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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=







The hearts were irradiated

IEEE Trans from the bottom of

pulsed organ

Abbate, M.; EVALUATION OF PULSED Microw the holder by using a tapered

Universita di (heartbeat medical > 10 - 40 (heart of chick, part: organ

1 Abbate, M. Tine, G.; Italy

Dipartimento di Ingegneria Elettrica, Universita di Palermo, I-90128 Palermo, Italy

1996 MW INFLUENCE ON Theory Tech 2.45 2.45 none 2.3 2.3 nn nn nn /3 nn nn nn near-field acute continuous 0 nn nn

Palermo frequency application open coaxial section improved minutes 9 - 12 day old heart (cardio-vascular)

Zanforlin, L. ISOLATED HEARTS 44 with a matching

modulated) embryos)

(10 pt. 2) set-up.









PARTIAL-BODY EXPOSURE

OF HUMAN VOLUNTEERS 1 exp: 3

Adair, E. R.; Bioelectro- horn antenna 6 (36-68 yr

AFRL/HEDR, TO 2450 MHz PULSED OR 27; 27; /5,94; clearly males, pw;

2 Adair, E. R. Mylacraine, K. S.; AFRL/HEDR, 8315 Hawks Rd., Bldg. 1162, Brooks AFB, TX 78235-5324, e-mail:eleanor.adair@he.brooks.af.mil (RR/E.R.A., B.L.C.); Veridian, Inc.,65

USA 2001 magnetics 2.45 2.45 none 10000 10000 65 Brooks AFB, TX (K.S.M.)

pulsed nn nn cw = pw nn Cober Electronics model far-field 45 minutes acute continuous 1 human olsd) + 7 (41- whole body thermo-regulatory

Brooks AFB CW FIELDS PROVOKES 35 35 /7,7 above 2exp: 5 males

Cobb, B. L. 22(4) 6823 Klystron amplifier 68 yr old)

SIMILAR cw

THERMOREGULATORY

RESPONSES









EFFECT OF EM RADIATION

IN DECIMETRE Biophysics cell

Alekseev, S. I.; below /

USSR Academy WAVELENGTH (Engl Transl 0,5 - pulsed (neurones of the cell

3 Alekseev, S. I. Il'in, V. I.; Tyazhelov, USSR

Instit. of Biological Physics, USSR Academy of Sciences, Pushchino (Moscow Region), USSR

1987 0.9 0.9 none 0.5 nn nn nn nn 0,2 - 20 cw = pw close to / nn waveguide chamber near-field 10 minutes acute continuous 0 nn nn cell

of Sciences RANGE ON CALCIUM Biofizika) 1000 (AM) nerve ring of (nervous)

V. V. above

CURRENT OF MOLLUSK 31(2) Limnea stagnalis)

NEURONES









1;

6;

Philippova, T. M.;

MW EFFECT ON CAMPHOR Bioelectro- 16; below / cell

Novoselov, V. I.; USSR Acad. of nn 0,5 - 18 standard waveguide cell: cell

4 Alekseev, S. I. Physics,

Inst. of Biological USSR USSR Acad.BINDING TO142292 Pushchino, Moscow Region, USSR (RR/T.M.P.)

1988 of Science, RAT magnetics 0.9 0.9 none 1 32; nn nn pulsed nn cw = pw close to / nn near-field nn nn nn 0 (olfactory tissue of nn nn

Bystrova, M. F.; Science olfactory tissue (sensoric)

OLFACTORY EPITHELIUM 9(4) 50; above rat)

Alekseev, S. I.

75;

100









1;

Influence of MW on different 6;

Philippova, T. M.; Russian Bioelectro- below / cell

types of receptors and the role 16; pulsed nn e.g. nn cell

5 Alekseev, S. I. Novoselov, V. I.; Academy of Institute of Cellular Biophysics, 1994

Russia Russian Academy of Sciences, Puschino, Moscow Region.0.9

magnetics 0.9 none 1 nn nn nn 0,5 - 18 nn close to / nn nn e.g. 15 min acute continuous 0 (hippocampus; liver nn nn cell

of peroxidation of lipids on 32; (rectangular) 1,0 (nervous, digestive)

Alekseev, S. I. Sciences 15(3) above of rat)

receptor-protein shedding 75;

100









1;

4;

bilayer lipid

8;

Temple Univ. MILLIMETER MW EFFECT membranes

Bioelectro- 53 - 78 12; rectangular

Alekseev, S. I.; Medical Sch.; ON ION TRANSPORT pulsed clearly (formed from

6 Alekseev, S. I. USSR Temple Univ. Medical Sch., 3400 N. Broad St., Philadelphia, PA19140 (RR/M.C.Z.); Inst. of Cell Biophysics,nn

Center for Biomedical Physics,1995 magnetics 54 76 (1 GHz 1 16; Acad. of Sciences, Pushchino, Moscow Region,142292 Russia (S.I.A.)

Russian nn / 0,02 nn 2000 cw = pw nn nn 5 minutes acute continuous 0 nn nn model system physical model system

Ziskin, M. C. Russian Acad. ACROSS LIPID BILAYER (square) above waveguide outlet phosphatidylcholine

16(2) step) 32;

of Sciences MEMBRANES. and cholesterol in

60;

decane)

100;

1000









A. N. Marzeev

"P-37" 30 or 45

Research Inst. 0,01; rat organ (endocrine);

Antipenko, E. Antipenko, E. N.; CYTOGENETIC EFFECTS Dokl Biol Sci 2,375 2,75 close to / "Luch-58" apparatus in days

7 of General and USSR

A. N. Marzeev Research Inst. of General and Communal Hygiene, Kiev, USSR

1988 none 300 300 2.7 2.7 pulsed nn 0,05; nn cw = pw nn nn temporary intermittent 0 (3-5 mo old male nn whole body cell

N. Koveshnikova, I. V. OF MW OF NONTHERMAL 296(3) (CW) (PW) above apparatus an anaechoic for 7

Communal 0,5 mongrel) (digestive)

INTENSITY IN MAMMALS chamber hours/day.

Hygiene









45 days,

A. N. Marzeev

CHANGES IN BODY 0,01; 7h/d (2.375

Res. Inst. 0,01; rat

Antipenko, E. Koveshnikova, I. V.; WEIGHT OF RATS DURING Radiobiologiia 0,546 2,75 2,375 0,05; above / "Luch-58" GHz and

8 General and USSR

A. N. Marzeev Res. Inst. General and Communal Hygiene, Kiev, USSR

1988 nn nn nn nn pulsed nn 0,05; nn cw = pw nn P-37 device nn temporary intermittent 0 (random-bred female, male nn whole body whole organism

N. Antipenko, E. N. IRRADIATION WITH MW OF 28(4) (PW) (PW) (CW) 0,06 close to apparatus 2.750) and

Communal 0,06 albino)

NONTHERMAL INTENSITY 14 hours/day

Hygiene

(546 MHz)









Marzeev

THE PARTICIPATION OF rat

Scientific Res. organ (endocrine);

Antipenko, E. Koveshnikova, I. V.; THYROID HORMONES IN Radiobiologiia 2,45 2,75 7 hours/day, (mature, white

9 USSR

Marzeev Scientific Res. Inst. of General and Communal Hygiene, Kiev, Ukraine

Inst. of General 1991 none 400 400 2.7 2.7 pulsed nn 0.5 nn cw = pw above nn nn nn temporary intermittent 0 nn nn whole body cell

N. Antipenko, E. N. MODIFYING THE 31(1) (CW) (PW) 30 days mongrel,

and Communal (digestive)

MUTAGENIC EFFECT OF MW 3 mo-old)

Hygiene









CAN ELECTROMAGNETISM

0,22 -

Balanovski, E.; ACCOUNT FOR Nature 0,001; tuneable RF source;

10 Balanovski, E. Dept. Mathematics, King's Coll., London WC2, UK

King's Coll. UK 1978 0.22 17 0,95; nn nn nn nn pulsed nn nn cw = pw nn nn nn nn nn nn 1 human nn nn whole body whole organism

Taylor, J. G. EXTRASENSORY 276(5683) 0,005 tuneable MW source

6 - 17

PHENOMENA?

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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



Previous no heartbeat modification; cardiac frequ. shifted Therefore, the authors concluded dragging phenomena of MWs: nn nn ´-(heartbeat ´-(heartbeat

experiments towards pulse rep. rates but maintained its that any heartbeat increase was based on effects on the modification) modification); ↕+

showed that characteristic frequency distribution; not related to temperature sodium-potassium and (dragging effect)

applied modulated variations. Dragging and sodium-calcium exchange

microwaves (MWs) regularization effects, observed processes.

heart frequency (instantaneous, external could capture and when

dragging effects, MW regularization fix Ringer no EXP CVS in vitro entrain the beat of organ function no -/- nn the samples were irradiated for

effects), interbeat fluctuations solution an isolated chicken short periods, appeared during

embryo heart when longer irradiation periods as well

the modulation and lasted through the entire

frequency was exposure time.

slightly faster than

Tes- at the the authors

Theunperturbed Minimal changes in Tes and MHP; no reliable The authors concluded that partial nn sham exposure nn ´- (Tes); ↕+ (Tsk) ´- (Tes); ↕+ (Tsk)

subjective judjements; deep body atrium of examined differences between the effects of CW and PW body exposure of adult humans to

temp(Tes) and average skin temp the heart; thermoregulatory irradiation; Tes did not exceed 0.1 C, which falls CW or PW 2,450-MHz RF

(Tsk) (Luxtron probe).; Tsk- at responses of within the variability range of the Luxtron probe. radiation does not stimulate

ventral humans to partial- Local Tsks showed similar power density dependent increases in Tes. As was the case

Metabolic heat production(MHP) yes at upper body trends for CW and PW irradiation with only one in two previous studies (Adair et al.

(oxygen and carbon dioxide fixed thigh, left RES; in vivo irradiation with exception. The Tsk measured at the upper back 1998 and 1999), the magnitude of

yes EXP thermoregulation no -/- nn

fractions in expired air); ambient upper TMP probands pulsed wave (PW) (facing the antenna) was significantly greater during the measured thermophysiological

T° chest, or continuous wave PW than during CW irradiation. Local sweat rates responses was power density-

local skin blood flow(SkBF) ventral left (CW) and SkBFs were both Ta- and power density- dependent and related to the

(Dopplerflowmeters); forearm, radiofrequency dependent, and showed greater inter-subject prevailing thermal environment.

left upper (RF) radiation. variability than other measures between CW and There is no clear evidence for a

local sweating rates back, Two experiments PW exposure. The subjective judgments made differential response to CW and

central were conducted, during the experiments generally matched measured PW RF radiation. Experiments

A number of Increase in the calcium current were proportional to The temperature The authors calculated the heating nn nn nn ↑+ (calcium current) ↑+ (calcium current)

studies have the SAR only and did not depend on the parameters change values effect of MWF exposure in

suggested that of modulation. A solution flow speed of 2-3 ml/min computed from the comparison to the temperature

calcium flux in abolished any significant response to microwave increment of calcium coefficient (Q10) of the calcium

neural tissue may radiation. current somewhat current, and concluded that the

be very sensitive to exceed the effects of MWF can be attributed

intracellular dialysis to the effects of experimental value for to a thermal effect.

external BMP; amplitude- the change in

follow the calcium current of fix yes EXP in vitro membrane function no -/-

solution CEF modulated, low- temperature which

mollusk neurones

intensity might indicate

microwave fields selective overheating

(MWF). In an of the cells in the

attempt to isolate MWF, but is more

the specific likely only the

components of the consequence of

MWF effect, the measurement errors.

In order to assess MW irradiation markedly decreased specific 3H- The authors conclude that ligand Mechanism for MW binding nn nn ↓++(specific ligand ↓++(specific ligand

possible effects of camphor binding in membrane suspensions while binding inhibition occurs only in inhibition: the formation of field binding) binding)

an electromagnetic nonspecific 3H-camphor binding was not affected. intact membranes in this model. gradients within the ´- (non-specific ligand ´- (non-specific ligand

field on ligand Inhibition of 3H-camphor binding was not modulation- heterogenous regions of the binding) binding)

binding of camphor to the isolated binding to receptor frequency dependent and was not a linear function membranes activates some

BMP; elements, the of SAR. The mean reduction was 44.9% at a SAR membrane enzymes which

membrane fraction of olfactory fix nn no EXP in vitro membrane function no -/- none

SEN effects of of 3 W/kg. Receptor binding inhibition was the induce shedding of specific

epithelium

microwave (MW) same at control temperatures of 10, 20, and 37 C. membrane proteins into

irradiation on solution.

the binding of

camphor to the

isolated membrane

The effects of a Binding of ligands to cell membranes was nn Enzymatic peroxidation of nn nn ↕+ (bindings of ↕+ (bindings of ligands

continuous wave or differentially affected by exposure to microwaves. lipids in localized areas of ligands to cell to cell membranes

pulse-modulated, Under the same field conditions, binding of ligands receptor binding remain a membranes were were differentially

900 MHz depends on the type of ligand and membranne. possibility for a mechanism. differentially affected) affected)

microwave field Binding is not dependent on modulation or on a

were studied by in change in the constant of stimulus-receptor binding

BMP;

binding of ligands to cell membranes nn nn nn EXP in vitro vitro assays of rat membrane function no -/- but depended on a shedding of the membrane's nn

CEF

chemoreceptors. receptor elements into solution. The magnitude

The pulsed field of inhibition correlated with the oxygen

was modulated as concentration in the exposed suspension.

rectangular waves Antioxidants (dithiothreitol and ionol) inhibited the

at rates of 1, 6, 16, shedding of receptor elements. The microwave

32, 75, or 100 pps. exposure did not cause an accumulation of

The effects of capacitance: The capacitance of unmodified BLM The authors concluded that all nn nn nn ↕+ (TPhB) ↕+ (TPhB)

millimeter waves decreased reversibly 1.2 +/- 0.5% after CW MMW-induced changes in ↕(+) (Gramicidin) ´- (Gramicidin) change (cw)

(MMW) on the irradiation (61.22 GHz, 20 mW) for 5 min. BLM membrane capacitance and

capacitance and modified by 2 different concentrations of TPhB currents

conductance of showed a reversible increase of 5 +/- 1% in the were equivalent to heating by

bilayer lipid membrane current. Similar results were obtained approximately 1.1 C, and were

membranes after irradiation for 5 min at other frequencies in the therefore

(BLM), formed from 54-76 GHz range with a 1 GHz step lead. No thermal in nature and without

physical phosphatidylcholine "resonance-like" characteristics.

capacitance; in the resonance-like effects on membrane capacitance,

fix yes EXP PHY model and cholesterol in membrane function -/- yes nn

conductance sample ionic channel currents, or TPhB transport were

system decane, was detected.

reported in this

paper. Consistent with a thermal explanation, PW and

The BLM were 10(- CW irradiation at the same average temporal

5) mm in thickness. powers effected the same changes in TPhB

Some membranes transport.Changes correlated with a temperature

were modified with rise of 1.1 +/- 0.1 C at an output power of 20 mW

gramicidin A or measured at the waveguide outlet. The rate of

amphotericin B,

A direct temperature rise was 0.48 +/- 0.04 C/sec. was

The cytogenetic effect of MW irradiation The authors suggest that it involves nn nn nn ↕+ (cytogenetic ↕+ (cytogenetic

cytogenetic effect found to vary with the intensity. Reduced a stimulation of genetic repair as a effects vary with the effects vary with the

of low-level number of aberrations at 10 or 50 uW/cm2, and an result of enhanced production of intensity; reduction of intensity; reduction of

microwave (MW) increase in aberrant hepatocytes at 500 uW/cm2. thyroid hormones. aberrations and aberrations and

number of cells with chromosomal irradiation would The mutagenic increase is equivalent to an ionizing increase in aberrant increase in aberrant

END; in vivo -> not be expected hepatocytes) hepatocytes)

aberrations (in late anaphase and nn nn nn EXP genotoxicity no -/- radiation dose of 0.5 Gy in rats of the same series. nn

GEN vitro because of the low Removal of the thyroid gland led to the loss of the

early telophase)

energy potential of antimutagenic effect of MW irradiation. The

such radiation, antimutagenic effect of MW radiation cannot be

however an explained by faster removal of damaged cells.

indirect effect may

be possible though

The effects of long- Exposure to MW resulted in growth delay throughout The authors suggest that the nn shelf control nn ↓+(body weight) ↓+(body weight)

term exposure to the entire experiment. The decrease in weight gain observed changes in body weight

microwaves (MW) was observed after irradiation with both the CW and were associated with MW-induced

body weight nn nn nn EXP GRO in vivo of nonthermal growth no -/- PW MWs at all three frequencies over the 10-60 nn stimulation of thyroid gland function.

intensity uW/cm2 PFD range. Significant differences

were studied in (p ´-(mutagenic

chromosome aberrations nn nn nn EXP white mongrel rats. genotoxicity no -/- PW and CW is enhances the mutagenic effect of nn shelf control ↑+(mutagenic effect) ↑+(mutagenic effect)

GEN vitro effect)

(HCAI) In the first series, insignificant microwaves, while normal function

animals were of the thyroid gland is an important

exposed to condition for the stabilization of

continuous 2450 chromosome integrity.

MHz microwaves

(CMW). The

animals

were divided into

Electromagnetic changes of the no indication on human sensitivity to EM radiation,

sensivity;

(EM) detectors neurological both PW and CW MW or RF, was found in humans ´- (sensitivity to low

EM emission from subjects in vivo ´- (sensitivity to low

nn nn nn EXP HYP covering a wide system; no -/- with extrasensory phenomena nn nn nn nn nn levels of EM

performing probands levels of EM radiation)

range of physiology radiation)

alleged extrasensory phenomena

Forschungsgemeinschaft Funk e.V. frequencies were Seite 2 von 100

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Werner Alsbach / Jürgen Zschernitz / Margarita Simeonova Ausdruck vom 11/16/2011

used to search for

Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn



nn athermal









nn thermal









nn thermal









nn nn









nn nn









yes thermal









nn nn









nn nn









nn nn









nn nn



Forschungsgemeinschaft Funk e.V. 2f7970c4-fa63-48a5-bb8d-bba54b3501af.xlsstudies

Seite 3 von 100

Werner Alsbach / Jürgen Zschernitz / Margarita Simeonova Ausdruck vom 11/16/2011

Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









ELECTROENCEPHALOGRAP

HIC AND MORPHOLOGICAL organ

Baranski, S.; Acta Physiol

11 Baranski, S. nn nn Poland 1967 STUDIES ON THE EFFECT 3 3 none nn nn nn nn pulsed nn 5-7 nn nn above nn nn nn nn chronic nn nn nn nn nn nn (nervous;

Edelwejn, Z. Pol 18(4)

OF MW ON THE CENTRAL thermo-regulation)

NERVOUS SYSTEM









Histological and histochemical

effect of MW irradiation on the Am J Phys

12 Baranski, S. Baranski S. nn nn Poland 1972 nn nn none nn nn nn nn pulsed nn nn nn nn nn nn nn nn nn nn nn nn nn nn nn nn whole organism

central nervous system of Med 51 (4)

rabbits and guinea pigs









RF cavity



Research

amplifier

State Univ. of (model

New York; 10W1000M7) 34 birds (133

Univ. of RESPONSES OF NEURONS driven by an zebra finches neurons) cell:

Beason, R. C.; Neurosci Lett /0,1; 0,5 nn HP 8350A cell

USA Columbus Ave., Sandusky, OH 44870 (present address/R.C.B.); Dept. ofZoology, J. W.217

v. Ave., Monroe, LA 71209, e-mail: beason@ulm.edu (RR/R.C.B.);USDA/APHIS/WS/WRC, 61002002

13 Beason, R. C. Louisiana at TO AN AMPLITUDE 0.9 0.9 none Goethe Univ., Siesmayerstrasse 70, 60054 Frankfurt a.M., Germany (P.S.)

217 nn nn pulsed nn nn nn 0.05 nn below nn nn 10 minutes acute continuous 0 (Taenopygia nn neurons of the

Semm, P. 333(3) sweep (nervous)

Monroe; MODULATED MW STIMULUS guttata) cw: 3 avian brain

J. W. Goethe oscillator neurons

Univ. with an HP

83522A RF

unit set at 900

MHz.

Amplitude

modulation of

Birenbaum L; J Microw

Kaplan IT; Power

part:

14 Birenbaum L Metlay W, Rosenthal nn nn Canada 1969 Effects of MW on the rabbit eye 4 (4); 5.5 5.5 70 nn nn nn nn pulsed nn nn nn nn nn nn nn nn nn nn nn 0 rabbit nn nn sensoric

eye

SW; IEEE Trans

Schmidt H; Biomed Eng

Zaret MM 16(1)

Birenbaum L;

MW and infra-red effects on

Kaplan IT; J Microw part:

heart rate, respiration rate and nn clearly nn cardio-vascular

15 Birenbaum L Metlay W; nn nn Canada 1975 Power 2.8 2.8 1000 1000 1.3 1.3 pulsed nn 20 20 cw = pw nn nn nn nn nn 0 rabbit nn nn entire dorsal

subcutaneous temperature of above respiratory

Rosenthal SW; 10 (1) surface

the rabbit

Zaret MM









Pacific

0,0001 -

Northwest human part:

LOW POWER RF AND MW Physiol 0,96 wire rod whole organism

Center for the 9,6 2 on -13 -10 -9 clearly open nn (men and women, torso;

16 Bise, W. Northwest USA OR 97222

PacificBise, W. Center for the Study Non-Ionizing Radiation, Box 22053, Portland, EFFECTS ON HUMAN

1978 Chem Phys 0.0001 (cw) nn nn 2 pulsed nn 10 - 10 10 nn cw pw nn "Romashka" device (Russia) nn 5 minutes acute continuous 0 nn 30,000 cell

A. Lindt, T. A.; Univ. 16; 0,12; 0,24; below (pw) Cantor S.; at (embryo)

IRRADIATION ON 41(4)

Evdokimov, E. V. 22; 0,36; 0.5 / sensitive age: 15 hr,

DROSOPHILA EMBRYOS

40 (second 10 min)

experiment)









Forschungsgemeinschaft Funk e.V. 2f7970c4-fa63-48a5-bb8d-bba54b3501af.xlsstudies

Seite 4 von 100

Werner Alsbach / Jürgen Zschernitz / Margarita Simeonova Ausdruck vom 11/16/2011

Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



Es wurde eine Die chronische Exposition bei Mikrowellen innerhalb

Reihe von EEG- des 10 cm Bandes (Leistungsflussdichte 7

und mW/cm²), die nicht die Temperatur erhöht, erzeugt

morphologischen sowohl funktionelle als auch morphologische

Untersuchungen Änderungen. Ihre Stärke nimmt zu, wenn Das Nicht-Vorhandensein

morphological/ histopathological durchgeführt, um Pulsmodulation und keine kontinuierliche Modulation erkennbarer funktioneller und

changes in brain-tissue-cuts rectal; at den Einfluss einer angewendet wird. Das Nicht-Vorhandensein einer morphologischer Änderungen nach

(Hämatoxylin-Eosin-Färbung; Nissl- the Mikrowellen- großen Wirkung einer einzelnen Mikrowellen-

morphological and Exposition bei 3 cm Mikrowellen ist

Färbung); cerebrall EOR; nn Exposition auf das Exposition (Leistungsflussdichte 5-7 mW/cm²) und

pathological ein Nachweis für die Abhängigkeit ↑+ ↑++

effects on the neurologic system yes cortex yes EXP NES; (in vivo; in -/-

Zentralnervensyste yes die gleichzeitige Verstärkung der Änderungen, wenn nn nn nn nn amplification (pw)

changes; der Wirkung von der Wellenlänge. thermal effect athermal effect

(EEG); Thermoregulation surface; TMP vitro) m zu untersuchen. die Dauer der Exposition verlängert wird, deutet auf

thermoregulation Dies wiederum scheint mit der

(Rectaltemp.; Temp. of the surface subcutaneo Es wurde der die Möglichkeit der Kumulation der angewendeten Absorption der Energie über das

of the cerebrale cortex and in us Unterschied der Dosen hin. Der negative Effekt einer einzelnen Oberflächen-Gewebe verbunden

subcutane tissue of the head) Wirkung von einem Mikrowellen-Exposition gleichwertiger Länge hängt zu sein.

gepulsten und von der Leistungsflussdichte und von der Art der

einem konstanten angewendeten Modulation ab.

(kontinuierlichen) Die aufgedeckten Änderungen unter Pulsmodulation

elektromagnetische scheinen unabhängig von der thermischen Wirkung

n Feld untersucht. Diesein. Im Gegenteil dazu scheinen die eineder

zu Ergebnisse deuten darauf hin, dass Art

chronische wiederholte Exposition in Mikrowellen,

bei Leistungsflussdichten, die keinen

Temperaturanstieg hervorrufen, zum Auftreten

morphologischer Läsionen führen könnte, indikativ

für metabolische Störungen der Myelinscheiden und

der Glia-Zellen, was durch das Auftreten seltsamer ↓+ ↓++

Enzym-Aktivitäten;

metachromatischer kugeliger Körper in der weißen (Acetylcholinesterase- (Acetylcholinesterase-

morphologische/histopathologische CEF; morphological and attenuation (pw)

nn Substanz des Gehirns und des Kleinhirns zum activity) activity)

Veränderungen des ENA; pathological

ische/histopathologische Veränderungen (morphologische und histologische Bewertung des Gehirn-Gewebes (z.B. Läsionen, sphärische (kugelige) Körper, die metachromatisch anffärbbar sind, Ödeme; verschiedene Färbe-Methoden)); Effekte auf das neurologische System. Die Ergebnisse deuten darauf hin, dass eine chronische wiederholte Exposition in Mikrowellen, bei Leistungsflussdichten, die keinen Temperaturanstieg hervorrufen, zum Auftreten morphologischer Läsionen führen könnte, indikativ für metabolische Störungen der Myelinscheiden und der Glia-Zellen,

nn nn no EXP (in vivo -> -/- yes nn nn nn nn nn

Gehirngewebes; EOR; changes; Ausdruck kommt. Eine proliferative Reaktion der

vitro) Glia-Zellen wurde auch aufgedeckt. Biochemische ↓+ ↓++

Effekte auf das neurologische NES cell function attenuation (pw)

Bestimmungen und Bewertungen der (Bernsteinsäuredehyd (Bernsteinsäuredehydr

System

histochemischen Präparationen zeigen, dass die rogenase-activity) ogenase-activity)

Acetylcholinesterase-Aktivität und die

Bernsteinsäure-Dehydrogenase-Aktivität nach

chronischer Mikrowellen-Exposition abnimmt. Dieser

Effekt ist nach gepulster Mikrowellen-Exposition

ausgeprägter als nach Exposition bei

The authors kontinuierlichen Wellen (CW), was signal

69% showed some response to RFtiefere exposure, The authors concluded that

examined the 52% excitation and 17% inhibitory response. irradiation of nerve cells in the

responses of bird With an unmodulated 900 MHz signal: none of 3 avian brain with a RF signal typical

brain neurons to cells exhibited any response. of a GSM cell phone produced

exposure to Four cells that did not respond to the modulated changes in neural activity for more

cellular phone-type signal at its usual power than half of the measured cells

radiofrequency density (0.1 mW/cm2) were tested at higher power (69% in these experiments). Most ↑++ (52%; excitation, increase (pw)

neuronal

(RF) fields. Thirty- membrane function densities, up to 0.5 cells responded by increasing their incresing firing rate) ;

activity nn nn nn EXP SIG in situ -/- yes nn nn pre-exposure ↑(+); ↓(+) ´-

four zebra finches mW/cm2. Three of these cells showed no response rate of firing (by an average 3.5- ↓+ (17%; inhibitory

(firing rate of the neurons)

(Taenopygia at the higher power fold), while a minority of responding respone) decrease (pw)

guttata) were densities and one cell responded at 0.3 mW/cm2 cells exhibited decreases in

anesthetized with with a depression of its spontaneous firing. Whether similar

an im injection of firing rate. neuronal responses occur in other

0.05-mg/g mammals, including humans,

ketamine:0.01- warrants further study. The

mg/g xylazine and authors noted that a previous study

damage of eye lenses both by PW and CW at 5.5

GHz, recognized at the 4 th day of irradiation Preliminary results with 70

EOR; changes of the MW energy is more harmful at ↑+ (damage of eye ↑+ (damage of eye

histological damage of zwischen kontinuierlichen (CW) undyes gepulsten Mikrowellen-Befeldung gefunden werden. Eine Schädigung der Linse war nahezu immer am vierten Tag nach der Befeldung zu erkennen. Ein Vergleich der Ergebnisse, die bei unterschiedlichen Frequenzen erhalten wurden, weisen darauf hin, dass die Mikrowellen-Energie um so schädlicher wird, umso mehr die Frequenz zunimmt. Vorläufige Resultate der Befeldung bei 70 GHz lassen auf einen thermischen Effekt der Mikrowellen-Befeldung schließen

konnten keine Unterschiede eye lens einer nn nn einer EXP in vivo no -/- nn GHz irradiation suggest nn nn

EYE neurological system lower frequencies. lenses) lenses)

thermal effects of the MW.



Birenbaum et al. no difference between the effects on the parameters

(1975), in another at cw and pw

EKGs, CVS;

subcutaneo endeavor to

respiration rates, subcutaneous yes yes EXP RES; in vivo physiology no -/- nn nn nn nn nn ´- ´-

us replicate the results

temperatures TMP

of Presman and

Levitina,

concurrently

Temporary Frequencies that produced an increased amplitude ↕++ (increased ↕+ (increased

changes in of EEG alpha component, increased slow wave amplitude of EEG amplitude of EEG

electroencephalogr index, and desynchronizations included 200, 350, alpha component, alpha component,

ams (EEG) and 360, and 365 MHz CW radiation, and 9100 and Since the relaxation frequency increased slow wave increased slow wave

behavior were 9150 MHz pulsed radiation. Frequencies that of protein-bound water is index, and index, and amplification (cw)

observed produced decreased amplitude of EEG alpha considered to fall between 0,1- desynchronizations; desynchronizations;

in a pilot study changes of the component, increased slow wave index, and 1 GHz, absorptions and 200, 350, 360, and 9100 and 9150 MHz

EEG; BEH; in vivo

nn nn nn EXP involving the neurological -/- yes desynchronizations ranged from 130-960 MHz for nn nn quantum effects may be the nn nn 365 MHz CW pulsed

behavior CNS probands

exposure of five system; behaviour CW radiation and 9150 MHz for pulsed radiation. mecha-nistic basis for the radiation)

men and five Mental and behavioral changes were also noted and EEG changes. ↓++ (decreased

women (ages, included short term memory impairment followed by It is likely that resonance ↓++ (decreased amplitude of EEG

18-48 yr) to concentration inhibition and irritability, apprehension, absorptions occurred. amplitude of EEG alpha component,

radiofrequency and mental and physical sluggishness. alpha component, increased slow wave

(RF) and The EEG changes seen in most of the increased slow wave index, and

microwave participants were produced by CW RF radiation index, and desynchronizations;

Previous studies Exposure of BP-4 or unidentified neurons to a CW

Because bursting responses to PW

have revealed field at SARs from 0.5 to

irradiation were not due to ionic

differences in the 4.0 W/kg did not change firing rate patterns

current activation by mediators or

response of noticeably. However, PWs

to thermal effects in their system,

molluscan within the same range of SARs caused changes

the authors propose that the

neurons to CW in firing rate and provoked burst-like changes

observed biological effects

and to PW independent of modulation frequency between

electromagnetic might have been caused by

spontaneous electrical 0.5 and 100 pps, but sensitive to SAR at a change (pw)

fields (EMFs). mechanical vibrations in the ´- (firing rate) ↕+ (firing rate)

activity and ionic currents of neurons external threshold near 0.5 W/kg. Bursts occurred at the

yes yes EXP SIG in vitro These investigators membrane function -/- yes nn chamber resulting from nn nn nn nn (interburst interval) ↓+ (interburst interval)

(firing rate, medium very beginning of exposure with a latency of 42 sec

explored the exposure to the pulse- ´- (ionic currents) ´- (ionic currents)

bursting patterns) (+/- 22 sec), and did not reappear over the 10-min

effects of CW and modulated field. There is also no

exposure period. PW exposure (SAR of 2 W/kg,

PW EMFs on the indication of a "window" effect at a

16 pps) also decreased the interburst interval in

bursting patterns specific combination of frequency

neurons with irregular spiking activity from a mean of

(BPs) and and intensity, since the bursting

290 +/- 70 sec (n=50) to 140 +/- 21 sec (n=15). In

receptor systems response to PW exposure was not

these experiments, bursts were not evoked by

of neurons of frequency-dependent over the

conventional heating rates up to 0.2 C/sec, and in

Lymnea stagnalis. range examined.

fact, showed a decrease in firing rate and cessation

Reportedly, the

The authors have The differences between exposed and sham- To explain the frequency

shown earlier irradiated groups appeared significant (at p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









embryo

EFFECTS OF 460 MHz MW 6; (Drosophila melano-

Bol'shakov, M. A.; Radiats Biol

Bol'shakov, M. Tomsk State RADIATION AND ELEVATED 10; above (cw) gaster, cell

19 Tomsk I. R.; Russia physiol@bio.tsu.ru

Kniazeva,State Univ., 36 Lenin Ave., Tomsk 634050, Russia, e-mail: 2002 Radioecol 0.46 0.46 none 6 nn nn pulsed nn nn 6 0,12 / 3 cw > pw nn nn nn 5 minutes acute continuous 0 nn 15,000 cell

A. Univ. TEMPERATURE ON 16; below (pw) Cantor S.,at (embryo)

Evdokimov, E. V. 42(2)

DROSOPHILA EMBRYOS 22 sensitive age: 15 hr,

10 min))









Ogden 0,36;

0,18;

BioServices 10; 7,2 - 160 0,73; Varian

Brown, D. O.; CHARACTERISTICS OF MW Bioelectro- 0,36; nervous

Corp.; 25.000; (CW); 1,45; traveling Cober mouse

g, MD (D.O.B., S-T.L.); Dept. of Microwave Res., Walter ReedArmy Inst. of Res., Washington, DC1994

20 Brown, D. O. Lu, S-T.; USA (E.C.E.); 6 Montgomery Village Ave., Suitemagnetics

222, Gaithersburg, MD20879 (RR/S-T.L.)

EVOKED BODY 1.25 1.25 none 80 80 10 pulsed nn 0,73; nn above nn nn nn nn nn 0 female nn whole body (MW induced body

Walter Reed 2000 160 or 16 0,90; wave tube transmitter (BALB/c)

Elson, E. C.hu MOVEMENTS IN MICE. 15(2) 1.45 movements)

Army Inst. of ms for PW 1,03; amplifier

kJ/kg

Res. 1,05









DIFFERING EFFECTS OF

PULSED AND CW MW IEEE Trans

Walter Reed 5 / 5.000

Brown, P. V. Brown, P. V. K.; ENERGY UPON NERVE Microw clearly nerves cell: cell

21 Army Walter Reed Army Inst. Research, Washington, DC 20012

Dept. Microwave Research,Inst. USA 1980 nn nn nn 1000 1000 1 1 pulsed (PW) nn 123 cw = pw nn nn nn nn nn nn 0 nn nn

K. Larsen, L. E. FUNCTION AS DETECTED Theory Tech above (crab) nerve (nervous)

Research 5 (CW)

BY BIREFRINGENCE 28(10)

MEASUREMENTS









MW RADIATION, IN THE

ABSENCE OF Cober high power microwave

pulsed; 30 minutes;

Browning, M. Browning, M. D.; The Rockefeller HYPERTHERMIA, HAS NO Neurotoxicol 2 500 (2,8 6000 1; 5; 10; 20; 1; 5; 10; 20; generating system or acute; continuous; histological cut

22 USA

Lab. of Molecular and Cellular Neuroscience, The Rockefeller Univ., 1230 York Ave., New York, NY10021

1988 0.5 2.8 10000 10000 modulated at 16 nn 1; 2 (chronic exp) cw = pw above nn far-field 23 h/daysfor 0 rat nn nn whole body

D. Haycock, J. W. Univ. DETECTABLE EFFECT ON Teratol 10(5) 2,45 GHz) (2GHz) 50 50 Microwave Cavity Laboratory chronic intermittent (nervous)

Hz Model 15022 generator 7 days

SYNAPSIN I LEVELS OR

PHOSPHORYLATION.









0,5-32

(0.3 Hz tapered, open coaxial antenna

Caddemi, A.; organ

MW EFFECTS ON Bioelectro- higher or connected to a

Tamburello, C. C.; Universita di (heart of chick, part: organ

23 Scienze, 90128 Palermo,Italy (RR/C.C.T.)

Dipartimento di Ingegneria Elettrica, Universita di Palermo, Viale delleItaly

Caddemi, A. 1986 ISOLATED CHICK EMBRYO magnetics 2.45 2.45 none 0.5 lower nn nn pulsed nn 3 0.95 cw = pw close to nn Hewlett Packard up to 3 hours acute continuous 0 nn 39

Zanforlin, L.; Palermo 9 - 12 day old heart (cardio-vascular)

HEARTS 7(4) than the model 8620B microwave

Torregrossa, M. V. embryos)

natural generator

rhythm)









Universita di

Bologna;

Calzoni, G. L.;

Ass. per la WEAK EXTREMELY HF MW cell; (directly

Borghini, F.; CromoStim 2000 unit

Medicina AFFECT POLLEN-TUBE irradiated)

Del Giudice, E.;

Applicata EMERGENCE AND J Altern (PromoPharma, pollen water, used for

Betti, L.; nn nn cw = pw medical Republic of San Marino; cell

M.M.); Associazione per la Medicina Applicataalla Ricerca Italiana sull'Aqua, Roma, ItalyComplement Nazionale di78

peranza@mail.cib.unibo.it (RR/A.S., G.L.C. F.D.R., alla Ricerca

24 Calzoni, G. L. Italy 2003 GROWTH IN KIWIFRUIT: (F.B.); Istituto 40 Fisica 40 - 78 Milano,Italy (E.D.G.); Dipartim nn

Nucleare, 10 10 nn pulsed 0.02 nn nn 30 minutes acute continuous 0 (kiwifruit Actinidia nn nn growth

Dal Rio, F.; (0,02 W) application (reproductive)

Italiana POLLEN GRAIN Med 9(2) device designed for magnetic deliciosa) medium

Migliori, M.; resonance therapy)

sull'Aqua; IRRADIATION AND WATER- (indirectly

Trebbi, G.;

Istituto MEDIATED EFFECTS irradiation)

Speranza, A.

Nazionale di

Fisica Nucleare









Capri, M.;

Scarcella, E.;

Univ. of

Fumelli, C.; IN VITRO EXPOSURE OF

Bologna; TEM cell

Bianchi, E.; HUMAN LYMPHOCYTES TO cell

Telecom Italia (model IFI CC104SEXX) 1 hour/day

Salvioli, S.; 900 MHz CW AND GSM (lymphocytes,

Mobile; fed by a for 3 days;

Mesirca, P.; MODULATED RF: STUDIES Radiat Res peripheral blood 31 volunteers cell: cell culture

Univ. of F.B.); Mobile, Torino, Italy (A.A., A.S.); ICEmB,Centro Interuniversitario Interazione Campi Elettromagnetici e Biosistemi, Univ. nn Genoa, Genova,Italy (F.B.); Dept. Gerontological Res., INRCA, Anacona, Italy (C.Franceschi); CentroInterdipartimentale "L. Galvani," Bologna, Italy (M.C., G.C., F.B., C.Franceschi)

Physics, Univ. of Bologna, Bologna,Italy (P.M., C.A., G.C.,Genoa;TILab, Telecom ItaliaItaly

25 Capri, M. 2004 0.9 0.9 none 217 217 of nn GSM-like nn nn 0,07/ 0,076 / cw = pw below nn nn 30 minutes- acute intermittent 1 nn

Agostini, C.; OF PROLIFERATION, 162(2) PC-controlled mononuclear cells, nn cells lymphocyte (immune)

INRCA; power amplifier and/or a intervalls/day

Antolini, A.; APOPTOSIS AND of human healthy

Centro commercial GSM cell phone

Schiavoni, A.; MITOCHONDRIAL young volunteers)

Interdipartimenta

Castellani, G.; MEMBRANE POTENTIAL.

le "L. Galvani,"

Bersani, F.;

Franceschi, C.





Forschungsgemeinschaft Funk e.V. 2f7970c4-fa63-48a5-bb8d-bba54b3501af.xlsstudies

Seite 7 von 100

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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



In a previous study Exposures to continuous wave EMR at 24.5 or 40 C

(Bol'shakov et al., resulted in approximately the same dPID values:

Radiats Biol 3.2 +/- 0.7 or 3.8 +/- 1.1%, respectively. Effects of

Radioecol 41:399- exposures with pulse modulation depended on

402, modulation frequency, and were different at

2001; BENER normal incubation temperature and under ↑++ (PID value, 6 and

Abstract No. The authors assume that

number of nonflown imagoes per heating. At frequencies of 6 and 22 Hz, dPID 22 Hz, 24,5 und 40°C)

exposure to pulse EMR at increase (pw)

hundred 23743), the values in exposures without heating were ↑+ (PID value, 10 and

modulation frequencies of 10 sham ↑(+) vs.

ovipositions external authors showed approximately 7%. With heating, the EMR effect sham-exposure and ↑+ (PID value, 24.5 16 Hz, 24,5°C)

yes yes EXP TER in vitro teratogenity -/- yes nn nn and 16 Hz initiates a non- control ´- (PID

= medium that the effect of was insignificantly (by 1-2%) higher. At frequencies shelf control und 40°C) ↓+ (PID value, 10 and

pulse-modulated thermal mechanism values)

percentage of interrupted of 10 and 16 Hz, exposures at 24 C resulted in dPID 16 Hz, 40°C)

electromagnetic that normalizes embryonic contrary effects

development (PID) values approximating 4%, whereas at 40 C, the

radiation (EMR) on development

effect was significantly lower (approximately 1%,

Drosophila embryos with p equal or less than 0.05).

depended on the

modulation

frequency.

Extending that

investigation, the

The characteristics The incidence of MW evoked body movement The authors concluded that

of microwave inceresed with dose. The dose response curves microwave evoked body

induced body appeared to level off at doses higher than 16 J for movements can be considered to

movements in either type of microwave mode. Significant be a special example of a

mice were differences in incidence rate were noted for biological response to a high

investigated. different peak or average power. A 20-W/20-J rate of energy deposition as

Female BALB/c microwave was therefore considered to be the reflected by the high threshold for

rectal or mice were placed requisite for evoking body movements at the sc heating rate

body movements; body and cranial along the in a motion maximum rate in mice. Higher doses or higher (0.24 C/sec). Due to the high sc ↑+(body movement) ↑+(body movement)

yes yes EXP BEH in vivo motor system no -/- nn nn yes nn

sc temperatures middle of resistant test power microwaves did not evoke additional heating rates, the microwaves ↑+ (sc temperature) ↑+ (sc temperature)

the cranium chamber that was responses. The mice also showed evoked body used in these experiments must

placed in a low-Q movements to the acoustic and tactile stimuli. The be perceived by the mouse as

[quality factor] durations of the responses induced by the an intense thermal sensation but

resonant cavity. microwave radiations and the acoustic and tactile not a pain sensation because the

They stimuli did not differ significantly. The maximum temperature increment was

had been increases in body temperature induced by the well below the threshold for

instrumented with microwave exposures were changes of the calcium-dependent absence of hyperthermia, may not `- (synapsin I

yes nn EXP SIG quantitative no -/- no significant effect on nn sham-exposure ↓+(hyperthermic ↓+(hyperthermic

and levels of synapsin I prodiced vitro neurological system synapsin I significantly alter these levels);

indicator of synapsin I levels. reduction of synapsin reduction of synapsin

moderate (1- phosphorylation, but components of synaptic transmitter

neurotoxicity. In levels) levels)

3C) the effect was not release and neuronal function.

order to investigate

hyperthermia statistically significant.

possible neurotoxic

effects of

microwave (MW)

radiation, calcium-

dependent

Based on previous

reports of A preliminary experiment investigating the effects of The authors concluded that

microwave- increasing the temperature on heart rate found that microwave irradiation of isolated

induced the beat rates increased linearly with temperature chick embryo hearts alters cardiac

bradycardia over the 35-40 C range by 0.1 to 0.25 Hz/C. activity. CW irradiation caused a

(decrease in slight bradycardia, while pulsed-

beating rate) in Of the remaining 36, 26 started to pulse normally modulated fields (in the change (pw;

cardiac tissue from within 10 min. The other 13 showed a persistent The locking of the heart rate to

physiological frequency range) depending on

turtles and frogs, strong arrhythmia. In experiments with pulse- the modulation frequency ↕+ (heart rate; ↕

external locked the cardiac frequency to the modulation frequency)

heart beat rates yes yes EXP CVS in vitro the authors organ function -/- yes modulated microwaves, modulation frequencies that nn could reflect a rectification of ´- ↓+ (heart rate) depending on

medium modulation frequency, increased nn (pre-exposure)

examined the were at least 0.3 Hz higher or lower than the natural the MW signal at membrane modulation frequency)

heart rate amplitude, and could

effects of level.

rhythm were used. In 85 of 108 tests, locking of regularize heart rates in cases

microwave the cardiac frequency to the modulation where strong arrhythmias or

radiation on frequency was observed. The synchronization extremely weak activity were

isolated chick was typically delayed by up to 10 min, although in evident. It is not easy to identify a

embryo some cases it was immediate. In the remaining 23 mechanism for the observed

hearts. Fifty one tests, no significant effects were detected. effects.

living hearts In 6 tests, irradiation was performed with an initial

obtained from 9- to

The authors modulation frequency close thethe rate of an pollen

Results were expressed as to percentage of ´- (tube emergence

examined the grains producing a tube. A germination test on ´- (tube emergence and growth, directly

effects of weak basal medium using untreated pollen indicated and growth, directly after direct irradiation)

The authors concluded that either

extremely high germination was 80.0 +/0 3.0%. after direct irradiation)

frequency (EHF) direct or indirect irradiation with ↑+ (tube emergence

The initial level of pollen tube emergence and

EHF microwaves produced by the

microwave growth in directly irradiated pollen grains did ↑(+) (tube and elongation, 2-4

radiation on pollen CromoStim 2000 appear to days after direct

not differ significantly from control values when emergence and

significantly affect pollen growth

growth processes measured just after irradiation with pulsed elongation, 2-4 days irradiation)

in kiwifruit. This processes. In both cases, water

GRO; cell vitality, cell microwaves. The extent of tube growth however after direct irradiation)

tube emergence; tube elongation nn nn nn EXP in vitro -/- yes nn appears to play a primary role, and nn control ´-

REP system was used division appeared to be significantly reduced at this time ↑++ (growth tube

the authors interpreted these

as an objective, (p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=



INHIBITION OF DNA

SYNTHESIS AND

ENHANCEMENT OF THE

Chang, B. K.; cell

Duke Univ. UPTAKE AND ACTION OF Cancer Res 10 / 111 - cw ≤ pw medical cell: cell

26 Chang, B. K. USA

Div. Hematology & Oncology, Dept. Medicine, Duke Univ. Medical Center, Durham, NC 27710

Huang, A. T.; 1980 1 1 none nn nn nn nn pulsed nn 5 - 50 nn nn AIL 125 generator nn 20 minutes acute continuous 0 (L1210 leukemia nn nn

Medical Center METHOTREXATE BY LOW 40(4) 121 cw ≥ pw application L1210 leukemia (haematopoetic)

laJoines, W. T. cells)

POWER-DENSITY MW

RADIATION IN L1210

LEUKEMIA CELLS









EFFECTS OF MW

Microwave

EXPOSURE AT VARIOUS 0,1;

Chiang, H.; Instit., Zhejiang

POWER DENSITIES ON J Bioelectr 2,45 1,0; 0,5; mouse histological cut

27 Chiang, H. Microwave Instit., Zhejiang Medical Univ., Hangzhou, 310006 China

Yao, G. D.; Medical Univ., China 1984 3 (pw) none 935 935 1.2 1.2 pulsed nn nn cw ≥ pw above nn nn 3 hours acute continuous 0 nn > 10 whole body

MITOCHONDRIAL MARKER 3(3) (cw) 5,0 1,0; (C57BL, adult) (nervous)

Zhou, S. Hangzhou,

ENZYMES IN MOUSE 5,0

310006 China

BRAINS









nerves,

IEEE Trans below / muscles

Univ. EFFECTS OF EMF ON / part: organ

Chou, C-K.; Microw nn close to / S-band waveguide (frog;

28 USA

Bioelectromagnetics Res. Lab., Dept. Rehabilitation Medicine RJ-30, Univ. Washington Sch.Medicine, Seattle, WA 98195

Chou, C-K. Washington 1978 ISOLATED NERVE AND 2.45 2.45 none nn nn nn nn pulsed nn 0,3-1.500 300 - nn nn near-field nn nn nn 0 nn nn nerve; (nervous; muscle-

Guy, A. W. Theory Tech clearly cat;

Sch. Medicine MUSCLE PREPARATIONS. 220.000 muscle sceleton)

26(3) above rabbit;

rat)









Chou, C.K.;

A.W. Guy; Effects of continuous and Radio / 1,64 head, 2 hours/day

29 Chou, C-K. nn nn USA 1979 2.45 2.45 none nn nn 10 10 pulsed nn 1.5 cw = pw below nn nn temporary intermittent 0 nn nn nn nn nn

J.A. McDougall; pulsed MW exposure on rabbits Science. 14 2,1 body for 3 months

L.-F. Han









pulsed; pulsed

Chou, C-K.; Univ. MW RADIATION AND 20 rabbit whole body

J Microw 1; (syncron with R cw = pw; cw > close to /

30 USA HEART-BEAT WA 98195

Bioelectromagnetics Research Lab., Dept. Rehabilitation Medicine RJ-30, Univ. Washington Sch.Medicine, Seattle,RATE OF

Chou, C-K. Han, L. F.; Washington 1980 2.45 2.45 none 700 700 1 nn 5; 80 5 / 7,1; 13,7 0,12 - 1,79 nn nn nn minutes/day temporary intermittent 0 (New Zealand nn 3 (dorsal; cardio-vascular

Power 15(2) 10 wave of the pw above

Guy, A. W.sea Sch. Medicine RABBITS for 10 days albino, adult) ventral)

cardiogram)









Chou, C-K.; 2 hours/day,

Univ. EFFECTS OF CONTINUOUS pulse generator rabbit

Guy, A. W.; 5 9 male; 9

31 USA

Bioelectromagnetics Res. Lab., Dept. Rehabilitation Medicine, Univ. Washington Sch. Medicine,Seattle, WA 98195 MW

Chou, C-K. Washington 1982 AND PULSED CHRONIC Radio Sci 17 2.45 2.45 none 100 100 10 10 pulsed 10 1.5 1,5 / nn 1,6 - 2,1 cw = pw above nn far-field temporary intermittent 0 (New Zealand, 3 18 whole body whole organism

McDougall, J. A.; (Applied MW Lab. PH4OK) days/weeks female

Sch. Medicine EXPOSURE ON RABBITS mo old)

Han, L-F. for 90 days









EFFECTS OF PULSED MW J Microw

Yee, K-C.; Univ. 8.55; below (cw)

RADIATION ON THE Power S-band, WR-284 continuous; organ part: organ

Bioelectromagnetics Research Lab., C-K.; Center for Bioengineering, Univ. of Washington Schoolof Medicine, Seattle, WA 98195 (RR/A.W.G.)

32 Chou, C-K. Chou, RJ-30, Washington USA 1986 2.45 2.45 none 16 16 10 10 pulsed nn nn 0.003 2; cw or pulsed wave synthesis was a function of power density, with a ↑+ (MTX uptake, ↑+ (MTX uptake, DNA

action of 3H-MTX (methotrexate); nn nn nn EXP cell vitality, cell no -/- nn be improved by nn nn nn

TUM vitro; in vitro (PW) microwave peak effect between 15- 25 mW/cm2 for CW DNA synth inhibition) synth inhibition)

DNA synthesis division the use of MW

(MW) radiation on radiation, perhaps attributable to increased

the cellular uptake membrane permeability in MW-exposed cells. PW

and exposure at 10 mW/cm2 gave a similar inhibition. In

action of vivo, combined treatment with 5 mW/cm2 MW

methotrexate radiation for 20 min and MTX altered the duration of

The effect of Mice exposed to PW microwaves at incident power

continuous wave densities of 0.5 mW/cm2 or more had significantly

(CW) or pulsed decreased amounts of SDH and MAO in both the

wave (PW) hypothalamus and hippocampus. The lowest

microwave levels occurred in the 5 mW/cm2 group. Additional

exposure on groups of mice were exposed at 0, 0.3, and 0.5

brain mitochondrial mW/cm2 to PW microwaves to establish a The authors conclude that PW

brain mitochondrial enzymes: enzymes succinate threshold. Significantly reduced SDH activity was microwaves are more effective

↓+ (at 5 mW/cm2; ↓+ (at 0.5, 1.0, 5.0 attentuation

succinat dehydrogenase (SDH) and in vivo -> dehydrogenase observed only in the 0.5 mW/cm2 group. Mice than CW microwaves in

monoamine oxidase (MAO)

nn nn nn EXP ENA

vitro (SDH) and cell function -/- yes

exposed to CW microwaves showed a significant

nn

decreasing brain SDH

nn sham-exposure nn SDH- und MAO mW/cm2; SDH- und (pw;dependening on

monoamine levels) MAO levels) PFD)

(by microspectrophotometry) reduction in enzyme activity only at 5.0 mW/cm2. and MAO levels under the

oxidase (MAO) in experimental conditions used.

mice was studied

using

histochemical

methods. Groups

of

10 adult C57BL

mice in were sciatic

Isolated frog sham- As long as the temperature of the nerves or muscles

nerves, cat was kept constant, no changes in amplitude or

saphenous nerves conduction characteristics or

rabbit vagus in contraction were observed for CW and PW. ´- (stimulation of

nerves, Changes No direct electric field stimulation ´- (stimulation of

2) muscles and axons);

NES; of nerve axons, ganglia, or muscles muscles and axons);

nerve action potential; muscle 1) fix 2) measured superior cervical observed at the highest power levels were due to ↑+

yes EXP MUS; in vitro ganglia, and rat membrane function no -/- associated increases in nn was nn nn nn ↑+

contractile tension yes in ext (thermal stimulation

SIG diaphragm temperature and were duplicated by increasing the observed during microwave (thermal stimulation of

solution of muscles and

muscles solution temperature. irradiation. muscles and axons)

axons)

(maintained at a

constant

temperature by

Ringer's solution) Keine Effekte bei: Körpergewicht, EEG,

Körpergewicht, EEG, nn morphoplogical and

hämatologische Tests, Catarakt-Bildung im Auge

2450MHz, 1,5mW/cm², 2h/d, 3 Monate. Eine Gruppe CW, eine Gruppe 10µs Pulse. Peak vivo ->

hämatologische Tests, Catarakt- nn nn nn EXP EOR (in SAR Kopf: 1,64 W/kg, Körper 2,1W/kg. Keine Effekte bei: Körpergewicht, EEG, hämatologische Tests, Catarakt-Bildung im Auge

pathological no -/- nn nn nn nn nn ´- ´-

Bildung im Auge vitro) changes

The effects of The relative change in heart beat was random in

microwave (MW) nature for ventral and dorsal exposures to both

radiation on heart CW and PW MW energy. With dorsal high-power

rates were studied. CW exposure , the animals were disturbed by heat

Three stress; after exposure, heart rates increased, then

adult New Zealand returned to normal after about 20 min. Exposure to

albino rabbits were PW, synchronized to the R wave peak of the EKG

exposed both lead to random changes in heart rate; Only one

dorsally and rabbit showed a consistent positive chronotropic

heart beats (EKG), SAR nn nn nn EXP CVS in vivo ventrally physiology no -/- nn nn nn nn nn ↕+ (hearbeat) ↕+ (hearbeat)

effect, when the pulse was delayed 100 or 200

to 2450-MHz MW msec. No cumulative effects were observed over a

plane waves for 20 period of 4 mo.

min/day for 10

days under each of

several

field conditions:

continuous waves

(CW) at 5

mW/cm2; pulsed

The effects of No significant differences were observed

exposure to between the exposed and sham rabbits in body

continuous wave wt (measured every other day); EEG and evoked

(CW) and pulsed potentials (recorded 1/wk); blood tests

microwave (MW) (hematological, chemical, and morphological studies,

fields for a 3-mo 1/mo); or cataract examination before and after

period were the 3-mo exposure. However, 5 animals injected

investigated and ´- ( EEG; ´- ( EEG; ´- ( EEG;

EEG; growth; with apomorphine died (1 exposed to CW, 3 pulse-

compared in 18 evoked potentials; evoked potentials; evoked potentials;

evoked potentials; blood; morphological and exposed, and 1 sham exposed) , indicating

nn nn nn EXP EOR in vivo New Zealand no -/- nn nn nn sham-exposure blood; blood; blood;

cataract; pathological sensitivity to it. The remaining 5 rabbits showed no

rabbits (3 mo old; 9 cataract; cataract; cataract;

tissue damage changes histopathological changes.

male, 9 female). tissue damage) tissue damage) tissue damage)

Animals were

placed in Plexiglas

cages and

exposed singly in

miniature anechoic

chambers to CW,

pulsed, or

Contradictory The contractile rates of hearts in the control group

effects of dropped linearly during the 60-min recording period

microwave to about 67% of its initial beat rate. All of the groups

exposure on heart showed no significant alteration in the reduction of

rate have been heart rate with time compared to

reported the control that could be directly attributable to The authors concluded that the

in the literature. microwave exposure. effects of pulsed microwave 1) ´- (nonthermal

Several Significant differences were seen between the 1) ´- (nonthermal

heart radiation on the isolated frog hearts reduction of heart

investigators have controls and the groups where a tempearture reduction of heart

muscle; are purely thermal and no rate);

contractile rates yes yes EXP CVS in vitro organ function no -/- nn nn sham-exposure ´- rate);

external reported effects incease in the ext solution, either due to MWs or bradycardia, as was previously 2) ↑++ (thermal

ranging conventional heating . 2) ↑++ (thermal

solution reported, occurs when hearts are reduction of heart

from bradycardia reduction of heart rate)

isothermally exposed to microwave rate)

to tachycardia, radiation.

including no effects

at all. Soviet

investigators

reported severe

clinical symptoms

including

The effects of Statistically significant and consistent changes were

relatively low noted in glucose, BUN, and uric acid following ↑++ (glucose, BUN,

power density microwave exposure. The response appeared to uric acid; 25

2

microwave be dose-dependent with increases of 44% in mW/cm )

exposures on animals exposed at 25 mW/cm2, continuous

gross and histopathological various wave (CW); 29% in animals exposed to 10 ↑+ (glucose, BUN,

examinations serum components mW/cm2, CW; and 18% in animals exposed at 5 It is concluded that the results of uric acid; 5 and 10

were studied in 6- 2 ?

morphological and mW/cm2, CW. Other serum components did not the blood chemistry and sleeping mW/cm )

serum components (i.e. calcium, HCS; in vivo -> to 10-mo-old Dutch pathological show consistent variation from baseline values. time experiments were consistent nn

yes rectal yes EXP rabbits weighing -/- yes nn nn nn nn increase (cw)

inorganic phosphate, glucose, uric BEH vitro changes; Observed physiologic response, as well as rectal with a dose-dependent response to ´- (other serum ´- ?

2.09 +/- 0.29 kg. changes (cw)

acid etc.) physiology temperature measurements, indicated that the a nonspecific thermal stress at all components)

Both continuous decrease (cw)

thermoregulatory capability of the rabbits was power densities used.

sleeping time wave and pulsed sufficient to compensate for the thermal burden at 5 ↕+ (nephrosis; 25

mode 2-hr and 10 mW/cm2 but could be overridden by a 2-hr mW/cm2)

exposures at exposure at 55 mW/cm2. Pathology findings

2.45 GHz were included a mild, repairable nephrosis in animals ↓+ (sleeping time; 5-

used at power exposed at a power density of 25 mW/cm2. A 2

50 mW/cm )

densities of 25, 10, further investigation of analeptic effects in

and 5 mW/cm2. phenobarbital sedated rabbits at power densities







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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn nn









nn nn









nn thermal









nn nn









yes nn









nn nn









nn thermal









athermal (5

and 10

2

nn mW/cm )

thermal (55 (25

2

?) mW/cm )









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=





INVESTIGATION OF THE

cell:

EFFECTS OF CW, PULSE-

Liu, L-M.; Bioelectro- pulsed and cell single cells of

AND cell

34 Cleary, S. F. Garber, F.; nn nn USA 1982 magnetics 2.45 3 2.7 nn nn nn nn sinusoidally- nn nn nn nn nn nn waveguide exposure chamber nn nn nn nn 0 (green alga nn 65 Chara corallina;

AM MW ON SINGLE (algae Chara corallina)

Cleary, S. F. 3(2) modulated Chara corallina) green algae

EXCITABLE CELLS OF

giant cells

CHARA CORALLINA









cell:

RBC

(whole -

Cleary, S. F.; Virginia EFFECTS OF X-BAND MW Bioelectro- 138; waveguide exposure cell

heparinized- cell

35 Cleary, S. F. USA

Dept. Biophys., Med. Coll. Virginia, Virginia Commonwealth Univ., Richmond, VA 23298

Garber, F.; Commonwealth 1982 EXPOSURE ON RABBIT magnetics 8.42 8.42 none 138 413; 5 5 pulsed nn nn / 14500 21.7 21.6 cw = pw above nn chambers nn 2 hours acute continuous 0 (rabbit, nn nn

blood sus- (haematopoetic)

Liu, L. M. Univ. ERYTHROCYTES 3(4) 555 adult Dutch)

pensions

or washed

cells)









described by Cleary et al.

(Bioelectromagnetics 6:53-60,

Cleary, S. F.; 1985; BENER Abstract No.

EFFECT OF ISOTHERMAL cell cell culture:

Du, Z.; Virginia 5 - 50;

RF RADIATION ON FASEB J cw ≥ pw; 2418) (T-lymphocytes of cytotoxic cell culture

Bioelectromagnetics Lab., Dept. ofG.;

36 Cleary, S. F. and Biophysics,

Cao, PhysiologyCommonwealth Medical Coll. of Virginia, VirginiaCommonwealth Univ., Richmond, VA 23298

USA 1996 2.45 2.45 none 50 50 6670 6670 pulsed nn nn 5 5 above nn near-field 2 hours acute continuous 0 nn nn

CYTOLYTIC T 10(8) cw = pw and Liu and Cleary cloned murine T-lympho-cytes (immune)

Liu, L-M.; Univ.

LYMPHOCYTES (Bioelectromagnetics 9:249- cytolytic) (CTLL-2)

McCrady, C.

257, 1988; BENER Abstract

No. 4753)









microscope stage exposure cell:

EFFECTS OF MOBILE

Cranfield, C. G.; system described by cell Jurkat

PHONE TYPE SIGNALS ON Anderson et al. (Development

Cranfield, C. Wood, A. W.; Swinburne Univ. Int J Radiat (human E6-1, cell culture

Australia andrewwood@swin.edu.au (RR/A.W.W., C.G.C., K.G.M., V.A.) 0.915

cal Sciences & Electrical Engineering, Swinburne Univ. of Technology, Melbourne,Australia, e-mail:2001

37 CALCIUM LEVELS WITHIN 0.915 none 217 217 nn nn GSM-like nn nn 1 - 2,1 cw = pw close to nn near-field 10 minutes acute continuous 1 nn nn

G. Anderson, V.; of Technology Biol 77(12) of a new in vitro RF exposure lymphocytes; American Type (immune)

HUMAN LEUKAEMIC T- device for confocal

Menezes, K. G. Yurkat cells) Culture

CELLS (JURKAT CELLS)

microscopy imaging) Collection









Stewart-DeHaan, P.

J.;

LENS CATARACT Invest

Trevithick, J. R.;

Creighton, M. Univ. Western FORMATION IN VITRO: Ophthalmol pulsed cw = pw (same lens part: histological cut

38 Creighton, M. O.; Canada

Univ. Western Ontario, London, Ontario, Canada1980 0.915 0.915 none nn nn nn nn nn nn nn nn nn nn nn 20 minutes acute continuous 0 nn nn

O. Ontario THE EFFECTS OF HEAT Vis Sci (high power) average power) (rat) lens (sensoric)

Ross, W. M.;

AND MW IRRADIATION 19(Suppl.)

Larsen, L. E.;

Jacobi, J. H.









Creighton, M. O.;

Larsen, L. E.;

Stewart-DeHaan, P. Univ. of IN VITRO STUDIES OF MW-

J.; Western INDUCED CATARACT.

lens

Creighton, M. Jacobi, J. H.; Ontario; Exp Eye Res 0.5 - 65 / cw = pw (same clearly part: histological cut

Ontario, London,Ontario (RR/ J.R.T., M.O.C.); Baskerville Associates, 319 Piccadilly St, London, Ontario, N6A 5C1,Canada; Dept. of Microwave Res., 0.918 Reed Armynone of Res., Washington, DC (L.E.L., J.H.J.)

estern39 Canada 1987 Walter 0.918 Inst. nn varied 10 10 pulsed nn 5,75 - 750 nn WR975 waveguide nn 6 minutes acute continuous 0 (rat, nn nn

O. Sanwal, M.; Walter Reed II. COMPARISON OF 45(3) 24000 average power) above lens (sensoric)

Sprague-Dawley )

Baskerville, J. C.; Army Inst. of DAMAGE OBSERVED FOR

Bassen, H. E.; Res. CW AND PULSED MW

Brown, D. O.;

Trevithick, J. R.









MW EFFECTS ON THE

Natl. Res. Inst. BLOOD-FORMING SYSTEM 2 hours/day

Ann N Y

40 Czerski, P. Dept. P. Genetics, Natl. Poland

Czerski, of Human of Mother and Res. Inst. of Mother and Child, Warsaw, Poland

1975 WITH PARTICULAR 2.95 2.95 none 1200 1200 1 1 pulsed nn 3 3 nn cw = pw above nn nn nn for 37 or 79 temporary intermittent 0 rabbit; nn nn nn haematopoetic

Acad Sci 247

Child REFERENCE TO THE days

LYMPHOCYTE.









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



Cells maintained at constant temp during exposure

showed no consistent or statistically significant

MW-dependent alterations in any of the dependent ´- (resting potential, ´- (resting potential,

electrophysiology cell reactions variables. The effects of intensity or pulse amplitude of the amplitude of the

(resting potent., conduction velocity, repetition rate windows, variations action potential, rise action potential, rise

BMP;

waveguide (i.e., under no impressed MW). The dependent variables measured before, during and after exposurein vitro S-band MW fields included: resting potential, amplitude of the action potential, rise and decay time of the action potential, conductionnn

amplitude of action potent., action fix nn nn EXP to the membrane function no -/- in modulation maintained at 22

velocity, and excitability. Cells index, exposure +/- 0.1 C during exposure showed no consistent or statistically significant MW-dependent alterations inand decay time of the variables. The effects of intensity or pulse repetition rate windows, variations in modulation index, exposure temperature, and carrier wave frequency w

nn nn nn and decay time of any of the dependent

CEF

potent. rise time, decay time of temperature, and carrier wave the action potential, action potential,

action potent., excitability) frequency will require further study. conduction velocity, conduction velocity,

and excitability) and excitability)





The effects of Statistically significant increases in K+ efflux

continuous wave compared to water-bath-heated controls were

(CW) and pulsed detected when RBC were exposed in whole blood

microwave (MW) suspensions to either CW or pulse-modulated

heating on the 8.42-GHz MW energy at specific absorption rates Measured differences in

permeability of (SAR) resulting in sample temperatures of 24.6 and sample heating rates and

erythrocyte (RBC) 24.4 C, respectively. Pulsed MW exposure resulted temperature gradients

plasma ↑++ (K+ efflux, whole ↑(+) (K+ efflux, whole

in a small but consistent enhancement of K+ efflux between MW-exposed and amplification (cw)

permeability of erythrocyte plasma membranes were blood suspension) blood suspension)

BMP; in 1:1 red cell suspensions and to a lesser heated control suspensions control (water bath

membranes: yes suspension yes EXP in vitro studied. RBC from membrane function -/- yes nn nn ´-

HCS extent in whole blood, compared with CW may account in part for the heated)

K+ efflux adult Dutch rabbits ´- (K+ efflux, 1:1 red ↑+ (K+ efflux, 1:1 red

exposure. No statistically significant K+ efflux differential effect of MW increase (pw)

were exposed as cell suspension) cell suspension)

occurred in the case of 1:1 red cell suspensions exposure, but such effects do

whole under the same exposure conditions. not appear to fully

(heparinized) blood explain the results of this study.

suspensions

or as washed cells

in 1:1 isotonic

buffered K+-free

saline suspensions

Previous in vitro Exposure to CW and PW had similar effects: it

studies have increased cell proliferation when measured shortly

provided evidence after exposure and decreased cell

that radiofrequency proliferation when measured 24 hr after irradiation.

(RF) The proliferative effects were independent of IL-2 The authors concluded that these

radiation concentration when measured immediately results are consistent with the

modulates after irradiation and cell proliferation decreased with hypothesis that 2,450-MHz RF 1) ↑+ (cell 1) ↑+ (cell

proliferation of cell vitality, cell increasing IL-2 concentration when measured 24 hr radiation affects CTLL-2 cell proliferation proliferation

gliomas, division, post-irradiation. In CLTT-2 cells, cultured without IL-

cell proliferation (measuring uptake external CEF; proliferation by altering membrane immediately after immediately after

fix no EXP in vitro morphological and no -/- nn nn sham-exposure ´-

of tritiated thymidine 3H-TDR) medium IMM lymphocytes, and 2 (which led to mitotic arrest of the cells) prior to signal transduction, a direct effect exp); 2) ↓+ (cell exp); 2) ↓+ (cell

other cell pathological

exposure, irradiation did not effect 3H-TdR uptake that is independent of heating. The proliferation 24h after proliferation 24h after

types but the changes

when measured immediately after exposure. This effect depends on the presence exp) exp)

mechanism of RF suggested that irradiation effects required the during exposure of unoccupied

radiation-induced presence of IL-2 receptors on the CTLL-2 cell high-affinity IL-2 receptors.

cell proliferation membrane. When assessed 24 hr after irradiation,

modulation is not 3H-TdR uptake occurred, but the extent of uptake

well understood. was smaller than in cells that had been cultured with

The authors IL-2 before irradiation. This indicated mitotically

investigated the

The authors arrested CTLL-2 cells retained their ability to

Except for a significant spectral shift in the

examined the frequency of Ca++

effects of cellular spikes in activated cells exposed to a simulated

phone GSM signal, revealed inthe fast Fourier transform of

radiofrequency calcium fluorescence variations over each

calcium ion (Ca++) levels and Ca++ (RF) 600-sec period in sham/exposed minus control

signaling patterns (regression slope fields on calcium period, there were no

ion (Ca++) levels The authors concluded that these

of Ca++ fluorescence, mean Ca++ significant differences in any of the examined Ca++

results provide no evidence that RF

concentration, number of Ca++ and Ca++ signaling parameters between ↑++(spectral shift of

fix nn EXP BMP in vitro patterns in Jurkat cell function no -/- nn emissions from cell phones are nn sham-exposure ´- ´-

spikes in each 10-min period, the cells exposed to either the CW RF fields or the Ca++spikes)

E6-1 cells, a associated with any changes in

mean height of the Ca++ spikes, simulated GSM signal.

human T- Ca++ concentrations or Ca++

and the average frequency of

lymphocyte signaling in lymphocytes.

the spikes)

hybridoma cell line.

Jurkat E6-1 cells,

obtained from the

American Type

Culture Collection,

were cultured in

The effect of heat Lenses heated for 5 min were almost as damaged

and microwave as those heated for 20 min at 41 C, suggesting that

irradiation on rat the initial heat shock is the critical factor in heat-

lenses was induced cataract formation.

investigated Controls at 39 C showed very small changes from

in vitro. Intact normal lens morphologic appearance in both

lenses in tissue epithelial and fiber cells, whereas progressive

culture medium damage (greater with PU than CW) occurred

EOR; were exposed to morphological and

depth of degeneration (by scanning external with increasing time of exposure. The maximum

yes nn EXP EYE; in vitro elevated pathological -/- yes nn nn nn controls (heated) nn ↑+ (lens damage) ↑++ (lens damage) amplification (pw)

electron microscopy) medium damage, observed at this temperature, occurred at

SEN temperatures for changes

the maximum PU time of exposure tested (20 min);

periods of up to 1 this involved the production of holes in the equatorial

hr, followed by lens fiber cells to a depth of approximately 80-100

incubation at 35.5 C um below the lens capsule.

for 2 days. The

maximum depth of

degeneration,

observed by

The scanning of

possibility Several kinds of damage were observed including Of several possible mechanisms

nonthermal effects holes in the fiber cells, capsular effects such as discussed, the authors conclude

of radiation in pitting or surface granulation, globular degeneration, that thermoelastic expansion,

microwave foam, and granulation of fiber cells. resulting in pressure waves

cataractogenesis Statistically significant greater damage was induced in the aqueous medium

was investigated observed for all combinations of PW radiation and lens tissue by thermoacoustic

by comparing the except one (23 mW/gm for 6 min) when expansion following each pulse of

effects of pulsed compared to CW radiation of the same average microwave energy, is the

damage of lense (by scanning (PW) morphological and

EYE; power. PW radiation produced 4.7 x the depth of mechanism most likely to

electron microscopy or light fix nn yes EXP in vitro or continuous pathological -/- yes nn nn nn nn ↑+ (lens damage) ↑++ (lens damage) amplification (pw)

SEN damage caused by CW radiation. The separate- explain the greater effects of PW

microscopy) (CW) radiation of changes

effects model provided slightly better fit to variation radiation. These results support

equivalent in depth of damage, but the authors feel the the concept of establishing lower

absorbed average reciprocal-effects model provides adequate fit for occupational exposure limits for

power practical purposes. PW than CW radiation, and may,

(temperature and in part, explain differences in safety

duration are standards established in Western

constant). Lenses and Eastern countries where

of Sprague-Dawley experimental work was performed

Therats

author Hematologic parameters such as hemoglobin mainly with CW and PW

summarized his levels and hematocrits were not affected by any

research on the irradiation. 37 days' exposure to PW caused larger

effects of low-level disturbances in iron metabolism and larger

microwave The author concluded that

decreases in RBC counts compared to CW.

radiation on the responses of blood and the blood-

Comparable changes in iron metabolism and RBC

hematopoietic forming system to microwave

counts due to CW irradiation were seen only after

system in various irradiation may reveal subtle '-(hematologic -(hematologic

Hematologic, such as hemoglobin 79 days of exposure.

experimental effects induced at low power parameters); ↕+ (iron parameters); ↕+ (iron

level and hematocrits; iron

nn nn nn EXP HCS in vivo animals. physiology -/- yes nn density levels. These types of nn sham-exposure nn metabolism); ↓+ metabolism); ↓++

metabolism (uptake of iron-59

Three groups of responses may represent a (RBC counts) after (RBC counts) after attenuation (pw)

(59Fe))

rabbits were convenient model for use in 37 days of exp 37 days of exp

irradiated with cytophysiologic studies and

continuous wave possibly biophysical investigations.

(CW) or pulsed

2,950-MHz

radiation for 2 hr

daily at the same

power density (3







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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn nn









possibly

nn

thermal









nn athermal









nn nn









nn thermal









thermal

nn (thermoelastic

expansion)









athermal

nn

(subtle thermal)









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









Center for

EFFECTS OF CONTIUOUS

Devices and

AND PULSED 2450-MHz

Czerska, E. M.; Radiological S-band wave guide

RADIATION ON

Elson, E. C.; Health; Bioelectro- (WR430, 109.22 mm 54.61 cell

SPONTANEOUS 100 - pulsed close to / cell culture

ockville, MD (E.M.C., M.L.S., P.C.); ElectricalEngineering Dept., Univ. of Maryland, College Park, MD (RR/C.C.D.); Dept. of Microwave Res., WalterReed Army Inst. of 2.45 Washington, DC (E.C.E.)

41 Czerski, P. Davis, C. C.; Univ. of USA 1992 magnetics 2.45 Res., none 100 1 1 nn nn up to 12,3/ up to 12,3 / cw = pw nn nn nn nn nn 1 (human nn nn cell

LYMPHOBLASTOID 1000 (square) above mm internally) (immune)

Swicord, M. L.; Maryland; 13(4) lymphocytes)

TRANSFORMATION OF fed by a common MW source

Czerski, P. Walter Reed

HUMAN LYMPHOCYTES IN

Army Inst. of

VITRO

Res.









BEHAVIORAL AND 0,4

0,6 0,6 5;

D'Andrea, J. A.; THERMAL EFFECTS OF MW 0,5

Radio Sci (CW (CW 3; 7,5; 0,51; 5,1 rat whole organism

ng, Univ. Utah, Salt Lake City,Gandhi, O. P.;

42 D'Andrea, J. A. Univ. Dept.Biology and Electrical USA

UT 84112 (J.A.D., O.P.G.); Utah RADIATION City, UT 84112

Engineering, Univ. Utah, Salt LakeAT RESONANT(J.L.L.)Radio Sci 12(6S):251-256

1977 0,7 1000 1000 3 pulsed nn nn cw ≥ pw above nn nn nn nn nn continuous 0 nn 3 whole body

12(6S) and and 30 10; /170 (Long-Evans) (behavior)

Lords, J. L. AND NONRESONANT (only

PW) PW) 20

WAVELENGTHS CW)









cell:

Dardanoni, L.; MILLIMETER-WAVE cell

Universita di J Bioelectr pulsed 7 cultures of the cell culture

43 Dardanoni, L. Istituto M. V.; Italy

Torregrossa, di Igiene, Universita di Palermo, Via del Vespro 133, 90127 Palermo,EFFECTS ON CANDIDA

1985 Italy 72 72 nn 1000 1000 nn nn / 0,0002 nn nn nn nn nn nn nn 3 hours multi continuous 0 (yeast, Candida nn 4 - 5 x 10

Palermo 4(1) (square) yeast Candida (colony-forming)

Zanforlin, L. ALBICANS CELLS albicans)

albicans









OPERANT BEHAVIOR AND

COLONIC TEMPERATURE

Naval Air Bioelectro- Styrofoam chair; monkey

OF MACACA MULATTA clearly 60-minutes-

44 de Lorge, J. O. Naval Aerospace Medical Res. Lab., Naval Air Station, Pensacola, FL 32508

de Lorge, J. O. Station, USA 1984 magnetics 1.3 1.3 370 370 3 3 pulsed nn 20-95 20-95 nn cw = pw nn nn temporary intermittent 0 (rhesus, Macaca nn 5 whole body whole organism

EXPOSED TO RF FIELDS AT above free-field radiation sessions

Pensacola 5(2) mulatta)

AND ABOVE RESONANT

FREQUENCIES









2 Generators: rats(30

Crit Rev 1) utilizing a minutes/day

Russian Acad.

Biomed Eng MIRA-2D for 7days);

of Sciences; EFFECT OF LOW-ENERGY

Devyatkov, N. D.; 29(1); pulsed X-ray mice (30 rat

"Extremely High AND HIGH-PEAK-POWER 5,6

Devyatkov, N. Pletnyov, S. D.; Bio- 30 mm 7,1 mm Yav1- unit, and 2) minutes/day (female); 50(rats)+ digestive; respiratory

Electronics, Russian Acad. of Sciences, Moscow, Russia (N.D.D.,O.V.B., V.V.F.); "Extremely2001 Frequency" Medical PULSES OF Assoc., Moscow, Russia (S.D.P.)

and 45 Frequency" Russia High NANOSECOND and Technical mm 6 6 0.01 0.01 pulsed 0.1 10 nn nn nn above nn nn temporary intermittent 0 female whole body

D. Betskii, O. V.; meditsinskay (PW) (CW) generator based for 4days, 1 mouse 77(mouse) (tumor)

Medical and MW RADIATION (CW)

Faikin, V. V. a Radio- on a "Sinus- day break (BDF-1)

Technical ON MALIGNANT TUMORS

elektronika G1" pulsed and for

Assoc.,

(10) accelerator further 5

design days)









NON-THERMAL DNA

BREAKAGE BY MOBILE-

Diem, E.;

Medical Univ. of PHONE RADIATION (1800 4; cell culture

Schwarz, C.; different mobile-

Vienna; MHz) IN HUMAN Mutat Res 1,2; mobile 16; continuous; ((human diploid cell culture

Medicine, Medical Univ. of Vienna,F.;

tional46 Diem, E. Austria

Adlkofer, Waehringer Guertel 18-20, Vienna 1090,Austria (RR/H.R., E.D., C.S., O.J.); Verum Foundation, Munich, Germany (F.A.)

2005 1.8 1.8 none 217 217 nn nn phone nn nn cw = pw above nn nn acute 1 nn nn cell culture

Verum FIBROBLASTS AND IN 583(2) 2 telephone 24 intermittent fibroblasts and rat (muscle-skeleton)

Jahn, O.; modulations

Foundation, TRANSFORMED GFSH-R17 hours granulosa)

Rudiger, H.

RAT GRANULOSA CELLS IN

VITRO









cell

Dutta, S. K.; LACK OF MICROBIAL (yeast:

2 hours (cw);

Nelson, W. H.; GENETIC RESPONSE TO J Microw 8,5-9,6 cw ≤ pw Saccharomyces; cell culture

47 Dutta, S.K. USA

Dept. Botany, Howard Univ., Washington, DC 20059

Howard Univ. 1979 2.45 9.6 1000 1000 nn nn pulsed nn 20 1 - 45 40 nn above nn nn nn nn 90 minutes acute continuous 0 nn nn cell

Blackman, C. F.; 2.45-GHz CW AND 8.5 - 9.6- Power 14(3) GHz cw ≥ pw bacteria: (bacteria)

(pw)

Brusick, D. J. GHz PULSED MW Salmonella typhi-

murium)









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



This investigation There were no significant differences in

attempted to distribution of cell sizes in control and sham-

resolve previous exposed cultures incubated 120 hr. A low level of

contradictory spontaneous lymphoblastoid transformation (1.2 +/-

findings by 37 and 37.5°C: ´-, 37 and 37.5°C: ´-

0.9/100 cells) was evident in pooled or control and

others regarding sham-exposed results. Distribution of cell sizes in ´-

the effects of The authors concluded that PW 38.5°C: ↑++ (cells

conventionally heated cultures subjected to

pulsed (PW) and 2450-MHz and CW 2450-MHz 38.5°C: ↑+, ↑+ 150-200 µm2;

increasing increments of heat showed no significant

of continuous (CW) microwaves delivered at the same (cells 150-200 ↓+ (cells 100-120 37 and 38°C: ↑++

HCS; (p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









ULTRASTRUCTURAL

STUDIES ON THE EFFECT

OF LOW FIELD INTENSITY Red kidney bean

Dwivedi, R. S.; MW RADIATION ON THE J Cell Biol 5; plants (Phaseolus whole organism

48 Dwivedi, R. S. Dept. Botany, USA

Howard Univ. Howard Univ., Washington, DC 1979 2.45 2.45 none nn nn nn nn pulsed nn 10

nn cw = pw above nn nn nn nn nn nn 0 nn nn whole body

Vaidya, C. B. MEMBRANES OF LEAF 83(2 Pt 2) vulgaris L., 1-4 wk (plants)

CELLS OF RED KIDNEY old)

BEANS (PHASEOLUS

VULGARIS L.)









Motorola Florida Bioelectro-

clearly rabbit; part: sensoric

49 Elder, J.A. Motorola Florida Research Laboratories, Ft. Lauderdale, Florida, USAOcular effects of RF energy

Elder, J.A. Research USA 2003 magnetics 2.45 2.45 none nn nn nn nn pulsed nn nn 150 cw = pw nn nn nn 30 minutes acute continuous 0 nn nn

above monkey eye (ocular system)

Laboratories 24 (6)









standard horn antenna

EFFECT ON THE IMMUNE

powered by a

Natl. Res. Inst. SYSTEM OF MICE pulsed 3 hours/day

Elekes, E.; Bioelectro- TK1 type TR-TK0603

for Radiobiology EXPOSED CHRONICALLY (square wave for 6 mouse

and Radiohygiene, Budapest, Hungary;Natl. Res. Inst. for Radiobiology and Radiohygiene, POB 101, H-1775 Budapest, Hungary (RR/E.E.)

rie" Res. Inst. for RadiobiologyThuroczy, G.;

50 Elekes, E. Hungary 1996 magnetics 2.45 2.45 none 50 50 nn nn nn 0,1/ 0,12 - 0,16/ cw = pw close to nn microwave generator coupled nn temporary intermittent 0 female, male nn whole body whole organism

and TO 50 Hz AMPLITUDE- amplitude consecutive (BALB/c)

Szabo, L. D. 17(3) to an OMSZOV

Radiohygiene MODULATED 2.45 GHz modulated) days

type BE-104 function

MICROWAVES

generator









HEART RATE CHANGES

cardio-vascular

Jauchem, J. R.; NASA-Lyndon DUE TO 5.6-GHz RF Proc Soc rat

250; 30; 6; (heart rate, blood

51 Frei, M. Branch, Mail Code SD3, NASA-Lyndon B. Johnson Space Center, Houston,RADIATION:

Medical ResearchR.;

Frei, M. R. B. Johnson USA 1984 TX 77058 Exp Biol Med 5.6 5.6 none 250 1 1-2 pulsed nn cw = pw above radar far-field nn acute intermittent 0 (Sprague-Dawley, female 28 whole body

500 60 12 pressure, respiratory

Heinmets, F. Space Center RELATION TO AVERAGE 177(3) adult)

rate)

POWER DENSITY









Trinity Univ. ; PHYSIOLOGICAL EFFECTS

J Microw 8,4;

Frei, M.; Sch. of OF 2.8 GHz RF RADIATION: 12,6; cardio-vascular

Power rat

v. (M.F.); Sch. of Aerospace Medicine, Brooks AFB, Aerospace

52 Frei, M. R. Jauchem, J.; USA Aerospace Medicine, Brooks AFB, TX (J.J.); Univ. of Texas,Austin, TX (F.H.)

TX (M.F.);Radiation Sciences Division, Sch. of1988 A COMPARISON OF 2.8 2.8 none 500 500 2 2 pulsed nn 30; 45; 60; 75 (pw) / cw membranes. Similar damage was caused by

nn nn nn EXP EOR mW/cm2. Small membrane function no -/- nn susceptibility to microwaves. The nn nn nn membranes of leaf membranes of leaf

chloroplasts vitro continuous and pulsed modes of radiation.

pieces of leaf results suggest that membranes chloroplasts) chloroplasts)

samples selected are the primary targets of

at random were microwave

prepared for irradiatio for nonthermal effects.

electron

microscopy after

glutaraldehyde-

osmium fixation.

The membranes of The nonhuman primate study showed that the

incident power density levels causing cataracts in

rabbits and other laboratory animals cannot be

directly extrapolated to primates, including

human beings (due to different facial structure). It is Clinically significant ocular effects,

reasonable to assume that an SAR that would including cataracts, have not been

induce temperatures 41°C in or near the lens in confirmed in human populations

ocular effects the human eye would produce cataracts by the exposed for long periods of time to

(cataracts, corneal lesions, retinal in or near EYE; changes of the

0 min at power densities causing extremely high dose rates (150 W/kg) yes temperatures (41°C) in or near the lens vivo

yes and EXP were not observed in the monkey eye exposedthat caused

in caused cataracts in the rabbit eye. However, cataracts no -/- same mechanism (heating) to similar exposure conditions, reflecting the different patterns ofThe results of four (SAR, specific absorption rate) distribution, due to their different facial structure. ´- (ocular effects) head is similareffects)

nn low level RF. energy absorption nn nn nn Since the monkey ´- (ocular in structure to the human head, the nonhuman primate study showed that the incident power density levels causing cataracts in rabbits and other laboratory anim

effects, changes in vascular the lens SEN neurological system cataracts in the rabbit lens; however, such an recent human studies show that

permeability) exposure would greatly exceed the currently there is no clear evidence of an

allowable limits for human exposure and would be association between RF exposure

expected to cause unacceptable effects in other and ocular cancer.

parts of the eye and face; some unconfirmed

effects: corneal lesions after CW; retinal effects

after PW;



The immunological Body weights were not affected by any microwave

effects of 50-Hz exposure. Spleen weights and the spleen index

square wave were moderately increased by 15% only in male ´- (spleen weights ↑+ (spleen weights;

amplitude increase (pw)

mice exposed to AM modulated microwaves, but the and index; male and male)

body weight; weight of spleens; modulated (AM) spleen index increase was not quite significant Spleen weights and female)

spleen index (defined 2.45-GHz or CW The authors concluded that 50-Hz

(p=0.0687). No changes in spleen weight or index the spleen index were

as ratio of spleen weight to body AM modulated and CW 2.45-GHz The lack of an effect in female amplification (pw)

2.45-GHz were induced by AM modulated microwaves in moderately increased ↑+ (plaque forming ↑++ (plaque forming

weight); number of splenocytes; microwaves were microwave radiation causes mice may be due to

female mice or by CW microwave radiation in by 15% only in male cell assay response; cell assay response;

hemagglutinin titers; evaluated in mice. moderate increases in antibody differences in

in vivo -> immunological mice of either sex. No exposure-related mice exposed to AM nn only male) only male)

IgG levels nn nn nn EXP IMM Male and female -/- yes production in male, but not female psychoneurohormonal shelf-control

vitro reactions changes in splenocyte counts were seen. modulated (´-)

BALB/c-mice were mice. The small response was regulation or differences in

The splenic PFC response to SRBCs was microwaves, but the ´- (splenocytes

The splenic response to SRBC exposed to attributed to the low power level of situational stress between

increased by 37.07% in male mice exposed to CW spleen index counts) ´- (splenocytes counts)

inoculation radiation 3 hr daily the and short duration of the males and females.

microwave radiation (from 15,343.3 +/- 1700.5 to increase was not quite

was determined using the plaque for 6 consecutive exposure.

21,031.2 +/- 2517.6 PFC/spleen, p=0.0929) and by significant (p=0.0687). ´- (serum ´- (serum

forming cell (PFC) assay. days. 55.41% in males exposed to modulated radiation hemagglutinin titer, hemagglutinin titer,

The time averaged (from 11,980.4 +/- 1437.4 to 18,619.0 +/- 3136.2 IgG, body weight) IgG, body weight)

power density was PFC/spleen, p=0.0918), differences which the

0.1 mW/cm2 and authors considered significant. This parameter was

the whole body

This study was No significantly affected in female mice.

not differences were observed between results

designed to obtained with pulsed and continuous wave

investigate effects exposures. Heart rate increased at exposure to 60

on heart rate, blood mW/cm2, and not to 30 mW/cm2. The time taken

pressure, and to reach a colonic

respiratory rate of temperature of 39.5 C was over twice as long at 30

5.6 GHz mW/cm2 as at 60 mW/cm2,

radiofrequency but the time taken to return to 38.5 C was similar. The authors doubt that exposure

blood pressure; respiration; CVS; radiation (RFR) at No changes in mean arterial blood pressure or to these RFR conditions would ↑+ (heart rate at 60 ↑+ (heart rate at 60

yes colonic yes EXP in vivo power densities of physiology no -/- nn nn nn nn

EKG RES in respiratory rate were observed. have any serious long-term mW/cm2) mW/cm2)

30 and 60 physiological consequences

mW/cm2,

exposure

conditions

characteristic of

high-power

stationary tracking

radars for military

applications and of

The acute No significant difference in heating or cooling ´- (heating or cooling

´- (heating or cooling

thermophysiological responses were seen between the PW- and the responses)

responses)

effects of CW-RFR exposed animals at any of the power

exposure to PW The authors conclude, however, ´- (respiratory rate)

densities tested. Average power density was

that no significant difference was ´- (respiratory rate)

radiofrequency inversely related to the time to achieve the 1 C

radiation (RFR) shown between the effect of acute ↓+ (blood pressure)

colonic temperature increase; however, the time to

Heart rate was slightly CW or PW RFR exposure upon ↓+ (blood pressure)

chamber were compared to recovery of the baseline temperature was increase (pw)

arterial blood pressure; those of exposure decreased but not the anesthetized rat's colonic ´- (heartrate)

unaffected. No linear relationship exists between

respiratory rate; CVS; significantly changed thermal response, heart rate, ↑+ (heartrate; ≥ 30

colonic; to CW RFR in physiology; power density and core temperature increase; this is 2

ECG; yes yes EXP RES; in vivo ketamine- -/- yes during 30-mW/cm2 arterial blood pressure, or nn nn nn mW/cm )

tympanic; thermoregulation in contrast to a cadaver or saline model. Heart rate amplification (pw)

temperature (colonic, TMP anesthetized rats. pulsed irradiation. respiratory rate. The differential in ↑++ (tympanic,

subcutaneo was slightly decreased but not significantly changed

subcutaneous, tympanic)

us Female Sprague- during 30-mW/cm2 pulsed irradiation. Heart rate

the effects of PW and CW RFR on subcut. temperature) ↑+++ (tympanic,

Dawley rats were subcutaneous and tympanic subcut. temperature)

significantly increased during PW-RFR exposure

exposed in the heating did not, it is concluded, ↑+ (colonic

in an inverse relationship to power density at amplification (pw)

far-field to 2.8-GHz significantly alter the colonic temperature) ↑++ (colonic

values greater than 30 mW/cm2. Heart rate was

PW (2 usec, 500 heating and cooling responses. temperature)

not affected significantly during CW RFR

pps) and CW RFR exposure at the different power densities. Mean ↕+ (changes within

at average power blood pressure decreased slightly during the temperature change (cw)

densities ofmale45, 2

Twenty 30, The times required for Tc to increase from 38.5 cycles; 60-mW/cm )

Sprague-Dawley to 39.5 C under each of the exposure conditions

rats, weighing were nearly equal during CW and pulsed

between 304-361 exposure in either orientation; but the time

g, were required for E-orientation exposure was

anesthetized with ↑+ (colonic; ↑+ (colonic;

significantly longer (2-3 times) than for H-

ketamine HCl tympanic; tympanic;

orientation. H-orientation exposure produced faster

(Velatar) and were subcutaneous subcutaneous

ECG; arterial blood press.; colonic; Tc increases (except for the tail), higher local SHR in

CVS; exposed temperatures) temperatures)

respirat. rates; tympanic; physiology; the anesthetized rats, and higher local SAR in the

yes yes EXP RES; in vivo individually in E no -/- nn nn nn nn nn

temp. (left and right sub-cutaneous, subcutaneo thermoregulation rat carcasses. During Tc increases from 38.5 to 39.9

TMP (long axis parallel ↑+ (heart rat, blood ↑+ (heart rat, blood

right tympanic, colonic, tail) us C, heart rate and blood pressure increased, but

to electric field) pressure) pressure)

there were no differences in these changes between

and H (long axis the effects of E- and H-orientation exposure or

parallel to a ´- respiration rate ´- respiration rate

between CW and pulsed irradiation. The respiratory

magnetic field) rate did not change significantly under any exposure

orientations to both conditions.

CW and pulsed

radiofrequency

radiation









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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn athermal









nn thermal









nn nn









nn thermal









yes

(blood thermal

pressure)









nn thermal









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









model 1326 thermo-regulatory

THERMOREGULATORY Radiat RF power (thermo-regulatory-

Frei, M. R.;

Trinity Univ.; RESPONSES OF RATS Environ 30; 30; 9,3; 9,3; source model 2852 rat regulatory responses

. of Biology, Frei, M. R. 715Jauchem, Dr., San Antonio, TX 78284 (F.H.); RadiationSciences Div.,1989

54 Trinity Univ., Stadium J. R.; USA USAF/SAM, Brooks AFB, TX 78235 (M.R.F., J.R.J.) 9.3 9.3 none 500 500 2 2 pulsed nn cw = pw above radar far-field nn acute intermittent 0 female 6 whole body

USAF/SAM EXPOSED TO 9.3-GHz RF Biophys 60 60 18,6 18,6 (Cober power source (Sprague-Dawley) and related

Heinmets, F.

RADIATION 28(1) Electron.), physiological

far-field processes)









0,6 / 200

AVOIDANCE BY RATS OF 100 (exp.1)

J Comp

Frey, A. H.; (no affiliation ILLUMINATION WITH LOW (exp. 1); 30 whole organism

55 Frey, A. H. (no affiliation given) USA 1975 Physiol 1.2 1.2 none 100 30 pulsed nn 2,4 (exp.2) nn cw > pw above nn nn nn nn acute continuous 0 rat nn nn whole body

Feld, S. R. given) POWER NONIONIZING EM 1000 5000 0,2 / 2,1 (behavior)

Psychol 89(2)

ENERGY (exp.2) (exp.2)









30 minutes,

standard horn antenna female (1. whole body (1. nervous

NEURAL FUNCTION AND 4 times/day

Frey, A. H.; experiment) experiment) (central

BEHAVIOR: Ann N Y (Model 411A rat

56 Frey, A. H. Feld, S. R.; Randomline, Inc. Huntingdon Valley, PA 19006 1975

Randomline, Inc., USA 1.22 1.22 none 1000 1000 500 500 pulsed nn 2.4 0,2 / 2,1 nn cw > pw above nn Microdot power oscillator was far-field acute intermittent 0 nn nervous system

DEFINING THE Acad Sci 247 30 minutes (Sprague-Dawley)

Frey, B. male (2. head (2. function and behavior;

RELATIONSHIP fed to the antenna) (2.

experiment) experiment) BBB)

experiment)









0,65;

0,2;

EXPOSURE TO RF standard gain

Randomline, 0-0,1 cw = pw (0.2); above / rat 16;

Frey, A. H.; ELECTROMAGNETIC Aggressive 100; horn antenna; 5 whole organism

57 Frey, A. H. USA

Randomline, Inc., County Line and Mann Roads, Huntingdon Valley, PA 19006

Inc., Huntingdon 1986 1.3 1.3 none 1000 1000 100 pulsed nn 0.2 / nn cw pw close to male) 60

AGGRESSIVE BEHAVIOR. chamber

0,4;

0,05 - 0,2









Fritze, K.; Max-Planck-Inst.

EFFECT OF GLOBAL

Sommer, C.; for Neurological

SYSTEM FOR MOBILE

Schmitz, B.; Res.; Acta below / plastic tubes

COMMUNICATION (GSM) rat nervous

eler Strasse 50,D-50931 Cologne, Germany (K.F.,Ruprecht-Karls-

58 Fritze, K. Mies, G.; Germany

B.S., G.M., K.A.H.); Inst. for Neuropathology, Ruprecht-Karls-Univ.,Heidelberg, Germany Neuropathol Novartis Pharma Inc.,none

1997 (C.S., M.K.); 0.9 0.9 Nervous Syst. Res., Basel, Switzerland(C.W.)

217 217 nn nn GSM-like nn nn 7.5 0,3; 1,5(brain) cw > pw close to / nn in a circular carousel, near-field 4 hours acute continuous 0 male 4 x 20 whole body

MW EXPOSURE ON (Wistar) (BBB)

Hossmann, K. A.; Univ.; (Berl) 94(5) above heads facing a central antenna

BLOOD-BRAIN BARRIER

Kiessling, M.; Novartis

PERMEABILITY IN RAT

Wiessner, C. Pharma Inc.









sleeved sleeved dipole

dipole antenna antenna

Fritze, K.; Max-Planck-Inst. whole body: fed by a fed by a

Wiessner, C.; for Neurological EFFECT OF GLOBAL 0,17; signal commercial

Kuster, N.; Res.; SYSTEM FOR MOBILE 0,84; synthesizer GSM phone

1; below /

Sommer, C.; Ruprecht-Karls COMMUNICATION MW Neuroscience 4,2 (HP8656) (Motorola rat histological cut

Germany Germany (C.S.,P.G., M.K.); Lab. of EMF and Microwave Electronics, Swiss Federal Inst. of Tech. 217

rmany (K.F.,C.W., D.M.H., RR/K-A.H.); Inst. of Neuropathology, Ruprecht-Karls Univ., Heidelberg,1997

59 Fritze, K. 0.89 0.915 0,9 (cw) 217 (ETH), Zurich,Switzerland (N.K.)

nn nn GSM-like 5; nn cw = pw close to / nn near-field 4 hours acute continuous 0 male nn whole body

Gass, P.; Univ.; EXPOSURE ON THE 81(3) brain: International (Wistar) (nervous)

25 above

Hermann, D.M.; Swiss Federal GENOMIC RESPONSE OF 0,3; 2000)

Kiessling, M.; Inst. of Tech. THE RAT BRAIN 1,5; controlled by

Hossmann, K-A. (ETH) 7,5 / a GSM RF

test set

(HP8922A)









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



Research on the At both power densities the sc and tympanic

biological effects of temperature increases significantly exceeded the

gigahertz colonic temperature

radiofrequency increase. Furthermore, heart rates increased

radiation significantly during RFR

(RFR) suggests exposure (both CW and pulsed) and returned to The authors

that acute normal upon cessation of interpreted their results as

respiratory rates; arterial blood colonic; exposure to high exposure. Neither blood pressure nor indicative of a marked effect of ↑++ (sc and tympanic ↑++ (sc and tympanic

CVS; levels of RFR in

pressure; tympanic, sc, and colonic tympanic; physiology; respiratory rate changed carrier temp; heart rate); ´- temp; heart rate); ´-

yes yes EXP RES; in vivo this frequency no -/- nn nn nn nn

temperatures subcutaneo thermoregulation significantly during RFR exposure. No significant frequency upon the pattern of heat (blood preassure, (blood preassure,

TMP range may induce

us differences in the distribution and physiological resp. rate) resp. rate)

both morphological effects of CW or pulsed RFR were noted. As responses

and/or functional compared to previous studies elicited in RFR-exposed animals.

changes in diverse conducted at a frequency of 2.8 GHz, the levels of

biological systems. sc heating and heart

Most of this rate change were greater and latencies for 1-degree

research, however, colonic heating and

has utilized RFR in cooling were increased at both power densities at

the spent more

Rats frequency 9.3 GHz.

1. experiment:Rats spent more time in the halves of

time in the halves shuttle boxes that were shielded from illumination by

of shuttle boxes 1.2 GHz microwave energy than in the unshielded.

that were shielded

from 2. experiment: The rats avoided the pulsed energy,

illumination by 1.2 but not the continuous energy.

GHz microwave

energy than in the

unshielded. In nn ´- (time spent in the ↑+ (time spent in the

time spent in

nn nn nn EXP BEH in vivo Experiment 1, rats behaviour -/- yes nn nn nn (shielded shuttle nn shielded halve of the shielded halve of the increase (pw)

the shielded half of the shuttle box

avoided the energy boxes) shuttle box) shuttle box)

when it was

presented as 30-

musec

pulses with a pulse

repetition rate of

100 pulses per

second (pps). The

average power

The authors 1. experiment: No significant differences in time The authors concluded that

examined the spent in the shielded half of the shuttle box were irradiation of small mammals with

effects of seen for the first 2 days of the experiment, however low power RF energy affects

radiofrequency differences emerged by the third and fourth days. BBB integrity. Because parts of

(RF) radiation on The group exposed to the pulsed radiation the body other than the brain were ↑+ (time spent in the

central spent, on average, 30% of its time in the 1. experiment: time irradiated, it cannot be stated shielded half of the

nervous system ´- (time spent in the

unshielded half of the box, the sham irradiated spent in the shielded decisively that the observed shuttle box;

time spent in in vivo (1. (CNS) function and shielded half of the increase (pw)

group spent 52% of its time, and the group half of the shuttle box: changes in BBB permeability differences emerged

the shielded half of the shuttle box BBB; experiment) behavior. The morphological and shuttle box)

exposed to CW radiation spent 64% of its time in the difference between were a direct result of RF by the third and fourth

(1. experiment) nn nn nn EXP BEH; in vivo -> purpose of the pathological -/- yes nn sham-exposure ´-

the unshielded half of the box. The difference the CW group and the exposure. The effects could be a day of experiment)

NES vitro (2. experiments changes; behaviour ↑+ (fluorescein

between the group exposed to the pulsed radiation sham irradiated group secondary to irradiation of some

BBB permeability (2. experiment) experiment) was to determine if staining, BBB amplification (pw)

and the sham irradiated group and between the was not statistically other part of the body. ↑++ (fluorescein

there was an permeability)

pulsed and CW irradiated groups was statistically significant. Nonetheless, it appears that RF staining, BBB

association significant (both at p=0.013) while the difference energy affects brain permeability)

between changes between the CW group and the sham irradiated permeability and behavior and

in CNS group was not. that pulsed RF energy is more

function and effective than CW radiation in

avoidance 2. experiment: The intensity of fluorescein doing this. The results also

behavior and

Based on earlier The EM in the sections and reduced

stainingexposure substantiallythe number of

work which points aggressive behavior at incident average power

to the dopamine densities of 50 and 100

(DA) and opiate uW/cm2, as did the CW exposure; 20 uW/cm2 was

systems not effective. The pulse

of the brain as width did not appear to be critical.

being mediators of the authors hypothesize that

electromagnetic aggression induced by aversive

(EM) irradiation stimulation would be modified ↓++ (aggressive ↓++ (aggressive

aggressive behavior nn nn nn EXP BEH in vivo effects, the authors behaviour no -/- nn nn sham-exposure ´-

by exposure of the animals to behaviour) behaviour)

hypothesize that low-intensity

aggression induced EM energy.

by aversive

stimulation would

be modified by

exposure of the

animals to low-

intensity

EM energy.

The authors In the brains of freely-moving control rats, only 1 The authors concluded that

examined the spot of extravasated serum albumin was seen in a microwave irradiation of the brain

effects of single animal. In the 20 sham- exposed controls, at frequencies and intensities

microwave 4 circumscribed extravasation areas were seen in 3 corresponding to cellular

radiation with the animals. In microwave-irradiated animals, 5 out of telephones produces no or only

characteristics of 10 animals irradiated at SARs of 0.3, 1.5, and 7.5 negligible permeability changes in

global system for W/kg that were killed at the end of exposure showed the BBB. The observed changes

extent of immunohistochemical mobile stat. insignificant are not associated

7, 6, and 14 extravasation areas, respectively. In

staining for extravasated morphological and increase in the

in vivo -> communications the 10 animals in the 0.3, 1.5, and 7.5-W/kg groups with any lasting histological sham exposure/ ↑++ (extravasation ↑++ (extravasation ↑++ (extravasation

serum albumin nn nn nn EXP BBB (GSM) signals on pathological no -/- extravasation areas at damage. These data, therefore, nn

vitro that were killed 7 days after exposure ended, the shelf control areas) areas) at 7.5 W/kg areas) at 7.5 W/kg

=> blood-brain barrier changes 0.3 and 1.5 W/kg do not support the view that use of

total number of

BBB permeability (BBB) permeability exposures cellular phones presents a health

extravasation areas was 2, 0, and 1, respectively.

in rats. Groups of The microwave-induced increases in number of risk to the

20 serum albumin extravasation areas was brain. The authors noted that the

unanesthetized statistically significant only for the group limited extravasation was seen only

male Wistar rats exposed at SAR of 7.5 W/kg. The size and at the highest exposure level (7.5

were irradiated for appearance of the extravasation areas were very W/kg) which is close to the

4 hr with 900-MHz similar regardless of the radiation intensity or the threshold for

microwave

The authors time of investigation. No evidence of histological

In the positive controls, marked induction of the thermal effects, occurred in

The authors concluded that 4-hr

examined the mRNAs was observed, confirming the reliability of exposure to microwave

effects of the in-situ hybridization technique. Immediately after radiation at SARs ranging up to 7.5

microwave exposure, slight induction of hsp 70 mRNA was W/kg did not produce any major

exposures seen in the cerebellum and abnormalities in gene expression in

produced by the hippocampus of rats exposed to the 7.5-W/kg the rat brain. Lasting tissue

hsp 70, c-fos, c-jun, and glial Global System for radiation, but this was not reactions to these types of

fibrillary acidic protein (GFAP) Mobile 1) ↑+ (induction of 1) ↑+ (induction of

observed at lower intensities. A slight increase in exposures are, therefore, unlikely. 1) ´- (induction of

mRNA (in-situ hibridization); Communications hsp 70 mRNA at 7.5 hsp 70 mRNA at 7.5

in vivo -> molecular c-fos mRNA expression was seen in the It cannot sham-exposure / hsp 70 mRNA);

expression of C-FOS, FOS-B,C- yes rectal no EXP CEF no -/- nn nn W/kg); W/kg);

vitro (GSM) on gene biosynthesis cerebellum, neocortex, and piriform cortex of all be stated with absolute certitude shelf control 2) ↑+ (induction of

JUN, JUN-B, HSP, KROX-20 expression in rat 2) ↑+ (induction of c- 2) ↑+ (induction of c-

animals that had been immobilized (sham- that mobile telephones do not c-fos mRNA);

(immunocytochemical technique); brain. Male Wistar fos mRNA); fos mRNA);

irradiated controls and irradiated animals); present a

cell proliferation rats were exposed however, there were no differences in c-fos mRNA health risk to the central nervous

to a GSM expression among the different irradiated groups. c- system since the effects of chronic

microwave signal Jun and GFAP mRNA expression was not microwave exposure and of

at antenna increased in any irradiated group. No changes in microwave exposures combined

powers of 1 or 5 W the level of expression with other noxious

or to 25-W 900- of any of the immediate early gene-encoded conditions were not examined.

MHz continuous proteins and stress proteins,









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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









yes thermal









nn nn









nn nn









yes nn









nn nn









nn nn









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









THE ABSENCE OF cell:

SIGNIFICANT SHORT-TERM giant internodal

EM IEEE Trans cells of

Gokhale, A. V.; electrolyte

Washington BIOEFFECTS IN GIANT Microw 8,4 - 0,00001; 0,1; close to / cell eukaryotic

60 Gokhale, A. V. Dept. of USA

Brunkard, K. M.; Electrical Engineering, Washington Univ., Saint Louis, MO 63130

1984 8.4 12.4 0.00001 0.1 pulsed nn 0,1 - 10 0,1 - 10 nn cw = pw nn culture near-field nn nn nn 0 nn nn cell

Univ. ALGAL CELLS EXPOSED TO Theory Tech 12,4 0,001 1 above (green alga) green algae

Pickard, W. F. apparatus

CW AND PULSE- 32(8) Chara braunii

MODULATED X-BAND and Nitella

BURSTS flexilis









VHF;

EVIDENCE THAT

UHF; cell

Univ. CHARACEAN MEMBRANE

Gokhale, A. V.; Radiat Res X-band close to / (single giant of the

61 Gokhale, A. V. USA

Dept. of Psychiatry, Washington Univ. Sch. of Medicine, Saint Louis, MO 63110

Washington 1985 TRANSPORT IS NOT 0.05 0.917 nn nn nn nn pulsed nn 0,01 - 500 nn cw = pw nn flow channel nn nn nn continuous 0 nn nn cell cell

Pickard, W. F. 102(3) e.g. above algae Chara braunii

Sch. Medicine SIGNIFICANTLY ALTERED

147; and Nitella flexilis)

BY INCIDENT EM RADIATION

450









ABSENCE OF MW EFFECT rat

Gruenau, S. P.; 1;

ON BLOOD-BRAIN BARRIER 10; (Tac:N[SD]sBR,120

Oscar, K. J.; Naval Medical Exp Neurol 5; cw = pw (40); nervous

62 Gruenau, S. P. Naval Medical Research Inst., Bethesda, MD 20014

USA 1982 PERMEABILITY TO 2.8 2.8 none 500 500 2 2 pulsed nn 40 nn above nn nn 30 minutes acute continuous 0 -150 male nn whole body

Folker, M. T.; Research Inst. 75(2) 10; cw > pw (BBB)

[14C]SUCROSE IN THE days old, weighing

Rapoport, S. I. 15

CONSCIOUS RAT 250-300 g)









0,2712

cell cell culture

Anderstam, B.; (CW-

STUDIES OF POSSIBLE 4 (RF); (strains of (mutation of

Hamnerius, Y.; Univ. of Hereditas electric 3,07 2,45

63 Hamnerius, Y. Sweden

Dept. of Radiobiology, Wallenberg Lab., Univ. of Stockholm, Sweden GENETIC EFFECTS IN

1983 nn nn nn nn pulsed nn nn 35 - 100 cw = pw above nn nn far-field 1 - 7 hours temporary continuous 0 Salmonella nn 13 strains cell Salmonella

Hussain, S.; Stockholm 98(1) and (PW) (CW)

BACTERIA OF HF EMF (MW) typhimerium and typhimerium and

Ehrenberg, L. magneti

Escherichia coli) Escherichia coli)

c)









0,2712

(CW- cell

BIOLOGICAL EFFECTS OF

electric pulsed or (Salmonella

Hamnerius, Y.; HF EMF ON SALMONELLA Bioelectro- modified version of the Ames

Chalmers Univ. and 3,1 2,45 amplitude typhimurium cell culture

64 Hamnerius, Y. Applied Electron Sweden

Rasmuson, A.; Physics, Chalmers Univ. of Technology, S-412 96 Gothenburg, Sweden

1985 TYPHIMURIUM AND magnetics 500 500 1 1 nn nn nn nn nn nn test far-field (PW) nn nn nn 0 nn nn cell

of Technology magneti (PW) (CW) modulated (2.45 cultures; Drosophila (genetic damage)

Rasmuson, B. DROSOPHILA 6(4)

c, GHz) melano-gaster

MELANOGASTER.

Drosoph embryos)

ila only)









Nilsson, R.; Univ. of

Hamnerius, Y.; Goteborg; MW EFFECTS ON THE

4

Hansson Mild, K.; Chamlers Univ. CENTRAL NERVOUS

Health Phys 4 hours/day monkey (2 pw

65 Hamnerius, Health, S-901 87 Umea, Sweden (K.H.M.); Inst. ofNeurobiology, Univ. of Goteborg, Box 33031, S-400 33 Goteborg, Sweden (H-A.H.); Dept. of2.45

al Inst. of Occupational Y. Hansson, H-A.; of Technology; Sweden 1989 SYSTEM -- 2.45 Neurology,Univ. of Goteborg, Sahlgren Hosp., S-413 45 Goteborg, Sweden (E.H., L.I.P.); Dept. of PsychiatryIII, Univ.2,6 Goteborg, Lillhagen Hosp., Box 3005, S-422above

none nn nn nn nn pulsed nn 10 10 of - 4,8 2,6 - 4,8 cw = pw 03 Goteborg, Sweden (S.O.)

radar nn nn temporary intermittent 0 nn whole body nervous

56(5) on 12 days (cynomolgus) 1 cw

Hjelmqvist, E.; National Inst. of A STUDY OF RADAR

1 control)

Olanders, S.; Occupational MECHANICS

Persson, L. I. Health;









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



In an attempt to In no instance was a

detect short term significant radiation-correlated offset of the resting

effects of low-level potential observed.

X-band frequency

microwave

irradiation on

cellular function,

the vacuolar The authors conclude that there

resting potential appears to be no simple, rapid,

´- (electrical effect on ´- (electrical effect on

vacuolar resting potential nn nn EXP BMP in vitro of the giant membrane function no -/- nn obvious nn nn nn

the resting potential) the resting potential)

internodal cells of electrical effect of X-band

eukaryotic green irradiation in this preparation.

algae Chara

braunii and

Nitella flexilis was

measured with

glass

microelectrodes.

Cells from Chara

The authors have No radiation-correlated

continued their changes of vacuolar resting potential or noise which

ongoing study of were attributable to

single giant cells of intermediate or long-term irradiation were observed

the at any of the

algae Chara frequencies tested.

braunii and Nitella

flexilis in an

attempt to detect ´- ( vacuolar resting ´- ( vacuolar resting

vacuolar potential nn nn nn EXP BMP in vitro membrane-related membrane function no -/- nn nn nn nn nn

potential) potential)

electromagnetic

bioeffects in a well-

defined cellular

system. The

exposure

apparatus

consisted of a

narrow silver

microstrip

The possible effect Regardless of the power density level of the MW,

of microwave the PA values did

(MW) radiation on not show significant differences from the respective The findings indicate that MW

blood-brain barrier regional values of irradiation

(BBB) sham-irradiated control animals. under the given experimental

permeability was conditions does not damage the

investigated in BBB. It is suggested that the dual

adult male rats compartment technique is

(Tac:N[SD]sBR; morphological and considerably more sensitive than

permeability-capillary surface area in vivo -> ´- (BBB

nn nn nn EXP BBB 120-150 pathological no -/- nn other existing techniques for the nn sham ´- (BBB permeability) ´- (BBB permeability)

product (PA) for [14C] sucrose vitro permeability)

days old, weighing changes measurement of cerebrovascular

250-300 g). The permeability. With [14C]sucrose

permeability- as the test tracer, this technique

capillary surface gives results that are independent

area of regional cerebral blood flow

product (PA) for which may increase in response to

[14C]sucrose was MW exposure.

examined at the

BBB of

Thirteen strains of No difference was seen in pooled mutation

Salmonella frequency between

typhimerium and exposed and control organisms for all exposures

Escherichia coli and strains. Growth

were exposed stimulation was observed in some situations and a

to high frequency weak prophage inducing The authors attempt to extrapolate

electromagnetic capacity was noted. the results to the ´- ↑+ (growth ↑+ (growth

cellular growth rate; (EM) fields in an situation of occupational exposure stimulation; prophage stimulation; prophage

attempt to discover cell vitality, cell

forward mutation, backmutation, or CEF; to EM fields in Sweden and inducing inducing

fix nn no EXP in vitro athermal effects. division; no -/- nn nn sham

prophage GEN estimate a capacity) capacity)

EM fields included genotoxicity

induction cancer risk, and risk of heritable

27.12 MHz damage, of less than 1 case ´- (mutations) ´- (mutations) ´- (mutations)

continuous wave annually.

(CW)

electric field, 27.12

CW magnetic field,

2.45 GHz CW EM

far field, and 3.07

GHz pulsed EM far

Radiofrequency In Drosophila- no effects. In bacteria-

electromagnetic significantly higher cell density after exposure to

radiation (EMR) 27.12 MHz magnetic field, 2.45 GHz CW and 3.10

has been reported GHz pulsed microwave radiation, without a

to induce corresponding increase in mutant cell numbers. The authors conclude that their

genetic damage in results

various types of demonstrate no genetic damage,

eukaryotic cells, cell vitality, cell

but a distinct non-thermal ´- (mutation in ´- (mutation in

somatic mutagenicity (Drosophila); division;

CEF; but questions physiological drosophila); ↑++ drosophila); ↑++

number of reversion mutations fix ext medium no EXP in vitro remain teratogenity; no -/- nn nn sham ´-

GEN effect on bacterial growth with (bacteria cell density; (bacteria cell density;

(bacteria); cell density (bacteria) regarding the genotoxicity

exposure to high frequency EMR, ´- (bacteria mutation) ´- (bacteria mutation)

importance of the as has been

temperature rise in reported by others for other genera

the test system in of bacteria and in yeast.

producing this

genetic effect. The

aim of this study

was to determine if

genetic damage

The possibility of The monkey exposed to 2.45 GHz PW MW at 10 The authors point out that the

central nervous mW/cm2 for 4 hr/day on 12 consecutive days (SAR clinical significance of the CSF

system effects in of 2.6-4.8 W/kg) exhibited an increase in a protein protein difference is not clear, but

radar mechanics band with a pI of 4.5. Only a faint band was seen the surprisingly high time derivative

and in the CSF from the monkey exposed to CW MW of the magnetic fields close to

engineers of the same power density and duration. The band some of the transmitter units

occupationally was absent or weak in CSF from the unexposed indicates that engineers and

exposed to monkey and from the monkey exposed to PW mechanics may be exposed to

EOR; microwaves (MW) morphological and radiation for only 2 days. magnetic flux density levels a ´- / ´- (protein

proteins in cerebrospinal fluid nn nn nn EXP in vivo was investigated pathological -/- yes nn nn shelf control ↑+ (protein band) ↑++ (protein band) amplification (pw)

NES thousand times higher than those band)

clinically in 17 changes

measured in front of video display

subjects (mean terminals. The authors suggest

age 52 yr). that the time derivative factor

Seventeen men should be controlled in future

with probable animal and epidemiological

exposure to studies and the effects of CW and

moderate or high PW MW radiation should be

levels of MW differentiated.

radiation, and 12









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Werner Alsbach / Jürgen Zschernitz / Margarita Simeonova Ausdruck vom 11/16/2011

Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn nn









nn nn









nn nn









nn athermal









nn athermal









yes nn









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Seite 27 von 100

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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









THE EFFECT OF 2450-MHz 2 minutes -

National Inst. Hewlett Applied embryo

Hamrick, P. E.; MW IRRADIATION ON THE Health Phys 1 hour, cardio-vascular

66 Hamrick, P. E. National Inst. Environmental Health Sciences, Research Triangle 1980 NC 27709

Environmental USA Park, 2.45 2.45 none 10 10-50 10 10 pulsed 0.1 - 10 nn 0.3-30 cw = pw above nn Packard Microwave nn acute continuous 0 (Japanese quail, 8- nn nn whole body

McRee, D. I. HEART RATE OF 38(3) typical (heart rate)

Health Sciences mode 18690B PH 49k 13 day old)

EMBRYONIC QUAIL 5-10 minutes









1 sec.

on 1

sec. off;



3 sec.

Haugh, C.; PULSING MW ENERGY: A on, 3

J Interv Card

Davidson, E. S.; Tufts Univ. Sch. METHOD TO CREATE MORE sec. off; cw = pw medical ovine endocardial

67 Haugh, C. USA

Cardiac Arrhythmia Service, New England Medical Center, Tufts Univ. Sch. of Medicine, Boston, MA02111 none

1997 Electrophysiol 0.915 0.915 nn nn nn pulsed 20 nn nn nn nn nn 30 seconds acute continuous 0 nn nn model system physical model system

Estes, N. A., 3rd; of Medicine UNIFORM MYOCARDIAL (20 W) application model

1(1)

Wang, P. J. TEMPERATURE GRADIENTS 5 sec

on, 5

sec off



with 30

sec









CHRONIC EXPOSURE TO 50-

Heikkinen, P.; Hz MAGNETIC FIELDS OR 1,5

Univ. of Kuopio;

Kumlin, T.; 900 MHz EMF DOES NOT Electro Wavetek signal generator; hours/day

Natl. Public mouse neuro-endocrine

Laitinen, J. T.K., J.J.); Dept. ofPhysiology, Univ. of Kuopio, Kuopio, Finland (J.T.L.); Lab. NOCTURNAL Natl. Public HealthInst., Kuopio,0.902 (H.K.)

Univ. of Kuopio, Kuopio, Finland (RR/P.H.,T.;

68 Heikkinen, P. Finland 1999 ALTER of Toxicology, Magnetobiol 0.902 Finland none 217 217 nn nn GSM-like nn nn 1.5 0.35 cw > pw above nn 5 days/week chronic intermittent 0 female nn whole body

Health rectangular waveguides (CBA/S) (melatonin)

Komulainen, H.; 6-HYDROXYMELATONIN 18(1) lasting 17

Inst.

Juutilainen, J. SULFATE SECRETION IN months

CBA/S MICE.









Heikkinen, P.;

Univ. of Kuopio;

Kosma, V-M.;

Kuopio Univ.

Hongisto, T.;

Hosp.; phone for the 1,5

Huuskonen, H.;

Natl. Public EFFECTS OF MOBILE analog Nordic hours/day

Hyysalo, P.; 6,1 (CW)

Health Inst.; PHONE RADIATION ON X- Radiat Res Mobile 5 mouse whole organism

Safety Authority, Helsinki, Finland (P.H.,L.P.); Dept. of Applied Physics, Univ. of Kuopio, and Dept.2001

69 Heikkinen, P. Komulainen, H.; Finland of Radiotherapy, Kuopio Univ. Hosp.,Kuopio, Finland (T.L.); Dept. of Environmental Sciences, Univ. of Kuopio, Kuopio, Finland (S.L.);Nokia Res. Center, Helsinki, Finland; Hyysalo, PricewaterhouseCoopers, Espoo, Finlandpw

0.902 0.902 none 217 217 nn nn GSM-like and 1,3 nn 1.5 0,35 / 4 -8 Kuopio,Finland, e-mail: jukka.juutilainen@uku.fi (RR/J.J.)

cw > (currentaddress/S.L.); Dept. of Environmental Sciences, Univ. of Kuopio, P.O. Box 1627, FIN-70211 chronic

above nn GSM phone nn intermittent 0 female 200 whole body

STUK Radiation RAY INDUCED 156(6) Telephones/9 days/weeks (CBA/S) (tumori-genesis)

Kumlin, T.; (PW)

and Nuclear TUMORIGENESIS IN MICE 00 (NMT900) for 78 weeks

Lahtinen, T.;

Safety Authority; network

Lang, S.;

Nokia Res.

Puranen, L.;

Center;

Juutilainen, J.









Pilot experiments on

Physiol

temperature cycling in rats clearly

70 Heinmets, F. Heinmets F nn nn USA 1982 Chem Phys 2.06 2.06 none nn nn nn nn pulsed nn 50 - 200 nn cw = pw nn nn nn 1 day nn nn 0 rat nn nn nn thermo-regulatory

exposed repetitively to above

14 (6)

radiofrequency radiation (RFR)









described in Heinmets et al.

(Temperature Cycling in Rats

Technology Inc.; A NEW METHOD OF SAR living: living:

Heinmets, F.; Physiol Exposed Repetitively to RF

Trinity Univ.; DETERMINATION IN 2,8 15,4; 15,8 -16.3; Radiation.

Frei, M. R.; Chem Phys 5,6

Stadium Dr., USA Radiation Physics Branch,Radiation Science Div., USAF Sch. of Aerospace Medicine, Brooks AFB, TX 78235 (W.D.H.)

16 (F.H., J.R.J.); TrinityUniv., Dept. of Biology, 715USAF Sch. of San Antonio, TX 78284 (M.R.F.); 1984

71 Heinmets, F. ANIMALS EXPOSED TO (CW, none 500 500 2 2 pulsed nn 60 60 16,8; cw = pw above nn nn nn acute intermittent 0 rat nn nn whole body thermo-regulatory

Jauchem, J. R.; Med NMR (CW) SAM-TR-82-48, School of

Aerospace MW/RF RADIATION PW) dead: dead: Aerospace Medicine, Brooks

Hurt, W. D. 16(1)

Medicine (MW/RFR) 15,1-15,4 14,8-15,6

AFB, Texas, 1982; BENER

Abstract No. 0935)









Inst. of

Pharmacolo

gy and

Huber, R.; Toxicology,

Treyer, V.; Univ. of

Borbely, A. A.;

Univ. of Zurich; Zurich, EMF, SUCH AS THOSE

Schuderer, J.; Winterhurers

Univ. Hosp.; FROM MOBILE PHONES,

Gottselig, J. M.; head between two plates part:

Foundation for trasse 190, ALTER REGIONAL J Sleep Res GSM- human

72 Huber, R. Landolt, H. P.; Switzerland 2002 0.9 0.9 none nn GSM-like nn GSM-like nn nn 1 /1 nn close to nn with respect to two planar nn 30 minutes acute continuous 1 male 2 x 16 head; nervous

Res. on Inform. CH-8057 CEREBRAL BLOOD FLOW 11(4) like (volunteers)

Werth, E.; antennas left side

Technol. in Soc. Zurich, AND SLEEP AND WAKING

Berthold, T.; Switzerland,

(IT'IS) EEG

Kuster, N.; e-mail:

Buck, A.; acherman@

Achermann, P. pharma.uniz

h.ch

(RR/P.A.,

R.H.,









Huber, R.;

EXPOSURE TO PULSE-

Treyer, V.;

MODULATED RATIO

Schuderer, J.;

FREQUENCY Eur J pulsed part:

Berthold, T.;

73 Huber, R. Switzerland

Univ. of Zurich; Inst. of Pharmacology and Toxicology, Univ. of Zurich, Winterhurerstrasse 190, CH-8057 Zurich,

2005 ELECTROMAGNETIC Neurosci. 21 0.9 0.9 none nn nn nn nn base-station-like, nn nn nn 1 /1 nn close to nn nn nn nn 30 min acute continuous 1 human male 12 head nervous

Buck, A.;

FIELDS AFFECTS (4) handset-like (unilateral)

Kuster, N.;

REGIONAL CEREBRAL

Landolt, H. P.;

BLOOD FLOW.

Achermann, P.







Forschungsgemeinschaft Funk e.V. 2f7970c4-fa63-48a5-bb8d-bba54b3501af.xlsstudies

Seite 28 von 100

Werner Alsbach / Jürgen Zschernitz / Margarita Simeonova Ausdruck vom 11/16/2011

Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The authors briefly No significant differences in heart rate were

review studies on detected between

the effects of the embryos exposed to CW and SARs of 15 and

microwave (MW) 30 mW/g, or to pulsed MW. These results suggest

radiation on the that the heart rate of the in vivo

heart and heart quail embryo is not greatly affected

rate. In order to by

clarify those short acute exposures to CW or

sometimes pulsed 2450 MHz radiation and

heart rate fix nn nn EXP CVS in vivo conflicting reports, organ function no -/- nn that the nn nn nn ´- (heart rate) ´- (heart rate)

the in vivo effect of window effect or optimum

2450 MHz MW exposure intensities observed in

radiation on the calcium efflux in

heart rate of 8-13 the brain of chicken is not operative

day old Japanese in this system. The importance of

quail embryos was accurate dosimetry is stressed.

studied. Two MW

sources were

used: one for

Microwave energy Maximum temperatures at 0.5 mm were Thus, microwave pulsing achieves nn nn nn ↑++ (temperature ↑+ (temperature amplification (cw)

has been proposed significantly lower at 63.2 +/- 5.89 degrees C for a lower endocardial temperature increase, 0.5 mm increase, 0.5 mm

as a possible the 1-sec pulse compared with 83.5 +/- 7.31 and results in a more uniform depth) depth)

technique to create degrees C for the continuous-energy delivery. Pulse temperature gradient. These

large configurations 3 sec on-3 sec off and 5 sec on-5 sec techniques may prevent the ↑+ (temperature ↑+ (temperature

tissue CVS; physical myocardial lesions. morphological and off also resulted in a significantly lower surface excessive increase, 2.0, 3.5 increase, 2.0, 3.5 mm

tissue temperature at 0.5, 2.0 and Achieving a temperature than continuous-energy delivery. endocardial damage that may mm depth) depth)

yes (myocardial) yes EXP PHY; model pathological -/- yes nn

3.5 mm depth uniform myocardial However, temperature at the 2.0-mm and 3.5-mm result in an increased risk of

TMP system changes

temperature depth created by the pulsing delivery were thrombus formation and

gradient similar to those achieved during continuous- embolization.

during microwave energy delivery.

ablation may

prevent excessive

endocardial

The authors Nocturnal excretion of aMT6s on a per animal basis

examined the showed no significant differences between The authors concluded that

effects of chronic, long-term exposure to 50-Hz

exposed and sham

long-term 50-Hz magnetic fields and RF radiation of

exposed groups in either experimental series,

EMFs and the type associated with cellular

although there was a significant increase in

900-MHz phones does not alter urinary

aMT6s excretion in all 3 RF groups (sham,

radiofrequency excretion of aMT6s,

continuous, and pulsed RF) compared to cage

(RF) radiation the primary melatonin metabolite,

controls and the 50-Hz groups (p purpose of the and 20%, respectively) compared to the cage sham exposure/ ↑++ (nonneoplastic

feed and water consumption; nn nn nn EXP TUM study was to no -/-

cancer nn The nn benign tumors); ´- changes- dilated

vitro controls. RF radiation did not increase significantly shelf control changes- acinar cell

hematological evaluate the role of results, therefore, do not provide (nonneoplastic glands in the

the incidence of any neoplastic lesion but causes hypertrophy in the

evaluations; histopathological low-level evidence for cancer promotion by changes stomach, dilatation of

some significant nonneoplastic changes (CW led pancreas; decreased

analyses of all lesions radiofrequency RF the uterus

to dilated glands in the stomach (p=0.022) and incidence of

(RF) radiation of radiation emitted by cell phones. and decreased

dilatation of the uterus hyperplasia in the

the type incidence of liver

(p=0.038), and decreased the incidence of liver cervical lymph)

emitted by cellular inflammation)

inflammation (p=0.017) relative to the sham-

telephones as a exposed group; PW increased

tumor promoter. the incidence of acinar cell hypertrophy in the

Ionizing radiation pancreas (p=0.022) and temperature regulation of of

no observable effect on decreased the incidence

rats in terms of heat dissipation efficiency.

are

agnetic energy into biological systems while the systems nn maintained at physiologically acceptable temperatures. Experiments were carried out at various power densities (50-200-/-

temperature regulation nn nn EXP TMP in vivo thermoregulation no mW/cm2) using continuous wave (CW) and pulsed radiation while the carrier frequency was maintained at 2.06 GHz. It was observed that single-day RFR exposures at power levels used in this series produced no observable effect on temperature regulation of rats in terms of heat dissipation efficiency.

nn nn nn nn nn ´- (thermoregulation) ´- (thermoregulation)





The authors There was relatively close

proposed a new agreement between the SARs determined by the 2

method for techniques. SARs obtained

determining SARs for CW and pulsed RF radiation exposures did not

in laboratory differ significantly from

animals each other. The authors concluded that the

exposed to proposed method is a simple, less

microwave and time-consuming procedure for

colonic;

radiofrequency determining SARs in live animals.

SAR by temperature (subcutan.; tympanic;

yes yes EXP TMP in vivo (RF) radiation. thermoregulation no -/- nn The method nn nn SAR value SAR value

colonic; tympanic membrane) subcutaneo

The method was is very reliable and can be used in

us

based on a acute, repetitive, and chronic

temperature microwave and RF radiation

cycling procedure, exposure experiments.

described in detail

in Heinmets

et al. (Temperature

Cycling in Rats

Exposed

The authors Exposure to the GSM-like signal in the second The authors concluded that nn sham-exposure nn ´- ↑+ (EEG power in the increase (pw)

conducted two experiment enhanced EEG power in the alpha exposure to a GSM-like RF field alpha band and in the

experiments band and in the spindle frequency range during alters awake rCBF and brain spindle frequency

examining the stage 2 sleep. The effect showed an increasing electrical activity during sleep. range and spindle

effects of cell trend in the course of the night, and enhancement of The health consequences of these amplitude)

regional cerebral blood flow by phone-like power in the spindle frequency range by GSM-like effects are unknown. The authors

positron emission tomography radiofrequency ´- (duration and

RF exposure paralleled a general increasing trend of suggested that future studies

(PET) scans (only pw) (RF) fields on number of sleep

in vivo changes of the spindle frequency activity though the night, being should not focus only on

nn nn nn EXP CNS regional cerebral -/- yes nn spindles; REM sleep

probands neurological system largest in the fourth and fifth non-REM sleep possible harmful effects of

blood flow episodes. Spindle amplitude was significantly pulse-modulated RF field latency, duration of

sleep EEG activity, EOG, EMG (pw (rCBF) and sleep the non-REM/REM

increased in the exposed condition, by 5.4 +/- 1.4% exposure, but examine its

and cw) EEG activity in sleep cycles)

relative to the unmodulated 900-Hz signal exposure potential as a noninvasive

human volunteers. and by 2.9 +/- 1.5% relative to sham-exposed method for modifying brain

In the first controls (p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=







1. (pw) and

2.(cw and

0,915

0,8 pw)

for 2,5;

(for 0,01; experiment:

Iurinskaia, M. M.; REACTION OF THE BRAIN experi 3;

experim 0,05; cage, from an open end of a 5minutes

Iurinskaia, M. Kuznetsov, V. I.; Acad. of RECEPTOR SYSTEM TO Biofizika ments 5; pulsed close to / rat organ

74 Physics,

Inst. of Biological Russia Russian Acad. of Sciences, Pushchino, Moscow Region, 142292, Russia

1996 ents none 2.5 nn nn nn nn cw = pw nn nn acute continuous 0 male nn whole body

M. Galeev, A. L.; Sciences THE EFFECT OF LOW 41(4) with 7; (rectangular) 0,1; above waveguide (Wistar, 150-200 g) (nervous)

with 3H- 3.

Kolomytkin, O. V. INTENSITY MW 3H- 16; 1

muscim experiement:

glutam 30

ol) 1 - 60

ate)

minutes (nur

pw)









COMPARISON OF THE

Jamakosmanovic,

EFFECT OF CW AND

A.;

PULSED 2450-MHz MW 0,172 / 0,179 rat

Jamakosmano Jevric, A.; Univ. of Period Biol 8,26/ waveguide system daily organ

75 Yugoslavia

Dr. Alexander Sabovljev Inst. of Physiology and Biochemistry, Faculty of Medicine, Univ. ofSarajevo, Mose Pijade 6, 71000 Sarajevo, Yugoslavia

1983 IRRADIATION ON THE 2.45 2.45 none 100 100 2 2 pulsed / 2.500 J/kg J/kg cw = pw above nn nn temporary intermittent 0 (albino, nn >8 whole body

vic, A. Nakas, M.; Sarajevo 85(2) for 28 days (nervous)

LEVEL OF ATP, ADP AND body weight body weight 7 day old)

Drecun, M.; ch

AMP IN DEVELOPING RAT

Shore, M. L.

BRAIN.









Utsunomiya

Univ.; Nippon

oscillator (Wiltron, model

Veterinary monkey

Kamimura, Y.; EFFECT OF 2.45 GHz MW 610D with 6213), a TWT

and Animal Sci. IEICE Trans (cynomolgus,

Saito, K.; IRRADIATION ON MONKEY 5,3-7.,8; amplifier (Hughes, model

Y.K.); Nippon Veterinaryand Animal Sci. Univ., Musashino-shi, 180, Japan (K.S.); Nippon Medical Sch., Tokyo, 113, Japan(T.S.); Faculty of Engineering, Kanazawa Inst. of Technology, Ishikawa-ken, 921, Japan (Y.A.)

76 Kamimura, Y. Univ.; Japan 1994 Commun 2.45 2.45 none nn nn nn nn pulsed nn 15,9 - 43,0 cw = pw above nn near-field 4 hours acute continuous 0 Macaca nn 5 whole body sensoric

Saiga, T.; EYES 2.6 1177H) and an applicator (HP-

Nippon Medical E77B(6) fascicularis, adult,

Amemiya, Y. (LETTER) S281A),

Sch.; unanesthetized)

near-field

Kanazawa Inst.

of Technology









THE ACTION OF MW

Sechenov First 13;

RADIATION ON POTASSIUM organ

Khitrov, Iu. A.; Moscow Inst. of Radiobiologiia 17; nn 100 - 5000 clearly nn organ part:

77 Khitrov, Iu. A. Russia

Sechenov First Moscow Inst. of Medicine, Moscow, Russia

1990 ION TRANSPORT AND 2.45 2.45 none 13 nn nn pulsed nn cw = pw nn near-field nn nn nn 0 nn nn (digestive:

Kakushkina, M. L. Medicine, 30(2) 21; above (liver of rat) liver

OXYGEN CONSUMPTION IN liver)

Moscow, Russia 25

THE PERFUSED RAT LIVER









Komatsubara Y,

Effect of high-frequency

Hirose H, 5;

electromagnetic fields with a

Sakurai T, 10;

Komatsubara Hirosaki wide range of SARs on Mutat Res. cw ≤ pw cell cell:

artment of Radiological Technology, School of Health Sciences, Faculty of Medicine, Hirosaki University, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.

78 Koyama S, Japan 2005 2.45 2.45 none nn nn nn nn pulsed nn nn 20; 100 / 900 above nn nn nn 2 hours acute continuous 0 nn nn cell

Y, University chromosomal aberrations in Sep 29 (average) (mouse) mouse m5S

Suzuki Y, 50;

murine m5S cells.

Taki M, 100

Miyakoshi J.









DELAYED EFFECTS OF

MODULATED AND NON- Radiats Biol GSS-12M generator 5 rat

Konovalov, V. Konovalov, V. F.; Russian Acad. 4;

79 Serikov,

Konovalov, V. F.;Russia I. S.Inst. of Cell Biophysics, EMF ONAcad. of Sciences, 142292 Pushchino, Moscow Region, 4

2001 MODULATED Russian Radioecol 0.88 0.88 none 142292Russia, e-mail: admin@mars.ibioc.serpukhov.su nn

nn nn pulsed 1 1 nn cw = pw above nn described by Tygranyan and nn minutes/day acute intermittent 0 (Wistar, initial body female 40 whole body sensoric

F. Serikov, I. S. of Sciences 16

EPILEPTIFORM ACTIVITY IN 41(2) Mashkin for 5 days weight 180 to 200 g)

RATS









Kubinyi G, Natl. "(Frederic Effect of CW and amplitude- standard horn antenna

Thuroczy G, Joliot-Curie"( modulated 2.45 GHz MW powered by an

Bioelectro- HP 8616 microwave 100 mouse

Bakos J, Res. Inst. for radiation on the liver and brain pulsed cw = pw (PFD); cell

Hungary

nst. for Radiobiology and Radiohygiene, Budapest, Hungary; Natl. "(Frederic Joliot-Curie"( Res. Inst. for Radiobiology and Radiohygiene, Budapest, H-1775 POB 101, Hungary (RR/G.K.) 50

80 Kubinyi G, 1996 magnetics 2.45 2.45 none 50 nn nn nn 3 4.23 8.46 above nn nn minutes/day, chronic intermittent 0 (CFLP, pregnant female 948 whole body

Boloni E, Radiobiology aminoacyl-transfer RNA (square) cw effect of low- changes of the frequency 16 Hz) decrease (pw)

nn nn nn EXP NES intensity -/- yes

density vitro neurological system 2. experiment (cw and pw): Neither CW nor

microwaves on the modulated regimens produced a statistically ↑+ (glutamate binding, increase (pw)

2. experiment: role of modulation, state of significant change in 3H-muscimol binding, modulation frequency

modulation frequencies were varied glutamatergic and except for 16-Hz modulation which decreased its 16 Hz)

GABA-ergic binding to 70 +/- 5%. Maximum increases in the

3. experiment: exposure duration systems was 3H-glutamate binding (to 200-220%) also occurred

was varied from 1-60 min studied at 16-Hz modulation.

in male Wistar rats

(150-200 g body 3. experiment (nur pw): Maximum decrease in the

weight). Animals

Seven day old 3H-muscimol binding (toirradiated controls, CW

When compared to sham 45-50%) occurred after nn nn sham-exposure nn ↑+ (AMP-level) ´- (AMP-level) increase (cw)

albino rats were repetitive irradiation decreased average brain ADP (´-) ↓+ (ADP-level) ↓+ (ADP-level)

exposed daily for levels by 48% and increased AMP levels by 23%, ´- (ATP-level) ´- (ATP-level)

28 days to 2450 but had no significant effect on ATP levels. PW

ATP, ADP and AMP levels MHz

ENA; in vivo -> repetitive irradiation decreased ADP levels by 55%

(using the Boehringer enzymatic nn nn nn EXP continuous wave cell function -/- yes nn

NES vitro but had no significant effect on AMP or ATP

method)

(CW) or pulsed levels.

wave (PW)

microwave

irradiation to

evaluate effects

The ocular Slight conjunctivitis in 1 monkey was the only The authors concluded that no

of irradiation with abnormality seen. No corneal epithelial microwave irradiation-associated

2.45-GHz abnormalities, cataracts, or vitreous humor, retinal, eye bnormalities were observed

The authors

microwaves were orcorneal endothelial anomalies were detected. even though greater power

suggested that

studied in densities were used, compared to

halothane

monkeys. The by Kues et al. The most significant

anesthetic may have

abnormities of anterior parts purpose of the differences between the studies

EYE; changes of the compromised the

of the eyes, the vitreous humor, and nn nn nn EXP in vivo study was to no -/- was the use of anesthetic nn nn nn ´- (ocular effects) ´- (ocular effects)

SEN neurological system patterns of circulation

retina attempt to replicate (halothane) by Kues et al., and the

in the eye and

the findings use of daily or weekly exposures

altered metabolism,

of Kues et al. rather than the single acute

contributing to a MW

(Bioelectromagnetic exposure used in these

effect.

s 6:177-188, 1985; experiments. The authors

BENER Abstract suggested that halothane

No. anesthetic may have compromised

This research was Microwaves applied at temperatures around

undertaken in 20 C had no effect on potassium efflux and

order to determine exposure enhanced oxygen consumption to an

possible nonthermal extent dependent on microwave heating. This effect

effects of was completely reversible and well reproducible by

microwave equivalent conventional heating

exposure. It was membrane The data indicated an absence of ´- (potassium efflux); ´- (potassium efflux);

potassium ion efflux fix ext medium yes EXP VDS in vitro shown first that function; no -/- nn any nonthermal microwave nn nn nn ↑+(potassium efflux ↑+(potassium efflux at

increasing the organ function influence. at thermal levels) thermal levels)

ambient

temperature from

25-30 to 40 C, as

well as decreasing

it from 15 to

3 C enhanced

To investigate the High frequency EMF exposures do not induce

induction of chromosomal aberrations in m5S cells.

chromosomal Furthermore, there was no difference between

aberrations in exposures to CW and PW HFEMFs.

mouse m5S cells

after exposure to

induction of chromosomal high-frequency ´- (chromosomal ´- (chromosomal ´- (chromosomal

aberrations: structural, chromatid- nn nn nn EXP GEN in vitro electromagnetic genotoxicity no -/- nn nn nn sham

abberations) abberations) abberations)

type and chromosome-type changes fields (HFEMFs) at

2.45GHz, cells

were exposed for

2h at average

specific absorption

rates (SARs) of 5,

10, 20, 50

The authors and The results were recorded as the percentage of nn nn sham-exposure epileptiform epileptiform activity: epileptiform activity: decrease (pw)

examined the animals showing audiogenic seizures. The 4th activity:

effects exerted by (control) group did not show any changes in the ´- ´- ( after 2 months) ↓++( one day after increase (pw)

expression of audiogenic seizures electromagnetic initial seizure frequency value of 100% during the ↓+ (after 6 months) exposure until 2

radiation (EMR) whole follow-up period. In the 1st group, percentage of ↓++ (with 18 months) months after decrease (cw)

percentage of survivors on the expression epileptiform activity was at the initial 100% level for survivors: (↑+) (after 18 months) exposure)

(determined 12, 18, 24, and 26 mo of audiogenic 2 mo, then declined and remained at 80% for the ↓(+) ↑+ (after 2 months) attenuation (cw)

seizures in rats. abdominal tumors percentage of ↓+ (after 18 months;

post-exposure) next 4 mo, which was followed by further decline to

Changes over their were observed in survivors: modulation frequency contrary effects

changes of the 20% (a significant decrease, p molecular previously to occur at

activity (p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=

1) weekly 4

hr to 5-30

mW/cm2

(repeated for

1-56 weeks)



Kues, H. A.; 2) a series of

Hirst, L. W.; 0,26 per 1 single

Johns Hopkins EFFECTS OF 2.45-GHz MW Bioelectro- 0,26; below / 10 cm from acute; monkey

Lutty, G. A.; mW/cm2; 10-30 part: organ

81 Kues, H. A. Univ Applied USA

Johns Hopkins Univ Applied Physics Lab, Johns Hopkins Road, Laurel, MD 20707

1985 ON PRIMATE CORNEAL magnetics 2.45 2.45 none 100 100 10 10 pulsed nn 5 - 30 2.6 cw ≥ pw close to / nn nn the ocular mW/cm2 temporary; intermittent 0 (cynomolgus, nn 5 (?)

D'Anna, S. A.; eye (sensoric)

Physics Lab ENDOTHELIUM 6(2) / above surface exposures of chronic Macaca fascicularis)

Dunkelberger, G. 5,3-7,8

R. 4 hr

separated by

one or more

weeks;



3) 4

consecutive

daily 4 hr









whole body



waveguide system, (more SAR on

ACUTE LOW-LEVEL MW

or Narda-644 standard gain head region

Lai, H.; Univ. EXPOSURE AND CENTRAL Bioelectro- 0,6 (cylindrical waveguide) horn mounted at the tapered rat (cylindrical histological cut

82 Lai, H. Horita, A.; Washington USA

Dept. of Pharmacology, SJ-30, Univ. ofCHOLINERGIC ACTIVITY:

1988 Washington Sch. of Medicine, Seattle, WA 981952.45 H.L.,A.H.); Psychiatry & Behavioral Sciences, Univ. of Washington Sch. of Medicine, Seattle, WA (A.H.);Center for Bioengineering, Univ. of Washingtoncw = pw Medicine, Seattle, WA (H.L., A.W.G.)

magnetics (RR/ 2.45 none 500 500 2 2 pulsed nn nn Sch. of above nn nn 45 minutes acute continuous 0 male nn

1,0 (standard gain horn) roof (Sprague-Dawley) waveguide (nervous)

Guy, A. W. Sch. Medicine STUDIES ON IRRADIATION 9(4) over a plastic cage housing system) or tail

PARAMETERS the rat region

(standard gain

horn)









ACUTE LOW-INTENSITY MW 0,6 cylindrical waveguide system

EXPOSURE INCREASES Bioelectro- 1.2 as described by Guy et al

Lai, H.; Univ. of 1; rat cell

83 Lai, H. Dept. of Pharmacology, SJ-30, Univ. ofDNA SINGLE-STRAND 98195 (RR/H.L.)

USA Washington, Seattle, WA

1995 magnetics 2.45 2.45 none 500 500 2 2 pulsed nn cw = pw above nn (Radio Sci 14(6S):63-74, nn 2 hours acute continuous 0 male nn whole body

Singh, N. P. Washington 2 (Sprague-Dawley) (nervous)

BREAKS IN RAT BRAIN 16(3) local SARs in 8 brain 1979;

CELLS regions ranged from 0,5 - 2 BENER Abstract No. B-6559)









SINGLE- AND DOUBLE- cylindrical waveguide system

STRAND DNA BREAKS IN developed by Guy et al.

Lai, H. ; Univ. of RAT BRAIN CELLS AFTER Int J Radiat (Radio Science 14:63-74, rat cell

84 of Washington,Seattle, WA 98195 (RR/H.L., N.P.S.)

Bioelectromagnetics Res. Lab., Center for Bioengineering, Box 357962, Univ. USA

Lai, H. 1996 2.45 2.45 none 500 500 2 2 pulsed nn 2 2 1.2 cw = pw above nn nn 2 hours acute continuous 0 male nn whole body

Singh, N. P. Washington ACUTE EXPOSURE TO RF Biol 69(4) 1979; (Sprague-Dawley) (nervous)

EM BENER Abstract No. B-6559),

RADIATION. with a single RF power source









PULSE-MODULATED AND

Univ. of Texas CW MW RADIATION

Physiol rat whole organism

85 Lebovitz, R. M. Lebovitz, R.of Physiology, Univ. of Texas Health Science Center, Dallas, TX 75235

Dept. M. USA

Health Science 1983 YIELD EQUIVALENT 1.3 1.3 none 600 600 1 1 pulsed nn nn 5.8 6.7 cw either PW or CW MW. MW), and striatal choline uptake

choline uptake in striatum, frontal nn nn nn EXP NES sodium-dependent pathological -/- yes nn waveguide and waveguide and decrease (pw)

vitro depends on the irradiation system

cortex, hippocampus, and high-affinity choline changes standard gain horn) standard gain horn)

When rats were exposed to either PW or CW MW used (decreased with PW or CW

hypothalamus) uptake. The brain in the miniature anechoic chamber, striatal and MW in the anaechoic chamber but

areas studied frontal cortical choline uptake were both not the waveguide). Changes of ´- (high affinity ´- (high affinity choline

were the striatum, decreased. Choline uptake in the hippocampus this magnitude, which the authors choline uptake, uptake, striatal

frontal cortex, was decreased after exposure to PW MW in the would expect to have significant striatal, waveguide) waveguide)

hippocampus, and chamber, but was not modified with exposure to CW behavioral consequences, can decrease (pw)

hypothalamus -- MW. Hypothalamic choline uptake was not apparently depend on parameters ´- (high affinity ↓+ (high affinity

areas affected by exposure to either PW or CW MW in the of the exposure conditions and choline uptake, choline uptake,

involved of

Inductionin DNA chamber. to PW microwaves did not induce any

Exposure The magnitude of the changes in choline localauthors concluded that acute

The dosimetry. nn sham-exposure nn striatal, standard gain striatal, standard gain

↑+ (DNA-damage, ´- (DNA-damage, increase (cw)

damage in brain DNA damage in rats examined immediately after microwave exposure increases immediatly after immediatly after

cells by acute low- exposure ended. Significant increases (p example, data given in figures for whole brain cells breakage could reflect an increase

electrophoresis nn nn nn EXP technique. Male genotoxicity -/- yes nn hours after exposure increase (pw)

NES vitro exposed to PW microwaves indicated an increase in in the breakage rate or an

technique and fluorescence Sprague-Dawley ended; 1.2 W/kg)

mean DNA migration from approximately 150 impairment of DNA repair

microscopy ) rats were exposed (microns) in sham-exposed controls to 190 at 0.6 processes. No simple explanation

or sham exposed to W/kg and 240 at 1.2 W/kg. Following exposure to exists for the different responses of

continuous (CW) CW microwave radiation, significant increases in brain cell DNA to PW and CW

or pulsed wave DNA damage were seen in rats examined both microwaves. This finding

(PW) circularly immediately and 4 hr after exposure. supports the view that biological

polarized 2,450- responses to microwaves

MHz depend on the parameters of the

microwaves for 2

The authors Both pulsed and CW RF radiation significantly The authors concluded that acute

examined the increased the length of DNA migration single- exposure to RF radiation at an

effects of in vivo strand breaks (p Male Sprague- sham and PW exposure (chi square = 921.5, 13 limit recommended by the Institute breakage of covalent bonding double DNA breaks; double DNA breaks;

nn nn nn EXP Dawley rats were genotoxicity no -/- nn of Electrical and Electronics in the DNA molecule. These sham exposure ´-

breaks (microgel electrophorese) NES vitro degrees of freedom, p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









Univ. of

Sheffield

Medical Sch.; EFFECT OF 900 MHz EMF TEM cells powered by a

Lim, H. B.;

Inst.of High ON NONTHERMAL 3; 0,4; function generator, a cell cell culture:

Cook, G. G.; Radiat Res below / 20 minutes; 2 male; 1 cell culture

R/L.A.C.); Electronics and Electromagnetics Div.,Inst. of High Performance Computing,UK

87 Lim, H. B. Performance (H.B.L.); Dept. of Electronic & ElectricalEngineering, Univ. of Sheffield, UK (G.G.C.); Dept. of Medical Physics and Clinical Engineering,Royal Hallamshire Hosp., Sheffield, UK (A.T.B.)

Singapore 2005 INDUCTION OF HEAT- 0.9 0.9 none nn nn nn nn GSM-like 14; nn 2,0; 0.4 cw ≥ pw nn signal generator, and a nn acute continuous 1 (human leukocytes, 3 human

Barker, A. T.; 163(1) close to 1 hr; 4 hr female (immune)

Computing; SHOCK PROTEINS IN 25 3,6 3 healthy volunteers) leukocyte

Coulton, L. A. power amplifier

Royal HUMAN LEUKOCYTES

Hallamshire

Hosp.









FURTHER EXPERIMENTS

Lindauer, G. A.; IEEE Trans

SEEKING EVIDENCE OF

Liu, L. M.; Washington Microw beetle cell

88 Lindauer, G. A. WA

Washington Univ., St. Louis,USA 1974 NONTHERMAL BIOLOGICAL nn nn nn nn nn nn nn pulsed nn 8.6 nn cw = pw above nn nn nn nn nn 0 nn nn nn

Skewes, G. W.; Univ. Theory Tech (pupae) (pupae)

EFFECTS OF MW

Rosenbaum, F. J. MTT-22(8)

RADIATION









MITOGEN

RESPONSIVENESS AFTER

Univ. of EXPOSURE OF INFLUENZA waveguide system

Roberts, N. J., Jr.;

Rochester VIRUS-INFECTED HUMAN Radiat Res 16; 4 as described by Lu et al. cell part: cell culture

89 Depts. USA 1987

Lu, S-T. of Medicine, Radiation Biology, and Biophysics, Univ. of Rochester School of Medicine,Rochester, NY 14642

Michaelson, S. M.; 2.45 2.45 none 16 nn nn pulsed nn nn

mW/ml cw = pw above nn (J Microwave Power nn 2 hours acute nn 1 nn nn

School of MONONUCLEAR 110(3) 60 (human, leukocytes) blood (immune)

Lu, S-T.

Medicine LEUKOCYTES TO CW OR 18:121,1983)

PULSE-MODULATED RF

RADIATION









ERC

Lu, S-T.; ABNORMAL

BioServices 4,75 W/kg per W

Brown, D. O.; CARDIOVASCULAR IEEE Trans 1) 2 / 400; transmitted to the brain; L-band (WR650) waveguide rat

Corp.; 0,5; 1) 1;

rg, MD 20879 Lu, S-T. D.O.B., C.E.J., S.P.M.); Dept. ofMicrowave Res., Div. of Neuropsychiatry, Walter Reed Army Inst. ofINDUCED BYGlen Annex,Washington, DC 20307 (E.C.E.)

90 (S-T.L., Johnson, C. E.; USA 1992 RESPONSES Res., Forest Biomed Eng 1.25 1.25 none 0.5 1 pulsed 2) 6,4 / nn cw = pw above nn near-field nn nn nn 0 (Sprague-Dawley, male 36 whole body cardio-vascular

Walter Reed 16 2) 10 17,15 W/kg per W exposure system

Mathur, S. P.; Elson, LOCALIZED HIGH POWER 39(5) 400 10-12 wk old)

Army Inst. of transmitted to the neck

E. C. MW EXPOSURE.

Res.









pseudorandom

CYTOGENETIC EFFECTS (GSM during

Maes, A.; Vito, Bioelectro- below / TEM cell cell part:

OF 900 MHz (GSM) conversation); 2; 8; 0,4; 2,0; cell culture

91 Vito, Environmental Toxicology, Boeretang 200, B-2400 Mol, Belgium, e-mail: annemie.maes@vito.be(RR/A.M., M.C., L.V.)

Maes, A. Collier, M.; Environmental Belgium 2001 magnetics 0.9 0.9 none nn nn nn nn nn cw = pw close to / nn nn 2 hours acute continuous 1 (human nn 8 blood

MICROWAVES ON HUMAN dummy burst 15; 25; 50 3,5; 5,5; 10 and CDMA generator (immune)

Verschaeve, L. Toxicology 22(2) above lymphocytes) (lymphocytes)

LYMPHOCYTES (GSM in stand

by)









Mahrour, N.; IN VITRO INCREASE OF THE

Pologea-Moraru, R.; FLUID-PHASE

Moisescu, M. G.; ENDOCYTOSIS INDUCED Biochim cell

Institut Gustave- exceeding

Transfert de France

ctorologie etMahrour, N. Genes, UMR 8121 CNRS, Institut Gustave-Roussy, 39 rueCamille Desmoulins, 94805BY PULSED RFFrance, e-mail: luismir@igr.fr (L.M.M.) 0.9

92 Orlowski, S.; 2005 Villejuif Cedex, EMF: Biophys Acta 0.9 none 217 217 580 580 GSM-like nn nn 1,3 - 2,6 cw = pw close to nn nn nn nn nn nn (fluid-phase endo- nn nn cell cell

Roussy 10 minutes

Leveque, P.; IMPORTANCE OF 1668(1) cytosis)

Mir, L. M. THE ELECTRIC FIELD

COMPONENT









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The authors Heat stress (42 C) caused a time-dependent The authors considered these

examined the induction of HSP 70 and HSP 27. In general, responses random fluctuation, a

potential of low responses to heat stress consequence of the small number

intensity cell phone were more pronounced in monocytes than in of experimental repeats. Other

radiofrequency lymphocytes. No significant differences between groups have reported much higher

(RF) emissions to RF and the sham exposure values. There were a increases in expressions of HSP

induce expression few experiments in which RF exposed cells showed 27 and HSP 70 in human

of heat shock modest increases compared to the conventionally endothelial cells (Leszczynski et

expression of heat shock proteins proteins molecular heated control. al., Differentiation 70:120-129, sham-exposure/ ↑+ / ↑++ ↑+ (induction of

yes suspension yes EXP CEF in vitro (HSPs) in human no -/- nn 2002; BENER Abstract No. 23710) nn ↑+ (induction of HSP)

(HSPs) in human leukocyte cultures biosynthesis shelf control (induction of HSP) HSP)

leukocyte cultures and in human amnion epithelial

as a test of the cells (Kwee et al., Electro

hypothesis that cell Magnetobiol 20:141-152, 2001;

phone radiation BENER Abstract No. 21875),

can induce a respectively.

nonthermal stress One possible explanation for the

response (HSP discrepancy, the authors pointed

induction) in out, is that the cells examined by

human peripheral

Carpenter and none Leszczynski et al. and Kwee et al.

Livstone's (see

abstr. A26834,

1971) experiments

on beetle

pupae are

repeated and

extended. In the

experiments ↑+ (abnormal ↑+ (abnormal

abnormal development nn nn nn EXP TER in vivo conducted, teratogenity no -/- nn nn nn nn nn

development) development)

increased

incidence of

abnormal

development

occurred due to

exposure to

microwave

energy, both CW

and pulsed. This

While there are Exposure of leukocytes to influenza virus and/or

many studies of RFR produced no significant changes in cell viability

the effects of for up to 1 week after exposure. No significant

radiofrequency differences were found between the response of

radiation uninfected RFR-exposed, infected RFR-exposed,

(RFR) on normal and sham-exposed leukocytes to optimal or sub-

"healthy" human optimal concentrations of phytohemagglutinin. The authors conclude that

mononuclear Results were the same for both CW and pulse- influenza virus-infected human

leukocyte viability leukocytes (MNL), cell vitality, cell modulated RFR. MNL do not show significant

by use of cell counts; nn nn nn EXP IMM in vitro no data is no -/- nn nn sham exposure ´- (cell viability) ´- (cell viability) ´- (cell viability)

division effects resulting from subsequent

DNA synthesis available regarding exposure to RFR under the

effects of RFR on reported conditions.

MNL already

challenged by a

commonly

encountered

pathogenic agent,

such as a virus.

This study

Soviet clinicians Mean baseline heart rates of animals in each group

have described a were not statistically different from each other. Underperfusion hypothesis of

syndrome which Respiration rate and mean arterial pressure were Johnson for heart rate

they have called not altered in any group. Changes in heart rate and changes: Total peripheral

"microwave pulse pressure were observed in rats exposed resistance would have to

sickness" which to either 16-Hz PW microwaves or 6.4-W CW The authors suggested that, due to increase to maintain a

consists of such microwaves, but not to lower average power these cardiac deficits and constant mean arterial

symptoms as microwaves. Depression of pulse pressure, abnormal vascular response, the pressure in the presence of

heart rate, mean CVS; bradycardia, tachycardia, or bradycardia were observed microwave subnormal cardiac output. ↓+ (heart rate, blood ↓+ (heart rate, blood

arterial pressure, pulse pressure, yes body nn EXP RES; in vivo tachycardia, physiology no -/- nn sham exposure ´-

when microwaves produced whole-body exposure conditions precipitating Increased peripheral preassure) preassure)

respiration rate, body temperature TMP hypertension, hyperthermia. these physiological deficits should resistance during microwave-

hypotension and be induced hyperthermia was

changes in the T- investigated. contrary to the anticipated

wave. The thermal or hyperthermic

collective response of animals,

symptoms of such constituting an abnormal

a "vegetative physiological djustment.

vascular

syndrome" were

The authors' RF exposure alone did not significantly increase The authors concluded that these

previous studies the level of chromosome aberrations or SCEs data do not provide any supporting

generally indicated above control values in any of the experiments; X- evidence that 900-MHz microwave

a lack of irradiation alone caused the frequency of radiation is genotoxic, either alone

cytogenetic chromosome aberrations to increase and MMC or in combination with a chemical

effects on human significantly increased the SCE frequency; however, or physical mutagen. The results

lymphocytes from co-exposure to RF did not significantly alter agree with most of the published

exposure to either of these effects. studies that found no cytogenetic

chromosome radiofrequency effects of 900-MHz fields. The few ´- (chromosome ´- (chromosome

nn nn nn EXP GEN in vitro (RF) fields, genotoxicity no -/- nn nn shelf control ´-

aberrations studies that reported genotoxic aberrations, SCEs) aberrations, SCEs)

with little evidence effects, the effects fluctuating

of synergistic around statistical significance, are

interaction after co- rather puzzling. It is possible that

exposure 900-MHz microwaves may have

mitomycin-C some very subtle biological effects

(MMC), a chemical that cannot be clearly

mutagen (Maes et demonstrated by currently used

al., Environ Mol cytogenetic methods.

Mutagen

Nowadays, due to The RF exposure (low and high frequencz

the wide use of components) increase of the fluid-phase

mobile phones, the endocytosis rate was observed ( approximately

possible biological 1.5-fold), on three different cell types. This

effects of increase is an all-or-nothing type of response that

electromagnetic is occurring for threshold values comprised between

fields (EMF) 1.3 and 2.6 W/kg for the delivered EMF powers and

become a public between 1.1 and 1.5 V/cm for the electric fields

health general EMF, via their electrical

intensities depending upon the cell type. The

fluid-phase endocytosis rate nn nn nn EXP CEF in vitro concern. Despite cell function no -/- nn component, can perturb one of the nn nn nn ↑+ (endocytosis) ↑+ (endocytosis)

electric component of these EMFs is shown to

intensive research, most fundamental physiological

be responsible for the observed increase.

there are no widely functions of the cells-endocytosis.

Variations of frequency or pulse duration of the

accepted theories electric pulses are shown to be without effect.

about the

interactions

between EMFs

and living cells, and

the experimental

data are often









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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn thermal









nn nn









nn nn









nn thermal









nn nn









nn nn









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









Univ. of Kuopio;

SMY02 signal generator

Markkanen, A.; Kuopio Univ.

APOPTOSIS INDUCED BY (Rohde & Schwarz, Munich, cell

Penttinen, P.; Hosp.;

UV RADIATION IS Bioelectro- 2,5 (1exp); 2,5 (1exp); Germany) with a wideband (yeast, cell culture

Naarala, J.; STUK-Radiation 0,872 0,9 (2

Finland

R/A.M., J.N., J.J.); Dept. of Clinical Microbiology, Univ.of Kuopio and Dept. of Pediatrics, Kuopio Univ. Hosp., Kuopio, Finland (J.P.); STUK-Radiation andNuclear Safety Authority, Helsinki, Finland (A-P.S.); Dept. of Environmental Health, Natl. PublicHealth Inst., Kuopio, Finland (P.P.) 0.4 (1exp);

93 Markkanen, A. 2004 ENHANCED magnetics none 217 217 577 577 GSM-like 1 nn 0.4 (1exp); cw = pw close to nn RF amplifier R720FC (RF nn 1 hour acute continuous 0 Saccharomyces nn nn cell (mutant

Pelkonen, J.; and Nuclear (1 exp) exp)

BY AM RF RADIATION IN 25(2) 3.0 (2exp) 3.0 (2exp) Power Labs, Woodinville, cerevisiae, KFy417 yeast)

Sihvonen, A-P.; Safety Authority;

MUTANT YEAST CELLS WA) and KFy437)

Juutilainen, J. Natl. Public

and a modulating unit

Health Inst.









0.05 1) 30

0,15 2

Inst. GLUCOSOAMINOGLYCANS mW/cm 4.2 minutes (pw) rat

2,88 (CW?) organ

94 Matych, S. Matych, S. Occupational Inst. Occupational Medicine, ul. Teresy (GAG) IN THE BRAIN OF

Poland 8, 90-950 Lodz, Poland

1981 Med Pr 32(6) 3 (CW) 1000 1000 1.5 1.5 pulsed nn 0.07 nn nn 6.8 nn above nn nn nn 2) 3-6 hr/day acute continuous 0 (mature,weighing male nn whole body

(PW) 0,75 2 (nervous)

Medicine RATS EXPOSED TO EMF mW/cm 10,8 (pw) 200-250 g)

(CW?)

(cw) 3) ? (cw)









individual loop antennas

(PIOM, Ecole Nationale

INERIS; Superieure de Chimie

EFFECTS OF RF Physique de Bordeaux,

Faculte de

EXPOSURE ON THE

Mausset, A-L.; Medecine de Pessac, France) attached to

GABAERGIC SYSTEM IN the top of the holders above 24

de Seze, R.; Nimes; Brain Res rat histological cut

95 Mausset, A-L. France

INERIS, Parc ALATA, BP 2, 60550 Verneuil-en-Halatte, France, e-mail: Rene.De-Seze@ineris.fr(RR/R.d.S.); Laboratoire de Biophysique 576

2001 THE RAT CEREBELLUM: 0.9 0.9 none 217 217 Medicale, Faculte de Medecine de Nimes, Ave. Kennedy, 30907Nimes Cedex 2,32

576 GSM-like nn nn France (A-L.M., R.d.S.); INSERM U336 Developpement, Plasticite et Vieillissement duSysteme Nerveux, Universite Montpellier Il, Place Eugene Bataillon, BP 106, 34095 Montpellier Cedex5, France (A-L.M., A.P.); Departement d'Information Medicale, Hopital Gaston Doumergue, BP 2

4 cw > pw above nn nn 2 hours acute continuous 0 male (12 sham, 12 whole body

Montpeyroux, F.; Universite 912(1) the animals' heads. The (Wistar) (nervous)

CLUES FROM SEMI- antennas were connected to a irradiated)

Privat, A. Montpellier Il;

QUANTITATIVE

Hopital Gaston 900-MHz RFpower amplifier

IMMUNOHISTOCHEMISTRY (type RFS 90064, RFPA

Doumergue

Artigues-pres-Bordeaux,

France)









McNamee, J. P.;

exposure system described in

Bellier, P. V.; DNA DAMAGE IN HUMAN

0,1; the cell

Gajda, G. B. LEUKOCYTES AFTER

Health Canada; time-division- 0,26; McNamee et al. (2002) study, (cultured human

McNamee, J. Miller, S. M.; ACUTE IN VITRO Radiat Res close to / cell culture

K1A Canada

nada, 96 1C1, e-mail: james_mcnamee@hc-sc.gc.ca(RR/J.P.M., P.V.B., S.G., S.M.M., E.P.L., B.F.L., A.T.); Science Affairs and Statistics Div., Officeof Policy and Program Services, Health Canada, Environmental Health multiple-access Pasture,Ottawa, Ontario, Canada, K1A 0L2 (L.M.)

Environmental 2002 1.9 1.9 none 50 50 6700 6700 Center, Tunney's nn nn 0,92; cw = pw nn with an RF single-pole, nn 2 hours acute continuous 1 leukocytes of nn 5x5 cell

P. Lemay, E. P.; EXPOSURE TO A 1.9 GHz 158(4) above (immune)

Health Center (TDMA) 2,4; double-throw switch healthy

Lavallee, B. F. PULSE-MODULATED RF

10 (Mini-Circuits, model ZFSW-2- volunteers)

Marro, L.; FIELD

46)

Thansandote, A.









McNamee, J. P.; waveguide applicators

Bellier, P. V.; NO EVIDENCE FOR 0,1; 0,1; as described by cell

Gajda, G. B.; GENOTOXIC EFFECTS time-division- 0,26; 0,26; McNamee et al. (2002) and (human,

McNamee, J. Radiat Res 1,18 / close to / cell culture

Ontario, Canada, K1A 1C1, e-mail: james_mcnamee@hc-sc.gc.ca(RR/J.P.M., P.V.B.,USA

97 Lavallee, B. F.; Health Canada 2003 A.T.); 24 H EXPOSURE OF

G.B.G., B.F.L., E.L., FROMBiostatistics and Epidemiology Div., EnvironmentalHealth Science Bureau, Safe Environments Programme, Health Canada, Ottawa, Ontario, Canada, K1A 0L2(L.M.)

1.9 1.9 none 50 50 nn nn multiple-access nn 0,92; 0,92; cw = pw nn Gajda et al. nn 24 hours temporary nn 1 healthy donors, nn nn cell

P. 159(5) 3,54 above (immune)

laMarro, L.; HUMAN LEUKOCYTES TO (TDMA) 2,4; 2,4; (Bioelectromagnetics 23:592- 20-60 yr old

Lemay, E.; 1.9 GHZ RF FIELDS. 10 10 598, 2002; BENER Abstract leukocytes)

Thansandote, A. No. 23946)









The Univ. of 0,39

Texas Health

RF (MW) radiation for 350 MHz; TEM Cell (350 MHz), cell

Meltz ML, Science Center;

exposure of mammalian Radiat Res 4,5 below / or anechoic chamber (tissue culture of cell culture

TX Air Force USA Sciences Div., U.S. Air Force Schoolof Aerospace Medicine, Brooks1.2 Force Base, TXnn

at San Antonio, 7703 Floyd CurlDrive, San Antonio,U.S.78284-7800 (RR/ M.M., K.A.W.); Radiation1987

98 Meltz, M. L. Walker KA, 0.35 Air 0.85 78235-5301 (D.N.E.)

nn nn nn pulsed nn 10 cw = pw nn nn 1; 2; 3 hours acute continuous 1 nn nn cell

cells during UV-induced 110 (2) for 850 MHz; close to with a horn antenna (850 MHz human diploid (muscle-skeleton)

Erwin DN School of

DNA repair synthesis 2,7 and 1.2 GHz) fibroplasts)

Aerospace for 1.2 GHz

Medicine









1,3 0,1;

Merritt, J. H.; USAF Sch. STUDIES ON BLOOD-BRAIN Radiat 0.5

(PW 10 (1,3 1; 20, 30, 35 rat nervous

99 Merritt, J. H. Radiation F.; Div., USAF USA 1978 78235

Chamness, A. SciencesAerospace Sch. Aerospace Medicine, Brooks AFB, TX BARRIER PERMEABILITY Environ 1.2 none 1000 1000 (1,2 pulsed nn / 2 - 75 nn nn above nn nn nn acute continuous 0 male nn whole body

and GHz) 10; minutes (Sprague-Dawley) (BBB)

Allen, S. J. Medicine AFTER MW-RADIATION. Biophys 15(4) GHz)

CW) 50









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The authors UV exposure significantly increased apoptosis and

examined the reduced viability of yeast cells compared to control

effects of cells (p controls.

nn nn nn EXP investigated. pathological -/- yes irradiated rats showed hr/d)

(heparin fraction; NES vitro

Mature male rats changes

hyaluronic acid and 2. experiment (pw): Young male rats were exposed an insignificant

chondroitin sulfate) weighing 200-250 to 2880 MHz energy (pulse modulation, 1000 Hz; increase in the

g were subjected pulse width 1.5 usec) for 3-6 hr/day. At an SAR of heparin and

to a 2.8 W/kg, the animals showed a significant increase chondroitin sulfate

single 30-min in the heparin fraction compared to controls. fractions and no

irradiation at 2880 However, at SARs of 6.5 and 8.0 W/kg, the change in hyaluronic

MHz (pulse irradiated rats showed an insignificant increase acid.

modulation, 1000 in the heparin and chondroitin sulfate fractions

neurotransmitter content of the MHz; pulse

The effects of In rats irradiated with the lower power GSM signal The authors concluded that 900 nn sham-exposure ´- ↓+ (mean optical ´- (mean optical decrease (cw)

central nervous system (CNS) radiofrequency (4 W/kg SAR), the mean OD (MOD) of stained cells MHz exposure at relatively high RF density (MOD) of density (MOD) of

(RF) radiation of did not differ significantly from the MOD of sham- energy levels (SAR of 4 or 32 stained cells) stained cells)

(to localize cellular gamma- the type associated irradiated rats, regardless of the cell layer. However, W/kg) appears to decrease cellular

aminobutyric acid (GABA) in the rat with there was a significant 16% decrease in the area of GABA content in the cerebellum. ↓+ (in the area of ↓+ (in the area of

cerebellum a semiquantitative cellular phones on stained processes in the Purkinje cell layer in Phantom measurements suggest stained processes in stained processes in

immunohistochemical assay with CEF; in vivo -> the changes of the the 4 W/kg exposure would the Purkinje cell layer) the Purkinje cell layer)

yes rat phantom yes EXP -/- yes RF-exposed rats compared to sham-irradiated nn

computerized image analysis was END vitro neurotransmitter endocrine system produce only a small temperature

animals (p at nonthermal cond); at nonthermal cond);

vein) fluorescein across the blood- nn nn yes EXP pathological no -/- nn hyperthermic for changes in nn nn nn

EOR vitro examined in male ↑+ (BBB permeability ↑+ (BBB permeability

brain Sprague-Dawley changes permeability of the barrier induced

at thermal cond) at thermal cond)

barrier rats. At a by microwave radiation to occur.

frequency of 1.2

GHz, the

radiation was

delivered at a

pulse repetition

rate of 1000

pulses/sec, a

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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn nn









nn nn









nn nn









nn nn









nn nn









nn nn









nn thermal









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









Universitat

Wolke, S.; TEM cell connected to a

Bonn; CALCIUM HOMEOSTASIS 16;

Neibig, U.; Bioelectro- pulsed UHF power signal generator cell (myocytes of

Institut fur OF ISOLATED HEART 50; cell

Germany

hrichtentechnik Braunschweig, Braunschweig, Germany (U.N., R.E.); Physiologisches Institut derUniversitat Bonn, Bonn, Germany (F.G., R.M.); Physiologisches Institut 1.8 Universitat Bonn,Wilhelmstr. 31, D-53111 Bonn, Germany (RR/R.M.)

100 Meyer, R. Elsner, R.; 1996 magnetics 0.9 der 1.3 16 2.5 2.5 (square, GSM- 1 7.62 0,009 - 0,059 / cw = pw below nn (SLRD BN 41004/50, Rohde nn 500 seconds acute intermittent 0 heart of adult nn nn cell

Nachrichten- MUSCLE CELLS EXPOSED 217; (cardio-vascular)

Gollnick, F.; 17(2) like) and Schwarz, Munich, guinea pig)

technik TO PULSED HF EMF 30.000

Meyer, R. Germany)

Braunschweig









rectangular waveguides (1.8

0,08; GHz and 900 Mhz)

Universitat Bonn;

Linz, K. W.; MEMBRANE POTENTIAL 0,48; or TEM cell (180 MhZ), cell

Bergische GSM-like; 0,2;

von Westphalen, C.; AND CURRENTS OF Bioelectro- 0,6; exposure system as (heart muscle

Universitat - German police 1,2; mobile cell culture

31, D-53111 Meyer,Germany, e-mail:meyer@physio.uni-bonn.de (RR/R.M., K.W.L., Germany

101 Bonn, R. Streckert, J.; C.V.); Lehrstuhl fur Theoretische Elektrotechnik,Bergische Universitat - Gesamthochschule Wuppertal, 217 (J.S., V.H.)

1999 ISOLATED HEART MUSCLE magnetics 0.18 1.8 0.9 FRG 217 nn nn nn 0.015 0,72; cw ≤ pw below described by nn nn nn nn 0 myocytes of adult nn nn cell

Gesamt- communication 1,8; telephone (cardio-vascular)

Hansen, V.; CELLS EXPOSED TO 20(8) 0,8; Wolke et al. guinea pig and rat

hochschule standard 2,2

Meyer, R. PULSED RF FIELDS 0,25; (Bioelectromagnetics 17:144- ventricles)

Wuppertal

0,015 153, 1996; BENER Abstract

No. 13747)









EFFECT OF

Mezhevikina, L. M.; ELECTROMAGNETIC SHF-

Mezhevikina, Koltun, S. V.; Acad. Sci. RADIATION ON THE Biofizika 45 (waveguide) - 300 waveguide or stripline slot whole body cell

102 Russia Region, Russia

Inst. of Biological Physics, Acad. Sci. USSR, Puschino, Moscow1990 0.915 0.915 none 500 500 1 1 pulsed nn nn cw = pw above nn nn 20 minutes acute continuous 0 embryo (mouse) nn nn

L. M. Goriushkin, G. E.; USSR MORPHOFUNCTIONAL 35(5) (stripline) irradiators (embryo) (embryo)

Tigranian, R. E. STATUS OF EARLY MOUSE

EMBRYOS









RESPONSE OF cell

Mezykowski, T.;

Instytut ASPERGILLUS NIDULANS (Aspergillus

Mezykowski, Bal, J.; J Microw GMC-500 M (SON-4

103 Warsaw

Instytut Medycyny Lotniczej, Krasinskiego 54, Poland 01-755, Poland AND PHYSARIUM

Medycyny 1980 2.45 2.45 none 600 600 1 1 pulsed nn 10 10 nn cw = pw above nn far-field 1 hour acute continuous 0 nidulans; nn nn cell culture cell culture

T. Debiec, H.; Power 15(2) source source)

Lotniczej POLYCEPHALUM TO MW Physarum poly-

Kwarecki, K.

IRRADIATION cephalum)









human

Res. Inst. of MILLIMETER WAVES IN THE

(patients with part: nervous

Miryutova, N. F.; Balneology and TREATMENT OF

Crit Rev 2-channel "Stella-1" stimulator discogenic para-vertebral (treating neuro-

Miryutova, N. Levitskii, E. F.; Physiotherapy; NEUROLOGICAL 42,19 52 - 78 9; 0,75e-3 medical

Res. Inst. of Balneology and Physiotherapy, Moscow, Russia (N.F.M., E.F.L.); Russia Joint-stockCo., Tomsk, Russia (A.M.K., I.M.M.) Biomed Eng

104 Spinor 2001 78 (pw) 9 1 1 pulsed 8.75E-09 nn nn nn below designed for mm-wave nn 2-4 minutes acute intermittent 1 neurological nn 156 sites; endocrinelogical

F. Kozhemyakin, A. M.; Spinor Joint- MANIFESTATIONS OF (pw) (cw) 10 (noise); 0,001 application

29(5-6) therapy symptoms dermatome symptoms of vertebral

Mavlyautdinova, I. M. stock VERTEBRAL

of vertebral sites osteo-chondrosis)

Co. OSTEOCHONDROSIS

osteochon-drosis)









Ukrainian Acad.

of Agricultural

Sciences;

Mishenko, A. A.; insect

State

Malinin, O. A.; 0,0475 wave-pass tube (waveguide) (Sitophilus

Aerospace Univ. COMPLEX HIGH- J Microw

Rashkovan, V. M.; 2,45 (PW); 5 - 60 granarius L.,

Mishenko, A. "Kharkov FREQUENCY TECHNOLOGY Power 0,01 2.3 - 2.8 microwave to which RF fields from an chronic -

105 Basteev, A. V.; Ukraine

Inst. of Experimental and Clinical Veterinary Medicine, Ukrainian Acad. of Agricultural Sciences(A.A.M., O.A.M.); State Aerospace Univ. "Kharkov Aviation Inst." (V.M.R., A.V.B., L.A.B.); Natl.Scientific Center "Kharkov Inst. of Technical Physics" (Y.P.M., V.A.K.)

2000 (PW, 0,900 1 1-2 nn nn pulsed nn nn nn nn nn seconds; continuous 0 Sitophilus oryzae nn nn whole body whole organism

A. Aviation Inst."; FOR PROTECTION OF Electromagn (PW) (cw) killing HF generator and modulator multi

Bazyma, L. A.; CW) (PW, few days L., Tenebrio molitor

Natl. Scientific GRAIN AGAINST PESTS Energy 35(3) were applied

Mazalov, Yu. P.; CW) L., and Alpitobius

Center "Kharkov

Kutovoy, V. A. diaperinus Pz)

Inst. of

Technical

Physics"









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The authors In resting control cells, the mean [Ca++]i was 154

examined the +/- 20 nM and remained stable through the 120-min

effects of pulsed duration of the experiment. After treating the control

radiofrequency cells with 135-mM K+ (depolarization at the

(RF) radiation of maximum [K+] used), the average [Ca++]i increased The authors concluded that

the type emitted to 523 +/- 58 nM. No significant effects of RF A small decrease of [Ca++]i in ventricular myocytes

from modern radiation on [Ca++]i under any of the [Ca++]i at 50-Hz from guinea pigs is not affected by

digital wireless experimental conditions were seen. pulse-modulated 900- pulsed 900 to 1,800-MHz RF

changes in fura-2 telecommunications

CEF; MHz exposure; radiation. The negative findings do sham exposure /

fluorescence; nn nn nn EXP in vitro devices on cell function no -/- nn ´- ´- ´-

CVS however its mean not exclude the possibility of cell- shelf control

Ca++ concentrations intracellular value fell within the level effects of high-frequency RF

calcium ion standard deviation of fields on Ca++ levels in ventricular

concentration the control value. myocytes, but make such effects

([Ca++]i) in seem less possible.

isolated heart cells

under athermal

exposure

conditions.

Myocytes were

The effects of None of the RF field exposures significantly

pulsed RF fields on It was concluded that RF fields

affected the MP, AP, L-type Ca++ currents, or

the membrane pulsed according to the GSM

the K+ current in either the rat or guinea pig

potential (MP) and standard or continuous RF fields

preparations. Lowering the temperature (from 36

currents simulating frequency modulated

to 24 C) decreased the amplitude of the L-type

of isolated heart police mobile communications do

Ca++ current by about 50% and shifted the voltage

muscle cells were not interfere with the measured

dependence of the steady state activation and

membrane potential (MP), studied to assess electrical parameters of myocytes.

deactivation parameters of the current by about 5

action potential (AP), the potential of Because long-term effects were /↓++ (Ca++

BMP; mV. The APD90 was increased by about 30%. sham-exposure ´- (ion currents at low ´- (ion currents at low

L-type calcium fix nn no EXP in vitro fields characteristic membrane function no -/- nn not tested and only effects that nn current at low

CVS Irradiation with 900-MHz, 250-mW/kg or 1,800- /shelf control and highet temp) and highet temp)

(Ca++) current, of Global System depend on voltage-gated cells temp)

MHz, 480-mW/kg RF fields had no effect on the

potassium (K+) current for Mobile were tested, it cannot be

current at the lower

Communications definitively stated that RF fields do

temperature.

(GSM) not affect excitable cells. However,

phones and police these results make an influence of

radio equipment to RF fields pulsed according to the

interact with GSM standard on cell membranes

excitable cells. less likely.

Myocytes from

Early mouse No morphological effects of microwaves in 2-

embryos at the and 4-cell embryos. However, in 65% of the 8-

stages of 2, 4, or 8 cell embryos changes similar to those occurring

cells were exposed naturally in later stages of embryo development

for 20 were detected. The cells became more plain

min to 915-MHz and cell surface contacts increased. The effect

microwaves, CW was reversible within 30 min after exposure. The authors suggested that

or PW (500 Hz, 1- Further development to the blastocyst stage was the local nonuniformities of

msec pulse width). local non-uniformities ´- (morphological ↕+ (morphological ↕+ (morphological

morphological changes, EOR; same in control and exposed embryos. C57BL/6 microwave heating ("hot

yes embryos yes EXP in vitro Either teratogenity no -/- of MW heating ("hot nn sham exposure changes in 8-cell changes in 8-cell changes in 8-cell

cell development TER mouse embryos appeared to be more sensitive to spots") could account for the

waveguide or spots") could account embryos) embryos) embryos)

microwaves than those from the hybrid mice CBA x observed electromagnetic field

stripline slot C57BL/6 and CBWA. The differences in exposure effects.

irradiators were conditions (CW or PW, waveguide or stripline) were

used. Microwaves of no importance. Conventional heating of the

heated the embryos to 28-30 C did not induce any considerable

embryos from 20 morphological changes.

C to 25-28 C; this

heating

corresponded to

The effect of After exposure, no changes in survival rate or in

microwaves (MW) frequency of morphological mutation in A.

on genetic nidulans. In P. polycephalum, conventional

processes in heating accelerated DNA synthesis about 2.5 times

Aspergillus nidulans in comparison with the controls, while MW

and Physarum These results do not

irradiation increased DNA synthesis almost 5

polycephalum was lead to the conclusion that the

times.

investigated. observed accelerated effect is of a

survival rate and frequency of Mutants of A. field-specific character or the result

cell vitality;

morphological mutation (Aspergillus yes suspension nn EXP GEN in vitro nidulans no -/- nn of simple thermal activation. The nn shelf control ´- ´- ´-

genotoxicity

nidulans) cultures were accelerated synthesis may reflect

irradiated in the far more efficient volume heating by

field in an anechoic MW or microthermal gradients in

chamber for 1 hr suspensions.

at 10 mW/cm2

using a 2450 MHz

continuous wave

(CW) GMC-500

The or pulsed

sourceauthors Subjective pain relief: significant in nearly all

discussed their patients of group I (combined noise and pulsed mm-

experience with a wave), with 56% reporting their pain completely

new millimeter disappearing; improvement in 70% of the patients in

wave (mm-wave) The authors concluded that

groups II (noise therapy) and III (PW only) , with

technique for 48% of group II and 26% of group III reporting combined mm-wave therapy based

treating on noise and pulsed signals The success of the combined

complete pain dissappearance. However, 3 patients

neurological in group III reported an intensification of their pain produces analgesic and trophic mm-wave therapy was

symptoms of sensations after the first 2 or 3 treatments, which effects. Combined mm-wave ascribed to using 52-78 GHz ↑+ (pain relief; pain ↑+ (pain relief; pain

SEN; in vivo changes of the

pain thresholds nn nn nn EXP vertebral no -/- nn therapy can also affect the radiation that included all nn nn thresholds; tension thresholds; tension

VNS patients neurological system persisted for 1 or 2 hr. Tension symptoms: most

osteochondrosis. functional activity of electrically frequencies carrying symtoms releif) symtoms releif)

pronounced relief in group I. Pain thresholds:

The technique was excitable regions of nerve fibers. physiologically significant

increased 2- and 3-fold in 89% of group I and in

based o applying 2 The combined therapy can information.

85% of group II; no significant changes in group III

types of mm-wave therefore be used to treat patients

patients.

radiation: with neuro-muscular disorders.

continuous wave

noise spanning the

52 to 78 GHz

frequency range,

Grain fodder is Representative data showed that 0.5-msec pulsed The authors concluded that use of nn nn nn ↓+ (killing rate, ↓+ (killing rate,

often highly 47.5-MHz radiation, pulse HF technology can eradicate many proportional to proportional to pulse

contaminated with radiation power of 0.940 J/cm2, applied to grain grain storage pests in an irradiation time) radiation power)

pests, such as samples infested with S. environmentally safe manner.

insects, granarius larvae and adults for 5 to 60 sec killed ↑+ (temperature in increase (cw)

mites, microscopic 71.3 to 96.2% of the the samples) ´- (temperature in the

fungi, and other organisms. The death rate for 60-sec exposure rose samples)

microorganisms, from 42.5% at 1.8 kV/cm, to 53.8% at 2.8 kV/cm,

grain which reduce its growth; and 71.3% at 3.5 kV/cm (representing pulse

killing rate yes yes EXP GRO in vivo nutritional value -/- yes nn

samples life span radiation powers 0.245, 0.615, and 0.940 J/cm2,

and are source of respectively). However, the duration of irradiation

toxic substances. had little effect on S. granarius lethality, the

This study was part proportion of insects killed following irradiation for 5,

of a project 10, 20, and 60 sec being 85.5, 96.2, 89.3, and

dedicated to 71.3%, respectively. This suggested that if the E-

finding alternatives field strength under these conditions was

to chemical increased to 4.0 to 5.0 kV/cm, kill rates of 95 to

disinfection and 100% might be obtained. Irradiation under these

disinfestation for conditions also did









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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn nn









nn nn









yes athermal









nn nn









nn nn









nn thermal (cw)

athermal (pw)









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=







0,35; 0,69;

0,23; 0,48; 1,73; 4,31;

1,19; 2.29; 11.21 for

Morrissey, J. J.; Motorola Corp.; IRIDIUM EXPOSURE 7.79 for average

0,10; Carousel Irradiator described

Raney, S.; Goodwin Inst. for INCREASES C-FOS rostral brain; 0,80;

0,20; below / by Swicord et al.

Heasley, E.; Cancer Res.; EXPRESSION IN THE Neuroscience forebrain; 1,62; 4,05; mouse organ

33322 (RR/J.J.M.); Goodwin Inst. forCancer Res., 1850 NW 69th Ave., Plantation, FL 33313 (S.R.,1999 P.R., M.D.); Dept. of Anatomy andNeurobiology, Univ. of California at Irvine, Irvine, CA 92697 (J.H.F.)

106 Morrissey, J. J. USA E.H., 1.6 1.6 none 11 11 9200 9200 IRIDIUM 0,50; nn cw ≤ pw close to / nn (Bioelectromagnetics 20:42- near-field 1 hour acute continuous 0 male nn whole body

Rathinavelu, P.; Univ. of MOUSE BRAIN ONLY AT 92(4) 0,22; 0,44; 10,11; 26,29/ (BALB/c, adult) (nervous)

1,25; above 47, 1999; BENER Abstract

Dauphinee, M.; California at LEVELS WHICH LIKELY 1,10; 2,75;

3.25 No. 18690)

Fallon, J. H. Irvine RESULT IN TISSUE HEATING 7,14 for 0,19; 0,39;

mid-caudal 0,99; 2,47;

forebrain 6.42 /

whole body









1 or 7 hours;

7 hours/day

for

15 or 60

days (cw, female

Navakatikian, M. A.; Marzeev Sci.

THE EFFECT OF MW 0,0001; Fischer 344 male (Fisher

Gordienko, V. M.; Res. Inst. of 0.001 0,0005; rat

Navakatikian, IRRADIATION ON THE Radiobiologiia 2,45 cw pw intermittent (thyroid gland)

Nogachevskaia, S.I.; Communal Mongrel female)

GLAND mW/cm2 12 hours/day female

Tomashevskaia, L. A. Hygiene,

for (mongrel rats)

1, 15, or 60

days (pw,

Mongrel

female rats)









25; molecule (enzyme:

Studies on the interaction of Radiat 125; acetylcholinesterase

Olcerst RB, New York Univ. pulsed 30 minutes; biological molecules;

108 USA NY radiation with

Olcerst RB, Inst. Environmental Medicine, New York Univ. Medical Center, 550 First Ave., New York, MW10016

1978 Environ 2.45 2.45 none 710 710 750 750 nn 21; nn cw = pw above nn nn nn acute continuous 0 in aqueous solution nn nn model system

Rabinowitz JR Medical Center (square) 3 hours cell-free system

cholinesterase. Biophys 15(3) 35; and defibrinated

64 rabbit blood)









U.S. Army

MW ALTERATION OF THE 0,03/60-1600

Oscar, K. J.; Mobility Brain Res pulsed above / rat nervous

109 Oscar, K. J. Equipment 1977D Command, Fort Belvoir, VA 22060

U.S. Army MobilityUSA R& BLOOD-BRAIN BARRIER 1.3 1.3 none 5 5 - 1000 0.5 0,5 - 20 nn 0.3 - 2.0 nn cw ≥ pw nn nn nn 20 minutes acute continuous 0 male nn nn

Hawkins, T. D. Equipment R & 126(2) (square) close to (Wistar) (BBB)

SYSTEM OF RATS 0,5 - 2,0

D Command









Pakhomov, A. G.; ABSENCE OF NON- G3-24 VHF signal generator

USSR Acad. of with a 50-mW, 50-ohm coaxial nerve (ventral nerve

Pakhomov, A. Dubovlck, B. V.; THERMAL MW EFFECTS ON J Bioelectr 100; 0,5; 10 - 50 part: cell

110 Inst. of Medical Radiology, USSR Acad. of Medical Sciences, Obninsk, Kaluga Region, 249020, USSR

Medical USSR 1991 6.45 6.45 none 100 0.5 pulsed nn nn up to 200 up to100 / nn above nn nn acute continuous 0 cord of earthworm nn nn

G. Kolupayev, V. E.; THE FUNCTION OF GIANT 10(1&2) 1000 5 output feeding a minutes nerve (nervous)

Sciences Lumbricus terrestris)

Pronkevich, A. N. NERVE FIBERS microstrip slot irradiator









HP 8690A

model 337X

sweep

magnetron

COMPARISON OF DOSE oscillator and

McKesson transmitter

Pakhomov, A.; DEPENDENCES FOR Hughes cell:

BioServices; (Applied

Gajsek, P.; BIOEFFECTS OF CW AND Bioelectro- 1277H Saccharo-

Pakhomov, A. W.R. Army Inst. pulsed 1,25 / cw = pw Systems cell cell culture

S Army Medical Res. Detachment of the Walter ReedArmy Inst. of Res., Brooks AFB, USA Antonio, TX (B.E.S.); Directed Energy Bioeffects Div., HumanEffectiveness Directorate, Air Force Res. Lab., Brooks AFB, San Antonio, TX (A.G.P., M.R.M.); Natl.Inst. of Public Health, Ljubljana, Slovenia nn

111 Allen, L.; San 2002 HIGH-PEAK POWER MW magnetics 9.3 9.3 none 10 10 0.5 0.5 nn (P.G.) nn nn amplifier nn 6 hours acute continuous 0 nn nn myces

G. of Res.; (high power) 250 000 (1.25 W) Engineering, (yeast) (growth of yeast cells)

Stuck, B. E.; EMISSIONS USING GEL- 23(2) cervisiae, strain

Natl. Inst. of Inc.) and

Murphy, M. R. SUSPENDED CELL and BY474

Public Health HP 8566B

CULTURES. HP 8566B

spectrum

spectrum

analyzer

analyzer









waveguide waveguide

flange flange

McKesson

exposed with exposed with

BioServices; EFFECTS OF HIGH POWER histological cut

Pakhomov, A. G.; an a model 337X organ

Walter Reed MW PULSES ON SYNAPTIC Bioelectro- (synaptic transmission

Pakhomov, A. Doyle, J.; pulsed nn 250; 1000 / HP 8690A magnetron (hippo-campus of cell:

Army Inst. Walter Reed Army Inst.USA

(RR/A.G.P., J.D.); U.S. Army Medical Res.Detachment of the of

112 of Res., Brooks Air Force Base, San Antonio, TX (B.E.S.);Directed Energy Bioeffects Div., Human Effectiveness Directorate, Air Force Res. Lab., Brooks AirForce Base, San Antonio, TX (A.G.P., M.R.M.)

2003 TRANSMISSION AND LONG magnetics 9.3 9.3 none 0.5 10 0.5 2 / 260 250; 1000 cw = pw above nn nn 7 minutes acute continuous 0 male 160 and

G. Stuck, B. E.; (high power) 500 000 000 sweep transmitter rat, Sprague hippocamal

Res.; TERM POTENTIATION IN 24(3) long-term potentiation

Murphy, M. R. oscillator and (Applied Dawley)

Air Force Res. HIPPOCAMPUS in hippocampal slices)

a Hughes Systems

Lab.

8020H Engineering,

amplifier Inc.)









6 minutes /

EFFECT OF GSM 900-MHz GSM phone day for 5

GSM phone Drosophila melano-

Panagopoulas, D. J.; MOBILE PHONE RADIATION Electromagn speaking days groups of 10

Panagopoulas, mobile non-speaking gaster (strain

113 Karabarbounis, A.; Univ. of Athens Dept. of Cell Biology and Biophysics, Faculty of Biology, Univ. of Athens, Panepistimiopolis,15784, Athens, Greece, e-mail: dpanagop@cc.uoa.gr (RR/D.J.P.; L.H.M.); Faculty of nn

Greece 2004 ON THE REPRODUCTIVE Biol Med 0.9 0.9 none 217 217 nn nn GSM-like Physics, Dept. ofNuclear and Particle Physics, Univ. of Athens, Athens, Greece (A.K.) above

0.041 0,436/ nn cw molecular limits established by the FCC for cellular phone expression at

c-fos mRNA expression nn nn nn EXP CEF IRIDIUM operating no -/- nn coupled with effects of restraint nn control/ positive expression at higher expression at higher

vitro biosynthesis exposure in humans. No difference between the higher exposure

signal is used for a and/or normal control (gavaged exposure levels) exposure levels)

effects of CW and IRIDIUM RF radiation. The 2nd levels)

ground-to-satellite- neuron activity near with lindane)

highest radiation doses increased c-fos expression in

to-ground cellular thermoregulatory brain regions,

the cingulate cortex and prepiriform cortex (known to

communications and is not consistent

be involved in emotional and stress responses and

web which has with any direct modulation-specific

thermoregulation) but not in any other brain regions,

recently become interaction of IRIDIUM energy with

nor did the 3 lower doses.

fully operational, brain tissue.

and was named on

the basis

A previous series Male rats showed triiodothyronine levels in their ...and this fact indicated thyroid nn nn nn ↑+ ( 2450 MHz, ↓+ ( 2450 MHz, contrary effects

of experiments blood serum index 1.5 x higher and thyroxine 1.5 gland participation in the adaptation functional activity of functional activity of

studied possible times less than female rats exposed to the same reaction to MW. the gland) the gland)

effects on thyroid conditions. Histological analysis of thyroid gland

functional activity of the thyroid gland samples showed that exposure to continuous 2450

gland function and on the MHz MW increased the functional activity of the

(triiodothyronine and behavior of mature gland, while exposure to pulsed 3000 MHz MW

thyroxine levels in the blood serum) mongrel and decreased its activity. Similar effects were

BEH; Fischer 344 rats

changes of the described previously (Koziarin I.P. and Shvaiko I.I.,

nn nn nn EXP in vivo exposed -/- yes nn

modifying effects of END endocrine system Gig Sanit 3:86-89, 1983; BENER Abstract No.

thyroidectomy (TE) on behavior in to microwave 1217). Comparison of the behavior of rats in each

mongrel rats (animals were irradiation (MW). group showed that TE decreased central nervous

evaluated for locomotory activity in No significant system (CNS) activity, developing after a 14-day

a labyrinth test) changes in serum exposure to MW (17.2 +/- 1.2, 25.9 +/- 2.3, 20.1 +/-

levels 2.1, and 18.2 +/- 2.5 for A, B, C and D groups,

("blood serum respectively). After 30 days of TE with MW the

index") of thyroid animals showed significant activation of their

gland hormones behavior compared to unexposed TE, treated

thyroxine and CW and square fact modulated irradiation

animals, and thiswaveindicated thyroid glandhad no

effect on the total cholinesterase activity and in

morphological and the levels of magnesium and calcium in cell-free These studies showed no direct

activity of external

A 30-min uncooled exposure at a power density of 125 mW/cm2 caused a significant drop in the initial velocity of theserum in a temperature controlled system.

mples of the purified enzyme in aqueous solution and control samples.yes

fix EXP ENA in vitro pathological no -/- enzyme. However, in this experiment, the temperature was allowed to rise during irradiation and was 60 C after 30 min. At this temperature, thermal denaturation would cause irreversible changes in the enzyme structure. Microwave radiation of defibrinated rabbit blood had no effect on the total cholinesterase activity at levels of 21, 35, and 64 mW/cm2 for both continuous wave and sq

nn effect of microwave radiation on nn shelf control ´- (enzyme activity) ´- (enzyme activity) ´- (enzyme activity)

acetyl-cholinesterase medium

changes Effects were observe when the ext temperature was acetylcholinesterase activity.

not controlled.



The effect of A single 20-min exposure to either pulsed (square Microwaves appear to induce nn nn nn ↕+ (mannitol uptake, ↕+ (mannitol uptake, amplification (pw,

microwave temporary changes in the 2 2 depending on PFD)

wave) or continuous wave (CW) 1.3 GHz 0.3 mW/cm to 0.03 mW/cm )

exposure on the microwave energy induced an increase in the permeability of the blood-brain cause the same

uptake of uptake of radiocarbon-labeled D-mannitol at system of rats for small molecular magnitude of change

saccharides in the average power densities of less than 3.0 weight saccharides. as pw)

brain mW/cm2. The permeability change was greatest in

of male Wistar rats the medulla, followed in decreasing order by the The effect of peak power on

were studied. A cerebellum and hypothalamus, with small or mannitol seemed to be greater

single 20-min morphological and

BBB; in vivo -> negligible changes in the hippocampus and cortex. than the effect of pulse width,

uptake of saccharides in the brain nn nn nn EXP exposure to either pathological -/- yes nn

NES vitro Although permeability increases were observed for and both appeared to have a

pulsed (square changes

mannitol as well as for inulin, they were not greater effect on permeability

wave) or observed for dextran. In general, mannitol uptake than the pulse rate.

continuous wave increased with increasing power density for

(CW) 1.3 GHz both pulsed and CW microwave signals up to

microwave energy 0.5-2.0 mW/cm2 where the brain uptake index

induced an (BUI) started to level off and then decrease.

increase in the Increased permeability was observed both

uptake of immediately and 4 hr after microwave exposure

radiocarbon-

Functional activity Different combinations of microwave parameters,

in the giant axon of either synchronous or asynchronous with stimuli, did The authors concluded that there

the isolated ventral not affect nerve function, as determined by was no evidence of athermal

conductivity and action potential

external nerve cord of significant changes in AP latency or conduction in microwave effects on the function

(AP) latency in the giant axon of the fix yes EXP SIG in vitro membrane function no -/- nn nn shelf control ´- (nerve function) ´- (nerve function) ´- (nerve function)

medium the earthworm exposed compared to unexposed nerve fibers. of the giant axon of the ventral

isolated ventral nerve cord

(Lumbricus nerve

terrestris) was cord of Lumbricus terrestris.

examined during

The authors Maximum cell density was measured at a distance The biological

compared dose- of about 6 mm above the matching plate, where the PW radiation may exert a specific

effects of CW and

response effects in temperature during exposure was 35 C (optimal) effect on yeast cell growth, with a

PW irradiation were

the growth and of about 7 mm for CW and PW. The cell threshold at a peak SAR of

somewhat different

response of density in the remaining slices decreased sharply 20-30 W/kg. The authors

in the first 3 slices.

yeastcells toward the matching plate and more gradually away concluded, however, that high

For example in the

(Saccharomyces from it, as would be expected from the temperature power PW irradiation of yeast cells

first slice(the highest

cervisiae, strain distribution curve. (local maximum at the exposed gel

SAR) relative growth

cell density; BY474) to surface) did not produce specific

gel nutrient cell vitality, cell was 110.2 +/- 3.3% of control (matching

OD; yes yes EXP CEF in vitro extremely high no -/- bioeffects when compared to CW nn nn no specific bioeffects no specific bioeffects

medium division the control value after temperature)

SAR power microwave radiation at the same

EHPP irradiation and

pulse (EHPP) and average SAR, although this

96.1 +/- 7.6% of the

continuous wave conclusion is tentative and could be

control value following

(CW) microwave "adjusted" in the future by using

CW irradiation. This

radiation using more sophisticated and accurate

difference was

gel-suspended cell techniques. Any specific EHPP on

not statistically

cultures. Yeast cell cell growth would be minuscule,

significant (Student's

suspensions were even if it proves to be real.

paired t-test). No

prepared in a gel

The authors At 4 min (8 min into the experiment) the PS significant differences The authors concluded that the

examined the amplitude increased to 162 +/- 5% of the initial value only microwave

effects of in sham exposed controls, but only to 146 +/- 5% effect observed in these

extremely short, and 132 +/- 8% under EHPP exposure at 0.25 and 1 experiments was a transient PS

Population spikes (PS); tetanic tissue high power kW/kg, respectively. CW radiation exposure suppression that occurred during

microwave produced similar departures from sham control ↑++ (PS amplitude

stimulation of LTP or synaptic yes (hippocamp yes EXP SIG in vitro organ function no -/- nn irradiation. The suppression, which a thermal mechanism sham exposure ↑+ (PS amplitude) ↑+ (PS amplitude)

pulses (EHPPs) on values, increases to 146 +/- 9% and 131 +/- 8% of by LTP induction)

transmission al slices) occurs uniformly in potentiated and underlying the PW effects.

synaptic the initial values at 0.25 and 1 kW/kg, respectively. nonpotentiated PSs, reflects an

transmission and At a 1 kW/kg SAR, both CW and EHPP exposure effect of irradiation on

long-term decreased the PS amplitude by 20-30% when the PSs themselves rather than on

potentiation (LTP) applied prior to tetanus. This degree of suppression, LTP.

in however, did not change the efficacy of LTP

The authors Reproductive capacity of flies exposed to The authors concluded that RF One proposed mechanism for sham-exposure ´- ↓+ (emergent pupae ↓++ (emergent pupae attenuation (pw)

examined the nonmodulated emissions from the GSM phone in emissions from a GSM phone the observed effects is that per maternal fly, per maternal fly,

effect of Global the first experiment was decreased from an are highly bioactive, causing GSM phone radiation males and females males and females

System for Mobile average 12.2 +/- 0.57 pupae/maternal fly to 9.975 +/- significant alterations in the decreases the rate of germ exposed) exposed)

Telecommunication 0.31 pupae/maternal fly, a decrease of 18.24% reproductive capacity of insects. cell proliferation decrease (pw)

s (GSM) cell phone compared to the control value (p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=

analog digital

cellular cellular

telephone; telephone;

6

Hewlett Hewlett

16 (AM)

Packard Packard

50 (AM

signal signal

Penafiel, L. M.; ROLE OF MODULATION IN square

generator, generator,

Litovitz, T.; THE EFFECT OF MW ON Bioelectro- wave) cell flasks, each

The Catholic pulsed model model 8657B, cell culture: cell culture

114 Penafiel, L. M. Krause, D.; USA

Dept. of Biology, The Catholic Univ. of America, Washington, DC 20064 (D.K., A.D., J.M.M.);Vitreous State none The Catholic 60 (AM America, Washington, DC 20064 (RR/T.L., L.M.P.)

1997 ORNITHINE magnetics 0.835 0.84 Lab., 50 Univ. of nn nn 0.96 nn 2.5 cw = pw close to nn nn 2 - 24 hours chronic continuous 0 (murine L929 nn containing 3

Univ. of America (square) 8657B, with with L929 (muscle-skeleton)

Desta, A.; DECARBOXYLASE ACTIVITY 18(2) or FM, fibroblast) x 10(6)

radiofrequenc radiofrequency

Mullins, J. M. IN L929 CELLS sinusoida

y plug-in plug-in model

l signal)

model 83522A;

65

83522A; Hewlett

600

function Packard

generator 8403A

(TENMA modulator to

Medical Signal from Hewlett

PRELIMINARY SMC1 Rhode Packard

Roberti, B.; Biological Lab. ; 0,6-0,9

INVESTIGATIONS OF THE 1,5-2,0 (185 and Schwarz model 8616

Heebels, G. H.; The Lab. for (10GHz); whole organism

EFFECTS OF LOW-LEVEL Ann N Y hr); super high generator and 185 hours; rat

edical Biological Lab. TNO, Rijswijk 2100,C.; Netherlands; The Lab. for Electronic Developmentsof the Armed Forces, Oestgeest, The Netherlands

115 Roberti, B. Hendricx, J. The Electronic Netherlands 1975 3 10.7 none 769 769 1.3 1.3 pulsed 180 0,5-1,0 nn cw pw (Bioelectromagnetics 19:459- hours embryo fibroblast of

Baty, J. D.; Cancer Biology 468, 1998; BENER muscle-skeleton)

MICRONUCLEI IN C3H multiple access mouse)

Roti Roti, J. L. Abstract No. 18421)

10T(1/2) CELLS (CDMA)









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The authors Exposure to CW 835-MHz microwave radiation The authors concluded that AM nn control ´- ´- (ODC activity) ↑+ (ODC activity; AM increase (pw)

investigated the had no effect on ODC activity, except for a small, microwaves at an SAR of 2.5 16, 55, 60 and 65 Hz)

effects of but statistically significant increase at 6 hr when the W/kg are capable of altering the

extremely low- ODC activity ratio (OAR), defined as the mean value biological activity of cells in ´- (ODC activity; AM 6

frequency (ELF) of the ratio of ODC activity in exposed samples to culture while FM microwaves at and 600 Hz)

modulated and that of matched control samples, was 1.3 +/- 0.2 the same power level appear to

CW 835-MHz (p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=





minidisk

player,

modulated by

THE EFFECT OF CHRONIC a frequency

La Regina, M.; frequency

Washington EXPOSURE TO 835.62 MHz synthesizing Qualcomm

Moros, E. G.; division multiple

Univ. Sch. of FDMA OR 847.74 MHz CDMA MW Beta 1 4 hours/day,

Pickard, W. F.; Radiat Res access (FDMA); 150+/- rat

121 Roti Roti, J. Dept., Washington Univ. Sch.Medicine;

Div.,Radiation OncologyL. USA Louis,MO 63110 (E.G.M., W.L.S., J.L.R.R.); Biostatistics0.8356 0.8477 Univ. Sch. ofnn

of Medicine, Box 8061, 660 South Euclid, St.2003 RF RADIATION ON THE Div., Washington none Box8061, 660 South Euclid, St. Louis, MO 63110 (J.B.); Dept. of Electrical Engineering, WashingtonUniv., St. Louis, MO = pw (W.F.P.)

Medicine,nn nn nn nn 1.3+/-0.5 cw 63130 above nn generator prototype cell nn 5 days/week, temporary intermittent 0 female, male 480 whole body whole organism

Straube, W. L.; 160(2) code division 0.25 (Fisher 344)

Washington INCIDENCE OF (Hewlett- phone (type for 2 years

Baty, J.; multiple access

Univ. SPONTANEOUS TUMORS IN Packard CD-3000)

Roti Roti, J. L. (CDMA)

RATS 8675A),

output spread

by a 4-way

divider









Hook, G. J.; EVALUATION OF Motorola, Inc. signal sources

Radiation and

Spitz, D. R.; PARAMETERS OF frequency

Cancer Biology and the RTL cell

Sim, J. E.; OXIDATIVE STRESS AFTER modulated CW as described by Moros et al.

Div.; Radiat Res 20 - 22 (J774.16 macro- cell culture

122 Roti Roti, J. Washington Univ., R.;

of Radiation Oncology, L. USA

Higashikubo, St.Louis, Missouri 63108 (G.J.H., J.E.S., R.H., E.G.M., J.L.R.R.); Dept. of Radiation Oncology, B180Medical Laboratories, 0.8477 Iowa, Iowa City, Iowa 52242-1181 (D.R.S.); Div. of Biostatistics,Washington Univ., St. Louis,nn

2004 IN VITRO EXPOSURE TO 0.8356 Univ. of none nn nn nn nn (FMCW); code nn Missouri 63108 (J.D.B.) 0,67 - 0,93 cw = pw below nn nn acute nn 0 nn nn cell culture

Washington 162(5) (Bioelectromagnetics 19:459- hours phages (J7) of (immune)

Baty, J. D.; FMCW- AND CDMA- division multiple 468, 1998; BENER

Univ.; Univ. of mouse)

Moros, E. G.; MODULATED RF RADIATION access (CDMA) Abstract No. 18421)

Iowa;

Roti Roti, J. L. FIELDS









cylindrical waveguide system

described by Malyapa et al.

Lagroye, I.;

(Radiat Res 149:637 645,

Anane, R.;

1998; BENER Abstract No.

Wettring, B. A.; MEASUREMENT OF DNA

18045), fed by a 10-kW

Moros, E. G.; ENSCPB; DAMAGE AFTER ACUTE

signal generator cell

Straube, W. L.; Washington EXPOSURE TO PW 2450 Int J Radiat rat

123 Roti Roti, 4511 France

Cancer BiologyDiv.,J. L. Forest Park Blvd., St. Louis, MO 63108, e-mail: rotiroti@radonz.wustl.edu (RR/J.L.R.R.,B.A.W., W.L.S., M.L., M.N.); Dept. of Electrical Engineering,none

2004 2.45 2.45 Washington Univ. Sch. of Medicine, St.Louis, MO 63110 (W.F.P.); Div. of Biostatistics, Washington Univ. Sch. of Medicine, St. Louis, MO63110 (J.B.)

500 500 2 2 pulsed nn 2 1.2 cw = pw above nn (model PH40KB/1708B, nn 2 hours acute continuous 0 male 11 + 11 + 8 whole body (nervous,

Laregina, M.; Univ. Sch. of MHz MW IN RAT BRAIN Biol 80(1) (Sprague-Dawley)

SierraCom, Hopkinton, MA) DNA in brain cells)

Niehoff, M.; Medicine CELLS BY TWO ALKALINE

and a

Pickard, W. F.; COMET ASSAY METHODS

20-W power amplifier (model

Baty, J.;

GRF 5008, GTC RF

Roti Roti, J. L.

Products,

Inglewood, CA)









Laszlo, A.; frequency

THE HEAT-SHOCK FACTOR

Moros, E. G.; domain multiple

Univ. IS NOT ACTIVATED IN cell

Davidson, T.; Radiat Res access (FDMA); below / mobile

124 of Radiation and Cancer Biology, Dept. of Radiation Oncology, Washington Univ. Sch. ofMedicine, St. Louis, MO 63110

Div.Roti, J. L.

Roti Washington USA 2005 MAMMALIAN CELLS nn nn nn nn nn nn nn nn nn 0,6; 5 cw = pw nn nn nn acute continuous 1 (hamster; mouse; nn nn cell cell

Bradbury, M.; 164(2) code domain above telephone

Sch. Medicine EXPOSED TO CELLULAR human mammalian)

Straube, W.; multiple access

PHONE FREQUENCY MW

Roti Roti, J. (CDMA)









Persson, B. R. R.;

INCREASED PERMEABILITY

Salford, L. G.; 58

OF THE BLOOD-BRAIN Ann N Y rat nervous

125 Salford, L. G. Brun, A.; Radiation

Lund Univ. Hosp. Dept. of MedicalSweden Physics, Lund Univ. Hosp., S-221 85 Lund, Sweden (B.R.R.P., J.L.E.,L.M.); Div. none

1992 0.915 0.915 of Experimental Neuro-oncology, Dept. of Neurosurgery, Lund Univ. Hosp., S-221 85 Lund,Sweden (L.G.S.); Dept. of Neuropathology, Lund Univ. Hosp., S-221 85 Lund, Sweden (A.B.)

8 8 - 215 nn nn pulsed nn nn nn nn nn nn TEM-cell nn 1 or 2 hours acute continuous 0 female, male (23 cw, 35 whole body

BARRIER INDUCED BY Acad Sci 649 (Sprague-Dawley) (BBB)

Eberhardt, J. L.; pw)

MAGNETIC AND EMF

Malmgren, L.









Div. of

Experimenta

l

Neurooncolo

gy, Dept. of

Neurosurger

y, Lund EXPERIMENTAL STUDIES 7 hours/day,

Univ., 221 4; 0,0077;

Salford, L. G.; OF BRAIN TUMOUR 5

85 Lund, Bioelectro- 8; 570; 0,016;

Brun, A.; DEVELOPMENT DURING below / days/weeks rat organ

126 Salford, L. G. Lund Univ. Sweden 1993 chem 0.915 0.915 none 4 16; 570 600 (50 pulsed /1-2 nn 1.67 0,030; cw > pw nn TEM-cells nn temporary intermittent 0 female, male 74 whole body

Persson, B.R.R.; Sweden EXPOSURE TO above for a total (Fischer 344) (nervous)

(RR/L.G.S.); Bioenerg 30 50; Hz) 1,00;

Eberhardt, J. L. CONTINUOUS AND PULSED of 9-15

Dept. of 200 0,4

915 MHz RF RADIATION exposures

Neuropathol

ogy, Lund

Univ., 221

85 Lund,

Sweden

(A.B.);

Dept. of









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The authors There were no significant differences among final

examined the body weights or days of survival for either male

effects of chronic or female rats in any group. Majority of animals in

exposure to the 3 groups remained healthy and in good

frequency-division condition. No significant differences in tumor

multiple-access incidence in any organ were found between rats in The

(FDMA) or code- the authors concluded that chronic

division multiple- CDMA or FDMA exposure groups and the sham exposure to 835.62-MHZ FDMA or

histological abnormalities, tumor in vivo -> access (CDMA) exposure group. 847.74-MHz RF

nn nn nn EXP TUM cell-phone cancer no -/- nn nn sham exposure ´- (tumor incidence) ´- (tumor incidence) ´- (tumor incidence)

incidence vitro radiation had no significant effect

like radiofrequency on the incidence of spontaneous

(RF) radiation on tumors

the incidence of in Fisher 344 rats.

spontaneous

tumors

in rats. A total of

480 male and

female Fisher 344

rats were included

The authors Neither FMCW nor CDMA irradiation had any

examined the significant effect on the examined endpoints of

potential of oxidative stress in optimally or sub-optimally

oxidative stress: pro-oxidant frequency- stimulated or NO-inhibited (L-NIO treated) cells.

production, nitrite modulated The authors concluded

(NO2-) production, total glutathione continuous-wave that the results of these

content, oxidized glutathione (FMCW) radiation experiments provide no evidence

sham exposure/pre-

(GSSG) centered at 835.62 that exposure of

exposure (murine

content, glutathione peroxidase MHz and code cell vitality; J7 cells to cell phone-like RF

CEF; interferon or ´- (oxidative

(GSH-Px) activity, manganese- fix nn nn EXP in vitro division multiple molecular no -/- nn signals, at or below the permitted nn ´- (oxidative stress) ´- (oxidative stress)

ENA lippopolysacharide stress)/

dependent access biosynthesis standard

to induce oxidative

superoxide dismutase (MnSOD) (CDMA) radiation SAR levels, causes significant

stress)

activity, and copper- and zinc- centered at 847.74 oxidative stress or significant

dependent MHz, cell phone modulation

superoxide dismutase (CuZnSOD) type radiofrequency of oxidative stress responses.

activity (RF) fields, to

induce or modulate

oxidative stress in

mammalian cell

The authors Gamma irradiation caused a significant increase in The authors concluded that

examined the DNA damage, evidenced by significant increases in exposure to 2450-MHz PW

potential of acute comet length, compared to sham exposure using microwaves at an SAR of 1.2 W/kg

exposure to PW both the Singh et al. or the Olive et al. version of the does not induce detectable DNA Since DNA damage is

2450-MHz damage when 2 variants of the believed to be a first step in

assays. Exposure to PW 2450-MHz microwave

microwaves to comet assay (with or without PK) mutagenesis and a step

radiation was not associated with any detectable

induce DNA are used to detect the damage. involved in many mechanisms

DNA damage using two 2 versions increases in comet length compared with cells

damage in rat These results do not confirm the of neoplastic transformation,

of the comet assay: one, described from sham-exposed rats using both assays.

the negative results of this and sham exposure/

by Singh et al. (Int J Radiat Biol GEN; in vivo -> brain cells, work of Lai and Singh, who ´-/↑++ (comet

nn nn nn EXP assessed using 2 genotoxicity no -/- nn the Malyapa et al. (1998) study positive control (X ´- (comet length) ´- (comet length)

66:23-28, 1994) and the other by NES vitro reported RF radiation-induced length)

versions of the do not support the view that ray)

Olive et al. DNA damage in rat brain cells.

comet assay. This low-level 2450-MHz

(Exp Cell Res 198:259-267, 1992). These results, however, are

study was microwave radiation

consistent with negative results

designed to verify demonstrates mutagenic or

reported in the Malyapa et al.

reports of carcinogenic potential

(1998) study, in which exposure

DNA damage by detectable by the comet assay.

of rats to continuous wave 2450-

Lai and Singh MHz radiation did not induce

(Bioelectromagnetic DNA damage in brain cells. The

s 16:207-210,

Laszlo, A., Moros, No increase in the DNA-binding ability of HSF in

E. G., Davidson, cultured mammalian cells as a consequence of any

T., Bradbury, M., exposure tested, within the sensitivity of our assay.

Straube, W. and

Roti

Roti, J. The Heat-

Shock Factor is not The results do not support the

Activated in notion that the stress response is

Mammalian Cells activated as a

´- (DNA-binding ´- (DNA-binding ability

DNA-binding activity of HSF nn nn nn EXP CEF; TUM in vitro Exposed cell transformation no -/- nn consequence of exposure to nn nn nn

ability of HSF ) of HSF )

to Cellular Phone microwaves of frequencies

Frequency associated with mobile

Microwaves. communication devices.

Radiat. Res. 164,

163-172

(2005).There has

been considerable

interest in the

biological effects

Several reports of Albumin leakage was found in 3/20 control The authors concluded that RF nn control ↑(+) (albumin ↑+ (albumin leakage) ↑++ (albumin leakage) amplification (pw)

have appeared in animals, 11/23 rats exposed to CW microwaves, radiation increases the leakage)

the literature and 28/35 rats exposed to 8-215 modulated 915- permeability of the BBB. While

indicating MHz microwaves. These results indicated that this effect was found for continuous

alterations of pulsed EMFs are particularly effective in altering the radiation, it was even more

the selective permeability of the BBB to albumin. pronounced for pulsed RF

permeability of the radiation at 8-215 Hz.

blood brain barrier

(BBB) following morphological and

leakage of endogenous albumin in vivo ->

nn nn nn EXP BBB exposure of pathological -/- yes nn

and fibrinogen vitro

experimental changes

animals to static

magnetic fields

(SMF), low-

frequency time-

varying magnetic

fields (TVMF),

and/or

radiofrequency

The authors No animals showed any RF radiation induced

conducted a study behavioral changes and changes in rectal The authors concluded that RF

to examine the temperature. All rats (irradiated and controls) radiation administered under the

effects of developed tumors. The size of the necrotic areas conditions

continuous and was not related to irradiation modality, tumor size, or of this study does not promote

pulsed 915-MHz time from inoculation to death. No significant tumor growth. The authors

radiofrequency conjecture that pairs where tumor

differences in tumor size were seen between any

(RF) radiation on size increased more in exposed

irradiated rat and its control and between pulsed sham exposure/ pre-

brain tumor animals may represent

NES; in vivo -> and CW radiation, within the irradiated group. exposure (rat-

tumor growth yes rectal no EXP development in cancer no -/- nn animals that are sensitive to RF nn ´- (tumor size) ´- (tumor size) ´- (tumor size)

TUM vitro glioma cell line for

rats. Seventy four exposure. Additionally, since the

tumorogenesis)

male and female RG2\ strain is very aggressive

F344 rats were (producing tumors within 3 wk), the

inoculated tumor growth\ rate may not be

intracranially with malleable to external stimuli such

5,000 RG2 cells, a as the RF. Additional studies using

rat glioma cell line RF radiation with higher SARs are

originally in progress.

derived from an









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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn nn









nn nn









nn nn









nn nn









nn nn









nn nn









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









TEM-cell

PERMEABILITY OF THE based on that previously

Salford, L. G.; BLOOD-BRAIN BARRIER 8; constructed at the National

Bioelectro- Bureau of Standards

Brun, A.; INDUCED BY 915 MHz EM 16; 570; 0,2 - 3 / 3,3 (50 Hz, rat nervous

y, Lund Univ., 221 85 Lund, Sweden(RR/L.G.S.); Dept. of Neuropathology, Lund Univ., 221 85 Lund, Sweden (A.B.); Dept. of MedicalRadiation Physics, Lund Univ., 2221 85 Lund, Sweden 8

127 Salford, L. G. Lund Univ. Sweden 1993 chem 0.915 0.915 none (J.L.E., B.R.R.P.) 4000 pulsed nn 0.33 (0.2 W) cw pw nn microwave power generator nn temporary intermittent 0 female, male 154 whole body

(50 Hz) 6.670 above for about (Fischer 344) (nervous)

Persson, B. R. R.; WIRELESS CELLULAR 3(6) 217; 1,00; (MCL model 15 222)

3 - 5 weeks

COMMUNICATION 50 0,4









4-217 0,8 - 1,6 /

BLOOD-BRAIN BARRIER W/kg per W of input power

1002

Persson, B. R. R.; PERMEABILITY IN RATS Wireless (4 570; below /

pulsed 2 minutes - rat (630 nervous

130 Salford, L. G. Salford, L. G.; Sweden Univ. EXPOSED TO EMF USED IN

Lund Univ. Hosp. Radiation Physics Dept., Lund 1997 Hosp., S-221 85 Lund, Sweden, e-mail:Bertil.Persson@radfys.lu.se (RR/B.R.R.P.) 4

Networks 0.915 0.915 none 8.3 570 4.000; 0,001 - 10 nn pw: 0.0004 - 0.008 cw = pw ? close to / TEM-cell nn acute continuous 0 female, male whole body

(square) 16 hours (Fischer 344) irradiated, (BBB)

Brun, A. WIRELESS 3(6) 16 6.000 0.02 - 0.08 above

372 sham)

COMMUNICATION 50 0.11 - 0.95

217) 1.7 - 8.3









EFFECTS OF CW, PULSED, pulsed (square);

Sanders, A. P.; Bioelectro-

AND SINUSOIDAL-AM MW 250; amplitude AM: 10; rat organ

131 Sanders, A. P. Joines,c/o Joines, Dept. of Electrical Engineering, Duke Univ., Durham, NC 27706

W. T.; Duke Univ. USA 1985 magnetics 0.591 0.591 none 250 5 5 nn 1,0-13,8 nn cw ≥ pw above nn nn nn 5 minutes acute continuous 0 male nn whole body

ON BRAIN ENERGY 500 modulated (4- 20 (Sprague-Dawley) (nervous)

Allis, J. W. 6(1)

METABOLISM 32 Hz)









Santini, R.; B16 MELANOMA 2,5

INSA; Bioelectro-

Hosni, M.; DEVELOPMENT IN BLACK hours/day mouse

Einstein 69621,R.

lbert132 M.H.); de France

Santini, Villeurbanne,France (RR/ R.S.,Faculte Laboratoire de Chimie Biologique, INSA, Villeurbanne, (H.P.); Laboratoirede Physiologie Immunologie, Faculte de Sciences, Limoges, France (P.D.)

1988 magnetics 2.45 2.45 none nn nn 10 10 pulsed nn 1 1.2 cw = pw above nn nn nn temporary intermittent 0 female nn whole body muscle-skeleton

Deschaux, P.; MICE EXPOSED TO LOW- up to 690 (C57BL / 6J)

Sciences 9(1)

Pacheco, H. LEVEL MW RADIATION hours









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The authors Across all experiments, albumin leakage was

conducted a study detected in 8% of the control animals and 30%

to investigate the in irradiated animals. The difference was

effects of statistically significant. Following irradiation with CW The authors concluded that both

continuous and microwave radiation, 40% of the brain sections CW and pulsed 915-MHz

pulse-modulated stained positively for albumin. Following exposure to microwaves can open up the BBB

915-MHz the pulsed microwaves, 25, 26, 34, and 26% of the for albumin passage, while

These findings also indicate

leakage microwave brain sections from animals irradiated with 8, 16, 50, fibrinogen leakage is rather limited ↑+(albumin

radiation on the morphological and that moderate BBB leakage is ↑++(albumin ↑++(albumin

of the BBB (penetration of albumin in vivo -> and 200-Hz pulsed microwave radiation stained (the fibrinogen molecule is larger leakage),´-

nn nn nn EXP BBB blood brain barrier pathological no -/- nn induced, at least partially, by a sham exposure leakage),´- leakage),´- (fibrinogen

and vitro positive for albumin. The difference in overall than the albumin molecule). The (fibrinogen

(BBB) in rats. changes nonthermal interaction with (fibrinogen leakage) leakage)

fibrinogen) albumin-positive staining between animals exposed question of whether opening the leakage)

Previous efforts to microwave EMFs.

to the pulsed and CW microwave radiation, 28 and BBB represents a health hazard

study BBB effects 30%, respectively, was not statistically significant. requires further investigation as

of microwave No fibrinogen-positive staining was detected. does determining the extent of the

radiation have not thermal effect.

utilized assays with

adequate

sensitivity and

specificity. In a

The authors In microwave-exposed animals, extravasation of

studied the effects albumin was found in traditionally BBB-weak

of pulse-modulated areas as well as in the semioval center on both

microwaves on sides, joined by the callosal body. The

blood brain barrier extravasation was asymmetrical and spotty and was The authors concluded that the

(BBB) permeability frequently found centered around small vessels. localized nature and selectivity of

in rats. Male and The albumin leakage was frequently taken up by BBB leakage (i.e., for the smaller

female Fischer glial and neuronal cells in the vicinity of a capillary. molecular marker only) make this

morphological and

in vivo -> 344 rats were No extravasation of fibrinogen was observed under minor effect rather difficult to ↑+(albumin ↑++(albumin leakage) ↑++(albumin leakage)

albumin; fibrinogen nn nn nn EXP BBB exposed for 2 hr to pathological no -/- nn nn sham exposure

vitro any conditions. When the data were analyzed on a detect. Further investigations are leakage) ´- (fibrinogen leakage) ´- (fibrinogen leakage)

915-MHz cw changes

per rat basis, 5 of 62 controls and 56 of 184 needed to determine if the BBB

microwave exposed rats showed albumin extravasation through effects are thermal or nonthermal

radiation (35 rats) the BBB. CW microwave exposure induced in nature, and if they constitute a

or 915-MHz albumin extravasation in 40% and PW in 28%. potential health hazard.

microwaves pulse The proportion of rats showing extravasation of

modulated at albumin through the BBB did not vary significantly

repetition rates of 8 with pulse rate and SAR. When the exposed rats

(32 rats), were divided into low-SAR and high-SAR groups, a

16 (38 rats), 50 (41

The authors difference inrats showed any signs ofifstress = 2.5

None of the response was detected SAR

examined the associated with irradiation. All 154 pairs of animals

capability of RF developed rounded polycyclic brain tumors with well-

fields of the type defined boundaries. No significant differences in

associated with tumor size between irradiated and sham- The authors concluded that, under

wireless irradiated rats were seen in any experiment. For their

communication example, in rats inoculated with RG2 tumor cells, the experimental conditions, extensive

devices to promote sham exposure/ pre-

mean tumor size in animals irradiated with CW 915- daily irradiation with RF fields

brain exposure (RG2 and

tumor growth NES; in vivo -> MHz radiation and their matched controls was 29 +/- similar

yes rectal no EXP tumorigenesis in a cancer no -/- nn N32 cell ´- (tumor size) ´- (tumor size) ´- (tumor size)

in brain TUM vitro 22 and 18 +/- 13 mm3, respectively (p=0.10, to those associated with wireless

rat innoculation for

Student's t-test) and 20 +/- 15 in PW irradiated and communications devices does not

model. RG2 and tumorogenesis)

20 +/- 17 mm3 in their matched controls , promote

N32 cells, cell lines respectively (p=0.96). growth of transplanted brain tumor

derived from rat cells.

gliomas induced by

ethylnitrosourea,

were injected into

the head of the

right caudate

The authors The average fraction of rats showing penetration of The authors concluded that nn sham-exposure ↑(+) (BBB ↑+++ (BBB ↑+ (BBB permeability; amplification (cw)

examined changes the BBB ("pathological rats") was 0.17 +/- 0.02 exposure to microwave radiation permeability) permeability) 4, 217 Hz)

in blood-brain among sham-exposed controls, and was 0.39 +/- has an unequivocal effect on BBB ↑++ (BBB

barrier (BBB) 0.03 among all irradiated rats exposed at levels permeability under the specified permeability; 8.3, 50

permeability of above 1.5 J/kg, a statistically significant increase experimental conditions. The Hz)

rats exposed to (p modulated 915-MHz radiation, the average

determined by examining the nn nn nn EXP BBB wireless pathological -/- yes nn leakage that may be harmless to

vitro fraction of pathological rats being 0.50 +/- 0.07 and

sections for staining by albumin and communication changes the brain. Nonetheless, potential

0.35 +/- 0.03, respectively, compared to

fibrinogen using devices. Fischer health hazards associated with

corresponding control values of 0.19 +/- 0.05 and

immunohistochemical techniques 344 male and opening the BBB while using

0.15 +/- 0.03 (both p pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









EFFECTS OF MW Neurosci cell

(no affiliation 55 different cell

133 Seaman, R. L. Seaman, R. L. (no affiliation given) USA 1977 RADIATION ON APLYSIAN Res Program 2.45 15 none nn nn nn nn pulsed nn nn nn nn nn nn nn nn nn acute continuous 0 (ganglion of snail nn cell

given) cells (nervous)

GANGLION CELLS. Bull 15(1) Aplysia)









SLOW AND RAPID

2,45 cell

Univ. Texas RESPONSES TO CW AND e.g.

Seaman, R. L.; J Microw 1,5 (PW close to / (Aplysia californica, cell

134 Seaman, R. L. Health Science USA

Dept. Physiology, Univ. Texas Health Science Center, 5323 Harry Hines Blvd., Dallas, TX 75235

1978 PULSED MW none 5000 5000 0,5 0,5 pulsed nn nn e.g. 7 7; nn nn nn nn nn nn nn 0 nn > 37 cell

Wachtel, H. Power 13(1) (PW) and above neuron, abdominal (nervous)

Center RADIATION BY INDIVIDUAL 1 / 400

CW) ganglion, sea-slug)

APLYSIA PACEMAKERS









INTER-BEAT INTERVALS OF

cell

Louisiana Tech CARDIAC-CELL 1,2-12,2 PW cell culture

Bioelectro- (cardiac cell

Seaman, R. L.; Univ., Ruston, AGGREGATES DURING pulsed; close to / cell culture: (cardio-vascular:

dical 135 Seaman, R. L. Tech Univ., P.O. Box 3185, Ruston, LA 71272-0001(RR/R.L.S.); Dept.1993

Engineering, Louisiana USA of Anatomy and Cell Biology, Emory Univ.,magnetics (R.L.D.)

Atlanta, GA 2.45 2.45 none nn nn nn nn nn nn 1,2 - 86,9 cw ≥ pw nn nn near-field 190 seconds acute continuous 0 aggregates of nn 13

DeHaan, R. L. LA; Emory EXPOSURE TO 2.45 GHz pulsed (square) 12,0-43,5 above heart interbeat intervalls of

14(1) White-Leghorn

Univ., Atlanta CW, PULSED, AND SQUARE- square wave heart)

chick embryo)

WAVE-MODULATED MW.









DEPENDENCE OF MW-

biological molecules;

INDUCED DNA

Semin, Iu. A.; Russian Acad. Radiats Biol molecule cell-free system

SECONDARY STRUCTURE

136 Semin, Iu. A. Shvartsburg, L. K.; of Medical Russia

Medical Radiological Res. Centre, Russian Acad. of Medical Science, Obninsk, 249036 Russia

2002 Radioecol 1.05 2.39 2.05 4 4 25000 25000 pulsed nn 0.6 0.06 nn cw > pw above nn radiating antenna aperature far-field 30 minutes acute continuous 0 (DNA of mouse nn nn cell (cell component, DNA

DESTABILIZATION ON THE

Zhavoronkov, L. P. Science 42(2) thymus) from

MOLECULAR WEIGHT OF

thymus)

THE POLYNUCLEOTIDE









Servantie, B.;

Marine-Centre

Gillard, J.; COMPARATIVE STUDY OF

d'Etudes et de

Servantie, A. M.; THE ACTION OF THREE J Microw

Recherches 1.000; 0,15; rat whole organism

d'Application du Service de Sante pour la Marine-Centre d'Etudes et de RecherchesBiophysiologiques appliquees a la Marine, 83800 Toulon Naval, France

137 Servantie, B. Obrenovitch, J.; France 1976 TYPES OF MW FIELDS Power 2.45 9.4 none 1000 0.15 pulsed nn 5 0.7 nn cw > pw above nn nn nn 15 days temporary continuous 0 nn nn whole body

Biophysiologique 2.000 0,5 (white) (behavior)

Bertharion, G.; UPON THE BEHAVIOR OF 11(2)

s appliquees a

Perrin, J. C.; THE WHITE RAT

la Marine

Creton, B. J.









equipment described by

Sidorenko (in: Krylov (ed.),

THE ANALYSIS OF ANIMAL

the Nonlinear Dynamics

BIOELECTRIC BRAIN Bioelectro-

The method for Analysis of nervous

Sidorenko, A. ACTIVITY chem

138 Sidorenko, A. V. Byelorussian Belarus

Dept. of Radiophysics and Electronics, The Byelorussian State Univ., 4 Scoryna Ave., 220050Minsk, Belarus,nn

1999 nn nn e-mail: saetch@1spec.belpak.minsk.by

nn nn nn nn pulsed nn nn nn nn nn nn Electrocortigrams in Different nn nn nn nn 0 rat nn nn whole body (brain electrical

V. INFLUENCED BY MW OR BY Bioenerg

State Univ. Functional States, activity)

THE INTRODUCTION OF 48(1)

Advances in Synergetics,

STRYCHNINE.

BGU, Minsk, p. 168-172,

1997)









funnel

funnel antenna

antenna

fed by a

fed by a

source

source

EFFECTS OF MW consisting of

consisting of

RADIATION AND an

Sidorenko, A. Sidorenko, A. V.; Byelorussian Bull Exp Biol an rat part:

139 Belarus

Byelorussian State Univ., Minsk, e-mail: A.Sidorenko@RFE.BSU.UNIBEL.BY (RR/A.V.S., V.V.T.)

2000 STRYCHNINE ON 42.2 42.2 none 1 1 30 30 pulsed nn 0.15 nn cw = pw close to nn conductivity- nn nn nn nn 0 nn nn nervous

V. Tsaryuk, V. V. State Univ. Med 130(9) conductivity- (bred) head

CEREBRAL BIOPOTENTIALS modulated p-i-

modulated p-i-

IN NARCOTIZED RATS n diode and

n diode and

an ESU-1

an ESU-1

electric

electric

stimulator

stimulator









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



Comparative No difference between the effects of CW and

studies of pulsed radiation for the majority of observations.

microwave and Convectively temperature changes of 0.1-2.7 C

thermal effect on were found to affect the firing rates of white cells.

Aplysia ganglion Irradiation temperature increases were duplicated by

cells were convective heating in 29 white cells. However, ↓+ (interspike interval

performed. ↓+ (interspike interval

decreased interspike interval, as seen in some ´- (interspike in some white cells at

neuronal cell firing rate, interspike Ganglionic in some white cells at

white cells at the onset of irradiation, was never interval in white the onset of

interval, interburst interval, warming was the onset of

produced by a simple rise in environmental /control (convective cells; interburst irradiation; interburst

sensitivity in the lowest effective yes nn yes EXP SIG in vitro produced membrane function no -/- nn nn nn irradiation; interburst

temperature. Likewise, a decreased interburst warming) interval in burster interval in burster

absorbed power, sensitivity of convectively by interval in burster cells

interval in burster cells at the termination of cells at decresing cells at the

extracellular currents introduced flushing warm at the termination of

irradiation was never produced by an temperature) termination of

water through an irradiation)

environmental temperature decrease. The lowest irradiation)

enclosed space effective absorbed power (LEAP) in about 50% of

surrounding the the white cells was less than 15 mW/cm3. The

chamber sensitivity of the white cell to The largest critical

housing the value of the extracellular current density in the test

ganglion. chambers, affecting the white cells was 110 uA/cm2

Microwave

Transmembrane For about 118, the cells, radiation of for 10 Hz,

for DC andhalf of3730, and 8250 uA/cm2 sufficient nn One possible mechanism for control (warming by nn ↕+ (changes in firing ↕++ (changes in firing amplification (pw)

potentials of intensity consistently reduced the firing rate; for the above changes is an effect convection) rate) rate; bei niedrigerem

individual the remainder of the population, effective on one or more of the SAR als cw)

pacemaker intensities reduced the firing rate during most membrane's components,

neurons in the irradiations but increased the firing rate during perhaps by changing the ionic

abdominal others. For all beating pacemakers, post-irradiation conductance or by altering a

ganglion of Aplysia firing rate returned to the pre-irradiation rate after 1- receptor's ability to combine

firing rates, measured as interspike californica were with a chemical agent.

2 min. The smallest SAR that produced slow

interval (ISI) recorded during changes of firing rate was determined for 39

nn nn nn EXP SIG in vitro microwave membrane function -/- yes nn

beating pacemakers from 29 ganglia and was found

(transmembrane potentials of irradiation to be 7 mW/g. In addition to the slow, graded ISI

individual pacemaker neurons) to study the effects changes, rapid changes in ISIs were also observed

of microwaves on in eight beating pacemakers from eight different

excitable cells. For ganglia. A rapid change consisted of an increase in

every beating firing rate within one ISI of the onset of irradiation.

pacemaker Within 25 sec after the immediate decrease in ISI,

studied, a slow the ISI gradually increased until it nearly reached the

change in firing pre-irradiation value. The smallest SAR causing a

measured

rate, There are as The interbeat interval decreased The microwave

rapid change in ISI was 1 mW/g. during CW or

contradictory square-wave modulation exposures at 42.0-86.9 The authors concluded that the

reports in the W/kg, which was consistent with established effects cardiac cells were affected by

literature regarding of elevated temperatures. In the lower SAR range athermal as well as thermal effects

the sensitivity (1.2-12.2 W/kg) pre- and post-exposure interbeat of microwave exposure. They

external of excitable intervals were not significantly different. However, suggested that it should be

interbeat interval yes medium; no EXP CEF in vitro vertebrate tissues organ function no -/- analysis indicated that decreases in mean interbeat nn nn nn nn ↓+ (interbeat intervals) ↓+ (interbeat intervals)

possible to isolate such athermal

sample to microwave intervals during the beginning of CW exposure were effects in experiments at low SARs

frequency larger than predicted based on temperature (below 2 W/kg) with temperature

electromagnetic changes, while the increases at the end were controls within tight limits to

fields under opposite to the small decreases predicted by eliminate thermal effects.

constant temperature changes. With PW exposures at 8.4-

temperature 12.2 W/kg, the observed decrease in mean

In an earlier Continuous and pulse-modulated exposures nn Thus, the results of this study sham-exposure ´- ↑+ (DNA duplexes ↓+ (DNA duplexes contrary effects

publication (Semin produced opposite effects. Comparison with the do not contradict an became more stable) became more

et al., Radiats Biol curves for non-exposed DNA solutions showed that assumption that microwave- instable)

Radioecol 35:36- in the former case (CW exposures), the curves were induced relaxation of DNA

41, flatter and had lower maxima, indicating that DNA secondary structure can be

1995; BENER duplexes became more stable, whereas in the latter explained by generation of

DNA unwinding time Abstract No. acoustic waves in the

case, the curves were steeper and showed higher

13806), the maximal values, implying a more labile structure. molecule.

(melting curves were monitored by authors assumed

changes in extinction at 270 nm, fix nn no EXP GEN in vitro that microwave- genotoxicity -/- yes nn

using a induced

UV-2100 (Shimadzu) destabilization of

spectrophotometer. ) the DNA double

helix may be due

to specific

(nonthermal)

effects of

electromagnetic

(EMF)

field Behavioral The CW and PW (0.5 usec) produced behavioral

perturbations alterations; on the contrary, the PW (0.15 usec)

induced in the produced

white rat were only weak alterations.

studied after two

weeks exposure to

2.45 GHz It is postulated that the action of

continuous wave microwave fields on the behavior of

locomotor activity, emotivity, field, 9.4 GHz, rats is linked to the peak power

watchfulness, nn nn nn EXP BEH in vivo 0.15 usec, 2000 behaviour no -/- nn density and not to the average nn nn nn ↕+ (behaviour) ↕+ (behaviour)

exploratory activity Hz and 9.4 GHz, power density. Moreover, this

0.5 usec, and 1000 action seems to be independent of

Hz microwave the modulation of the field.

fields. Rats were

first

exposed to a 9.4

GHz field

modulated with

2000 Hz, 0.15

The effects of Exposure to impulse modulated microwaves The author concludes that nn pre-exposure ´- ↕+ (ECG changes) ↕++ (ECG changes) amplification (pw)

microwave caused reproducible changes in the ECG microwave irradiation or strychnine

radiation and spectra. For example, irradiation shifted the injection induces reliable changes

strychnine on brain maximum frequency from 10.35 Hz at time 0 to in the ECGs of rats that can be

electrical 28.33-24.4 Hz at 1-2 min after the start of exposure, detected by nonlinear dynamic

activity were then 7.62-4.39 Hz by 5-7 min after exposure. methods.

Electrocortigram (ECG) pattern studied in rats. Irradiation also increased the contribution of higher

(analog of human Electrocortigrams frequency components (12-30 Hz) to the power

electroencephalograms) (ECGs), the animal changes of the spectrum. The response to CW microwaves

nn nn nn EXP CNS in vivo analog -/- yes nn

neurological system showed a less regular pattern. When analyzed by

analyzed by the spectral correction of human nonlinear dynamics, both pulsed and CW

method electroencephalogr microwave radiation caused ECG changes

ams, were indicative of brain power activation.

performed on rats The calculated values of the Ek were close to 10(-

anesthetized with 1 3). Strychnine also induced activation of brain

g/kg ip uretanum. electrical activity, the most pronounced effect being

ECG data were observed 20 min after injection. The maximum

analyzed by the frequency increased from 15.62 Hz at time 0 to

The correction

spectral authors 27.34 Hz after 15 min, thensignificantly decreased

Urethane-induced narcosis declined to 9.08 at 30

summarized their the maximum power in the total ECoG spectrum (4

experiments fold) compared to the baseline control value 10 min

investigating the after urethane administration, CD and SKE.

effects of Microwave irradiation and strychnine induced urethane:↓+(maxim

microwave changes in ECoG spectral parameters that were um power in the

radiation and Changes in ECoG activity

opposite to those induced by urethane. MW of total ECoG

treatment with probably reflect enhanced /pre-exposure

electrocortico-gram (ECoG); narcotized rats caused a shift in the power spectrum spectrum, CD,

urethane and The authors concluded that the excitability of (urethane to ↑+ (maximum power ↑+ (maximum power

correlation dimension (CD); changes of the to higher frequencies; a significant increase in CD SKE);

nn nn nn EXP CNS in vivo no -/- nn effects of the MWS are similar to cerebral structures and depress CNS); in the total ECoG in the total ECoG

standardized Kolmogorov entropy strychnine on neurological system and no significant change in SKE. Strychnine strychnine:↑++

electrocephalogram those caused by strychnine. complex effects occurring in (strychnine to excite spectrum, CD, SKE) spectrum, CD, SKE)

(SKE) caused the same effects as MWs, but more (maximum power

the dynamics of CNS)

pronouncedly: the maximum power in the total in the total ECoG

(electrocorticogram bioelectric processes

ECoG spectrum was increased 3 fold; CD and SKE spectrum, CD,

(ECoG)) activity in showed a significant increase. SKE)

rats. Random

bred rats

anesthetized with 1-

g/kg urethane

(injected i.p.) and

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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn nn









yes athermal









thermal,

nn

athermal









nn athermal









nn nn









nn nn









nn nn









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









Univ. of

CAN ELECTROMAGNETIC

Pau, H. W.; Rostock;

FIELDS EMITTED BY Otolaryngol

Sievert, U.; Federal Inst. for mobile human part: sensoric

: hans-wilhelm.pau@med.uni-rostock.de (RR/H.W.P.) ( U.S.); Federal Inst. forOccupational Safety2005Health, Res. GroupPHONES

140 Sievert, U. Germany and MOBILE 2.7 Vibration, Electromagnetic Fields, Berlin, Germany(S.E.); Inst. for Measurement nn Control Techniques, Univ. of Rostock, Germany (W.W.)

Head Neck 0.8896 0.8896 nn nn nn and nn GSM-like 2.2 nn nn nn nn nn near-field nn nn nn 1 nn 13

Eggert, S.; Occupational telephone (volunteers) ear (ear)

STIMULATE THE Surg 132(1)

Wild, W. Safety and

VESTIBULAR ORGAN?

Health;









Universitatsklinik

CAN MOBILE PHONE mobile mobile mobile

Sievert, U.; und Poliklinik fur Otolaryngol standardized

EMISSIONS AFFECT phone phone phone sensoric

Hals-Nasen-Ohrenkrankheiten, Kopf- und Halschirurgie "OttoKomer," Doberaner Str. 137-9 18057 Rostock, Germany, e-mail: uwe.sievert@med.unirostocke.de(RR/U.S.)

k fur 141 Sievert, U. Eggert, S.; HNO, Kopf- und Germany 2005 Head Neck nn nn nn nn pulsed nn nn nn nn nn nn near-field nn nn nn 1 human nn 12 nn

AUDITORY FUNCTIONS OF emissio emissio emission mobile phone devices (ear)

Pau, H. W. Halschirurgie Surg 132(3)

COCHLEA OR BRAIN STEM? ns ns s

"Otto Komer"









University of

Rostock,

Institute of

Cell Biology

and

Biosystems

Simko M,

Technology, Hsp70 expression and free

Hartwig C,

Division of radical release after exposure cell

Lantow M, University of

Environment to non-thermal radio-frequency Toxicol Lett (monozytes cell line cell culture

142 Simko M Lupke M, Rostock Germany 2006 1.8 1.8 none 217 217 576 576 GSM-like nn nn 2 cw = pw close to nn nn nn 1 hour acute continuous 1 nn nn cell culture

al electromagnetic fields and 161 (2006) Mono (immune)

Mattsson MO,

Physiology, ultrafine particles in human Mac 6 of human)

Rahman Q,

Albert- Mono Mac 6 cells

Rollwitz J

Einstein-Str.

3, D-18059

Rostock,

Germany.









Singh SP, horn antenna

Rai S, Athermal physiological effects

Inst. of fed by a

Rai AK, of MW on a cynobacterium 2,04; cell

Technology; Med Biol Eng pulsed S-band, VHF signal generator

143 Singh SP Tiwari SP, India Dept. Botany, Varanasi-221005, India (A.K.R.,nn

Dept. of Electronics Engineering, Inst. of Technology, Varanasi-221005, India (S.P.S., S.);2.42 of 2.97

1994 Nostoc muscorum: 2.71 10000 10000 S.P.T., S.S.S., J.A.); Banaras Hindu Univ., Varanasi-221005, India (S.R.)

nn nn 1,98; nn cw = pw above nn near-field 1 hour acute continuous 0 (Cyanobacterium nn nn cell culture cell culture

Banaras Hindu Comput 32(2) (square) (S470, ECIL, Hyderabad,

Singh SS, evidence for EM-memory bits 1.92 Nostoc Muscorum)

Univ. India),

Samarketu, in water

near field

Abraham J









Smialowicz, R. J.; ASSESSMENT OF THE

Health Effects 78;

Riddle, M. M.; IMMUNE RESPONSIVENESS Bioelectro- rectangular strip-transmission

Smialowicz, Research Lab., 17,7; 1 hour mouse

144 Experimental Biology Div., Health Effects Research Lab., EPA, Research1982

Weil, C. M.; USA TriangleOF MICE IRRADIATED WITH

Park, NC 27711 magnetics 0.425 0.425 none 250 250 1 1 pulsed nn 7.7 cw = pw above nn nn temporary intermittent 0 female nn whole body immune

R. J. EPA, Research 5; line for 5 days (BALB/c)

Brugnolotti, P. L.; CW OR PM 425-MHz RF 3(4)

Triangle Park 1,25

Kinn, J. B. RADIATION.









Frederic Joliot-

EFFECTS OF MODULATED waveguide:

Curie Natl. Res.

Somosy, Z.; AND CONTINUOUS MW function generator and

Inst. for 0,0024; 0,0024;

Thuroczy, G.; IRRADIATION ON THE 0,000798; 0,000798; microwave generator,

Radiobiology Scanning pulsed 0,244; 0,244; below / embryo cell culture

145 Somosy, Z. Kubasova, T.; Frederic Joliot-Curie Natl. Res.1991 for MORPHOLOGY AND CELL

Hungary Inst. Radiobiology and Radiohygiene, P.O. Box 101, H-1775Budapest, Hungary (RR/Z.S., G.T. 16 L.D.S.); Dept.nn General Zoology, Eotvos nn

2.45 2.45 none 16 T.K, nn of Lorand Univ.,Budapest, Hungary (J.K.)

0,00798; 0,00798; cw = pw nn connected by a directional nn nn nn nn 0 nn nn cell

and Microsc 5(4) (square) 0,24; 0,24; close to (mouse 3T3) (mouse embryo 3T3)

Kovacs, J.; SURFACE NEGATIVE 0,0798 0,0798 coupler and coax waveguide

Radiohygiene; 2,4 2,4

Szabo, L. D. CHARGE OF 3T3 adapter to a TE10 mode

Eotvos Lorand

FIBROBLASTS waveguide

Univ.









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



Objectives In no volunteer could EM radiation-induced

Pulsating nystagmus be recorded. In the human temporal

electromagnetic bone very weak caloric effects could only be found

(EM) radiation in the tissue layers next to the radiation source

emitted by mobile (antenna of the mobile phone), whereas deeper

phones regions (horizontal semicircular canal) seemed

is often unaffected (at least less than 0.1 degrees C).

incriminated for These results do not support the

temperatures of human temporal EOE; in vivo causing tissue changes of the theory that mobile phone-induced

yes tissue (ear) nn EXP alterations by no -/- nn nn nn nn ´- ´-

bones TMP probands neurological system EM radiation may cause caloric

caloric effects. negative effects in the human ear.

In particular, the

eye and the ear

were regarded as

possible "hot

spots,"

with heating up to

1 degrees C, in

which EM radiation

Problems No impact on auditory brain stem reflexes

addressed: recordings in terms of absolute and interpeak

Despite their latencies could be found.

abundant spread,

mobile phones are

suspected by a Together with the results of a

major share of the previous article concerned with the

population to vestibular part of the inner ear, we

There are no adverse

cause adverse can state that there are no adverse

auditory brain stem EOE; in vivo changes of the effects of mobile ´- (auditory brain stem ´- (auditory brain stem

nn nn nn EXP effects on no -/- effects of mobile phone emissions nn nn nn

reflexes EOR probands neurological system phone emissions on reflexes ) reflexes )

health and welfare. on the ear function, at least on a

the ear function.

The ear as the short-term range. Of course, any

sense organ next long-term effects cannot be

to the individual excluded by our study.

device has rarely

been investigated

for short-term

effects in this

regard.

The contemporary Mono Mac 6 cells are capable to internalise UFP,

urban environment and that this phagocytic activity is connected to an

has become increased release of free radicals. This increase (40-

increasingly 45% above negative control) is stronger than the

complex in its effect of heat treatment. On the other hand, none of

composition, the employed RF exposures showed any effects

leading to on free radical levels. Co-exposure of RF and

Therefore, we conclude that in the

levels of the superoxide radical discussions UFP did not potentiate the UFP effect either. Our ↑+(free radical

regarding possible investigated Mono Mac 6 cells, RF

anion or the stress protein heat- molecular investigations showed a significantly increased /positive control levels) ´-(free radical levels) ´-(free radical levels)

yes nn nn EXP CEF in vitro novel health no -/- nn exposure alone or in combination nn

shock protein (Hsp70) in the human biosynthesis Hsp70 expression level by heat treatment in a time- (heat treatment) ´- (HSP) ´- (HSP)

with UFP cannot influence stress-

monocyte cell line Mono Mac 6 effects. Two dependent manner, whereas UFP, RF, or UFP+RF ↑+ (HSP, heat)

factors that related responses.

were without any effect.

recently have

received

considerable

attention are

ultrafine particles

(UFP; pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









EFFECTS OF MODULATED

"Frederic Joliot-

AND CONTINUOUS MW

Curie" Natl. standard horn antenna

IRRADIATION ON fed by a

Somosy, Z.; Res. Inst. for

PYROANTIMONATE 0,2; 0,2; 0,33

Thuroczy, G.; Radiobiology Scanning pulsed TKI (model TR) microwave mouse histological cut

146 Somosy, Z. Hungary H-1775Budapest, none

"Frederic Joliot-Curie" Natl. Res. Inst. for Radiobiology and Radiohygiene, P. O. Box 101, 2.45

1993 PRECIPITABLE CALCIUM 2.45 Hungary (RR/Z.S., G.T., G.J.K.); Dept. of General Zoology, Eotvos Lorand Univ., 0,5;

16 16 nn nn nn Budapest,Hungary (J.K.)

0,5; 0,82; cw = pw above nn nn 3 hours acute continuous 0 male nn whole body

Koteles, G. J.; and Microsc 7(4) (rectangular) generator coupled to an (CFLP) (digestive)

CONTENT IN JUNCTIONAL 1 1 1,64 /

Kovacs, J. Radiohygiene; OMKER function

COMPLEX OF MOUSE generator

Eotvos Lorand

SMALL INTESTINE.

Univ.









as described by Somosy et al.

(Scanning Microsc

"Frederic Joliot- EFFECTS OF MODULATED

7:1255-1261, 1993;

Curie" Natl. MW AND X-RAY

BENER Abstract No. 11756)

Somosy, Z.; Res. Inst. for IRRADIATION ON THE

0,1;

Thuroczy, G.; Radiobiology ACTIVITY AND Scanning pulsed mouse histological cut

147 Somosy, Z. Hungary

"Frederic Joliot-Curie" Natl. Res. Inst. for Radiobiology and Radiohygiene, P. O. Box 101, 2.45

1994 Hungary (RR/Z.S., G.T., G.J.K.); Dept. of General Zoology, Eotvos Lorand Univ., Budapest,Hungary (J.K.)

H-1775Budapest, none

2.45 16 16 nn nn nn 0,5; nn cw = pw above nn (standard horn antenna nn 1 hour acute continuous 0 male nn whole body

Koteles, G. J.; and DISTRIBUTION OF CA++ Microsc 8(3) (square) (CFLP) (digestive)

1 fed by a

Kovacs, J. Radiohygiene; ATPASE IN SMALL

TKI (model TR) microwave

Eotvos Lorand INTESTINE EPITHELIAL

generator coupled to an

Univ. CELLS.

OMKER function

generator)









cw = pw

pw (15 min, 30 seconds

Teng, J.; NO NONTHERMAL EFFECT IEEE Trans 1W) or

Universite rabbit

de Tournai, D. C.; OBSERVED UNDER MW Microw 1; cw (16 min; asymmetrical dipole implanted nn 16 minutes continuous; part:

148 Teng, J. Catholique Belgium

Microwaves Lab., Universite Catholique Louvain, Batiment Maxwell, B-1348 Louvain-la-Neuve,Belgium

1996 4.2 4.2 none 6 6 200000 3 pulsed nn nn nn nn acute 0 (New Zealand nn nn nervous

Duhamel, F.; IRRADIATION OF SPINAL Theory Tech 2 1W) micro-antenna (near-field) (cw) intermittent spinal cord

Louvain seconds albino)

Vander Vorst, A. CORD 44 cw (30 sec,

2W) ? (pw)









standard gain

horn antenna funnel antenna

fed by a

coupled with source

model Litton consisting of

Thomas, J. R.;

EFFECTS OF LOW-LEVEL Industries an 30 min once rat

Finch, E. D.; Naval Medical Ann N Y 2,45 9,6 2,86 clearly whole organism

149 Thomas, J. R. USA Behavioral Sciences Dept., Naval Medical Res. Inst., Bethesda, MD20014 (J.R.T., L.S.B.); Biophysics Div., Environmental Biosciences Dept., Naval Medical Res. Inst.,Bethesda, MD 20014 (E.D.F.,nn

Experimental Psychology Div., 1975 MW RADIATION ON 500 500 1 1 pulsed nn 1,0 - 25 D.W.F.) cw = pw nn model conductivity- far-field or twice a chronic intermittent 0 (Sprague Dawley, male 4 whole body

Fulk, D. W.; Res. Inst. Acad Sci 247 (cw) (pw) (pw) above (conditioned behavior)

BEHAVIORAL BASELINES L5001A modulated p-i- week 60 days old)

Burch, L. S.

driven by a n diode and

custom- an ESU-1

designed electric

regulated stimulator

power supply









COMPARATIVE EFFECTS

Thomas, J. R.; OF PULSED AND CW 2.8- Bioelectro- rat

Naval Medical close to / whole organism

150 Thomas, J. R. Schrot, J.; USA

Naval Medical Res. Inst., Bethesda, MD

1982 GHz magnetics 2.8 2.8 none 500 500 2 2 pulsed nn 1 to 15 mW/cm2 nn cw = pw nn nn nn 30 min acute continuous 0 (albino, 320-330g, male 4 whole body

Res. Inst. above (behavior)

Banvard, R. A. MW ON TEMPORALLY 3(2) 240 day old)

DEFINED BEHAVIOR.









0.001-

SOMATICO AUTONOMIC

0,020; means of a part:

Vagin, Iu. E.; USSR Acad. of FUNCTIONS OF RABBITS 1; 14-mm-aperture antenna

Biol Nauki 0,030; medical "He-Gu" muscle-skeleton;

151 Vagin, Iu. E. Res. L. V.; Russia

Vagina,Inst. of Normal Physiology, USSR Acad. of Medical Sciences, Moscow, Russia

Medical 1985 EXPOSED TO A VHIF EMF 2.375 2.375 none 1 25; nn nn pulsed nn nn nn nn nn 3-10 minutes acute continuous 0 rabbit nn 11

(10) 0,100; application fed by a acupuncture nervous

Batsiuro, S. G. Sciences AT ACUPUNCTURE 100 "Mirta-01" device

0,500; point

POINTS

1,000









right hand right hand

polarized polarized

planar planar

Johannes spiral antenna spiral antenna

Gutenberg- (AEL-ASO (AEL-ASO rat

Vollrath, L.;

Universitat 1658 AA, 1658 AA, AEL- (Sprague-Dawley;

Spessert, R.; NO SHORT-TERM EFFECTS Bioelectro- 0,6 - 0,36 for the rats;

Mainz; close to / AEL-Defense Defense 15 minutes - Dark-Agouti); organ (neuro-

nberg-Universitat Mainz, Becherweg 13, D-55099 Mainz, Germany(RR/L.V., R.S., T.K., M.K.); Deutsche Bundespost Telekom, Forschungsinstitut beim FTZ, Darmstadt,Germany (H.H.)

152 Vollrath, L. Kratzsch, T.; Germany 1997 OF HF EMF ON THE magnetics 0.9 0.917 none 217 217 nn nn GSM-like nn 0,1 - 0,6 cw = pw nn far-field acute continuous 0 nn nn whole body

Deutsche 0,04 for the hamsters above Corporation), Corporation), 6 hours endocrine)

Keiner, M.; MAMMALIAN PINEAL GLAND. 18(5)

Telekom fed by a fed by a hamster

Hollmann, H.

Forschungsinstit Hewlett- Hewlett- (Djungarian)

ut Darmstadt Packard Packard

model 8657 model 3314A

transmitter pulse

generator









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The effects of CW Exposure to the CW fields or to modulated The authors concluded that low- These data support the view sham-exposure ´- ´- (distribution of ´- (distribution of

and modulated low- microwave radiation (0.1 mW/cm2) did not alter frequency modulated microwaves that extremely low-frequency calcium-containing calcium-containing

intensity the distribution of calcium-containing pyroantimonate can alter the calcium distribution in electromagnetic fields may pyroantimonate pyroantimonate

microwave deposits. Irradiation with 0.5 and 1-mW/cm2 tissues without thermal effects. modify the calcium content deposits; 0.1 deposits; 0.1

radiation on the modulated microwaves caused marked changes and/or distribution in cell mW/cm2) mW/cm2)

calcium content of in the distribution of the deposits. The deposits were membranes and disturb

intestinal epithelial now located on the cytoplasm side of the lateral cellular functions regulated by ´- (distribution of ↕+ (distribution of change (pw)

changes in calcium content of cells were studied the calcium signal transduction calcium-containing calcium-containing

membrane, in the tight junction, and in other areas

intestinal epithelial cells, measured in mice. Male pathway. pyroantimonate pyroantimonate

BMP; in vivo -> of the lateral plasma membrane. These changes

by changes in the distribution of nn nn nn EXP CFLP mice were cell function -/- yes nn deposits; 0.5 and 1 deposits; 0.5 and 1

CEF vitro were reversible--24 hr after exposure the

pyroantimonate deposits by whole body mW/cm2) mW/cm2)

distribution of the deposits was similar to that of the

transmission electron microscopy irradiated with CW controls. Exposure to CW microwave radiation did

or amplitude not alter the distribution of the pyroantimonate

modulated 0.1, deposits.

0.5, or 1-mW/cm2,

2,450-MHz

microwaves for 3

hr. The modulated

radiation

The effects of Immediately and 1 and 3 hr after irradiation with 1- The authors concluded that Since both modulated sham-exposure ´- ´- (CaATPase activity) ↓+ (CaATPase decrease (pw)

modulated mW/cm2 modulated microwaves, CaATPase modulated microwave and X-ray microwave and X-irradiation activity)

microwave and X- activity was inhibited on the lateral membrane. irradiation decrease CaATPase have been shown to act on

ray irradiation on The amount and distribution of CaATPase activity activity in small intestine epithelial components of the membrane

calcium 24 hr after irradiation did not differ significantly from cells. signal transduction process

transporting the control values. Irradiation with CW microwaves (i.e., multiple second

Changes in CaATPase activity adenosine did not affect CaATPase activity. Irradiation with 1- messenger pathways including

(by cytochemical technique) triphosphatase Gy X-rays caused a transient reduction in lateral protein kinase C-, cAMP- and

in vivo -> (CaATPase) membrane CaATPase activity. Irradiation with 5-Gy Ca++ dependent

nn nn nn EXP ENA activity in small cell function -/- yes nn mechanisms), they

distribution of CaATPase vitro X-rays, however, caused a decrease in lateral

(by transmission electron intestine epithelial membrane CaATPase activity that persisted for up presumably play a role in

microscopy) cells were to 24 hr. inducing changes in calcium

examined. Male pump ATPase activity.

CFLP mice were

whole body

irradiated with

square-wave

modulated (16 Hz)

AnCW 2,450-MHz

or in vivo The experimental results showed that there is a MW Thus, it was concluded that a MW nn nn nn ↓+ (latency and ↓+ (latency and

experiment was effect on the SEP response of the nervous effect takes place, whichdecreases amplitude of the SEP amplitude of the SEP

amplitude and latency of the conducted on the system after a long period of irradiation, and the latency and amplitude of the response) response)

somatosensory evoked potentials nervous system of that these variations are reversible. Computations SEP response, and that the effect

(SEP) in the cortex anesthetized, of power deposition and of a bioheat equation, as a is of thermal origin. Nonthermal ↑+ (temperature ↑+ (temperature

spinal changes of the

for yes yes EXP NES in vivo New Zealand no -/- function of MW irradiation duration, revealed a nn effects were not observed. increase of the spinal increase of the spinal

cord neurological system

variation of the cerebral activity albino rabbits, temperature increase of the spinal cord for long cord; 16 min, 1W or cord; 15 min, 2W)

from somatosensory stimulation weighing about 3.5 pulsed irradiation during 15 min under an 30 sec, 2W)

(with an electrode) kg each, to incident power of 2 W; for continuous irradiation

observe the during 30 sec under an incident power of 2 W;

somatosensory and for continuous irradiation during 16 min

The authors The 3 types of microwave radiation produced The authors concluded that low- nn sham-exposure nn ↑++ (time out ↑+ (time out amplification (cw)

examined the changes in response rates on the multi FR DRL level microwave radiation can responses; 2.45 responses; 2.8 and

effects of low-level schedule. Responding on the FR schedule (which produce behavioral changes in MHz, 7 mW/cm2) 9.6 MHz)

microwave varied at baseline from 1.40 to 2.70 responses/sec) animals trained to respond on

radiation on the was disrupted after irradiation, leading to a marked multiple reinforcement schedules.

behavior of rats decrease in the overall response rate. Responding Generally, the low rates of ↓+ (responding on ↓++ (responding on amplification (pw)

trained to respond on the DRL schedule (which varied from 0.06 to responding produced by the DRL the FR schedule) the FR schedule; 2.86

in a task involving 0.08 response/sec at baseline) was increased. The schedule increased after GHz, 20 mW/cm2)

response rate (fixed intervall multiple schedules percentage increase over control levels (up to irradiation, the high rates of ↑++ (responding on

nn nn nn EXP BEH in vivo of reinforcement. behaviour -/- yes nn responding on the FR schedule ↑+ (responding on the DRL schedule;

schedule of food reinforcement) approximately 130%) was most evident at the

Four highest exposure levels for S-band pulsed and X- decreased, and the number of the DRL schedule) 2.86 GHz)

experimentally band radiation. The number of responses that responses during the time-out ↑+++ (responding on

naive male occurred during the time-out period was also period increased after irradiation. the DRL schedule; 2.9

Sprague Dawley increased after irradiation. More detailed analysis of These results also show that not GHz)

rats, 60 the response data on the DRL schedule showed that only do low levels of microwave

days old at the exposure to 9,600-Hz radiation appeared to irradiation produce effects on the

start of the study, increase DRL response rates above control values central nervous system, as

were used in at lower dose rates than the other 2 types of evidenced by behavioral changes,

experimentsof low-

The effects where radiation. The largest increase in response rates

Alterations of normal performance were more but the changes are influenced by

It is concluded that under the nn nn nn ´- ↕+ (alterations of change (pw)

power-density pronounced after a 30-min exposure to the PW conditions explored in the present normal performance;

pulsed-wave (PW) field than to the CW field. The rate of emission of study behavior is more sensitive to 10 and 15 mW/cm2)

and continuous appropriately timed responses declined after pulsed fields than to continuous

wave (CW) exposure to PW at 10 and 15 mW/cm2, whereas fields at the same power levels,

2.8-GHz exposure at the same power levels to the CW field and such differential sensitivity

microwave (MW) did not consistently affect the rate of responding. must be considered in analyzing

irradiation on Change in performance associated with MW the biological effects of MW

response time in conditioned behavior in rodents exposure was not necessarily related to a general exposure.

nn nn nn EXP BEH in vivo were behaviour -/- yes nn

behavior decline in responding; in some instances, increases

investigated. Four in overall rates of responding were observed.

240-day-old male

albino rats,

weighing 320-330

g, were

conditioned by a

complex

reinforcement

schedule that

Analgesic effects Pulp irritation induced jaw movement, respiratory

of local microwave rhythm drastically decreased and became unstable.

irradiation of the Conventional acupuncture treatment restored the

"He-Gu" respiration rate from 86 +/- 28 cycles/min to 182 +/-

acupuncture 40 cycles/min, significantly decreased its instability,

point and its The authors contended that the

and weakened jaw movement. MW radiation in

dependence upon thermal effect of intense radiation

the power range of 1-20 mW weakened jaw

impaired the

radiation intensity movement and decreased respiratory rhythm /control acupunctur: ↓+

specific analgesic response.

indices of pain: respiration rate, jaw SEN; and modulation changes of the instability to the same extent as conventional (acupuncture)/ pre- (respiration rate, ↓+ (jaw movement at ↓+ (jaw movement at

nn nn yes EXP in vivo were no -/- nn Mechanisms of the microwave nn

movement VNS neurological system acupuncture. The analgesic effect of "microwave exposure (pulp its instability, jaw low power densities) low power densities)

studied in rabbits. effect in the context of the role of

acupuncture" strongly depended on output power irradiation) movement)

Respiration rate acupuncture points in control of

(less pronounced as output power increased) and

and jaw movement biological functions are being

did not depend on the modulation regimes. In

served as indices of investigated further.

contrast with conventional acupuncture, neither

pain severity during kind of microwave treatment restored the

a 10-min direct respiration rate.

irritation of a tooth

pulp by a 50-Hz,

4- to 24-uA electric

The authors No evidence that EMF exposure either at night or in

investigated the the afternoon affected the behavior of the animals.

effects of high The experiments were conducted using

frequency simultaneous exposure and sham exposure. These

microwaves on experiments showed no significant exposure-

pineal In one of the

related effects on pineal NAT activity or serum

functions in rats experiments, The authors concluded that CW

pineal melatonin concentrations in either the rats or

and hamsters. nocturnal NAT activity 900-MHz EMFs or 917-MHz EMFs

functions: serotonin hamsters. No significant exposure-related ´- (pineal NAT ´- (pineal NAT

Sprague-Dawley was slightly higher in pulsed at 217 Hz under the ´- (pineal NAT activity,

N-acetyl-transferase (NAT); END; in vivo -> changes of the changes in synaptic ribbon profile numbers activity, serum activity, serum

nn nn nn EXP and Dark-Agouti no -/- exposed rats than in conditions used in these nn sham-exposure serum melatonin

Pineal synaptic ribbon profile MEL vitro; in vivo endocrine system were detected. melatonin melatonin

rats and controls, but the experiments have no short-term concentrations)

numbers; concentrations) concentrations)

Djungarian difference was effects on the mammalian pineal

melatonin

hamsters were not statistically gland.

exposed or sham significant.

exposed to CW

900-MHz or PW

900-MHz

microwaves pulsed

at 217 Hz for 15





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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn



yes athermal









yes nn









yes thermal









nn nn









nn nn









yes nn









nn nn









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=





5 10 minutes

4;

intervals

16

(1 min on, 1

THE ELECTRICAL ACTIVITY min off, 1min

1 min

OF SYMMETRICAL AREAS on,…)

Vorob'ev, V. V.; Fiziol Zh Im I 4Hz

OF THE RAT CEREBRAL circular antenna

Konovalov, V. F.; Russian Acad. M 1 min off organ

153 Vorob'ev, V. V. Russia

Inst. of Cell Biophysics of Russian Acad. Sciences, Pushchino, Moscow Region, Russia 0.945

1994 CORTEX DURING THE USE 0.945 none 4 20000 20000 pulsed nn 0.1 nn cw = pw above nn positioned at the top of the nn (3 intervals acute intermittent 0 rat nn 8 whole body

Gorelkova, T. F.; Sciences Sechenova 1 min 16 (nervous)

OF cage without

Gal'chenko, A. A. 80(12) Hz

A LOW-INTENSITY UHF exposure, 2

1 min off

FIELD intervals with

1 min 4

exposure)

Hz

….









AIL-type 125-microwave

Wachtel, H.; EFFECTS OF LOW- source,

Ann N Y 1,5 2,45 1000 - 20) directional coupler, and the (neuron) (nervous)

Joines, W. ISOLATED NEURONS stripline









National Inst. nerves

McRee, D. I.; PULSE MW EFFECTS ON Radiat Res waveguide part: histological cut

155 Wachtel, H. Natl. Inst. Environmental Health Sciences, Research Triangle Park, NC

Environmental USA 1982 2.45 2.45 none 50 50 10 10 pulsed nn nn 10 10 cw = pw above nn nn nn nn nn 0 (frog, nn nn

Wachtel, H. NERVE VITALITY 91(1) exposure system sciatic nerve (nervous)

Health Sciences Rana-pipiens)









head of the animal in a

waveguide,

BLOOD-BRAIN BARRIER

design as by Oscar and

Environmental PERMEATION IN THE RAT Bioelectro- Hawkins rat

Ward, T. R.; below / part: nervous

156 Ward, T. R. USA

MD-74, Environmental Protection Agency, Research Triangle Park, NC 27711

Protection 1985 DURING EXPOSURE TO magnetics 1.7 1.7 none 1000 1000 0.5 0.5 pulsed nn 0.03 - 1.0 0,1 / 200 cw = pw nn near-field 30 minutes acute continuous 0 (Sprague-Dawley, male nn

Ali, J. S. close to (Brain Res 126(2):281-93, head (BBB)

Agency LOW-POWER 1.7-GHz MW 6(2) mature)

1977;

RADIATION.

BENER volume II(2):

Abstract No. 5127)









model 299

model 299

standard gain

standard gain

wave line horn

wave line

antenna

horn antenna

with a S-band

with a S-band

waveguide

waveguide

Weiter, J. J.; ASCORBIC ACID CHANGES coupled to a lens

coupled to a

Finch, E. D.; Naval Medical IN CULTURED RABBIT Ann N Y 2,45 2,86 Raytheon nn (rabbit part: organ

157 Weiter, J. J. USA

Environmental Biosciences Dept., Naval Medical Res. Inst., Bethesda, MD 20014

1975 none 500 500 1 1 pulsed nn 0-250 nn nn nn nn nn Litton 10 minutes acute continuous 0 nn nn

Schulz, W.; Res. Inst. LENSES AFTER MW Acad Sci 247 (cw) (pw) model 4J31 (far-field) New Zealand, lens (sensoric)

Industries

Frattali, V. IRRADIATION magnetron white, adult)

model L5001

driven by a

magnetron

Manson

Laboratories

model 275

pulse tube

modulator



100 -

900



(The

energy

dosage

is histological cut

regulated (thermo-regulatory

Biomed Tech by

Wildervanck, rabbit; part: (heating pattern,

158 Wildervanck, A. none Jousterweg 4, Netherlands

HASKERHORNE [Fr], 9350, Netherlands

1978 PULSED MW-DIATHERMY (Berlin) 2.45 2.45 none 100 60 60 pulsed nn nn nn nn nn nn Diatron-1500 Diatron-1500 nn 20 minutes acute nn 0 nn nn

A. varying dog gluteal muscle temperature elevation,

23(7/8) the pearl chain

number formation)

of

pulses

over

eight dial

settings

from

ALTERATIONS IN ACTIVITY 100-900

AT AUDITORY NUCLEI OF

THE RAT INDUCED BY

EXPOSURE TO MIW

Wilson, B. S.;

RADIATION:

Zook, J. M.; Research Brain Res 0,918 2,45 2,5; rat 7 (exposed)

159 Wilson, B. S. USA

Center Technology Applications, Research Triangle Inst., Research Triangle Park, NC 27709

1980 AUTORADIOGRAPHIC none 10 10 20 20 pulsed nn 2,5 / 12500 nn cw ≥ pw above nn nn nn nn nn nn 0 nn whole body sensoric

Joines, W. T.; Triangle Inst. 187(2) (CW) (PW) 10 (Sprague-Dawley) 4 (control)

EVIDENCE USING [14C]-

Casseday, J. H.

DEOXY-D-GLUCOSE









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



The effects of The first experimental periods, which were without nn The authors suggested that pre-exposure experimental ↕+ (electrical activity ↕+ (electrical activity change of hemisphere

exposure to low- irradiation, revealed an asymmetry in the these microwave effects could periods without changes in the left changes in the right

intensity UHF frequency spectra of the electrical activity in the result from alterations of the irradiation hemisphere) hemisphere)

radiation on the left brain neurochemical status, revealed an

lateral and right hemispheres. The cortex of the left which, in turn, could arise from asymmetry in the

asymmetry of the hemisphere demonstrated higher amplitude rhythms changes in the blood-brain frequency spectra

cortical in the 10-30 Hz band, and lower amplitude rhythms barrier function or in the of the electrical

lateral electroencephalogr in the 1.5-4 Hz band compared to the right sensitivity of neuromediator activity in the left

asymmetry of the cortical aphic pattern was changes of the hemisphere. Microwave irradiation virtually receptors. and right

nn nn nn EXP CNS in situ assessed in -/- yes nn hemispheres.

electroencephalographic pattern; neurological system eliminated the frequency asymmetry in the lower

Electrocorticograms rats. Artifact-free frequency band, and decreased it in the higher

cortical electrodes frequency band. After cessation of exposure, the

made of a frequency asymmetry was partially restored.

conductive carbon Analysis of the frequency spectra during the first 10

material were sec of exposure established that the CW field

chronically caused electrical activity changes in the

implanted in the left hemisphere, while pulse-modulated fields

left and right induced changes in the right hemisphere. The

hemispheres of 8

The authors Changes in the were statistically were often and

described effects magnitude of ISIsignificant (t-seen The authors concluded that they

summarized their during irradiation at microwave intensities of detected reproducible microwave-

research less than 5 mW/cm2. In 4 cases were the induced effects

examining the thresholds for ISIs changes above 20 mW/cm2 and on firing patterns at power levels

effects of low- in 10 cases- below 10 mW/cm3. Effects on the below 10 mW/cm2. Depending on

intensity interburst intervals (IBIs) occured in 7 pacemaker which head model is used, these

microwaves on cells below 10 mW/cm2 in 3 cases. No significant power levels correspond to power

isolated marine differences between CW and PW were seen in that might be absorbed by cortical

firing patterns: interspike intervals gastropod ganglia the effects on ISI. Temperature control neurons in a person exposed to a sham-exposure/

yes nn yes EXP SIG in vitro neurons. Ganglia membrane function no -/- nn "safe" free-field microwave nn ´- ↕+ (ISIs) ↕+ (ISIs)

(ISIs) and interburst intervals (IBIs) experiments indicated that, in most cases, control (heating)

isolated increasing the temperature produced effects on intensity of anywhere from 10 to 1

from Aplysia were the ISIs that were approximately equivalent to mW/cm2. Whether or not these

used in microwave irradiation at 20 mW/cm2 or greater. effects can be considered harmful

experiments where In a few cases, unexpected effects occurred. For cannot be determined, but it

they were exposed example, irradiation of a neuron with 2.45-GHz appears

to 1.5- or radiation at a Po of 0.5 W caused complete almost certain that the effects

2.45-GHz cessation of firing, whereas heating in the same would disrupt ongoing information

microwave temperature range (21.5-22.5 C) caused an processes if they were to occur in

radiation at power

The effects of increase in firing rate. Experiments with MW effects

In all cases a significant decrease occurred in an intact nervous system.

pulsed microwave the

(MW) radiation on survival time of the exposed nerves, as

the vitality of frog compared with the unexposed nerves. However,

sciatic nerves were It is suggested that the MW effect

the magnitude of this effect was essentially the

investigated and on nerve

same in all three cases of exposure and was also

compared with vitality may result from an

comparable with the effect seen earlier with CW MW

effects of interference with long-term

radiation of equivalent SAR.

continuous-wave regulatory processes (such as

survival time of the exposed nerves nn nn nn EXP CEF in vitro (CW) MW cell vitality no -/- nn interfering with maintenance of nn sham-exposure ´- (survival time) ↓++ (survival time) ↓++ (survival time)

radiation. Isolated adequate ionic concentration

sciatic nerves of gradient across the membrane)

frogs (Rana rather than interference with the

pipiens) were mechanism for action potential

exposed to 2.45- firing.

GHz pulse-MW

radiation in a

waveguide

exposure system.

The authors Small (0.22 C maximum) but statistically

conducted a study significant increases in temperature were found

designed to follow in two brain regions of exposed animals, the

up previous work midbrain and stratum. No change in uptake of either

by Oscar tracer was found in any of the brain regions as

and Hawkins The authors conclude, on the

compared with those of sham-exposed animals,

(Brain Res basis of their results and other

indicating that there were no changes in

126(2):281-93, recent reports in the literature, that

permeation.

1977; BENER morphological and there is little evidence that low-level

permeability of BBB (radioactivity in in vivo -> ´- (BBB

yes brain yes EXP BBB volume II(2): pathological no -/- nn microwave irradiation affects the nn sham-exposure ´- (BBB permeability) ´- (BBB permeability)

brain) vitro permeability)

Abstract changes blood-brain barrier, although

No. 5127) who possible changes in blood flow at

reported dramatic these low power levels cannot be

increases in ruled out.

permeation of the

blood-brain

barrier as

measured by

mannitol and inulin

The authors Exposure to CW microwave radiation for 10 min at The authors concluded that nn nn nn ↓+ (AA concentration) ↓+ (AA concentration)

examined the power densities of 0 to 250 mW/cm2 caused a irradiation of rabbit lens ↑+ (opacification, if ↑+ (opacification, if

effect of linear power density-related decrease in lens AA preparations with CW or pulsed AA concentration AA concentration was

AA content (AA + microwave was pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=









Research

MECHANISMS AND

Triangle Inst.,

PHYSIOLOGIC J

Wilson, B. S.; Research 10: 2,5;

USA SIGNIFICANCE OF Durham,Bioelectricity

e Program Office, Research Triangle Inst., Research Triangle Park, NC 27709 (B.S.W.);Dept. of Electrical Engineering, Duke Univ.,MW

160 Wilson, B. S. 1985 NC 27709 (W.T.J.)

2.45 2.45 none nn nn 10 pulsed nn nn nn nn above nn nn nn nn nn nn 0 rat nn nn nn sensoric

Joines, W. T. Triangle Park; 20 10

ACTION ON THE AUDITORY 4(2)

Duke Univ.,

SYSTEM

Durham









Univ.of Naples waveguide

Federico II; CYTOGENETIC DAMAGE IN GSM-like 16

d'Ambrosio, G.; 0,0623

Interuniversity HUMAN LYMPHOCYTES Bioelectro- (GMSK phase Rohde Schwarz SME 03 cell (8 males)

Massa, R.; (cw); mobile female (?), cell: cell culture

161 Zeni, O. Centre for and

Dept. of ElectronicItaly Telecommunication Engineering, Univ. of Naples Federico II, Via Claudio,21, 80125 Naples, Italy, e-mail: gdambros@unina.it nn

2002 FOLLOWING GMSK PHASE magnetics 1.748 1.748 none nn nn nn (RR/G.d., R.M.); Interuniversity Centre forInteraction Between Electromagnetic Fields and Biosystems, Naples, Italy (G.d., R.M., M.R.S., O.Z.);Natl. Res. Council a IREA, Naples, Italy (M.R.S., O.Z.)

modulated nn 1,17 - 3,93 cw = pw close to signal source with - built-in nn 15 minutes acute continuous 1 (human

Rosaria Scarfi, M.; 0,0594 telephone male lymphocyte (immune)

Interaction MODULATED MW 23(1) microwave GMSK modulation mode, lymphocytes) > 500

Zeni, O. (pw)

Between EMF EXPOSURE radiation) coupled to a TWT amplifier lymphocytes

and Biosystems (Varian VZS 6951 K2 BDEK)









Zeni, O.; CNR-Inst. for

GSM signal

Chiavoni, A. S.; Electromagnetic LACK OF GENOTOXIC

produced by a human cell culture:

Sannino, A.; Sensing of EFFECTS (MICRONUCLEUS CW signal

Radiat Res 0,2; below / modified 24; 44: 72 (healthy volunteers, 12 female, 8 peripheral- cell culture

162 Zeni, O. Antolini, A.; Environment Italy

ICEmB at CNR-Inst. for Electromagnetic Sensing of Environment (IREA), via Diocleziano, 0.9

2003 INDUCTION) IN HUMAN 328-80124Napoli,none e-mail: scarfi.mr@irea.cnr.it (RR/M.R.S., O.Z., A.S.); TILab, viann Reiss Romoli274, 10148 Torino, Italy (A.S.C., A.A., D.F.); ICEmB cwDept. of Physics, Univ. of Bologna, VialeBerti Pichat 6/2, 40127 Bologna, Italy (F.B.)

0.925 Italy, nn nn nn nn GSM-like G. nn 1.6 at ≥ pw nn generator; near-field temporary intermittent 1 20

160(2) 1,6 close to commercial hours age 32 +/- 9 yr male blood lympho- (immune)

Forigo, D.; (IREA); LYMPHOCYTES EXPOSED TEM cell

cellular phone; lymphocytes) cytes

Bersani, F.; TILab; IN VITRO TO 900 MHz EMF

TEM cell

Scarfi, M. R. Univ. of Bologna









0,8 - 1,2 0,8 - 1,2

THE EFFECTS OF 860 MHz averaged averaged

RF RADIATION ON THE over the over the

George Motorola Integrated AC76

Zook, B. C.; INDUCTION OR Radiat Res brain, brain, 6 hours/day rat organ

163 Zook, B. C. Washington USA

George Washington Univ., Ross Hall, B-12, 2300 I St., N.W., Washington, DC 20037 (RR/B.C.Z.);Depts. of none

2001 0.860 0.860 Pathology11.1 of Epidemiology and Biostatistics, George Washington1

and 11.1 15000 15000 pulsed Univ., Washington, nn

DC20037 cw = pw below nn near-field chronic intermittent 0 nn 900 whole body

Simmens, S. J. PROMOTION OF BRAIN 155(4) 0,27-0,42 0,27-0,42 Radio Services source 22 months (Sprague-Dawley) (nervous)

Univ.

TUMORS AND OTHER averaged averaged

NEOPLASMS IN RATS. over the over the

whole body whole body









* Sorting-Name technical application

To identify

similar studies,

the table is

sorted with the

nn

name of this

column.

Sometimes

this name is

not the first in technique for remote determination of breathing frequ. in unrestrained animals using RF EM waves

dielectric measurement

electronical weapon



industrial heating



medical application

medical heating

microscopic RF dosimetry

microwave killing

microwave oven

microwave thawing

mobile telephone

radar System of Body

in vivo endocrine

neuro-endocrine



reproductive

sensoric



thermo-regulatory

immune

muscle-skeleton

cardio-vascular

respiratory

haematopoetic

nervous

digestive

whole organism



in vitro biological molecules

cell-free

cell organelles

cell Example: cell (nervous)



cell culture /

Forschungsgemeinschaft Funk e.V.

Seite 70 von 100

cell culture (organic)

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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)



Microwave hearing The MWAS spectrum of the thresholds for the The authors concluded that

or responses of the responses to the microwave pulses spanned the CF thermoelastic expansion of fluids

auditory system to range of 0.3 to 30 kHz. The frequency content of and structures within the inner ear

microwave pulses the MWAS spectrum could be expressed as a is the major mechanism by which

(perceived as sinusoidal function of the form sin(x)/x. This was auditory stimuli are produced by

clicks) is one of the taken as evidence in support of the thermoelastic microwave pulses. The frequency

most widely expansion mechanism. In the rat experiment, spectra of these stimuli are ↑+ (level of metabolic

microwave induced auditory stimuli studied and changes in the pattern of dGlu uptake by the inferior indistinguishable from the spectra activity, dGlu uptake, changes in the pattern

(MWAS): metabolic activity induced accepted colliculus indicated that the MWAS spectrum for the of rectangular pulses of the same in nuclei in the of dGlu uptake by the

EOE; changes of the

in the inferior colliculus; yes cochlea yes EXP in vivo effects of low- no -/- microwave pulses was very broad and was similar to nn duration as the microwave pulses. nn nn nn ascending auditory inferior colliculus;

TMP neurological system

uptake of carbon-14 (14C-) tagged power nonionizing that induced by the acoustic clicks and noise. A The observed behavioral effects of pathway; increase of thermoelastic

2-deoxy-D-glucose (dGlu) radiation on model based on the thermoelastic hypothesis microwave exposure can be intracochlear expansion

biological systems. indicated that the area in the MWAS spectrum explained on the basis of temperature)

Early wherein microwave pulses would be expected to intracochlear heating. Very small

studies indicated produce effective auditory stimuli would be bounded shifts in inner ear temperature, for

that these effects by the upper limit of hearing (31 kHz in the cat), the example, can produce large

did not involve maximum level of peak power, and the individual changes in an animal's sensitivity

electrophonic spectral curves for each pulse duration as described and suprathreshold responses to

heating

The authors by the function sin(x)/x.

Exposure to CW or GMSK phase modulated environmental sounds.

The authors concluded that, under nn control ´- ´- (CBPI) ´- (CBPI)

examined radiation did not significantly affect the CBPI in their experimental conditions, CW ´- (Micronuclei ↑+ (Micronuclei increase (pw)

cell cycle progression and cytogenetic frequency) frequency)

any experiment (mean CBPIs were 1.87 +/- 1.748-GHz radiation does not

chromosome damage (Micronuclei damage induced in 0.055 in unexposed cultures, 1.83 +/- 0.08 in CW affect MN frequency, whereas

frequency) human exposed cultures, and 1.99 +/- 0.063 in GMSK irradiation with GMSK phase

lymphocytes by exposed cultures). Exposure to CW radiation only modulated radiation increases

Cytotoxicity and changes in cell Gaussian minimum did not significantly alter MN frequency, but the MN frequency. They noted

proliferation shift keying exposure to GMSK phase modulated radiation that the intensity level used in their

(by classifying 500 lymphocytes (GMSK) phase

external significantly increased the group mean MN experiments was substantially

according to their number of yes no EXP GEN in vitro modulated genotoxicity -/- yes nn

medium frequency (0.89 +/- 0.01%, p indication that RF irradiation altered the incidence of fatal

body weight; nn nn nn EXP TUM exposure cancer no -/-

vitro incidence of the tumors at any of these sites. brain tumors than

incidence of brain tumors to RF radiation of sham-exposed rats

the type emitted by and the cage controls.

cellular phones Neither of these

induced or represented a

promoted statistically significant

brain tumors or elevated risk.

other

malignancies.

Fifteen groups of





Class Type of study

nn







nn nothing named









experimentelle biologisch-medizinische Studien in vivo

EXP

in vivo probands

in vivo patients

in vitro



in vivo -> vitro

in vitro; in vivo

in situ

epidemiology

chemical model system

physical model system

literature









ervous)





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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









nn thermal









nn nn

(athermal)









nn nn









nn nn









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Nu Author Publication Exposure Test-Objects

mbe

Proximity Number Parts of

Stu Sorting- Pulse repetition Pulse Intensit Powerflux-density Technical Exposure device Kind

Names Affilation Address Country Year Title Journal Frequency Modulation Specific absorption rate (SAR) to Duration of exposure Human Biological object Gender of organism System of body

dy Name * frequency width y (PFD) application (device to generate the field) of exp.

SAR objects exposed

avarage energy threshold

clearly acc. acute=

Abbreviations: CW- PW- CW- PW- deposit CW- PW- pw above intermittent (type, age) cell list below

MW = Microwave(s) n.n. chron= male, nn

[mW/cm2] [W/Kg] cw ≤ pw (ref. 0,08 component;

PW = Pulsed Wave near life

cw ≥ pw W/kg / model

RF = Radiofrequency common common (SAR- or PFD- common mark means: time

mark means: mark means: value)

2 W/kg) not differently mentioned

not differently not differently multi=

organ



histological cut



in situ cell Example: cell (nervous)



organ

chemical model system chemical model

physical model system physical model system









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Measurement Classification Objectives and Results



Biological

Measured Temperature Temperatu Type of

Class Category Abstract endpoint Difference between CW and PW effects Biological effects of CW and PW exposure

parameters control re effects? study

of view



kind of effect

yes (caused by Tendencies

no yes sham-exposure cw vs. pw or vs. control

fix Point of irridation) acc. Kind of difference (without statistical

acc. The authors conclude/ Action-hypothesis / shelf control / ↑+; ↑++; ↓+; ↓++; ↕+; ↕++ ("changes"); ´-; nn

=contro measure pull-down- significance)

list below suggest… (if mentioned) pre-exposure/

lled ment menu

no control/ n.n.

nn yes; 104 59

sham/control cw pw effect categories

no 63.8% 36.2% (uncompleteley simplified)









ervous)









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Thermal

nature of

Reversibility

effect

of effect

(if

mentioned)



yes/no/nn









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number of

technical application publications

technique for remote determination of

8

breathing frequ. in unrestrained 0

animals using RF EM waves

dielectric measurement 0

electronical weapon 0 7

industrial heating 0

medical application 6

medical heating 0

microscopic RF dosimetry 0 6

microwave killing 1

microwave oven 0

microwave thawing 0

mobile telephone 7 5

radar 3

nn 146

163 4





3





2





1





0

measurement

determination









electronical

technique for









dielectric

remote



of…

electronical

weapon





industrial

heating





medical

application





medical

heating





microscopic

RF dosimetry





microwave

killing





microwave

oven

Number of publications per technical application









microwave

thawing

mobile

telephone







radar

number of

year

publications

2006 2

2005 8

2004 5 14

2003 6

2002 8

2001 12

2000 2 12

1999 5

1998 0

1997 8

1996 8 10

1995 2

1994 7

1993 4

1992 4

1991 3

8

1990 3

1989 3

1988 7

1987 4 6

1986 3

1985 8

1984 5

1983 3 4

1982 8

1981 1

1980 7

1979 3 2

1978 7

1977 3

1976 2

1975 8

1974 1

0

1973 0 1960 1965 1970 1975

1972 1

1971 0

1970 0

1969 1

1968 0

1967 1

1966 0

1965 0

1964 0

1963 0

1962 0

1961 0 14

1960 0

summa 163 12



10



8



6

4



2



0

Number of publications p.a.









1975 1980 1985 1990 1995 2000

Year









Number of publications p.a.

2000 2005

number of

country

publications

Argentina 0

Australia 1

Austria 1 80

Belarus 2

Belgium 2

Brazil 0

Bulgaria 0

70

Canada 5

China 1

Costa Rica 0 60

Czech Republic 0

Denmark 0

Finland 3 50

France 5

Germany 9

Greece 1 40

Hungary 5

India 1

Israel 0 30

Italy 7

Japan 2

Netherlands 2

New Zealand 0

20

Poland 5

Romania 0

Russia 12 10

Saudi Arabia 0

Slovakia 0

Slovenia 0 0







Czech…

South-Korea 0

Brazil

Austria









Finland

Argentina









China









France

Belgium







Canada





Costa Rica





Denmark

Australia









Bulgaria

Belarus









Spain 0

Sweden 9

Switzerland 2

Turkey 0

UK 2

Ukraine 2

USA 75

USSR 8

Yugoslavia 1

nn 0

163

France

Germany

Greece

Hungary

India

Israel

Italy

Japan

Netherlands

New Zealand

Poland

Romania

Russia

Saudi Arabia

Number of publications per country









Slovakia

Slovenia

South-Korea

Spain

Sweden

Switzerland

Turkey

UK

Ukraine

Ukraine

USA

USSR

Yugoslavia

number number frequ. number number

frequ.

of publ. of publ. up to of publ. of publ.

[GHz]

min. max. [GHz] min. max.

0.0001 1 0 0.1 3 0 minimal frequency

0.0005 0 0 0.2 1 0 60

0.001 0 0 0.4 4 0

0.01 1 0 0.6 7 5

0.01312 0 0 0.8 0 0

0.05 1 0 1 47 45

0.07 0 0 1.2 3 2 50

0.147 0 0 1.4 7 8

0.18 1 0 1.6 3 1

0.22 1 0 1.8 5 7

0.27 2 0 2 2 2

0.35 1 0 2.1 1 1

0.425 1 1 2.2 0 0 40

0.46 2 2 2.3 0 0

0.5 1 0 2.4 2 2

0.546 1 0 2.5 47 41

0.591 1 1 2.6 0 0

0.6 1 1 2.7 0 0 30

0.835 1 0 2.8 7 9

0.83562 7 0 2.9 0 1

0.84 1 1 3 3 8

0.84774 0 7 4 0 1

0.86 1 1 5 1 1

0.872 1 0 6 2 4 20

0.88 2 1 7 1 1

0.89 1 1 8 0 0

0.9 17 15 9 2 1

0.902 2 2 10 3 7

0.915 10 12 > 10 9 10 10

0.925 0 1 nn 5 5

0.917 0 2 mobile phone 2 1

0.918 2 1 163 163

0.945 1 1

1 1 1

0

1.05 1 0

0.2



0.4







0.8







1.2

0.1









0.6







1



1.2 2 2

1.22 1 1

1.25 2 2

1.3 4 5

1.5 2 0

1.6 1 1

1.7 1 1

1.748 1 1

1.8 3 5

1.9 2 2

2.06 1 1

2.375 2 1

2.39 0 1

2.4 0 0

2.42 1 0

2.45 46 41

2.75 0 3

2.8 7 6

2.86 0 1

2.88 0 0

2.95 1 1

2.97 0 1

3 2 6

3.1 0 1

4.2 1 1

5.5 1 1

5.6 1 3

5.8 0 0

6.45 1 1

7.1 0 0

8.4 1 0

8.42 1 1

9 0 0

9.3 3 3

9.4 0 1

9.6 0 3

9.7 0 0

10 0 0

10.4 0 0

10.7 0 1

12.4 0 1

15 0 1

17 0 1

27.12 0 0

37.5 0 0

40 1 0

42.19 0 0

42.2 1 1

53 0 0

54 1 0

72.2 2 1

mobile phone 2 1

78 2

76 1 1

nn 5 5

163 163

Number of publications per frequency

minimal frequency in the study

1.4 maximal frequency in the study

1.6









2.2







2.4



2.5







2.7







2.9

1.2









1.8



2



2.1







2.3









2.6







2.8









4



5







7

3









6









(up to) Frequency [GHz]

8



9



10



> 10

frequ.

frequ. number number

up to

[Hz] of publ. of publ.

[Hz]

0.00001 1 1 20

0.001 1

0.1 0 5 20

0.167 0 10 28 60

0.5 7 50 55

1 11 100 19

1.7 0 500 49

2 0 1000 29

2.5 4 5000 4 50

3 1 10000 3

4 12 upper 1

5 3 nn 47

6 7 275

7 1 MEHRFACHNENNUNGEN MÖGLICH!

40

8 10

9 2

10 8

11 1

11.1 1

30

12 1

13 2

16 22

17 1

21 1

22 2

20

25 2

30 1

32 4

40 1

50 16 10

60 2

75 2

80 1

83 0

100 14 0

110 1 1 5

138 2

200 3

217 19

250 5

300 1

350 0

370 1

400 1

413 1

500 15

555 1

600 2

700 1

710 1

769 1

935 1

1000 22

1200 1

2000 1

5000 2

6000 1

10000 2

30000 1

1E+12 0

nn 47

MEHRFACHN

ENNUNGEN

275 MÖGLICH!

Number of publications per

pulse repetition frequency (min.)









5 10 50 100 500 1000 5000 10000

(up to) frequency [Hz]

10000 upper nn

width

width number number

[µs] of publ.

up to

of publ. Number of public

[µs]

0.01 1 1 25

0.1 1 5 24 80

0.15 1 10 14

0.5 7 50 6

1 15 100 2

1.2 1 500 2 70

1.3 2 1000 8

1.5 1 5000 0

2 13 10000 4

2.7 2 50000 4 60

3 2 100000 0

5 3 500000 0

6 1

50

7.1 0 1000000 0

10 14 nn 74

10.9 0 163

20 3

40

30 3

60 1

65 1

100 1 30

500 2

570 5

576 2

577 1 20

580 1

750 1

2000 1

5000 1 10

4000 3

6000 2

6670 1

6700 1 0

9200 1 1 5 10 50 100

10000 1

15000 1

20000 1

25000 2

400000 0

750000 0

1000000 0

100

Number of publications per pulse width









100 500 1000 5000 10000 50000 100000 500000



(up to) pulse width [µs]

1000000 nn


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