Cushing's Syndrome - Pipeline Review, Q2 2011 by GlobalMarketsDirect

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									Cushing's Syndrome – Pipeline Review, Q2 2011




          Cushing's Syndrome - Pipeline Review, Q2 2011
                                                                                     Reference Code: GMDHC1008IDB

                                                                                     Publication Date: April 2011




Cushing's Syndrome – Pipeline Review, Q2 2011                                                                       GMDHC1008IDB / Pub April 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied                                                   Page(1)
Cushing's Syndrome – Pipeline Review, Q2 2011



Ta b le o f Co n te n ts
Table of Contents                                                                                                  2
List of Tables                                                                                                     4
List of Figures                                                                                                    4
Introduction                                                                                                       5
    Global Markets Direct Report Coverage                                                                          5
Cushing's Syndrome Overview                                                                                        6
Therapeutics Development                                                                                           7
    An Overview of Pipeline Products for Cushing's Syndrome                                                        7
Cushing's Syndrome Therapeutics under Development by Companies                                                     9
Cushing's Syndrome Therapeutics under Investigation by Universities/Institutes                                    10
Late Stage Products                                                                                               12
    Comparative Analysis                                                                                          12
Mid Clinical Stage Products                                                                                       13
    Comparative Analysis                                                                                          13
Early Clinical Stage Products                                                                                     14
    Comparative Analysis                                                                                          14
Pre-Clinical Stage Products                                                                                       15
    Comparative Analysis                                                                                          15
Cushing's Syndrome Therapeutics - Products under Development by Companies                                         16
Cushing's Syndrome Therapeutics - Products under Investigation by Universities/Institutes                         17
Companies Involved in Cushing's Syndrome Therapeutics Development                                                 18
    Ipsen S.A.                                                                                                    18
    Novartis AG                                                                                                   18
    Corcept Therapeutics Incorporated                                                                             19
    Samaritan Pharmaceuticals, Inc.                                                                               19
    HRA Pharma, SA                                                                                                20
Cushing's Syndrome - Therapeutics Assessment                                                                      21
    Assessment by Monotherapy Products                                                                            21
    Assessment by Route of Administration                                                                         22
    Assessment by Molecule Type                                                                                   24
Drug Profiles                                                                                                     26
    Pasireotide - Drug Profile                                                                                    26
         Product Description                                                                                      26
         Mechanism of Action                                                                                      26
         R&D Progress                                                                                             26
    Mifedren - Drug Profile                                                                                       28
         Product Description                                                                                      28
         Mechanism of Action                                                                                      28
         R&D Progress                                                                                             28
    Corlux - Drug Profile                                                                                         29
         Product Description                                                                                      29
         Mechanism of Action                                                                                      29
         R&D Progress                                                                                             29
    SP-6300 - Drug Profile                                                                                        31
         Product Description                                                                                      31
         Mechanism of Action                                                                                      31
         R&D Progress                                                                                             31


Cushing's Syndrome – Pipeline Review, Q2 2011                                               GMDHC1008IDB / Pub April 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied                          Page(2)
Cushing's Syndrome – Pipeline Review, Q2 2011


    Bexarotene for Cushing's Disease - Drug Profile                                                                                    32
         Product Description                                                                                                           32
         Mechanism of Action                                                                                                           32
         R&D Progress                                                                                                                  32
    Mifepristone - Drug Profile                                                                                                        33
         Product Description                                                                                                           33
         Mechanism of Action                                                                                                           33
         R&D Progress                                                                                                                  33
    Cabergoline - Drug Profile                                                                                                         34
         Product Description                                                                                                           34
         Mechanism of Action                                                                                                           34
         R&D Progress                                                                                                                  34
    Rosiglitazone Maleate - Drug Profile                                                                                               35
         Product Description                                                                                                           35
         Mechanism of Action                                                                                                           35
         R&D Progress                                                                                                                  35
    Cabergoline - Drug Profile                                                                                                         36
         Product Description                                                                                                           36
         Mechanism of Action                                                                                                           36
         R&D Progress                                                                                                                  36
    Mifepristone - Drug Profile                                                                                                        37
         Product Description                                                                                                           37
         Mechanism of Action                                                                                                           37
         R&D Progress                                                                                                                  37
    Inhibitors Of ACTH Receptor - Drug Profile                                                                                         38
         Product Description                                                                                                           38
         Mechanism of Action                                                                                                           38
         R&D Progress                                                                                                                  38
Cushing's Syndrome Therapeutics – Drug Profile Updates                                                                                 39
    Cushing's Syndrome - Featured News                                                                                                 40
         Mar 31, 2011: Corcept To Submit NDA For Use Of CORLU
								
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