The Continuum of Stroke Care

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							The Continuum of Stroke Care




               Justin A. Sattin, M.D.
                Assistant Professor
          UW Department of Neurology
                 Medical Director
     UW Health Comprehensive Stroke Program
            The Chain of Survival



•   Healthful Choices    •   ICU Nursing Care
•   Public Recognition   •   General RN Care
•   EMS Access           •   More Radiology / Lab
•   ED Recognition       •   Inter-D Care
•   Radiology / Lab      •   Rehabilitation
•   Neurologist          •   Re-Integration
•   Pharmacy
Stroke Symptoms
                                 Cincinnati Prehospital Stroke Scale

                                              Facial Droop
                                              Instruction: Ask patient to smile
                                              o Normal:             Both sides of face move equally
                                              o Abnormal:           One side of face does not move as well



                                              Arm Drift
                                              Instruction:          Ask patient to close eyes and extend both arms straight
                                                                    out for 10 seconds
                                              o Normal:             Both arms move the same or not at all
                                              o Abnormal:           One arm does not move or drifts down


                                              Speech
                                              Instruction:          Ask patient to say “You can’t teach an old dog new tricks.”
                                              o Normal:             Patient says correct words without slurring
                                              o Abnormal:           Patient slurs words, says wrong words, or is unable to
                                                                    speak




Kothari RU, et al. Cincinnati Prehospital Stroke Scale: reproducibility and validity. Ann
Emerg Med. 1999;33:373-8.
Ischemic or Hemorrhagic?
Ischemic or Hemorrhagic?
                              NINDS tPA Trial
               35
               30

               25
               20                                                   Death
               15                                                   Hemorrhage

               10
                5
                0
                             t-PA                 Placebo



The National Institute of Neurological Disorders and Stroke rt-PA
Stroke Study Group. Tissue plasminogen activator for acute
ischemic stroke. N Eng J Med. 1995;333:1588–1593.
    39 – 26 = 13
39 – 26 = 13% absolute difference

10013
      = needed to treat
---------8= 50% relative benefit
 13 26
          Time is of the Essence




Hacke W, et al. Association of outcome with early stroke
treatment: pooled analysis of ATLANTIS, ECASS, and NINDS
rt-PA stroke trials. Lancet 2004;363:768-74.
Furlan A, Higashida R, Wechsler L, et al. Intra-arterial prourokinase for acute ischemic
stroke. The PROACT II Study: A randomized controlled trial. JAMA. 1999;282:2003-2011.
Mechanical Embolectomy




                         Leary MC, et al.
                         Beyond tissue
                         plasminogen
                         activator:
                         mechanical
                         intervention in
                         acute stroke.
                         Ann Emerg
                         Med.
                         2003;41:838-
                         46.
Courtesy of Concentric Medical, Inc.
Mechanical Embolectomy
 Annual Stroke Mortality
      2001-2004




 Avg# of deaths per county per year
 (total for all counties in group)

        <10 (64)                     50-100 (1,067)

        10-50 (1,033)                >100 (1,186)



Yuan, H. and Brue, C. Wisconsin Heart Disease and
Stroke Surveillance Summary Update – 2007 – PPH
43040 (01/07). Wisconsin Department of Health and
Family Services, Division of Public Health.

The Joint Commission. Available at:
http://www.jointcommission.org/CertificationPrograms/Disease-
SpecificCare/DSCOrgs/ Accessed 10/14/07
  General Management Principles
• Hypoxic pts. should receive O2
  – SpO2 > 92%


• Cardiac monitoring for at least 24 hrs.

• Treat HTN conservatively for 24 hrs.
  – Ischemic:          SBP < 220 mmHg
  – Hemorrhagic: SBP < 160 mmHg
  General Management Principles
• Minimize urinary catheterization

• Fevers should be evaluated and treated

• Hyperglycemia should be treated
  – Optimal threshold is not established
  – < 140 mg/dL? < 185 mg/dL?
  General Management Principles
• Dysphagia screening

• Early mobilization

• DVT prophylaxis
  – LMWH
                      Stroke

Hemorrhagic                                        Ischemic
                                                          Cardioembolic
                                                          Large artery athero.
ICH         SAH
                                                          Small vessel dz.
                                                          Other
                                                          Unknown

       Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE 3rd.
       Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical
       trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35-41.
                                          Stroke

                                                   Ischemic
                                                    Cardioembolic
                                                    Large artery athero.
                                                    Small vessel dz.
                                                    Other
                                                    Unknown

http://www.florida-oxygen.com/treatment.htm
                                             Stroke

                                                             Ischemic
                                                              Cardioembolic
                                                              Large artery athero.
                                                              Small vessel dz.
                                                              Other
                                                              Unknown

http://www.cardioliving.com/consumer/Stroke/AF_Causes.shtm
Cardioembolic Stroke
            Stroke

                                      Ischemic
                                             Cardioembolic
                                             Large artery athero.
                                             Small vessel dz.
                                             Other
                                             Unknown


http://biocomp.stanford.edu/3dreconstruction/movies/haveri/stenosis_ica_angio%26ssd.jpg
Stroke

         Ischemic
          Cardioembolic
          Large artery athero.
          Small vessel dz.
          Other
          Unknown
                                               Stroke

                                                          Ischemic
                                                           Cardioembolic
                                                           Large artery athero.
                                                           Small vessel dz.
                                                           Other
                                                           Unknown
http://bbh.hhdev.psu.edu/courses/368/slide.21.(164).htm
Stroke

         Ischemic
          Cardioembolic
          Large artery athero.
          Small vessel dz.
          Other
          Unknown
        Risk Factor Modification
•   Hypertension
•   Diabetes
•   Dyslipidemia
•   Metabolic Syndrome
•   Tobacco Dependence
        Antithrombotic Therapies
•   Aspirin
•   Aspirin/Dipyridamole (Aggrenox)
•   Clopidogrel (Plavix)
•   Warfarin (Coumadin)
     Important Collaborators

•   PT        •   Health Ψ
•   OT        •   Case Managers!
•   Speech    •   Social Work
•   Swallow   •   Pastoral Care
•   Rehab     •   Palliative Care
•   Neuro Ψ   •   ACE Team
           Discharge Dispositions
• Home
    – often with outpt. or home health therapies)
•   Acute Rehab
•   Subacute Rehab
•   Skilled Nursing Facility
•   Hospice
•   (Celestial Discharge)
  Vascular
 Cognitive
Impairment
          How to Reach Us
Emergent Referrals    Office Referrals
UW Access Center      UW Stroke Clinic

Phone: 800-472-0111   Phone: 608-265-8899
                       Fax: 608-265-1753

						
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