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									The Endocrine System

       VS 223
      Dr. Noland
      Endocrine Glands
• Secrete their product directly
  into bloodstream
• Known as “ductless” glands
           Hormones
• Act on target organs due to specific
  receptors located on the target
  plasma membrane
    Neuroendocrine Reflex
• Nerve input on the afferent end
• Hormonal input on the efferent end

• Suckling reflex
• Induced ovulation in cats, rabbits
      Endocrine Glands
• Discrete gland - Adrenal gland

• Organ – Duodenum

• Combo of Exocrine/Endocrine -
  Pancreas
   Classification of Hormones
• Peptides – chains of amino acids
       –Most hormones
• Amines – tyrosine derivatives
       –Catecholamines, T4
• Steroids – cholesterol derivatives
       –Gonadal hormones and adrenal
        cortical hormones
    Mechanisms of Action
• Hormones circulate in the
  bloodstream and bind with
  target organ cell receptors to
  affect a change in the target cell
Hydrophilic
Hormones
 Peptides and
Catecholamines
Lipophilic Hormones
 Steroids and Thyroid
Hormonal
 Action
Feedback Regulation

								
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