Cell Signaling Diseases Project

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					                              Cell Signaling Diseases Project
Each pair of individuals will choose from the list below. No topics may be chosen twice. I
suggest that when you begin your research you Google the disease and cell signaling or signal
transduction. Your responsibility is to develop a poster that explains the basics of the disease
and its relationship to a faulty signal transduction pathway. Your poster must explain both the
"normal" pathway and the "faulty" pathway. Pictures and graphics are also necessary. I do not
expect you to work at the graduate level on this project but I do expect you to be able to explain,
in your own words, the basics of the mechanism and the way in which the failure of the
mechanism leads to disease.

Grading: Total Points - 60

Format - poster - 10 points
. 18" X 24" minimum
. Typed headings
. Pictures and graphics as needed
. Neat presentation - no spelling or grammatical errors

Content - 40 points
. Disease - basics only - cause and core symptoms
. Cell signaling pathway involved
o Correct mechanism
o Incorrect mechanism
o Graphics of pathway
. Current direction of research

Presentation - 10 points
. Three to Five minute presentation of poster to class
. Be able to put content into "own words" and explain poster
. No direct reading off poster

Disease Choices
Ataxia-telangiectasia (AT)
Heart Disease - Congenital Heart Disease and Cardiomyocyte hypertrophy
Kidney disease
Parkinson's disease and calcium channels
Multiple sclerosis
Pancreatic cancer
Chronic myelogenous leukemia - Chronic Myeloid leukemia - CML
Alzheimer's disease
Tuberous sclerosis
Insulin Resistance and Diabetes

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