Narcolepsy - Pipeline Review, Q2 2011

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Narcolepsy - Pipeline Review, Q2 2011
Narcolepsy – Pipeline Review, Q2 2011









Narcolepsy - Pipeline Review, Q2 2011

Reference Code: GMDHC632IDB



Publication Date: June 2011









Narcolepsy – Pipeline Review, Q2 2011 GMDHC632IDB / Pub June 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied

Page(1)

Narcolepsy – Pipeline Review, Q2 2011







Ta b le o f Co n te n ts

Table of Contents 2

List of Tables 3

List of Figures 4

Introduction 5

Global Markets Direct Report Coverage 5

Narcolepsy Overview 6

Therapeutics Development 7

An Overview of Pipeline Products for Narcolepsy 7

Narcolepsy Therapeutics under Development by Companies 9

Narcolepsy Therapeutics under Investigation by Universities/Institutes 10

Late Stage Products 11

Comparative Analysis 11

Mid Clinical Stage Products 12

Comparative Analysis 12

Early Clinical Stage Products 13

Comparative Analysis 13

Pre-Clinical Stage Products 14

Comparative Analysis 14

Narcolepsy Therapeutics - Products under Development by Companies 15

Narcolepsy Therapeutics - Products under Investigation by Universities/Institutes 16

Companies Involved in Narcolepsy Therapeutics Development 17

Johnson & Johnson 17

Evotec Aktiengesellschaft 17

Arena Pharmaceuticals, Inc. 18

BIOPROJET SCR 18

Narcolepsy - Therapeutics Assessment 19

Assessment by Monotherapy Products 19

Assessment by Combination Products 20

Assessment by Route of Administration 21

Assessment by Molecule Type 23

Drug Profiles 25

APD916 - Drug Profile 25

Product Description 25

Mechanism of Action 25

R&D Progress 25

BF2.649 - Drug Profile 26

Product Description 26

Mechanism of Action 26

R&D Progress 26

Biaxin - Drug Profile 28

Product Description 28

Mechanism of Action 28

R&D Progress 28

JNJ-17216498 - Drug Profile 30

Product Description 30

Mechanism of Action 30

R&D Progress 30





Narcolepsy – Pipeline Review, Q2 2011 GMDHC632IDB / Pub June 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied Page(2)

Narcolepsy – Pipeline Review, Q2 2011





EVT501 - Drug Profile 31

Product Description 31

Mechanism of Action 31

R&D Progress 31

BF2.649 + Modafinil - Drug Profile 32

Product Description 32

Mechanism of Action 32

R&D Progress 32

Narcolepsy Therapeutics – Drug Profile Updates 33

Narcolepsy Therapeutics - Discontinued Products 34

Narcolepsy - Featured News 35

Oct 20, 2010: Arena Announces Phase I Results For APD916 For Treatment Of Narcolepsy With Cataplexy 35

Appendix 36

Methodology 36

Coverage 36

Secondary Research 36

Primary Research 36

Expert Panel Validation 37

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