Syndax Pharmaceuticals, Inc. – Product Pipeline Review – Q2 2011 by GlobalMarketsDirect

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									         Syndax Pharmaceuticals, Inc. – Product Pipeline
                      Review – Q2 2011
                                                                                          Reference Code: GMDHC1289CDB

                                                                                               Publication Date: JULY 2011




Syndax Pharmaceuticals, Inc. – Product Pipeline Review – Q2 2011                           GMDHC1289CDB / Published JULY 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied                                Page(1)
Syndax Pharmaceuticals, Inc. – Product Pipeline Review




Ta b le o f Co n te n ts
Table of Contents                                                                                                      2
List of Tables                                                                                                         4
List of Figures                                                                                                        4
Syndax Pharmaceuticals, Inc. Snapshot                                                                                  5
    Syndax Pharmaceuticals, Inc. Overview                                                                              5
    Key Information                                                                                                    5
    Key Facts                                                                                                          5
Syndax Pharmaceuticals, Inc. – Research and Development Overview                                                       6
    Key Therapeutic Areas                                                                                              6
Syndax Pharmaceuticals, Inc. – Pipeline Review                                                                         9
    Pipeline Products by Stage of Development                                                                          9
    Pipeline Products – Monotherapy                                                                                   10
    Pipeline Products – Combination Treatment Modalities                                                              11
Syndax Pharmaceuticals, Inc. – Pipeline Products Glance                                                               12
    Syndax Pharmaceuticals, Inc. Clinical Stage Pipeline Products                                                     12
         Phase II Products/Combination Treatment Modalities                                                           12
         Phase I Products/Combination Treatment Modalities                                                            13
Syndax Pharmaceuticals, Inc. – Drug Profiles                                                                          14
    Aldesleukin + Entinostat                                                                                          14
         Product Description                                                                                          14
         Mechanism of Action                                                                                          14
         R&D Progress                                                                                                 14
    Arimidex + Entinostat                                                                                             15
         Product Description                                                                                          15
         Mechanism of Action                                                                                          15
         R&D Progress                                                                                                 15
    Aromasin + Entinostat                                                                                             16
         Product Description                                                                                          16
         Mechanism of Action                                                                                          16
         R&D Progress                                                                                                 16
    Entinostat + Aromasin                                                                                             17
         Product Description                                                                                          17
         Mechanism of Action                                                                                          17
         R&D Progress                                                                                                 17
    Femara + Entinostat                                                                                               19
         Product Description                                                                                          19
         Mechanism of Action                                                                                          19
         R&D Progress                                                                                                 19
    Leukine + Entinostat                                                                                              20
         Product Description                                                                                          20
         Mechanism of Action                                                                                          20
         R&D Progress                                                                                                 20
    NCI-7759                                                                                                          21
         Product Description                                                                                          21
         Mechanism of Action                                                                                          21
         R&D Progress                                                                                                 21




Syndax Pharmaceuticals, Inc. – Product Pipeline Review – Q2 2011                          GMDHC1289CDB / Published JULY 2011

©Global Markets Direct.. This report is a licensed product and is not to be photocopied                              Page(2)
Syndax Pharmaceuticals, Inc. – Product Pipeline Review



    Nexavar + Entinostat                                                                                                  22
         Product Description                                                                                              22
         Mechanism of Action                                                                                              22
         R&D Progress                                                                                                     22
    SNDX 275                                                                                                              23
         Product Description                                                                                              23
         Mechanism of Action                                                                                              23
         R&D Progress                                                                                                     23
    Tarceva + SNDX-275                                                                                                    24
         Product Description                                                                                              24
         Mechanism of Action                                                                                              24
         R&D Progress                                                                                                     24
    Vidaza + Entinostat                                                                                                   26
         Product Description                                                                                              26
         Mechanism of Action                                                                                              26
         R&D Progress                                                                                                     26
    Clolar + Entinostat                                                                                                   27
         Product Description                                                                                              27
         Mechanism of Action                                                                                              27
         R&D Progress                                                                                                     27
    Gleevec + Entinostat                                                                                                  28
         Product Description                                                                                              28
         Mechanism of Action                                                                                              28
         R&D Progress                                                                                                     28
Syndax Pharmaceuticals, Inc. – Pipeline Analysis                                                                          29
    Syndax Pharmaceuticals, Inc. – Pipeline Products by Therapeutic Class                                                 29
    Syndax Pharmaceuticals, Inc. - Pipeline Products By Target                                                            31
    Syndax Pharmaceuticals, Inc. – Pipeline Products by Route of Administration                                           32
    Syndax Pharmaceuticals, Inc. – Pipeline Products by Molecule Type                                                     33
Syndax Pharmaceuticals, Inc. – Recent Pipeline Updates                                                                    34
Syndax Pharmaceuticals, Inc. – Locations And Subsidiaries                                                                 36
    Head Office                                                                                                           36
Financial Deals Landscape                                                                                                 37
    Syndax Pharmaceuticals, Inc., Deals Summary, 2004 to 2011                                                             37
    Syndax Pharmaceuticals, Inc. Detailed Deal Summary                                                                    38
         Venture Financing                                                                                                38
         Syndax Pharmaceuticals Raises $9 Million In Series A Financing                                                   38
         Syndax Pharmaceuticals Secures
								
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