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University of North Carolina at Asheville

INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE

ASSURANCE OF ANIMAL CARE FORM



The UNCA Institutional Animal Care and Use Committee must approve all research, teaching and

diagnostic projects using live vertebrates prior to commencement of activities or acquisition of animals.

Submit the completed Assurance of Animal Care form to the Chair of the IACUC Committee



Note: When completing this form do not "refer to" your proposal, lab manual, project reports, previous

publications, etc. These documents rarely have the necessary information to evaluate your animal use

protocol(s). If appropriate you may attach supporting information.



We only accept electronic submissions (supporting information may be submitted separately if not in

electronic format). Send e-mail submissions to the IACUC committee chair. Please put “IACUC

Animal Care Form” on the subject line of your e-mail and indicate in the text of your e-mail that

you are submitting an Animal Care Form as an attached document. Always check to be sure that

we received the document and remember: you must still sign the declaration page. This may be

done in person or you may print off the declaration page, sign it and send it to us by campus or regular

mail. Your protocol will not be approved until complete.



If you are unclear as to what is required to complete this form please contact the IACUC for instruction.



This protocol will be valid for 12 months after approval and must be kept current, especially with

respect to new methods or techniques as they evolve (see Appendix listing significant changes to animal

use protocols). Please obtain the required forms for submitting a modification. As stipulated in the

Animal Welfare Act and Public Health Service Policy, this protocol may be renewed annually by the PI

for a maximum of 2 renewals. You will receive an annual review form from the IACUC for 2 years and

on the third anniversary of this Assurance you will be notified of its termination. At this time you will

need to submit a new protocol for review. Following approval, an IACUC number will be assigned to

this protocol. All lab animals and captive wildlife used under this Assurance of Animal Care Form must

be identified with the assigned IACUC number by using cage cards, door cards, or some ready method

of identifying pens or paddocks with this Assurance.



Only UNCA Faculty can be directly responsible for projects involving vertebrates. Students and staff

may fill out this form but their immediate supervisor is responsible for the protocol and must be listed as

the Principal Investigator and sign the declaration page.



For more information:









UNCA IACUC Form 6/3/05 1

University of North Carolina at Asheville



INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE

ASSURANCE OF ANIMAL CARE FORM



Office Use Only:



IACUC PROTOCOL NO USDA PAIN CLASSIFICATION: C / D / E

(CIRCLE ONE)



DATE RECEIVED: APPROVAL DATE:



RENEWAL MONTH: FIRST ANNUAL RENEWAL DATE:

SECOND ANNUAL RENEWAL DATE:







Title of Project/Course (Include Course Number):





NEW SUBMISSION

THREE YEAR MANDATORY RE-WRITE

MAJOR MODIFICATION TO EXISTING PROTOCOL #



Approx. Starting Date: Completion Date: Ongoing



Name of Funding Source Grant Deadline (if applicable):





I. RESEARCH STAFF

Principal Investigator or Course Director:



Phone #: E-mail:



College/Department/Institute:









UNCA IACUC Form 6/3/05 2

PERSONNEL QUALIFICATIONS:



List all personnel involved with the animal component of this project and their qualifications. You

should include principal investigator, co-investigator, research technicians, teaching assistants,

graduate students, undergraduate students, student hires, etc. Indicate the most recent date these

individuals have completed the web-based formal training course: Principles of Humane Animal Care

and Use. Add as many personnel to this list as necessary. Please duplicate sections as necessary.

Name: Degree(s):

Role(s) on Project:

UNCA or outside University/Agency affiliation:

Completed UNCA Formal Training? YES NO

If No please indicate anticipated date of completion or other source of training in past 5 years

Brief Outline of Experience (limit to how it applies to your activities on this project):





Name: Degree(s):

Role(s) on Project:

UNCA or outside University/Agency affiliation:

Completed UNCA Formal Training? YES NO

If No please indicate anticipated date of completion or other source of training in past 5 years

Brief Outline of Experience (limit to how it applies to your activities on this project):







Name: Degree(s):

Role(s) on Project:

UNCA or outside University/Agency affiliation:

Completed UNCA Formal Training? YES NO

If No please indicate anticipated date of completion or other source of training in past 5 years

Brief Outline of Experience (limit to how it applies to your activities on this project):









UNCA IACUC Form 6/3/05 3

II. THE ANIMALS & PROCEDURES USING ANIMALS

ANIMAL SPECIES AND STRAIN NUMBER USED AT TOTAL SOURCE OF ANIMALS

ONE TIME (PER YEAR)









CLASSIFICATION OF PROJECT:



RESEARCH/TEACHING ON VERTEBRATES IN A FIELD SETTING ONLY



RESEARCH/TEACHING ON VERTEBRATES HOUSED IN A LABORATORY OR CAPTIVE SETTING ONLY



USE OF VERTEBRATES IN BOTH A FIELD AND HOUSED IN A LABORATORY SETTING



AGRICULTURAL RESEARCH



IS THIS PROTOCOL BEING REVIEWED BY ANOTHER INSTITUTION’S OR AGENCY’S IACUC?



YES NO



IFYES PLEASE PROVIDE US WITH A COPY OF THE FINAL LETTER OF APPROVAL AND A CONTACT

PERSON FOR THAT COMMITTEE



PERMITS:



PERMITS ARE NEEDED: YES No



LIST PERMITS NEEDED



THE PI MUST APPEND A COPY OF ALL RELEVANT PERMITS (ADF&G, USF&WS, MMPA, CITES, USDA

IMPORT/EXPORT, ETC.) TO THIS ASSURANCE OF ANIMAL CARE FORM PRIOR TO STARTING THIS PROJECT.









UNCA IACUC Form 6/3/05 4

PURPOSE OF STUDY: Incomplete or unanswered questions will cause this Assurance to be returned.



A) PURPOSE OF ANIMAL USE RESEARCH TEACHING DIAGNOSTIC



B) TYPE OF EXPERIMENT NON SURVIVAL SURVIVAL BOTH



C) OBJECTIVES: In 500 words or less, how would you explain to a non-scientist, the specific

objective(s) of your project or class? Explain how your proposed animal use procedures allow you

to accomplish these objectives. Please explain how this project benefits human health, animal health

and/or how this project will provide a return of knowledge and understanding applicable to the

species or biological process under study.







D) Justify the following:



Rationale for the use of animals: [Why must animals be used rather than cell cultures,

computer models, cadavers, etc.? If this is a field study you may indicate that you are evaluating

certain biological features of a species or population.]







Appropriateness of species to be used: [Briefly describe the biological characteristics of the

animal species selected that justifies its use in the proposed study/class. Cost should not be used

as a justification, except as a means to choose among species that are equally well-suited for the

proposed project. If this is a field study please explain why this work will benefit the particular

species or population under study.]







Basic scientific methodology/research design and number of animals to be used: [How did

you determine the number of animals required? When possible include a statistical power

justification of the group size(s) or a yield of tissue needed per animal. For complex studies,

including a flow chart or table showing group sizes, time frame, etc. may be helpful in

understanding how the total number of animals was determined. Basic scientific methodology

and research design goes here but details of animal use procedures must go below. Be sure to

include a description of control groups.]









UNCA IACUC Form 6/3/05 5

REPLACEMENT, REFINEMENT AND REDUCTION:

1) The Animal Welfare Act and Public Health Service Policy require that the principal investigator

consider alternatives to procedures that may cause more than momentary or slight pain or

distress to the animal. Have you done so?



Yes No



2) You must provide a written narrative description of the methods and sources used to determine

that this work does not:



a. unnecessarily duplicate previous research,



b. that procedures are the most refined possible,



c. that you have considered alternatives to procedures that may cause more than momentary

or slight pain or distress to the animal.



This narrative description must provide details on the methods you used and sources consulted to

determine that alternative procedures are not available or acceptable. Examples of sources might

include a literature search, review of scientific journals, discussion with colleagues, etc. As a

minimum, the database(s) used to search the literature and keywords used MUST be listed and

results noted or attached.









UNCA IACUC Form 6/3/05 6

STUDY AREAS:

A) Field Study: [If applicable, please describe the location of your field study with anticipated

boundaries. If animals are to be held for brief periods you must describe the temporary holding facilities

that you intend to use, the time the animals will spend here, and your animal care protocol. If field

surgery is planned you must also complete the section on Animal Surgery Information.]







B) Housing of Animals: [Complete section B only if applicable]



Will animals be taken to a laboratory/study area outside the established animal housing facility?



YES NO



If yes, list the building name: and room number:



List procedures to be performed in this area:



Will animals taken to this area be maintained for longer than 12 hours? Yes No



If yes give the total length of time animals are to be held and explain why they must be

maintained in this area rather than being returned to the animal facility [If an animal is

maintained in an area for more than 12 hours it will be classified as a satellite facility and is

subject to IACUC and possibly USDA inspection.]







C) Husbandry: [If animals are to be held for > 12 hours, provide details of their care. Information to

be covered include feeding regime and amount, cage design and cleaning schedule, methods for

ensuring health, well being, and safety. Details of any veterinary care should be in the next section]







VETERINARY CARE OF ANIMALS: [Indicate the individual / organization you are using to

provides veterinary support and care to live vertebrates used in research and teaching. Please provide

the name(s) of veterinarian(s) providing medical care to your animals (emergencies, illness, and

preventative medicine). This section may not be applicable to field studies unless invasive procedures

are planned. Captive housing of fish does not necessarily require a veterinarian; however, you must

provide a description of your fish health program and identify the diagnostic facility to be used in case

of a fish mortality event. Do not leave this area blank! If it is a field study not requiring veterinary care

then type in “Not Applicable” – you will be notified if the committee disagrees.]









UNCA IACUC Form 6/3/05 7

ANIMAL USE PROCEDURES:

CHECK YES OR NO TO EACH QUESTION (HINT: DOUBLE CLICK ON THE BOX) AND ADD THE NEEDED

INFORMATION BELOW THE APPROPRIATE SECTION. EXPECTED INFORMATION IS EXPLAINED IN ITALICS.

SOME PROTOCOLS MAY REQUIRE INFORMATION NOT SPECIFICALLY LISTED HERE. PLEASE ENSURE THAT

ALL INFORMATION NEEDED TO EVALUATE YOUR PROTOCOL IS PROVIDED. IF YOU ARE PLANNING ACTIVITIES

NOT LISTED BELOW PLEASE ADD A SECTION TO ACCOUNT FOR ALL PROCEDURES EXPECTED TO BE DONE ON

ANIMALS.



YES NO



BLOOD SAMPLING [Describe techniques, sites of collection, volumes per sample,

frequency of sampling(s), total samples per animal, length of time animal maintained for

sampling, indicate the % blood loss per week based on the animal’s body weight and, if

applicable, describe how animal(s) will be monitored for anemia.]



URINE/FECES SAMPLING (FROM LIVE ANIMALS ONLY) [Indicate method and for all

methods indicate the length of time the animal is maintained for sampling(s). For

metabolic cages, describe dimensions of cage and time animal is housed in cage. For

catheterization describe frequency of sampling(s). For cystocentesis describe technique,

frequency of sampling. For manual expression describe technique and frequency of

sampling(s).]



OTHER BODY FLUIDS AND TISSUE SAMPLING (FROM LIVE ANIMALS ONLY) [Indicate the

type of substance, e.g. CNS fluid, abdominal fluid, bone marrow; method of collection;

volumes per sample; frequency of sampling(s); length of time animal is maintained for

sampling; total samples per animal.]



NECROPSY OR TISSUE COLLECTION FROM EUTHANIZED OR KILL TRAPPED ANIMALS [If the

sole purpose of euthanizing or kill trapping is to obtain biological samples from the

animal please indicate what you are collecting for your study. Ensure that this matches

objective statements and that the section on euthanasia and/or wildlife trapping is

complete. Ensure that all other appropriate sections are completed. ]



SPECIAL DIETS [Will food items other than standard commercial chows, feed plant

formulations/supplements, hay/grasses, etc. be used? If yes, describe diet, duration of

use, anticipated nutritional deficit/adverse effect, weight monitoring of animal(s), amount

of weight loss that will be allowed, monitoring protocol/schedule for effects.]



FOOD AND/OR WATER DEPRIVATION [Describe duration, frequency of deprivation,

reason(s) for deprivation, monitoring protocol of animal(s), amount of weight loss that

will be allowed, anticipated deficit/adverse effect, monitoring protocol/schedule for

effects.]



APPLICATION OF UNUSUAL ENVIRONMENTAL CONDITIONS [Describe condition applied

(extended darkness, cold, heat, altitude, etc.) duration, frequency, monitoring protocol of

animal(s), anticipated deficit/adverse effect, monitoring protocol/schedule for effects.]



TAGGING, MARKING, PLACEMENT OF INDWELLING CATHETERS OR IMPLANTS [Describe

type, size, duration of use, maintenance and monitoring protocol/schedule. For free-

ranging wildlife please indicate if the tag or mark might affect the animals mobility or

UNCA IACUC Form 6/3/05 8

increase the likelihood of predation. If implantation requires a surgical protocol please

mark yes to this question and complete the section on Animal Surgery Information.

NOTE: INSERTION OF PIT TAGS DOES NOT CONSTITUTE SURGERY SO YOU

NEED ONLY FILL OUT THIS SECTION IF YOU ARE USING THIS METHOD OF

MARKING]



ADMINISTRATION OF ANESTHETICS [If associated with a surgical procedure please

indicate and refer to the Animal Surgery Information section. You are not required to

provide this information twice. Describe agent, dose (mg/kg), route of administration,

duration of anesthesia, method of monitoring anesthesia; maintenance/monitoring

procedures to ensure normal body temperature is maintained in the animal, procedures

employed in case of anesthetic emergency over-dose, monitoring protocol to ensure

animal’s complete recovery from anesthesia; if by inhalation describe the equipment

used and state the method of scavenging waste anesthetic gas/fumes; if injectable

agent(s) are not commercially prepared and sterility guaranteed please describe method

used to assure the agent’s sterility when injected.]



ADMINISTRATION OF ANALGESICS [Describe agent, dose (in mg/kg), route of

administration, frequency, duration of use. If associated with a surgical procedure please

indicate and refer to the Animal Surgery Information section.]



ADMINISTRATION OF DRUGS, TOXINS, REAGENTS, CELLS, ETC. (OTHER THAN ANESTHETICS,

PARALYTICS, OR ANALGESICS) [Describe agent, dose (i.e. mg/kg), diluent, route of

administration, list equipment used for administration - e.g. gavage needle, stomach tube,

cerebral cannula, venipuncture, etc., frequency of administration, length of time animal

maintained, anticipated deficit/adverse effects, monitoring protocol/schedule for effects.

State if no adverse effects are anticipated. Describe monitoring procedures to ensure cell

lines have been screened for rodent pathogens. If injectable agent(s) or silastic

implant(s) are not commercially prepared and sterility guaranteed please describe

method used to assure the agent’s sterility when injected. If treatments are applied to an

immature egg/embryo will it be allowed to grow into the mature animal state? If YES

describe any anticipated effects to the mature animal.]



USE OF CONTROLLED AND/OR PRESCRIPTION SUBSTANCES [If obtaining these substances

through the UAF Veterinary Services Pharmacy you must contact the Attending

Veterinarian – no pharmaceuticals will be dispensed unless their use is described in this

Assurance. Irrespective of source, describe arrangements for use, ordering, record

keeping, storage, and precautions taken to avoid unauthorized access.]



VERTEBRATE HANDLING AND RESTRAINT PROCEDURES [Describe method, duration,

equipment used, dimensions of equipment if applicable, observation schedule during

confinement. Please provide detailed justification and protocol if animals are to be

physically restrained for longer than 1 hour at a time.]



PHYSICAL METHODS OF CAPTURING WILDLIFE INCLUDING TRAPPING, SNARING, HERDING,

BAITING, CORRALS, OR NETTING (INCLUDES SURVIVAL AND/OR KILLING TECHNIQUES)

[Describe equipment used, duration of restraint, monitoring protocol/schedule for

capture technique used, potential for capturing non-target species, disposition of

captured animals. You must provide a protocol for dealing with injured target or non-

target animals. If anesthesia or immobilization is also planned please refer to those

sections of this form.]



UNCA IACUC Form 6/3/05 9

CHEMICAL CAPTURE OF FREE-RANGING VERTEBRATES (IN ADDITION TO OR OTHER THAN

USE OF PHYSICAL CAPTURE TECHNIQUES) [Describe equipment used including method of

approaching the animal (i.e. helicopter, snowmachine, etc.) projectile systems for

administering drugs, etc. If physical capture techniques are also employed please

describe them above. See “Administration of Anesthetics” above for additional

requirements for describing the drugs used.]



ANIMAL TRANSPORTATION [Describe how animals are procured and transported to the

animal housing facility or between sites in the field. If animals are transported on

campus, describe method used and care that is provided to the animals while in

transport. If translocating or transporting wildlife or game species please provide full

details.]



BEHAVIORAL/OBSERVATIONAL TESTING OR STUDY (WITHOUT SIGNIFICANT RESTRAINT OR

NOXIOUS STIMULI) [Includes most field studies conducting basic observational research.

Describe procedure.]



NON-SURVIVAL SURGERY [If YES, complete Animal Surgery Information]



SURVIVAL SURGERY [If YES, complete Animal Surgery Information]



ARE YOU PLANNING ANY OF THE FOLLOWING? IF SO, PLEASE CONTACT THE IACUC FOR

INSTRUCTIONS.



ADMINISTRATION OF PARALYTICS



ADMINISTRATION OF INFECTIOUS ORGANISMS



ADMINISTRATION OF RADIATION TREATMENT



ANTIBODY PRODUCTION (POLYCLONAL OR MONOCLONAL)



BEHAVIORAL TESTING (WITH SIGNIFICANT RESTRAINT OR NOXIOUS STIMULI)



DEATH AS AN ENDPOINT (LD 50 or similar studies)





WILL ANY PROCEDURES CAUSE MORE THAN MOMENTARY OR SLIGHT PAIN/DISTRESS?

[Complete the following and describe measures taken to alleviate adverse effects. What

methods are used to estimate presence or degree of pain/distress? If no measures are

taken you must PROVIDE SCIENTIFIC JUSTIFICATION.]

EXPECTED PAIN/DISTRESS LEVEL NIL LOW MODERATE HIGH



DEFINITIONS FOR PAIN LEVELS CAN BE FOUND AT

DISCOMFORT IS EXPECTED DURING PROCEDURE



POST PROCEDURE - DURATION:









UNCA IACUC Form 6/3/05 10

III. BIOHAZARDS

WILL YOU HOUSE ANIMALS IN AN ANIMAL HOUSING FACILITY OR RELEASE ANIMALS INTO THE WILD AFTER

THEY HAVE BEEN GIVEN AGENTS THAT MAY BE HAZARDOUS TO HUMANS OR OTHER ANIMALS?



YES NO



If yes indicate the type of agent:

AGENTS: CARCINOGENS ISOTOPES INFECTIOUS CHEMICAL OTHER



LOCATION OF ROOM WHERE ANIMALS WILL BE HELD:



Describe the agent, type of hazard, amount and route of administration, frequency of administration,

route of excretion, anticipated deficit/adverse effects on treated animals, monitoring protocol/schedule

for affected animal. If previously described under animal used procedures please indicate. Rooms, pens,

and/or paddocks must be properly marked and staff informed.







IF USING BIOHAZARDS, YOU MUST ALSO FILL OUT EHS FORM







IV. ANIMAL SURGERY INFORMATION

Check here if no surgery is planned. If no surgery planned, go to section V.







SPECIES USED NUMBER USED S=SURVIVAL BUILDING AND ROOM WHERE

SURGERY IS PERFORMED (INDICATE

(ADD ROWS IF NEEDED) N=NON-SURVIVAL IF THIS IS FIELD SURGERY)









PRE-OPERATIVE PROCEDURES/CARE:



a) Have unhealthy animals been exempted from surgery? YES NO



If no, explain the rationale for performing surgery on unhealthy animals.







b) Person responsible for evaluating pre-operative health status of animals.









UNCA IACUC Form 6/3/05 11

c) Provide a brief description of all pre-operative procedures and care. [Including withholding of

food and water, pre-operative antibiotic/therapeutic drug/fluid administration (agent, dose in mg/kg),

route of administration, frequency, duration of treatment, preparation of surgical site (e.g. clipping, use

of antiseptic scrub/solution, etc.)]







ANESTHETIC PROCEDURES:



a) Provide a brief description of anesthetic procedures. [Describe agent, dose (i.e. mg/kg or % if by

inhalation), route of administration, expected duration of anesthesia, monitoring procedure to evaluate

depth of anesthesia; maintenance/monitoring procedures to ensure normal body temperature is

maintained in the animal, procedures employed in case of anesthetic emergency over-dose, monitoring

protocol to ensure animal’s complete recovery from anesthesia; if by inhalation describe the equipment

used and state the method of scavenging waste anesthetic gas/fumes; if injectable agent(s) are not

commercially prepared and sterility guaranteed please describe method used to assure the agent’s

sterility when injected.]







b) Identify the individual(s) performing and monitoring anesthesia.







SURGICAL PROCEDURES:



a) Provide a brief description of all surgical procedures to be performed. [Include site of incision,

procedures performed, anticipated duration of procedure, method of wound closure including type and

size of suture/staples.]







b) Describe procedure employed to ensure aseptic technique is maintained through out surgical

procedure. [Describe sterilization method used for instruments, equipment and supplies; indicate the

use of sterile gloves, gowns, drapes, mask, cap, sterile implants, sterile suture/closure material. Since

gowns are not required for rodent surgery please indicate the clothing to be worn during surgery. If

same surgical instruments are used for multiple animals (i.e. rodents), describe how the instruments are

managed to assure continued sterility.]







c) Identify all individuals performing surgery.







POST-OPERATIVE PROCEDURES/CARE:



a) Provide a brief description of all post-operative procedures and care. [Include criteria to assess

animal pain and the need for analgesics, type of post-operative analgesics (describe agent, dose, route

of administration, frequency, duration of treatment); techniques used to ensure maintenance of normal

body temperature in the animal; incision care, monitoring and time of suture removal; catheter or long

term care of any chronically instrumented/implanted animals, monitoring and time of removal;

bandage/dressing monitoring and changing schedule.]

UNCA IACUC Form 6/3/05 12

b) If post-operative analgesics will not be used, PROVIDE SCIENTIFIC JUSTIFICATION.







c) Describe arrangements for post-operative monitoring of animals, the individual(s) responsible

for performance of monitoring, including after-hour, weekend and holiday care.







d) Describe the use of any antibiotics or other therapeutic drugs. [Describe agent, dose (i.e. mg/kg,

IU/kg), route of administration, frequency, duration of treatment.]







e) If this surgical procedure induces a disease or other functional alteration, describe any

anticipated adverse effects and deficiencies, monitoring protocol/schedule for animals, animals’

degree of tolerance to disease/functional deficit.









MULTIPLE SURGERIES:



Will animals be subjected to more than one (1) survival surgery?



YES NO



If yes, provide scientific justification and explain how surgeries are related. [A major operative

procedure is one that enters a body cavity. You must provide additional justification to perform multiple

major operative procedures on one animal. Removal of telemetry devices is an acceptable reason.]









V. EUTHANASIA AND DISPOSAL

ALL METHODS OF EUTHANASIA MUST FOLLOW THE AVMA PANEL ON EUTHANASIA (Journal of the

American Veterinary Medical Association Vol. 218, No.5 March 1, 2001, pages 669-696. Accessible

from the IACUC web site http://www.uaf.edu/iacuc/). ANY DEVIATIONS MUST BE SCIENTIFICALLY

JUSTIFIED.



PLEASE DESCRIBE THE METHOD PLANNED. IF BY CHEMICAL AGENT YOU MUST IDENTIFY THE COMPOUND

AND SPECIFY THE DOSE (mg/kg) AND ROUTE OF ADMINISTRATION. PHYSICAL METHODS (CERVICAL

DISLOCATION, DECAPITATION) MAY BE USED ONLY AFTER OTHER METHODS HAVE BEEN EXCLUDED AND

WHEN SCIENTIFICALLY JUSTIFIED.









UNCA IACUC Form 6/3/05 13

DESCRIBE METHOD USED TO ENSURE THE ANIMAL WILL NOT REVIVE (e.g. removal of heart, induction of

bilateral pneumothorax, observation of rigor mortis, etc.)







EVEN IF YOU DO NOT INTEND TO EUTHANIZE ANIMALS AT THE COMPLETION OF YOUR PROJECT, A METHOD

OF EUTHANASIA SHOULD BE LISTED IN CASES OF EMERGENCY OR YOU ARE UNABLE TO SELL/TRANSFER

THESE ANIMALS.









IF ANIMALS ARE NOT EUTHANIZED PLEASE INDICATE THEIR DISPOSITION [e.g. transferred to another

project/class - indicate new project, IACUC # and investigator. OTHER - please describe.]









UNCA IACUC Form 6/3/05 14

VI. DECLARATION: The information on this Assurance of Animal Care Form is an accurate

description of my animal care and use protocol(s). All people using animals have been properly trained

to use appropriate methods and have read and agree to comply with this protocol. All individuals

working under this Assurance will comply with the procedures and methods outlined in NIH Guide for

the Care and Use of Laboratory Animals, as well as PHS Policy, The Animal Welfare Act, and

applicable University Policies. All field research will be carried out in accordance with the principles

outlined in Acceptable Field Methods of Mammalogy, Guidelines for the Use of Wild Birds in

Research, Guidelines for the Use of Fishes in Field Research, and/or Guidelines for the Use of Live

Amphibians and Reptiles in Field Research. All use of animals in agricultural research or teaching will

comply with the procedures and methods outlined in the Guide for the Care and Use of Agricultural

Animals in Agricultural Research and Teaching. All work proposed herein is the most refined possible

to avoid or minimize discomfort, distress, and pain to the animals; does not unnecessarily duplicate

previous experiment; and non-animal alternatives have been considered.





Principal Investigator or Course Director Date







VII. APPROVAL:

Final Approval - Chairman, Institutional Animal Care and Use Committee



Date









UNCA IACUC Form 6/3/05 15



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