothelial differentiation, sphingolipid G-protein-coupled receptor, 5

R497 F12l 1.156

U61373 Q63645 Proteinase-activated receptor-2, G protein-coupled receptor 11 1.000 1.604 no

RG008 F12m AJ002745 O35786 chemokine-like receptor 1 1.271 0.787 1.279 no

RG241 F12n S74702 P46090 G-protein copled receptor 1 1.360 0.768 0.993 no

RG263 F13a U12006 P51651 putative G protein-coupled receptor (CNL3) 1.000 1.000 1.500 no

RG264 F13b U12184 P30951 G-protein coupled receptor 12 1.165 0.661 0.946 no

RG307 F13c U65417 P70585 G protein-coupled receptor 19 1.510 0.929 1.022 no

RG477 F13d S77867 Q64121 G-protein coupled receptor 10 0.899 0.673 0.538 no

RG170 F13e M35297 P23749 probable G protein-coupled receptor RTA 0.714 0.604 0.621 no

RG118 F13f L27513 P55094 TR4 orphan receptor 0.864 0.713 0.733 no

R012 F13g AF003926 O09017 nuclear receptor subfamily 2, group F, member 6 1.087 0.702 0.871 no

R434 F13h Q62681 nuclear

U10995 Q62697 Q64114 receptor subfamily 2, group F, member 1 0.885 0.816 1.436 no

RG359 F13i X56917 P17105 inositol 1,4,5-triphosphate 3-kinase 1.186 0.937 1.003 no

R582 F13j X67788 P31977 villin 2 1.111 1.316 1.804 no

R570 F13k X59601 P30427 plectin 0.752 0.790 1.121 no

R451 F13l U19866 Q62743 activity regulated cytoskeletal-associated protein 1.151 0.532 1.095 no

RG254 F13m U06755 P37397 calponin 3, acidic 0.637 0.586 0.757 no

RG380 F13n X62908 P45592 cofilin 1, non-muscle 0.945 0.710 0.705 no

RG386 F14a X71071 Q08290 calponin 1 1.000 1.000 1.310 no

R494 F14b U58858 P70565 unction plakoglobin 3.087 1.097 2.836 no

R610 F14c Z46372 P41516 topoisomerase (DNA) II alpha 1.144 1.000 1.360 no

R532 F14d U89282 O08653 telomerase protein component 1 1.271 0.942 1.040 no

R105 F14e D44495 P43138 apurinic/apyrimidinic endonuclease 1 0.751 0.858 0.719 no

R527 F14f U80054 P97679 mismatch repair protein 1.067 1.000 1.354 no

R565 F14g X54862 P24528 O6-methylguanine-DNA methyltranferase 1.000 1.000 1.147 no

R599 F14h X98490 Q63528 p32-subunit of replication protein A 1.114 1.275 2.116 no

R198 F14i L08814 Q04931 Structure specific recognition protein 1 2.279 2.509 2.929 no

R692 Q neuronatin

F14j U08290 62649 Q62663 1.116 0.663 0.815 yes no

R591 F14k X91619 Q63540 Spinocerebellar ataxia type 1 1.000 1.065 1.713 no

R492 F14l U57715 P70561 FGF receptor activating protein 1 0.449 1.024 0.492 no

RG373 F14m X61381 P26376 interferon-inducible protein 16 0.499 0.836 0.805 no

R255 F14n M15527 P55248 Gonadotropin releasing hormone 0.726 0.903 0.628 no

R372 G11 D16554 Q63446 polyubiquitin

R029 G13 D00036 P04055 phospholipase A2, group IB, pancreas

R366 G15 M63983 P27605 hypoxanthine-guanine phosphoribosyltransferase (HPRT)

R367 P Glyceraldehyde-3-phosphate dehydrogenase

G27 M17701 04797 P09328

R373 P02551 alpha-tubulin

G29 V01227 P05212 P05210

R369 G31 J04791 Ornitine decarboxylase

P09057 Q63389

R370 V01217 actin, beta

G43 P02570 Q11211 P99021 Q64316

R368 G45 X68199 Q05096 myosin IB

R371 G47 X59051 P30054 Ribosomal protein S29

in situ hybridization

when and how P<

Hal 17/2h ↑, 17/24h ↓ 0.05

Clozapine 24h ↓ 0.001

Clozapine 17d 2h ↑ 0.05

Cloz 6h ↑, 17d 2h ↓ 0.05

Hal 17/2h ↑, 17/24h ↑ 0.05









Cloz 17/2h ↑, 17/6d ↓ 0.001

Haloperidol 17d 2h ↓ 0.05

Haloperidol 17d 2h ↓ 0.01

Clozapine 17d 6d ↓ 0.01

Cloz 6h ↑, 24h ↑ 0.05