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Poisoning - Pipeline Review, Q3 2011

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Poisoning - Pipeline Review, Q3 2011
Poisoning – Pipeline Review, Q3 2011









Poisoning - Pipeline Review, Q3 2011

Reference Code: GMDHC1188IDB



Publication Date: July 2011









Poisoning – Pipeline Review, Q3 2011 GMDHC1188IDB / Pub July 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied

Page(1)

Poisoning – Pipeline Review, Q3 2011







Ta b le o f Co n te n ts

Table of Contents 2

List of Tables 4

List of Figures 5

Introduction 6

Global Markets Direct Report Coverage 6

Poisoning Overview 7

Therapeutics Development 8

An Overview of Pipeline Products for Poisoning 8

Poisoning Therapeutics under Development by Companies 10

Poisoning Therapeutics under Investigation by Universities/Institutes 11

Late Stage Products 12

Comparative Analysis 12

Mid Clinical Stage Products 13

Comparative Analysis 13

Early Clinical Stage Products 14

Comparative Analysis 14

Pre-Clinical Stage Products 15

Comparative Analysis 15

Poisoning Therapeutics - Products under Development by Companies 16

Poisoning Therapeutics - Products under Investigation by Universities/Institutes 17

Companies Involved in Poisoning Therapeutics Development 18

Cangene Corporation 18

PharmAthene, Inc. 18

Mondobiotech Holding AG 19

Aton Pharma, Inc. 19

MicroDose Therapeutx, Inc. 20

Poisoning - Therapeutics Assessment 21

Assessment by Monotherapy Products 21

Assessment by Combination Products 22

Assessment by Route of Administration 23

Assessment by Molecule Type 25

Drug Profiles 27

Protexia - Drug Profile 27

Product Description 27

Mechanism of Action 27

R&D Progress 27

Atropine - Drug Profile 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

Atropine Sulfate - Drug Profile 29

Product Description 29

Mechanism of Action 29

R&D Progress 29

Ricin Immune Globulin - Drug Profile 30

Product Description 30

Mechanism of Action 30





Poisoning – Pipeline Review, Q3 2011 GMDHC1188IDB / Pub July 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied Page(2)

Poisoning – Pipeline Review, Q3 2011





R&D Progress 30

Diazepam - Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

Clonidine - Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

Fructose-1,6-Diphosphate - Drug Profile 33

Product Description 33

Mechanism of Action 33

R&D Progress 33

Carboplatin + Sodium Thiosulfate - Drug Profile 34

Product Description 34

Mechanism of Action 34

R&D Progress 34

Buprenorphine + Naloxone - Drug Profile 35

Product Description 35

Mechanism of Action 35

R&D Progress 35

ATON 004 - Drug Profile 36

Product Description 36

Mechanism of Action 36

R&D Progress 36

ATON 009 - Drug Profile 37

Product Description 37

Mechanism of Action 37

R&D Progress 37

Penicillamine - Drug Profile 38

Product Description 38

Mechanism of Action 38

R&D Progress 38

DasKloster 0210-01 - Drug Profile 39

Product Description 39

Mechanism of Action 39

R&D Progress 39

VINS Polyvalent Antivenom - Drug Profile 40

Product Description 40

Mechanism of Action 40

R&D Progress 40

Poisoning Therapeutics – Drug Profile Updates 41

Poisoning - Featured News 42

Jun 07, 2011: MicroDose Therapeutx Announces Successful Completion Of Phase I Pilot Study Of Inhaled Atropine As Antidote To

Combat Effects Of Nerve Agent Poisoning 42

Jan 04, 2011: Protalix To Present PRX-105 Data At BARDA Industry Day 43

Nov 22, 2010: Soligenix Receives US Patent For RiVax Vaccine Against Ricin Toxin 43

Nov 02, 2010: Soligenix Completes Enrollment And Preliminary Safety Results Of Phase IB Clinical Trial For RiVax 44









Poisoning – Pipeline Review, Q3 2011 GMDHC1188IDB / Pub July 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied Page(3)

Poisoning – Pipeline Review, Q3 2011





Sep 14, 2010: United States FDA grants mondoBIOTECH’s Medicinal Product Candidate DasKloster0210 the Orphan Drug Designation

For The Treatment Of Chron

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