CALIFORNIA
TUMOR TISSUE REGISTRY
"LUNG AND MEDIASTINAL PATHOLOGY"
Study Cases, Subscription A
October 2000
California Tumor Tissue Registry
do: Department of l'atbology and Human Anatomy
!Alma Linda Universily School of Medicine
11021 Campus Avenue, AH 335
Lorna Linda. California 92350
' (909) 558-4 788
FAX: (909) 558-0188
E-mail: £!!!@linklinc.cont
Target audience:
Practicing pathologists and pathology resideniS.
Goal:
To acquaint the participant with the nisrologic f""tures of a variety of benign and
malignant neoplasms and rumor-like conditions.
Ob!eetlves:
The participant will be able to recognize morphologic features of a variety of benign
and malignant neoplasms and tumor-like conditions and relate those processes to
pertinent references in the medical literature.
Educational methods a nd media:
Review of representative glass slides 'vith associated biSiories.
Feedback on consensus diagnoses from participating pathologiSIS.
l.isting of selected references from dJeJDedicalliterature.
Principal faculty:
Weldon K. Bullock, MD
Donald R. Olase, MD
CME Credit:
Lorna Linda University School of Medicine designates this continuing medical
education activity for up to 2 hours of Category r of the Physician's Recognition
Award of the American Medical Association.
CME credit is o.frered for lhe subscription year only.
Accreditation:
Loma Linda University School of Medicine is accredited by the Accreditation
Council for Continuing Medical Education (ACCME) to sponsor continuing
medical education for physicians.
Contributor: Charles I. Goldsmith, M.D. Case No. 1 - October 2000
Santa Monica, CA
Tissue from: Left pleura Accession #28892
Clinical Abstract:
While being evaluated for pneumonia, this 56-year-old man was noted to have a pleural-based
mass on the left side. One year earlier a chest x-ray had been normal. A 6.5 em mass was resected
along with attached parietal pleura. During routine follow-up eight years later, a CT scan revealed a
Tecurrent disease in the form of multiple pleural nodules. These were resected.
Gross Pathology:
An en bloc resection of ribs and soft tissue included three tumor nodules up to 2.5 em in
greatest diameter.
SPECIAL STUDIES:
CD34 moderate to strongly positive
Vimentin strongly positive
CD31 weakly positive
Keratin negative
SIOO negative
Actin negative
Contributor: Paul Meyer, M.D. Case No. 2 - October 2000
Los Angeles, CA
Tissue from: Pleura Accession #26863
C linical Abstract:
After working for 40 years as a Longshoreman, with numerous exposures to asbestos, this 68-
year-old man presented with a two week history of difficulty breathing. Following biopsy, be was sent
home with oxygen. After a second attack of shortness of breath, he was re-admitted and expired one
week later. An autopsy was performed.
Gross Pathology:
Autopsy findings included a tumor involving mediastinum, pericardium and left pleura along
with multiple pleural plaques on the left side.
Contributor: K. Greg Peterson, M.D. Case No. 3 - October 2000
Sioux Falls, SD
Tissue from : Medias ti.n um Accession #28905
Clinical Abstract:
Following a one-year history of left shoulder pain, this 11-year-old girl was found to have no
breath sounds on her left side. ACT sean showed a left sided mass with calcifications. At surgery, a
left sided mediastinal mass was found compressing the left lung. The tumor had ruptured and caused a
local reaction making the resection difficult due to adhesions.
Gross Pathology:
A 730 gram shaggy but encapsulated~ was 14.5 x I 0 x 9.5 em. The cut surface showed
variegated, multicystic fibroadipose tissue with focal calcification and larger cysts containing grumous
yellow-tan material.
Contributor: Pamela Boswell, M.D. Case No. 4 - October 2000
Sa.n Diego, CA
Tissue from : Mediastinum Accession #28751
Clinical Abstract:
This 33-year-old female was found to have a large anterior mediastinal mass.
Gross Pathology:
The I0.0 x 2.0 x 1.0 em fatty specimen included a 5.0 x 5.0 x 5.0 em mass.
Contributor: LLUMC Pathology Group (np) Case No. 5 - October 2000
Loma Linda, CA
Tissue from: Right lung Accession #28725
Clinical Abstract:
A lobectomy was performed on this 70-year-old male with a right upper lobe mass.
Gross Pathology:
The 224 gram lobe contained a 5.1 x 4.1 x 4.0 em firm, yellow mass within the largest
bronchus. The mass extended peripherally to the pleura.
SPECIAL STUDIES:
Chromogranin 1-2+
NSE 4+
CAM5.2 4+
Contributor: LLUMC Pathology Group (rc) Case No. 6 - October 2000
Loma Linda, CA
Tissue from: Right lung Accession #28874
Clinical Abstract:
After a reported 10 pound weight loss, this 75-year-old Caucasian male was found to have a ~.5
em cavitary lesion in his right middle lobe. He had a long history of chronic obstructive pulmonary
disease associated with a 60 pack-year smoking history.
Gross Pathology:
The I I0 gram right upper lobe contained a 5.0 x 5.0 x 3.4 em white-tan nodule which was
located 5 em from the bronchial margin and extended to the superior and inferior pleural surface.
Contributor: Philip Robinson, M.D. Case No. 7 - October 2000
Boynton Beach, FL
Tissue from: Right lung Accession #28701
Clinical Abstract:
An 80-year-old male presented with a nodule in the middle lobe of his right lung.
Gross Pathology:
The II 0 gram lobe oflung was 12.2 x 9.2 x 2.6 em and had a 2.0 x 1.8 x 2.6 em gray nodule
which infiltrated through the visceral pleura.
Contributor: Joseph Carberry, M.D. Case No. 8 - October 2000
Los Angeles, CA
Tissue from: Right lung Accession #26198
Clinical Abstract:
During workup for dyspnea, this 59-year-old male was found to have a pleural effusion on the
right with an underlying tumor mass on the diaphragm.
Gross Pathology:
The resected right lobe oflung with attached portion of diaphragm was 2200 grams and 20.0 x
16.0 x 12.0 em. Tt contained a 15 x 12 x 12 em gritty white tumor with areas of hemorrhage and
softening.
SPECiAL STUDIES (outside facility):
Keratin negative
SlOO negative
CEA negative
EMA negative
NSE negative
Desmin negative
Virnentin strongly positive
Actin focally positive
Contributor: Octavio.Armas, M.D. Case No. 9 - October 2000
LaMesa,CA
Tissue from: Left lung Accession #28921
Clinical Abstract:
For two to three weeks this 72-year-old Caucasian female experienced cough and chest pain. A
chest x-ray revealed a large left lung mass.
Gross Pathology:
Within the parenchyma of the 20 x 18 x 12 em left lower lobe was a 12.0 x 11.0 em globoid,
necrotic tumor mass. ·
SPECIAL STUDIES:
Cytokeratin cocktail positive
Vimentin positive
Chromograoin negative
Desmin negative
Contributor. Pamela Boswell, M.D. Case No. 10 - October 2000
San Diego, CA
Tissue from: Left lung Accession #28877
Clinical Abstract:
After experiencing fatigue for six months, this 64-year-old female was found to have a left
lower lobe mass.
Gross Pathology:
The 17.0 x 13.0 x 3.5 em lobe oflung contained a 3.4 x. 2.5 x 1.8 em spongy, hemorrhagic,
mottled gray-tan tumor.
CALIFORNIA
TUMOR TISSUE REGISTRY
LUNG AND MEDIASTINAL PATHOLOGY
Minutes- Subscription A
October 2000
SUGGESTED READING (General Topics from Recent Lllnaturr):
Association Between Medications TI1at Relax the Lower Esophagral Sphincter and Risk for Esophageal
Adenocarcinoma. Lagergren J, Bergstrom R. Hans-Oiov A, and Nyren 0. Annals of /merna/ Medicine 2000;
133(3): 165- 175.
Mandatory Second Opinion Surgical Pathology at a Large Referral Hospital. Kranz JD. Westrn WH. and Epstein Jl.
Cancer 1 999~ 86(11):2198-2220.
Embryonal ~Botryoid" Rhadomyosarcoma of the Lruynx. A Clinicopathologic and lmmWlohistocbemical S!Udy of
Two Cases. L.ibera DO, Falconicri G and Zanella M. Annals of Diagnostic Pathology 1999; 3(6):341-349.
"Vinual Microscopy" and the lnlcntet as Telepathology Consultation Tools. Diagnostic Accumcy in Evaluating
Melanocytic Skin Lesions. The Am J ofDermatopathol 1999; 21(6):525-531.
California Tumor Tissue Registry
c/o: Department of Pathology and Human Anatomy
Lorna Linda University School of Medicine
11021 Campus Avenue, AH 335
Lorna Linda, California 92350
(909) 558-4788
FAX: (909) 558-0188
E-mail: cnr't1 hnklinc com
Case o f' the M - HemangiopcriC)1oma
Illinois wns fPerkshjn: Medicol Center> · Solitary fibrous tumor
Massachusetts CNew J.ogtund Medical Center) - Solitary JibtO\ISturnor of p letlr'd
Canad;l Cfoolhil!s I lpspjlol, Call!l!O'l • Solitaty fibrous tumor
Jopan turcs ofSolitllt) FibrotLS Tumor of the Pleuru. A Swdy of5 Cuscs.
Diagn Cyropatho/1998: 18(2):1 18·124.
1\pple SK. Nleb.:111 RK and Hirschowit7 SL. Fine Needle Aspirutioo Biopsy of Solitary Fibrous Tumor of the Pleura. A Repo11 or
Two Cases with" Discussion ufDingnostic Pitfalls. Acta (vto/ 1997; 41(5): 1528- 1533.
2 ClTR, Octobc.. (S.borna (7)
Sanm tl!l!a !!.oma Priellll • Mali(!l1ant mcsotbclioma (6)
Vemym - Mesolhelioma. biphosic
Wjscnns!n{Mclj!$rl - f)itfuse maligntU1l ltlCSOihclioma, biphallio type invoh•ing rw ietal and visceral pleura with inva'1iOil of the
lung
Louj:tkt!)Q. - DiflUse mnligo..'lnl mesothelioma epithelial type
!'!prj@ . Mesothelioma
Canac!a (Foothills I-lospjtal Calsarvl • Mesothelioma
JnpM !Kvotol - Mali(!l1ant mcs01hclioma (J)
JllO!VIo Kl!!llshiki 5pitali · Mali(!l1antmewt.hcliomo (~)
Sjnya('!('!r( • Mesothelioma
Snuslj Ambia -ation ofp53 Gene Product in Bc-nlgn Mesothelial and Adenocarcinoma Cells. Mcd Pmlto/ 1994: 7(~):462-46&.
An3Dd /1. PrognOStic Faetors of Malignant MCSO!hclioma of the Pleura. Cancer 1994: 73(3):755.
Cristlludo A. Vi>-aldi /\. Sc:nsalc:s G. •1 al. Molecular Biology Studies on Mesothelioma Tumor Samples. Preliminary lJata on H·ros.
p2 I and SV40. J £11Viron Pnrhol TmiCtJI Onco/1995: 14( 1):29-34.
ober
CTTR. Ck1 2000 -Min1.1te;;.. (Subli - Muturc ~ ri c teratoma
Ri\eajdc - Teratoma. maaun:
Onklood CKaiwrl - Marurc lctllloma (•I)
Sehwuoool I - Mature tcr111oma
Wisconsin fMcrjtsr) - Mature teratomn
lp uisjrma 0-.00j~jMn State University Medical Center> - MatlU'C tcnl.lOnll\
!lljnojs :tralobular pulmonary sequestration. (I..) thor!IX - media>1ionl r..onc
Kentucky CUnhmitvofLoyjsyille Rqjd;:ntsl • Bronchogenic c~'St
EJorjd.' 1Monroe Rc•ionnl Modjca! Ccntql - Benign teratoma
Florida {Wimer Haven! - Benign (mmure) teraromn (3)
Florida !Tallaha•=J - Teratoma (4)
Nooh Cwvljnn !WNC Patbg!ogy Group\ - Mature tctaiomo (3)
MnrvJj\Jid IWoodbjncl - Moturc teratoma ( 1}: Hamrmoma ( I)
MfiO'lnnd CUnjvcrsityofMorylandl - MallJre teratoma
New J - Hamartoma
New York CNcw J Iyde Park) • Mature teratoma
Mr"mtrfn.ascn., {)krkshin: Medical Cemer) - Congenital cystic acknomatoid malform(lllon vs. mature cystic tcrotoma
Massachusett'i · Mature cystic teratoma
OIACNOSIS:
Mature cystic teratoma. mediastinum
T-Y2300. M-90800
RT;EERENCES;
'l
Robinson LA, Rik.kcrs I. E Wd Dobson JR. Denign Moc Surg I 994: 58(2);545-548.
Dehnymoma
QdklandfKajserl • Th)moma.l)mphoc)te prcdooiinant (4)
SgbqsJO!Xll (f>mho!ogy Services! • Favor lh)moma. !)mplioe)te ricb · (need immunostains)
Mcmterey(Commuuity Hospital ofMnmcrcy Peninsula) .. Thymoma, l }mphoc)1~: predominant
Bllkendield · Lymphoc)1e predominllnt thymoma
Long Bench • Thymoma (7)
Santa Oarn C!.pma Prieta\ • Hodgkin'$ disease (6)
\fmoma
l ln>ward!FremoJl! • Lymphnc}te predominant tbymomu (3); M .ulignantlymphoma, small l>mphoc)tic, type (2)
Nevada I Reno\ • Thymoma. l)mphoc.)1c predominant
\Vjsoon.·oluted th)mus Jl)and
l.ooisiana floujsiaoa S!a!e Universitv Mc!lical Ce!l!er\ • Th)moma. mixed l)mphoepithelial
Illinois !Duoogc Pathology Associates\ • Likdy molisnantl)mphoma. rult out low·grnde MALT-assoc:iated type (th>mus)
Michigan IOJkwood HosojJall • Th)mOmie Hodgkin's (so-mphocytic ?) (I OJ
Nc"' Ywk CBeth l::racl Medical Ccmer Jlgsidcntsl .. 1l1ymoma
New York (New llvdc Park\ · Th)momo. cortical typo
M3SSl'.chUS£t)slllq!;shirc Medical Center) • Th)"ltloma vs. ll-«11 th)mic lymphoma
Massachusctt. &min Diogn Pat/1011990: 7(4):250.265.
Koga K, Matsuno Y. llil!l•chi M, et al. A Review 1'79 Th)mmnas. Modificotion ol'Smging $)11em and Reappraisal of
Conventional Division into lnvnsivo Olld Non-Invasive Til)'llloma. Pnthollw 1995; 45(1):87·89.
Cooper JD. CU11'Cn1 Therapy for Thymoma. Chest 1993; 103(4 Suppi):334S-336~.
Sustcr Sand Rosui J. Cystic Thymomas. A Clinioopnthologic Study ofTen Cases. Cancer 1992: Ci9(1):92·97.
CTTR. October 2000 ..M 1
nu1es"' (SubscrtpttOn A)
Cau No. S, Aeeession No. 28725 Odober 2000
LLL J MC J •uthology R esidents - L..nr,'\: cell n..:uroendt)Crine carcinoma
Mauntain Vjcw IE! Camjno Patbolocy Group) - Atypical careinoid
Rjyccsidc - Carcinoid
Oakland (Kaiser) - Wcl!-d!H'cremiwcd neuroendocrine carcinoma (4)
S.:bi!stQQOI C!'a!bologv Services) - At)'Pica! c:arcinold tumor
Monterey (Community Ho.•mjtal of Monterey Peninsula) • NeumendO·ealty of Morv!nndl • Neuroendocrine carcinoma, grudc lll
New Jersey {Ovqlook HospjtaD - L.argc cell neuroendocrine carcinoma (4)
f,cnnsylvuniu 11 -&hjnb ynllev J lo~m jtuU · Atypical carcinoid
Ps:nrmivania - Squamous cell carcinoma
Bakersfield - Squamous cell carcinoma
Long Bcacb - Squamous cell carcinoma (7)
Santa Clara (Lorna Prieta> - Squamous carcinoma (6)
Ventura (Unilabl - Well- · Adcnosquamous carcinoma (3)
Florida CT!lJiahasscel - Squamous cell carcinoma with basaloid featUre) - Squamous cell carcinoma (2)
Japan Kurushiki (Ka wosaki Medical School Hospital) - Squamous cell carcinoma(4)
S
Sintm:pore - SquammJ ce.JI carcinoma with ucanthol}1ic and ctenr cell fearures
Saudi Arabia (King Khalid University Hospital> • Basosquamous carcinoma
DIAGNOSIS:
Sq uamous cell carcinoma, lung
T-28000, M-80703
REFERENCES:
$
l)ejui·Thivolct F, Liagrc N. Chignol MC. el al. Deletion of Human Papi11om a Virus DNA in SquamOU Bronchial Metaphll.sin and
Squamous Cell CarcinomitS of tho Lung by In-Situ ~lybridigz.atiori Using Biotinylaled Probes in .Paraffin-Embedded Sp · Muoocpidcnuoid carcinoma
Bakersfield . Poor!) diffi!tmiated adenocamnoma
I.,Qng Beacb • Mucoepidermoid carcinoma (high grade) (7)
Santa CIO!ll! Lorna 1dc't1l) · Mucoepidermoid CArcinoma (6)
1
Vcn!!p !lJnjlabl • Squamous carcinoma wilh mucin production (2)
Sqrua Roou • Bronchogenic "S. ~
l,ouisiana UA>uisiqno S1ate lJniycrsitv Medical Center) - Squamous a:Jl avcinoma
lllioojs fDuouoe Pathology A • Adcnocan:inoma
filorida - Mucoepidermoid curcinoma (I); i\dcnosquamous carcinomo (1)
Moryland Cllni>-ersitvo(Man1andl · Non-small ocll carcinoma wi~l giant cells
New Jersey !Oyerlools Hospilllll · Adcnosquamous carcinoma (2); Mucocpicknnoid can:inoma (2)
l'ennsylvaoju CLehjoh Valley liospitnll • Non small cell carciooma ( I); Adenosquamous carcinoma (1)
Pcnns,1wnja !Coosmaug!J Mcdjcal Csn!er Residents) · Acinar (tubular) adenocarcinoma ofbronchial glund
New York CSVNY Swnv B!!Jlor JR. Sl:oscy C. t1 ol. Adenosquamous Lung Carcioomll. Clini · OstCOSW"CCilUt
Ri,·ersjde • Sarcoma. high grade
9alllarnl IKaixrJ - Pleomorphic lciomyosan::oma (4)
Sebastopol • Sarcoma (favor rhalxJomyQ$01CQma)
Monterey C CnmmunHy Hospilft] of Monterey Peninsylal · Surroma. rhabdomyosarcoma
Bakersfield - lligh grade sarcomu, rulu out muscle origin
Long Beach • l ligh grade sarcomo (myogenic} (7}
Santa Qj!!j!{!,gma PrietaI • Saroomo, NOS (6)
Ventura lllnil3bl • Pleomorphic rholxlomyosarcoma (2)
Santa Rosa • Ma!ignantmescnch)mal neoplasm, possibly myosarcoma (I); SarcorniL possibly rllabdorn)'OSlll'COOln (I)
Sacramento tUC payis Health S"'tcm3l - Poorly diftC rcntiatcd sarcoma favor leiomyosarcoma
1-!avward/Frcmom - Desmoplastic myosarcoma (2); l'Irnorphic librosarcorno ( I); Pleomorphic mo!ignam fibrous histiocytoma ( l)
Ncyada • tciomyosarooma vs. high grade s:~toomo
Wi§C!QQ,tioc)1oma vs. malignanl meseoch)malrumor
Illinois hic sarcoma
Florida IMoome Rc•ional Mes!iCAI Ccrncrl • Leiomyosarcoma
Florida IWinrer I Lwcnl - Sarooma (MFH) (2); Malignant fibroos mcsothclioma (I)
!'lorida ITal!ahamel • M)'Osarcomo. rhabdomyosaroorna
Nonh Carolina I WNC Patholoov Grouol • Sarcoma ? MFI I? Osteo (2); Sarooma. high grade ( ll
Maryland IIVtCOmo (2): Angiosnrcomo (3)
Canada lft)(lthillrous histiocytoma ( I)
Singaoorc • l lif!)l grade malignant tumor suggesti\'e of malignant fibrous histiOC)toma
fu!udi Ambia I!Gp• .Khalid Uni.-crsil> llosoita!l • Pleomorphic lciom)osatcorna
DIAGNOSIS:
Pleomorphic high grade sarcoma (M FI-1 pb•noty!l") with focal osseo us difTcrcntintion, lung
T-28000. M-88023
REFERENCES;
McOonndl T. K)Tinkos M, Roper C and Ma.roujian 0. Malignant Rbrous !listioc)toma ofthe lung. Ca11cer 1988: 61( 1):137-145.
Yousem SA ond Hochholzer L Malignant Fibrous HistiOCytoma t)f the Lung. Cancer 1987: 60:2532-254 1.
Vigucra Jl.. Pujol JL Rcboiros Sl>. et ol. Fibrous l listiocytoma orthe Lun~;. 71wrat 1976; 31(4):475-179.
aijad SM, !lcgjn i.R, Dail DH and Lukeman JM. Pihrn"' l listioc)1oma or Lung. A Clinicopathologic Study of rwo Cases.
Hisriopatholog,v 1981: 5(3):325-334.
CTTR. ~Iober 2000 ..Mmutcs.. (SubscnpctOn t\) 9
Case No. 9, Accession No. 28921 October 2000
I,!.UMC Patholoov Residents • Malignant spindle eelltumor (lllOilOpbasic $)'110viol sarcoma vs. rare CK+ MPNST. (!(
leiomyosarcoma)
Mountain Vi"'' lEI Camino !'l!Jbo!ogy Gn>uol • Sarooma!oid carcinoma
Rlyer - Saroomu
Bnkeo;field • San:omatoid carcinoma
!..ong [leach - 1'1scudosru·c(lllliltous corcioomll (7)
Soma Qftr!l 0.90Ju Priaal · Carcinoma with spindle and giant teinoma (saroomatoid c:arcinomn)
liayward!l'remoOJ • Dediffcrentimcd (metaplastic) lnrge cell carcinoma (3): Pleomorphic carcinoma (2)
Nevada !Reno) • Sarcomatoid can:incma
Wjsoonsjn !Mcrjterl • l'leomorphic malignnnl spindle und giunt eel! tumor involving luns. consistent with spindle ocll (sarcomatoid)
carcinoma. rule: out mas from ss
L&yjsiana (L oujsiooa S~;~te tJnjvcrsity Medicpl Center) - Carcinoma with sarromatoid rcatures
Illinois athoJt)gy Associate~) • High grade saroo1 natoid carcinoma. Jung
Michigan ( Oakwood tlospilAll - Carcinoma. sarcomasoid/spindle cell '-arinm
Indiana lfon Wamel - Sarcomatoid carcinoma. le n !ower lobe lung
Kcntuckv roomatoid curcinoma (2); Carcinosaroomu (!)
Mao·land CWonslbioel • Synovial saroomn (2)
Mwyland CUni\·crsjtvofMarv1 flQdl - Sarcomatoid carcinomu
New Jcr;jcy COycrlook llosoimll • Sarcoma/? Pscudosaroommous auciOC!rcoma favor leiomyosarcoma, would ~rform SMA and ca!desmin scains to oonfirm ohintic
o
Mountain View CEI Comjr Pqthology Group) ~ Oronchioalvoolar carcinr
XJ nu
Rjycrsidc - Oronchoalvcolnr carcinoma
Ooklwtd (Kaiser) • llrunchioloolveolar carcinomo ( 4)
Sebastonol rpathology Scrvjcesl ~ Bronchioal,·eolar l)'pc adenocarcinoma
Mootaey fCommunirv l lo;sPitaJ ofMomen...;y Penjnsulgl llronchoah·oolar cell carcinoma 4
llakcr:sfidd Bronchiolooh'COiut catcinoma
0
l.onu Beach Aden~inoma (bronchoalveolar t}'pc) (7)
0
Santa Clara (LQma Prjctul Adenocarcinoma with bronchioah' .. Broncho-alvcolar c.:arcinorna
llljnois C0UP..1£e Pathology A:;socjmc:s> - Mucinous bronchioloat,·eolat carcinoma
Mk hjgan (Oakwood 1-!osnjta!l - Adeoocarcinomu. papillary type
Indiana MuciOOU$ bronch-nlveolar cru-cinoma
0
Nnnh Carolina CWNC Pathology Group) - Oron - Bronchioalveolar CI:V'cinoma. memstatic carcinoma to lx excluded
Mas.suchuselt~ fBcrkshjr" Mcdjcnl Center> · Bronchioloul\·eolar carcinoma. non-mucinous c ype
MiL.$Sachusetts l'New Englund Medical Center) .. Uronchioah•eolar carcinoma ( I); Metas[atic adenocarcinoma (2)
Cunusb !Fooahillslio. ofllronchoolvoolar Can. oomu
;
and Conventionall'lolmmmry Adenocarcinoma. An lnununohistochcmi!:lll Stud). AmJ Surg Pathol 1992: 16(7):675-686.
Tuo LC. Weisbrod GL. I'"'"""" FG, ea al. Cytologic Diagnosis of'Bronchoalveolar Curci noma hy Fine Nc"Cdle Aspiralion Diops~.
Cancer 1986; 57(8): 1565°1570.
A"'\iotcs C:'\ and Jc:nnings 'l'A. Observations on Uroncho--AI ''ooJ Cnrcinomns with Special Emphash on l"'lcalized L~s ion. A
ar
Clinioopathologicol. Ultra.. (SubscriptiOn A) II