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Siena Biotech S.p.A. – Product Pipeline Review – Q1 2011 by GlobalMarketsDirect

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Siena Biotech S.p.A. – Product Pipeline Review – Q1 2011 Summary Global Market Direct’s pharmaceuticals report, “Siena Biotech S.p.A. - Product Pipeline Review - Q1 2011” provides data on the company’s research and development focus. The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and dormant projects. This report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company’s corporate website, SEC filings, investor presentations and featured press releases, both from company and industry-specific third party sources, put together by Global Markets Direct’s team. Scope - Siena Biotech S.p.A. - Brief company overview including business description, key information and facts, and its locations and subsidiaries. - Review of current pipeline of Siena Biotech S.p.A. human therapeutic division. - Overview of pipeline therapeutics across various therapy areas. - Coverage of current pipeline molecules in various stages of drug development, including the combination treatment modalities, across the globe. - Product profiles for late stage and clinical stage products of Siena Biotech S.p.A. with complete description of the product’s developmental history, mechanism of action, therapeutic class, target and major milestones. - Recent updates of the Siena Biotech S.p.A.’s pipeline in the last quarter. - Key discontinued and dormant projects. - Latest news and deals relating to the products. Reasons to buy - Evaluate Siena Biotech S.p.A.’s strategic position with total access to detailed information on its product pipeline. - Assess the growth potential of Siena Biotech S.p.A. in its therapy areas of focus. - Identify new drug targets and therapeutic classes in the Siena Biotech S.p.A.’s R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas. - Exploit in-licensing opportunities by identif

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									   Siena Biotech S.p.A. – Product Pipeline Review – Q1
                           2011
                                                                                          Reference Code: GMDHC1109CDB

                                                                                               Publication Date: MAR 2011




Siena Biotech S.p.A. – Product Pipeline Review – Q1 2011                                    GMDHC1109CDB / Published MAR 2011

© Global Markets Direct. This report is a licensed product and is not to be photocopied                               Page(1)
Siena Biotech S.p.A. – Product Pipeline Review




Ta b le o f Co n te n ts
Table of Contents                                                                                                     2
List of Tables                                                                                                        4
List of Figures                                                                                                       4
Siena Biotech S.p.A. Snapshot                                                                                         5
    Siena Biotech S.p.A. Overview                                                                                     5
    Key Information                                                                                                   5
    Key Facts                                                                                                         5
Siena Biotech S.p.A. – Research and Development Overview                                                              6
    Key Therapeutic Areas                                                                                             6
Siena Biotech S.p.A. – Pipeline Review                                                                                8
    Pipeline Products by Stage of Development                                                                         8
    Pipeline Products – Monotherapy                                                                                   9
Siena Biotech S.p.A. – Pipeline Products Glance                                                                      10
    Siena Biotech S.p.A. Clinical Stage Pipeline Products                                                            10
         Phase II Products/Combination Treatment Modalities                                                          10
    Siena Biotech S.p.A.–Early Stage Pipeline Products                                                               11
         Pre-Clinical Products/Combination Treatment Modalities                                                      11
         Discovery Products/Combination Treatment Modalities                                                         12
Siena Biotech S.p.A. – Drug Profiles                                                                                 13
    SEN196                                                                                                           13
         Product Description                                                                                         13
         Mechanism of Action                                                                                         13
         R&D Progress                                                                                                13
    Smoothened Antagonist Program                                                                                    14
         Product Description                                                                                         14
         Mechanism of Action                                                                                         14
         R&D Progress                                                                                                14
    Wnt Signalling Inhibitor                                                                                         15
         Product Description                                                                                         15
         Mechanism of Action                                                                                         15
         R&D Progress                                                                                                15
    GPCR antagonist Program                                                                                          16
         Product Description                                                                                         16
         Mechanism of Action                                                                                         16
         R&D Progress                                                                                                16
    Huntingtin Toxicity Inhibitor                                                                                    17
         Product Description                                                                                         17
         Mechanism of Action                                                                                         17
         R&D Progress                                                                                                17
Siena Biotech S.p.A. – Pipeline Analysis                                                                             18
    Siena Biotech S.p.A. – Pipeline Products by Therapeutic Class                                                    18
    Siena Biotech S.p.A. - Pipeline Products By Target                                                               19
    Siena Biotech S.p.A. – Pipeline Products by Molecule Type                                                        20
Siena Biotech S.p.A. – Locations And Subsidiaries                                                                    21
    Head Office                                                                                                      21
    Other Locations & Subsidiaries                                                                                   21




Siena Biotech S.p.A. – Product Pipeline Review – Q1 2011                                  GMDHC1109CDB / Published MAR 2011

©Global Markets Direct.. This report is a licensed product and is not to be photocopied                             Page(2)
Siena Biotech S.p.A. – Product Pipeline Review



Recent Developments                                                                                                                  22
         Jan 08, 2010: Siena Biotech Announces FDA and EMEA Orphan Drug Designations and Phase I Clinical Study of SEN0014196 for the
         Treatment of Huntington’s Disease.                                                                                           22
Financial Deals Landscape                                                                                                            23
    Siena Biotech S.p.A., Deals Summary, 2004 to 2011                                                                                23
    Siena Biotech S.p.A. Detailed Deal Summary                                                                                       24
         Licensing Agreements                                                                                                        24
         Aureus Pharma Enters Into Licensing Agreement With Siena Biotech                                                            24
Appendix                                                                                                                             25
    Methodology                                                                                                                      25
         Coverage                                                                                                                    25
         Secondary Research                                                                                                          25
         Primary Research                                                                                                            25
         Expert Panel Validation                                                                                                     26
    Contact Us                                                                                                                       26
    Disclaimer                                                                                                                       26




Siena Biotech S.p.A. – Product Pipeline Review – Q1 2011                                          GMDHC1109CDB / Published MAR 2011

©Global Markets Direct.. This report is a licensed product and is not to be photocopied                                             Page(3)
Siena Biotech
								
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