Autism - Pipeline Review, H2 2011 by GlobalMarketsDirect

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									Autism – Pipeline Review, H2 2011




                                  Autism - Pipeline Review, H2 2011
                                                                                          Reference Code: GMDHC1345IDB

                                                                                          Publication Date: September 2011




Autism – Pipeline Review, H2 2011                                                                             GMDHC1345IDB / Pub September 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                                                 Page(1)
Autism – Pipeline Review, H2 2011



Ta b le o f Co n te n ts
Table of Contents                                                                                                     2
List of Tables                                                                                                        6
List of Figures                                                                                                       7
Introduction                                                                                                          8
     Global Markets Direct Report Coverage                                                                            8
Autism Overview                                                                                                       9
Therapeutics Development                                                                                             10
     An Overview of Pipeline Products for Autism                                                                     10
Autism Therapeutics under Development by Companies                                                                   12
Autism Therapeutics under Investigation by Universities/Institutes                                                   13
Late Stage Products                                                                                                  16
     Comparative Analysis                                                                                            16
Mid Clinical Stage Products                                                                                          17
     Comparative Analysis                                                                                            17
Early Clinical Stage Products                                                                                        18
     Comparative Analysis                                                                                            18
Discovery and Pre-Clinical Stage Products                                                                            19
     Comparative Analysis                                                                                            19
Autism Therapeutics - Products under Development by Companies                                                        20
Autism Therapeutics - Products under Investigation by Universities/Institutes                                        21
Companies Involved in Autism Therapeutics Development                                                                23
     Neuropharm Group Plc                                                                                            23
     Shenzhen Beike Biotechnology Co., Ltd.                                                                          23
     Seaside Therapeutics                                                                                            24
     Snowdon Inc.                                                                                                    24
     Curemark, LLC                                                                                                   25
     Cellceutix Pharmaceuticals, Inc.                                                                                25
Autism - Therapeutics Assessment                                                                                     26
     Assessment by Monotherapy Products                                                                              26
     Assessment by Combination Products                                                                              27
     Assessment by Route of Administration                                                                           28
     Assessment by Molecule Type                                                                                     30
Drug Profiles                                                                                                        32
     CM-AT - Drug Profile                                                                                            32
          Product Description                                                                                        32
          Mechanism of Action                                                                                        32
          R&D Progress                                                                                               32
     STX209 - Drug Profile                                                                                           33
          Product Description                                                                                        33
          Mechanism of Action                                                                                        33
          R&D Progress                                                                                               33
     Celexa - Drug Profile                                                                                           34
          Product Description                                                                                        34
          Mechanism of Action                                                                                        34
          R&D Progress                                                                                               34
     Mecamylamine - Drug Profile                                                                                     35
          Product Description                                                                                        35


Autism – Pipeline Review, H2 2011                                                         GMDHC1345IDB / Pub September 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                              Page(2)
Autism – Pipeline Review, H2 2011


          Mechanism of Action                                                                                        35
          R&D Progress                                                                                               35
     N-Acetylcysteine - Drug Profile                                                                                 36
          Product Description                                                                                        36
          Mechanism of Action                                                                                        36
          R&D Progress                                                                                               36
     Trichuris Suis Ova - Drug Profile                                                                               37
          Product Description                                                                                        37
          Mechanism of Action                                                                                        37
          R&D Progress                                                                                               37
     KM-391 - Drug Profile                                                                                           38
          Product Description                                                                                        38
          Mechanism of Action                                                                                        38
          R&D Progress                                                                                               38
     N-Acetylcysteine - Drug Profile                                                                                 39
          Product Description                                                                                        39
          Mechanism of Action                                                                                        39
          R&D Progress                                                                                               39
     Zyprexa - Drug Profile                                                                                          41
          Product Description                                                                                        41
          Mechanism of Action                                                                                        41
          R&D Progress                                                                                               41
     Fluoxetine - Drug Profile                                                                                       42
          Product Description                                                                                        42
          Mechanism of Action                                                                                        42
          R&D Progress                                                                                               42
     Olanzapine - Drug Profile                                                                                       43
          Product Description                                                                                        43
          Mechanism of Action                                                                                        43
          R&D Progress                                                                                               43
     Oxytocin - Drug Profile                                                                                         44
          Product Description                                                                                        44
          Mechanism of Action                                                                                        44
          R&D Progress                                                                                               44
     Ziprasidone - Drug Profile                                                                                      45
          Product Description                                                                                        45
          Mechanism of Action                                                                                        45
          R&D Progress                                                                                               45
     Aripiprazole - Drug Profile                                                                                     47
          Product Description                                                                                        47
          Mechanism of Action                                                                                        47
          R&D Progress                                                                                               47
     Succimer - Drug Profile                                                                                         48
          Product Description                                                                                        48
          Mechanism of Action                                                                                        48
          R&D Progress                                                                                               48
     Memantine + Risperidone - Drug Profile                                                                          49
          Product Description                                                                                        49




Autism – Pipeline Review, H2 2011                                                         GMDHC1345IDB / Pub September 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                              Page(3)
Autism – Pipeline Review, H2 2011


          Mechanism of Action                                                                                        49
          R&D Progress                                                                                               49
     Bumetanide - Drug Profile                                                                                       50
          Product Description                                                                                        50
          Mechanism of Action                                                                                        50
          R&D Progress                                                                                               50
     Tpoiramate + Risperidone - Drug Profile                                                                         51
          Product Description                                                                                        51
          Mechanism of Action                                                                                        51
          R&D Progress                                                                                               51
     Oxytocin - Drug Profile                                                                                         52
          Product Description                                                                                        52
          Mechanism of Action                                                                                        52
          R&D Progress                                                                                               52
     Pentoxifylline + Risperidone - Drug Profile                                                                     53
          Product Description                                                                                        53
          Mechanism of Action                                                                                        53
          R&D Progress                                                                                               53
     Risperidone + Celecoxib - Drug Profile                                                                          55
          Product Description                                                                                        55
          Mechanism of Action                                                                                        55
          R&D Progress                                                                                               56
     Buspirone - Drug Profile                                                                                        57
          Product Description                                                                                        57
          Mechanism of Action                                                                                        57
          R&D Progress                                                                                               57
     Sertraline - Drug Profile                                                                                       58
          Product Description                                                                                        58
          Mechanism of Action                                                                                        58
          R&D Progress                                                                                               58
     Aripiprazole - Drug Profile                                                                                     59
          Product Description                                                                                        59
          Mechanism of Action                                                                                        59
          R&D Progress                                                                                               59
     Aripiprazole + D-cycloserine - Drug Profile                                                                     60
          Product Description                                                                                        60
          Mechanism of Action                                                                                        60
          R&D Progress                                                                                               60
     Donepezil HCl - Drug Profile                                                                                    61
          Product Description                                                                                        61
          Mechanism of Action                                                                                        61
          R&D Progress                                                                                               61
     D-Cycloserine - Drug Profile                                                                                    62
          Product Description                                                                                        62
          Mechanism of Action                                                                                        62
          R&D Progress                                                                                               62
     Abilify - Drug Profile                                                                                          63
          Product Description                                                                                        63




Autism – Pipeline Review, H2 2011                                                         GMDHC1345IDB / Pub September 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                              Page(4)
Autism – Pipeline Review, H2 2011


          Mechanism of Action                                                                                                            63
          R&D Progress                                                                                                                   63
     Oxytocin - Drug Profile                                                                                                             64
          Product Description                                                                                                            64
          Mechanism of Action                                                                                                            64
          R&D Progress                                                                                                                   64
     Risperidone - Drug Profile                                                                                                          65
          Product Description                                                                                                            65
          Mechanism of Action                                                                                                            65
          R&D Progress                                                                                                                   65
     Program For Neurological Disorders - Drug Profile                                                                                   66
          Product Description                                                                                                            66
          Mechanism of Action                                                                                                            66
          R&D Progress                                                                                                                   66
     Human Cord Blood Mononuclear Cells + Human Umbilical Cord Mesenchymal Stem Cells - Drug Profile                                     67
          Product Description                                                                                                            67
          Mechanism of Action                                                                                                            67
          R&D Progress                                                                                                                   67
     Memantine - Drug Profile                                                                                                            68
          Product Description                                                
								
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