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PRESS RELEASE

Some clarifications concerning inaccurate news spread by the media,

with special reference to Dr Zivadinov’s study published in the April

issue of Neurology.





CCSVI is by full right to be included among the causative factors

of MS since it was found in 60% of the pediatric forms of MS.





The published data - disclosed in 2010 – were already then regarded

as confirming data.





The study - conducted by the researchers at the University at Buffalo on

the relationship between CCSVI and MS and published in Neurology (journal

of the American Academy of Neurology) on April 13, 2011

(www.neurology.org) - is causing quite a stir, but this piece of news requires

some clarifications.

As a matter of fact, these studies are said to disprove the theory according to

which there is a relationship between CCSVI and MS, highlighting the fact

that CCSVI is not a cause but rather a consequence of MS.



Indeed, the study published in Neurology further confirms the findings

of last Spring; in fact, both the study and the data it contains are the same

as those disclosed in a press release in Spring 2010 and described as

confirming data.



These findings are in line with those presented at the Live Web Forum

organized by the National MS Society in Toronto on April 14, 2010, also

attended by Prof Paolo Zamboni, Director of the Center for Vascular

Diseases of the Ferrara University and discoverer of CSSVI, Dr Robert

Zivadinov from the University at Buffalo, Dr Andrew Common, radiologist at

St. Michael’s Hospital, University of Toronto, and Dr Aaron Miller, Professor

of Neurology and Director of the MS Center at Mount Sinai, New York. During

the Live Web Forum – followed live by physicians and patients from 5

continents - both these 4 experts and the attending scientists regarded the

Buffalo study as a confirmation study. Indeed, the analysis of the data led to

the conclusion that CCSVI was also a negative prognostic factor for the

course of MS.



For this reason the data need to be interpreted in a different way.

Prof Zivadinov‘s findings do not prove Prof Zamboni‘s work wrong, contrary to

what other sources have incorrectly reported to the media. Instead, his data

strongly support the fact that – in a multifactorial perspective largely

accepted by all scientists - CCSVI is by full right to be included among

the causative factors of MS, since it was found in almost 60% of the

pediatric forms of MS and in almost 40% of the subjects with Clinically

Isolated Syndrome (Cis). Clearly, being present in most pediatric forms, it is

difficult to consider CCSVI as a consequence of MS.





Press Office: Francesca Rossini Manfredini - Laboratorio delle Parole

Tel. +39-051-0950120 – Mobile +39-335-5411331 or +39-331-6752354 –

francesca.rossini@laboratoriodelleparole.it



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