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Scottish Medicines Consortium







SMC Evaluation Project



Laura McIver,

Dr Paul Catchpole,

On behalf of SMC Evaluation Management

Group



ABPI Conference, 17th November 2006

Scottish Medicines Consortium







Remit of Evaluation



• To assess the impact and effectiveness of SMC

Advice in NHS Scotland

• To inform Scottish practice around managed

introduction of new medicines

• To contribute to the wider understanding of

organisations that assess new technologies

Scottish Medicines Consortium



Project Team Links



SMC Management

group

SMC reference

group

Project team:

Bill Ramsay

NHS/Industry Marion Bennie

Groups/Networks Corri Black

Vicky Cairns

Sharon Hems

Samuel Oduro

Scottish Medicines Consortium





Industry and Organisations represented

on the Reference Group



• Martin Coombes, AstraZeneca

• Andrew McGuigan, Janssen-Cilag

• Jim Swift, Takeda

• Patient and Public Representative

• Bipolar Fellowship Scotland

• HIV Scotland

• NHS ADTCs / Chief Executive / Director of Finance

• University Academics

• Scottish Executive Health Department

Scottish Medicines Consortium







Programme Elements



SMC Evaluation Programme









Impact of SMC Evaluation of Evaluation of Supporting

decisions on SMC budget SMC’s linkage of

medicines forecasts with engagement clinical

utilisation resource with key information

across the usage within stakeholders and medicines

health care NHS Scotland utilisation data

system. over time

Scottish Medicines Consortium



Medicine Utilisation

Accepted Classification of Medicines Restricted

Unique Not Recommended Antimicrobials Cancer





Sample from

each group selected. Reviewed and verified by

clinical networks and Reference Group



Data Sources and Collection

Primary care Data (either per month or per quarter)

- Information Services Division

• volume/amount issued

Secondary Care

- Pharmacy Systems and Clinicians • total cost/expenditure for the medicine



Pharmaceutical Industry • no. of patients prescribed the medicine

Scottish Medicines Consortium





Medicine Utilisation

Data Sources and Collection





Analysis of data and draft report





Validation and Interpretation

via

Clinical Networks, ADTC Networks,

Reference Group and Industry





Issue report

Scottish Medicines Consortium



Classification of Data

Clinical Area Cancer Antimicrobials Unique / Other Total

Innovative



Recommendation type



Accepted 10 4 1 53 68



Accepted for 16 12 6 48 82

Restricted use



Not 10 5 1 41 57

recommended

Total 36 21 8 142 207

Scottish Medicines Consortium



Not Recommended Medicines

in Primary Care

£40,000







£35,000







£30,000

Restricted approval

Not Recommended by SMC

by NICE

Gross Ingredient Cost









£25,000







£20,000







£15,000







£10,000







£5,000







£0

2002/03 Q3





2002/03 Q4





2003/04 Q1





2003/04 Q2





2003/04 Q3





2003/04 Q4





2004/05 Q1





2004/05 Q2





2004/05 Q3





2004/05 Q4





2005/06 Q1





2005/06 Q2





2005/06 Q3





2005/06 Q4

Financial Year Quarter







Note: GIC obtained from Prescribing Information System for Scotland (PRISMS)

Scottish Medicines Consortium



Outputs



• Scottish patients access to individual

medicines reviewed by SMC

• Qualitative and quantitative data

• Generic key findings / learnings

• Recommendation next steps and actions

Scottish Medicines Consortium



SMC Evaluation Programme





Evaluation of

SMC’s engagement

with key

stakeholders.





Patient and Public Involvement Pharmaceutical NHS

Sub-Group (PAPIG) Industry





ADTC role and processes reviewed

Scottish Centre for Social

Key themes identified

Research

Opportunity exists to share experience

and identify examples of good practice

Scottish Medicines Consortium



Engagement with Industry



• Industry can provide the project with important

additional medicines uptake datasets:

• Secondary care

• Primary care

• To support both primary analysis (mainly

secondary care) and to cross validate and

supplement existing NHS datasets

• Evidence collection template (quantitative and

qualitative data) presently being finalised for issue

to companies

Scottish Medicines Consortium





Summary



• Work programme progressing well and to plan

• Challenges around data collection which can

partially be addressed by engagement of industry

• Validation and interpretation needs to be robust

• Contextual qualitative evidence also required to

support the quantitative information gathered

• ABPI and industry support crucial to the project



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