GENE LIST
(NOT COMPREHENSIVE)
GENE NAME PROTEIN ENCODED SOME SITES OF EXPRESSION
5-a reductase Enzyme Testis
a-6-b-1-integrin Membrane protein Egg
Acrosin Enzyme sperm
Activin Secreted molecule Vegetal pole/ Xenopus, notochord
Angiopoeitin Secreted molecule Mesenchymal cells
b1,4- Enzyme/receptor sperm
galactosyltransferase
Bicoid Transcription factor Anterior end of fly embryo
BMP2 Secreted molecule AER, endoderm
BMP4 Secreted molecule epidermal ectoderm, lateral plate mesoderm, endoderm
BMP5 Secreted molecule prechondrial mesenchyme of axial skeleton,ear
BMP7 Secreted molecule Epidermal ectoderm
c-kit Receptor tyrosine kinase Neural crest, germ cells,hematopoietic cells
c-met Receptor tyrosine kinase Myoblasts
c-ret Receptor tyrosine kinase Neural crest cells, kidney
CatSper Membrane protein sperm
Cbfa1 Transcription factor Sites of bone formation prior to ossification
Collagens extracellular matrix variety of tissues
d-Hand Transcription factor myocardium
DCC Membrane protein commissural neurons
Delta Membrane bound ligand Neural precursors
Dpp Secreted molecule Dorsal region of the Drosophila embryo
Dvb-1 (Developmental Hypothetical Protein Determined in exam
Biology 1)
E-cadherin Membrane protein pre-implantation embryo, epithelial cells
e-Hand Transcription factor myocardium
En-1 Transcription factor Ventral ectoderm
Endothelin receptor Transmembrane receptor Neural crest, and enteric neuroblasts, pharyngeal arch mesenchyme
Endothelins Secreted molecule brachial arch endothelium, aortic arch endothelium, gut endoderm
Engrailed, Wingless Transcription factors Cellular blastoderm
Erythropoietin (EPO) Secreted molecule Liver, spleen and kidney
Eve, Hairy Transcription factors Syncytial blastoderm
Fertilin Membrane protein sperm
Fgf10 Secreted molecule limb mesoderm, variety of tissues
Fgf4 Secreted molecule ICM, AER, limb
Fgf8 Secreted molecule limb, AER, variety of tissues
FGFR1,2,3 Transmembrane proteins bones, variety of tissues
Fibrillin-1 Matrix protein Cardiac cushion
Follistatin Secreted protein Pancreatic mesoderm
Fos Transcription factor Variety of tissues
GDF1 Secreted molecule Variety of tissues,including node
GDF5 Secreted molecule pre-cartilage mesenchyme of the limbs
GDNF Secreted molecule kidney,variety of tissues
GFRa Transcription factor kidney, variety of tissues
Hedgehog (hh) secreted molecule Cellular blastoderm
HNF3b Transcription factor Node, notochord, floorplate, endoderm
Hox genes (A-D), 1-13 Transcription factors variety of tissues
Hunchback Transcription factors Syncytial blastoderm (high level anteriorly, low to absent levels posteriorly)
Kruppel Transcription factors Syncytial blastoderm (in the region about halfway thru the egg length from
Knirps Transcription factors the anterior end)
Syncytial blastoderm (some in the anterior end, more in the region 2/3 the
Giant Transcription factors Syncytial blastoderm (in the the anterior end)
way thru the egg length fromregion 1/4 and 3/4 the way thru the egg length
Tailess Transcription factors from the blastoderm
Syncytialanterior end)
I-mf Transcription factor Sclerotome
Indian hedgehog (ihh) Secreted molecule Chondrocytes
Indoleamine 2,3- Enzyme trophoblasts
dioxygenase (IDO)
LacZ Enzyme nuclear or cytoplasmic
LIF (leukemia inhibitory Secreted molecule Endometrium
factor)
Lmx-1 Transcription factor Dorsal mesenchyme
Mef2C Transcription factor Myocardium, myoblasts, other tissues
Mfg-1 (My Favorite Hypothetical Protein Determined in exam
Gene-1)
GENE LIST
(NOT COMPREHENSIVE)
MRF4 Transcription factor Myoblasts that have exited the cell cycle
Mullerian Inhibitory Secreted molecule Sertoli cells
Substance (MIS)
Myf5 Transcription factor Myoblasts
Myo D Transcription factor Myoblasts
Myogenin Transcription factor Myoblasts that have exited the cell cycle
myosin VIIa cytoskeletal eye, ear
myosinII HC-A cytoskeletal variety of tissues
MyosinII HC-V cytoskeletal variety of tissues
Nanos RNA binding protein Posterior end of fly embryo
Netrin Secreted molecule neural tube
neurotrophin Secreted protein postsynaptic cells
Nkx2.5 Transcription factor Cardiac crescent
nodal Secreted molecule extraembryonic, embryonic tissues, node
Nogo Transmembrane protein oligodendrocytes
Notch Transmembrane receptor non-neuronal precursors
4-Oct Transcription factor all cells up to 8 cell stage then restricted to ICM
Otx2 Transcription factor Anterior visceral endoderm
Parathyroid related Peptide hormone perichondrium
hormone
Patched (ptc) Transmembrane receptor variety of tissues
Pax1 Transcription factor Sclerotome, limb buds, face mesenchyme, pharyngeal arches
Pax3 Transcription factor paraxial mesoderm
Pax6 Transcription factor Neural ectoderm
Phospholipase Cd4 Intracellular protein sperm
Pitx-1 Transcription factor Hindlimb
Polycystin I (PKD-1) Membrane protein uteric bud
Rhodopsin Membrane protein retina
Robo membrane protein commissural neurons
Scatter factor (SF/HGF) Secreted molecule In dermamyotome
Scr, Antp, Ubx Transcription factors Cellular blastoderm and later
Slit Secreted molecule neural tube
Smad2 Transcription factor Visceral endoderm and parts of epiblast
Smoothened (smo) Transmembrane protein Shh-responsive cells and tissues
Sonic hedgehog (shh) Secreted smolecule node, notochord, floorplate, limb bud mesenchyme, endoderm
Sox9 Transcription factor Chondrocytes, other tissues
Src tyrosine kinase Variety of tissues
SRY Transcription factor Testis
steel secreted protein variety of tissues
Tbx4, 5 Transcription factors limbs, somatic mesoderm
Testosterone Steroid Hormone Leydig cells
TGFb Secreted molecule Region of the atrioventricular and outflow tracts
TIE1 and 2 membrane protein Endothelial cells
VEGF Secreted smolecule Endoderm, mesoderm
VEGFR 1-2 Transmembrane Angioblasts blood islands/endothelial cells
vHNF-1 Transcription factor Visceral endoderm; liver
Wnt1 Secreted molecule neural tube
Wnt7a Secreted molecule limb ectoderm
ZP1,ZP2, ZP3 glycoproteins egg