TOTAL LEAKY GUT:
                                         Product # 2703
                     (Researched by and formulated for Dr. John Brimhall)

Each tablet supplies: L-Glutamine 150mg, N-Acetyl Glucosamine 75mg, Buffered Vitamin C
(Sago Palm) 25mg, Vitamin E Succinate (natural) 10 i.u., Lipoic acid 2mg, Cats Claw 15mg,
Gingko Biloba Herb 50mg, Deglycyrrhizinated Licorice Root 50mg, Jerusalem Artichoke 25mg,
Slippery Elm 100mg, Zinc Chelate 5mg, Lactobacillus Acidophilus 1 million units, Lactobacillus
Bifidus 1 million units.

Recommendation 1 to 2 tablets, 3 x day or as directed.

                                 The Leaky Gut Syndrome:

                                       By Dr. Lynn Toohey

Newsweek focused on an article recently called, “Gut Reactions”, in which they reported
that tiny leaks in the lining of small intestine may play a role in diseases as diverse as
asthma and arthritis (Newsweek, November 17, 1997. P. 95-99). What is happening is a
new awareness of one of the oldest immune weapons we have - our own gut lining! The
lining of our intestine is meant not only to absorb food, but also to act as a barrier to keep
out invading pathogens. Newsweek calls it, “Intestinal Fortitude”, where the mucosal
layer of a healthy gut filters out microorganisms and undigested proteins. When things
like aspirin, bacteria, or even the pesticides sprayed on our food batter this lining, the
lining loses its integrity. This is when the door is opened to let in the bacteria, the
viruses, and the parasites - (even undigested food molecules) which can activate the
immune system (and also the autoimmune system). We refer to this loss of integrity as
“the leaky gut syndrome”.

There are many symptoms related to leaky gut, some of which would not initially even
come to mind as being a result of permeability. Some of these symptoms include:
fatigue, arthralgia, myalgia, fever, abdominal discomfort, diarrhea, skin rashes, toxic
feelings, memory deficit, and shortness of breath (Leo Galland, MD).

No disease needs to be present to warrant protecting the intestinal lining; keeping this
“immune barrier” healthy helps to keep us strong and disease-resistant People who
smoke, drink, take aspirin/ibuprofen/antibiotics/drugs, get exposed to environmental
toxins, have poor digestion, sluggish liver detoxification, or stored toxins, or who have
bacterial/microbial infections or inflammation, are at high risk for intestinal permeability.

Glutamine is the main fuel that the intestinal cells need for maintenance and repair (they
slough off every three days). There is considerable evidence that glutamine can enhance
the barrier function of the gut against viral, bacterial, and food antigen invaders.
(Br J Surg 1996;83(3):305-312).

Lactobacillus bifidus are friendly bacteria, which offset populations of bad bacteria.
Overpopulation of bad bacteria can beat away at the intestinal lining. Friendly bacteria
especially counteract candida, which can spread long mycelial arms right through the
intestinal lining and perforate it, permitting wide-open entry to microorganisms and

NAG (N-acetyl Glucosamine), aside from being able to support the extracellular tissue
surrounding intestinal epithelial cells, has the unique ability to decrease the binding of
some lectins to the intestinal lining. Lectins are antinutrients found in many grains and
legumes, and in genetically susceptible people, this can cause an immune (and
autoimmune) response. Research shows that NAG is one of the few nutrients with the
power to bind to some of these lectins and prevent damage to the intestinal lining. (Int. J.
Parasitol ,1991;1-2(8): 941-944).

Vitamins C and E, lipoic acid, zinc and ginkgo biloba are all antioxidants which protect
the lining from free radical damage. Vitamin E maintains the integrity of all lipid cell
membranes. Zinc is essential for proper immune system functioning. It is believed to
play a role in regenerating epithelial tissue and protecting it from damage.

DGL (deglycyrrhizinated licorice) increases the integrity of the mucous cells - it
increases the life span of the intestinal cells, improves the quality of protective
substances, and improves blood supply of nutrients (Glick L. Lancet ii:817, 1982).
Additionally, it has a high healing rate and significantly low relapse rate for ulcers
(Kassir ZA Irish Med J 78:153-56, 1985). DGL has been found to inhibit the
helicobacter pylori bacteria responsible for ulcer formation, gastritis, and gastric cancer.
("DGL May Inhibit Helicobacter Pylori", Am J of Nat Med. 1995; 2(10):16)

Slippery elm is a soothing, protective demulcent renowned for its beneficial effects on the
gastrointestinal lining. Slippery elm helps calm the inflamed mucous membranes and
contains the fiber-rich ingredient mucilage, which stimulates mucous secretion . (Balch
JF Presc for Nutr Healing 1990, Garden City, NY).

The above statements have not been evaluated by the FDA. The nutritional information, suggestions, and research
provided are not intended to diagnose, treat, cure, or prevent disease and should not be used as a substitute for sound
medical advice. Please see your health care professional in all matters pertaining to your physical health.

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