Subramaniam_abstract

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					NOVEL MOLECULAR AND CELLULAR IMAGING TOOLS AND
STRATEGIES
Vinod Subramaniam
MESA+ Institute for Nanotechnology & MIRA Institute for Biomedical Engineering
and Technical Medicine, University of Twente, PO Box 217, 7500AE Enschede, The
Netherlands
v.subramaniam@tnw.utwente.nl

Recent developments in new imaging modalities and novel fluorescent reagents, such
as semiconductor quantum dots, have revolutionized our ability to precisely localize
and visualize dynamic processes involving multiple molecular interactions in vitro
and in living cells at high spatial, temporal, and chemical resolution. I will focus on
multiparameter optical imaging strategies, combining intensity, spectral and lifetime
imaging, that enable the quantitative measurement and imaging of photophysical
events in nanoconfined structures and of molecular and cellular biophysical processes.
I will also touch upon our activities in optical super-resolution imaging, which
enables sub-diffraction limit visualization of biomolecules with unprecedented
resolution.

				
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posted:11/24/2011
language:English
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