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Liver Failure - Pipeline Review, Q3 2011


Liver Failure - Pipeline Review, Q3 2011 Summary Global Markets Direct’s, 'Liver Failure - Pipeline Review, Q3 2011', provides an overview of the Liver Failure therapeutic pipeline. This report provides information on the therapeutic development for Liver Failure, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Liver Failure. 'Liver Failure - Pipeline Review, Q3 2011' is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - A snapshot of the global therapeutic scenario for Liver Failure. - A review of the Liver Failure products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Liver Failure pipeline on the basis of therapeutic class, route of administration and molecule type. - Profiles of late-stage pipeline products featuring sections on product description, mechanism of action and research & development progress. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Reasons to buy - Identify and understand important and diverse types of therapeutics under development for Liver Failure. - Identify emerging players with potentially strong product portfolio and design effective counter-strategies

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									Liver Failure – Pipeline Review, Q3 2011

                         Liver Failure - Pipeline Review, Q3 2011
                                                                                          Reference Code: GMDHC1161IDB

                                                                                          Publication Date: July 2011

Liver Failure – Pipeline Review, Q3 2011                                                                                GMDHC1161IDB / Pub July 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied
Liver Failure – Pipeline Review, Q3 2011

Ta b le o f Co n te n ts
Table of Contents                                                                                                                           2
List of Tables                                                                                                                              3
List of Figures                                                                                                                             3
Introduction                                                                                                                                4
     Global Markets Direct Report Coverage                                                                                                  4
Liver Failure Overview                                                                                                                      5
Therapeutics Development                                                                                                                    6
     An Overview of Pipeline Products for Liver Failure                                                                                     6
Liver Failure Therapeutics under Development by Companies                                                                                   8
Liver Failure Therapeutics under Investigation by Universities/Institutes                                                                   9
Late Stage Products                                                                                                                        10
     Comparative Analysis                                                                                                                  10
Mid Clinical Stage Products                                                                                                                11
     Comparative Analysis                                                                                                                  11
Pre-Clinical Stage Products                                                                                                                12
     Comparative Analysis                                                                                                                  12
Liver Failure Therapeutics - Products under Development by Companies                                                                       13
Liver Failure Therapeutics - Products under Investigation by Universities/Institutes                                                       14
Companies Involved in Liver Failure Therapeutics Development                                                                               15
     Angion Biomedica Corp.                                                                                                                15
Liver Failure - Therapeutics Assessment                                                                                                    16
     Assessment by Monotherapy Products                                                                                                    16
     Assessment by Route of Administration                                                                                                 17
     Assessment by Molecule Type                                                                                                           19
Drug Profiles                                                                                                                              21
     N-Acetylcysteine - Drug Profile                                                                                                       21
          Product Description                                                                                                              21
          Mechanism of Action                                                                                                              21
          R&D Progress                                                                                                                     21
     Allogenic Bone Marrow Stem Cells Transplant - Drug Profile                                                                            22
          Product Description                                                                                                              22
          Mechanism of Action                                                                                                              22
          R&D Progress                                                                                                                     22
     Umbilical Cord Mesenchymal Stem Cells - Drug Profile                                                                                  23
          Product Description                                                                                                              23
          Mechanism of Action                                                                                                              23
          R&D Progress                                                                                                                     23
     ALF-5755 - Drug Profile                                                                                                               24
          Product Description                                                                                                              24
          Mechanism of Action                                                                                                              24
          R&D Progress                                                                                                                     24
     Liver Failure - Featured News                                                                                                         25
          Mar 16, 2011: Digna Biotech And Biotecnol Receive Spanish Approval For Phase I Clinical Studies Of Cardiotrophin I               25
          Mar 10, 2011: Digna Biotech And Biotecnol 
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