Narcolepsy - Pipeline Review, Q2 2011 by GlobalMarketsDirect

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									Narcolepsy – Pipeline Review, Q2 2011




                           Narcolepsy - Pipeline Review, Q2 2011
                                                                                          Reference Code: GMDHC632IDB

                                                                                          Publication Date: June 2011




Narcolepsy – Pipeline Review, Q2 2011                                                                                   GMDHC632IDB / Pub June 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied
                                                                                                                                            Page(1)
Narcolepsy – Pipeline Review, Q2 2011



Ta b le o f Co n te n ts
Table of Contents                                                                                               2
List of Tables                                                                                                  3
List of Figures                                                                                                 4
Introduction                                                                                                    5
     Global Markets Direct Report Coverage                                                                      5
Narcolepsy Overview                                                                                             6
Therapeutics Development                                                                                        7
     An Overview of Pipeline Products for Narcolepsy                                                            7
Narcolepsy Therapeutics under Development by Companies                                                          9
Narcolepsy Therapeutics under Investigation by Universities/Institutes                                         10
Late Stage Products                                                                                            11
     Comparative Analysis                                                                                      11
Mid Clinical Stage Products                                                                                    12
     Comparative Analysis                                                                                      12
Early Clinical Stage Products                                                                                  13
     Comparative Analysis                                                                                      13
Pre-Clinical Stage Products                                                                                    14
     Comparative Analysis                                                                                      14
Narcolepsy Therapeutics - Products under Development by Companies                                              15
Narcolepsy Therapeutics - Products under Investigation by Universities/Institutes                              16
Companies Involved in Narcolepsy Therapeutics Development                                                      17
     Johnson & Johnson                                                                                         17
     Evotec Aktiengesellschaft                                                                                 17
     Arena Pharmaceuticals, Inc.                                                                               18
     BIOPROJET SCR                                                                                             18
Narcolepsy - Therapeutics Assessment                                                                           19
     Assessment by Monotherapy Products                                                                        19
     Assessment by Combination Products                                                                        20
     Assessment by Route of Administration                                                                     21
     Assessment by Molecule Type                                                                               23
Drug Profiles                                                                                                  25
     APD916 - Drug Profile                                                                                     25
          Product Description                                                                                  25
          Mechanism of Action                                                                                  25
          R&D Progress                                                                                         25
     BF2.649 - Drug Profile                                                                                    26
          Product Description                                                                                  26
          Mechanism of Action                                                                                  26
          R&D Progress                                                                                         26
     Biaxin - Drug Profile                                                                                     28
          Product Description                                                                                  28
          Mechanism of Action                                                                                  28
          R&D Progress                                                                                         28
     JNJ-17216498 - Drug Profile                                                                               30
          Product Description                                                                                  30
          Mechanism of Action                                                                                  30
          R&D Progress                                                                                         30


Narcolepsy – Pipeline Review, Q2 2011                                                     GMDHC632IDB / Pub June 2011
© Global Markets Direct. This report is a licensed product and is not to be photocopied                        Page(2)
Narcolepsy – Pipeline Review, Q2 2011


     EVT501 - Drug Profile                                                                                                   31
          Product Description                                                                                                31
          Mechanism of Action                                                                                                31
          R&D Progress                                                                                                       31
     BF2.649 + Modafinil - Drug Profile                                                                                      32
          Product Description                                                                                                32
          Mechanism of Action                                                                                                32
          R&D Progress                                                                                                       32
Narcolepsy Therapeutics – Drug Profile Updates                                                                               33
Narcolepsy Therapeutics - Discontinued Products                                                                              34
     Narcolepsy - Featured News                                                                                              35
          Oct 20, 2010: Arena Announces Phase I Results For APD916 For Treatment Of Narcolepsy With Cataplexy                35
Appendix                                                                                                                     36
     Methodology                                                                                                             36
          Coverage                                                                                                           36
          Secondary Research                                                                                                 36
          Primary Research                                                                                                   36
          Expert Panel Validation                                                                                            37
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