Meet the Editorial Team
Professor Denys Wheatley is Co-Editor of Oncology News, and is Director of BioMedES.
Xeloda within 30 mins after a meal. Xeloda appears to down-regulate CYP He has strong research ties in Albany, Davis, Auckland, Valencia, Detroit, Budapest, St
2C9, no effect on 1A2 & 3A4. Side-effects: See SmPC for full list of adverse Petersburg, Heidelberg, Zürich and Hong Kong. He is eager to establish strong interaction with
reactions (ADRs). ADRs associated with Xeloda monotherapy in three major cancer and cell biology teams worldwide, and initiate programmes in the areas in which his
clinical trials in adjuvant treatment for colon cancer and for metastatic expertise lies. His work in cancer research, other scientific fields, with IFCB, and in publishing
colorectal cancer: Very common (> 1/10; all grades of severity): Anorexia, and scientific communication has led to his receiving awards in recent years.
diarrhoea, vomiting, nausea, stomatitis, abdominal pain, HFS, fatigue, asthenia.
Common (> 1/100 - Mr Patrick J Bradley is Co-Editor of Oncology News, and, a Head and Neck Oncologic
1/1000-< 1/100; grade 3/4 severity or medically relevant): Sepsis, urinary tract
infection, cellulitis, tonsillitis, pharyngitis, oral candidiasis, influenza, Surgeon at the University Hospital, Nottingham. He is a member of numerous journals’ UK
gastroenteritis, fungal infection, herpes infection, infection, tooth abscess, Editorial Boards; Journal of Laryngology and Otology, Oral Oncology, and International
lipoma, febrile neutropenia, pancytopenia, granulocytopenia, thrombocytopenia, Journals: Laryngoscope, Head and Neck, Acta Otolaryngologica Scandinavia, as well as
leucopenia, haemolytic anaemia, hypersensitivity, diabetes, hypokalaemia, Section Editor of Head and Neck Oncology, and Current Opinions ORL-HNS.
appetite disorder, malnutrition, hypertriglyceridemia, confusional state, panic
attack, depressed mood, libido decreased, aphasia, memory impairment, ataxia,
syncope, balance disorder, sensory disorder, neuropathy peripheral, visual
acuity reduced, diplopia, vertigo, ear pain, angina unstable, angina pectoris, Dr Tom Lynch is Assistant Editor – Imaging, and is a Radiologist and Lead Nuclear
myocardial ischaemia, atrial fibrillation, arrhythmia, tachycardia, sinus Medicine Physician in the Northern Ireland Cancer Centre based at the Belfast City Hospital.
tachycardia, palpitations, DVT, hypertension, petechiae, hypotension, hot flush,
peripheral coldness, pulmonary embolism, pneumothorax, haemoptysis, Tom specialises in PET/CT scanning and nuclear medicine with a special interest in paediatric
asthma, dyspnoea exertional, intestinal obstruction, ascites, enteritis, gastritis, nuclear medicine.
dysphagia, abdominal pain lower, oesophagitis, abdominal discomfort,
gastrooesophageal reflux disease, colitis, jaundice, skin ulcer, rash, urticaria,
photosensitivity reaction, palmar erythema, swelling face, purpura, joint
swelling, bone pain, facial pain, musculoskeletal stiffness, muscular weakness, Dr Heidi Sowter is Assistant Editor – Web Review, and is a Lecturer in Forensic Science
hydronephrosis, urinary incontinence, haematuria, nocturia, vaginal and Biology, at the Faculty of Education, Health and Science, University of Derby. Heidi
haemorrhage, oedema, chills, influenza like illness, rigors, blood in stool, INR
increased, blood creatinine increased, body temperature increased, blister, continues to pursue her research interests in gynaecological and breast cancer.
overdose. Laboratory abnormalities: Very common (all grades): Decreased:
Haemoglobin, neutrophils/granulocytes, platelets, lymphocytes, sodium,
potassium, calcium. Increased: Bilirubin, alkaline phosphatase, ALAT (SGPT),
ASAT (SGOT). Common (all grades): Increased calcium. Xeloda plus cisplatin:
ADRs seen in addition to or at higher frequency grouping than those for Ms Kathleen Mais is Assistant Editor – Nursing, and is a Nurse Clinician in Head & Neck
monotherapy: Very common (all grades): Neutropenia, leucopenia, anaemia.
Common (all grades): Herpes zoster infection, urinary tract infection, Oncology at Christie Hospital, Manchester. Kathleen qualified as a nurse in Newcastle-upon-
thrombocytopenia, bone marrow depression, hypokalaemia, hyponatremia, Tyne. Kathleen is a nurse-prescriber and runs a nurse-led chemotherapy clinic as well as
sleep disorder, neuropathy, peripheral sensory neuropathy, hypoaesthesia, continuing her work in clinical research.
tinnitus, hypoacusis, upper GI haemorrhage, mouth ulceration, gastritis, hepatic
function abnormal, hyperhidrosis, myalgia, mucosal inflammation, creatinine
renal clearance decreased. Uncommon (grade 3/4 or medically relevant):
Aleukaemic leukaemia, hyponatremia, dehydration, hyperglycaemia, decreased Marilena Loizidou is Assistant Editor – Colorectal, and is a Non-Clinical Senior Lecturer
appetite, dizziness, upper GI haemorrhage, constipation, mouth ulceration,
abdominal pain, renal failure, renal failure acute, fatigue, malaise. Xeloda plus in the Department of Surgery, UCL. Her research program focuses on aspects of colorectal
oxaliplatin: ADRs seen in addition to or at higher frequency grouping than cancer and liver metastases, from the basic underlying biology to new potential treatments.
those for monotherapy. Very common (all grades): Anaemia, leucopenia, The current focus of research is the contribution of the peptide endothelin-1 to tumour growth
neutropenia, thrombocytopenia, neuropathy. Common (all grades): Bleeding. and progression in the bowel. Additional research areas include breast and bladder cancer.
Xeloda plus docetaxel: ADRs seen in addition to or at higher frequency
grouping than those for monotherapy: Very common (all grades): Neutropenic
fever (grade 3-4), appetite decreased, taste disturbance, paresthesia, lacrimation
increased, lower limb oedema, sore throat, constipation, dyspepsia, alopecia, Alan Cooper is Assistant Editor – Urology, and is Lead Scientist with the urology research
nail disorder, myalgia, arthralgia, pyrexia, weakness. Common (all grades): Oral group in Southampton University Hospitals and senior lecturer (albeit with virtually no lecturing
candidiasis, peripheral neuropathy, rash erythematous, nail discolouration, burden) in the Department of Biomedical Sciences at Portsmouth University.
onycholysis, pain in limb, pain. Uncommon (grade 3/4 or medically relevant):
Headache, epistaxis, cough. Xeloda plus epirubicin & oxaliplatin: ADRs seen in
addition to or at higher frequency grouping than those for monotherapy: Very
common (grade 3/4): Leucopenia, neutropenia, lethargy. Common (grade 3/4):
Anaemia, thrombocytopenia, febrile neutropenia, peripheral neuropathy,
infection, fever, thromboembolism. Xeloda plus epirubicin & cisplatin: ADRs Michael Douek is Assistant Editor – Breast, and is a Senior Lecturer and Consultant Surgeon
seen in addition to or at higher frequency grouping than those for monotherapy: at University College London Hospitals focusing on breast cancer surgery with a particular interest
Very common (grade 3/4): Leucopenia, neutropenia, anaemia, lethargy, in pre-operative surgical planning using breast MRI. In 2003, he was awarded a prestigious
thromboembolism. Common (grade 3/4): Thrombocytopenia, febrile Health Foundation Clinician Scientist grant by the UK Academy of Medical Sciences, fully funding
neutropenia, peripheral neuropathy, infection, fever. Post-marketing experience his joint academic and clinical post in breast surgery.
(very rare serious ADRs): Lacrimal duct stenosis, hepatic failure & cholestatic
hepatitis. Legal Category: POM. Presentations & Basic NHS Costs:
Film-coated tablets containing 150mg capecitabine. Pack of 60 tablets: £44.47.
Film-coated tablets containing 500mg capecitabine. Pack of 120 tablets: Dr S Gokul is Assistant Editor - Journal Reviews, and is a Consultant Medical Oncologist
£295.06. Marketing Authorisation Numbers: EU/1/00/163/001 (150mg), at The James Cook University Hospital, Middlesbrough. His areas of interest are lung and
EU/1/00/163/002 (500mg). Marketing Authorisation Holder: Roche gynaecological cancers.
Registration Limited, 6 Falcon Way, Welwyn Garden City, Herts. AL7 1TW.
Registered in England No. 3028626. Further information is available on request.
XELODA® is a registered trade mark. Date of Preparation: May 2007.
Helen Evans is a Journal Reviewer for Oncology News. Helen recently worked as a Senior
Information about adverse event reporting can be found at
www.yellowcard.gov.uk. Adverse events should also Lecturer in Cancer Nursing at the Institute of Nursing and Midwifery, University of Brighton but
be reported to Roche Products Limited. following the birth of her son has returned to clinical practice as a Clinical Nurse Specialist at St.
Please contact UK Drug Safety Centre on: 01707 367554. Wilfrid's Hospice in Chichester.
Paul Carlin is a Journal Reviewer for Oncology News and is a registered Paediatric
and General Nurse. Paul is currently employed as a Clinical Trials Nurse at the Ulster Hospital,
Dundonald and is particularly interested in clinical trials work, quantitative research and HIV,
as well as oncology.
capecitabine
Dr Christopher W Perrett is Assistant Editor – Book Reviews, he is a Non-Clinical Senior
Lecturer in Obstetrics and Gynaecology at the Royal Free and University College Medical School,
London. His area of expertise is in the field of the molecular basis of gynaecological cancer.
J978738h Date of preparation June 2007
Volume 2 Issue 4 • December/January 2008 3