Dyspepsia - Pipeline Review, H2 2011 by GlobalMarketsDirect

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									Dyspepsia – Pipeline Review, H2 2011




                            Dyspepsia - Pipeline Review, H2 2011
                                                                                          Reference Code: GMDHC1276IDB

                                                                                          Publication Date: August 2011




Dyspepsia – Pipeline Review, H2 2011                                                                              GMDHC1276IDB / Pub August 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied
                                                                                                                                         Page(1)
Dyspepsia – Pipeline Review, H2 2011



Ta b le o f Co n te n ts
Table of Contents                                                                                                  2
List of Tables                                                                                                     5
List of Figures                                                                                                    6
Introduction                                                                                                       7
     Global Markets Direct Report Coverage                                                                         7
Dyspepsia Overview                                                                                                 8
Therapeutics Development                                                                                           9
     An Overview of Pipeline Products for Dyspepsia                                                                9
Dyspepsia Therapeutics under Development by Companies                                                             11
Dyspepsia Therapeutics under Investigation by Universities/Institutes                                             13
Late Stage Products                                                                                               14
     Comparative Analysis                                                                                         14
Mid Clinical Stage Products                                                                                       15
     Comparative Analysis                                                                                         15
Early Clinical Stage Products                                                                                     16
     Comparative Analysis                                                                                         16
Discovery and Pre-Clinical Stage Products                                                                         17
     Comparative Analysis                                                                                         17
Dyspepsia Therapeutics - Products under Development by Companies                                                  18
Dyspepsia Therapeutics - Products under Investigation by Universities/Institutes                                  19
Companies Involved in Dyspepsia Therapeutics Development                                                          20
     GlaxoSmithKline plc                                                                                          20
     Daewoong Pharmaceutical Co., Ltd.                                                                            20
     Dong-A Pharmaceutical Co., Ltd.                                                                              21
     Zeria Pharmaceutical Co Ltd                                                                                  21
     ARYx Therapeutics                                                                                            22
     Tranzyme Pharma, Inc.                                                                                        22
     Rottapharm SpA                                                                                               23
     RaQualia Pharma Inc.                                                                                         23
Dyspepsia - Therapeutics Assessment                                                                               24
     Assessment by Monotherapy Products                                                                           24
     Assessment by Combination Products                                                                           25
     Assessment by Route of Administration                                                                        26
     Assessment by Molecule Type                                                                                  28
Drug Profiles                                                                                                     30
     Z-338 - Drug Profile                                                                                         30
          Product Description                                                                                     30
          Mechanism of Action                                                                                     30
          R&D Progress                                                                                            30
     GSK962040 - Drug Profile                                                                                     31
          Product Description                                                                                     31
          Mechanism of Action                                                                                     31
          R&D Progress                                                                                            31
     ATI-7505 - Drug Profile                                                                                      33
          Product Description                                                                                     33
          Mechanism of Action                                                                                     33
          R&D Progress                                                                                            33


Dyspepsia – Pipeline Review, H2 2011                                                      GMDHC1276IDB / Pub August 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                           Page(2)
Dyspepsia – Pipeline Review, H2 2011


     IMD3 - Drug Profile                                                                                          35
          Product Description                                                                                     35
          Mechanism of Action                                                                                     35
          R&D Progress                                                                                            35
     TZP-102 - Drug Profile                                                                                       36
          Product Description                                                                                     36
          Mechanism of Action                                                                                     36
          R&D Progress                                                                                            36
     OPC-12759E - Drug Profile                                                                                    37
          Product Description                                                                                     37
          Mechanism of Action                                                                                     37
          R&D Progress                                                                                            37
     CR 2017 - Drug Profile                                                                                       39
          Product Description                                                                                     39
          Mechanism of Action                                                                                     39
          R&D Progress                                                                                            39
     CR 2945 - Drug Profile                                                                                       40
          Product Description                                                                                     40
          Mechanism of Action                                                                                     40
          R&D Progress                                                                                            40
     DA-6650 - Drug Profile                                                                                       41
          Product Description                                                                                     41
          Mechanism of Action                                                                                     41
          R&D Progress                                                                                            41
     RQ-00201894 - Drug Profile                                                                                   42
          Product Description                                                                                     42
          Mechanism of Action                                                                                     42
          R&D Progress                                                                                            42
     Amoxicillin + Clarythromycin + Omeprazole - Drug Profile                                                     43
          Product Description                                                                                     43
          Mechanism of Action                                                                                     43
          R&D Progress                                                                                            43
     DA-9701 - Drug Profile                                                                                       44
          Product Description                                                                                     44
          Mechanism of Action                                                                                     44
          R&D Progress                                                                                            44
     Amitriptyline - Drug Profile                                                                                 45
          Product Description                                                                                     45
          Mechanism of Action                                                                                     45
          R&D Progress                                                                                            45
     Rabeprazole - Drug Profile                                                                                   46
          Product Description                                                                                     46
          Mechanism of Action                                                                                     46
          R&D Progress                                                                                            46
     Rebamipide - Drug Profile                                                                                    47
          Product Description                                                                                     47
          Mechanism of Action                                                                                     47
          R&D Progress                                                                                            47




Dyspepsia – Pipeline Review, H2 2011                                                      GMDHC1276IDB / Pub August 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                           Page(3)
Dyspepsia – Pipeline Review, H2 2011


     Imipramine - Drug Profile                                                                                               48
          Product Description                                                                                                48
          Mechanism of Action                                                                                                48
          R&D Progress                                                                                                       48
     Nigella Sativa Seeds + Omeprazole - Drug Profile                                                                        49
          Product Description                                                                                                49
          Mechanism of Action                                                                                                49
          R&D Progress                                                                                                       49
     Clarithromycin + Amoxicillin + Omeprazole - Drug Profile                                                                50
          Product Description                                                                                                50
          Mechanism of Action                                                                                                50
          R&D Progress                                                                                                       50
Dyspepsia Therapeutics – Drug Profile Updates                                                                                52
Dyspepsia Therapeutics - Discontinued Products                                                                               55
     Dyspepsia - Featured News                                                                                               56
          Sep 29, 2010: Zeria And Astellas Pharma Submit NDA Of Z-338 /YM443 For Functional Dyspepsia In Japan               56
          Jun 28, 2010: Zeria Announces Positive Phase III Trial Results Of Z-338 In Dyspepsia                               56
Appendix                                                                                                                     58
     Methodology                                                                                                             58
          Coverage                                                                                                           58
          Secondary Research                                                                                                 58
          Primary Research                                                                                                   58
          Expert Panel Validation                                                                                            59
     Contact Us                                                                                                              59
     Disclaimer                                                                                                              59




Dyspepsia – Pipeline Review, H2 2011                                                                 GMDHC1276IDB / Pub August 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                                      Page(4)
Dyspepsia – Pipeline Review, H2 2011




Lis t o f Ta b le s
Number of Products Under Development for Dyspepsia, H2 2011                                                        9

Products under Development for Dyspepsia – Comparative Analysis, H2 2011                                          10

Number of Products under Developme
								
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