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Supplemental Table S2 - Exon

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NCBI

accession Stop Average

number and Seq size Link to First codon? codon

Seq name Description link (aa) CDS codon (*) volatility

Putative secreted proteins

Proteins with presumed or experimentally validated function

D7 and OBP family

Ctar-34 215259727

long form D7 salivary protein - truncated at 5 prime 284 Ctar-34 T * 0.79340

Ctar-35 long form D7 salivary protein 215259739 313 Ctar-35 M * 0.79354

Ctar-36 215259751

long form D7 salivary protein - truncated at 5 prime 266 Ctar-36 L * 0.79103

Ctar-37 long form D7 salivary protein 215259765 321 Ctar-37 M * 0.79145

Ctar-38 long form D7 salivary protein 215259781 321 Ctar-38 M * 0.79293

Ctar-40 long form D7clu1 salivary protein - fragment 215259803 268 Ctar-40 A 0.79328

Ctar-371 salivary short D7 protein 215259769 158 Ctar-371 M * 0.79209

Ctar-173 long form D7 - truncated at 5 prime 215259515 260 Ctar-173 V * 0.76276

Ctar-195 putative salivary odorant binding protein 215259537 148 Ctar-195 M * 0.78847

Ctar-525 215259893

general odorant-binding protein 99a - truncated at 5 prime 95 Ctar-525 V * 0.79306

30 kDa antigen/Aegyptin family

Ctar-103 215259453

putative 30 kDa allergen-like protein- truncated at 5 prime 215 Ctar-103 T * 0.76276

Ctar-104 putative 30 kDa allergen-like protein 215259455 223 Ctar-104 M * 0.76512

Ctar-105 salivary secreted protein 215259457 223 Ctar-105 M * 0.76771

Ctar-49 salivary secreted protein of the Aegyptin family 215259867 213 Ctar-49 M * 0.75607

Ctar-50 putative 30 kDa allergen-like protein 215259879 213 Ctar-50 M * 0.75364

Ctar-51 putative 30 kDa allergen-like protein 215259885 213 Ctar-51 M * 0.75329

Ctar-55 30 kDa salivary gland allergen/Aegyptin 215259899 246 Ctar-55 M * 0.78627

Ctar-57 30 kDa salivary gland allergen/Aegyptin -2 215259911 240 Ctar-57 M * 0.78923

Mucins

Ctar-246 215259589

putative threonine-rich salivary mucin - truncated at 5 prime 136 Ctar-246 A * 0.72249

Ctar-429 215259827

putative threonine-rich salivary mucin - truncated at 5 prime 142 Ctar-429 G * 0.72839

Ctar-261 putative salivary secreted mucin 3 215259611 264 Ctar-261 M * 0.77020

Ctar-581 salivary mucin - truncated at 5 prime 215259919 123 Ctar-581 N * 0.76457

Enzymes

Maltase/Amylase family

Ctar-25 salivary alpha-glucosidase 215259593 584 Ctar-25 M * 0.77484

Ctar-28 alpha-glucosidase - fragment 215259637 298 Ctar-28 R 0.77319

Ctar-293 alpha-amylase - truncated at 5 prime 215259659 143 Ctar-293 D * 0.76346

Ctar-425 alpha-amylase - fragment 215259821 297 Ctar-425 G 0.76891

Ctar-789 alpha-amylase - fragment 215259989 226 Ctar-789 R 0.75495

Endonuclease

Ctar-473 deoxyribonuclease I - fragment 215259857 234 Ctar-473 Q 0.77867

Phosphatase

Ctar-194 prime

salivary alkaline phosphatase - truncated at 5 215259535 150 Ctar-194 P * 0.74519

Serine protease

Ctar-280 serine protease htra2 - truncated at 5 prime 215259639 127 Ctar-280 R * 0.75139

Ctar-268 215259617 299 Ctar-268

secreted serine protease possibly involved with prophenoloxidase activation - fragment D 0.75991

Ctar-270 215259619

trypsin-like salivary secreted protein - truncated at 5 prime 259 Ctar-270 G * 0.76791

Ctar-363 serine protease - truncated at 5 prime 215259755 107 Ctar-363 V * 0.74960

Ctar-378 proclotting enzyme - truncated at 5 prime 215259777 94 Ctar-378 G * 0.76835

Ctar-556 serine protease - truncated at 5 prime 215259905 105 Ctar-556 S * 0.74741

Immunity-related products

Ctar-370 lysozyme 215259767 148 Ctar-370 M * 0.78303

CT-809 salivary C-type lectin - truncated at 5 prime 215259445 75 CT-809 W * 0.78783

Ctar-239 215259583 295

putative salivary Gram negative bacteria-binding protein - fragment Ctar-239 K 0.76681

Proteins with unknown function

Ubiquitous protein family

Antigen-5 family

Ctar-151 215259503 171

putative salivary antigen 5 family protein 1 - truncated at 5 prime Ctar-151 T * 0.79563

Ctar-438 venom allergen 5 - truncated at 5 prime 215259835 137 Ctar-438 R * 0.77436

Insect specific family

Cys-Rich salivary peptide

Ctar-300 putative salivary cysteine-rich peptide 215259669 113 Ctar-300 M * 0.76342

Ctar-368 putative salivary cysteine-rich peptide 215259761 113 Ctar-368 M * 0.76120

Hematophagous Diptera specific families

41.0 kDa family

Ctar-541 putative 41.9 kDa basic salivary protein 215259897 414 Ctar-541 M * 0.74842

Mosquito specific specific families

23.4 protein family

Ctar-345 putative 23.4 kDa salivary protein 215259733 222 Ctar-345 M * 0.78071

hyp37 family

Ctar-769 conserved hypothetical protein 215259985 233 Ctar-769 M * 0.78020

Culicine specific families

30.5 family

Ctar-129 at 5 prime

putative 30.5 kDa secreted protein - truncated215259483 246 Ctar-129 F * 0.76648

Ctar-43 at 5 prime

30.5 kDa secreted protein 30.5k-1 - truncated 215259829 232 Ctar-43 G * 0.76234

Ctar-44 30.5 kDa secreted protein - truncated at 5 prime 215259837 232 Ctar-44 G * 0.76231

Ctar-45 at 5 prime

30.5 kDa secreted protein 30.5k-1 - truncated 215259845 231 Ctar-45 L * 0.76288

Ctar-46 215259845

30.5 kDa secreted protein 1 - truncated at 5 prime 235 Ctar-46 L * 0.76074

Ctar-47 215259853

30.5 kDa secreted protein 1 - truncated at 5 prime 200 Ctar-47 L * 0.76264

7.8 kDa family

Ctar-761 putative 7.8 kDa secreted peptide 215259983 121 Ctar-761 M * 0.80236

4.2 kDa Culex peptide

Ctar-146 putative salivary basic peptide 4.2K 215259497 61 Ctar-146 M * 0.75449

Ctar-147 putative 4.2 kDa basic salivary peptide 215259499 61 Ctar-147 M * 0.76152

Ctar-208 putative 4.2 kDa basic salivary peptide 215259545 56 Ctar-208 M * 0.78541

Culex specific families

Cysteine and tryptophan rich protein family (CWRP)

Ctar-4 17.2 kDa salivary peptide 215259801 163 Ctar-4 M * 0.79209

Ctar-5 putative 17.2 kDa salivary peptide 215259877 163 Ctar-5 M * 0.79213

Ctar-1 16.7 kDa salivary family member 215259447 114 Ctar-1 M * 0.77761

Ctar-150 putative 13.1 kDa salivary protein 215259501 158 Ctar-150 M * 0.77990

Ctar-790 16 kDa salivary peptide 215259991 167 Ctar-790 M * 0.76021

Ctar-95 15.8 kDa salivary peptide 215260013 157 Ctar-95 M * 0.77759

Ctar-118 16.7 kDa salivary peptide - truncated at 5 prime 215259471 156 Ctar-118 A * 0.77690

Ctar-94 at 5 prime

putative 15.8 kDa salivary peptide - truncated 215260011 102 Ctar-94 A * 0.78690

Ctar-183 at 5 prime

putative 17.5 kDa salivary peptide - truncated 215259521 137 Ctar-183 C * 0.78178

Ctar-11 16.8 kDa salivary peptide - truncated at 5 prime 215259459 134 Ctar-11 G * 0.80351

Ctar-12 16.7 kDa salivary peptide - truncated at 5 prime 215259473 134 Ctar-12 G * 0.79534

Ctar-16 16.7 kDa salivary peptide - truncated at 5 prime 215259509 134 Ctar-16 G * 0.80631

Ctar-10 16.8 kDa salivary peptide - truncated at 5 prime 215259449 134 Ctar-10 G * 0.79269

Ctar-9 16.8 kDa salivary peptide - truncated at 5 prime 215260005 134 Ctar-9 G * 0.79020

Ctar-613 16.8 kDa salivary protein - truncated at 5 prime 215259955 141 Ctar-613 G * 0.78293

Ctar-7 16.8 kDa salivary peptide - truncated at 5 prime 215259971 96 Ctar-7 G * 0.79297

Ctar-18 16.7 kDa salivary peptide - fragment 215259519 115 Ctar-18 I 0.80261

CT-388 at 5 prime

putative 17.5 kDa salivary peptide - truncated 215259443 91 CT-388 N * 0.81408

Ctar-115 at 5 prime

putative 16.3 kDa salivary peptide - truncated 215259465 109 Ctar-115 S * 0.78929

Ctar-17 16.7 kDa salivary peptide - truncated at 5 prime 215259513 131 Ctar-17 T * 0.81127

9.7 kDa Culex peptide

Ctar-520 9.7 kDa salivary peptide - truncated at 5 prime215259891 64 Ctar-520 A * 0.79381

Ctar-29 9.7 kDa salivary peptide - truncated at 5 prime215259651 79 Ctar-29 C * 0.79462

GQP repeat family

Ctar-33 putative GQP-rich salivary protein 215259715 115 Ctar-33 M * 0.74745

Ctar-31 at 5 prime

putative GQP-rich salivary protein - truncated 215259679 91 Ctar-31 N * 0.74941

Ctar-32 at 5 prime

putative GQP-rich salivary protein - truncated 215259695 111 Ctar-32 G * 0.74491

Putative housekeeping proteins

Cytoskeletal

Ctar-139 actin - truncated at 5 prime 215259487 221 Ctar-139 S * 0.75831

Ctar-140 actin 1D - fragment 215259489 302 Ctar-140 G 0.75774

Ctar-217 ribosomal protein L23a - truncated at 5 prime 215259557 208 Ctar-217 K * 0.74037

Ctar-233 troponin I - truncated at 5 prime 215259575 99 Ctar-233 N * 0.82133

Ctar-441 restin - truncated at 5 prime 215259839 245 Ctar-441 S * 0.74278

Ctar-496 215259873

dynein light chain, putative - truncated at 5 prime 105 Ctar-496 E * 0.78309

Extracellular matrix

Ctar-212 aggrecan core protein - fragment 215259549 312 Ctar-212 S 0.70503

Ctar-211 aggrecan core protein - fragment 215259547 260 Ctar-211 E 0.70366

Ctar-256 prime

Chondroitin 6-sulfotransferase - truncated at 5215259603 190 Ctar-256 K * 0.75663

OC-365 vitronectin - truncated at 5 prime 215260021 128 OC-365 A * 0.77941

Ctar-382 fasciclin - truncated at 5 prime 215259785 170 Ctar-382 E * 0.76498

Ctar-383 annexin x - truncated at 5 prime 215259787 133 Ctar-383 G * 0.77401

Immunity

Ctar-348 Sptzle 1B - truncated at 5 prime 215259735 97 Ctar-348 L * 0.76661

Amino acid metabolism

Ctar-145 kynurenine formamidase - truncated at 5 prime 215259495 153 Ctar-145 R * 0.76483

Ctar-357 Puromycin-sensitive aminopeptidase - fragment 215259747 279 Ctar-357 E 0.77688

Ctar-320 DNA-directed RNA polymeraseI 215259697 131 Ctar-320 M * 0.77910

Ctar-369 215259763

conserved hypothetical protein - truncated at 3 prime 157 Ctar-369 M 0.74990

Ctar-480 215259861

conserved hypothetical protein - truncated at 5 prime 106 Ctar-480 A * 0.75309

Ctar-418 glutamate carboxypeptidase - truncated at 5 prime215259817 106 Ctar-418 G * 0.75415

Ctar-501 at 5 prime

threonine dehydratase/deaminase - truncated 215259881 149 Ctar-501 I * 0.75469

Ctar-607 aminomethyltransferase, mitochondrial - fragment 215259949 291 Ctar-607 G 0.74952

Ctar-676 215259963 prime

ezrin-radixin-moesin-binding phosphoprotein 50 - truncated at 5 99 Ctar-676 A * 0.77423

Carbohydrate metabolism

Ctar-274 starch branching enzyme - fragment 215259627 323 Ctar-274 G 0.78132

Ctar-294 hydroxypyruvate isomerase - truncated at 5 prime 215259661 213 Ctar-294 R * 0.77162

Ctar-321 galactokinase - truncated at 5 prime 215259699 232 Ctar-321 I * 0.75328

Ctar-379 6-phosphogluconolactonase - truncated at 5 prime 215259779 185 Ctar-379 C * 0.75119

Ctar-596 prime

UDP-glucuronosyltransferase - truncated at 3 215259939 304 Ctar-596 M 0.76978

Ctar-604 215259945

UDP-glucose pyrophosphorylase - truncated at 5 prime 155 Ctar-604 N * 0.75446

Ctar-646 215259961

Glyceraldehyde 3-phosphate dehydrogenase - truncated at 5 prime 99 Ctar-646 T * 0.77178

Ctar-699 215259969 208 at 5 prime

Nuclear transport receptor LGL2 (importin beta superfamily) - truncated Ctar-699 R * 0.78127

Energy metabolism

Ctar-287 215259645

mitochondrial malate dehydrogenase - truncated at 5 prime 235 Ctar-287 P * 0.74039

Ctar-225 215259563 104 Ctar-225

NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit - truncated at 5 prime R * 0.74569

Ctar-315 215259689

3-hydroxyacyl-coa dehyrogenase - truncated at 5 prime 270 Ctar-315 A * 0.76294

Ctar-326 215259709

ATP synthase beta subunit - truncated at 5 prime 115 Ctar-326 G * 0.76297

Ctar-411 ATP synthase beta subunit - fragment 215259815 306 Ctar-411 R 0.73388

Ctar-364 215259757 279 prime

ubiquinol-cytochrome c reductase complex core protein - truncated at 3 Ctar-364 M 0.73511

Ctar-362 215259753

ATP synthase B chain, mitochondrial - truncated at 5 prime 162 Ctar-362 Q * 0.78391

Ctar-338 malic enzyme - truncated at 5 prime 215259725 87 Ctar-338 E * 0.76795

Ctar-494 malic enzyme - fragment 215259871 306 Ctar-494 G 0.75356

Ctar-291 mitochondrial ATP synthase F chain 215259655 107 Ctar-291 M * 0.78202

Ctar-238 215259581

mitochondrial NADH-ubiquinone oxidoreductase AGGG subunit102 Ctar-238 M * 0.74969

Ctar-470 215259855

ATP synthase B chain, mitochondrial - truncated at 5 prime 139 Ctar-470 V * 0.78472

Ctar-354 conserved hypothetical protein - fragment 215259745 268 Ctar-354 E 0.77351

Ctar-446 215259843

ATP synthase gamma chain, mitochondrial - truncated at 5 prime 218 Ctar-446 A * 0.75667

Ctar-327 215259711

mitochondrial NADH:ubiquinone oxidoreductase B14.7 subunit -148 Ctar-327

truncated at 5 prime F * 0.74865

Ctar-61 40S ribosomal protein S2 - truncated at 5 prime215259953 239 Ctar-61 R * 0.74467

Ctar-255 ribosomal protein S6 - fragment 215259601 230 Ctar-255 K 0.75427

Ctar-571 hexokinase - truncated at 5 prime 215259913 175 Ctar-571 R * 0.76387

Ctar-796 215259997

ubiquinol-cytochrome c reductase complex core protein - fragment187 Ctar-796 C 0.75045

Ctar-290 Citrate synthase - truncated at 5 prime 215259653 146 Ctar-290 E * 0.74716

Ctar-396 ATP-citrate synthase - fragment 215259799 316 Ctar-396 G 0.75137

Ctar-74 NADH dehydrogenase - truncated 215259981 54 Ctar-74 S * 0.75091

Intermediate/oxidant/secondary metabolism

Ctar-692 3-ketoacyl-CoA thiolase - truncated at 5 prime215259967 302 Ctar-692 G * 0.73774

Ctar-435 peroxiredoxin-4 - truncated at 5 prime 215259833 135 Ctar-435 E * 0.76910

Ctar-325 Endoribonuclease XendoU - truncated at 5 prime 215259707 257 Ctar-325 S * 0.76901

Lipid metabolism

Ctar-550 215259901

Acetyl-CoA acetyltransferase - truncated at 5 prime 239 Ctar-550 Q * 0.74663

Ctar-257 215259605

fatty acid synthase S-acetyltransferase - fragment 273 Ctar-257 D 0.75407

Ctar-469 215259851 truncated at 5 prime

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial - 264 Ctar-469 E * 0.78006

Ctar-481 215259863

Long-chain acyl-CoA synthetases - truncated at 5 prime 145 Ctar-481 N * 0.76697

Ctar-515 saposin - truncated at 5 prime 215259887 212 Ctar-515 D * 0.79403

Ctar-619 215259957

glycerol-3-phosphate acyltransferase - truncated at 5 prime 118 Ctar-619 E * 0.74669

Nucleotide metabolism

Ctar-349 at 5 prime

purine biosynthesis protein 6, pur6 - truncated215259737 267 Ctar-349 Q * 0.75719

Ctar-325 Endoribonuclease XendoU - truncated at 5 prime 215259707 257 Ctar-325 S * 0.76901

Ctar-144 kynurenine formamidase - truncated at 5 prime 215259493 128 Ctar-144 T * 0.77386

Nuclear regulation

Ctar-575 Histone H4 - truncated at 5 prime 215259917 97 Ctar-575 G * 0.72556

Ctar-373 215259771

40S ribosomal protein S10 - truncated at 5 prime 124 Ctar-373 H * 0.73923

Ctar-391 anamorsin - truncated at 5 prime 215259793 123 Ctar-391 N * 0.76069

Ctar-566 215259909

Cell cycle-associated protein - truncated at 5 prime 199 Ctar-566 E * 0.77292

Protein export machinery

Ctar-329 clathrin light chain - truncated at 5 prime 215259713 161 Ctar-329 N * 0.78406

Ctar-359 Ras-related GTPase - truncated at 5 prime 215259749 147 Ctar-359 W * 0.77307

Ctar-241 coatomer subunit epsilon - truncated at 3 prime215259585 277 Ctar-241 M 0.77041

Ctar-267 coatomer subunit epsilon - truncated at 3 prime215259615 281 Ctar-267 M 0.77303

Ctar-275 215259629

Clathrin-associated protein medium chain - truncated at 5 prime116 Ctar-275 G * 0.75101

Ctar-475 nuclear RNA export factor 2 - truncated at 5 prime215259859 87 Ctar-475 D * 0.77918

Ctar-485 215259865

glutathione-s-transferase theta, gst - truncated at 5 prime 112 Ctar-485 F * 0.75349

Ctar-589 215259937

translocon-associated protein subunit alpha - truncated at 5 prime 253 Ctar-589 V * 0.74987

Protein modification machinery

Ctar-175 membrane protease 3 - truncated at 5 prime 215259517 267 Ctar-175 P * 0.77093

Ctar-310 heat shock cognate 70 - truncated at 5 prime 215259681 132 Ctar-310 V * 0.78992

Ctar-386 78 kDa glucose-regulated protein - fragment 215259789 300 Ctar-386 K 0.76821

Ctar-228 215259567 162 at 5 prime

Golgi-associated protein/Nedd4 WW domain-binding protein - truncatedCtar-228 P * 0.74559

Ctar-248 215259591

conserved hypothetical protein - truncated at 3 prime 216 Ctar-248 M 0.75959

Ctar-251 215259597

conserved hypothetical protein - truncated at 5 prime 168 Ctar-251 G * 0.77491

Ctar-253 elongation factor 1-beta 215259599 226 Ctar-253 M * 0.77314

Ctar-271 cathepsin l - truncated at 5 prime 215259621 125 Ctar-271 Q * 0.76996

Ctar-276 disulfide-isomerase A6 - truncated at 5 prime 215259631 180 Ctar-276 R * 0.76203

Ctar-277 prefoldin - truncated at 5 prime 215259633 107 Ctar-277 F * 0.79343

Ctar-337 9 - truncated 202

eukaryotic translation initiation factor 3 subunit215259723 at 5 prime Ctar-337 E * 0.77314

Ctar-352 215259743

rhomboid protein 1, mitochondrial - truncated at 5 prime 92 Ctar-352 A * 0.76271

Ctar-400 215259805

peptidyl-prolyl cis-trans isomerase f, ppif - truncated at 5 prime 169 Ctar-400 K * 0.77312

Ctar-426 slender lobes - truncated at 5 prime 215259823 247 Ctar-426 P * 0.73813

Ctar-455 215259847

alpha-1,2-mannosyltransferase alg11 - truncated at 5 prime 184 Ctar-455 P * 0.76503

Ctar-786 215259987

AH receptor-interacting protein - truncated at 5 prime 126 Ctar-786 T * 0.75737

Proteasome machinery

Ctar-313 215259685

26S proteasome regulatory complex ATPase RPT4 - fragment 323 Ctar-313 L 0.74807

Ctar-380 at 3 prime

26S protease regulatory subunit 8 - truncated 215259783 267 Ctar-380 M 0.75814

Ctar-169 ribosomal protein S27a - truncated at 5 prime 215259511 130 Ctar-169 K * 0.77392

Ctar-288 E3 ubiquitin ligase - truncated at 5 prime 215259647 115 Ctar-288 K * 0.75444

Ctar-499 5 prime

proteasome subunit beta type 6 - truncated at 215259875 107 Ctar-499 K * 0.76422

Protein synthesis machinery

Ctar-562 tRNA-binding protein - truncated at 5 prime 215259907 169 Ctar-562 A * 0.75246

Ctar-98 40S ribosomal protein S3 - truncated at 5 prime 215260017 221 Ctar-98 A * 0.74343

Ctar-272 histidyl-tRNA synthetase - fragment 215259623 295 Ctar-272 A 0.75662

Ctar-534 60S ribosomal protein L35a - truncated at 5 prime 215259895 104 Ctar-534 A * 0.75122

Ctar-92 ribosomal protein L7 - truncated at 5 prime 215260009 172 Ctar-92 A * 0.76750

Ctar-230 215259569

transcription elongation factor SPT4 - truncated at 5 prime 91 Ctar-230 D * 0.79363

Ctar-574 215259915

ribosome production factor 1 - truncated at 5 prime 226 Ctar-574 D * 0.76357

Ctar-316 215259691

Mitochondrial ribosomal protein S28 - truncated at 5 prime 169 Ctar-316 F * 0.76484

Ctar-586 60S ribosomal protein L18a - truncated at 5 prime 215259935 145 Ctar-586 F * 0.75818

Ctar-72 ribosomal protein S8 - truncated at 5 prime 215259975 162 Ctar-72 F * 0.75681

Ctar-303 elongation factor 1-gamma - truncated at 5 prime 215259673 156 Ctar-303 F * 0.79917

Ctar-112 40S ribosomal protein S25 - truncated at 5 prime 215259461 97 Ctar-112 G * 0.74515

Ctar-113 ribosomal protein S25 - truncated at 5 prime 215259463 94 Ctar-113 G * 0.74883

Ctar-318 60S ribosomal protein L3 - truncated at 5 prime 215259693 143 Ctar-318 G * 0.76050

Ctar-444 conserved hypothetical protein - fragment 215259841 266 Ctar-444 G 0.76220

Ctar-553 60S ribosomal protein L5 - truncated at 5 prime 215259903 227 Ctar-553 G * 0.75822

Ctar-608 215259951

conserved hypothetical protein - truncated at 5 prime 173 Ctar-608 G * 0.76642

Ctar-641 215259959

mitochondrial ribosomal protein, L46 - truncated at 5 prime 236 Ctar-641 K * 0.76436

Ctar-102 ribosomal protein S4 - truncated at 5 prime 215259451 140 Ctar-102 K * 0.74766

Ctar-227 translation initiation factor if-2 - fragment 215259565 186 Ctar-227 K 0.77567

Ctar-97 40S ribosomal protein S3 - truncated at 5 prime 215260015 165 Ctar-97 L * 0.74410

Ctar-120 60S ribosomal protein L8 - truncated at 5 prime 215259475 202 Ctar-120 L * 0.74781

Ctar-401 elongation factor - fragment 215259807 299 Ctar-401 L 0.76599

Ctar-792 40S ribosomal protein S7 - truncated at 5 prime 215259993 164 Ctar-792 L * 0.75366

Ctar-123 ribosomal protein S19 215259477 156 Ctar-123 M * 0.75035

Ctar-124 40S ribosomal protein S19 215259479 156 Ctar-124 M * 0.75017

Ctar-153 60S ribosomal protein L36 215259505 143 Ctar-153 M * 0.75898

Ctar-154 ribosomal protein L36, putative 215259507 113 Ctar-154 M * 0.75832

Ctar-491 60S ribosomal protein L18a 215259869 177 Ctar-491 M * 0.76259

Ctar-19 60S ribosomal protein L37 215259527 89 Ctar-19 M * 0.74594

Ctar-202 ribosomal protein S27 215259541 84 Ctar-202 M * 0.75533

Ctar-292 vacuolar ATP synthase subunit e 215259657 226 Ctar-292 M * 0.76159

Ctar-394 60S ribosomal protein L10 215259795 218 Ctar-394 M * 0.76608

Ctar-68 60s ribosomal protein L41 215259965 25 Ctar-68 M * 0.79180

Ctar-70 hypothetical protein 215259973 101 Ctar-70 M * 0.76541

Ctar-99 40S ribosomal protein S30 215260019 132 Ctar-99 M * 0.73955

Ctar-232 ribosomal protein S16 - truncated at 5 prime 215259573 103 Ctar-232 P * 0.74147

Ctar-234 215259577

mitochondrial ribosomal protein, S35 - truncated at 5 prime 174 Ctar-234 R * 0.76418

Ctar-73 ribosomal protein S8 - truncated at 5 prime 215259977 195 Ctar-73 R * 0.75581

Ctar-206 ribosomal protein L19 - truncated at 5 prime 215259543 145 Ctar-206 R * 0.77667

Ctar-375 60S ribosomal protein L15 - truncated at 5 prime 215259773 106 Ctar-375 R * 0.76088

Ctar-507 elongation factor Tu - fragment 215259883 310 Ctar-507 R 0.76183

Ctar-193 40S ribosomal protein SA - truncated at 5 prime 215259533 257 Ctar-193 S * 0.75092

Ctar-606 215259947

conserved hypothetical protein - truncated at 5 prime 111 Ctar-606 S * 0.77252

Ctar-797 215259999

hypothetical conserved protein - truncated at 5 prime 231 Ctar-797 S * 0.76076

Ctar-223 60S ribosomal protein L31 - truncated at 5 prime 215259561 106 Ctar-223 T * 0.75023

Ctar-395 5 - truncated 113

eukaryotic translation initiation factor 3 subunit215259797 at 5 prime Ctar-395 T * 0.74562

Ctar-295 60S ribosomal protein L24 - truncated at 5 prime 215259663 90 Ctar-295 V * 0.75790

Ctar-83 40S ribosomal protein S3A - truncated at 5 prime 215260003 154 Ctar-83 V * 0.75844

Ctar-350 amidase - truncated at 5 prime 215259741 109 Ctar-350 Y * 0.73746

Ctar-597 60S ribosomal protein L9 - truncated at 5 prime 215259941 103 Ctar-597 Y * 0.76183

Signal transduction

Ctar-434 215259831 317 fragment

calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type - Ctar-434 E 0.75610

Ctar-141 hypothetical protein - truncated at 5 prime 215259491 220 Ctar-141 Q * 0.74011

Ctar-213 LRR Toll - truncated at 5 prime 215259551 159 Ctar-213 V * 0.77140

Ctar-235 215259579 3 primeCtar-235

guanine nucleotide-binding protein subunit beta 1 - truncated at 209 M 0.74777

Ctar-330 215259717

Predicted G-protein coupled receptor - truncated at 5 prime 212 Ctar-330 N * 0.76532

Ctar-376 215259775 133 Ctar-376

5'-AMP-activated protein kinase catalytic subunit alpha-2 - truncated at 5 prime G * 0.77970

Ctar-389 215259791

recessive suppressor of secretory defect - fragment 302 Ctar-389 T 0.75780

Ctar-420 tyrosine kinase receptor - truncated at 5 prime215259819 269 Ctar-420 T * 0.76807

Transcription machinery

Ctar-250 215259595

conserved hypothetical protein - truncated at 5 prime 196 Ctar-250 A * 0.75602

Ctar-402 truncated 107

transcription initiation factor TFIID subunit 12 -215259809at 5 prime Ctar-402 Q * 0.75609

Ctar-289 conserved hypothetical protein - fragment 215259649 313 Ctar-289 A 0.76472

Ctar-296 nucleolar GTP-binding protein - fragment 215259665 302 Ctar-296 F 0.76876

Transporters and storage

Ctar-323 monocarboxylate transporter - truncated at 5 prime215259703 198 Ctar-323 A * 0.74590

Ctar-333 215259721

Phosphatidylethanolamine binding protein - truncated at 5 prime91 Ctar-333 D * 0.75033

Ctar-245 215259587

Mitochondrial phosphate carrier protein - truncated at 5 prime 208 Ctar-245 E * 0.75699

Ctar-283 215259643

vacuolar ATP synthase 21 kDa proteolipid subunit - truncated at155 5 primeCtar-283 F * 0.74091

Ctar-222 215259559

ATP-binding cassette transporter - truncated at 5 prime 123 Ctar-222 G * 0.77138

Ctar-403 vitellogenin C1 - truncated at 5 prime 215259811 116 Ctar-403 K * 0.79404

Ctar-301 215259671 102 prime

sodium/chloride dependent neurotransmitter transporter - truncated at 5Ctar-301 L * 0.77159

Ctar-125 ferritin light chain-like 215259481 224 Ctar-125 M * 0.76012

Ctar-304 215259675

na+/k+ atpase alpha subunit - truncated at 5 prime 301 Ctar-304 P * 0.76100

Ctar-312 apolipophorin fragment 215259683 298 Ctar-312 T 0.75990

Ctar-459 215259849

polymerase delta-interacting protein - truncated at 5 prime 244 Ctar-459 T * 0.75832

Ctar-405 vitellogenin - truncated at 5 prime 215259813 300 Ctar-405 Y * 0.77327

Unknown conserved

Ctar-258 215259607

conserved hypothetical protein - truncated at 5 prime 234 Ctar-258 G * 0.75977

Ctar-260 215259609

conserved hypothetical protein - truncated at 5 prime 234 Ctar-260 G * 0.75989

Ctar-324 215259705

conserved hypothetical protein - truncated at 5 prime 148 Ctar-324 A * 0.76754

Ctar-367 215259759

conserved hypothetical protein - truncated at 5 prime 193 Ctar-367 A * 0.75942

Ctar-343 215259731

conserved hypothetical protein - truncated at 5 prime 115 Ctar-343 D * 0.75709

Ctar-214 215259553

conserved hypothetical protein - truncated at 5 prime 252 Ctar-214 E * 0.78559

Ctar-190 215259529

conserved hypothetical protein - truncated at 5 prime 131 Ctar-190 E * 0.75630

Ctar-314 215259687

conserved hypothetical protein - truncated at 5 prime 106 Ctar-314 E * 0.77535

Ctar-116 215259467

conserved hypothetical protein - truncated at 5 prime 136 Ctar-116 G * 0.74967

Ctar-117 215259469

conserved hypothetical protein - truncated at 5 prime 232 Ctar-117 G * 0.75419

Ctar-795 215259995

hypothetical conserved protein - truncated at 5 prime 170 Ctar-795 G * 0.75979

Ctar-599 215259943

Predicted membrane protein - truncated at 5 prime 109 Ctar-599 G * 0.74472

Ctar-197 215259539

conserved hypothetical protein - truncated at 5 prime 93 Ctar-197 H * 0.78085

Ctar-184 215259523

conserved hypothetical protein - truncated at 5 prime 101 Ctar-184 I * 0.75720

Ctar-279 mitochondrial 162 at 5 prime

isochorismatase domain-containing protein 2, 215259635 - truncated Ctar-279 K * 0.75867

Ctar-322 215259701

Predicted membrane protein - truncated at 5 prime 145 Ctar-322 L * 0.75479

Ctar-192 putative salivary peptide 215259531 82 Ctar-192 M * 0.77920

Ctar-132 hypothetical conserved secreted protein 215259485 76 Ctar-132 M * 0.76576

Ctar-215 conserved insect protein 215259555 154 Ctar-215 M * 0.74133

Ctar-299 hypothetical protein 215259667 78 Ctar-299 M * 0.75014

Ctar-309 conserved hypothetical protein 215259677 102 Ctar-309 M * 0.76414

Ctar-427 215259825

conserved hypothetical protein - truncated at 3 prime 126 Ctar-427 M 0.77770

Ctar-91 hypothetical conserved secreted protein 215260007 138 Ctar-91 M * 0.73643

Ctar-185 215259525

conserved hypothetical protein - truncated at 5 prime 143 Ctar-185 P * 0.75806

Ctar-805 215260001

conserved hypothetical protein - truncated at 5 prime 65 Ctar-805 P * 0.76695

Ctar-273 215259625

conserved hypothetical protein - truncated at 5 prime 120 Ctar-273 R * 0.73343

Ctar-331 215259719

coiled-coil domain-containing protein 124 - truncated at 5 prime 193 Ctar-331 R * 0.77334

Ctar-340 215259729

conserved hypothetical protein - truncated at 5 prime 122 Ctar-340 R * 0.76830

Ctar-281 215259641

conserved hypothetical protein - truncated at 5 prime 265 Ctar-281 S * 0.78453

Ctar-517 215259889

conserved hypothetical protein - truncated at 5 prime 177 Ctar-517 S * 0.78292

Ctar-737 215259979

conserved hypothetical protein - truncated at 5 prime 82 Ctar-737 S * 0.76920

Ctar-264 conserved hypothetical protein - fragment 215259613 291 Ctar-264 T 0.76826

Ctar-231 215259571

conserved hypothetical protein - truncated at 5 prime 143 Ctar-231 Y * 0.75265

No.

Increased potent

AA (Fold ial

Sum of above Cys SigP Cleavage Mature glyc Percent Percent

residues average) number Result Position MW pI MW pI sites Ser+Thr Gly









0.31 10 33.214 6.04 0 10.4 4.2

0.28 10 SIG 20-21 36.402 5.68 34.341 5.68 0 11 4.1

0.28 9 30.955 7.08 0 11.1 4.1

0.23 10 SIG 16-17 36.396 7.47 34.802 7.07 0 7.7 6.4

0.22 10 SIG 16-17 36.478 7.91 34.899 7.6 0 7.4 6.4

0.26 9 30.569 8.56 0 7.7 6.6

0.30 6 SIG 18-19 18.546 6.95 16.556 6.23 0 9.9 4.3

0.29 8 29.876 5.36 0 12.1 6.4

0.30 7 SIG 20-21 16.696 4.96 14.748 4.96 1 9.3 6

0.44 5 11.087 5.62 0 7.2 3.1



0.40 5 16-17 23.088 4.55 26 21.9 5.5

0.37 5 SIG 23-24 23.835 4.55 21.353 4.48 27 21.6 6.2

0.38 5 SIG 23-24 24.145 4.46 21.533 4.42 25 20.7 5.7

0.26 4 SIG 22-23 23.635 8.76 21.393 8.92 1 13.4 6.9

0.25 4 SIG 22-23 23.699 9.03 21.457 9.15 1 13.8 6.9

0.25 4 SIG 22-23 23.628 9.25 21.444 9.26 1 13.4 7.4

0.44 5 SIG 19-20 26.902 4.67 24.976 4.6 6 8 9.6

0.42 5 SIG 19-20 26.684 4.65 24.732 4.64 8 8.6 8.2



0.95 T(5.78) 0 13.72 4.27 62 47.1 0.7

0.87 T(5.53) 0 14.449 4.29 61 44.8 1.4

0.43 1 SIG 20-21 28.767 4.18 26.752 4.15 13 19 7.8

0.32 0 13.86 5.68 1 16.8 6.4





0.17 1 SIG 19-20 66.831 5.48 64.931 5.41 0 10.6 5.9

0.23 0 34.277 8.51 0 11.6 5

0.35 6 15.527 9.04 0 11.6 11.6

0.18 7 32.958 5.13 1 11.3 7.3

0.32 5 24.946 5.99 0 8.7 10.9



0.34 3 26.714 6.13 0 9.2 8



0.31 2 16.254 8.74 1 11.8 12.4



0.28 0 14.309 9.84 0 13.2 7.8

0.20 13 32.663 5.58 4 9.9 9.9

0.22 4 29.196 7.29 0 9.5 7.6

0.32 4 11.919 9.18 4 12.8 8.3

0.43 4 10.054 6.31 0 13.5 12.5

0.35 6 11.702 9.38 0 10.3 11.2



0.35 W(3.06) 8 SIG 23-24 16.688 8.92 14.239 8.92 0 14.6 5.3

0.56 C(3.48)W(4.02) 5 8.517 4.87 0 11.7 11.7

0.33 W(3.07) 5 33.385 9.55 0 11 11









0.30 8 19.603 5.94 1 12.1 5.2

0.36 6 15.284 8.92 2 15.1 7.2





0.45 C(5.55) 12 SIG 20-21 11.818 8.74 9.775 8.76 0 16.5 8.7

0.47 C(5.55) 12 SIG 20-21 11.74 8.86 9.703 8.87 0 16.5 9.6





0.26 6 SIG 19-20 45.063 9.16 42.987 9.18 5 16.4 7.1





0.33 10 SIG 19-20 25.613 8.87 23.544 8.92 0 14.6 5.8



0.33 2 SIG 22-23 26.359 4.78 23.925 4.72 2 11.8 4.2





0.41 5 26.764 5.85 0 13.6 6

0.40 6 24.946 8.23 0 13.6 4.7

0.41 6 25.013 8.75 0 13.1 5.1

0.42 6 24.88 8.52 0 13.2 5.1

0.40 7 25.32 8.68 0 12.6 5.4

0.32 6 21.596 8.56 2 13.3 5.9



0.50 C(3.45) 8 SIG 18-19 13.807 8.76 11.728 8.77 0 4.1 10.6



0.51 1 SIG 22-23 6.743 10.37 4.337 11.38 0 12.9 6.5

0.47 1 SIG 22-23 6.816 10.37 4.347 11.38 0 11.3 6.5

0.43 2 SIG 22-23 6.393 9.18 3.962 9.4 0 12.3 3.5





0.33 W(4.16) 4 SIG 19-20 18.758 8.62 16.911 8.64 0 9.6 8.4

0.32 W(4.16) 4 SIG 19-20 18.807 8.62 16.912 7.86 0 9.6 8.4

0.25 4 SIG 19-20 13.103 7.68 11.087 7.02 0 13.8 5.2

0.28 W(3.34) 4 SIG 19-20 18.035 8.6 16.071 8.32 0 10.6 7.5

0.33 2 SIG 25-26 19.239 7.86 16.579 7.22 0 11.8 6.5

0.27 W(3.36) 5 SIG 16-17 17.93 8.94 16.233 8.86 3 13.8 8.1

0.29 W(3.38) 4 16-17 18.145 9.51 16.466 9.51 0 11.9 6.9

0.22 3 11.481 6.12 2 13.5 7.7

0.33 W(3.3) 4 15.798 7.16 0 10.8 8.6

0.42 W(3.94) 4 16.067 6.4 0 11 6.6

0.38 W(3.94) 4 15.983 7.17 0 13.2 6.6

0.42 W(3.94) 4 16.096 6.4 0 10.3 6.6

0.40 W(3.37) 4 15.699 6.77 0 16.2 6.6

0.40 W(3.37) 4 15.86 8.7 0 15.4 6.6

0.29 3 16.459 5.82 0 16.7 6.3

0.45 H(4.)W(3.14) 1 11.527 6.46 0 18.4 5.1

0.37 W(3.93) 2 13.806 7.22 0 13.7 6.8

0.43 W(3.31) 3 10.894 5.72 0 10.8 6.5

0.45 W(3.46) 3 12.506 9.1 0 11.7 11.7

0.39 W(4.03) 3 15.786 6.62 0 12.8 6



0.60 C(4.9) 6 7.196 6.75 0 6.2 10.8

0.53 C(5.29) 8 9.281 9.35 1 11.1 6.2



0.99 G(3.41)Q(6.77) 0 SIG 18-19 11.865 6.48 10.016 6.12 1 6.8 23.9

1.33 G(4.31)Q(9.07) 0 9.126 4.68 0 5.4 30.1

1.34 0

G(4.42)P(3.)Q(8.93) 11.139 6.24 1 5.3 31





0.23 5 24.695 5.31 0 15.1 6.7

0.24 4 33.917 5.17 1 14.3 6.2

0.58 0 22.547 11.24 1 9 5.7

1.19 0

E(3.07)N(3.13)R(4.56) 12.781 10.93 0 12.9 1

0.27 4 26.918 9.72 11 18.1 7.6

0.41 5 11.796 6.32 0 16.8 6.5



0.92 S(3.92)T(3.42) 0 29.888 4.42 133 42.9 11

0.97 S(3.63) 0 24.582 4.16 101 38.3 14.8

0.41 2 22.452 6.17 0 6.7 3.1

0.34 1 14.554 4.86 0 7.7 9.2

0.28 3 19.106 5.43 2 12.1 8.1

0.30 3 14.847 4.74 0 9.6 6.7



0.37 5 11.156 8.65 0 12.1 6.1



0.34 H(3.14) 0 17.023 5.9 0 10.3 5.8

0.30 3 32.57 5.78 2 10.2 3.9

0.45 1 CYT 14.878 4.13 0 6.8 7.5

0.33 4 CYT 17.457 7.64 3 15 5

0.43 3 11.968 9.47 0 12 10.2

0.28 0 11.641 6.45 0 12 9.3

0.35 5 16.475 6.1 0 7.2 9.2

0.18 8 31.197 5.39 0 12.5 9.5

0.46 1 10.577 9.64 0 8.9 6.9



0.33 5 37.479 5.14 0 9.8 7.9

0.30 6 23.679 5.99 0 6.5 9.7

0.25 7 25.6 5.61 0 9.7 6.8

0.23 4 20.236 6.92 2 10.6 6.4

0.31 2 SIG 19-20 35.368 5.52 33.217 5.4 0 12.3 3.9

0.34 1 16.971 9.41 0 12 9.5

0.30 3 11.041 4.73 1 13.9 5

0.25 5 24.298 9.03 0 8.5 3.8



0.29 4 24.752 9.24 3 10.5 7.9

0.39 0 11.99 10.47 1 7.5 8.5

0.21 2 29.485 8.64 0 11.7 8.4

0.33 0 12.957 5.21 0 6 6.8

0.33 0 32.419 5.07 3 12.2 11.3

0.36 5 28.986 9.11 1 17 8.1

0.40 2 18.849 6.24 0 4.8 4.2

0.46 2 9.914 4.56 0 10.1 2.2

0.21 7 33.213 6.49 3 10.6 9

0.56 0 CYT 12.575 10.09 0 2.8 11

0.42 W(3.69) 0 SIG 18-19 11.597 6.49 9.619 5.6 1 8.7 8.7

0.43 2 16.132 6.81 0 5 3.5

0.42 2 29.944 8.78 1 10.3 8.1

0.18 5 24.093 5.55 0 14 5.4

0.37 0 -1 15.869 9.84 1 9.9 13.2

0.26 4 26.534 9.96 0 11.9 9.1

0.61 K(3.36) 0 25.78 10.73 1 9.4 3.8

0.26 5 19.325 6.58 0 10.7 9

0.42 4 19.402 8.36 0 14.2 11.1

0.30 1 16.325 9.3 1 10.7 8.1

0.24 9 33.631 4.81 0 12.1 10.9

0.45 0 6.305 8.09 0 7.3 7.3



0.28 5 31.581 7.79 0 9.4 11.4

0.25 1 15.282 6.06 0 9.5 8

0.25 2 29.422 8.34 0 12.6 6.9



0.25 4 25.797 7.8 0 9.5 8.6

0.25 8 30.126 8.76 0 12.3 6.1

0.25 2 29.967 6.85 0 9.3 6

0.28 2 16.079 9.06 1 7.4 6.1

0.36 C(3.45) 14 24.218 5.8 0 9.3 4.2

0.34 4 12.951 5.39 0 15 5.8



0.26 5 29.251 5.99 0 12.2 6.3

0.25 2 29.436 8.34 0 12.6 6.9

0.38 0 14.694 5.57 0 10.8 3.8



0.50 0 10.765 11.21 0 8.1 15.2

0.43 0 13.838 10.1 1 7.9 15.9

0.44 7 13.113 4.53 0 9.6 8.8

0.21 5 22.905 6.48 0 10.4 4.5



0.37 1 18.624 5.11 0 10.4 5.5

0.33 4 16.818 4.89 0 9.3 4

0.33 7 CYT 31.853 5.04 0 10 3.2

0.35 7 CYT 32.486 4.99 0 9.1 2.8

0.28 2 12.914 9.91 0 15.3 7.6

0.31 2 10.246 5.12 2 11.2 1.1

0.29 2 12.645 5.87 0 14 6.1

0.29 0 27.798 4.69 10 15.6 8.6



0.30 10 29.516 4.39 1 12.5 10.3

0.47 0 14.986 4.49 0 6 4.5

0.26 0 33.151 4.77 1 9.8 6.9

0.42 3 17.725 6.59 4 13.9 10.3

0.16 4 SIG 17-18 23.96 4.91 22.252 4.91 0 13.2 7.3

0.27 5 19.59 5.1 0 16.4 4.7

0.34 2 CYT 24.654 4.55 0 9.1 6.5

0.41 3 13.824 4.92 0 11 9.4

0.28 4 20.026 4.86 4 10.9 8.2

0.49 1 12.499 4.66 0 5.5 3.7

0.29 1 24.269 8.85 0 9.8 3.9

0.46 W(3.28) 1 10.317 8.87 0 8.5 10.6

0.34 5 18.575 7.81 0 12.8 12.2

0.32 1 26.297 8.34 13 16.3 7.6

0.30 4 21.198 4.95 0 8.6 5.3

0.38 2 14.613 6.77 1 5.5 2.3



0.24 4 36.324 5.97 1 9.1 6.7

0.25 2 CYT 30.116 6.62 1 8.9 7

0.38 4 15.138 9.93 0 8.3 6.8

0.36 4 13.065 7.07 1 12.8 5.1

0.44 2 11.573 8.62 1 10.1 13.8



0.36 4 18.526 6.96 0 7.6 6.4

0.29 5 23.984 9.3 2 10.2 10.2

0.28 5 33.032 5.4 0 6 9

0.43 2 11.882 11.51 0 8.5 10.4

0.38 1 20.198 10.5 0 6.3 5.7

0.45 4 10.643 7.84 1 9.7 7.5

0.33 2 26.856 9.93 0 11.7 5.2

0.27 3 19.385 5.19 1 9.9 4.7

0.39 1 17.5 10.76 0 11.5 3.4

0.36 2 18.563 10.24 0 6.1 6.1

0.38 W(3.38) 3 18.541 5.53 0 12.6 5.7

0.38 1 10.879 10.21 0 9.1 9.1

0.35 1 10.652 10.21 0 9.4 7.3

0.41 2 15.907 10.04 2 12.3 8.2

0.48 Q(3.37) 0 28.551 6.46 3 13 10.7

0.28 4 25.253 9.18 0 8.7 7.8

0.35 1 19.352 4.95 3 18.2 6.3

0.32 2 26.703 7.82 0 10.8 5.4

0.39 0 16.154 10.3 0 5.6 9.2

0.88 E(3.43) 0 20.629 8.43 5 3.7 4.8

0.28 4 17.842 9.32 3 9.5 10.1

0.35 3 22.197 10.65 0 7.3 13.2

0.26 9 33.171 5.6 1 8.6 7.6

0.38 0 19.271 10.17 0 9.6 3.6

0.33 2 CYT 17.264 10.08 0 8.8 7.5

0.31 2 CYT 17.23 10.08 0 9.4 7.5

0.54 0 CYT 16.958 11.66 0 8.2 4.8

0.44 1 CYT 13.267 11.24 0 7.8 7

0.35 1 CYT 21.162 10.67 0 10 3.9

0.62 5 CYT 9.988 10.71 0 14.3 8.8

0.41 C(3.73) 6 CYT 9.506 9.61 0 12.8 5.8

0.32 2 CYT 25.76 6.87 0 8.3 4.3

0.33 9 CYT 25.305 10.12 0 5.4 8.1

1.36 0 CYT

K(3.8)M(5.95)R(7.23)W(3.01) 3.419 12.96 0 3.8 .

0.44 2 CYT 11.551 9.51 0 7.8 1.9

0.32 2 CYT 14.377 10.06 1 9.7 9

0.35 2 11.722 9.96 0 6.7 7.6

0.26 3 19.985 5.87 1 9.6 5.1

0.39 2 22.052 10.49 0 6.6 7.6

0.56 1 17.506 11.34 1 5.4 4.1

0.37 3 12.124 10.15 0 2.8 8.3

0.22 5 34.199 6.2 0 9.2 7.9

0.33 3 28.198 5.02 1 9.2 6.5

0.46 2 12.603 9.43 0 12.4 2.7

0.30 5 25.944 9.93 0 15.7 8.1

0.39 2 12.598 10.14 3 11.1 2.8

0.43 0 12.591 5.58 3 15.7 3.5

0.77 K(3.01) 0 9.975 11.54 0 6.5 3.3

0.25 4 17.089 8.33 1 10.8 7

0.35 2 11.845 5.47 1 6.3 9.9

0.28 1 11.672 8.08 0 12.4 3.8



0.23 6 34.577 4.88 0 12.1 7.8

0.47 8 24.612 10 9 16.5 4.9

0.51 0 18.144 5.26 0 6.8 4.3

0.31 8 CYT 22.803 7.61 1 15.6 7.5

0.40 5 24.536 8.85 0 13 5.6

0.20 1 15.319 9.07 2 8.9 5.9

0.20 5 34.254 8.52 0 11.7 7.2

0.26 6 31.367 5.86 1 11.4 5.1



0.64 P(4.53) 0 22.548 9.2 6 6 3.5

0.38 1 12.608 7.04 2 5.5 1.8

0.24 8 35.782 8.53 1 14.2 4.7

0.36 2 34.828 5.53 1 6.5 3.9



0.37 2 20.976 4.38 8 14.4 6

0.28 0 10.102 8.14 1 10.8 12.9

0.28 4 22.953 9.1 1 10 6.6

0.55 2 15.933 8.66 0 11.4 13.3

0.34 2 14.317 5.08 0 5.6 4.8

0.44 6 13.513 9.37 1 13.6 2.5

0.52 C(3.59) 7 60-61 11.669 5.14 4.881 4.68 1 10.6 7.7

0.25 3 SIG 19-20 25.294 5.34 23.354 5.24 0 10.5 6.1

0.24 4 34.07 6.15 0 10.8 6.2

0.22 9 31.79 5.4 1 13.2 7.9

0.32 3 27.158 5.47 11 14.1 7.7

0.35 11 33.132 6.02 29 17.7 4.6



0.27 5 27.033 9.03 0 10.5 4.6

0.27 5 27.101 8.91 0 10.5 4.6

0.38 1 16.214 4.37 11 15.2 5.3

0.21 3 21.953 9.1 1 9.2 7.1

0.32 1 13.29 6.56 0 9.4 3.4

0.34 7 27.906 8.99 0 11.3 7.4

0.40 5 14.588 9.62 1 12 6.8

0.35 1 11.982 5.41 0 7.4 9.3

0.43 0 14.218 8.93 7 13.8 10.1

0.38 0 24.69 5.24 12 14 10.6

0.45 8 18.296 6.47 19 22.5 7.5

0.38 1 11.716 8.11 0 9.9 11.7

0.41 4 10.533 4.4 0 7.4 6.3

0.68 0 11.457 4.4 10 13.6 3.9

0.25 3 18.049 6.65 0 9.7 6.1

0.49 1 15-16 16.345 9.61 14.666 9.93 0 7.4 11.5

0.68 C(3.82)Y(4.48) 6 CYT 9.81 8.94 0 6 9.5

0.56 4 SIG 20-21 8.536 10.47 6.341 11.01 0 11.5 1.3

0.39 1 CYT 16.851 9.9 1 16.6 4.5

0.51 3 SIG 23-24 8.48 8.96 6.07 8.61 0 11.3 2.5

0.36 2 SIG 20-21 11.388 8.74 8.929 6.8 0 12.5 11.5

0.50 M(3.94) 1 CYT 13.966 5.5 3 14.1 0.8

0.45 2 SIG 24-25 14.905 4.73 12.319 4.7 5 9.3 5

0.56 0 16.153 4.54 7 11 3.4

0.45 2 7.133 8.3 1 13.6 9.1

0.35 1 12.554 9.37 13 16.4 12.3

0.50 0 22.094 9.41 1 6.1 0.5

0.31 2 13.802 8.66 0 15.3 3.2

0.30 4 30.213 4.89 0 11.9 2.6

0.28 2 20.586 4.82 1 10 5

0.55 C(7.65) 12 8.746 8.49 1 11.9 10.7

0.55 H(5.61) 5 32.393 9.61 15 8.1 15.9

0.26 2 16.35 7.14 1 12.3 4.1

Predic

ted %

Percent TMHMM helice membran Best match to SAL-DIP

Pro result Lenght s e % outside % inside Class Salivary motifs database









1.7 284 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/d7l long form D7clu12 salivary protein

Lipid binding mosquito D7 pattern |Lipid binding D7 WC framew

2.5 313 0

ExpAA=0.28 First60=0.28 PredHel=0 Topology=o s/d7l long form D7clu12 salivary protein

D7 Lipid binding motif - less degenerate pattern |Lipid binding m

2.2 266 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/d7l long form D7clu12 salivary protein

3.4 321 0

ExpAA=0.11 First60=0.11 PredHel=0 Topology=o s/d7l long form D7clu1 salivary protein

D7 Lipid binding motif - less degenerate pattern |Lipid binding D

4 321 0

ExpAA=0.11 First60=0.11 PredHel=0 Topology=o s/d7l long form D7clu1 salivary protein

D7 Lipid binding motif - less degenerate pattern |Lipid binding D

2.9 268 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/d7l long form D7clu1 salivary protein

1.9 158 0

ExpAA=0.11 First60=0.11 PredHel=0 Topology=o s/d7s putative salivary short D7 protein 3

1.5 260 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/d7l long form D7Bclu1 salivary protein d7l1

2 148 0

ExpAA=2.05 First60=2.05 PredHel=0 Topology=o s/obp putative salivary odorant binding protein 1

2.1 95 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i s/obp odorant binding protein



5.5 215 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/30 putative mosquito stringent pattern |

Aegyptin mosquito |Aegyptinsalivary protein

4.8 223 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o s/30 putative salivary protein

5.3 223 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o s/30 putative mosquito stringent pattern |

Aegyptin mosquito |Aegyptinsalivary protein

6.9 213 0

ExpAA=0.28 First60=0.28 PredHel=0 Topology=o s/30 salivary protein

Basic tail type 3 |Aegyptin mosquito |Aegyptin mosquito stringe

6.9 213 0

ExpAA=0.28 First60=0.28 PredHel=0 Topology=o s/30 salivary protein

Basic tail type 3 |Aegyptin mosquito |Aegyptin mosquito stringe

6.5 213 0

ExpAA=2.10 First60=2.09 PredHel=0 Topology=o s/30 salivary protein

Basic tail type 3 |Aegyptin mosquito |Aegyptin mosquito stringe

5.2 246 0

ExpAA=0.11 First60=0.11 PredHel=0 Topology=o s/30 30 kDa salivary mosquito stringent pattern

Aegyptin stringent pattern |Aegyptingland allergen 30k-3

4.9 240 0

ExpAA=0.19 First60=0.19 PredHel=0 Topology=o s/30 30 kDa salivary mosquito stringent pattern

Aegyptin stringent pattern |Aegyptingland allergen 30k-3



3.6 136 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/muc putative salivary mucin

4.1 142 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/muc putative salivary mucin

7.5 264 0

ExpAA=4.14 First60=4.14 PredHel=0 Topology=o s/muc putative salivary secreted mucin 3

2.4 123 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o s/muc putative salivary mucin





4.7 584 0

ExpAA=4.18 First60=4.17 PredHel=0 Topology=o s/enz malt Probable maltase precursor

4 298 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/enz maltase probable salivary maltase precursor

4.8 143 0

ExpAA=0.03 First60=0.03 PredHel=0 Topology=o s/enz amylase putative alpha-amylase

6 297 0

ExpAA=0.19 First60=0.00 PredHel=0 Topology=o s/enz amylase Alpha-amylase I precursor (1,4-alpha-D-glu

6.1 226 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o s/enz amylase salivary amylase



3.8 234 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o s/enz dnase 40 kDa salivary protein SP11



6.5 150 Topology=o122-144i

ExpAA=21.69 First60=0.001PredHel=114.7 81.3 4 s/enz phosphatase salivary alkaline phosphatase



3.9 127 0

ExpAA=0.98 First60=0.98 PredHel=0 Topology=o s/enz serine protease syndecan binding protein

7.2 299 0

ExpAA=0.05 First60=0.00 PredHel=0 Topology=o s/enz serine protease secreted serine protease possibly involved w

4.2 259 0

ExpAA=1.09 First60=0.00 PredHel=0 Topology=o s/enz serine protease trypsin-like salivary secreted protein

4.6 107 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/enz serine protease polyserase 2-like protein

2.1 94 0

ExpAA=0.29 First60=0.19 PredHel=0 Topology=o s/enz serine protease serine protease

4.7 105 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/enz serine protease serine protease



2 148 0

ExpAA=11.81 First60=11.81 PredHel=0 Topology=o s/imm amp abundant salivary lysozyme

3.9 75 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/imm pat putative salivary C-type lectin

6 295 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/imm prp putative salivary Gram negative bacteria-bin









2.3 171 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/ag5 putative salivary antigen 5 family protein 1

5.8 137 0

ExpAA=0.62 First60=0.51 PredHel=0 Topology=o s/ag5 putative secreted protein





3.5 113 0

ExpAA=15.18 First60=15.18 PredHel=0 Topology=o s/cysrich putative salivary cysteine-rich peptide

3.5 113 0

ExpAA=15.18 First60=15.18 PredHel=0 Topology=o s/cysrich putative salivary cysteine-rich peptide





5.5 414 0

ExpAA=4.90 First60=4.83 PredHel=0 Topology=o s/41.9 putative 41.9 kDa basic salivary protein





4.9 222 0

ExpAA=1.21 First60=1.21 PredHel=0 Topology=o s/23.4 putative 23.4 kDa salivary protein



3.4 233 0

ExpAA=0.07 First60=0.07 PredHel=0 Topology=o s/hyp37 putative salivary protein





4.4 246 0

ExpAA=0.05 First60=0.04 PredHel=0 Topology=o s/30.5 putative 30.5 kDa secreted protein

3.4 232 0

ExpAA=1.79 First60=0.00 PredHel=0 Topology=o s/30.5 pattern

30.5 kDa family cysputative |30.5 kDa secreted protein second f

3 232 0

ExpAA=2.42 First60=0.00 PredHel=0 Topology=o s/30.5 pattern

30.5 kDa family cysputative |30.5 kDa secreted protein second f

2.6 231 0

ExpAA=0.79 First60=0.02 PredHel=0 Topology=o s/30.5 pattern

30.5 kDa family cysputative |30.5 kDa secreted protein second f

2.9 235 0

ExpAA=0.43 First60=0.01 PredHel=0 Topology=o s/30.5 pattern

30.5 kDa family cysputative |30.5 kDa secreted protein second f

3 200 0

ExpAA=0.53 First60=0.01 PredHel=0 Topology=o s/30.5 putative 30.5 kDa secreted protein second f



2.4 121 0

ExpAA=0.03 First60=0.03 PredHel=0 Topology=o s/7.8 putative 7.8 kDa secreted peptide



1.6 61 1 27.9 8.2

ExpAA=18.10 First60=18.10 PredHel=1 Topology=o5-22i 63.9 s/4.2 putative 4.2 kDa basic salivary peptide

3.2 61 1 27.9 6.6

ExpAA=18.15 First60=18.15 PredHel=1 Topology=o4-21i 65.6 s/4.2 putative 4.2 kDa basic salivary peptide

1.8 56 1 30.4 60.7

ExpAA=17.16 First60=17.16 PredHel=1 Topology=i5-22o 8.9 s/4.2 putative 4.2 kDa basic salivary peptide





3 163

ExpAA=10.20 First60=9.770PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 17.5 kDa salivary peptide family-l

3 163 0

ExpAA=13.49 First60=12.88 PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 17.2 kDa salivary peptide family-l

2.6 114 0

ExpAA=1.07 First60=1.07 PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 16.7 kDa salivary peptide family-l

1.9 158 1 13.9 2.5

ExpAA=15.71 First60=15.71 PredHel=1 Topology=o4-26i 83.5 s/16.7 putative 13.1 kDa salivary protein

3.5 167 0

ExpAA=7.80 First60=7.80 PredHel=0 Topology=o s/16.7 kDa family |Culex salivary

Culex salivary 16.8 16 kDa salivary peptide 16.8 kDa family-l

3.8 157 0

ExpAA=0.06 First60=0.06 PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 15.8 kDa salivary peptide family-l

1.9 156 1 13.5

ExpAA=21.01 First60=20.90 PredHel=1 Topology=o4-25i

2.6 84 s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 16.7 kDa salivary peptide family-l

3.8 102 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 putative 15.8 kDa salivary peptide

1.4 137 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=i s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 17.5 kDa salivary peptide family-l

2.2 134 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=i s/16.7 kDa family |Culex salivary

Culex salivary 16.8 16 kDa salivary peptide 16.8 kDa family-l

2.2 134 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex salivary

Culex salivary 16.8 16 kDa salivary peptide 16.8 kDa family-l

2.9 134 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex salivary

Culex salivary 16.8 16 kDa salivary peptide 16.8 kDa family-l

2.2 134 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 16.7 kDa salivary peptide family-l

1.5 134 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 16.7 kDa salivary peptide family-l

2.8 141 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 16.8 kDa salivary protein family-l

1 96 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 13.1 kDa salivary protein family-l

2.6 115 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex salivary

Culex salivary 16.8 16 kDa salivary peptide 16.8 kDa family-l

1.1 91

ExpAA=10.19 First60=4.350PredHel=0 Topology=i s/16.7 putative 17.5 kDa salivary peptide

1.8 109 0

ExpAA=0.04 First60=0.00 PredHel=0 Topology=i s/16.7 kDa family |Culex 16.8 kDa

Culex salivary 16.8 putative 16.3 kDa salivary peptide family-l

2.3 131 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/16.7 kDa family |Culex salivary

Culex salivary 16.8 16 kDa salivary peptide 16.8 kDa family-l



3.1 64 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/9.7 9.7 kDa salivary peptide

6.2 79 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/9.7 9.7 kDa salivary peptide



9.4 115 0

ExpAA=7.14 First60=7.14 PredHel=0 Topology=o s/GQP

12.9 91 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/GQP

13.3 111 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o s/GQP





4.4 221 0

ExpAA=0.76 First60=0.06 PredHel=0 Topology=o cs actin

4.9 302 0

ExpAA=2.32 First60=0.00 PredHel=0 Topology=o cs actin

4.3 208 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o cs Rab-protein

. 99 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i cs putative RNA-binding protein

3.2 245 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o cs putative salivary protein

0.9 105 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o cs putative salivary antigen 5 family protein 1



8.2 312 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o extmat putative salivary protein

10.6 260 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o extmat secreted mucin

5.7 190 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o extmat phosphoglycerate dehydrogenase

3.8 128 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o extmat truncated matrix metalloproteinase 1 - miss

6.4 170 Topology=i150-169o 88.2 extmat

ExpAA=20.88 First60=1.121PredHel=111.2 0.6 probable membrane protein

0.7 133 0

ExpAA=0.27 First60=0.21 PredHel=0 Topology=o extmat annexin



3 97 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o imm 25 kDA salivary protein SP06



1.9 153 0

ExpAA=0.05 First60=0.05 PredHel=0 Topology=o met aa kynurenine formamidase

1.8 279 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met aa kDa family-less degenerate pattern |

Culex salivary 16.8 eukaryotic translation initiation factor 3 subu

4.5 131 0

ExpAA=0.21 First60=0.00 PredHel=0 Topology=o met aa 43 kDa salivary protein

5.6 157 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o met aa hypothetical protein

3.7 106

ExpAA=14.54 First60=6.150PredHel=0 Topology=o met aa fatty acyl-CoA elongase

6.5 106 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met aa PAN/APPLE-like domain-containing protein

1.3 149 0

ExpAA=0.11 First60=0.10 PredHel=0 Topology=o met aa NICE-3 family member

3.4 291 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met aa putative serpin

4 99 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i met aa histone H1 gamma-like protein



2.4 323 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o met carb thrombostasin precursor

4.6 213 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met carb syndecan binding protein

2.1 232 0

ExpAA=0.03 First60=0.01 PredHel=0 Topology=o met carb peptide methionine sulfoxide reductase

9.6 185 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o met carb RAS small GTPase

6.1 304 1 Topology=i7-29o

ExpAA=21.81 First60=21.56 PredHel=17.2 90.5 2.3 met carb UDP-glucuronosyl transferase

4.4 155 0

ExpAA=0.49 First60=0.37 PredHel=0 Topology=i met carb glyoxylase

3 99 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met carb hydroxymethylbilane

Aegyptin mosquito stringent pattern | synthase-like protein

4.3 208 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o met carb replication factor C



5.9 235 0

ExpAA=0.23 First60=0.01 PredHel=0 Topology=o met en 30 kDa salivary protein SP56

8.5 104 1 21.2 29.8

ExpAA=19.54 First60=19.54 PredHel=1 Topology=o31-53i 49 met en aquaporin 2

4 270 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o met en dynactin

3.4 115 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met en F0F1-type ATP synthase beta subunit

5.1 306 0

ExpAA=0.10 First60=0.00 PredHel=0 Topology=o met en F0F1-type ATP synthase beta subunit

2.8 279 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met en gSG1b protein

1.2 162 0

ExpAA=6.04 First60=6.04 PredHel=0 Topology=o met en long form D7clu2 salivary protein

7.9 87 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met en malic enzyme

4.8 306 0

ExpAA=0.22 First60=0.00 PredHel=0 Topology=o met en malic enzyme

8.3 107 Topology=o74-96i

ExpAA=21.63 First60=0.001PredHel=120.6 69.2 10.3 met en mitochondrial ATP synthase F chain

6.7 102 0

ExpAA=8.98 First60=4.79 PredHel=0 Topology=o met en mitochondrial NADH-ubiquinone oxidoreduc

1.4 139 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met energy multifunctional 14-3-3 family chaperone

3.3 268 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met en nuclear distribution protein NUDC

3.2 218 0

ExpAA=0.09 First60=0.07 PredHel=0 Topology=o met en polyQ domain-containing hypothetical conse

4 148 4 52.7 11.5 35.8 met en

ExpAA=69.44 First60=42.16 PredHel=4 Topology=i5-27o40-62i69-86o90-107i putative mitochondrial NADH-ubiquinone ox

5.3 239 0

ExpAA=0.52 First60=0.01 PredHel=0 Topology=o met en ribosomal protein S2

4.3 230 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met en ribosomal protein S6

1.7 175 0

ExpAA=13.94 First60=13.92 PredHel=0 Topology=o met en ribosomal protein subunit 3

1.1 187 0

ExpAA=0.05 First60=0.04 PredHel=0 Topology=o met en RNA-binding protein musashi/mRNA cleava

6.7 146 0

ExpAA=8.33 First60=0.06 PredHel=0 Topology=o met en SGS1

4.7 316 0

ExpAA=0.11 First60=0.02 PredHel=0 Topology=o met en succinyl-CoA synthetase alpha subunit

5.5 54 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o em putative 6.3 kDa salivary peptide



5.2 302 0

ExpAA=0.16 First60=0.01 PredHel=0 Topology=o met int acetyl-CoA acetyltransferase

5.1 135 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o met ox mitochondrial ribosomal protein L49

3.8 257 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o met secondary protein kinase 1



4.1 239 0

ExpAA=0.69 First60=0.00 PredHel=0 Topology=o met lipid acetyl-CoA acetyltransferase

5.4 273 0

ExpAA=1.40 First60=0.79 PredHel=0 Topology=o met lipid 26S proteasome regulatory complex ATPas

4.5 264 0

ExpAA=0.45 First60=0.41 PredHel=0 Topology=o met lipid 39 kDa salivary protein

6.1 145 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met lipid mitochondrial ribosomal protein L52

3.2 212 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met lipid 40S ribosomal protein S3A

1.7 118 0

ExpAA=11.97 First60=11.96 PredHel=0 Topology=o met lipid unknown salivary protein



4.1 267

ExpAA=14.05 First60=0.000PredHel=0 Topology=o met nuc putative adenosine deaminase

3.8 257 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o met secondary protein kinase 1

2.3 128 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o met/aa kynurenine formamidase



1 97 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o nr glioma tumor suppressor candidate region g

7.1 124 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o nr ribosomal protein S10E

3.2 123 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=i nr serine/threonine specific protein phosphatas

5.4 199 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o nr SGS5



4.9 161 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pe 29 kDa salivary protein

4.7 147 0

ExpAA=0.03 First60=0.03 PredHel=0 Topology=o pe RAB family GTPase

1.8 277 0

ExpAA=0.72 First60=0.00 PredHel=0 Topology=o pe PA26-T3 nuclear protein-like protein

1.7 281 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o pe PA26-T3 nuclear protein-like protein

3.4 116 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pe actin

4.5 87 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pe translation initiation factor 3 subunit h

4.4 112 0

ExpAA=0.42 First60=0.29 PredHel=0 Topology=o pe 37.2 kDa salivary protein

5.4 253 8.7 66

ExpAA=22.24 First60=0.021PredHel=1 Topology=o167-189i 25.3 pe activating transcription factor



4.1 267 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o pm serine protease

3.7 132 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pm heat shock cognate 70

4.9 300 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o pm heat shock cognate 70

5.5 162 Topology=o59-81i88-107o120-137i

ExpAA=61.36 First60=3.473PredHel=335.8 44.4 19.8 pm homolog of an. stephensi hyp37.3 putative s

4.5 216 0

ExpAA=0.09 First60=0.08 PredHel=0 Topology=o pm SGS4

4.7 168 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pm flavin-containing monooxygenase

4.3 226 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pm elongation factor 1 beta

2.4 125 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=i pm cathepsin L

5.5 180 0

ExpAA=0.05 First60=0.00 PredHel=0 Topology=o pm protein disulfide isomerase

1.8 107 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pm putative calreticulin

2.9 202 0

ExpAA=0.05 First60=0.05 PredHel=0 Topology=o pm 42 kDa yellow-related salivary protein SP03

5.3 92 1 23.9 16.3

ExpAA=38.41 First60=30.32 PredHel=1 Topology=o15-37i 59.8 pm putative 13.3 kDa salivary protein

3.5 169 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pm cyclophylin

7.6 247 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o pm unknown salivary protein

1.6 184 0

ExpAA=0.23 First60=0.00 PredHel=0 Topology=o pm prophenoloxidase activator

4.7 126 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o pm FKBP-type peptidyl-prolyl cis-trans isomera



5.2 323 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o prot 26S proteasome regulatory complex ATPas

4.4 267 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o prot 26S proteasome regulatory chain 4

2.3 130 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o prot ribosomal protein S27a

6.8 115 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=i prot putative hyaluronoglucosaminidase

3.7 107 0

ExpAA=3.87 First60=3.86 PredHel=0 Topology=o prot proteasome subunit beta type 6 precursor-li



9.3 169 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps salivary apyrase

5.8 221 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps long form D7clu2 salivary protein

3.3 295 0

ExpAA=0.15 First60=0.00 PredHel=0 Topology=o ps putative prophenoloxidase activating protein

2.8 104 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps ribosomal protein L35

5.1 172 0

ExpAA=0.05 First60=0.02 PredHel=0 Topology=o ps ribosomal protein L7

4.3 91 0

ExpAA=0.04 First60=0.02 PredHel=0 Topology=o ps protein disulfide isomerase

3.9 226 0

ExpAA=0.20 First60=0.00 PredHel=0 Topology=o ps U3 small nucleolar ribonucleoprotein compo

4.1 169 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps 49 kDa salivary protein

2.7 145 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps 60S ribosomal protein L18a

2.4 162 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=i ps ribosomal protein S8

3.8 156 0

ExpAA=0.03 First60=0.01 PredHel=0 Topology=o ps elongation factor 1-gamma

4 97 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps 40S ribosomal protein S25

4.2 94 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i ps 40S ribosomal protein S25

2.1 143 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o ps ribosomal protein L3

7.8 266 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps putative salivary mucin

2.6 227 0

ExpAA=8.98 First60=8.98 PredHel=0 Topology=o ps 60S ribosomal protein L5

2.3 173 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps putative secreted protein

3.8 236 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps ribosomal protein S16

2.1 140 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps ribosomal protein S4

7.9 186 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps

6.5 165 0

ExpAA=0.03 First60=0.02 PredHel=0 Topology=o ps long form D7clu2 salivary protein

5.9 202 0

ExpAA=0.13 First60=0.13 PredHel=0 Topology=o ps 60S ribosomal protein L2/L8

6.6 299 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps mitochondrial ATP synthase alpha subunit

6 164 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps translation initiation factor 2B beta subunit

3.8 156 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o ps ribosomal protein S19

3.8 156 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o ps ribosomal protein S19

1.4 143 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps 60S ribosomal protein L36

2.6 113 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps 60S ribosomal protein L36

4.4 177 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o ps 60S ribosomal protein L18a

. 89 0

ExpAA=1.92 First60=0.00 PredHel=0 Topology=i ps 60S ribosomal protein L37

9.3 84 0

ExpAA=0.17 First60=0.14 PredHel=0 Topology=o ps ribosomal protein S27

1.7 226 0

ExpAA=1.14 First60=0.00 PredHel=0 Topology=o ps vacuolar ATP synthase subunit E

5.4 218 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps ribosomal protein L10

. 25 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i ps

6.8 101 2

ExpAA=43.94 First60=27.27 PredHel=2 Topology=i21-40o55-77i

40.6 14.9 44.6 ps putative salivary mucin

3.7 132 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps anopheles stephensi ubiquitin

4.8 103 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o ps ribosomal protein S16

4 174 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps hypothetical protein

2.5 195 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o ps ribosomal protein S8

0.7 145 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i ps ribosomal protein L19

4.6 106 0

ExpAA=0.05 First60=0.01 PredHel=0 Topology=o ps 60S ribosomal protein L27a

4.1 310 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o ps elongation factor 1 alpha

7.7 257 0

ExpAA=0.40 First60=0.02 PredHel=0 Topology=o ps 40S ribosomal protein SA

3.5 111

ExpAA=13.10 First60=0.000PredHel=0 Topology=o ps salivary purine nucleosidase

4.3 231 0

ExpAA=1.98 First60=0.00 PredHel=0 Topology=o ps putative salivary secreted 30 kDa allergen-l

5.6 106 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i ps 60S ribosomal protein L31

4.3 113 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o ps eukaryotic translation initiation factor 3 subu

3.3 90 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i ps ribosomal protein L24

4.5 154 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ps 40S ribosomal protein S3A

7.2 109 0

ExpAA=5.70 First60=4.15 PredHel=0 Topology=i ps 20S proteasome regulatory subunit beta typ

1.9 103 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i ps ribosomal protein L9



4.7 317 Topology=i128-150o155-177i201-223o299-316i mosquito stringent pattern |transmembrane protein

ExpAA=75.93 First60=0.004PredHel=426.2 25.6 48.3 st Aegyptin uncharacterized

11.2 220 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o st putative salivary protein

. 159 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o st prefoldin subunit 6

0.9 209 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o st activated protein kinase C receptor

1.9 212 4 40.1 27.4 32.5 st

ExpAA=88.06 First60=15.29 PredHel=4 Topology=i46-68o99-121i134-156o183-202i serine/threonine specific protein phosphatas

6.7 133 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o st SGS5

3.6 302

ExpAA=10.35 First60=0.000PredHel=0 Topology=o st putative alpha-amylase

4 269 0

ExpAA=2.20 First60=0.01 PredHel=0 Topology=o st glycogen synthase kinase 3



20.1 196 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o tm mitochondrial ribosomal protein L49

3.7 107 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o tm salivary gland growth factor-2

5 313 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o tm unknown

5.2 302 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o tm putative 34 kDa secreted protein



7 198 4 41.9 7.6 50.5 tr

ExpAA=86.47 First60=41.84 PredHel=4 Topology=i9-26o36-58i70-92o97-119i putative 30 kDa allergen-like protein 30k-1

5.4 91 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o tr phosphatidylethanolamine-binding protein

7.1 208 Topology=i110-129o161-180i

ExpAA=41.38 First60=2.842PredHel=218.3 15.4 66.3 tr mitochondrial phosphate carrier protein

0.6 155 4 56.8 27.7 15.5 tr/vatpase

ExpAA=91.27 First60=43.84 PredHel=4 Topology=o4-26i38-60o90-112i124-146o vacuolar atpase 16kDa subunit

4 123 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o tr beta3-glucuronyltransferase

5.1 116 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i tr salivary gland protein

1.9 102 3 64.7 15.7 19.6 tr

ExpAA=61.95 First60=43.53 PredHel=3 Topology=i7-29o39-61i74-96o ferric reductase-like protein

0.9 224 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o tr ferritin light chain-like

4.9 301 Topology=o65-87i140-162o191-210i230-252o262-279i

ExpAA=99.43 First60=0.135PredHel=533.9 34.6 31.6 tr phosphatidylinositol transfer protein SEC14

4.3 298 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o tr Ag9 protein

9.3 244 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o tr salivary gland growth factor-2

3.9 300 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o tr serine protease



0.8 234 0

ExpAA=21.78 First60=12.54 PredHel=0 Topology=o uc hypothetical MTT-rich mucin

1.3 234

ExpAA=15.21 First60=8.430PredHel=0 Topology=o uc cathepsin L

9.3 148 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o uc bacteria-responsive protein 1 AgBR1

5.6 193 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o uc gSG1b salivary protein

6.8 115 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc chloride channel

2.7 252 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc putative salivary mucin 4

. 131 0

ExpAA=0.77 First60=0.44 PredHel=0 Topology=i uc salivary protein

6.5 106 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc putative 55.3 salivary protein

8 136 0

ExpAA=0.08 First60=0.07 PredHel=0 Topology=o uc 35.5 kDa salivary protein

6.8 232 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o uc 35.5 kDa salivary protein

5.8 170 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc salivary peroxidase

3.6 109 2 35.8 28.4 35.8

ExpAA=38.24 First60=17.31 PredHel=2 Topology=o28-45i84-106o ucm ribosomal protein L9

6.3 93 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc sg2 salivary protein

12.6 101 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc polyadenylate-binding protein

3.6 162 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc short form D7 salivary protein 3

6.8 145 1 15.2 30.3

ExpAA=31.73 First60=24.40 PredHel=1 Topology=o44-66i 54.5 ucm derlin 1

6 82 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i uc putative salivary protein

. 76 0

ExpAA=2.57 First60=2.57 PredHel=0 Topology=o uc vacuolar ATP synthase subunit F

4.5 154 3 39.6 24.7 35.7 uc

ExpAA=66.65 First60=21.03 PredHel=3 Topology=o25-47i60-77o90-112i conserved insect protein

1.3 78 1 28.2 56.4

ExpAA=21.51 First60=21.51 PredHel=1 Topology=i12-34o 15.4 uc salivary apyrase

1 102 1 18.6 4.9

ExpAA=19.50 First60=19.50 PredHel=1 Topology=o5-24i 76.5 uc ribosomal protein L4

3.1 126 1 17.5 36.5

ExpAA=22.67 First60=15.32 PredHel=1 Topology=o46-68i 46 uc unknown salivary protein

10 138 2 30.4 10.9 58.7

ExpAA=44.12 First60=39.89 PredHel=2 Topology=i7-27o42-64i uc histidine triad family zinc-binding protein

11 143 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc 71 kDa salivary protein

9.1 65 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc mitochondrial NADH-ubiquinone oxidoreduc

5.7 120 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc 30 kDa protein

5.1 193 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc conserved protein

2.4 122 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o uc membrane glycoprotein LIG-1

2.2 265 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o uc membrane glycoprotein LIG-1

2.8 177 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc unknown conserved protein

8.3 82 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i uc putative salivary secreted serine protease in

6.4 291 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o uc reverse transcriptase-like protein

4.1 143 0

ExpAA=0.13 First60=0.13 PredHel=0 Topology=i uc RAB family GTPase

Best

match to

% Match Best match to NR protein % Match KOG

E value % identity length database E value % identity length Species database E value









1E-145 84 91 long form D7clu12 salivary protein 1E-150 89 Uncharacterized conserved protein

0.53

91 Culex pipiens quinquefasciatus

1E-159 83 100 long form D7clu12 salivary protein 1E-164 87 100 Culex pipiens quinquefasciatus

1E-133 82 85 long form D7clu12 salivary protein 1E-139 87 Argininosuccinate lyase

0.97

85 Culex pipiens quinquefasciatus

1E-143 77 97 long form D7clu1 salivary protein 1E-140 77 dsRNA-activated protein kinase inhibito

0.041

97 Culex pipiens quinquefasciatus

1E-141 75 97 long form D7clu1 salivary protein 1E-138 75 dsRNA-activated protein kinase inhibito

0.21

97 Culex pipiens quinquefasciatus

1E-123 75 86 long form D7clu1 salivary protein 1E-120 75 dsRNA-activated protein kinase inhibito

0.068

86 Culex pipiens quinquefasciatus

6E-058 61 97 salivary short D7 protein 3 2E-058 65 97 Culex quinquefasciatus

2E-016 29 58 D7 protein, putative [Aedes aegypti]

5E-089 65 Exocyst complex subunit

82 Aedes aegypti 0.36

3E-010 28 74 3E-057 71

conserved hypothetical protein [Culex quinquefasciatus] Molecular chaperone

103 Culex quinquefasciatus 0.18 (DnaJ superfamil

2E-048 83 69 4E-050 95 Translational 0.65

general odorant-binding protein 99a [Culex quinquefasciatus] 69 Culex quinquefasciatus repressor Pumilio/PUF3 a



4E-053 68 71 salivary protein 2E-074 71 99 Uncharacterized conserved protein

0.008

Culex quinquefasciatus] quinquefasciatus

3E-055 55 101 salivary protein 7E-079 71 101 Uncharacterized conserved protein

3E-004

Culex quinquefasciatus] quinquefasciatus

2E-062 58 101 salivary protein 1E-078 71 101 Uncharacterized conserved protein

0.006

Culex quinquefasciatus] quinquefasciatus

5E-090 81 93 salivary protein 1E-108 91 100 RhoA GTPase 0.11effector

Culex pipiens quinquefasciatus DIA/Diaphanou

1E-092 82 93 salivary protein 1E-106 89 100 RhoA GTPase 0.11effector

Culex pipiens quinquefasciatus DIA/Diaphanou

4E-084 77 93 salivary protein 1E-109 91 100 RhoA GTPase 0.67effector

Culex pipiens quinquefasciatus DIA/Diaphanou

3E-023 41 42 30 kDa salivary gland allergen Aed3E-089

a 3 [Culex quinquefasciatus]

68 101 WD40 repeat 0.007

Culex quinquefasciatus nucleolar protein Bop1, in

3E-021 40 43 30 kDa salivary gland allergen Aed2E-091

a 3 [Culex quinquefasciatus]

70 102 Uncharacterized conserved protein

Culex quinquefasciatus 0.002



5E-014 62 45 8E-032

putative threonine-rich salivary mucin 60 83 Ca2+/Mg2+-permeable cation channel

0.025

Culex pipiens quinquefasciatus

2E-017 63 53 7E-039

putative threonine-rich salivary mucin 61 89 Host cell transcription

0.017

Culex pipiens quinquefasciatus factor HCFC1

2E-089 61 98 virus-induced RNA 1E-116 86 94 Uncharacterized conserved protein

0.002

Culex quinquefasciatus] quinquefasciatus

5E-060 86 47 salivary mucin 2E-056 86 26 Culex quinquefasciatus] quinquefasciatus





0.0 71 97 alpha-glucosidase 0.0 89 100 Alpha-amylaseE-113

1

Culex quinquefasciatus] quinquefasciatus

1E-108 60 56 alpha-glucosidase 1E-147 81 56 Alpha-amylaseE-039

7

Culex quinquefasciatus] quinquefasciatus

5E-037 50 29 alpha-amylase [Culex quinquefasciatus]

1E-074 89 29 Alpha-amylase

Culex quinquefasciatus 3E-054

1E-131 70 40 alpha-amylase I 1E-158 89 56 Alpha-amylaseE-097

9

Culex quinquefasciatus] quinquefasciatus

1E-66 53 25 alpha-amylase [Culex quinquefasciatus]

1E-118 92 45 Alpha-amylase

Culex quinquefasciatus 1E-083



2E-019 27 57 deoxyribonuclease I 1E-131 94 57 Culex quinquefasciatus] quinquefasciatus



1E-047 74 20 8E-046

alkaline phosphatase [Aedes aegypti] 62 Alkaline phosphatase

26 Aedes aegypti] aegypti 4E-023



0.001 35 18 serine protease htra2 [Aedes aegypti]5E-053 83 29 Serine protease

Aedes aegypti 2E-019

7E-46 35 78 elegaxobin-2 [Culex quinquefasciatus]1E-170 94 70 Trypsin

Culex quinquefasciatus 8E-043

3E-045 41 74 trypsin-like salivary secreted protein [Culex quinquefasciatus]

5E-086 61 83 Trypsin

Culex quinquefasciatus 2E-010

8E-011 30 17 serine protease 3E-046 82 21 Trypsin 1E-009

Culex quinquefasciatus] quinquefasciatus

2E-016 43 27 serine protease 9E-047 94 31 Trypsin 7E-018

Culex quinquefasciatus] quinquefasciatus

8E-023 49 35 serine protease [Aedes aegypti] 5E-047 79 Trypsin

42 Aedes aegypti 2E-022



2E-39 50 96 lysozyme [Culex quinquefasciatus]4E-079 91 100 Culex quinquefasciatus

1E-024 60 39 3E-028

salivary C-type lectin [Culex quinquefasciatus] 71 44 Culex quinquefasciatus

1E-141 77 79 1E-138 77

putative salivary Gram negative bacteria-binding protein 79 Aedes albopictus









1E-100 94 67 3E-097 94 67 Culex quinquefasciatus 2E-021 containing SCP

salivary secreted antigen-5 precursor AG5-3 [Culex quinquefasciatus] Defense-related protein

1E-050 61 53 venom allergen 5 3E-072 91 Defense-related protein containing SCP

1E-016

53 Culex quinquefasciatus] quinquefasciatus





2E-057 86 100 6E-059 93

salivary cysteine-rich peptide [Culex quinquefasciatus] Serine proteinase inhibitor (KU family)

100 Culex quinquefasciatus 0.24

2E-058 87 100 7E-060 94

salivary cysteine-rich peptide [Culex quinquefasciatus] Adhesion-type 0.21

100 Culex quinquefasciatus protein





1E-151 65 100 putative 41.9 kDa basic salivary protein

1E-159 69 RNA binding protein

0.30

100 Culex pipiens quinquefasciatus RBM12/SWAN





1E-117 83 100 putative 23.4 kDa salivary protein 1E-113 83 100 Culex pipiens quinquefasciatus



0.17 26 20 3E-012 28

conserved hypothetical protein [Culex quinquefasciatus] Vacuolar assembly/sorting protein VPS

69 Culex quinquefasciatus 0.62





2E-041 36 83 conserved hypothetical protein [Culex quinquefasciatus]

1E-112 82 88 Predicted alpha/beta

Culex quinquefasciatus 0.22 hydrolase BAT5

9E-035 33 79 [Culex 84

30.5 kDa secreted protein 30.5k-1 1E-107quinquefasciatus] 87 Culex quinquefasciatus

2E-035 34 79 [Culex 84

30.5 kDa secreted protein 30.5k-1 1E-107quinquefasciatus] 87 Culex quinquefasciatus

3E-034 33 79 [Culex 85

30.5 kDa secreted protein 30.5k-1 1E-107quinquefasciatus] 86 Culex quinquefasciatus

1E-033 33 79 [Culex 83

30.5 kDa secreted protein 30.5k-1 1E-107quinquefasciatus] 88 Culex quinquefasciatus

8E-026 34 61 [Culex 82

30.5 kDa secreted protein 30.5k-1 1E-079quinquefasciatus] 68 Culex quinquefasciatus



7E-009 34 67 putative 7.8 kDa secreted peptide 3E-005 34 67 Aedes albopictus



0.010 28 61

0.002 26 84

9E-004 31 98





2E-053 60 85 17.2 kDa salivary peptide 1E-072 76 101 Sulfide:quinone oxidoreductase/flavo-b

Culex quinquefasciatus 0.28

2E-055 57 97 17.2 kDa salivary peptide 1E-071 76 101 Sulfide:quinone oxidoreductase/flavo-b

Culex quinquefasciatus 0.29

6E-017 40 58 16.7 kDa salivary peptide 1E-045 76 70 Culex quinquefasciatus

5E-049 75 79 13.1 kDa salivary protein 5E-068 73 100 Culex quinquefasciatus

6E-015 28 93 1E-081

16 kDa salivary peptide [Culex quinquefasciatus] 86 98 Culex quinquefasciatus

4E-044 58 88 15.8 kDa salivary peptide 1E-047 59 101 Uncharacterized conserved protein

Culex quinquefasciatus 0.55

9E-040 50 87 16.7 kDa salivary peptide 1E-080 85 98 Culex quinquefasciatus

8E-031 59 63 15.8 kDa salivary peptide 9E-028 61 63 Culex quinquefasciatus

6E-042 54 81 17.5 kDa salivary peptide 1E-069 86 85 Culex quinquefasciatus

2E-033 48 87 16.7 kDa salivary peptide 2E-032 44 83 Culex quinquefasciatus

1E-032 48 87 16.7 kDa salivary peptide 3E-032 44 83 Culex quinquefasciatus

5E-031 45 87 16.7 kDa salivary peptide 1E-030 42 83 Culex quinquefasciatus

2E-025 39 86 16.7 kDa salivary peptide 1E-033 45 83 Culex quinquefasciatus

1E-025 39 86 16.7 kDa salivary peptide 2E-033 45 83 Culex quinquefasciatus

4E-013 32 76 4E-053

16.8 kDa salivary protein [Culex quinquefasciatus] 69 45 Culex quinquefasciatus

7E-015 41 68 16.8 kDa salivary peptide 9E-021 56 61 Culex quinquefasciatus

7E-027 44 75 16.7 kDa salivary peptide 1E-026 46 71 Culex quinquefasciatus

3E-028 54 53 putative 17.5 kDa salivary peptide 2E-024 54 53 Vesicle coat complex

0.17

Culex pipiens quinquefasciatus COPII, subunit S

2E-043 68 71 putative 16.3 kDa salivary peptide 1E-039 68 71 RNA polymerase III

0.28

Culex pipiens quinquefasciatus transcription factor

2E-030 46 85 16.7 kDa salivary peptide 3E-031 43 80 Culex quinquefasciatus



5E-031 82 62 4E-027

9.7 kDa salivary peptide [Culex quinquefasciatus] 82 62 Culex pipiens quinquefasciatus

0.049 24 79 kinase

Polynucleotide 0.28 3' phosphatase



putative GQP-rich salivary protein 3E-033 55 5'-3' exonuclease HKE1/RAT1

3E-004

100 Culex pipiens quinquefasciatus

putative GQP-rich salivary protein 5E-029 72 5'-3' exonuclease HKE1/RAT1

5E-005

61 Culex pipiens quinquefasciatus

putative GQP-rich salivary protein 5E-038 71 5'-3' exonuclease HKE1/RAT1

3E-005

78 Culex pipiens quinquefasciatus





1E-126 98 59 isoform

PREDICTED: similar to RE12057p1E-123 3 99 65 Actin and 1E-112

Nasonia vitripennis related proteins

1E-174 98 80 isoform

PREDICTED: similar to RE12057p1E-171 2 [Nasonia vitripennis]

99 80 Actin and 1E-151

Nasonia vitripennis related proteins

23 38 5 ribosomal protein L23a [Culex quinquefasciatus]

1E-100 93 84 60s ribosomal protein

Culex quinquefasciatus 1E-030 L23

0.095 28 21 troponin I [Culex quinquefasciatus]3E-043 87 41 Myosin class 0.002

Culex quinquefasciatus VI heavy chain

0.41 60 15 restin [Culex quinquefasciatus] 1E-119 90 60 Cytoskeleton-associated protein and re

Culex quinquefasciatus 1E-023

2.0 27 24 aegypti]

dynein light chain, putative [Aedes 4E-057 100 95 Dynein light chain

Aedes aegypti 7E-040



0.008 33 34 aggrecan core protein 5E-096 59 13 Muscarinic acetylcholine receptor

3E-004

Culex quinquefasciatus] quinquefasciatus

0.040 22 66 aggrecan core protein 3E-087 65 10 Myosin class I1E-004 chain

heavy

Culex quinquefasciatus] quinquefasciatus

0.22 22 26 AGAP005721-PA 8E-010 21 52 Chondroitin PEST] gambiae str. PEST

0.002

Anopheles gambiae str. 6-sulfotransferase and rela

9E-18 36 25 vitronectin [Culex quinquefasciatus] E-064

3 89 26 Gelatinase 1E-012

Culex quinquefasciatusA and related matrix metallo

5E-053 60 45 fasciclin [Culex quinquefasciatus] 3E-084 89 47 Culex quinquefasciatus

1E-061 84 41 annexin x [Culex quinquefasciatus]5E-064 94 41 Annexin

Culex quinquefasciatus 1E-040



0.26 25 20 Sptzle 1B [Culex quinquefasciatus]2E-038 80 30 Culex quinquefasciatus



1E-053 66 49 7E-076

kynurenine formamidase [Culex quinquefasciatus] 92 Kynurenine 2E-011

50 Culex quinquefasciatus formamidase

0.37 25 37 1E-139 86

aminopeptidase 2, mitochondrial [Culex quinquefasciatus] Puromycin-sensitive

31 Culex quinquefasciatus 3E-031aminopeptidase a

4.0 37 9 6E-070 98

DNA-directed RNA polymeraseI [Culex quinquefasciatus] RNA polymerase subunit K

100 Culex quinquefasciatus 8E-041

0.097 25 34 6E-064 81

conserved hypothetical protein [Culex quinquefasciatus] Leucine-rich 0.006

31 Culex quinquefasciatus repeat protein

2.1 40 6 2E-048 88

conserved hypothetical protein [Culex quinquefasciatus] Uncharacterized conserved protein

44 Culex quinquefasciatus 0.41

2.7 53 3 6E-056

glutamate carboxypeptidase [Culex quinquefasciatus] 98 Metalloexopeptidases

22 Culex quinquefasciatus 5E-041

0.053 35 17 [Culex 97

threonine dehydratase/deaminase 6E-078quinquefasciatus] Threonine/serine dehydratases

32 Culex quinquefasciatus 2E-038

0.66 43 9 1E-156 94 Aminomethyl transferase

aminomethyltransferase, mitochondrial [Culex quinquefasciatus] 70 Culex quinquefasciatus 6E-098

0.056 32 25 4E-039 88 36 Culex

ezrin-radixin-moesin-binding phosphoprotein 50 [Culex quinquefasciatus] quinquefasciatus



0.98 41 12 0.0

deltamethrin resistance-associated NYD-GBE [Culex95 47 Culex 1,4-alpha-glucan branching enzyme/sta

quinquefasciatus] quinquefasciatus 1E-104

0.34 31 12 quinquefasciatus]86

hydroxypyruvate isomerase [Culex1E-105 Hydroxypyruvate isomerase

80 Culex quinquefasciatus 5E-062

2.5 27 28 1E-112

galactokinase [Culex quinquefasciatus] 87 Galactokinase

60 Culex quinquefasciatus 3E-023

0.62 34 15 6-phosphogluconolactonase [Aedes aegypti]

5E-081 80 6-phosphogluconolactonase - like prote

73 Aedes aegypti 3E-046

3E-033 31 55 1E-156 88

UDP-glucuronosyltransferase 1-1 [Culex quinquefasciatus] UDP-glucuronosyl and

59 Culex quinquefasciatus 2E-021 UDP-glucosyl tr

2.3 25 18 4E-082 98 UDP-glucose 3E-067

utp-glucose-1-phosphate uridylyltransferase 2 [Aedes aegypti] 30 Aedes aegypti pyrophosphorylase

1.0 29 13 3E-049 97

conserved hypothetical protein [Culex quinquefasciatus] Glyceraldehyde 3-phosphate dehydrog

30 Culex quinquefasciatus 3E-018

0.56 27 18 importin [Culex quinquefasciatus] 1E-116 98 Nuclear transport receptor LGL2 (impo

21 Culex quinquefasciatus 2E-029



0.30 23 28 1E-124 97 NAD-dependent malate

mitochondrial malate dehydrogenase 2 [Culex quinquefasciatus] 70 Culex quinquefasciatus 6E-098 dehydrogenas

1.5 32 14 1E-055

lethal 35Di [Culex quinquefasciatus] 97 NADH:ubiquinone oxidoreductase, ND

64 Culex quinquefasciatus 2E-023

0.12 36 17 1E-147 97

3-hydroxyacyl-coa dehyrogenase [Culex quinquefasciatus] 3-hydroxyacyl-CoA dehydrogenase

89 Culex quinquefasciatus 1E-100

1E-059 97 23 ATP synthase beta subunit [Aedes5E-056

aegypti] 97 F0F1-type ATP synthase, beta subunit

23 Aedes aegypti 5E-057

1E-156 92 61 ATP synthase beta subunit [Aedes1E-164

aegypti] 97 F0F1-type ATP synthase, beta subunit

61 Aedes aegypti 1E-167

2.4 45 9 1E-148 95 64 Culex quinquefasciatus 3E-046 c reductase, sub

Ubiquinol cytochrome

ubiquinol-cytochrome c reductase complex core protein [Culex quinquefasciatus]

0.18 28 21 1E-085 97 Mitochondrial F1F0-ATP synthase, sub

ATP synthase B chain, mitochondrial [Culex quinquefasciatus] 68 Culex quinquefasciatus 8E-038

2E-041 83 15 8E-041

malic enzyme [Culex quinquefasciatus] 94 NADP+-dependent malic enzyme

13 Culex quinquefasciatus 4E-025

1E-163 89 53 1E-173

malic enzyme [Culex quinquefasciatus] 97 NADP+-dependent malic enzyme

47 Culex quinquefasciatus 1E-151

8E-064 95 100 6E-062 98 Mitochondrial F1F0-ATP synthase, sub

mitochondrial ATP synthase F chain [Culex quinquefasciatus] 100 Culex quinquefasciatus 3E-034

7E-048 83 100 3E-052 93 [Culex Protein farnesyltransferase, alpha subu

mitochondrial NADH-ubiquinone oxidoreductase AGGG subunit100 Culex quinquefasciatus 0.92

0.31 36 17 2E-072 97 Mitochondrial F1F0-ATP synthase, sub

ATP synthase B chain, mitochondrial [Culex quinquefasciatus] 58 Culex quinquefasciatus 2E-029

0.092 40 10 1E-118 83

conserved hypothetical protein [Culex quinquefasciatus] Transcription 0.014

48 Culex quinquefasciatus factor, Myb superfamily

1.7 30 8 1E-107 90 73 F0F1-type ATP synthase, gamma subu

ATP synthase gamma chain, mitochondrial [Culex quinquefasciatus]Culex quinquefasciatus 2E-075

1E-055 68 88 4E-074 91 90 Culex quinquefasciatus import inner membrane t

mitochondrial NADH:ubiquinone oxidoreductase B14.7 subunit [Culex Mitochondrial 0.087

1E-125 92 87 40S ribosomal protein S2 [Aedes aegypti]

1E-132 99 40S 3E-098

87 Aedes aegypti ribosomal protein S2/30S ribosom

1E-037 77 29 2E-096

ribosomal protein S6 [Aedes aegypti] 83 40S ribosomal protein

67 Aedes aegypti] aegypti 4E-020 S6

2E-004 31 26 9E-095

hexokinase [Culex quinquefasciatus] 98 Hexokinase

39 Culex quinquefasciatus 1E-052

6.9 35 7 9E-094 90 43 Culex quinquefasciatus 2E-021 c reductase, sub

Ubiquinol cytochrome

ubiquinol-cytochrome c reductase complex core protein [Culex quinquefasciatus]

0.56 36 1 AGAP012048-PA 2E-079 97 Citrate synthase

5E-058

31 Anopheles gambiae str. PEST] gambiae str. PEST

3E-006 27 44 ATP-citrate synthase 0.0 98 ATP-citrate quinquefasciatus

1E-136

29 Culex quinquefasciatus]lyase

1E-025 87 77 AGAP006630-PA 8E-022 85 77 Anopheles gambiae str. PEST] gambiae str. PEST



1E-146 83 76 1E-162

3-ketoacyl-CoA thiolase [Culex quinquefasciatus] 96 Acetyl-CoA 1E-125

76 Culex quinquefasciatus acetyltransferase

0.17 44 16 peroxiredoxin-4 2E-074 99 Alkyl hydroperoxide reductase,

1E-063

54 Culex quinquefasciatus] quinquefasciatus thiol sp

0.74 20 36 1E-143

endoU protein [Culex quinquefasciatus] 96 Placental protein 11

46 Culex quinquefasciatus 9E-069



6E-024 34 54 1E-134 99

trifunctional enzyme beta subunit [Culex quinquefasciatus] Acetyl-CoA 1E-120

51 Culex quinquefasciatus acetyltransferase

5.2 30 13 1E-142 94 Animal-type 2E-063

fatty acid synthase S-acetyltransferase [Culex quinquefasciatus] 11 Culex quinquefasciatus fatty acid synthase and rel

1.7 32 13 1E-145 94 60 Culex quinquefasciatus 1E-108

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [Culex Branched chain alpha-keto acid dehyd

0.95 44 21 4E-076 97

conserved hypothetical protein [Culex quinquefasciatus] Long-chain 1E-025

22 Culex quinquefasciatus acyl-CoA synthetases (AM

2.8 26 28 saposin [Culex quinquefasciatus] 1E-118 95 Prosaposin

21 Culex quinquefasciatus 1E-011

0.52 32 27 1E-056 94 Mitochondrial glycerol-3-phosphate acy

glycerol-3-phosphate acyltransferase [Culex quinquefasciatus] 14 Culex quinquefasciatus 7E-015



3.0 46 6 [Culex 96

purine biosynthesis protein 6, pur61E-146 quinquefasciatus] Phosphoribosylamidoimidazole-succino

62 Culex quinquefasciatus 4E-040

0.74 20 36 1E-143

endoU protein [Culex quinquefasciatus] 96 Placental protein 11

46 Culex quinquefasciatus 9E-069

1E-040 62 41 4E-060

kynurenine formamidase [Culex quinquefasciatus] 90 Kynurenine 3E-007

42 Culex quinquefasciatus formamidase



0.053 31 10 PREDICTED: similar to Hist1h4c protein

2E-048 100 49 Histone H4 2E-036

Equus caballus

3E-041 66 78 aegypti]

40S ribosomal protein S10 [Aedes 3E-056 85 80 40s protein

Aedes aegypti ribosomal1E-027 s10

23 35 4 anamorsin [Culex quinquefasciatus]

3E-062 94 47 Protein DRE2, required

Culex quinquefasciatus 1E-029 for cell viability

2.6 25 3 maintenance of ploidy protein mob1 [Culex quinquefasciatus]

1E-113 97 91 Cell cycle-associated

Culex quinquefasciatus 3E-099 protein



0.39 38 14 clathrin light chain 2E-087 96 67 Vesicle coat quinquefasciatus

3E-029

Culex quinquefasciatus] protein clathrin, light chain

3E-016 39 51 ras-related protein Rab-7 [Culex quinquefasciatus]

5E-082 99 71 Ras-related 2E-056

Culex quinquefasciatus GTPase

1.8 23 17 coatomer subunit epsilon [Culex quinquefasciatus]

1E-153 97 91 Vesicle coat 2E-069

Culex quinquefasciatus complex COPI, epsilon su

1.8 23 17 coatomer subunit epsilon [Culex quinquefasciatus]

1E-155 97 92 Vesicle coat 1E-069

Culex quinquefasciatus complex COPI, epsilon su

0.10 20 30 AP-2 complex subunit mu [Culex quinquefasciatus]

8E-059 98 39 Clathrin-associated protein medium ch

Culex quinquefasciatus 6E-028

0.54 40 10 quinquefasciatus]93

nuclear RNA export factor 2 [Culex7E-042 mRNA export 0.001

12 Culex quinquefasciatus factor TAP/MEX67

0.60 21 15 [Culex 90

glutathione-s-transferase theta, gst5E-053 quinquefasciatus] Glutathione 4E-014

51 Culex quinquefasciatus S-transferase

0.32 26 13 1E-135 97 86 Culex quinquefasciatus 8E-073 complex TRAP

translocon-associated protein subunit alpha [Culex quinquefasciatus] Translocon-associated



5E-055 40 75 mast cell protease 3 1E-146 90 Trypsin 4E-050

92 Culex quinquefasciatus] quinquefasciatus

4E-059 84 20 3E-068

78 kDa glucose-regulated protein [Culex quinquefasciatus]97 Molecular chaperones

20 Culex quinquefasciatus 2E-047 GRP78/BiP/KAR

1E-158 92 46 1E-166

78 kDa glucose-regulated protein [Culex quinquefasciatus]99 Molecular chaperones

46 Culex quinquefasciatus 1E-144 GRP78/BiP/KAR

7.4 35 6 [Culex 96

NEDD4 family-interacting protein 11E-087 quinquefasciatus] Golgi-associated protein/Nedd4 WW d

71 Culex quinquefasciatus 1E-040

0.45 26 3 1E-107

conserved hypothetical protein [Culex quinquefasciatus] 87 Cellular repressor of

83 Culex quinquefasciatus 7E-045transcription

0.41 28 15 9E-094

conserved hypothetical protein [Culex quinquefasciatus] 98 Uncharacterized conserved protein

77 Culex quinquefasciatus 2E-050

7E-093 76 99 1E-117

elongation factor 1-beta [Culex quinquefasciatus] 95 Elongation 6E-073

100 Culex quinquefasciatusfactor 1 beta/delta chain

8E-011 29 32 cathepsin l [Culex quinquefasciatus] 1E-068 96 Cysteine proteinase

23 Culex quinquefasciatus 8E-025Cathepsin L

1E-095 92 40 2E-096

disulfide-isomerase A6 [Culex quinquefasciatus] 95 42 Culex quinquefasciatus

0.55 36 10 prefoldin [Culex quinquefasciatus] 2E-049 95 Molecular chaperone

78 Culex quinquefasciatus 8E-016 Prefoldin, subuni

0.53 33 14 1E-113 99 29 Culex Translation 1E-064

eukaryotic translation initiation factor 3 subunit 9 [Culex quinquefasciatus] quinquefasciatus initiation factor 3, subunit b

2.1 34 36 3E-049 97

rhomboid protein 1, mitochondrial [Culex quinquefasciatus] Integral membrane protease of the rho

26 Culex quinquefasciatus 8E-018

1E-094 95 100 peptidyl-prolyl cis-trans isomerase 2E-091

f, ppif [Aedes aegypti]

94 Cyclophilin type peptidyl-prolyl cis-tran

82 Aedes aegypti 4E-069

1.2 28 42 slender lobes [Culex quinquefasciatus]1E-109 87 RNA binding 0.067

21 Culex quinquefasciatus protein RBM12/SWAN

0.055 60 5 3E-099 97 Glycosyltransferase

alpha-1,2-mannosyltransferase alg11 [Culex quinquefasciatus] 38 Culex quinquefasciatus 4E-056

0.001 23 35 6E-064

AH receptor-interacting protein [Culex quinquefasciatus] 97 Aryl-hydrocarbon receptor-interacting p

39 Culex quinquefasciatus 8E-038



0.0 98 82 26S protease regulatory subunit S10B [Culex quinquefasciatus]

1E-179 98 82 26S proteasome regulatory complex, A

Culex quinquefasciatus 1E-150

7E-045 40 52 26S protease regulatory subunit 8 [Culex quinquefasciatus]

1E-145 99 66 26S proteasome regulatory complex, A

Culex quinquefasciatus 1E-135

1E-051 74 83 7E-071

ubiquitin (ribosomal protein L40) [Aedes aegypti] 100 83 Ubiquitin/40S ribosomal

Culex quinquefasciatus 2E-048 protein S27a f

0.026 31 38 LD06566p [Culex quinquefasciatus] 2E-061 96 11 Ubiquitin protein ligase

Culex quinquefasciatus 2E-025 RSP5/NEDD4

5E-040 79 40 proteasome subunit beta type 6 [Culex quinquefasciatus]

1E-053 97 47 20S proteasome, regulatory subunit be

Culex quinquefasciatus 1E-030



0.54 37 5 2E-088 95 53 Culex quinquefasciatus 1E-054

multisynthetase complex auxiliary component p43 [Culex quinquefasciatus] tRNA-binding protein

4.0 31 17 1E-120

40S ribosomal protein S3 [Culex quinquefasciatus] 99 40S ribosomal protein

88 Culex quinquefasciatus 8E-096 S3

1.2 26 9 1E-160

histidyl-tRNA synthetase [Culex quinquefasciatus] 96 Histidyl-tRNA synthetase

57 Culex quinquefasciatus 1E-125

3E-047 75 65 60S ribosomal protein L35a [Culex9E-055 quinquefasciatus]99 60S ribosomal protein

72 Culex quinquefasciatus 7E-030 L35A/L37

6E-096 94 65 5E-095

60S ribosomal protein L7 [Culex quinquefasciatus] 97 60S ribosomal protein

65 Culex quinquefasciatus 5E-054 L7

0.084 40 7 3E-049 97 Transcription elongation

transcription elongation factor SPT4 [Culex quinquefasciatus] 78 Culex quinquefasciatus 1E-035 factor SPT4

3E-028 31 71 1E-126

ribosome production factor 1 [Culex quinquefasciatus] 96 Ribosome biogenesis

62 Culex quinquefasciatus 9E-068 protein RPF1, co

0.54 28 13 3E-087 92 Mitochondrial ribosomal

mitochondrial ribosomal protein, S35 [Culex quinquefasciatus] 51 Culex quinquefasciatus 8E-039 protein S28

4E-080 95 82 60S ribosomal protein L18a [Aedes aegypti]

3E-077 96 60S 9E-056

98 Aedes aegypti ribosomal protein L18A

2E-083 91 79 2E-085

40S ribosomal protein S8 [Culex quinquefasciatus] 98 40S ribosomal protein

79 Culex quinquefasciatus 2E-059 S8

3E-087 89 36 6E-088

elongation factor 1-gamma [Culex quinquefasciatus] 95 Translation 9E-061

36 Culex quinquefasciatus elongation factor EF-1 gam

5E-039 96 65 1E-048

ribosomal protein S25 [Culex quinquefasciatus] 98 40S ribosomal protein

82 Culex quinquefasciatus 4E-030 S25

2E-040 95 68 1E-046

ribosomal protein S25 [Culex quinquefasciatus] 98 40S ribosomal protein

79 Culex quinquefasciatus 3E-028 S25

4E-070 96 31 1E-075

60S ribosomal protein L3 [Culex quinquefasciatus] 98 60S ribosomal protein

32 Culex quinquefasciatus 5E-045 L3 and related p

0.35 35 24 1E-146

conserved hypothetical protein [Culex quinquefasciatus] 95 Thyroid hormone receptor-associated p

20 Culex quinquefasciatus 0.010

1E-118 90 76 1E-126

60S ribosomal protein L5 [Culex quinquefasciatus] 98 60S ribosomal protein

76 Culex quinquefasciatus 2E-060 L5

0.087 39 7 1E-086

conserved hypothetical protein [Culex quinquefasciatus] 93 Structural maintenance of chromosome

65 Culex quinquefasciatus 0.79

0.060 26 59 1E-117 91 Mitochondrial ribosomal

mitochondrial ribosomal protein, L46 [Culex quinquefasciatus] 87 Culex quinquefasciatus 5E-041 protein L17

1E-068 99 66 40S ribosomal protein S9 [Aedes aegypti]

2E-071 97 Ribosomal protein S4

72 Aedes aegypti 2E-047

1E-081 85

translation initiation factor if-2 [Culex quinquefasciatus] Translation 6E-007

19 Culex quinquefasciatus initiation factor 5B (eIF-5B)

1.2 31 17 3E-089

40S ribosomal protein S3 [Culex quinquefasciatus] 99 40S ribosomal protein

66 Culex quinquefasciatus 3E-068 S3

1E-104 100 68 1E-113

60S ribosomal protein L8 [Culex quinquefasciatus] 100 60s ribosomal protein

76 Culex quinquefasciatus 2E-084 L2/L8

0.69 31 13 elongation factor 2 1E-172 98 Elongation factor 2

1E-166

29 Culex quinquefasciatus] quinquefasciatus

1.5 34 11 1E-087

conserved hypothetical protein [Culex quinquefasciatus] 98 40S ribosomal protein

85 Culex quinquefasciatus 5E-060 S7

7E-074 86 100 6E-083

40s ribosomal protein s19 [Culex quinquefasciatus] 100 40S ribosomal protein

100 Culex quinquefasciatus 4E-055 S19

8E-073 85 100 7E-082

40s ribosomal protein s19 [Culex quinquefasciatus] 98 40S ribosomal protein

100 Culex quinquefasciatus 8E-055 S19

1E-052 97 88 ribosomal protein L36, putative [Aedes aegypti]

3E-049 97 60S 3E-018

88 Aedes aegypti ribosomal protein L36

8E-062 98 100 ribosomal protein L36, putative [Aedes aegypti]

4E-058 98 60S 6E-024

100 Aedes aegypti ribosomal protein L36

1E-100 97 100 9E-098

60S ribosomal protein L18a [Aedes aegypti] 98 60S ribosomal protein

100 Culex quinquefasciatus 2E-068 L18A

2E-040 83 100 60S ribosomal protein L37a [Culex2E-045 100

quinquefasciatus] 60S ribosomal protein

100 Culex quinquefasciatus 2E-029 L37

2E-048 97 100 5E-045

40S ribosomal protein S27 [Culex quinquefasciatus] 98 40s ribosomal protein

55 Culex quinquefasciatus 3E-032 S27

2E-084 71 100 1E-116

vacuolar ATP synthase subunit e [Culex quinquefasciatus] 96 Vacuolar H+-ATPase

100 Culex quinquefasciatus 9E-068 V1 sector, subun

1E-121 91 99 1E-124

60S ribosomal protein L10 [Culex quinquefasciatus] 97 60s ribosomal protein

100 Culex quinquefasciatus 1E-080 L10

5E-006 100

Ribosomal protein L41 CG30425-PA [Drosophila melanogaster]100 Triatoma infestans] gambiae str. PEST

1.4 47 6 5E-052 98 100 Ca2+ release 0.79

hypothetical protein CpipJ_CPIJ008169 [Culex quinquefasciatus] Culex quinquefasciatus channel (ryanodine rece

0.025 33 65 9E-068

40S ribosomal protein S30 [Culex quinquefasciatus] 98 Ubiquitin-like/40S ribosomal S30 prote

100 Culex quinquefasciatus 3E-019

1E-043 97 49 5E-051

ribosomal protein S16 [Culex quinquefasciatus] 99 40S ribosomal protein

70 Culex quinquefasciatus 1E-046 S16

0.15 18 31 1E-086 89 Mitochondrial ribosomal

mitochondrial ribosomal protein, S35 [Culex quinquefasciatus] 52 Culex quinquefasciatus 4E-039 protein S28

6E-095 92 87 1E-105

40S ribosomal protein S8 [Culex quinquefasciatus] 99 40S ribosomal protein

95 Culex quinquefasciatus 3E-071 S8

1E-063 81 71 5E-077

ribosomal protein L19 [Culex quinquefasciatus] 100 60s ribosomal protein

71 Culex quinquefasciatus 9E-032 L19

2E-056 89 71 4E-055

60S ribosomal protein L15 [Culex quinquefasciatus] 94 60s ribosomal protein

71 Culex quinquefasciatus 9E-033 L15/L27

2E-040 32 71 elongation factor Tu 1E-167 100 Mitochondrial 1E-149

translation elongation fac

64 Culex quinquefasciatus] quinquefasciatus

1E-109 75 89 1E-134

40S ribosomal protein SA [Culex quinquefasciatus] 93 40S ribosomal protein

91 Culex quinquefasciatus 1E-071 SA (P40)/Lamin

0.031 42 13 1E-037

conserved hypothetical protein [Culex quinquefasciatus] 70 49 Culex quinquefasciatus

1.9 30 21 gryzun [Culex quinquefasciatus] 5E-091 88 Uncharacterized conserved protein

14 Culex quinquefasciatus 1E-009

9E-057 97 85 9E-055

60S ribosomal protein L31 [Culex quinquefasciatus] 99 60S ribosomal protein

85 Culex quinquefasciatus 2E-030 L31

5E-051 85 39 4E-054 97 39 Culex Translation 3E-029

eukaryotic translation initiation factor 3 subunit 5 [Culex quinquefasciatus] quinquefasciatus initiation factor 3, subunit f

2E-018 93 29 8E-040

60S ribosomal protein L24 [Culex quinquefasciatus] 96 60s ribosomal protein

80 Culex quinquefasciatus 4E-004 L24

5E-080 90 57 2E-082

40S ribosomal protein S3a [Culex quinquefasciatus] 98 40S ribosomal protein

41 Culex quinquefasciatus 9E-048 S3A

1.3 37 21 amidase [Culex quinquefasciatus] 4E-056 97 Amidases

20 Culex quinquefasciatus 8E-027

8E-052 94 54 60S ribosomal protein L9 [Aedes aegypti]

5E-048 94 60S 2E-021

54 Aedes aegypti ribosomal protein L9



0.19 26 15 1E-178 97 type [Culex Ca2+ transporting ATPase

calcium-transporting atpase sarcoplasmic/endoplasmic reticulum32 Culex quinquefasciatus 1E-146

0.61 34 21 0.51

Phosphatidylinositol 3-phosphate 3-pho

0.020 27 76 LRR Toll [Culex quinquefasciatus] 2E-052 68 Cytoplasmic 0.006

51 Culex quinquefasciatus Zn-finger protein BRAP2 (

3E-009 23 53 subunit 98 61 Culex G-protein beta subunit

guanine nucleotide-binding protein1E-116 beta 1 [Culex quinquefasciatus]quinquefasciatus 4E-095

1.3 27 13 GPR89A [Culex quinquefasciatus] 1E-117 98 Predicted G-protein coupled receptor

47 Culex quinquefasciatus 4E-085

0.074 29 3 8E-072 98 Carnitine O-acyltransferase CRAT

5'-AMP-activated protein kinase catalytic subunit alpha-2 [Culex 24 Culex quinquefasciatus 0.16

0.24 27 12 1E-171 97 51 Putative phosphoinositide phosphatase

recessive suppressor of secretory defect [Culex quinquefasciatus] Culex quinquefasciatus 1E-106

7E-013 25 49 tyrosine kinase receptor [Aedes aegypti]

1E-152 97 Fibroblast/platelet-derived growth facto

38 Aedes aegypti 4E-079



2.6 31 25 hypothetical protein AaeL_AAEL005358 [Aedes aegypti]

4E-076 73 Inositol-1,4,5-triphosphate 5-phosphata

52 Aedes aegypti 7E-004

6.1 28 5 7E-055 quinquefasciatus]

transcription initiation factor TFIID subunit 12 [Culex100 Transcription initiation

61 Culex quinquefasciatus 7E-041 factor TFIID, sub

1.6 28 25 1E-168

conserved hypothetical protein [Culex quinquefasciatus] 92 Predicted ATP-dependent protease PIL

56 Culex quinquefasciatus 2E-021

2.0 37 11 nucleolar GTP-binding protein [Aedes aegypti]

1E-153 90 GTP-binding protein CRFG/NOG1 (OD

46 Aedes aegypti 1E-066



0.89 64 7 1E-103 96

monocarboxylate transporter [Culex quinquefasciatus] Monocarboxylate transporter

25 Culex quinquefasciatus 8E-025

9E-049 93 43 protein 96 76 Culex quinquefasciatus 3E-031

phosphatidylethanolamine-binding 3E-046 2 [Culex quinquefasciatus] Phosphatidylethanolamine binding prot

1E-105 88 59 PfmpC [Culex quinquefasciatus] 1E-114 97 Mitochondrial phosphate carrier protein

59 Culex quinquefasciatus 2E-099

3E-015 29 95 1E-079 99 75 Culex quinquefasciatus 8E-045 V0 sector, subun

vacuolar ATP synthase 21 kDa proteolipid subunit [Culex quinquefasciatus] Vacuolar H+-ATPase

3.6 62 5 6E-061 95

ATP-binding cassette transporter [Culex quinquefasciatus] 12 Culex quinquefasciatus

0.85 47 9 4E-057

vitellogenin-A1 [Culex quinquefasciatus] 90 Endonuclease 0.47

5 Culex quinquefasciatus MUS81

3.3 26 29 2E-053 96 17 Culex quinquefasciatus 4E-022

Sodium-neurotransmitter symporter

sodium/chloride dependent neurotransmitter transporter [Culex quinquefasciatus]

1E-023 31 105 ferritin light-chain 1E-121 97 100 Ferritin 2E-011

Culex quinquefasciatus] quinquefasciatus

1.2 24 24 1E-169

na+/k+ atpase alpha subunit [Aedes aegypti] 96 30 Na+/K+ ATPase, alpha subunit

Aedes aegypti 1E-158

1.5 26 18 apolipophorins [Culex quinquefasciatus]

1E-164 96 9 WD40 repeat-containing protein

Culex quinquefasciatus 0.45

0.91 28 8 1E-133 93

polymerase delta-interacting protein 2 [Culex quinquefasciatus] 64 Putative Mg2+ and Co2+ transporter C

Culex quinquefasciatus 3E-085

0.53 25 25 vitellogenin C2 1E-159 90 15 Predicted RNA binding

5E-006

Culex pipiens quinquefasciatus protein, contain



0.86 25 56 conserved hypothetical protein [Culex quinquefasciatus]

1E-128 96 56 Uncharacterized conserved protein

Culex quinquefasciatus 2E-028

4.2 27 11 conserved hypothetical protein [Culex quinquefasciatus]

1E-126 94 56 Uncharacterized conserved protein

Culex quinquefasciatus 1E-027

0.34 31 12 conserved hypothetical protein [Culex quinquefasciatus]

2E-061 79 76 Uncharacterized protein PSP1 (suppre

Culex quinquefasciatus 0.11

0.86 34 11 conserved hypothetical protein [Culex quinquefasciatus]

4E-096 91 28 WD40 repeat protein

Culex quinquefasciatus 2E-009

0.64 20 18 conserved hypothetical protein [Culex quinquefasciatus]

5E-062 100 40 Nicotinic acid phosphoribosyltransferas

Culex quinquefasciatus 2E-009

1E-020 22 45 1E-020

hypothetical protein AaeL_AAEL003100 [Aedes aegypti] 24 45 Myosin class II0.007 chain

Aedes aegypti heavy

2E-12 25 38 6E-054 81

conserved hypothetical protein [Culex quinquefasciatus] 37 Culex quinquefasciatus

2.1 27 8 conserved hypothetical protein [Culex quinquefasciatus]

3E-054 95 26 Lipoate-protein ligase

Culex quinquefasciatus 1E-010 A

0.86 50 6 conserved hypothetical protein [Culex quinquefasciatus]

2E-066 93 54 Beta, beta-carotene

Culex quinquefasciatus 0.14 15,15'-dioxygenas

1.9 50 6 conserved hypothetical protein [Culex quinquefasciatus]

1E-114 90 94 Beta, beta-carotene

Culex quinquefasciatus 0.44 15,15'-dioxygenas

0.42 31 13 ZNF403 [Culex quinquefasciatus] 2E-071 80 28 Culex quinquefasciatus

2.2 25 24 2E-055

transmembrane protein 19 [Culex quinquefasciatus] 94 33 Predicted membrane

Culex quinquefasciatus 1E-030 protein

2.0 28 31 conserved hypothetical protein [Culex quinquefasciatus]

3E-048 97 37 Zn-finger transcription

Culex quinquefasciatus 0.29 factor

16 72 2 conserved hypothetical protein [Culex quinquefasciatus]

3E-051 99 22 Myosin class 0.18

Culex quinquefasciatus I heavy chain

4.3 28 42 isochorismatase domain-containing protein 2, mitochondrial [Culex

3E-083 95 81 Mitochondrial associated endoribonucl

Culex quinquefasciatus 2E-053

2E-058 82 50 derlin-2.1 [Culex quinquefasciatus]7E-076 94 56 Predicted membrane

Culex quinquefasciatus 2E-025 protein

2E-031 72 54 salivary protein 5E-028 73 55 Culex quinquefasciatus

0.55 38 27 8E-030 85

hypothetical protein CpipJ_CPIJ017044 [Culex quinquefasciatus] 100 Culex quinquefasciatus

7E-066 80 101 2E-074

conserved insect protein [Culex quinquefasciatus] 93 100 Culex quinquefasciatus

0.32 24 15 3E-031 93

hypothetical protein CpipJ_CPIJ017043 [Culex quinquefasciatus] 101 Culex quinquefasciatus

0.046 34 11 1E-045 90

conserved hypothetical protein [Culex quinquefasciatus] 102 Culex quinquefasciatus

0.44 35 17 1E-054

hypothetical protein AaeL_AAEL014318 [Aedes aegypti] 87 24 Aedes aegypti

0.52 47 13 conserved hypothetical protein [Culex quinquefasciatus]

1E-070 95 100 Membrane-associated

Culex quinquefasciatus 0.013 protein tyrosine

2.7 22 6 conserved hypothetical protein [Culex quinquefasciatus]

3E-073 97 31 Calsyntenin

Culex quinquefasciatus 0.56

3E-032 89 63 3E-029 93

conserved hypothetical protein [Culex quinquefasciatus] 63 Culex quinquefasciatus

0.11 25 34 conserved hypothetical protein [Culex quinquefasciatus]

4E-051 88 9 Focal adhesion protein

Culex quinquefasciatus 0.51 Tensin, contain

3E-039 69 62 coiled-coil domain-containing protein 124 [Culex quinquefasciatus]

6E-094 92 91 Uncharacterized conserved protein

Culex quinquefasciatus 2E-023

0.064 25 11 conserved hypothetical protein [Culex quinquefasciatus]

1E-045 80 35 Protein kinase 0.81

Culex quinquefasciatus ATM/Tel1, involved in te

6E-016 25 58 conserved hypothetical protein [Culex quinquefasciatus]

1E-119 81 77 Membrane 1E-004

Culex quinquefasciatusglycoprotein LIG-1

2E-083 83 52 conserved hypothetical protein [Culex quinquefasciatus]

9E-090 92 61 Uncharacterized conserved protein

Culex quinquefasciatus 8E-030

0.42 34 38 conserved hypothetical protein [Culex quinquefasciatus]

2E-042 90 22 Tyrosine kinase, EPH

Culex quinquefasciatus 0.49 (ephrin) receptor

0.003 34 18 conserved hypothetical protein 1E-030 60 60 Predicted C3H1-type

Culex quinquefasciatus 0.006 Zn-finger protein

1E-074 94 67 conserved hypothetical protein [Culex quinquefasciatus]

8E-072 95 67 GTPase Rab11/YPT3,

Culex quinquefasciatus 5E-049 small G protein

Best Best Best Best Best

match to match to match to match to match to

General GO CDD All CDD PFAM SMART COG

class database E value database E value domains database E value database E value database









Function unknown PhBP 0.64 PhBP | PBP_GOBP 0.49 PhBP 0.007

PhBP PBP_GOBP 0.40 PhBP

0.018 PhBP 0.018| 2E-004

Amino acid transport and metabolism PhBP 0.44 PhBP | PBP_GOBP 0.46 PhBP 0.005

Defense mechanisms PhBP PBP_GOBP 0.018

0.009 PhBP 0.009| PBP_GOBP 0.067| PhBP 1E-004 LasB, Zinc metalloprotease (elastas

Defense mechanisms PhBP PBP_GOBP 0.027

0.005 PhBP 0.005| PBP_GOBP 0.099| PhBP 5E-005

Defense mechanisms PhBP PBP_GOBP 0.092 PhBP

0.15 PhBP | PBP_GOBP | 0.002

PhBP DUF1789 0.022 PhBP PBP_GOBP |

6E-004 PhBP 6e-004| DUF1789 0.075| COG3271 0.095| 8E-006 Predicted double-glycine peptidase

PBP_GOBP 0.044 0.044| PhBP

Intracellular trafficking, secretion, and vesicular transport PBP_GOBPPBP_GOBP |0.012 PhBP 0.002

Odorant-binding proteinPBP_GOBP 2E-006 PBP_GOBPPBP_GOBP 6E-007 PhBP

4E-09 99a - Drosophila melanogaster - odorant binding - 1e-005| perception of chemical stimulus - olfactory behavior - respo

Posttranslational modification, protein turnover, chaperones 2e-006| PhBP sensory 2E-007

ribosomal structure and 99a - Drosophila melanogaster - odorant binding - 7e-009| Red1

4E-16 biogenesis 4e-012| PhBP sensory perception of chemicalSerine proteases of the peptidase fa

Translation,Odorant-binding proteinPBP_GOBP 4E-012 PBP_GOBPPBP_GOBP 1E-012 PhBP | 1E-010 stimulus - olfactory behavior - respo



General function prediction only Herpes_DNAp_acc 0.016 Herpes_DNAp_acc

CobT Nucleosome binding factor Herpes_

Herpes_DNAp_acc 0.016|0.004 0.027| PRK08581 0.052| Herpes_BLLF1 | COG5406 |SPN, SP

General function prediction only CobT 0.003 CobT 8E-004 Nucleosome binding factor SPN, SP

CobT 0.003| PRK08581 0.005| Herpes_DNAp_acc 0.018| PRK07406 0.027| COG5406 | PRK12

General function prediction only Herpes_DNAp_acc 0.007 Herpes_DNAp_acc

CobT CobT, Cobalamin biosynthesis COG

Herpes_DNAp_acc 0.007|0.002 0.035| PRK08581 0.044| PRK12372 | PRK07406 | CobT |prote

DUF705

Signal transduction mechanisms, Cytoskeleton 0.18 DUF705

DUF705 | COG4016 | 0.052 Uncharacterized protein conserved i

COG4016

Signal transduction mechanisms, Cytoskeleton 0.85 COG4016 | DUF705 0.33 Uncharacterized protein conserved i

COG4016

Signal transduction mechanisms, Cytoskeleton 0.57 COG4016 | UPF0254 | 0.24 Uncharacterized protein conserved i

MDN1

Translation, ribosomal structure and biogenesis 7E-005 Daxx 7E-004 | COG5137 | CDC27 |

MDN1 7e-005| Daxx 0.002| CobT 0.100| CobT | PRK12678MDN1, AAA ATPase containing von

Function unknown MDN1 4E-004 Daxx 8E-004 CobT AAA CobT 0.028| Paf1 von

MDN1 4e-004| Daxx 0.003| VID27 0.005| COG5406 0.017|MDN1,0.018|ATPase containing 0.09



COG3889 5E-005 COG3889 5e-005| PRK11907 | Herpes_gp2 |

Inorganic ion transport and metabolism, Signal transduction mechanisms Herpes_gp2 0.22 Predicted solute binding protein

COG3889 3E-005 COG3889 3e-005| Herpes_gp2 Predicted | Presenilin |

Cell cycle control, cell division, chromosome partitioning, Transcription Herpes_gp2 0.025 0.080| PRK11907 | AstB | PRK06872solute binding protein

virus-induced RNA 1 - Drosophila melanogaster - defense0.072| CobT |virus

Function unknown 6E-09 COG2194 CobT 0.072

0.072 COG2194 response to TFIIF_alpha | CobT | Cwf_Cwc_15 | Predicted membrane-associated, me

Uncharacterized paraquat-inducible





Larval visceral protein H - Drosophila 9E-076 PRK10933 9e-076| Alpha-amylase Aamy metabolic process

0 PRK10933 melanogaster - alpha-glucosidase activity - glucose AmyA 1e-067| Aamy 4e-040| PRK10785 9e-021| G

Carbohydrate transport and metabolism 2

Alpha-amylaseE-069 6e-069| 3E-042 AmyA, Glycosidases

Larval visceral4E-60 H - Drosophila 1E-011 PRK10933 1e-011| AmyA23e-007|glucose metabolic process | Glycosidases

protein PRK10933 melanogaster - alpha-glucosidase activity - Alpha-amylase 7e-006| RecC

Carbohydrate transport and metabolism Alpha-amylaseE-006 AmyA,

Amylase proximal - Drosophila

1E-46 Aamy_C 8E-023 Aamy_C 8e-023| Alpha-amylase_C 2e-010|

Alpha-amylase_C

5E-011 binding

Carbohydrate transport and metabolism melanogaster - alpha-amylase activity - calcium ionAamy_C 1E-024 NrdD, Oxygen-sensitive ribonucleos

Amy35, Amy1:7E-90 Alpha-amylaseE-036 Alpha-amylase 9e-036| AmyA 3e-009| Aamy calcium ion binding -Glycosidases metabolic proc

Alpha-amylase 9 Alpha-amylaseE-036 Aamy

3 3E-007 AmyA, carbohydrate

Carbohydrate transport and metabolism 1 precursor - Drosophila ananassae - alpha-amylase activity -2e-005| PRK09441 0.005| PulA 0.026| PRK12797

Amy35, Amy1:1E-76 Alpha-amylaseE-032 Alpha-amylase 9e-032| Aamy 2e-019| AmyA calcium ion AmyA, carbohydrate metabolic proc

Alpha-amylase 9 Alpha-amylaseE-032 Aamy

2 2E-021 3e-004| PulA 0.003|

Carbohydrate transport and metabolism 1 precursor - Drosophila ananassae - alpha-amylase activity -2e-011| GlgBbinding -GlycosidasesPRK09441 0.00



NUC Endonuclease_NS

4E-016 NUC 1E-007 NUC1, DNA/RNA endonuclease G,

1E-018 NUC 1e-018| Endonuclease_NS 1e-015| NUC1 7e-006| NUC 1e-005|



Alkaline phosphatase 4 alkPPc

2E-30 - Drosophila melanogaster - alkaline phosphatase activity1e-014| alkPPc6E-020 PhoA 2e-004| phosphatase

Inorganic ion transport and metabolism Alk_phosphatase

4E-015 epithelial transport - nervous system development - an

4E-018 alkPPc 4e-018| Alk_phosphatase -alkPPc fluid3e-010| PhoA, Alkaline



HTRA2, OMI, PRSS25: PDZ_serine_protHTRA2,

1E-20 Serine protease 8E-013 PDZ_serine_protease 8e-013| DegQ 1e-008| PDZ_metalloprotease 2e-008| PDZunfolded prote

PDZ - Homo PDZ 3E-009 DegQ, Trypsin-like - 2e-007| PDZ_

Posttranslational modification, protein turnover, chaperones mitochondrial precursor7E-006 sapiens - serine-type endopeptidase activityserine proteases

transport Drosophila melanogaster - 5E-050 Tryp_SPc 5e-050|activity 6E-035 Tryp_SPc 2e-034| COG5640 1e-015| COG3591 0.098| DUF

1E-97 Tryp_SPc

Amino acid CG5390 -and metabolism Trypsin

serine-type endopeptidase Tryp_SPc 8e-048| Trypsin 9E-050 Secreted trypsin-like serine protease

transport Drosophila melanogaster - 4E-009 Tryp_SPc 4e-009|activity 4E-007 Tryp_SPc 4E-011

2E-11 Tryp_SPc

Amino acid CG9673 -and metabolism Trypsin

serine-type endopeptidase Trypsin 1e-006|

transport Drosophila melanogaster - 2E-010 Tryp_SPc 2e-010| Tryp_SPc 2e-010| Trypsin 2e-005| COG5640 0.002|

7E-12 Tryp_SPc

Amino acid CG9631 -and metabolism proteolysis Trypsin 7E-006 Tryp_SPc 4E-012 Secreted trypsin-like serine protease

transport and metabolism

8E-15 family - Colwellia psychrerythraea 34H - Tryp_SPc

Trypsin 3E-014 Tryp_SPc 7E-020 Secreted trypsin-like serine protease

Amino acid serine protease, trypsinTryp_SPc 4E-020 Tryp_SPc 4e-020|proteolysis 5e-018| Trypsin 9e-014| COG5640 3e-009|

transport Drosophila melanogaster - 2E-029 Tryp_SPc 2e-029| Tryp_SPc 5e-027| Trypsin 6e-019| COG5640 1e-008|

4E-26 Tryp_SPc

Amino acid CG4386 -and metabolism proteolysis Trypsin 2E-019 Tryp_SPc 8E-029 Secreted trypsin-like serine protease



Drosophila melanogaster - lysozyme activity Lys

Lysozyme P - 1E-25 LYZ1 - LYZ1 1e-033| Lys 2e-029|

5E-030 response

6E-038 LYZ1 6e-038|antimicrobial humoral LYZ1 2E-035

2E-11 CLECT_collectin binding

sugar Lectin_C 3E-011 CLECT 7E-008

CG9134 - Drosophila melanogaster - 4E-011 CLECT_collectin_like 4e-011| Lectin_C 1e-010| CLECT 8e-008| CLECT_DC-SIGN_like 3e-007

4E-29 protein 1 precursor GH16_beta_GRP 9e-085| of innate

9E-085 Glyco_hydro_16

GH16_laminarinase 1e-032| bacterial binding - extracellular region

SKN1, Beta-glucanase/Beta-glucan

Beta-1,3-glucan-bindingGH16_beta_GRP - Manduca sexta - regulation7E-010 immune response - Glyco_hydrolase_16 3e-019| SKN1 6e-









CG32679 1E-23 SCP_euk - extracellular region SCP 2E-019 SCP 8E-020

Function unknown - Drosophila melanogaster 2E-023 SCP_euk 2e-023| SCP 5e-019| SCP 6e-018| SCP_CRISP 2e-009| SCP_GLIPR-1_like 2e-009|

CG32679 3E-24 SCP_euk - extracellular region SCP 8E-010 SCP 6E-012

Function unknown - Drosophila melanogaster 1E-014 SCP_euk 1e-014| SCP 4e-010| SCP 3e-009| SCP_GAPR-1_like 8e-005| SCP_PR-1_like 3e-00





CG30197 - Drosophila melanogaster - 0.29 PRK10524 |

3E-24 PRK10524 biological_process

Posttranslational modification, protein turnover, chaperones

CG30197 - 4E-24 PRK10524 biological_process

Extracellular structures Drosophila melanogaster - 0.30 PRK10524 |





General function prediction only COG5222 0.14 TRAP_240kDa |

COG5222 | TRAP_240kDa0.19 Uncharacterized conserved protein,





COG5291 0.30 COG5291 | Filo_glycop | 0.13 Predicted membrane protein



Cucumo_coat 0.097 Cucumo_coat 0.027

Intracellular trafficking, secretion, and vesicular transport Cucumo_coat 0.097|





General function prediction only nrdG 0.27 nrdG |

PRK09362 0.27 PRK09362 | PurC, Phosphoribosylaminoimidazol

RHD3 0.26 RHD3

RHD3 | eutD | 0.074 BHL 0.41

RHD3 0.21 RHD3 | RHD3 0.058

RHD3 0.32 RHD3 | RHD3 0.090 Myosin heavy chain

RHD3 0.17 RHD3 | RHD3 0.049 Myosin heavy chain









CRM1, Importin beta-related nuclear









Energy production and conversion DgoK 0.13 Ceramidase_alk.38

DgoK | PRK04542 | 0 DgoK, 2-keto-3-deoxy-galactonokina

Energy production and conversion PRK04542 0.16 PRK04542 |PTSIIA_gutA 0.10 SrlB, Phosphotransferase system so

PRK12904 0.42 PRK12904 | Predicted acetyltransferase

GltP 0.47 Ppx-GppA 0.14 TOPEUc

GltP | Ppx-GppA | Ricin_B_lectin | beta_tubulin | 0.20 GltP, Na+/H+-dicarboxylate symport



Function unknown SMP2 0.52 SMP2 | MAM 0.20 SMP2, Uncharacterized protein invo

CDtoxinA 0.17 CDtoxinA | CDtoxinA 0.049 CENPB 0.53

HOLI 0.23 SMP2, Uncharacterized protein invo



CodB 0.18 CodB | HormR 0.059 CodB, Purine-cytosine permease an

HormR 0.15 CodB, Purine-cytosine permease an

CodB 0.18 CodB | SPC22 0.98 HormR 0.061 CodB, Purine-cytosine permease an

SPC22 0.39 SPC22 | SPC22 0.12 BioF, 7-keto-8-aminopelargonate sy

SPC22 0.88 Predicted SAM-dependent methyltra

MIR 0.51

SPC22 0.90 LCCL 0.88

CodB 0.11 CodB | PRK05937 | CodB, Purine-cytosine permease an

Intracellular trafficking, secretion, and vesicular transport Noc2 0.33 ChaC, Uncharacterized protein invol

Transcription COG3513 0.93 COG3513 | YycH 0.76 START 0.98 Uncharacterized protein conserved i

CodB 0.10 CodB | PRK05937 | HormR 0.71 CodB, Purine-cytosine permease an



0.66

Nitrogenase_Vnf Baculo_VP91_N

Nitrogenase_VnfE_like | 0.42 ChtBD2 0.36

Replication, recombination and repair Clp1 0.57



PRK05325 0.013 PRK05325 0.013| PRK12678 0.014| Sporozoite_P67 0.015| Herpes_LMP2 | GAL11 | PRK1059

Sporozoite_P67

Replication, recombination and repair, RNA processing and modification 0.005 PRP 0.19 CobT, Cobalamin biosynthesis prote

Sporozoite_P670.003 Sporozoite_P67 Sporozoite_P67

9E-004 PRP 0.60

Replication, recombination and repair, RNA processing and modification 0.003| Herpes_LMP2 0.063| PRK05325 0.098| PRK12678 | secA | Totivirus_co

Sporozoite_P670.001 Sporozoite_P67 Sporozoite_P67

3E-004 PRP 0.83

Replication, recombination and repair, RNA processing and modification 0.001| PRK12678 0.007| Herpes_LMP2 0.062| PRK05325 | secA | PRK10590





Cytoskeleton 0 Actin structural constituent Actin

of cytoskeleton - ACTIN 2e-093| COG5277 3e-061| and related proteins

2E-095 ACTIN 7E-097 Actin

Actin 5C - Drosophila melanogaster - 5E-095 Actin 5e-095| ACTIN 6e-095| actin filament - cytoskeleton organization and biogenesis - sperm

Cytoskeleton 0 ACTIN structural constituent Actin

of cytoskeleton - actin filament - cytoskeleton organization| and biogenesis

1E-136 ACTIN 1E-138 Actin and PRK06940 |

Actin 5C - Drosophila melanogaster - 1E-136 ACTIN e-136| Actin e-135| ACTIN e-135| COG5277 2e-090| DUF248related proteins - sperm

ribosomal structure and biogenesis 3E-012 RplW 3e-012| cytosol - translational elongation 0.39 RplW, Ribosomal protein L23

7E-46 - Rattus Ribosomal_L23 4E-009 COLFI

Translation,ribosomal protein L23a RplW norvegicus - protein binding - rplW 1e-010| Ribosomal_L23 1e-008| PRK09138 0.003| PRK08173 0.014| TEBP

Cytoskeleton rne SSL1 |

7E-004 rne 7e-004| CDC45 PRK12678 | 0.98 Small-conductance mechanosensitiv

Cytoplasmic linker prediction - Drosophila melanogaster 4e-023| NIP100 5e-016| STI | COG4717 |

1E-73 CAP_GLY microtubule 1E-023 PsiA 0.63 NIP100, actin binding - protein bind

Cytoskeleton, General functionprotein 190only 4E-023 CAP_GLY -CAP_GLY binding - microtubule associated complex - Dynactin complex subunit in

9E-52 Drosophila melanogaster - microtubule associated complex - microtubule-based movement - ATPase activity, coupled

Cell motility Dynein light chain 90F -Tctex-1 2E-036 Tctex-1 2e-036| Tctex-1 5E-037



Signal transduction mechanisms RAP1 RAP1 4E-005 CobN, Cobalamin PRK08691 PRK

1E-004 RAP1 1e-004| CobN 5e-004| PRK07003 0.013| Herpes_BLLF1 | PRK07764 | biosynthesis| prote

Cytoskeleton Herpes_BLLF1 0.009 CobN, 0.034| PRK12373 0.044| PRK

PRK07003 0.005 PRK07003 0.005| CobN 0.009| PRK12323 0.025| Herpes_BLLF1 Cobalamin biosynthesis prote

carbohydrate (chondroitin 4) sulfotransferase 13 - Rattus Sulfotransfer_2 | COG3893 | PRK07847 | entE | Mg2+ and chondroitin sulfate

0.000005 Sulfotransfer_22E-010 Sulfotransfer_2 2e-010| CorA5E-011 CorA,

Cell wall/membrane/envelope biogenesis, Extracellular structures norvegicus - N-acetylgalactosamine 4-O-sulfotransferase activity -Co2+ transporters

Matrix metalloproteinase - Drosophila melanogaster - metalloendopeptidase activity

7E-17 HX 7E-015 HX 7e-015| Hemopexin Hemopexin 5e-007| PRK09039 |

HX 2e-007| 3E-009

Posttranslational modification, protein1turnover, chaperones, Extracellular structures 2E-007 HX - open tracheal system development - dorsal trunk grow

1E-12 melanogaster -0.42 guidance - synaptic target recognition - axonal fasciculation -TFA2, Transcription initiation factor I

Fasciclin 3 - DrosophilaTFA2 axon TFA2 | I-set 0.43 OSTEO 0.56 homophilic cell adhesion - synaptic

trafficking, Drosophila Annexin

7E-45 melanogaster4E-015

- calcium-dependent Annexin

phospholipid binding ANX

1E-015 6E-013

Intracellular Annexin X -secretion, and vesicular transport Annexin 4e-015| ANX 4e-011| - calcium ion binding - phospholipid binding - actin binding



4E-09 PRK11760 0.77 PRK11760

spatzle - Drosophila melanogaster - Toll signaling pathway|- maternal determination of dorsal/ventral axis, oocyte, germ-line encoded - oocyte



transport and metabolism

9E-14 Abhydrolase_3E-005 cellular_component

8 Abhydrolase_3E-005

3

Amino acid zgc:112472 - Danio rerio - biological_process - Abhydrolase_3 8e-005| Aes 0.001| DAP2 | DLH | Aes, Esterase/lipase

transport and metabolism, Posttranslational modification, protein turnover,0.41 PB1

4E-25 PepN 0.21 PepN | POPLD chaperones 0.93 PepN, membrane - integral

Amino acid ENPEP: Glutamyl aminopeptidase - Homo sapiens - cell-cell signaling - cell proliferation - cell migration - plasma Aminopeptidase N to plasm

RNA 4E-45 RNA_pol_Rpb6 1E-011 RNA_pol_Rpb6 1e-011| rpoK 3e-011| RpoZ 2e-008| rpoK 3e-008|DNA-directed RNA polymeras

RNA_pol_Rpb6 3E-012 OSTEO 0.46 RpoZ, rpoK 4e-008| COG5406 CO

Transcription polymerase II 18kD subunit - Drosophila melanogaster - DNA-directed RNA polymerase activity - transcription from RNA polymerase|II pr

zgc:103699 - Danio rerio - biological_process SrfB |

Function unknown 0.001 SrfB 0.54 TR_FER 0.10 SrfB, Uncharacterized protein conse

Function unknown COG3333 0.29 COG3333 | Uncharacterized protein conserved i

transport and metabolism

2E-41 PRK08201 3E-008 PRK08201 3e-008| PRK09104 dipeptidase activity 5e-006| Peptidase_M20 5e-004| ArgE 0.004

Peptidase_M20 1E-004 HTTM - proteolysis

Amino acid CNDP dipeptidase 2 (metallopeptidase M20 family) - Mus musculus - cytosol - 1e-007| PRK079070.60 ArgE, Acetylornithine deacetylase/S

transport Drosophila melanogaster - 6E-028 PRK07334 6e-028| PRK08198 3e-024| PRK08526 3e-019|IlvA, 6e-016| PRK06382 2e-013| AC

5E-49 PRK07334 L-threonine ammonia-lyase activity 0.028

Amino acid CG8129 -and metabolism ACT IlvA Threonine dehydratase

transport Drosophila melanogaster - 5E-067 GcvT 5e-067| gcvT 3e-065| GCV_T 4e-054| dmdA -3e-017| GcvT, Glycine cleavage system T pr

3E-94 GcvT

Amino acid CG6415 -and metabolism GCV_T 1E-054 catabolic process lipid particle

aminomethyltransferase activity - glycine cleavage complex glycine GCV_T_C 2e-014|- COG0354 8e-00

4E-10

SRY interacting protein 1 - Drosophila melanogaster - olfactory behavior



CG33138 - and metabolism

0 GlgB - 1,4-alpha-glucan branching enzyme activityAamy

Alpha-amylase0.41 0.38 GlgB, 1,4-alpha-glucan branching en

Carbohydrate transport Drosophila melanogaster 7E-039 GlgB 7e-039| PRK12313 2e-025| PRK05402 4e-025| PRK12568 9e-015| PulA 0.021| PRK0370

hydroxypyruvate isomerase,

4E-45 Hfi - Pseudomonas syringae pv. phaseolicola - hydroxypyruvate isomerase activity - carboxylic acid metabol

AP_endonuc_22E-018 Hfi, Hydroxypyruvate isomerase

Carbohydrate transport and metabolism putative 3E-062 Hfi 3e-062| PRK09997 1e-045| PRK09989 2e-043| AP_endonuc_2 8e-018| IolE 2e-014| COG4

GALK1, GALK: metabolism

7E-67 GalK 2E-065 - galactokinase activity - 3E-012 PRK05101 1e-057| PRK03817 5e-048| PRK00555 3e-040| G

GHMP_kinases_C

2e-062| GalK, Galactokinase

Carbohydrate transport andGalactokinase - Homo sapiens GalK 2e-065| PRK05322ATP binding - galactose binding - galactose metabolic process - memb

PGLS: 6-phosphogluconolactonase - 4E-047sapiens - 4e-047| NagB 1e-030| GlcN6P_deaminase 0.085 nagB 2e-007| PRK12358 4e-007| PR

6E-43 6PGL

Carbohydrate transport and metabolism Glucosamine_iso

shunt

Homo 6PGL pentose-phosphate 0.51 AAA 4e-011| NagB, 6-phosphogluconolactonase/G

CG10178 - and metabolism, Energy 9E-015 UDPGT 9e-015|

4E-77 UDPGT - glucuronosyltransferase

UDPGT

Carbohydrate transport Drosophila melanogaster production and conversionactivity 2E-015 JHBP 0.14

UGP - Drosophila melanogaster - UTP:glucose-1-phosphate uridylyltransferase activity

2E-81 UDPGP

Carbohydrate transport and metabolism UDPGP 7E-040

2E-039 UDPGP 2e-039| COG4284 7e-016|ZU5 0.30 UDP-glucose pyrophosphorylase

Glyceraldehyde metabolism

7E-42 GapA 2E-033 - Drosophila melanogaster - glycolysis - glyceraldehyde-3-phosphate dehydrogenase (phospho

Gp_dh_C 4E-029 AP2Ec 0.23 GapA, Glyceraldehyde-3-phosphate

Carbohydrate transport and 3 phosphate dehydrogenase 2 GapA 2e-033| Gp_dh_C 2e-028| PRK07729 8e-024| PRK07403 1e-022| PRK08955 2e-019| PR

importin 13 - Rattus norvegicus - protein binding - NLS-dependent | DUF1635 HECTc

6E-19 Mal 0.13 Mal | MAL | MAAL_C nuclear

Nuclear structure, Intracellular trafficking, secretion, and vesicular transport protein 0.11 | import complex0.29 Mal, Methylaspartate ammonia-lyase



CG7998 - conversion MDH_glycosomal_

2E-95 L-malate MDH_glycosomal_mitochondrial e-102| PRK050860.70

Ldh_1_C 1E-041 SET 1e-081| LDH_MDH- 6e-048| Mdh 8e-045| Ld

acid cycle lipid particle

Energy production andDrosophila melanogaster - 1E-102 dehydrogenase activity - mitochondrial matrix - tricarboxylicMdh, Malate/lactate dehydrogenase

lethal and conversion

- Drosophila melanogaster - mitochondrial electron transport, NADH to ubiquinone - NADH dehydrogenase activity - mitochondr

Energy production(2) 35Di 5E-34 BisC, Anaerobic dehydrogenases, ty

hydroxyacyl-CoenzymeFadB

Lipid transport and metabolism 3E-079 FadB 3e-079|3-hydroxyacyl-CoA PRK07819 2e-064| PRK09117 4e-063| mitochondrial inner P

- PRK08268 2e-067| RIO 0.12 FadB, 3-hydroxyacyl-CoA 5e-060| m

3E-93 A dehydrogenase - Mus musculus 3HCDH_N 3E-046 dehydrogenase activity - mitochondrion -PRK05808 dehydroge

ATP synthase-beta - Drosophila melanogaster PRK09280 2e-055| AtpD 1E-021 atpB 2e-044| PRK12597 1e-037| ATP-synt_ab_C 4e-021| beta

2E-58 ATP-synt_ab_C3e-051| AtpD, F0F1-type ATP synthase, PR

Energy production and conversion PRK09280 2E-055 - hydrogen-exporting ATPase activity, phosphorylative mechanism - proton transport - mitochon

ATP synthase-beta - Drosophila melanogaster PRK09280 e-163| AtpD e-154| F1-ATPase_beta e-138| atpB e-136| proton transport - ATP-syn

0 ATP-synt_ab 2E-061 AAA 5E-005 AtpD, F0F1-type ATP synthase, beta

Energy production and conversion PRK09280 1E-163 - hydrogen-exporting ATPase activity, phosphorylative mechanism - PRK12597 e-121| mitochon

ubiquinol cytochrome reductase core

9E-39 4E-016 Peptidase_M16 4e-016| PqqL binding COG3437 | 0.37 PqqL, Predicted membrane

Peptidase_M161E-016 REC

Energy production and conversionc Peptidase_M16 protein 2 - Rattus norvegicus - protein 2e-013| - mitochondrion - mitochondrial inner Zn-dependent pepti

ATP synthase,1E-62 Mt_ATP-synt_B

subunit melanogaster - hydrogen-exporting ATPase activity,

Mt_ATP-synt_B 0.25 mechanism - proton DNA-directed

Energy production and conversion b - Drosophila7E-038 Mt_ATP-synt_B 7e-038| 2E-038 RasGEFphosphorylativeRPO41, Mitochondrialtransport - mito

Malic enzyme 1E-22

- Drosophila melanogaster - malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity enzyme

Energy production and conversion Malic_M Malic_M

3E-009 Malic_M 3e-009| SfcA 0.002| 9E-010 SfcA, Malic

Malic enzyme - Drosophila melanogaster - malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity enzyme

0

Energy production and conversion Malic_M Malic_M 5E-079 SfcA, PRK12862 3e-023| PRK12861

2E-078 Malic_M 2e-078| SfcA 1e-060| malic 6e-044| PRK07232 3e-023| Malic

CG4692 - conversion PRK11459

3E-47 0.29 PRK11459 |PUCC activity,0.76

Ndh |

Energy production andDrosophila melanogaster - hydrogen-exporting ATPase PRK07860 | Ndh, transport - mitochondrial proto

phosphorylative mechanism - proton NADH dehydrogenase, FAD-co

NDUFB2: NADH dehydrogenase [ubiquinone] 1

1E-13 Glyco_32 0.15

Posttranslational modification, protein turnover, chaperones beta subcomplex subunit 2, mitochondrial precursor - Homo sapiens - NADH dehydrogenase

ATP synthase,3E-51 Mt_ATP-synt_B

subunit melanogaster - hydrogen-exporting ATPase activity,

Mt_ATP-synt_B 0.20 mechanism - proton DNA-directed

Energy production and conversion b - Drosophila1E-030 Mt_ATP-synt_B 1e-030| 4E-031 RasGEFphosphorylativeRPO41, Mitochondrialtransport - mito

Transcription homolog, subfamily C, member 2 - Mus0.001| SANTprotein 0.002 -SANT replication -RSC8RSC8, RSC |chromatin remodeling c

DnaJ (Hsp40) 2E-16 SANT Myb_DNA-bindingMyb_DNA-binding 0.007| G2 phase of TEA cell cycle

0.001 SANT musculus - 0.004| binding DNA 4E-005 0.037| mitotic

ATP synthase-gamma ATP-synt

1E-94 1E-048 ATP-synt hydrogen-exporting ATPase activity, phosphorylative F0F1-type ATP synthase, gam

ATP-synt 3E-049 ArfGap 0.51 AtpG,

Energy production and conversion chain - Drosophila melanogaster -1e-048| PRK05621 1e-038| AtpG 2e-038| PRK00955 |mechanism - proton transport -

trafficking, NADH dehydrogenase transport 1 alpha subcomplex

0.0001 Tim17 0.17 Tim17 0.050

Intracellular NDUFA11: secretion, and vesicular[ubiquinone]Tim17 | PRK09841 | subunit 11 - Bos taurus - mitochondrion

ribosomal structure rps5p

Drosophila melanogaster - rps5p 2e-061| RpsE 2e-041| Ribosomal_S5 cytosolic smallRpsE, Ribosomal_S5_C S5 - lipid

Ribosomal_S5 E-021 TR_THY

1 0.038 ribosomal subunit - ribosome

Translation,string of pearls - 0 and biogenesis 2E-061translation - structural constituent of ribosome - 4e-021| rpsE 7e-018| Ribosomal protein 2e-017| rps

ribosomal protein S6 - PRK05035 melanogaster - translation - structural constituent PRK00247 infB

2E-37 Drosophila MMS22 0.053 TOP2c cytosolic small | PRK12373 | PRK00409 |

TolA, Membrane subunit - ribosome

Translation,Ribosomal structure and biogenesis 1E-005 PRK05035 1e-005| TolA 0.015| tolA | of ribosome| -0.19 | PRK11778ribosomalprotein involved ind

Hexokinase A 9E-76 Hexokinase_2

- metabolism 1E-040 Hexokinase_2 Hexokinase_2 3E-041 IL7

Carbohydrate transport andDrosophila melanogaster - hexokinase activity1e-040| COG5026 1e-021| 0.95 Hexokinase

ubiquinol cytochrome reductase core protein 2 - Mus musculus - 6e-010| PqqL | - mitochondrial inner membrane

4E-17

Energy production and conversionc Peptidase_M16_C Peptidase_M16_C

6E-010 Peptidase_M16_C mitochondrion2E-010 PqqL, Predicted Zn-dependent pepti

AAEL002956: 1E-79 citrate synthase 1, mitochondrial precursor - Aedes aegypti - citrate 6e-030| gltA activity mitochondrial matrix - carbo

Probable Citrate_synt 3E-043 INB 0.49 GltA, Citrate synthase

Energy production and conversion PRK09569 8E-056 PRK09569 8e-056| Citrate_synt 1e-042| GltA(Si)-synthase 1e-008| -PRK12351 6e-008| PRK123

ATP citrate lyase0- Drosophila 9E-032 SucD 9e-032| Ligase_CoA 5e-023| PIPKc

Ligase_CoA 1E-023 PRK05678 5e-018| GltA ATP Succinyl-CoA synthetase, alp

0.29 - 5e-013| PRK06224 3e-010|

Energy production and conversion SucD melanogaster - acetyl-CoA biosynthetic process - citrate metabolic process SucD, citrate synthase activity - cyto





yippee metabolism 0 thiolase 1E-108 thiolase acetyl-CoA C-acyltransferase activity - mitochondrion - Acetyl-CoA acetyltransferase

Thiolase_N 9E-048 PTX 0.27 PaaJ, 9e-078| beta-oxidation - lipid

Lipid transport and interacting protein 2 - Drosophila melanogaster -e-108| PRK06845 e-102| PRK09051 6e-087| PRK05790fatty acid PRK09050 8e-075| P

thioredoxin peroxidase 2 Drosophila1E-054 PRX_Typ2cys 1e-054| AhpC 7e-048| PRX_1cys 2e-026| PRX_family 5e-021| PRK10382 3e-01

3E-63 PRX_Typ2cys melanogaster - antioxidant activity 7E-016 35EXOc

Posttranslational modification, protein- turnover, chaperones activity peroxidase activity -

AhpC-TSA - thioredoxin peroxidase 1.00 -AhpC, Peroxiredoxin extracellular re

CG2145 - Drosophila XendoU

3E-90 serine-type peptidaseXendoU

activity

General function prediction only melanogaster - 5E-036 XendoU 5e-036| DUF5061E-036 | LeuS, Leucyl-tRNA synthetase



Thiolase - Drosophila thiolase

0 acetyl-CoA C-acyltransferase 7e-068| fatty acid beta-oxidation - long-chain-3-hydroxyacyl-CoA dehydrog

Thiolase_C 5E-037 PaaJ, Acetyl-CoA acetyltransferase

Lipid transport and metabolism melanogaster - 3E-071 thiolase 3e-071| fadI activity - PRK08170 4e-056| PRK09268 2e-055| PRK06445 5e-045| PRK06

CG3523 - Drosophila COG3319 fatty-acid synthase 5e-021| Thioesterase

2E-63 Thioesterase 6E-018 Thioesterase domains of type I polyk

Lipid transport and metabolism melanogaster - 5E-021 COG3319activity - lipid particle 2e-017| PRK10252 4e-007| GrsT 1e-005| PRK12467 0.009|

CG8199 - conversion TPP_E1_PDC_ADC_

0 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity - 3-methyl-2-oxobutan

E1_dh 6E-054 Glyco_10 0.60 2e-053| TPP_TK 6e-011| TPP_enz

Energy production andDrosophila melanogaster - 3E-068 TPP_E1_PDC_ADC_BCADC 3e-068| AcoA 9e-067| E1_dhAcoA, Pyruvate/2-oxoglutarate dehy

bubblegum - DrosophilaFAA1

2E-53

Lipid transport and metabolism 2E-012 FAA1 2e-012| PRK08180 0.001| - long-chain fatty 0.71 metabolic process - cellular_componen

H15 acid

melanogaster - long-chain-fatty-acid-CoA ligase activity PRK12582 | PRK00950 | FAA1, Long-chain acyl-CoA syntheta

PSAP, metabolism, Proactivator transport and metabolism SAPA 0.001| SapA 0.001| SapB_2 enzyme activator activity - lipid

SAP1: SapB 3E-007 SapB 3e-007| SapA 4E-004 SapB 0.009|

Lipid transport and GLBA, 1E-19 Carbohydratepolypeptide precursor [Contains: Saposin-A - Homo sapiens - 4E-009 ACC_central | SapB_1 | binding - glyco

CG5508 - Drosophila VP7

1E-20 0.43 VP7 | B-block_TFIIIC |

Lipid transport and metabolism melanogaster - glycerol-3-phosphate VP7 0.14

O-acyltransferase activity - phospholipid biosynthetic process - plasma membrane



ade5 - Drosophila melanogaster - phosphoribosylaminoimidazole carboxylase activity - phosphoribosylaminoimidazolesuccinocarboxamide syn

0

Nucleotide transport and metabolism 5E-042 SAICAR_synt_Ade5 5e-042| AIRC 4e-036| SAICAR_synt 1e-023|Phosphoribosylcarboxyaminoi

SAICAR_synt_Ade AIRC 1E-036 CLa 0.17 PurE, SAICAR_synt 5e-022| PurE 2

CG2145 - Drosophila XendoU

3E-90 serine-type peptidaseXendoU

activity

General function prediction only melanogaster - 5E-036 XendoU 5e-036| DUF5061E-036| LeuS, Leucyl-tRNA synthetase

transport and metabolism

1E-08 DLH 0.23 cellular_component

DLH

Amino acid zgc:112472 - Danio rerio - biological_process - DLH | Abhydrolase_3 | 0.073 3-oxoacyl



histone and dynamics Rattus norvegicus - DNA binding Histone

1, H4b

Chromatin structurecluster2E-48 - H4 4E-009 H4 1E-029 0.022| TAF6 0.049| CBFD_NFYB_H

4E-030 H4 4e-030| H4 7e-028| HHT1 9e-019| Histone 1e-008| TAFHHT1, Histones H3 and H4

ribosomal protein S10b Drosophila melanogaster - structural constituent of ribosome DmpA | DmpA | PRK12678 subunit S10E

6E-42 S10_plectin 3e-027| COG5045 1e-015| - cytosolic small ribosomal | PRK11634 |

Translation,Ribosomal structure and -biogenesis 3E-027 S10_plectinS10_plectin 9E-028 Ribosomal protein

CIAPIN1, 5E-30 DUF689 1E-036 DUF689 1e-036| COG5636 cytoplasm

DUF689

Function unknown CUA001, PRO0915: Anamorsin - Homo sapiens - anti-apoptosis -3e-017| 5E-037 Uncharacterized conserved protein,

MOB1, Mps One BinderMob1_phoceinE-064 Mob1_phocein 5e-064| 1E-064

6E-80 kinase activator-like

5 Mob1_phocein

Cell cycle control, cell division, chromosome partitioning 2B (yeast) - Rattus norvegicus - protein binding Uncharacterized protein conserved i



trafficking, secretion, and vesicular transport clathrin vesicle coat - Uup 0.054| PRK05771 0.057| BMS1 neurotransmitter transportABC tr

1E-36 Clathrin_lg_ch 6E-020 Clathrin_lg_ch

2E-020 TOPEUc 0.059 Uup, ATPase components of PRK

Intracellular Clathrin light chain - Drosophila melanogaster -Clathrin_lg_ch 6e-020|coated pit - neurotransmitter secretion| -Peptidase_C37 | Atrophin-1 -| syna

Rab-protein 7 5E-69 Rab7

- only 2E-059 Rab7 2e-059|endosome to Rab 2e-034| Rab9 - endosome transportRab11_like 4e-025| Ras_lik

- RAB 5E-034 RAB 1E-039 2e-033| - late endosome small G p

General function prediction Drosophila melanogaster - GTPase activity Ras 8e-038| lysosome transport 2e-034| RasGTPase SAR1 and related - autopha

trafficking, secretion, and subunit transport Coatomer_E 2e-076| COG1729 0.006| TPR 0.013| PilF | COG4783 | RPN2 |protein conserved

4E-78 Coatomer_E 2E-076 Coatomer_E 4E-077 TPR 0.021 Uncharacterized - intra-Golgi vesic

Intracellular COPE, COPE1: Coatomervesicularepsilon - Bos taurus - protein binding - retrograde vesicle-mediated transport, Golgi to ERCOG3118 | TPR_i

trafficking, secretion, and subunit transport Coatomer_E 1e-077| TPR retrograde vesicle-mediated transport, Golgi

1E-78 Coatomer_E 1E-077 Coatomer_E 4E-078 TPR 0.029 Uncharacterized protein conserved i

Intracellular COPE, COPE1: Coatomervesicularepsilon - Bos taurus - protein binding - 0.018| COG1729 0.031| COG4783 | PilF | to ER - intra-Golgi vesic

trafficking, secretion, and vesicular transport

6E-45 Adap_comp_sub ommochrome biosynthetic 2e-023| - clathrin ACTIN

Adap_comp_sub | MRS6 |

gltA 0.40 MRS6, Vacuolar protein sorting-asso

Intracellular carmine - Drosophila melanogaster - 2E-023 Adap_comp_sub process 7E-024 adaptor complex - neurotransmitter secretion - synaptic vesi

nuclear RNA export factor 2 - Drosophila melanogaster0.007| AMPD | COG3888 | INBcytoplasm -0.71 Predicted transcriptional regulator

0.0007

RNA processing and modification TAP_C TAP_C 0.002

0.007 TAP_C - mRNA export from nucleus - nucleoplasm

Glutathione S 5E-22 GST_C_Delta_Eps

transferase turnover, chaperones

2E-027 GST_C_Delta_Epsilon 2e-027| GST_C_Ure2p_like 9e-008| GST_C_1 2e-006| GST_C_Theta 5

GST_C 3E-006 HECTc

Posttranslational modification, protein E5 - Drosophila melanogaster - glutathione transferase activity 0.26 Gst, Glutathione S-transferase

trafficking, secretion, and vesicular transport TRAP_alpha 2e-079| ZntA 0.037| PRK08434 | COG1361 | ZntA, TadB particle

8E-92 TRAP_alpha 2E-079 TRAP_alpha 5E-080 complex - lipid

Intracellular lethal (1) G0320 - Drosophila melanogaster - signal sequence binding - signal recognition particle receptorscpA |Cation |transport ATPase



transport and metabolism

2E-51 Tryp_SPc 1E-054 Tryp_SPc -Trypsin dorsal/ventral axis specification maternal determination of DUF316 5e-004| COG

9E-042 Tryp_SPc 7E-055 Secreted trypsin-like serine protease

Amino acid easter - Drosophila melanogaster - Toll signaling pathway1e-054| Tryp_SPc 6e-053| Trypsin- 3e-041| COG5640 9e-025|dorsal/ventral axis, ooc

Heat modification, cognate 3 - Drosophila melanogaster - response to heat - DnaKRIBOc dnaK 0.31 DnaK,0.025| - sleep - RNA interferen

2E-56 HSP70 9E-019 HSP70 9e-019| dnaK 3e-016| ATPase activity - endoplasmic reticulum

Posttranslational shock proteinprotein turnover, chaperones HSP70 3E-019 9e-012| 8e-008| hscA Molecular chaperone

Heat modification, cognate 3 - Drosophila melanogaster - responsee-101| DnaK 2e-075| dnaK endoplasmic reticulumhscA 3e-030| FGGY_C |

0 HSP70 1E-106 HSP70 e-106| dnaK to heat - ATPase activity - 3e-075| hscA 4e-060| - sleep - RNA interferen

Posttranslational shock proteinprotein turnover, chaperones HSP70 1E-106 RIBOc 0.39 DnaK, Molecular chaperone

Nedd4 family interacting protein 1

1E-20 0.090 - cellular_component - biological_process - molecular_function

DUF1097 0.027 LYZ1 0.54

General function prediction only DUF1097 - Danio rerio DUF1097 0.090| CRISPR_Cse1 | PRK10747 | COG1685 | Archaeal shikimate kinase

Cellular Repressor of E1A-stimulated Genes - Drosophila melanogaster - negative regulation of transcription - protein binding - transcription re

Transcription 5E-39 SMP2 0.65 SMP2 | SMP2, Uncharacterized protein invo

zgc:123177 - Danio rerio - biological_process - DUF1649 5e-036| DUF1501 0.099| LIF_OSM | 0.43 Acetyl/propionyl-CoA carboxylase, a

Function unknown DUF1649 2E-036 PRK06111

4E-54 DUF1649 5E-036 molecular_function - cellular_component

Elongation factor 1 betaEF1_GNE 5E-029 EF1_GNE 5e-029| EF1B factor activity - 2e-015| -GST_C_Delta_Epsilon factor elongation factor

Transcription 7E-78 EF1_GNE 5e-028| DM10 0.37 EFB1, Translation ef1B 0.004| Gst

- Drosophila melanogaster - translation release 1E-029 EFB1 cytosol translation elongation 0.004|activity - eukaryo

zgc:110239 - Danio rerio cellular_component Peptidase_C1A 7e-033| Peptidase_C1 2e-030| Pept_C1 5e-022| Peptidase_C1A_CathepsinB 6

2E-44 Peptidase_C1A 7E-033

Posttranslational modification, protein- turnover, chaperones Peptidase_C15E-031 Pept_C1 8E-024 Cysteine protease

2E-64 P5_C 2E-053 P5_C 2e-053| UPF0075 binding

protein disulfide isomerase associated 6 - Rattus norvegicus - calcium ion 0.57 - protein binding - endoplasmic reticulum lumen - ER-Golgi i

CG10635 - Drosophila melanogaster 2E-006 Prefoldin_2 Prefoldin_2 5E-007 PRK10642 0.014| lldD GimC, Prefoldin,

5E-22 Prefoldin_2 - 'de novo' 2e-006| GimC 0.007|

Posttranslational modification, protein turnover, chaperones protein folding - chaperone binding - prefoldin complex 0.055| PRK09343 | chaperonin cofacto

ribosomal structure melanogaster translational initiation eIF2A binding - translation tolB | COG0478 | Uncharacterized protein, translation

4E-81 eIF2A - mRNA 4e-015| WD40 0.67

Translation,eIF3-S9 - Drosophilaand biogenesis- 6E-017 eIF2A 6e-017| COG5354 2E-017 Rgp1 | initiation factor activity - cytosol - eukaryoticcontains Tr

rhomboid-7 - Drosophila melanogaster0.30 PRK01908 |Rhomboid

3E-31

Signal transduction mechanisms PRK01908 - mitochondrial fusionPA_TfR | 0.72

Cyclophilin 1 - 3E-78 cyclophilin_ABH

Drosophila turnover, chaperones

1E-075 cyclophilin_ABH_like 1e-075| Pro_isomerase - protein folding - Peptidyl-prolyl3e-040| cyclophi

Pro_isomerase 2E-068 HALZ 0.40 PpiB, 7e-043| PpiB cis-trans isome

Posttranslational modification, protein melanogaster - peptidyl-prolyl cis-trans isomerase activity - cytosol7e-068| cyclophilincytoplasm - cyclin-dependent p

Golgi microtubule-associated protein Drosophila melanogaster cis-Golgi 0.090| Glyco_18

6E-36 DUF1669 0.025 0.19 | Myosin_tail_1 | COG4717 | Smc H

General function prediction only PRK01156 -0.016 PRK01156 0.016|- DUF1669 networkPRK02224 | COG1579 Zn-ribbon protein, possibly nucleic|a

CG11306 - Drosophila melanogaster 5E-011 RfaG 5e-011| Glycos_transf_1 6e-010|

8E-67 RfaG

Cell wall/membrane/envelope biogenesis Glycos_transf_12E-010

- alpha-1,2-mannosyltransferase activity RfaG, Glycosyltransferase

CG1847 - Drosophila melanogaster - aryl hydrocarbon receptor binding |0.11 TPR

3E-38 PRK08188 0.11 PRK08188 |TPR_2 TPR_2

Posttranslational modification, protein turnover, chaperones TPR | 0.15



Rpt4 modification, protein turnover, chaperones

0 RPT1 1E-134 RPT1 e-134| PRK03992 e-116| SpoVK 7e-064| AAA 7e-057| HflB 2e-055| hflB 8e-050| COG12

AAA 2E-057 AAA - ATPase activity - endopeptidase activity - pr

Posttranslational - Drosophila melanogaster - proteasome regulatory particle, base subcomplex - proteolysis7E-014 RPT1, ATP-dependent 26S proteaso

Pros45 - Drosophila melanogaster endopeptidase 1e-092|proteasome2E-025 SpoVK 1e-032| HflB 2e-028| hflB 6e-025| AAA 6e-025| COG

0 RPT1 1E-092 RPT1 - PRK03992 6e-076| AAA

Posttranslational modification, protein turnover,- chaperones activity AAA 2E-009 RPT1, ATP-dependent 26S proteaso

regulatory particle, base subcomplex - proteasome regulatory particle

ribosomal structure and biogenesis 6E-023 Ubiquitin 6e-023| Ribosomal_S27 UBQ - ubiquitin-dependent protein catabolic process - pro

3E-58 Ubiquitin Ribosomal_S27 response to heat 2E-015 UBQ 1e-013| Nedd8 7e-013| UBL

Translation,Ubiquitin-63E - Drosophila melanogaster - protein modification process - 2E-018 6e-018| ubiquitin 3e-014|RPS31, Ribosomal protein S27AE 2

lethal with a checkpoint HUL4 - Drosophila melanogaster -HECT 8e-034| ligaseHECTc - transforming growth factor beta receptor signaling

6E-54 kinase 2E-034 HUL4 2e-034| HECT

Posttranslational modification, protein turnover, chaperones 3E-034 activity 1E-029 HUL4, Ubiquitin-protein ligase

ubiquitin-protein HECTc 9e-030| HECTc 8e-028|

lethal (2) 05070 - protein turnover, chaperones

8E-32 proteasome_beta 2E-030 proteasome_beta_type_62E-012 core complex 0.40 PRE1, 20S proteasome, alpha and b

Proteasome 2e-030| G_alpha

Posttranslational modification,Drosophila melanogaster - endopeptidase activity - proteasome proteasome_beta 8e-018| Proteasome 8e-012| proteasome_



ribosomal structure and biogenesis aminoacyl-tRNA synthetase auxiliary protein activity - aminoacyl-tRNA synthetase multienzyme complex

3E-75 tRNA_bind_EMAP- tRNA_bind 4e-038| ARC1, EMAP domain

Translation,CG8235 - Drosophila melanogaster - 4E-038 tRNA_bind_EMAP-II_like 6E-022 metG 3e-024| tRNA_bindingDomain 4e-023| tRNA_bind 2e-0

ribosomal structure - Rattus norvegicus - structural 9e-039| rps3p 3e-031| - protein binding - cytoplasm RpsC, Ribosomal protein S3 rpsC

0 RpsC Ribosomal_S3_C 4E-019 KH Ribosomal_S3_C translation - 3e-007|

Translation,ribosomal protein S3and biogenesis 9E-039 RpsCconstituent of ribosome40S_S3_KH 4e-028|0.058 - cytosol -2e-018| rps3 translational e

ribosomal structure and - Drosophila melanogaster - histidyl-tRNA aminoacylationMCM

0 HisS tRNA-synt_2b3E-025 - PRK12420 7e-040| HisS, Histidyl-tRNA synthetase

0.10 activity

Translation,Histidyl-tRNA synthetasebiogenesis 2E-052 HisS 2e-052| HisRS-like_core 3e-048|histidine-tRNA ligasehisS 1e-038| HisZ 1e-024| tRNA-syn

ribosomal protein L35A Drosophila melanogaster - translation - 5e-025| COG2451 1e-019| PRK04337 2e-010|

2E-40 Ribosomal_L35Ae Ribosomal_L35Ae 2E-025 Ribosomal protein L35AE/L33A

Translation,Ribosomal structure and -biogenesis 5E-025 Ribosomal_L35Ae structural constituent of ribosome - cytosolic large ribosomal subunit

ribosomal protein L7 - Drosophila melanogaster - translation structural 5E-012 POLBc

3E-77 Ribosomal_L7 Ribosomal_L30 constituent Ribosomal_L30 cytosolic large ribosomal subunit -L30/L7E

RpmD, Ribosomal protein mRNA bi

Translation,Ribosomal structure and biogenesis 7E-058 Ribosomal_L7-7e-058| rpl30p 4e-022|of ribosome -0.302e-011| Ribosomal_L30_L7 2e-011| Rpm

spt4 3E-36 Spt4 3E-036 Spt4 3e-036| SPT4 6e-023|

Spt4 1E-036

Transcription - Drosophila melanogaster - non-covalent chromatin modification - nucleus - chromatin binding SPT4, Transcription elongation facto

CG6712 Drosophila Brix

1E-94 RNA binding nucleolus

IMP4 4E-034 btg1 0.11 IMP4, Predicted exosome subunit/U

RNA processing and -modification melanogaster - 1E-033 Brix-1e-033|Brix 4e-028| PRK03972 5e-006| BRX1 0.008| DUF859 | PRK10436 | PRK11621

ribosomal structure and biogenesis

1E-58

Translation,mitochondrial ribosomal protein S35 - Drosophila melanogaster - translation - structural constituent of ribosome - mitochondrial small ribosoma

ribosomal protein L18A Drosophila melanogaster - translation - 1e-056| RPL20ACADG

1E-67 Ribosomal_L18ae Ribosomal_L18ae 3E-057 3e-012| 0.39 RPL20A, ribosomal protein L20A (L

Translation,Ribosomal structure and -biogenesis 1E-056 Ribosomal_L18ae structural constituent of ribosome - cytosolic large Ribosomal subunit - riboso

ribosomal protein S8 - Ribosomal_S8e

5E-66 Drosophila melanogaster - translation - 8e-019| RPS8A

Ribosomal_S8e constituent of PRK04049 9e-008| RPS8A, Ribosomal protein lipid

Translation,Ribosomal structure and biogenesis 8E-019 Ribosomal_S8e structural2E-019 7e-013|ribosome - cytosolic small ribosomal subunit - S8E part

ribosomal - DrosophilaEF1G

4E-79 biogenesis 3E-040 EF1G 3e-040|EF1G 8E-041

Translation,Ef1gamma structure andmelanogaster - translational elongation - translation elongation factor activity - eukaryotic translation elongation factor

ribosomal protein S25 - biogenesis 2E-029 Ribosomal_S25 structural constituent of PRK09334 Ribosomal protein subunit - ribosom

4E-34 Ribosomal_S25 Ribosomal_S25 5E-030 5e-012| - cytosolic

Translation,Ribosomal structure and Drosophila melanogaster - translation -2e-029| COG4901 PINT ribosome0.12 0.003| small ribosomalS25

ribosomal protein S25 - biogenesis 5E-028 Ribosomal_S25 structural constituent of PRK09334 0.009| MarR | protein subunit - ribosom

3E-33 Ribosomal_S25 Ribosomal_S25 2E-028 3e-011| 0.074 Ribosomal

Translation,Ribosomal structure and Drosophila melanogaster - translation -5e-028| COG4901 PINT ribosome - cytosolic small ribosomalS25

ribosomal protein L3 - Drosophila melanogaster - translation - structural 7E-005 MUTSd

2E-63 rpl3p Ribosomal_L3constituent of ribosome -0.44 cytosolic large ribosomal subunit -

|

Translation,Ribosomal structure and biogenesis 5E-013 rpl3p 5e-013| Ribosomal_L3 2e-004| RplC 0.031| NOZZLE RplC, Ribosomal protein L3cytosolic

gawky - Drosophila melanogaster - nuclear-transcribed 0.028| PRK11281process,MukB | PRK03635 | mukB | PRK08316divisionGAL11 |protein,

Transcription 4E-39 CDC39 GAL11 0.19 CDC39, silencing | miRNA - cytop

0.028 CDC39 mRNA catabolic 0.093| nonsense-mediated decay - geneCell | FliJ bycontrol COG3

ribosomal protein L5 - Drosophila melanogaster - cytosolicRibosomal_L18p subunit - translation - structural constituent of ribosome - 5S

0 rpl18p large ribosomal2E-013 RplR, Ribosomal protein Fe-ADH |

Translation,Ribosomal structure and biogenesis 1E-018 rpl18p 1e-018| Ribosomal_L18p 9e-013| Ribosomal_L18_L5e 4e-012| RplR 2e-006|L18 rRNAP

Cell cycle control, cell division, chromosome partitioning HEC1, Protein involved in chromoso

ribosomal structure and protein L46 Drosophila melanogaster - Nudix_Hydrolase 0.002| Ap4A_hydrolase_plant_like 0.034| MutTsubunit PRK

2E-63 biogenesis NUP

Translation,mitochondrial ribosomalMRP_L46 -2E-037 MRP_L46 2e-037|structural0.68 MutT, NTP pyrophosphohydrolases

constituent of ribosome - mitochondrial large ribosomal 0.063|

ribosomal protein S9 - rps4p

9E-65 Drosophila melanogaster - translation - structural4E-007 S4of ribosome9E-006 RpsD, 4e-006| Ribosomal_S4 5e-00

S4 constituent - cytosolic small ribosomal subunit - ribosome

Translation,Ribosomal structure and biogenesis 4E-019 rps4p 4e-019| RpsD 1e-015| rpsD 2e-007| S4 1e-006| PRK12565 Ribosomal protein S4 and rel

PRK07764 DUF1682 0.28 TOPEUc 0.34 RPN2, 26S proteasome regulatory c

Translation, ribosomal structure and biogenesis 8E-004 PRK07764 8e-004| PRK05648 0.003| PRK05035 0.016| PRK07003 0.073| PRK12323 0.074| in

ribosomal structure - Rattus norvegicus - structural 1e-025| rps3p 2e-021| - protein binding cytoplasm - 0.018| rps3 | protein S3

2E-71 RpsC Ribosomal_S3_C 1E-020 AP2Ec 0.70 RpsC, Ribosomal

Translation,ribosomal protein S3and biogenesis 1E-025 RpsCconstituent of ribosomeRibosomal_S3_C-4e-020| rpsCcytosol - translation - translational e

ribosomal protein L8 - Drosophila melanogaster - translation - structural 2E-035

4E-98 rpl2p Ribosomal_L2_C constituent of ribosome - cytosolic large rpl2 7e-020| MD-1_MD-2

RplB, Ribosomal subunit -

Translation,Ribosomal structure and biogenesis 4E-059 rpl2p 4e-059| RplB 7e-052| Ribosomal_L2_C 7e-035| rplB 2e-023|ribosomal protein L2mitotic|sp

ribosomal factor02b - Drosophila melanogaster - translation - translation 3e-053| UAS activity 0.17 FusA, eEF2_snRNP_like_II -factors

PRK07560 EFG_IV elongation factor - cytoplasm - translational

Translation,Elongation structure and biogenesis 1E-057 PRK07560 1e-057| FusA 7E-007 aeEF2_snRNP_like_IV 9e-037|Translation elongation 5e-035| cytos

ribosomal structure - Rattus norvegicus - structural constituent of ribosome - protein binding - nucleolus -Uncharacterized protein conserved i

5E-67 Ribosomal_S7e Ribosomal_S7e

Translation,ribosomal protein S7and biogenesis 4E-070 Ribosomal_S7e 4e-070| COG4320 PSN 0.27

1E-070 | PRK06418 | PbpC | cytosol - ribosome - translational elo

ribosomal protein S19a Drosophila melanogaster - translation structural constituent of ribosome - cytosolic PRK09209 | COG1693 S19E (S

1E-62 Ribosomal_S19e Ribosomal_S19e RPS19A 3e-037| PRK09333 RPS19A, ribosomal protein riboso

Translation,Ribosomal structure and -biogenesis 7E-055 Ribosomal_S19e -7e-055|2E-055 HTH_DTXR 0.0101e-033| small Ribosomal subunit |-HTH_D

ribosomal protein S19a Drosophila melanogaster - translation structural constituent of ribosome - cytosolic PRK09209 | COG1693 S19E (S

7E-62 Ribosomal_S19e Ribosomal_S19e RPS19A 4e-037| PRK09333 RPS19A, ribosomal protein

Translation,Ribosomal structure and -biogenesis 8E-055 Ribosomal_S19e -8e-055|2E-055 HTH_DTXR 0.0301e-033| small Ribosomal subunit |- riboso

ribosomal protein L36 -Ribosomal_L36e

2E-39 biogenesis 4E-018 Ribosomal_L36e 4e-018| 1E-018 3e-009|

Ribosomal_L36e RPL36A Zn_pept 0.077 RPL36A, Ribosomal protein L36E

Translation,Ribosomal structure and Drosophila melanogaster - translation - structural constituent of ribosome - cytosolic large ribosomal subunit - ribosom

ribosomal protein L36 -Ribosomal_L36e

2E-46 biogenesis 8E-024 Ribosomal_L36e 8e-024| 2E-024 3e-011| ZnuC |0.073 RPL36A, Ribosomal protein L36E

Ribosomal_L36e RPL36A Zn_pept

Translation,Ribosomal structure and Drosophila melanogaster - translation - structural constituent of ribosome - cytosolic large ribosomal subunit - ribosom

ribosomal protein L18A Drosophila melanogaster - translation - 3e-070| RPL20A 2e-012|

2E-83 Ribosomal_L18ae Ribosomal_L18ae 1E-070 RPL20A, ribosomal protein L20A (L

Translation,Ribosomal structure and -biogenesis 3E-070 Ribosomal_L18ae structural constituent of ribosome - cytosolic large Ribosomal subunit - riboso

ribosomal protein L37A Drosophila melanogaster - translation - 3e-026| RPL43A 5e-016| rpl37ae - cytosolic large Ribosomal subunit - mitotic

5E-41 Ribosomal_L37ae Ribosomal_L37ae 9E-027 RPL43A, ribosomal protein L37AE/

Translation,Ribosomal structure and -biogenesis 3E-026 Ribosomal_L37ae structural constituent of ribosome 3e-014| PRK11788 | peptidase_C19C | PR

ribosomal protein S27 - biogenesis 3E-018 Ribosomal_S27e 3e-018| RPS27A 5e-014| rps27e0.14 RPS27A, Ribosomal protein

4E-39 Ribosomal_S27e Ribosomal_S27eribosome

of 1e-010|

Translation,Ribosomal structure and Drosophila melanogaster - structural constituent8E-019 ZP - cytosolic small ribosomal subunit - lipid particle S27E

Vacuolar H[+]-ATPase vATP-synt_E 1E-045 vATP-synt_E 1e-045| NtpE 3e-015| PRK03963 2e-009| PRK02292 0.001| ArpD |

4E-92 vATP-synt_E 3E-046 NtpE, Archaeal/vacuolar-type H+-AT

Energy production and conversion 26kD E subunit - Drosophila melanogaster - hydrogen-exporting ATPase activity, phosphorylative mechanism - vacuola

ribosomal structure rpl10e - translation - rpl10e 2e-044| Ribosomal_L16_L10e 4e-028| RplP 2e-026|subunit - ribosome - lipid particle -

melanogaster Ribosomal_L16 1E-017 POLXc 0.96 Ribosomal_L16 protein

Translation,Qm - Drosophila 0 and biogenesis 2E-044 structural constituent of ribosome - cytosolic large ribosomal RplP, Ribosomal 4e-017|L16/L10Em

0.001

Ribosomal protein L41 - Drosophila melanogaster - translation - structural constituent of ribosome - cytosolic large ribosomal subunit

Signal transduction mechanisms ModC 0.32 ModC | ModC, ABC-type molybdate transpo

ribosomal protein S30 - biogenesis, Posttranslational modification, protein turnover, chaperonessmall ribosomal subunit - UBQ 0.003| mitotic

9E-36 Ribosomal_S30 1E-018 Ribosomal_S30 1e-018| FubiribosomePRK09336 3e-004| Ribosomal protein S30

Ribosomal_S30 3e-013| -

of

Translation,Ribosomal structure and Drosophila melanogaster - structural constituent5E-019 UBQ cytosolic5E-005 COG4919 0.002| lipid particle -RAD23

ribosomal protein S16 - biogenesis 4E-025 rps9p 4e-025| Ribosomal_S9 2e-022| RpsI 2e-020| -rpsI 3e-010| rps9 3e-006| Alpha_L_fucospa

2E-50 rps9p Ribosomal_S9 constituent of ribosome cytosolic small ribosomal subunit - lipid 0.

5

Translation,Ribosomal structure and Drosophila melanogaster - translation - structuralE-023 RpsI, Ribosomal protein S9

ribosomal structure and biogenesis

5E-58

Translation,mitochondrial ribosomal protein S35 - Drosophila melanogaster - translation - structural constituent of ribosome - mitochondrial small ribosoma

ribosomal protein S8 - Ribosomal_S8e

7E-78 Drosophila melanogaster - translation - 8e-031| RPS8A

Ribosomal_S8e constituent of PRK04049 5e-016| RPS8A, Ribosomal protein lipid

Translation,Ribosomal structure and biogenesis 8E-031 Ribosomal_S8e structural2E-031 3e-022|ribosome - cytosolic small ribosomal subunit - S8E part

ribosomal protein L19 -Ribosomal_L19e_

9E-55 biogenesis 4E-029 Ribosomal_L19e_E 4e-029| Ribosomal_L19e 7e-022|

Ribosomal_L19e 9E-022 UAS - cytosolic large ribosomal subunit - L19E

RPL19A, Ribosomal RPL19A 8e-01

Translation,Ribosomal structure and Drosophila melanogaster - translation - structural constituent of ribosome0.25Ribosomal_L19e 3e-021|protein ribosom

ribosomal protein L27A Drosophila melanogaster - 1e-008| RplO 5e-006| L15 8e-005| ribosome cytosolic large ribosomal subunit - riboso

1E-37 rpl15p L15 2E-005 IL2 0.007 RplO, 0.003| RPL18A 0.024|

Translation,Ribosomal structure and -biogenesis 1E-008 rpl15ptranslation - structural constituent ofPRK04005- 0.002| rplO Ribosomal protein L15 IL2 | PR

ribosomal factor0Tu mitochondrial - 1E-136 melanogaster - translational e-133| PRK12736 e-127| TufB e-125| tufA e-118| EF_Tu e-100|

PRK00049 GTP_EFTU 8E-057 PROF 0.33 TufB, GTPases - translation elongat

Translation,Elongation structure and biogenesis DrosophilaPRK00049 e-136| PRK12735elongation - translation elongation factor activity - mitochondrion P

ribosomal structure - Mus musculus laminin binding

3E-79 Ribosomal_S2 Ribosomal_S2 E-059 DM11

5 0.79 RpsB, rps2 0.008| rpsB S2

Translation,ribosomal protein SAand biogenesis 2-E-058 Ribosomal_S2 2e-058| rps2P 3e-044| RpsB 2e-037| rpsB 1e-008|Ribosomal protein0.021| aceF

MCPVI 0.51 alkPPc 0.48

gryzun 1E-33 DUF1683 2E-025 DUF1683 learning DUF1683 memory olfactory learning

Function unknown - Drosophila melanogaster - cellular_component - 2e-025| and/or6E-026 -INB 0.039 Beta-propeller domains of methanol

ribosomal structure andRattus norvegicus

1E-40 biogenesis 1E-025 Ribosomal_L31e 1e-025| 3E-026 2e-014| PRK01192 2e-010| RIO1_euk |

- cytosol - translational Tryp_SPc

Translation,ribosomal protein L31 - Ribosomal_L31e - protein binding Ribosomal_L31e RPL31A elongation 0.50 RPL31A, Ribosomal protein L31E

ribosomal structure and biogenesis

4E-36 - translation 0.81 translation initiation (light-regulated

Translation,CG9769 - Drosophila melanogaster - translational initiation DUF1290 initiation factor activity - eukaryoticBacteriophytochromefactor 3 comple

ribosomal protein L24 -MM_CoA_mutase_a MM_CoA_mutase_alpha_like |

4E-23 biogenesis 0.58 MM_CoA_mutase

Translation,Ribosomal structure and Drosophila melanogaster - translation - structural 0.35constituent of ribosome - cytosolic large ribosomal subunit - lipid par

ribosomal protein S3A Ribosomal_S3Ae

3E-61 - Drosophila 2E-041 Ribosomal_S3Ae 2e-041|7E-042 1e-025| PRK04057cytosolic small ribosomal protein - oogene

Ribosomal_S3Ae RPS1A RL11 - 2e-015| PRK08267 |

Translation,Ribosomal structure and biogenesis melanogaster - translation - structural constituent of ribosome0.45 RPS1A, Ribosomal subunit S3AE

ribosomal structure and biogenesis, 3E-014 GatA 3e-014| PRK06170-8E-012 gatA 3e-012| Amidase GatA, Asp-tRNAAsn/Glu-tRNAGln a

6E-45 GatA fatty acid amide hydrolase activity 9e-014| HYDRO

Amidase lipid particle 0.014

Translation,CG8839 - Drosophila melanogaster -Lipid transport and metabolism, Signal transduction mechanisms 3e-011| PRK08310 8e-011| PRK07488

ribosomal protein L9 - Drosophila melanogaster - translation - structural 1E-009 CPDc

5E-44 rpl6p Ribosomal_L6constituent of ribosome cytosolic large ribosomal subunit - ribosome

Translation,Ribosomal structure and biogenesis 5E-014 rpl6p 5e-014| RplF 5e-010| Ribosomal_L6 4e-009|-0.60 RplF, Ribosomal protein L6P/L9E



Calcium ATPase0at 60AMgtA- Drosophila 4E-068 MgtA 4e-068| Cation_ATPase_C 2e-034| PRK10517 1e-024| ZntA 2e-019| zntA 8e-014| PRK10

Inorganic ion transport and metabolism Cation_ATPase_C

6E-035 activity - endoplasmic reticulum - calcium ion transport - end

melanogaster - calcium-transporting ATPase MA 0.96 MgtA, Cation transport ATPase

Lipid transport and metabolism, Intracellular trafficking, secretion, and vesicular transport

General function prediction only COG3264 V_ATPase_I 0.44

0.023 COG3264 0.023| COG4372 | COG2433 | PRK08993 | PRK02224 | Small-conductance mechanosensitiv

G protein beta-subunit WD40

0 7E-032 WD40 - G-protein coupled receptor protein signaling pathway - eIF2A | activity

WD40 1e-015| WD40 WD40 FOG: WD40

General function prediction only 13F - Drosophila melanogaster7e-032| COG2319 3E-005 WD40 4e-005| 5E-0071e-004| GTPaserepeat - heterotrimeric

GPR89A, GPR89, GPR89B,

1E-82 0.69 LAP4 | LAP4, Aspartyl aminopeptidase

Signal transduction mechanisms LAP4CGI-13, SH120, HSPC201, UNQ192/PRO218: Protein GPR89 - Homo sapiens - signal transducer activity - positi

SNF1A/AMP-activated PRK04293

6E-63 Drosophila melanogaster - protein amino acid Uncharacterized - G-protein coupled

Lipid transport and metabolism protein kinase -0.69 PRK04293 | PRK08332 | PRK10420 | phosphorylation - signal transduction protein conserved i

Sac1 - metabolism0 COG5329 2E-063 COG5329 2e-063| Syja_N 9e-026|

Syja_N 2E-026 Phosphoinositide polyphosphatase (

Lipid transport and Drosophila melanogaster - polyphosphoinositide phosphatase activity - dorsal closure - dorsal closure, amnioserosa morphology chang

Cad96Ca - Drosophila PTKc

0 - protein PTKc 5e-091| PTKc_FGFR protein Pkinase_Tyr 4E-081 TyrKc 4e-079| PTKc_FGFR1protein ty

Pkinase_Tyr 3E-081 tyrosine 1e-080| - transmembrane receptor 3e-070|

Signal transduction mechanisms melanogaster 5E-091 amino acid phosphorylation -3e-082|TyrKc kinase activitySPS1, Serine/threonine protein kina



trafficking, secretion, Drosophila melanogaster - RNA binding - cytoplasm0.45

1E-11 PRK12323 0.001 Herpes_LMP2 - 0.060| binding

Intracellular quaking related 54B - and vesicular transport PRK12323 0.001| PRK08853mRNARPOL4c 0.52 Predicted membrane PRK09111 | C

PRK07764 0.083| PRK05648 | PRK10218 | protein

Transcription 8E-46 TFIID_20kDa3E-022 TFIID_20kDa 3e-022| TAF61 1e-021| L-fuc_L-ara-isomerases | HHT1 |

TFIID_20kDa1E-022 TAF61, Transcription initiation factor

TBP-associated factor 12 - Drosophila melanogaster - regulation of transcription, DNA-dependent - nucleus - transcription initiation from RNA p

cereblon - Rattus norvegicus

8E-29 0.27 GcvT

General function prediction only IlvC - protein binding IlvC | LON | LON | 0.11 IlvC, Ketol-acid reductoisomerase

CG8801 - Drosophila NOGCT

9E-94 GTP binding - nucleus

NOGCT 2E-013 G_alpha 0.25 Predicted GTPase

General function prediction only melanogaster - 8E-013 NOGCT 8e-013| NOG 3e-011| Obg_like 6e-004| obgE 6e-004| obgE 0.001| Obg 0.001| COG10



CG13907 - and metabolism

3E-59 MFS_1 - secondary active monocarboxylate transmembrane transporter activity

MFS_1 9E-005 Permeases of the major facilitator

Carbohydrate transport Drosophila melanogaster 3E-004 MFS_1 3e-004| COG2270 0.053| DNA_topoisoIV 0.060| AraJ 0.060| FucP | PRK05777 | fliF | su

CG6180 - Drosophila RKIP

3E-36 phosphatidylethanolamine binding 9E-021

PBP | PEBP |

General function prediction only melanogaster - 3E-027 RKIP 3e-027| PBP 3e-020| PEBP_RKIP 2e-012| COG1881Phospholipid-binding protein

Mitochondrial phosphate carrier protein - Drosophila melanogaster - phosphate transport - phosphate transmembrane transporter activity - mit

1E-89

Energy production and conversion Mito_carr Mito_carr 3E-013

1E-012 Mito_carr 1e-012| PRK04452 | CheW | CheW, Chemotaxis signal transduct

VhaPPA1-1 - Drosophila melanogaster - hydrogen-exporting ATPase activity, phosphorylativePRK06271 0.065| PRK06251 ATP synthase,EscV

8E-63

Energy production and conversion AtpE PRK08344 0.014 G_alpha 0.48 - vacuolar proton-transporting sub

0.009 AtpE 0.009|Ail_Lom 0.043| Ail_Lom 0.047| mechanismAtpE, F0F1-type | PRK06558 |V-typ

hATC hATC

0.18 hATC | Peptidase_C19E | 0.057 KpsC, Capsule polysaccharide expo

COG4920

Replication, recombination and repair 0.26 COG4920 | EXOIII | EXOIII 0.009 Predicted membrane protein

CG1732 - Drosophila SNF

9E-46 gamma-aminobutyric SNFCOG0733 symporter activity

7E-027

Signal transduction mechanisms melanogaster - 2E-026 SNF 2e-026|acid:sodium2e-004| MarC | Na+-dependent transporters of the S

Ferritin 2 light 6E-33homologue - Drosophila melanogaster Ferritin Ferritin 1e-012| Ferritin ferrous iron binding -| ferritin complex histidine ki

chain Euk_Ferritin 2E-019 Euk_Ferritin-2e-019| iron 2E-005 LamNT - 8e-005| PRK06701 Signal transduction

Inorganic ion transport and metabolism cellular ion homeostasis 0.067 CitA, PRK08270 |

Na pump alpha subunit MgtA

0 - Drosophila melanogaster - sodium:potassium-exchanging ATPase activity - nucleus - plasma membraneATPase

Inorganic ion transport and metabolism Cation_ATPase_C

8E-037 MgtA, Cation transport - response t

5E-043 MgtA 5e-043| Cation_ATPase_C 3e-036| ZntA 2e-009| PRK10517 3e-009| zntA 3e-004| PRK10

Retinoid- 4E-48 VWD 6E-005 VWD 6e-005| VWD 7e-004| DUF953 | C8 ComFC |

VWD retinol VWD 7E-007 ComFC, transport lipid transporter

Function unknown and fatty acid-binding glycoprotein - Drosophila melanogaster -2E-004 binding - |extracellular region - lipid Predicted -amidophosphorib

polymerase (DNA-directed),

8E-92 DUF525 1E-044 DUF525 1e-044| apaG - 4E-045

DUF525 mitochondrion - protein ApaG,

Inorganic ion transport and metabolism delta interacting protein 2 - Mus musculus8e-030| ApaG 3e-024| binding, bridgingUncharacterized protein affec

General function prediction only AF-4 AF-4 3E-005 VWD 3E-006 RNA-binding 0.005| of the Puf famil

1E-004 AF-4 1e-004| VWD 2e-004| Herpes_gp2 0.002| SSP160 0.002| DUF601 protein DNA_pol_viral_



Arabidopsis thaliana - biological_process - cellular_component - molecular_function

Function unknown 3E-24 DUF647 2E-034 DUF647 2e-034|DUF647 7E-035 NTR 0.49

Arabidopsis thaliana - biological_process - cellular_component - PTKc_Frk_like | INB

Function unknown 3E-23 DUF647 DUF647 9E-035

3E-034 DUF647 3e-034| molecular_function 0.33

General function prediction only DUF629 DUF629 0.071

0.24 DUF629 | EF-G | Myco_haema | IFabd 0.60

cirrhosis, autosomal COG3662

2E-07 0.60 COG3662 | WD40 0.071 Uncharacterized

General function prediction only recessive 1A (human) - Mus musculus - biological_process - cellular_component - molecular_function protein conserved i

CG3714 and metabolism

2E-55 PRK09243 nicotinate phosphoribosyltransferase0.31

Prominin activity

Coenzyme transport - Drosophila melanogaster - 8E-012 PRK09243 8e-012| PRK12484 5e-005| PRK08662 0.073| PRK05297 | Prominin |

Cytoskeleton PRK03918 PRK00409 | Apolipoprotein | COG1139 |

0.14 PRK03918 |Apolipoprotein0.080 Uncharacterized conserved protein c

PRK06464 0.59 PRK06464 |MED7 0.36 Cullin, a subunit of E3 ubiquitin ligas

CG8446 and metabolism

3E-24 lplA 0.002 lplA 0.002|

Coenzyme transport - Drosophila melanogaster - lipoyltransferase activity

CG3760 - Drosophila melanogaster - molecular_function - cellular_component - biological_process

8E-10

Secondary metabolites biosynthesis, transport and catabolism Uncharacterized protein predicted to

GE14456: biosynthesis, transport Drosophila yakuba cellular_component - biological_process - molecular_function

1E-14 CDC45 catabolism

Secondary metabolitesProtein CDV3 homolog -and0.16 CDC45 |- RpoD | CDC45 0.044 HOLI 0.14 RpoD, DNA-directed RNA polymera

2E-10 DUF481 0.78

CG2182 - Drosophila melanogaster - molecular_function - cellular_component - biological_process

transmembrane protein DUF92 musculus - integral to0.058| COG1836 0.078| COG0182 |

Function unknown 1E-23 19 - Mus 0.058 DUF92 membraneDUF92 0.017 Predicted membrane protein

conserved hypothetical DUF1989Silicibacter pomeroyi DSS-3 - molecular_function - cellular_component - biological_process

Transcription 1E-20 protein - DUF1989 8E-023

3E-022 DUF1989 3e-022| COG3665 4e-017| Uncharacterized conserved protein

Cytoskeleton SKN1 0.75

isochorismatase domain containing 1 - Danio YcaC_related 5e-039| cysteine_hydrolases

7E-39 Isochorismatase 0.41 PncA, Amidases related to nicotinam

General function prediction only YcaC_related5E-039 rerio - cellular_component 1E-008 SEC14 2e-015| Isochorismatase 4e-008| PncA 0.001| nicot

RCJMB04_2c17: Putative uncharacterized protein - Gallus DER1 - protein binding - MHC class I protein binding - ER-associated protein catab

Function unknown 8E-37 DER1 gallus

3E-023 DER1 3e-023| COG5291 9E-0243e-008| Predicted membrane protein

CBM_14 0.68 CBM_14 | CBM_14 0.20 ChtBD2 0.071









0.00002 Attacin_C - biological_process -Attacin_C 2E-004 cellular_component

molecular_function - BID_1

CG33493 - Drosophila melanogaster 7E-004 Attacin_C 7e-004| 0.49

LIF_OSM LIF_OSM

0.28 LIF_OSM | PRK07042 | 0.090

Signal transduction mechanisms WT1 0.93 KdpD, Osmosensitive K+ channel hi

Extracellular structures Ebola_NP 0.10

RPA1_DBD_C0.100 RPA1_DBD_C 0.100| Ebola_NP | CPDc 0.23

LacZ, Beta-galactosidase/beta-glucu

Peptidase_S390.26 Peptidase_S39 | PRK08257 | PRK12678 |

Signal transduction mechanisms, Cytoskeleton Peptidase_S39 0.083

coiled-coil 5E-35 DUF1014 2E-018 - biological_process DUF1014 7E-019 TOPEUc 0.13 Predicted Zn-dependent

Function unknown domain containing 124 - Danio rerio DUF1014 2e-018| PRK11281 0.046| COG1026 0.084| U79_P34 | M16C_assoc | peptidases,

PRK12566 0.28 PRK12566 |Gasdermin | 0.77

PRK01497

Signal transduction mechanisms, Chromatin structure and dynamics, Replication, recombination and repair, Cell cycle control, cell division, chromosome p

Peroxidasin - Drosophila melanogaster0.33 OspD | COG4886 | matrix - peroxidase activity 0.34 Leucine-rich repeat (LRR) protein

0.0004

Signal transduction mechanisms OspD OspD

- proteinaceous extracellular 0.093 SynN

integral 1E-08 BRICHOS 6E-015 BRICHOS BRICHOS 2E-015 G_alpha

Function unknown membrane protein 2A - Mus musculus - integral to6e-015| membrane 0.31 Uncharacterized protein conserved i

nimrod mechanisms

2E-14

Signal transduction B2 - Drosophila melanogaster - mesoderm development - extracellular region SEC63 0.098

0 Retrotrans_gag .004 HLH

0 Myc_N MAK16, Nuclear protein with | PRK

General function prediction only Retrotrans_gag .015 Retrotrans_gag 0.015| MAK16 0.018| AF-4 0.038| 0.11 0.077| DUF755 0.090| SelP_NHMG-li

trafficking, 11 - Drosophila melanogaster - GTPase activity - oogenesis 3E-031binding - regulation1e-027|GTPase SAR1 Rab4 localization -G p

1E-66 Rab11_like 3E-047

Intracellular Rab-proteinsecretion, and vesicular transport Rab11_like Ras - GTP RAB 2E-038 plasm oskar mRNA 4e-025| Rab1_

3e-047| RAB 1e-036| Ras 1e-030| Rab of pole Rab2 5e-026| and related small en

Best

Best Best match to

match to match to AEGY-

General PRK CP-PEP Extent of PEP % Match

E value class database E value database match % identity database E value % identity length









CPIJ014551-PA 284 88 3.00E-40

D7 protein, putative 32 92

CPIJ014551-PA 313 86 2.00E-47

D7 protein, putative 33 100

CPIJ014551-PA 266 86 6.00E-37

D7 protein, putative 32 84

0.39 CPIJ014551-PA

Amino acid transport and metabolism 313 31 3.00E-34

D7 protein, putative 27 102

CPIJ014551-PA 313 31 4.00E-36

D7 protein, putative 28 102

CPIJ014551-PA 270 31 3.00E-30

D7 protein, putative 28 84

0.030 General function prediction only CPIJ014547-PA 156 65 1.00E-04

D7 protein, putative 26 39

0.86

enoyl-CoA hydratase. CPIJ014551-PA 204 25 3.00E-91

D7 protein, putative 65 82

CPIJ010787-PA 149 71 6.00E-25

conserved hypothetical protein 38 93

0.75 CPIJ017326-PA

Amino acid transport and metabolism 95 95 5.00E-47 83

Odorant-binding protein 99c, putative 69



0.062 N-acetylmuramoyl-L-alanine amidase.

0.022 CPIJ002046-PA 224 71 conserved hypothetical

dynamics

Transcription / DNA replication, recombination, and repair / Chromatin structure and 7.00E-19 protein 27 90

0.062 N-acetylmuramoyl-L-alanine amidase.

0.002 CPIJ002046-PA 229 71 conserved hypothetical

dynamics

Transcription / DNA replication, recombination, and repair / Chromatin structure and 1.00E-18 protein 26 90

0.068 N-acetylmuramoyl-L-alanine amidase.

Coenzyme metabolism 0.018 CPIJ002046-PA 230 1.00E-18

71 conserved hypothetical protein 27 90

0.25 Function unknown CPIJ003615-PA 214 5.00E-19

90 hypothetical protein 34 65

0.26 sensory 0.83 in two-component regulatory system with BaeR.1.00E-19

Function unknown histidine kinaseCPIJ003615-PA 214 89 hypothetical protein 35 65

0.17 Function unknown CPIJ003615-PA 214 1.00E-19

91 hypothetical protein 36 61

2E-005 transcription termination factor Rho.

only

General function prediction0.11 CPIJ002646-PA 251 9.00E-32

68 conserved hypothetical protein 33 99

1E-004 RNA prediction 0.4only

General function polymerase sigmaCPIJ002646-PA 255

factor RpoD. 2.00E-29

70 conserved hypothetical protein 30 99



2E-005 3'-cyclic nucleotide

0.089 CPIJ010045-PA 68 54 conserved 2.00E-12

General function prediction only2'-phosphodiesterase/3'-nucleotidase bifunctional hypothetical protein 30 82

9E-006 3'-cyclic nucleotide

0.062 CPIJ010045-PA 77 55 conserved 6.00E-13

General function prediction only2'-phosphodiesterase/3'-nucleotidase bifunctional hypothetical protein 30 80

0.022 N-acetylmuramoyl-L-alanine amidase.

only

General function prediction0.45 CPIJ012373-PA 246 1.00E-100

86 virus-induced RNA, putative 68 99

0.72 Function unknown CPIJ018872-PA 123 9.00E-08

86 conserved hypothetical protein 31 39





3E-068 trehalose-6-phosphate hydrolase.

4E-76 CPIJ016362-PA

Carbohydrate transport and metabolism 584 89 alpha-amylase 0 73 100

9E-008 trehalose-6-phosphate hydrolase.

5E-12 CPIJ016362-PA

Carbohydrate transport and metabolism 325 81 1.00E-113

alpha-amylase 63 56

0.27 CPIJ005064-PA

Nucleotide transport and metabolism 143 89 5

alpha-amylase.00E-58 66 29

8E-010 cytoplasmic alpha-amylase.

0.002 CPIJ017521-PA

Carbohydrate transport and metabolism 297 89 1.00E-128

alpha-amylase 70 40

6E-012 cytoplasmic alpha-amylase.

0.002 CPIJ005064-PA

Carbohydrate transport and metabolism 225 92 1.00E-102

alpha-amylase 76 45



hypothetical metabolism

0.83

2E-006 Nucleotide transport andprotein. CPIJ003384-PA 234 1.00E-112

94 deoxyribonuclease I, putative 77 56



CPIJ001263-PA 101

8E-005 Inorganic ion transport and metabolism 5.00E-48

44 alkaline phosphatase 62 26



serine endoprotease. CPIJ019291-PA 127

0.0004

4E-009 Posttranslational modification, protein turnover, chaperones 65 2.00E-55

serine protease htra2 83 30

L-aspartate oxidase. CPIJ017793-PA 299

0.42

3E-016 Posttranslational modification, protein turnover, chaperones 94 1.00E-152

serine protease 80 70

CPIJ020192-PA 259 61 1.00E-43

conserved hypothetical protein 41 74

CPIJ014952-PA 106

5E-004 Posttranslational modification, protein turnover, chaperones 82 4.00E-37

Trypsin, putative 64 26

CPIJ019882-PA 94

8E-010 Posttranslational modification, protein turnover, chaperones 94 1.00E-25

serine protease 57 31

CPIJ017729-PA 111

3E-009 Posttranslational modification, protein turnover, chaperones 2.00E-49

71 serine protease 79 42



CPIJ005450-PA 148 2.00E-62

91 lysozyme P, putative 76 92

CPIJ006809-PA 78 3.00E-21

71 serine protease, putative 56 16

ferric iron-catecholate outer

0.72 CPIJ004231-PA 286

2E-010 Carbohydrate transport and metabolismmembrane transporter. 1.00E-139 76

68 gram-negative bacteria binding protein 77









CPIJ018300-PA 171 1.00E-61

94 allergen, putative 64 80

CPIJ004029-PA 137 91 venom allergen2.00E-48 59 53





0.12 CPIJ019874-PA 113 93 3.00E-52 protein 2 precursor, putative

predicted propionyl-CoA synthetase with ATPase domain. WAP four-disulfide core domain 79 100

0.13 CPIJ019874-PA 113 94 3.00E-52 protein 2 precursor, putative

predicted propionyl-CoA synthetase with ATPase domain. WAP four-disulfide core domain 79 100





0.040 sec-independent translocase.

only

General function prediction0.68 CPIJ008900-PA 336 6.00E-68

74 conserved hypothetical protein 39 101





0.091 Function unknown CPIJ015714-PA 207 2.00E-38

86 conserved hypothetical protein 40 97



CPIJ012060-PA 205 0.092

28 slender lobes, putative 20 17





0.11 CPIJ007741-PA 246 9.00E-43

anaerobic ribonucleotide reductase-activating protein. 82 conserved hypothetical protein 35 93

0.16 phosphoribosylaminoimidazole-succinocarboxamide synthase.

0.11 CPIJ007742-PA 232

Nucleotide transport and metabolism 1.00E-38

84 conserved hypothetical protein 34 87

0.29

phosphotransacetylase.CPIJ007742-PA 232 5.00E-40

84 conserved hypothetical protein 35 87

CPIJ007742-PA 231 4.00E-38

85 conserved hypothetical protein 34 87

0.81 Cytoskeleton CPIJ007742-PA 235 2.00E-38

83 conserved hypothetical protein 34 87

0.47 Cytoskeleton 0.68 CPIJ007742-PA 182

ATP-dependent RNA helicase DeaD. 2.00E-30

82 conserved hypothetical protein 35 69



CPIJ006741-PA 101 2.00E-06

24 conserved hypothetical protein 34 67



CPIJ008470-PA 21 0

57 hypothetical protein.39 33 97

0.83 CPIJ008470-PA

Nuclear structure / Intracellular trafficking and secretion 21 0

57 hypothetical protein.17 36 97

0.59 CPIJ001232-PA 28

potassium-tellurite ethidium and proflavin transporter. 42 hypothetical protein1.1 36 3





0.043 elongation and P. CPIJ013702-PA

0.074

Carbohydrate transportfactormetabolism 164 76 0.42 25 28

dual-specificity protein phosphatase, putative

0.18 elongation and P. CPIJ013702-PA

0.07

Carbohydrate transportfactormetabolism 164 76 0.42 25 28

dual-specificity protein phosphatase, putative

0.60 preprotein translocase CPIJ019050-PA

only

General function prediction0.18 subunit SecA. 114 76 0.23

conserved hypothetical protein 28 10

0.15 Energy production and conversion CPIJ019052-PA 160 73 coatomer 0.88 31 4

CPIJ005738-PA 165 86 1.00E-12

hypothetical protein 32 90

0.16 General function prediction only CPIJ019040-PA 157 59 0

hypothetical protein.39 23 46

CPIJ019051-PA 156 85 1.1

conserved hypothetical protein 32 12

0.41 General function prediction only CPIJ019040-PA 99 61 1.1 35

phosphoribosylamine-glycine ligase 3

CPIJ010517-PA 137 86 1.1

antifreeze protein, putative 28 60

0.059 Nucleotide transport and metabolismCPIJ010792-PA 136 44 8.00E-04

conserved hypothetical protein 33 22

0.45 8-amino-7-oxononanoate

0.73 CPIJ010792-PA

Nucleotide transport and metabolism synthase. 136 44 0.011

conserved hypothetical protein 32 22

0.058 Nucleotide transport and metabolismCPIJ010792-PA 136 42 0.002

conserved hypothetical protein 33 21

0.54 Coenzyme metabolism CPIJ010792-PA 136 2.00E-04

45 conserved hypothetical protein 33 21

0.92 General function prediction only CPIJ010792-PA 136 0.003

45 conserved hypothetical protein 31 21

0.94 CPIJ001841-PA 137 69 macroglobulin/complement

0.41

bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon. 34 5

CPIJ019056-PA 90 0.009

56 conserved hypothetical protein 29 18

0.035 8-amino-7-oxononanoate

0.056 CPIJ010792-PA 117

Nucleotide transport and metabolism synthase. 0.01

46 conserved hypothetical protein 32 21

0.49 CPIJ019055-PA 91

Inorganic ion transport and metabolism 0.027

52 hypothetical protein 33 40

0.27 Function unknown CPIJ019053-PA 99 8.00E-04

56 hypothetical protein 30 48

0.033 8-amino-7-oxononanoate

0.15 CPIJ010792-PA 132

Nucleotide transport and metabolism synthase. 0.011

43 conserved hypothetical protein 32 21



CPIJ008479-PA 63 0

82 hypothetical protein.17 43 8

CPIJ006133-PA 73 0.66

28 conserved hypothetical protein 38 9



0.62 hypothetical 0.005

Coenzyme metabolism protein. CPIJ002236-PA 135 4.00E-06

34 transcription factor, putative 36 33

0.034

hypothetical protein. CPIJ002236-PA 100 43 fibrillarin 4.00E-06 39 24

0.003 CPIJ002236-PA 118

transcription termination factor Rho. 9.00E-08

40 collagen alpha chain, anopheles35 7





1E-061 Cytoskeleton CPIJ009808-PA 221 99 actin 1.00E-125 99 59

5E-091 Cytoskeleton 0.37 CPIJ009808-PA

short chain dehydrogenase. 302 99 actin 1.00E-174 99 80

1E-012 ribosomal structure L23.

protein CPIJ000279-PA

Translation,50S ribosomal5E-11 and biogenesis 208 93 2.00E-05

histone H1, putative 42 37

0.040 ribonuclease 0.0002membrane

Cell envelope biogenesis,E. outer CPIJ012583-PA 98 87 3.00E-24

hypothetical protein 51 47

1E-016 CPIJ005306-PA

Cell division and chromosome partitioning 245 90 4.00E-79 96 55

restin (cytoplasmic linker protein-170) (clip-170)

CPIJ006739-PA 105 99 1.00E-59

dynein light chain, putative 100 95



DNA polymerase III CPIJ011200-PA 339

2E-004 Coenzyme metabolism 0.006subunits gamma and tau. 59 2.00E-28

predicted protein 29 27

DNA polymerase III CPIJ011200-PA 260

0.003 Coenzyme metabolism 0.002subunits gamma and tau. 65 3.00E-27

hypothetical protein 34 13

amidophosphoribosyltransferase.

metabolism

0.11 Inorganic ion transport and 0.4 CPIJ002167-PA 148 27 4.00E-10

chondroitin 4-sulfotransferase 23 53

0.24

hypothetical protein. CPIJ016691-PA 128 89 1.00E-33

matrix metalloproteinase 49 26

0.13 Transcription CPIJ005118-PA 170 89 1.00E-51

fasciclin, putative 60 45

0.74 CPIJ008003-PA 133

30S ribosomal protein S3Ae. 94 annexin x 1.00E-62 85 41



0.26 CPIJ006792-PA

predicted methyltransferase. 97 5.00E-25

80 Spatzle 1B (Spz1B) 53 38



3E-004 Lipid metabolism CPIJ001121-PA 153 92 1.00E-52

conserved hypothetical protein 66 49

0.064 Amino acid transport and metabolismCPIJ001052-PA 279 86 zinc metalloprotease

protease m11.00E-109 64 31

7E-009 DNA-directed RNA polymerase subunit K. 131

Transcription 1E-11 CPIJ018444-PA 98 RNA polymerase 96

DNA-directed3.00E-71 100

subunit rpb6

0.17 Function unknown CPIJ003974-PA 161 81 3.00E-47

conserved hypothetical protein 77 17

0.079 6-phosphogluconate dehydrogenase.

Function unknown 0.81 CPIJ013872-PA 106 88 3.00E-18

hypothetical protein 51 35

0.001 transport and metabolism

1E-08

Amino acid hypothetical protein. CPIJ017373-PA 106 98 1.00E-53

glutamate carboxypeptidase 91 22

2E-016 transport dehydratase. CPIJ011198-PA 149

2E-28

Amino acid threonine and metabolism 97 1.00E-74

threonine dehydratase/deaminase89 32

1E-067 transport and metabolism

1E-65 CPIJ014981-PA 291

Amino acid glycine cleavage system aminomethyltransferase T. 94 1.00E-149

aminomethyltransferase 89 71

0.43

hypothetical protein. CPIJ018340-PA 103 88 4.00E-29

conserved hypothetical protein 67 38



2E-039 glycogen branching enzyme.

8E-26 CPIJ006166-PA 323

Carbohydrate transport and metabolism 95 1.00E-180

starch branching enzyme ii 90 47

1E-062 hydroxypyruvate isomerase.

4E-46 CPIJ007381-PA 212

Carbohydrate transport and metabolism 86 6.00E-93

conserved hypothetical protein 72 77

8E-066 galactokinase.7E-63 CPIJ015186-PA 232

Carbohydrate transport and metabolism 87 1.00E-106

galactokinase 81 58

3E-031 glucosamine-6-phosphate deaminase. 115

8E-08 CPIJ008074-PA

Carbohydrate transport and metabolism 27 3.00E-83

6-phosphogluconolactonase 80 73

CPIJ000349-PA 305 88 1.00E-140 77

glucosyl/glucuronosyl transferases 58

CPIJ006068-PA 155

2E-016 Carbohydrate transport and metabolism 98 3.00E-84 98 2

utp-glucose-1-phosphate uridylyltransferase30

glyceraldehyde-3-phosphate

3E-24 CPIJ005597-PA 99

4E-034 Carbohydrate transport and metabolism dehydrogenase. 97 cyclase

soluble guanylate 0.22 gcy 36 5

0.040 CPIJ001782-PA 208

Amino acid transport and metabolism 98 importin 1.00E-104 84 21



3E-045 malate dehydrogenase.

5E-82

Energy production and conversion CPIJ008366-PA 235 1.00E-122

97 malate dehydrogenase 94 56

0.69 Energy production and conversion CPIJ000484-PA 104 8.00E-52

97 symbol, putative 86 64

8E-080 3-hydroxybutyryl-CoA dehydrogenase. 270

Lipid metabolism 9E-68 CPIJ006479-PA 1.00E-139

97 3-hydroxyacyl-coa dehyrogenase 88 89

1E-051 F0F1 ATP conversion CPIJ006209-PA 115

8E-56

Energy production andsynthase subunit beta. beta subunit

97 atp synthase 2.00E-58 97 23

1E-155 F0F1 ATP conversion CPIJ006209-PA 313

1E-163

Energy production andsynthase subunit beta. 1.00E-166

95 atp synthase beta subunit 97 61

5E-014 General function prediction only CPIJ011929-PA 279 1.00E-123 78 63

95 ubiquinol-cytochrome c reductase complex core protein

0.40 heat 0.43

Transcription shock protein 70. CPIJ006067-PA 162 atp synthase b chain

97 mitochondrial7.00E-81 90 68

4E-004 Energy production and conversion CPIJ012341-PA 87 94 malic enzyme4.00E-40 83 13

3E-061 malic enzyme.1E-23

Energy production and conversion CPIJ012341-PA 306 97 malic enzyme 1.00E-170 93 46

0.11 multidrug resistance outer membrane protein

0.11 3.00E-53

Energy production and conversion CPIJ004713-PA 107MdtQ. 98 conserved hypothetical protein 84 101

CPIJ009076-PA 102 1.00E-46

93 conserved hypothetical protein 83 100

0.35 aerobic respiration control sensor protein ArcB.

Transcription 0.46 CPIJ006067-PA 139 atp synthase b chain

97 mitochondrial8.00E-68 89 58

0.011 Transcription

Chromatin structure and dynamics /CPIJ017724-PA 268 4.00E-96

83 conserved hypothetical protein 69 48

5E-039 F0F1 ATP conversion CPIJ001563-PA 218

5E-39

Energy production andsynthase subunit gamma. 1.00E-108

90 atp synthase gamma subunit 87 73

0.12 CPIJ011269-PA 148 NADH:ubiquinone76

cryptic autophosphorylating protein tyrosine kinase Etk. 91 mitochondrial1.00E-63 88

oxidoreductase B14.7 subunit, putative

5E-042 ribosomal structure S5P.

protein CPIJ010326-PA 222

Translation,30S ribosomal1E-61 and biogenesis 1.00E-134

99 40S ribosomal protein S2 99 87

0.005 electron transport complex protein

0.000004 CPIJ018780-PA

Cell envelope biogenesis, outer membrane RnfC. 203 1.00E-98

52 ribosomal protein S6 83 67

4E-022 5-methylcytosine-specific restriction enzyme subunit McrB. hexokinase 2.00E-94

0.63 CPIJ008049-PA 175

Carbohydrate transport and metabolism 98 97 38

0.11 General function prediction only CPIJ011929-PA 187 2.00E-76 75 43

90 ubiquinol-cytochrome c reductase complex core protein

2E-030 type I and conversion

3E-56

Energy productioncitrate synthase. CPIJ019861-PA 146 2.00E-79

98 citrate synthase 97 31

3E-032 succinyl-CoA synthetase subunit alpha.

2E-18

Energy production and conversion CPIJ000859-PA 316 98 atp-citrate synthase 0 98 28

CPIJ014797-PA 46 9.00E-24

97 NADH dehydrogenase, putative 83 77



acetyl-CoA acetyltransferase.

1E-061 Lipid metabolism 1E-102 CPIJ002342-PA 302 1.00E-153 87 76

96 3-ketoacyl-coa thiolase, mitochondrial (beta- ketothiolase) (acetyl-coa

C22 modification, protein turnover, chaperones

2E-048 Posttranslationalsubunit. 1E-19 CPIJ011413-PA 135 3.00E-76 98

99 peroxiredoxins, prx-1, prx-2, prx-3 53

CPIJ014120-PA 258

0.47 Translation, ribosomal structure and biogenesis 1.00E-136

96 endoU protein, putative 89 45



3E-037 3-ketoacyl-CoA thiolase.

Lipid metabolism 3E-68 CPIJ018065-PA 239 99 enzyme beta 96

trifunctional 1.00E-133 subunit (tp-beta) 51

1E-021 ATP-dependent.2E-07 CPIJ005595-PA 273

Secondary metabolites biosynthesis, transport, and catabolism 94 1.00E-121

fatty acid synthase 76 11

3E-067 transketolase.0.0004

Energy production and conversion CPIJ011779-PA 264 94 1.00E-140

pyruvate dehydrogenase 89 60

5E-013 feruloyl-CoA synthase. CPIJ010493-PA 145

Lipid metabolism 0.0004 97 5.00E-39

amp dependent ligase 89 13

CPIJ014133-PA 212 95 saposin 1.00E-106 80 21

CPIJ001670-PA 118 94 6.00E-51 81

glycerol-3-phosphate acyltransferase 13



phosphoribosylaminoimidazole-succinocarboxamide synthase. biosynthesis protein 6, pur6

2E-13 CPIJ009002-PA 267

7E-016 Nucleotide transport and metabolism 96 purine 1.00E-141 91 62

CPIJ014120-PA 258

0.47 Translation, ribosomal structure and biogenesis 1.00E-136

96 endoU protein, putative 89 45

0.29 acyl-carrier protein CPIJ001121-PA 128 1.00E-39

90 conserved hypothetical protein 62 41



2E-019 competence dynamics CPIJ014768-PA

0.23

Chromatin structure and damage-inducible protein A. 97 100 histone H4 7.00E-51 100 94

3E-016 ribosomal structure and biogenesis

0.16 CPIJ007531-PA

Translation,transcription termination factor Rho. 36 88 1.00E-58

40S ribosomal protein S10 85 80

1E-017 Function unknown CPIJ009364-PA 123 94 1.00E-56

anamorsin, putative 86 48

0.35 maltodextrin glucosidase.

Function unknown 1 CPIJ009351-PA 199 97 1.00E-108

Mob3B protein, putative 90 81



0.017 V-type ATP synthase CPIJ018056-PA 161

0.025

General function prediction only subunit I. 96 1.00E-75

clathrin light chain 83 58

3E-015 GTP-binding protein CPIJ009089-PA 147

0.001

General function prediction only Era. 99 3.00E-84

ras-related protein Rab-7 99 71

0.002 Function unknown CPIJ015616-PA 277 97 carboxypeptidase

d-alanyl-d-alanine 0.77 24 18

0.009 formate 0.59

Function unknown dehydrogenaseCPIJ015616-PA 281

accessory protein FdhE. 97 0.35

conserved hypothetical protein 20 32

0.20 trafficking and 0.24

secretion

Intracellular type II citrate synthase. CPIJ009776-PA 116 98 1.00E-60 97

clathrin coat adaptor ap3 medium chain 28

0.16 Transcription CPIJ012645-PA 90 3.00E-37 91

93 nuclear RNA export factor 2 (NXF2), putative8

CPIJ018629-PA 112

4E-005 Posttranslational modification, protein turnover, chaperones 3.00E-34 gst

90 glutathione-s-transferase theta, 59 50

DNA polymerase I.

0.056 CPIJ018234-PA 249

0.011 Inorganic ion transport and metabolism 0.4

97 zinc carboxypeptidase 32 16



3E-025 CPIJ006869-PA 266

Posttranslational modification, protein turnover, chaperones 90 serine protease8.00E-74 49 86

3E-012 molecular chaperone DnaK.

1E-16 CPIJ003550-PA 132

Posttranslational modification, protein turnover, chaperones 97 hypothetical protein0.003 29 3

5E-076 molecular chaperone DnaK.

1E-102 CPIJ003550-PA 300

Posttranslational modification, protein turnover, chaperones 99 t complex protein0.002 26 13

0.22 transport protoheme IXCPIJ000161-PA 162

0.1

Amino acid predicted and metabolism / Coenzyme metabolism

synthesis protein. 96 2.00E-82

conserved hypothetical protein 92 72

0.20 multidrug resistance CPIJ007659-PA 216

only

General function prediction0.65 outer membrane protein MdtQ. 87 1.00E-81

conserved hypothetical protein 67 79

0.17 acetyl-CoA carboxylaseCPIJ012464-PA 168

Lipid metabolism 0.12 biotin carboxylase subunit. 98 0.76

conserved hypothetical protein 50 7

6E-016 ribosomal structure and

0.002 CPIJ006022-PA 226

Translation,elongation factor 1-beta. biogenesis 95 1.00E-114

elongation factor 1-beta2 91 99

8E-006 hypothetical protein. CPIJ017344-PA 124

0.016

Posttranslational modification, protein turnover, chaperones 96 cathepsin l 5.00E-67 91 23

CPIJ007327-PA 183 95 2.00E-94 92

protein disulfide-isomerase A6 precursor 40

proline/glycine0.005 transporter.

betaine CPIJ002330-PA 107

0.002 Posttranslational modification, protein turnover, chaperones 95 1.00E-50

prefoldin, subunit, putative 88 78

translocation protein CPIJ002177-PA 202

only

1E-015 General function prediction0.23 TolB precursor. 99 1.00E-112 93 29

translation initiation factor 3, subunit S9, putative

0.097 CPIJ015372-PA

electron transport complex protein RnfG. 92 97 2.00E-47

conserved hypothetical protein 90 25

peptidyl-prolyl 2E-11 CPIJ008841-PA 161

cis-trans isomerase A (rotamase

9E-041 Posttranslational modification, protein turnover, chaperonesA). 67 cis-trans 94

peptidyl-prolyl2.00E-93 isomerase f, ppif 82

chromosome segregation protein.

0.007

0.077 General function prediction only CPIJ004013-PA 249 87 3.00E-90

slender lobes, putative 70 22

CPIJ017415-PA 184

2E-011 Cell envelope biogenesis, outer membrane 97 1.00E-97

glycosyl transferase 92 38

0.051 CPIJ018866-PA 124

ribonucleotide-diphosphate reductase subunit alpha. 97 isomerase

peptidylprolyl 5.00E-57 82 39



1E-134 proteasome-activating nucleotidase.

1E-116 CPIJ003334-PA 323

Posttranslational modification, protein turnover, chaperones 98 0

26S protease regulatory subunit98 S10b 82

4E-093 proteasome-activating nucleotidase.

2E-76 CPIJ009931-PA 267

Posttranslational modification, protein turnover, chaperones 99 1.00E-145

26S protease regulatory subunit97 66

1E-008 ribosomal structure and biogenesis

0.000005 CPIJ003099-PA 130

Translation,30S ribosomal protein S27ae. 100 3.00E-73 100

ubiquitin (ribosomal protein L40) 83

5E-035 CPIJ005007-PA 115

Posttranslational modification, protein turnover, chaperones 96 1.00E-59

E3 ubiquitin ligase 79 16

6E-012 proteasome subunit alpha.

0.033 CPIJ004203-PA 107

Posttranslational modification, protein turnover, chaperones 97 4.00E-49

proteasome subunit beta type 6,985 47



2E-014 methionyl-tRNA synthetase.

1E-24

General function prediction only CPIJ005868-PA 169 5.00E-79 84 52

95 aminoacyl-tRNA synthetase auxiliary protein, 43kD, putative

3E-039 ribosomal structure S3P.

protein CPIJ013941-PA 221

Translation,30S ribosomal1E-31 and biogenesis 1.00E-115

99 40S ribosomal protein S3 95 86

5E-053 ribosomal structure and

3E-40 CPIJ016525-PA 295

Translation,histidyl-tRNA synthetase.biogenesis 1.00E-148

96 histidyl-tRNA synthetase 87 57

3E-020 ribosomal structure L35Ae.

protein CPIJ008184-PA 104

Translation,50S ribosomal7E-11 and biogenesis 7.00E-54

99 ribosomal protein L35A, putative 94 60

9E-009 ribosomal structure L30P.

protein CPIJ010020-PA 172

Translation,50S ribosomal2E-22 and biogenesis 1.00E-94

97 60S ribosomal protein L7 94 65

2E-023 Transcription CPIJ010586-PA 91 ty

97 suppressor of1.00E-49 92 78

1E-028 ribosomal structure and biogenesis / RNA226

0.000002 CPIJ009285-PA processing and U3 small nucleolar ribonucleoprotein protein54

Translation,ribosomal biogenesis protein. 96 modification1.00E-118 88 imp4

CPIJ004543-PA 169 ribosomal S35,

92 mitochondrial6.00E-80 protein,81 putative 51

8E-013 ribosomal structure and biogenesis

0.44 CPIJ010528-PA 145

Translation,50S ribosomal protein LX. 2.00E-79

96 60S ribosomal protein L18a 96 82

2E-013 ribosomal structure S8e.

protein CPIJ011589-PA 162

Translation,30S ribosomal4E-08 and biogenesis 6.00E-82

98 40S ribosomal protein S8 91 79

0.45 CPIJ014663-PA 156

3-hydroxybutyryl-CoA dehydratase. 7.00E-86

95 elongation factor 1 gamma 89 36

1E-012 ribosomal structure and biogenesis

0.0009 CPIJ013966-PA 97

Translation,30S ribosomal protein S25e. 1.00E-49

98 ribosomal protein S25, putative 95 64

8E-012 ribosomal structure S25e.

protein CPIJ013966-PA 94

Translation,30S ribosomal0.003 and biogenesis 2.00E-47

98 ribosomal protein S25, putative 95 62

0.010 ribosomal structure L3P.

protein CPIJ007488-PA 143

Translation,50S ribosomal2E-13 and biogenesis 0

98 hypothetical protein.92 31 5

0.008 and chromosome partitioning / Transcription

0.038 KefA.

Cell divisionpotassium efflux proteinCPIJ011733-PA 267 1.00E-122

95 conserved hypothetical protein 82 21

7E-007 ribosomal structure L18P.

protein CPIJ010112-PA 227

Translation,50S ribosomal6E-19 and biogenesis 1.00E-124

98 ribosomal protein L5 95 76

0.95 and chromosome partitioning

0.66 CPIJ020266-PA

Cell divisionHolliday junction-specific endonuclease. 174 2.00E-72

93 hypothetical protein 76 66

0.019 hypothetical protein. CPIJ014785-PA 236

0.21 91 mitochondrial ribosomal protein,80 putative

DNA replication, recombination, and repair / General function prediction only 1.00E-105 L46, 88

3E-016 ribosomal structure S4.

protein CPIJ004888-PA 140

Translation,30S ribosomal2E-19 and biogenesis 1.00E-73

97 40S ribosomal protein S9 97 72

0.33 DNA modification, protein turnover, chaperones

0.0003 CPIJ015682-PA 191

Posttranslational polymerase III subunits gamma and tau. 5.00E-63

85 translation initiation factor if-2 68 20

4E-026 ribosomal structure S3P.

protein CPIJ013941-PA 165

Translation,30S ribosomal1E-21 and biogenesis 3.00E-83

99 40S ribosomal protein S3 93 64

2E-052 ribosomal structure L2P.

protein CPIJ000162-PA 199

Translation,50S ribosomal2E-59 and biogenesis 1.00E-115

100 60S ribosomal protein L8 100 76

9E-054 ribosomal structure and biogenesis

5E-58

Translation,elongation factor EF-2. CPIJ001132-PA 299 1.00E-174 97

98 eukaryotic translation elongation factor 35

0.14 transcription elongation CPIJ006763-PA protein.

Function unknown 0.36 factor NusA-like 164 98 3.00E-88

40S ribosomal protein S7 96 85

9E-038 ribosomal structure S19e.

protein CPIJ004482-PA 156

Translation,30S ribosomal5E-34 and biogenesis 100 2.00E-79

40S ribosomal protein S19 92 100

1E-037 ribosomal structure S19e.

protein CPIJ004482-PA 156

Translation,30S ribosomal6E-34 and biogenesis 98 2.00E-78

40S ribosomal protein S19 91 100

9E-010 CPIJ012933-PA 152

Translation, ribosomal structure and biogenesis 23 2.00E-51

ribosomal protein L36, putative 97 88

8E-012 CPIJ013619-PA 69

Translation, ribosomal structure and biogenesis 33 1.00E-60

ribosomal protein L36, putative 98 100

7E-013 ribosomal structure and biogenesis

0.66 CPIJ010528-PA 177

Translation,50S ribosomal protein LX. 98 1.00E-100

60S ribosomal protein L18a 98 100

1E-016 ribosomal structure L37Ae.

protein CPIJ007698-PA 89

Translation,50S ribosomal1E-14 and biogenesis 100 1.00E-47

60S ribosomal protein L37a 98 100

1E-014 ribosomal structure S27e.

protein CPIJ005652-PA 84

Translation,30S ribosomal3E-11 and biogenesis 98 0.65

conserved hypothetical protein 35 6

8E-016 V-type and synthase subunit E.

7E-10

Energy production ATPconversion CPIJ006751-PA 226 96 synthase

vacuolar atp1.00E-110subunit e89 100

6E-027 ribosomal structure L10e.

protein CPIJ018688-PA 218

Translation,50S ribosomal7E-45 and biogenesis 97 1.00E-119

60S ribosomal protein L10 91 99

CPIJ004998-PA 21 100 5.6

conserved hypothetical protein 42 4

0.078 CPIJ008169-PA 101

Inorganic ion transport and metabolism 98 0

hypothetical protein.65 48 4

6E-004 ribosomal structure and biogenesis

0.0001 CPIJ016408-PA 132

Translation,30S ribosomal protein S30e. 98 3.00E-59

40S ribosomal protein S30 84 100

5E-021 ribosomal structure S9P.

protein CPIJ008265-PA 103

Translation,30S ribosomal1E-25 and biogenesis 99 3.00E-53

ribosomal protein S9, putative 97 70

CPIJ004543-PA 174 89 ribosomal S35,

mitochondrial9.00E-80 protein,78 putative 53

9E-023 ribosomal structure S8e.

protein CPIJ011589-PA 195

Translation,30S ribosomal2E-16 and biogenesis 99 1.00E-101

40S ribosomal protein S8 92 95

3E-015 ribosomal structure L19e.

protein CPIJ014540-PA 145

Translation,50S ribosomal7E-13 and biogenesis 100 6.00E-77

60S ribosomal protein L19 95 85

1E-006 ribosomal structure L15P.

protein CPIJ015042-PA 106

Translation,50S ribosomal5E-09 and biogenesis 94 2.00E-05

hypothetical protein 52 91

1E-125 ribosomal structure CPIJ009962-PA 295

1E-136

Translation,elongation factor Tu.and biogenesis 100 1.00E-162

elongation factor tu (ef-tu) 95 63

7E-038 ribosomal structure S2.

protein CPIJ013899-PA 258

Translation,30S ribosomal1E-44 and biogenesis 93 1.00E-127 87 89

40S ribosomal protein sa (P40) (34/67 kda laminin receptor) (colon carc

large subunit. 0.25 CPIJ003335-PA 111 70 4.00E-13

conserved hypothetical protein 37 46

0.51 General function prediction only CPIJ015948-PA 185 88 3.00E-68

conserved hypothetical protein 68 14

5E-015 ribosomal structure L31e.

protein CPIJ010692-PA 106

Translation,50S ribosomal7E-11 and biogenesis 99 2.00E-56

60S ribosomal protein L31 98 85

0.38 Signal transduction mechanisms CPIJ012970-PA 113 97 8.00E-50 85 39

eukaryotic translation initiation factor 3f, eif3f

CPIJ019465-PA 90 96 2.00E-41

60S ribosomal protein L24 94 59

4E-026 ribosomal structure S3Ae.

protein CPIJ008584-PA 154

Translation,30S ribosomal7E-16 and biogenesis 98 1.00E-78

40S ribosomal protein S3a 90 57

8E-015 ribosomal 3E-14 CPIJ018118-PA 109

Translation,amidase. structure and biogenesis 97 amidase 2.00E-55 91 19

1E-010 ribosomal structure L6P.

protein CPIJ002453-PA 103

Translation,50S ribosomal2E-14 and biogenesis 95 2.00E-50

60S ribosomal protein L9 94 54



magnesium transporter.CPIJ018021-PA 317

6E-25

1E-068 Inorganic ion transport and metabolism 1.00E-177 95 32

97 calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (c

0.3

DNA polymerase III DnaE.CPIJ015433-PA 93 0.32

25 conserved hypothetical protein 26 7

2-deoxy-D-gluconate 3-dehydrogenase. 158

0.12 CPIJ004924-PA

0.007 Cell envelope biogenesis, outer membrane 1.00E-11

68 hypothetical protein 25 32

3E-016 General function prediction only CPIJ007404-PA 209 1.00E-117 97

98 guanine nucleotide-binding protein beta 3 (g61protein beta3)

transport and metabolism

0.63 CPIJ018913-PA 212

0.21 Amino acid putative aminopeptidase 2. 1.00E-119

98 conserved hypothetical protein 98 47

adenylosuccinate synthetase.

0.41 Function unknown 0.3 CPIJ002898-PA 133 3.00E-71 93 24

98 5'-AMP-activated protein kinase, catalytic alpha-1 chain

oxidoreductase. .46

0

5E-064 Signal transduction mechanisms CPIJ011522-PA 302 1.00E-163

97 suppressor of actin (sac) 90 51

3-deoxy-D-manno-octulosonic-acid kinase.253

0.036 CPIJ018269-PA Transcription / 1.00E-155

DNA replication, recombination, and repair

6E-019 General function prediction only / Signal transduction mechanisms /46 tyrosine kinase receptor 97 38



0.20 DNA polymerase III subunits gamma and tau.

Function unknown 0.0004 CPIJ014325-PA 112 3.00E-78

84 conserved hypothetical protein 73 52

4E-022 predicted transporter subunit: ATP-binding107

Transcription of transcription initiation factor TFIID subunit 12

0.88 CPIJ011778-PA component100ABC superfamily. 2.00E-57 100 59

0.082 CPIJ003641-PA 314

Amino acid transport and metabolism / Coenzyme metabolism 1.00E-140

92 conserved hypothetical protein 75 49

0.001 GTPase ObgE. 0.0002

General function prediction only CPIJ018769-PA 193 1.00E-155

25 nucleolar gtp-binding protein 90 46



0.016 NADH dehydrogenase CPIJ002845-PA 198

only

General function prediction0.32 subunit N. 9.00E-90

96 monocarboxylate transporter 95 23

0.030 General function prediction only CPIJ010030-PA 91 2.00E-47 93

96 phosphatidylethanolamine-binding protein 43

0.29 and secretion /0.24 transduction complex subunit delta.mitochondrial phosphate carrier 93

Signal CPIJ013142-PA 208

Cell motility acetyl-CoA decarbonylase/synthasemechanisms 97 1.00E-112 protein 99

0.003 V-type and synthase subunit K.

0.019

Energy production ATPconversion CPIJ004794-PA 155 9.00E-80 96

99 vacuolar atp synthase proteolipid subunit 75

0.34 CPIJ005339-PA 123

Cell envelope biogenesis, outer membrane 0.84

95 conserved hypothetical protein 33 6

0.086 Function unknown CPIJ010191-PA 116 3.00E-34

90 conserved hypothetical protein 51 5

5E-005 General function prediction only CPIJ014421-PA 99 1.00E-51 90 18

96 sodium/chloride dependent neurotransmitter transporter

0.92 short chain dehydrogenase.

0.22

Signal transduction mechanisms CPIJ004069-PA 223 97 2.00E-71 62 102

secreted ferritin G subunit precursor, putative

1E-043 magnesium transporter.CPIJ005964-PA

1E-09

Inorganic ion transport and metabolism 198 85 1.00E-171

na+/k+ atpase alpha subunit 96 30

0.22 preprotein translocase CPIJ007204-PA

only

General function prediction0.88 subunit SecF. 298 96 1.00E-142

conserved hypothetical protein 79 9

8E-025 ApaG. 3E-30 CPIJ013390-PA

Inorganic ion transport and metabolism 245 93 1.00E-126

conserved hypothetical protein 88 61

0.006 ribosomal structure and biogenesis

0.019 CPIJ001357-PA

Translation,N-acetylmuramoyl-L-alanine amidase. 301 83 1.00E-100

conserved hypothetical protein 57 15



CPIJ005317-PA 234 96 1.00E-126

conserved hypothetical protein 93 56

CPIJ005317-PA 234 94 1.00E-123

conserved hypothetical protein 90 56

0.52

DNA translocase FtsK. CPIJ009623-PA 148 79 9.00E-29

conserved hypothetical protein 82 40

0.19 phenol 0.71 CPIJ011395-PA 193

Function unknown 2-monooxygenase. 91 1.00E-72

conserved hypothetical protein 70 28

4E-12 CPIJ000363-PA 115

nicotinate phosphoribosyltransferase. 100 4.00E-47 94

nicotinate phosphoribosyltransferase 40

0.28 chromosome segregation protein.

0.06

Energy production and conversion CPIJ001685-PA 60 66 6.00E-23

conserved hypothetical protein 24 45

0.64 phosphoenolpyruvate synthase.

0.26 CPIJ001686-PA 127

Posttranslational modification, protein turnover, chaperones 81 3.00E-28

conserved hypothetical protein 43 39

ligase

lipoate-protein0.0006 A.CPIJ006031-PA 106 95 6.00E-47

conserved hypothetical protein 76 27

0.92 CPIJ005493-PA 136

DNA replication, recombination, and repair 93 6.00E-39

conserved hypothetical protein 62 59

0.17 Transcription CPIJ005493-PA 237 90 4.00E-59

conserved hypothetical protein 57 100

CPIJ011534-PA 172 80 2.00E-39

conserved hypothetical protein 57 25

0.022 Function unknown CPIJ010473-PA 109 94 1.00E-47

conserved hypothetical protein 77 32

9E-018 Function unknown CPIJ001350-PA 93 97 carboxylesterase 4.3 45 11

CPIJ000323-PA 101 99 1.00E-41

conserved hypothetical protein 83 20

3E-004 hypothetical protein. CPIJ005059-PA 163

0.002

Secondary metabolites biosynthesis, transport, and catabolism 95 3.00E-67

conserved hypothetical protein 75 81

8E-009 Function unknown CPIJ012528-PA 146 94 1.00E-71

conserved hypothetical protein 87 57

CPIJ008478-PA 75 73 1.00E-05

hypothetical protein 44 14

CPIJ017044-PA 76 85 1.9 24 5

structural maintenance of chromosomes smc4

CPIJ010352-PA 155 93 1.00E-64

conserved hypothetical protein 81 99

CPIJ017043-PA 78 93 0.66

fibrinogen and fibronectin 37 16

CPIJ007542-PA 102 90 5.00E-35

conserved hypothetical protein 66 98

amidase. 0.18 CPIJ000323-PA 41 75 5.00E-57

conserved hypothetical protein 87 24

0.97 Signal transduction mechanisms CPIJ005322-PA 142 95 2.00E-53

conserved hypothetical protein 69 104

CPIJ000323-PA 143 97 2.00E-63

conserved hypothetical protein 86 28

0.97 Carbohydrate transport and metabolismCPIJ011206-PA 64 93 6.00E-31

conserved hypothetical protein 89 63

0.38 CPIJ011711-PA 120

acetyl-CoA acetyltransferase. 88 6.00E-39

hypothetical protein 67 9

0.026 potassium efflux protein KefA.

0.019

General function prediction only CPIJ005084-PA 193 92 1.00E-87

conserved hypothetical protein 82 91

0.12

glycine dehydrogenase.CPIJ003536-PA 123 80 1.00E-24

conserved hypothetical protein 48 32

0.16 Function unknown CPIJ017599-PA 265 81 1.00E-36

conserved hypothetical protein 31 53

0.37 DNA polymerase II large subunit.

Function unknown 0.42 CPIJ010960-PA 178 92 4.00E-82

conserved hypothetical protein 83 52

CPIJ009116-PA 82 90 9.00E-32

conserved hypothetical protein 64 7

0.005 ATP-dependentonly CPIJ011422-PA 104

RNA

General function prediction0.08 helicase RhlB. 60 1.00E-07

hypothetical protein 44 16

1E-008 General function prediction only CPIJ004082-PA 143 95 rab11 2.00E-73 94 67

Clustered Clustered Clustered

at 30%- at 40%- at 50%-

Best Sim- on Sim- on Sim- on

match to Clustered 50% of 50% of 50% of

AGPROT % Match by length - - length - - length - -

database E value % identity length psiblast # seqs Cluster# # seqs Cluster# # seqs Cluster#









3.00E-42

AGAP008278-PA 35 91 2 11 3 7 4 6 4

3.00E-45

AGAP008278-PA 32 101 2 11 3 7 4 6 4

3.00E-38

AGAP008278-PA 33 84 2 11 3 7 4 6 4

1.00E-37

AGAP008278-PA 30 94 2 11 3 7 4 6 4

4.00E-36

AGAP008278-PA 29 94 2 11 3 7 4 6 4

1.00E-32

AGAP008278-PA 31 78 2 11 3 7 4 6 4

AGAP008282-PA 0.56 28 38 2 11 1 22 26 2 25

3.00E-77

AGAP006278-PA 55 82 2 11 3 7 43 1 43

1.00E-09

AGAP010648-PA 25 41 2 11 53 1 49 1 49

8.00E-45

AGAP000278-PA 80 68 2 11 177 1 190 1 193



1.00E-05

AGAP010846-PA 25 14 4 8 5 5 5 3 5

3.00E-06

AGAP002456-PA 25 10 4 8 5 5 5 3 5

2.00E-06

AGAP002456-PA 25 10 4 8 5 5 5 3 5

AGAP005300-PC0.004 37 10 4 8 8 3 6 3 6

AGAP005300-PC0.002 37 10 4 8 8 3 6 3 6

AGAP005300-PC0.003 37 10 4 8 8 3 6 3 6

5.00E-07

AGAP009974-PA 32 70 4 8 5 5 29 2 27

2.00E-08

AGAP002737-PA 26 3 4 8 5 5 29 2 27



4.00E-14

AGAP004325-PA 48 24 23 2 26 2 19 2 71

9.00E-15

AGAP005162-PB 41 10 23 2 26 2 19 2 172

6.00E-78

AGAP009473-PA 59 90 78 1 78 1 78 1 79

AGAP007269-PA 0.71 32 9 176 1 185 1 198 1 203





AGAP002102-PA 0 59 95 3 9 4 6 3 6 3

5.00E-87

AGAP002102-PA 50 55 3 9 4 6 3 6 3

6.00E-57

AGAP002318-PA 65 29 3 9 99 1 99 1 100

1.00E-113

AGAP006371-PA 64 64 3 9 36 2 167 1 169

3.00E-94

AGAP002317-PA 72 43 3 9 36 2 220 1 227



5.00E-91

AGAP011046-PA 65 55 161 1 166 1 179 1 182



4.00E-43

AGAP010596-PA 68 20 52 1 52 1 48 1 48



6.00E-36

AGAP000240-PA 66 23 88 1 89 1 89 1 90

1.00E-114

AGAP011787-PA 64 71 5 7 6 3 21 2 20

6.00E-11

AGAP007141-PA 30 60 5 7 80 1 80 1 81

6.00E-32

AGAP001707-PA 61 17 5 7 7 3 138 1 139

2.00E-19

AGAP003252-PA 44 27 5 7 7 3 27 2 148

3.00E-38

AGAP004552-PA 65 33 5 7 7 3 27 2 198



4.00E-42

AGAP007347-PA 54 96 134 1 135 1 143 1 144

7.00E-15

AGAP005332-PC 47 58 41 1 42 1 34 1 33

3.00E-87

AGAP002798-PA 50 76 69 1 69 1 69 1 69









6.00E-29

AGAP006421-PA 39 63 13 2 16 2 41 1 41

9.00E-38

AGAP006421-PA 52 50 13 2 16 2 172 1 175





2.00E-29

AGAP011460-PA 50 105 25 2 28 2 22 2 21

2.00E-29

AGAP011460-PA 50 105 25 2 28 2 22 2 21





AGAP008187-PA0.099 27 18 34 2 179 1 192 1 195





5.00E-24

AGAP008782-PA 30 93 1 22 33 2 24 2 23



3.00E-05

AGAP001989-PA 21 74 195 1 204 1 218 1 225





AGAP006228-PA 1.2 27 15 6 6 2 7 2 6 2

AGAP005096-PA 1.1 34 5 6 6 2 7 2 6 2

AGAP008146-PA 1.9 18 44 6 6 2 7 2 6 2

AGAP010261-PA 1.4 36 4 6 6 2 7 2 6 2

AGAP010261-PA 1.5 36 4 6 6 2 7 2 6 2

AGAP010261-PA 1.1 36 4 6 6 2 7 2 6 2



AGAP004367-PA0.036 24 3 194 1 203 1 217 1 224



AGAP009841-PA 2.7 40 11 12 2 15 2 12 2 12

AGAP003808-PA 3.5 40 13 12 2 15 2 12 2 12

AGAP010175-PA 3.5 36 4 56 1 57 1 53 1 53





AGAP004833-PA 0.21 33 6 1 22 1 22 1 20 1

AGAP004833-PA 0.21 33 6 1 22 1 22 1 20 1

AGAP008782-PA 0.59 34 16 1 22 1 22 1 20 34

AGAP001415-PA 0.56 21 13 1 22 1 22 1 20 1

AGAP010599-PA 0.81 24 11 1 22 1 22 1 20 228

AGAP003702-PA 4.7 32 4 1 22 1 22 1 20 30

AGAP004870-PA 3.5 23 6 1 22 1 22 1 20 1

AGAP007503-PA 7.6 34 2 1 22 1 22 1 20 30

AGAP002200-PA 0.14 26 8 1 22 1 22 1 20 1

AGAP006838-PA 1.5 27 45 1 22 1 22 1 20 1

AGAP009037-PA 0.89 27 11 1 22 1 22 1 20 1

AGAP006838-PA 1.5 27 45 1 22 1 22 1 20 1

AGAP002655-PA 2 29 5 1 22 1 22 1 20 1

AGAP001680-PA 1.5 30 26 1 22 1 22 1 20 1

AGAP011271-PA 0.26 21 9 1 22 1 22 1 20 213

AGAP003228-PA 1.6 37 9 1 22 1 22 1 20 1

AGAP009037-PA 0.77 28 8 1 22 1 22 1 20 1

AGAP000824-PA 0.11 40 10 1 22 1 22 1 20 32

AGAP000685-PA 2 30 4 1 22 1 22 1 20 1

AGAP009037-PA 0.83 28 8 1 22 1 22 1 20 1



AGAP006268-PA 0.54 37 37 16 2 19 2 15 2 15

AGAP009790-PA 0.92 35 9 94 1 95 1 95 1 96



6.00E-08

AGAP006504-PA 35 83 118 1 118 1 123 1 124

1.00E-09

AGAP006108-PA 43 22 27 2 30 2 23 2 22

4.00E-11

AGAP007349-PA 37 7 27 2 30 2 23 2 22





1.00E-125

AGAP000651-PA 99 59 10 2 13 2 10 2 10

1.00E-174

AGAP000651-PA 99 80 10 2 13 2 10 2 10

2.00E-78

AGAP006037-PA 67 60 59 1 60 1 57 1 57

7.00E-25

AGAP000003-PA 47 39 66 1 66 1 66 1 66

8.00E-90

AGAP009210-PA 85 11 155 1 160 1 173 1 176

7.00E-59

AGAP001229-PA 98 95 166 1 171 1 184 1 187



1.00E-21

AGAP009669-PA 30 47 17 2 20 2 16 2 16

1.00E-19

AGAP009669-PA 30 42 17 2 20 2 16 2 16

4.00E-12

AGAP005721-PA 21 52 76 1 76 1 76 1 77

1.00E-16

AGAP006904-PC 36 21 131 1 132 1 140 1 141

3.00E-29

AGAP010821-PA 44 48 139 1 139 1 149 1 151

3.00E-61

AGAP003721-PA 87 41 140 1 140 1 150 1 152



7.00E-06

AGAP006483-PA 35 16 126 1 126 1 131 1 132



1.00E-43

AGAP009433-PA 59 49 11 2 14 2 11 2 11

1.00E-26

AGAP003695-PA 32 10 18 2 131 1 136 1 137

1.00E-70

AGAP005873-PA 94 100 109 1 111 1 114 1 115

1.00E-40

AGAP005053-PA 64 17 133 1 134 1 142 1 143

AGAP004373-PA 2.1 40 10 149 1 153 1 163 1 165

4.00E-55

AGAP007619-PA 94 22 150 1 154 1 164 1 166

5.00E-72

AGAP003571-PA 85 32 168 1 173 1 186 1 189

1.00E-138

AGAP001124-PA 81 70 183 1 192 1 205 1 210

5.00E-22

AGAP012008-PA 54 35 188 1 197 1 211 1 217



1.00E-174

AGAP010428-PA 86 47 83 1 84 1 84 1 85

1.00E-85

AGAP003099-PA 69 79 98 1 100 1 100 1 101

2.00E-93

AGAP002914-PA 69 58 110 1 32 2 115 1 116

7.00E-73

AGAP010866-PA 72 71 138 1 138 1 147 1 149

4.00E-92

AGAP008401-PA 54 28 178 1 187 1 200 1 205

3.00E-83

AGAP001257-PA 97 30 181 1 190 1 203 1 208

4.00E-49

AGAP009623-PA 92 30 187 1 196 1 210 1 216

3.00E-63

AGAP009571-PA 61 19 190 1 199 1 213 1 220



1.00E-120

AGAP001903-PA 91 70 91 1 92 1 92 1 93

2.00E-50

AGAP009602-PA 83 63 62 1 21 2 60 1 60

2.00E-32

AGAP007784-PA 32 34 107 1 109 1 112 1 113

AGAP002737-PA0.018 25 2 115 1 23 2 120 1 121

1.00E-83

AGAP012081-PA 95 74 148 1 152 1 162 1 164

1.00E-113

AGAP006099-PA 72 64 31 2 35 2 139 1 140

3.00E-80

AGAP001138-PA 87 69 30 2 34 2 25 2 24

2.00E-36

AGAP000184-PA 75 15 123 1 123 1 128 1 129

1.00E-156

AGAP000184-PA 85 53 165 1 170 1 183 1 186

4.00E-59

AGAP012515-PA 91 100 96 1 97 1 97 1 98

6.00E-31

AGAP002630-PA 85 69 68 1 68 1 68 1 68

7.00E-68

AGAP001138-PA 88 59 30 2 34 2 25 2 24

5.00E-65

AGAP000261-PA 58 41 130 1 130 1 135 1 136

1.00E-104

AGAP007966-PA 85 73 157 1 162 1 175 1 178

3.00E-63

AGAP007208-PA 72 89 116 1 116 1 121 1 122

1.00E-129

AGAP003768-PA 94 88 185 1 194 1 207 1 212

2.00E-68

AGAP002919-PB 54 71 75 1 75 1 75 1 76

6.00E-58

AGAP011208-PA 93 46 38 2 182 1 195 1 200

4.00E-72

AGAP006099-PA 69 43 31 2 35 2 223 1 231

1.00E-81

AGAP012048-PA 97 31 95 1 96 1 96 1 97

1.00E-176

AGAP010156-PA 93 29 145 1 146 1 156 1 158

2.00E-24

AGAP006630-PA 85 77 193 1 202 1 216 1 223



1.00E-150

AGAP006821-PA 86 76 36 2 38 2 30 2 219

8.00E-76

AGAP007543-PA 97 52 154 1 159 1 171 1 174

1.00E-121

AGAP002925-PA 78 49 114 1 115 1 119 1 120



1.00E-118

AGAP011827-PA 86 63 36 2 38 2 30 2 196

1.00E-112

AGAP009176-PA 72 11 77 1 77 1 77 1 78

1.00E-129

AGAP003136-PA 82 63 160 1 165 1 178 1 181

6.00E-62

AGAP008596-PA 74 24 163 1 168 1 181 1 184

1.00E-42

AGAP001082-PA 50 16 170 1 175 1 188 1 191

4.00E-42

AGAP003687-PA 67 13 186 1 195 1 208 1 214



1.00E-126

AGAP000180-PA 82 62 127 1 127 1 132 1 133

1.00E-121

AGAP002925-PA 78 49 114 1 115 1 119 1 120

7.00E-31

AGAP009433-PA 54 40 11 2 14 2 11 2 11



6.00E-51

AGAP003909-PA 100 94 32 2 184 1 197 1 202

2.00E-49

AGAP000739-PA 77 78 135 1 136 1 144 1 145

9.00E-52

AGAP008883-PA 77 48 142 1 143 1 153 1 155

1.00E-106

AGAP007872-PA 86 90 174 1 181 1 194 1 199



2.00E-64

AGAP010608-PA 92 57 117 1 117 1 122 1 123

5.00E-73

AGAP001617-PA 95 68 19 2 22 2 137 1 138

1.00E-129

AGAP006625-PA 80 90 22 2 25 2 18 2 18

1.00E-131

AGAP006625-PA 80 91 22 2 25 2 18 2 18

1.00E-48

AGAP001484-PA 77 28 84 1 85 1 85 1 86

2.00E-18

AGAP002004-PA 75 6 162 1 167 1 180 1 183

8.00E-32

AGAP009195-PA 54 49 164 1 169 1 182 1 185

1.00E-110

AGAP001721-PA 80 87 177 1 186 1 199 1 204



6.00E-59

AGAP003252-PA 40 74 5 7 6 3 44 1 44

1.00E-64

AGAP004192-PA 89 20 28 2 106 1 108 1 109

1.00E-162

AGAP004192-PA 95 46 28 2 141 1 151 1 153

7.00E-74

AGAP005801-PA 86 66 64 1 64 1 62 1 62

4.00E-09

AGAP003304-PA 71 40 71 1 71 1 71 1 72

AGAP001827-PA 3.1 38 4 73 1 73 1 73 1 74

1.00E-104

AGAP010613-PA 85 100 74 1 74 1 74 1 75

4.00E-64

AGAP012900-PA 86 92 80 1 81 1 81 1 82

4.00E-85

AGAP001919-PA 79 41 85 1 86 1 86 1 87

3.00E-43

AGAP006946-PA 73 78 86 1 87 1 87 1 88

1.00E-106

AGAP012140-PA 88 30 122 1 122 1 127 1 128

3.00E-47

AGAP002626-PA 87 25 129 1 129 1 134 1 135

3.00E-86

AGAP000462-PA 86 95 146 1 147 1 157 1 159

2.00E-62

AGAP003457-PA 69 18 152 1 157 1 168 1 170

2.00E-88

AGAP011324-PA 86 38 158 1 163 1 176 1 179

6.00E-46

AGAP000725-PA 73 38 196 1 205 1 219 1 226



AGAP001407-PA 0 98 81 29 2 31 2 110 1 111

1.00E-143

AGAP007243-PA 97 65 29 2 31 2 148 1 150

3.00E-23

AGAP002599-PA 100 22 48 1 48 1 42 1 42

1.00E-56

AGAP011242-PA 73 16 92 1 93 1 93 1 94

1.00E-49

AGAP009271-PA 84 47 167 1 172 1 185 1 188



2.00E-80

AGAP010586-PA 85 51 37 2 39 2 31 2 28

1.00E-109

AGAP001910-PA 97 82 40 2 41 2 33 2 31

1.00E-131

AGAP000735-PA 79 53 81 1 82 1 82 1 83

3.00E-50

AGAP002754-PA 86 56 172 1 178 1 191 1 194

1.00E-87

AGAP008916-PA 89 65 202 1 212 1 228 1 236

8.00E-48

AGAP005428-PA 90 78 65 1 65 1 63 1 63

1.00E-104

AGAP009968-PA 76 95 175 1 183 1 196 1 201

1.00E-68

AGAP006802-PA 70 50 21 2 24 2 17 2 17

3.00E-77

AGAP012284-PA 92 82 35 2 37 2 28 2 26

8.00E-65

AGAP002437-PA 89 99 39 2 40 2 32 2 29

3.00E-83

AGAP000883-PA 87 37 103 1 104 1 105 1 106

1.00E-47

AGAP004462-PA 93 63 7 2 9 2 7 2 7

2.00E-46

AGAP004462-PA 94 61 7 2 9 2 7 2 7

5.00E-74

AGAP003556-PA 93 33 108 1 110 1 113 1 114

6.00E-59

AGAP007808-PA 52 22 156 1 161 1 174 1 177

4.00E-94

AGAP009031-PA 90 56 173 1 180 1 193 1 197

2.00E-64

AGAP002012-PA 75 59 184 1 193 1 206 1 211

5.00E-96

AGAP006684-PA 73 88 20 2 32 2 209 1 215

1.00E-73

AGAP005061-PB 96 72 42 1 43 1 35 1 35

4.00E-25

AGAP004824-PA 55 12 63 1 63 1 61 1 61

3.00E-78

AGAP001910-PA 97 59 40 2 41 2 33 2 31

1.00E-114

AGAP005802-PA 97 76 44 1 45 1 37 1 37

1.00E-171

AGAP009441-PA 95 35 147 1 148 1 158 1 160

5.00E-86

AGAP010592-PA 94 85 197 1 206 1 221 1 229

3.00E-73

AGAP010933-PA 83 97 9 2 11 2 9 2 9

5.00E-73

AGAP010933-PA 83 97 9 2 11 2 9 2 9

2.00E-51

AGAP002921-PA 98 86 14 2 17 2 13 2 13

3.00E-60

AGAP002921-PA 98 98 14 2 17 2 13 2 13

3.00E-96

AGAP012284-PA 93 100 35 2 37 2 28 2 26

3.00E-47

AGAP009920-PA 97 100 49 1 49 1 45 1 45

2.00E-46

AGAP007157-PA 95 100 54 1 55 1 51 1 51

1.00E-106

AGAP002401-PA 84 100 97 1 98 1 98 1 99

1.00E-120

AGAP002395-PA 91 100 143 1 144 1 154 1 156

1.00E-08

AGAP007087-PA 100 100 189 1 198 1 212 1 218

AGAP003817-PA 2.6 38 4 191 1 200 1 214 1 221

3.00E-48

AGAP000654-PA 74 100 203 1 213 1 229 1 237

5.00E-53

AGAP011424-PA 97 70 20 2 23 2 65 1 65

5.00E-70

AGAP006802-PA 69 51 21 2 24 2 17 2 17

1.00E-64

AGAP002437-PA 89 99 39 2 40 2 32 2 29

3.00E-76

AGAP004422-PA 95 76 55 1 56 1 52 1 52

1.00E-42

AGAP011706-PA 74 72 136 1 137 1 145 1 146

1.00E-162

AGAP006996-PA 95 63 169 1 174 1 187 1 190

1.00E-105

AGAP011777-PA 74 90 51 1 51 1 47 1 47

AGAP001363-PA 0.54 28 11 182 1 191 1 204 1 209

1.00E-64

AGAP006517-PA 68 11 199 1 208 1 224 1 232

6.00E-56

AGAP011896-PA 95 85 61 1 62 1 59 1 59

2.00E-48

AGAP002935-PA 84 39 144 1 145 1 155 1 157

6.00E-35

AGAP010216-PA 82 59 99 1 101 1 101 1 102

3.00E-69

AGAP003532-PA 83 57 38 2 210 1 226 1 234

3.00E-51

AGAP011315-PA 82 20 128 1 128 1 133 1 134

4.00E-50

AGAP009508-PA 94 54 179 1 188 1 201 1 206



1.00E-171

AGAP006186-PD 91 31 26 2 29 2 170 1 173

AGAP012234-PA 1 26 74 47 1 47 1 40 1 40

2.00E-05

AGAP004877-PA 24 14 57 1 58 1 54 1 54

1.00E-113

AGAP005913-PA 94 61 67 1 67 1 67 1 67

1.00E-118

AGAP011252-PA 96 49 119 1 119 1 124 1 125

2.00E-67

AGAP002686-PA 89 25 137 1 21 2 146 1 147

1.00E-112

AGAP000891-PA 64 52 141 1 142 1 152 1 154

1.00E-154

AGAP011648-PA 97 38 151 1 155 1 165 1 167



3.00E-39

AGAP003356-PA 46 53 72 1 72 1 72 1 73

1.00E-56

AGAP003135-PA 98 61 32 2 149 1 159 1 161

1.00E-117

AGAP005299-PA 64 62 93 1 94 1 94 1 95

1.00E-141

AGAP007050-PA 81 46 100 1 102 1 102 1 103



1.00E-88

AGAP003206-PA 93 23 112 1 113 1 117 1 118

2.00E-44

AGAP008909-PA 86 44 121 1 121 1 126 1 127

1.00E-109

AGAP003586-PA 90 56 70 1 70 1 70 1 70

2.00E-79

AGAP009334-PA 96 73 90 1 91 1 91 1 92

AGAP002529-PA 0.71 30 6 60 1 61 1 58 1 58

4.00E-28

AGAP004203-PB 47 5 33 2 150 1 160 1 162

8.00E-53

AGAP009768-PA 92 16 102 1 103 1 104 1 105

2.00E-48

AGAP002464-PA 47 95 45 1 46 1 38 1 38

1.00E-166

AGAP002858-PA 93 30 26 2 29 2 106 1 107

1.00E-102

AGAP001826-PA 60 9 105 1 107 1 109 1 110

1.00E-125

AGAP001153-PA 85 62 159 1 164 1 177 1 180

2.00E-90

AGAP004203-PB 51 15 33 2 151 1 161 1 163



1.00E-124

AGAP010020-PA 91 56 24 2 27 2 20 2 19

1.00E-122

AGAP010020-PA 88 56 24 2 27 2 20 2 19

4.00E-19

AGAP004150-PA 60 58 113 1 114 1 118 1 119

2.00E-38

AGAP006092-PA 41 28 132 1 133 1 141 1 142

2.00E-58

AGAP008516-PA 89 22 125 1 125 1 130 1 131

2.00E-05

AGAP002737-PA 26 4 18 2 2 7 55 1 55

2.00E-11

AGAP004334-PA 25 38 50 1 50 1 46 1 46

2.00E-41

AGAP012186-PA 71 26 106 1 108 1 111 1 112

3.00E-16

AGAP003612-PA 33 61 8 2 10 2 8 2 8

1.00E-32

AGAP003612-PA 37 98 8 2 10 2 8 2 8

AGAP008698-PA0.007 26 5 198 1 207 1 222 1 230

1.00E-45

AGAP012271-PA 72 33 180 1 189 1 202 1 207

2.00E-43

AGAP003239-PA 84 35 53 1 54 1 50 1 50

2.00E-31

AGAP006063-PA 58 21 15 2 18 2 14 2 14

4.00E-73

AGAP002320-PA 82 81 87 1 88 1 88 1 89

3.00E-63

AGAP009288-PA 77 57 111 1 112 1 116 1 117

AGAP007368-PA0.007 47 3 16 2 19 2 15 2 15

AGAP002004-PA 2.1 27 6 46 1 12 2 39 1 39

2.00E-57

AGAP012587-PA 71 93 58 1 59 1 56 1 56

AGAP004322-PA 0.92 31 7 101 1 12 2 103 1 104

1.00E-26

AGAP005620-PA 73 65 104 1 105 1 107 1 108

5.00E-56

AGAP006063-PA 84 21 153 1 158 1 169 1 171

8.00E-37

AGAP002328-PA 52 101 201 1 211 1 227 1 235

2.00E-43

AGAP006063-PA 55 28 15 2 18 2 14 2 14

AGAP011102-PA 0.54 30 45 200 1 209 1 225 1 233

4.00E-26

AGAP001467-PA 53 11 82 1 83 1 83 1 84

1.00E-64

AGAP004110-PA 74 92 120 1 120 1 125 1 126

1.00E-04

AGAP009110-PA 26 31 124 1 124 1 129 1 130

1.00E-17

AGAP007453-PA 24 61 89 1 90 1 90 1 91

1.00E-67

AGAP009156-PA 70 55 171 1 176 1 189 1 192

3.00E-32

AGAP009762-PA 78 5 192 1 201 1 215 1 222

7.00E-09

AGAP007180-PA 28 7 79 1 79 1 79 1 80

2.00E-46

AGAP004559-PA 92 54 19 2 22 2 64 1 64

Clustered Clustered Clustered Clustered Clustered

at 60%- at 70%- at 80%- at 90%- at 95%-

Sim- on Sim- on Sim- on Sim- on Sim- on

50% of 50% of 50% of 50% of 50% of

length - - length - - length - - length - - length - -

# seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs









6 5 3 5 3 5 3 15 2 144 1

6 5 3 5 3 5 3 147 1 150 1

6 5 3 5 3 5 3 15 2 156 1

6 6 3 6 3 6 3 16 2 13 2

6 6 3 6 3 6 3 16 2 13 2

6 6 3 6 3 6 3 175 1 179 1

2 23 2 155 1 155 1 160 1 164 1

1 47 1 46 1 45 1 43 1 41 1

1 55 1 56 1 55 1 54 1 52 1

1 201 1 205 1 206 1 214 1 218 1



3 4 3 4 3 4 3 3 3 20 1

3 4 3 4 3 4 3 3 3 5 2

3 4 3 4 3 4 3 3 3 5 2

3 7 3 7 3 7 3 5 3 3 3

3 7 3 7 3 7 3 5 3 3 3

3 7 3 7 3 7 3 5 3 3 3

2 26 2 21 2 21 2 18 2 221 1

2 26 2 21 2 21 2 18 2 226 1



1 77 1 80 1 79 1 80 1 80 1

1 179 1 183 1 183 1 189 1 193 1

1 85 1 88 1 87 1 88 1 88 1

1 211 1 215 1 216 1 224 1 230 1





6 2 6 2 6 2 5 4 3 10 2

6 2 6 2 6 98 1 99 1 100 1

1 106 1 109 1 109 1 110 1 111 1

1 176 1 180 1 180 1 186 1 190 1

1 235 1 241 1 242 1 253 1 260 1



1 189 1 193 1 194 1 201 1 205 1



1 54 1 55 1 54 1 53 1 51 1



1 96 1 99 1 99 1 100 1 101 1

2 19 2 15 2 15 2 13 2 90 1

1 87 1 90 1 89 1 90 1 91 1

1 146 1 149 1 149 1 154 1 158 1

1 155 1 159 1 159 1 164 1 168 1

1 206 1 210 1 211 1 219 1 224 1



1 151 1 154 1 154 1 159 1 163 1

1 31 1 26 1 25 1 21 1 17 1

1 75 1 78 1 77 1 78 1 78 1









1 45 1 42 1 41 1 39 1 36 1

1 182 1 186 1 186 1 192 1 196 1





2 20 2 16 2 16 2 14 2 12 2

2 20 2 16 2 16 2 14 2 12 2





1 203 1 207 1 208 1 216 1 220 1





2 138 1 141 1 141 1 144 1 147 1



1 233 1 239 1 240 1 251 1 258 1





6 41 1 36 1 35 1 31 1 28 1

6 3 5 3 5 3 4 2 4 1 4

6 3 5 3 5 3 4 2 4 1 4

6 3 5 3 5 3 4 2 4 1 4

6 3 5 3 5 3 4 2 4 1 4

6 3 5 3 5 193 1 199 1 203 1



1 232 1 237 1 238 1 249 1 256 1



2 12 2 11 2 11 2 9 2 8 2

2 12 2 11 2 11 2 9 2 8 2

1 59 1 60 1 59 1 58 1 56 1





14 24 2 19 2 19 2 17 2 14 2

14 24 2 19 2 19 2 17 2 14 2

1 32 1 27 1 26 1 22 1 18 1

14 44 1 41 1 40 1 38 1 35 1

1 236 1 242 1 243 1 254 1 261 1

2 246 1 252 1 253 1 264 1 271 1

14 38 1 33 1 32 1 28 1 25 1

2 245 1 251 1 252 1 263 1 270 1

14 49 1 48 1 47 1 46 1 44 1

14 1 8 1 7 1 7 1 4 2 3

14 1 8 1 7 1 7 1 4 2 3

14 1 8 1 7 1 7 1 4 2 3

14 1 8 1 7 1 7 6 2 4 2

14 1 8 1 7 1 7 6 2 4 2

1 221 1 225 1 226 1 235 1 241 1

14 1 8 233 1 234 1 243 1 249 1

14 1 8 1 7 1 7 45 1 43 1

1 30 1 25 1 24 1 20 1 16 1

14 35 1 30 1 29 1 25 1 22 1

14 1 8 1 7 1 7 1 4 40 1



2 200 1 204 1 205 1 213 1 217 1

1 102 1 105 1 105 1 106 1 107 1



1 130 1 133 1 133 1 136 1 138 1

2 21 2 17 2 17 2 119 1 120 1

2 21 2 17 2 17 2 126 1 128 1





2 10 2 38 1 37 1 33 1 30 1

2 10 2 39 1 38 1 34 1 31 1

1 63 1 66 1 65 1 65 1 63 1

1 72 1 75 1 74 1 75 1 74 1

1 183 1 187 1 187 1 193 1 197 1

1 194 1 198 1 199 1 207 1 211 1



2 15 2 62 1 61 1 61 1 59 1

2 15 2 61 1 60 1 60 1 58 1

1 83 1 86 1 85 1 86 1 86 1

1 148 1 151 1 151 1 156 1 160 1

1 158 1 162 1 162 1 167 1 171 1

1 159 1 163 1 163 1 168 1 172 1



1 139 1 142 1 142 1 145 1 148 1



2 11 2 10 2 10 2 37 1 34 1

1 144 1 147 1 147 1 151 1 154 1

1 121 1 124 1 124 1 127 1 129 1

1 150 1 153 1 153 1 158 1 162 1

1 172 1 176 1 176 1 182 1 186 1

1 173 1 177 1 177 1 183 1 187 1

1 196 1 200 1 201 1 209 1 213 1

1 218 1 222 1 223 1 232 1 238 1

1 225 1 229 1 230 1 239 1 245 1



1 91 1 94 1 93 1 94 1 95 1

1 107 1 110 1 110 1 111 1 112 1

1 122 1 125 1 125 1 128 1 130 1

1 156 1 160 1 160 1 165 1 169 1

1 213 1 217 1 218 1 227 1 233 1

1 216 1 220 1 221 1 230 1 236 1

1 224 1 228 1 229 1 238 1 244 1

1 228 1 232 1 233 1 242 1 248 1



1 99 1 102 1 102 1 103 1 104 1

1 66 1 69 1 68 1 69 1 67 1

1 119 1 122 1 122 1 124 1 125 1

1 127 1 130 1 130 1 133 1 135 1

1 171 1 175 1 175 1 181 1 185 1

1 147 1 150 1 150 1 155 1 159 1

2 22 2 18 2 18 2 153 1 157 1

1 135 1 138 1 138 1 141 1 143 1

1 193 1 197 1 198 1 206 1 210 1

1 104 1 107 1 107 1 108 1 109 1

1 74 1 77 1 76 1 77 1 77 1

2 22 2 18 2 18 2 200 1 204 1

1 143 1 146 1 146 1 150 1 153 1

1 185 1 189 1 189 1 195 1 199 1

1 128 1 131 1 131 1 134 1 136 1

1 220 1 224 1 225 1 234 1 240 1

1 82 1 85 1 84 1 85 1 85 1

1 208 1 212 1 213 1 221 1 227 1

1 239 1 245 1 246 1 257 1 264 1

1 103 1 106 1 106 1 107 1 108 1

1 165 1 169 1 169 1 174 1 178 1

1 231 1 236 1 237 1 248 1 254 1



1 227 1 231 1 232 1 241 1 247 1

1 181 1 185 1 185 1 191 1 195 1

1 126 1 129 1 129 1 132 1 134 1



1 204 1 208 1 209 1 217 1 222 1

1 84 1 87 1 86 1 87 1 87 1

1 188 1 192 1 192 1 198 1 202 1

1 191 1 195 1 196 1 203 1 207 1

1 198 1 202 1 203 1 211 1 215 1

1 222 1 226 1 227 1 236 1 242 1



1 140 1 143 1 143 1 146 1 149 1

1 126 1 129 1 129 1 132 1 134 1

2 11 2 10 2 10 2 36 1 33 1



1 210 1 214 1 215 1 223 1 229 1

1 152 1 156 1 156 1 161 1 165 1

1 162 1 166 1 166 1 171 1 175 1

1 207 1 211 1 212 1 220 1 225 1



1 129 1 132 1 132 1 135 1 137 1

1 145 1 148 1 148 1 152 1 155 1

2 17 2 13 2 13 2 11 2 9 2

2 17 2 13 2 13 2 11 2 9 2

1 92 1 95 1 94 1 95 1 96 1

1 190 1 194 1 195 1 202 1 206 1

1 192 1 196 1 197 1 204 1 208 1

1 212 1 216 1 217 1 226 1 232 1



1 48 1 47 1 46 1 44 1 42 1

1 115 1 118 1 118 1 120 1 121 1

1 160 1 164 1 164 1 169 1 173 1

1 68 1 71 1 70 1 71 1 69 1

1 78 1 81 1 80 1 81 1 81 1

1 80 1 83 1 82 1 83 1 83 1

1 81 1 84 1 83 1 84 1 84 1

1 88 1 91 1 90 1 91 1 92 1

1 93 1 96 1 95 1 96 1 97 1

1 94 1 97 1 96 1 97 1 98 1

1 134 1 137 1 137 1 140 1 142 1

1 142 1 145 1 145 1 149 1 152 1

1 166 1 170 1 170 1 176 1 180 1

1 177 1 181 1 181 1 187 1 191 1

1 186 1 190 1 190 1 196 1 200 1

1 234 1 240 1 241 1 252 1 259 1



1 117 1 120 1 120 1 122 1 123 1

1 157 1 161 1 161 1 166 1 170 1

1 46 1 45 1 44 1 42 1 39 1

1 100 1 103 1 103 1 104 1 105 1

1 195 1 199 1 200 1 208 1 212 1



2 27 2 22 2 22 2 19 2 15 2

2 29 2 24 2 255 1 266 1 273 1

1 89 1 92 1 91 1 92 1 93 1

1 202 1 206 1 207 1 215 1 219 1

1 244 1 250 1 251 1 262 1 269 1

1 69 1 72 1 71 1 72 1 71 1

1 209 1 213 1 214 1 222 1 228 1

2 16 2 12 2 12 2 10 2 126 1

2 25 2 20 2 20 2 225 1 231 1

2 28 2 23 2 23 2 245 1 251 1

1 112 1 115 1 115 1 116 1 117 1

2 8 2 8 2 8 2 7 2 6 2

2 8 2 8 2 8 2 7 2 6 2

1 120 1 123 1 123 1 125 1 127 1

1 184 1 188 1 188 1 194 1 198 1

1 205 1 209 1 210 1 218 1 223 1

1 219 1 223 1 224 1 233 1 239 1

1 223 1 227 1 228 1 237 1 243 1

1 33 1 28 1 27 1 23 1 19 1

1 67 1 70 1 69 1 70 1 68 1

2 29 2 24 2 254 1 265 1 272 1

1 39 1 34 1 33 1 29 1 26 1

1 167 1 171 1 171 1 177 1 181 1

1 237 1 243 1 244 1 255 1 262 1

2 9 2 9 2 9 2 8 2 7 2

2 9 2 9 2 9 2 8 2 7 2

2 13 2 43 1 42 1 40 1 37 1

2 13 2 44 1 43 1 41 1 38 1

2 25 2 20 2 20 2 205 1 209 1

1 50 1 51 1 50 1 49 1 47 1

1 57 1 58 1 57 1 56 1 54 1

1 105 1 108 1 108 1 109 1 110 1

1 163 1 167 1 167 1 172 1 176 1

1 226 1 230 1 231 1 240 1 246 1

1 229 1 234 1 235 1 244 1 250 1

1 247 1 253 1 256 1 267 1 274 1

1 71 1 74 1 73 1 74 1 73 1

2 16 2 12 2 12 2 10 2 75 1

2 28 2 23 2 23 2 246 1 252 1

1 58 1 59 1 58 1 57 1 55 1

1 153 1 157 1 157 1 162 1 166 1

1 197 1 201 1 202 1 210 1 214 1

1 53 1 54 1 53 1 52 1 50 1

1 217 1 221 1 222 1 231 1 237 1

1 240 1 246 1 247 1 258 1 265 1

1 65 1 68 1 67 1 68 1 66 1

1 164 1 168 1 168 1 173 1 177 1

1 108 1 111 1 111 1 112 1 113 1

1 242 1 248 1 249 1 260 1 267 1

1 141 1 144 1 144 1 148 1 151 1

1 214 1 218 1 219 1 228 1 234 1



1 180 1 184 1 184 1 190 1 194 1

1 43 1 40 1 39 1 35 1 32 1

1 60 1 63 1 62 1 62 1 60 1

1 73 1 76 1 75 1 76 1 76 1

1 131 1 134 1 134 1 137 1 139 1

1 154 1 158 1 158 1 163 1 167 1

1 161 1 165 1 165 1 170 1 174 1

1 174 1 178 1 178 1 184 1 188 1



1 79 1 82 1 81 1 82 1 82 1

1 168 1 172 1 172 1 178 1 182 1

1 101 1 104 1 104 1 105 1 106 1

1 109 1 112 1 112 1 113 1 114 1



1 124 1 127 1 127 1 130 1 132 1

1 133 1 136 1 136 1 139 1 141 1

1 76 1 79 1 78 1 79 1 79 1

1 98 1 101 1 101 1 102 1 103 1

1 64 1 67 1 66 1 67 1 65 1

1 169 1 173 1 173 1 179 1 183 1

1 111 1 114 1 114 1 115 1 116 1

1 40 1 35 1 34 1 30 1 27 1

1 113 1 116 1 116 1 117 1 118 1

1 116 1 119 1 119 1 121 1 122 1

1 187 1 191 1 191 1 197 1 201 1

1 170 1 174 1 174 1 180 1 184 1



2 18 2 14 2 14 2 12 2 11 2

2 18 2 14 2 14 2 12 2 11 2

1 125 1 128 1 128 1 131 1 133 1

1 149 1 152 1 152 1 157 1 161 1

1 137 1 140 1 140 1 143 1 146 1

1 61 1 64 1 63 1 63 1 61 1

1 51 1 52 1 51 1 50 1 48 1

1 118 1 121 1 121 1 123 1 124 1

2 36 1 31 1 30 1 26 1 23 1

2 37 1 32 1 31 1 27 1 24 1

1 238 1 244 1 245 1 256 1 263 1

1 215 1 219 1 220 1 229 1 235 1

1 56 1 57 1 56 1 55 1 53 1

2 14 2 49 1 48 1 47 1 45 1

1 95 1 98 1 97 1 98 1 99 1

1 123 1 126 1 126 1 129 1 131 1

2 52 1 53 1 52 1 51 1 49 1

1 42 1 37 1 36 1 32 1 29 1

1 62 1 65 1 64 1 64 1 62 1

1 110 1 113 1 113 1 114 1 115 1

1 114 1 117 1 117 1 118 1 119 1

1 178 1 182 1 182 1 188 1 192 1

1 243 1 249 1 250 1 261 1 268 1

2 14 2 50 1 49 1 48 1 46 1

1 241 1 247 1 248 1 259 1 266 1

1 90 1 93 1 92 1 93 1 94 1

1 132 1 135 1 135 1 138 1 140 1

1 136 1 139 1 139 1 142 1 145 1

1 97 1 100 1 100 1 101 1 102 1

1 199 1 203 1 204 1 212 1 216 1

1 230 1 235 1 236 1 247 1 253 1

1 86 1 89 1 88 1 89 1 89 1

1 70 1 73 1 72 1 73 1 72 1

No.

First Link to SigP Cleavage Mature potential

Seq name residue Seq size CDS Result Position MW pI MW pI glyc sites

Ctar-25 M 584 Ctar-25 SIG 19-20 66.831 5.48 64.931 5.41 0

Ctar-541 M 414 Ctar-541 SIG 19-20 45.063 9.16 42.987 9.18 5

Ctar-28 R 298 Ctar-28 34.277 8.51 0

Ctar-35 M 313 Ctar-35 SIG 20-21 36.402 5.68 34.341 5.68 0

Ctar-37 M 321 Ctar-37 SIG 16-17 36.396 7.47 34.802 7.07 0

Ctar-268 D 299 Ctar-268 32.663 5.58 4

Ctar-425 G 297 Ctar-425 32.958 5.13 1

Ctar-239 K 295 Ctar-239 33.385 9.55 0

Ctar-34 T 284 Ctar-34 33.214 6.04 0

Ctar-40 A 268 Ctar-40 30.569 8.56 0

Ctar-270 G 259 Ctar-270 29.196 7.29 0

Ctar-55 M 246 Ctar-55 SIG 19-20 26.902 4.67 24.976 4.6 6

Ctar-261 M 264 Ctar-261 SIG 20-21 28.767 4.18 26.752 4.15 13

Ctar-129 F 246 Ctar-129 26.764 5.85 0

Ctar-46 L 235 Ctar-46 25.32 8.68 0

Ctar-473 Q 234 Ctar-473 26.714 6.13 0

Ctar-104 M 223 Ctar-104 SIG 23-24 23.835 4.55 21.353 4.48 27

Ctar-789 R 226 Ctar-789 24.946 5.99 0

Ctar-49 M 213 Ctar-49 SIG 22-23 23.635 8.76 21.393 8.92 1

Ctar-345 M 222 Ctar-345 SIG 19-20 25.613 8.87 23.544 8.92 0

Ctar-769 M 233 Ctar-769 SIG 22-23 26.359 4.78 23.925 4.72 2

Ctar-173 V 260 Ctar-173 29.876 5.36 0

Ctar-47 L 200 Ctar-47 21.596 8.56 2

Ctar-151 T 171 Ctar-151 19.603 5.94 1

Ctar-790 M 167 Ctar-790 SIG 25-26 19.239 7.86 16.579 7.22 0

Ctar-4 M 163 Ctar-4 SIG 19-20 18.758 8.62 16.911 8.64 0

Ctar-150 M 158 Ctar-150 SIG 19-20 18.035 8.6 16.071 8.32 0

Ctar-95 M 157 Ctar-95 SIG 16-17 17.93 8.94 16.233 8.86 3

Ctar-118 A 156 Ctar-118 16-17 18.145 9.51 16.466 9.51 0

Ctar-371 M 158 Ctar-371 SIG 18-19 18.546 6.95 16.556 6.23 0

Ctar-195 M 148 Ctar-195 SIG 20-21 16.696 4.96 14.748 4.96 1

Ctar-370 M 148 Ctar-370 SIG 23-24 16.688 8.92 14.239 8.92 0

Ctar-293 D 143 Ctar-293 15.527 9.04 0

Ctar-438 R 137 Ctar-438 15.284 8.92 2

Ctar-183 C 137 Ctar-183 15.798 7.16 0

Ctar-613 G 141 Ctar-613 16.459 5.82 0

Ctar-10 G 134 Ctar-10 15.699 6.77 0

Ctar-11 G 134 Ctar-11 16.067 6.4 0

Ctar-33 M 115 Ctar-33 SIG 18-19 11.865 6.48 10.016 6.12 1

Ctar-280 R 127 Ctar-280 14.309 9.84 0

Ctar-581 N 123 Ctar-581 13.86 5.68 1

Ctar-32 G 111 Ctar-32 11.139 6.24 1

Ctar-18 I 115 Ctar-18 13.806 7.22 0

Ctar-1 M 114 Ctar-1 SIG 19-20 13.103 7.68 11.087 7.02 0

Ctar-300 M 113 Ctar-300 SIG 20-21 11.818 8.74 9.775 8.76 0

Ctar-556 S 105 Ctar-556 11.702 9.38 0

Ctar-363 V 107 Ctar-363 11.919 9.18 4

Ctar-194 P 150 Ctar-194 16.254 8.74 1

Ctar-761 M 121 Ctar-761 SIG 18-19 13.807 8.76 11.728 8.77 0

Ctar-31 N 91 Ctar-31 9.126 4.68 0

% Stop

Percent Percent Percent TMHMM Predicted membran Descripti codon?

Ser+Thr Gly Pro result Lenght helices e % outside % inside on (*)

10.6 5.9 4.7 584 0

ExpAA=4.18 First60=4.17 PredHel=0 Topology=o *

salivary alpha-glucosidase

16.4 7.1 5.5 414 0

ExpAA=4.90 First60=4.83 PredHel=0 Topology=o *

putative 41.9 kDa basic salivary protein

11.6 5 4 298 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o alpha-glucosidase - fragment

11 4.1 2.5 313 0

ExpAA=0.28 First60=0.28 PredHel=0 Topology=o *

long form D7 salivary protein

7.7 6.4 3.4 321 0

ExpAA=0.11 First60=0.11 PredHel=0 Topology=o *

long form D7 salivary protein

9.9 9.9 7.2 299 0

ExpAA=0.05 First60=0.00 PredHel=0 Topology=o secreted serine protease possibly involved with

11.3 7.3 6 297 0

ExpAA=0.19 First60=0.00 PredHel=0 Topology=o alpha-amylase - fragment

11 11 6 295 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o putative salivary Gram negative bacteria-binding

10.4 4.2 1.7 284 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

long form D7 salivary protein - truncated at 5 pri

7.7 6.6 2.9 268 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o long form D7clu1 salivary protein - fragment

9.5 7.6 4.2 259 0

ExpAA=1.09 First60=0.00 PredHel=0 Topology=o *

trypsin-like salivary secreted protein - truncated

8 9.6 5.2 246 0

ExpAA=0.11 First60=0.11 PredHel=0 Topology=o *

30 kDa salivary gland allergen/Aegyptin

19 7.8 7.5 264 0

ExpAA=4.14 First60=4.14 PredHel=0 Topology=o *

putative salivary secreted mucin 3

13.6 6 4.4 246 0

ExpAA=0.05 First60=0.04 PredHel=0 Topology=o *

putative 30.5 kDa secreted protein - truncated a

12.6 5.4 2.9 235 0

ExpAA=0.43 First60=0.01 PredHel=0 Topology=o *

30.5 kDa secreted protein 1 - truncated at 5 prim

9.2 8 3.8 234 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o deoxyribonuclease I - fragment

21.6 6.2 4.8 223 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o *

putative 30 kDa allergen-like protein

8.7 10.9 6.1 226 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o alpha-amylase - fragment

13.4 6.9 6.9 213 0

ExpAA=0.28 First60=0.28 PredHel=0 Topology=o salivary secreted*protein of the Aegyptin family

14.6 5.8 4.9 222 0

ExpAA=1.21 First60=1.21 PredHel=0 Topology=o *

putative 23.4 kDa salivary protein

11.8 4.2 3.4 233 0

ExpAA=0.07 First60=0.07 PredHel=0 Topology=o *

conserved hypothetical protein

12.1 6.4 1.5 260 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

long form D7 - truncated at 5 prime

13.3 5.9 3 200 0

ExpAA=0.53 First60=0.01 PredHel=0 Topology=o *

30.5 kDa secreted protein 1 - truncated at 5 prim

12.1 5.2 2.3 171 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

putative salivary antigen 5 family protein 1 - trun

11.8 6.5 3.5 167 0

ExpAA=7.80 First60=7.80 PredHel=0 Topology=o *

16 kDa salivary peptide

9.6 8.4 3 163 0

ExpAA=10.20 First60=9.77 PredHel=0 Topology=o 17.2 kDa salivary* peptide

10.6 7.5 1.9 158

ExpAA=15.71 First60=15.711PredHel=1 Topology=o4-26i

13.9 2.5 83.5 *

putative 13.1 kDa salivary protein

13.8 8.1 3.8 157 0

ExpAA=0.06 First60=0.06 PredHel=0 Topology=o 15.8 kDa salivary* peptide

11.9 6.9 1.9 156

ExpAA=21.01 First60=20.901PredHel=1 Topology=o4-25i

13.5 2.6 84 16.7 kDa salivary* peptide - truncated at 5 prime

9.9 4.3 1.9 158 0

ExpAA=0.11 First60=0.11 PredHel=0 Topology=o salivary short D7*protein

9.3 6 2 148 0

ExpAA=2.05 First60=2.05 PredHel=0 Topology=o *

putative salivary odorant binding protein

14.6 5.3 2 148

ExpAA=11.81 First60=11.810PredHel=0 Topology=o lysozyme *

11.6 11.6 4.8 143 0

ExpAA=0.03 First60=0.03 PredHel=0 Topology=o *

alpha-amylase - truncated at 5 prime

15.1 7.2 5.8 137 0

ExpAA=0.62 First60=0.51 PredHel=0 Topology=o venom allergen 5* - truncated at 5 prime

10.8 8.6 1.4 137 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=i *

putative 17.5 kDa salivary peptide - truncated at

16.7 6.3 2.8 141 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o 16.8 kDa salivary* protein - truncated at 5 prime

16.2 6.6 2.2 134 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o 16.8 kDa salivary* peptide - truncated at 5 prime

11 6.6 2.2 134 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=i 16.8 kDa salivary* peptide - truncated at 5 prime

6.8 23.9 9.4 115 0

ExpAA=7.14 First60=7.14 PredHel=0 Topology=o *

putative GQP-rich salivary protein

13.2 7.8 3.9 127 0

ExpAA=0.98 First60=0.98 PredHel=0 Topology=o *

serine protease htra2 - truncated at 5 prime

16.8 6.4 2.4 123 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o *

salivary mucin - truncated at 5 prime

5.3 31 13.3 111 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

putative GQP-rich salivary protein - truncated at

13.7 6.8 2.6 115 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o 16.7 kDa salivary peptide - fragment

13.8 5.2 2.6 114 0

ExpAA=1.07 First60=1.07 PredHel=0 Topology=o 16.7 kDa salivary* family member

16.5 8.7 3.5 113

ExpAA=15.18 First60=15.180PredHel=0 Topology=o *

putative salivary cysteine-rich peptide

10.3 11.2 4.7 105 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o serine protease -*truncated at 5 prime

12.8 8.3 4.6 107 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o serine protease -*truncated at 5 prime

11.8 12.4 6.5 150

ExpAA=21.69 First60=0.00 PredHel=1 Topology=o122-144i

1 14.7 81.3 *

4 salivary alkaline phosphatase - truncated at 5 pr

4.1 10.6 2.4 121 0

ExpAA=0.03 First60=0.03 PredHel=0 Topology=o putative 7.8 kDa *secreted peptide

5.4 30.1 12.9 91 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

putative GQP-rich salivary protein - truncated at

Best

match to Length of First

Salivary SAL-DIP Extent of best % Match residue of

Class motifs database E value Match Score match match % identity length match

s/enz malt 0.0 gi|126713

Probable maltase precursor 854 559 579 71 97 21

s/41.9 1E-151 salivary protein 527

putative 41.9 kDa basicgi|38350631 412 412 65 100 1

s/enz maltase 1E-108 gi|56417392

probable salivary maltase precursor 381 324 579 60 56 217

s/d7l long motif - less degenerate pattern

1E-159 gi|16225986

D7 Lipid binding form D7clu12 salivary protein |Lipid 551 binding mosquito D7313

313 83 100 1

pattern |Lipid binding D7 WC framework |

s/d7l long motif - less salivary protein

1E-143 gi|16225983

D7 Lipid binding form D7clu1degenerate pattern |Lipid 500 binding D7 WC framework |

301 311 77 97 13

7E-46 Ag_sal_PPOA2 with 285 365

s/enz serine protease secreted serine protease possibly involved175 prophenoloxidase activation 35 78 62

s/enz amylase 1E-131 gi|1703297 457

Alpha-amylase I precursor (1,4-alpha-D-glucan glucanohydrolase)

297 737 70 40 346

s/imm prp 1E-141 gi|56417408 493

putative salivary Gram negative bacteria-binding protein

293 371 77 79 26

s/d7l long form D7clu12 salivary protein

1E-145 gi|16225986 505

Lipid binding mosquito D7 pattern |Lipid binding D7 WC framework |284 313 84 91 30

s/d7l 1E-123 gi|16225983

long form D7clu1 salivary protein 434 268 311 75 86 46

3E-045 gi|94468372

s/enz serine protease trypsin-like salivary secreted protein 173 244 330 41 74 69

s/30 30 kDa salivary gland gi|56417504

|Aegyptin mosquito stringent pattern115

Aegyptin stringent pattern3E-023 allergen 30k-3 100 | 271 41 42 29

s/muc 2E-089 gi|94468382

putative salivary secreted mucin 3 320 263 268 61 98 1

s/30.5 2E-041 gi|18568320

putative 30.5 kDa secreted protein 160 228 275 36 83 24

s/30.5 putative 30.5 kDa

1E-033 gi|94468432

30.5 kDa family cys pattern | secreted protein second134 member

family 218 275 33 79 59

s/enz dnase 2E-019 SP11

40 kDa salivary protein gi|74486555 87.4 220 383 27 57 26

s/30 3E-055

putative salivary proteingi|38350685 206 230 228 55 101 1

s/enz amylase salivary amylase1E-66 Ag_salAmy 244 223 876 53 25 428

s/30 salivary proteinmosquito |Aegyptin mosquito stringent pattern | 214

Basic tail type 3 |Aegyptin5E-090 gi|38350637 321 198 81 93 17

s/23.4 1E-117 gi|38350639

putative 23.4 kDa salivary protein 410 222 222 83 100 1

s/hyp37 0.17

putative salivary proteingi|38350685 27.7 46 228 26 20 4

s/d7l 2E-016 gi|56417448

long form D7Bclu1 salivary protein d7l1 77.8 194 332 29 58 58

s/30.5 8E-026 gi|94468432 family 168

putative 30.5 kDa secreted protein second108 member 275 34 61 59

s/ag5 1E-100 gi|38350629

putative salivary antigen 5 family protein 1 356 171 255 94 67 85

s/16.7 16 kDa kDa family |Culex salivary 16.8 71.6

6E-015

Culex salivary 16.8 salivary peptidegi|38350665 kDa family-less degenerate pattern 28

147 158 | 93 20

s/16.7 putative 17.5 kDa |Culex peptide

2E-053 gi|38350703 199

Culex salivary 16.8 kDa familysalivary salivary 16.8 kDa family-less degenerate pattern 60

146 171 | 85 21

s/16.7 5E-049 gi|38350601

putative 13.1 kDa salivary protein 184 104 132 75 79 21

s/16.7 putative 15.8 kDa |Culex peptide

4E-044 gi|38350705 168

Culex salivary 16.8 kDa familysalivary salivary 16.8 kDa family-less degenerate pattern 58

138 156 | 88 20

s/16.7 putative 16.7 kDa |Culex peptide

9E-040 gi|38350695 154

Culex salivary 16.8 kDa familysalivary salivary 16.8 kDa family-less degenerate pattern 50

138 159 | 87 24

s/d7s 6E-058 gi|38350655

putative salivary short D7 protein 3 214 156 161 61 97 1

s/obp 3E-010 gi|38350597

putative salivary odorant binding protein 155.8 109 148 28 74 30

s/imm amp 2E-39 Ag_sal_Lyzo1

abundant salivary lysozyme 152 135 140 50 96 9

s/enz amylase 5E-037

putative alpha-amylase gi|4887104 144 143 497 50 29 358

s/ag5 1E-050 gi|18568308

putative secreted protein 189 137 259 61 53 123

s/16.7 putative 17.5 kDa |Culex peptide

6E-042 gi|38350703 160

Culex salivary 16.8 kDa familysalivary salivary 16.8 kDa family-less degenerate pattern 54

138 171 | 81 29

s/16.7 putative 16.8 kDa |Culex protein

4E-013 gi|38350691 65.5

Culex salivary 16.8 kDa familysalivary salivary 16.8 kDa family-less degenerate pattern 32

118 155 | 76 34

s/16.7 putative 16.7 kDa |Culex peptide

2E-025 gi|38350695 105

Culex salivary 16.8 kDa familysalivary salivary 16.8 kDa family-less degenerate pattern 39

136 159 | 86 26

s/16.7 16 kDa kDa family |Culex salivary 16.8 132

2E-033

Culex salivary 16.8 salivary peptidegi|38350665 kDa family-less degenerate pattern 48

137 158 | 87 25

s/GQP

0.001 gi|94469106

s/enz serine protease syndecan binding protein 33.9 59 333 35 18 166

s/muc 5E-060

putative salivary mucin gi|38350653 220 123 260 86 47 138

s/GQP

s/16.7 16 kDa kDa family |Culex salivary 16.8 110

7E-027

Culex salivary 16.8 salivary peptidegi|38350665 kDa family-less degenerate pattern 44

118 158 | 75 29

s/16.7 putative 16.7 kDa |Culex peptide

6E-017 gi|38350695 77.4

Culex salivary 16.8 kDa familysalivary salivary 16.8 kDa family-less degenerate pattern 40

93 159 | 58 24

s/cysrich 2E-057 gi|38350651

putative salivary cysteine-rich peptide 212 113 113 86 100 1

s/enz serine protease serine protease8E-023 gi|56199562 96.7 91 259 49 35 170

s/enz serine protease 8E-011 gi|94468648

polyserase 2-like protein 57 89 537 30 17 143

s/enz phosphatase 1E-047 gi|94469242

salivary alkaline phosphatase 179 110 562 74 20 414

s/7.8 7E-009 gi|56417476

putative 7.8 kDa secreted peptide 50.8 64 96 34 67 27

s/GQP

Best

match to

First NR Length of First First

residue of protein Extent of best % Match residue of residue of

sequence database E value Match Score match match % identity length match sequence

22 alpha-glucosidase 0.0 gi|170062220 1096 584 584 89 100 1 1

1 1E-159 salivary protein 565

putative 41.9 kDa basicgi|38350631 412 412 69 100 1 1

1 1E-147 gi|170062220

alpha-glucosidase 525 325 584 81 56 218 1

1 1E-164 gi|16225986

long form D7clu12 salivary protein 582 313 313 87 100 1 1

12 1E-140 gi|16225983

long form D7clu1 salivary protein 500 301 311 77 97 13 12

16 1E-170 gi|170067273

elegaxobin-2 [Culex quinquefasciatus] 602 299 427 94 70 98 1

1 alpha-amylase I1E-158 gi|170065228 561 297 533 89 56 142 1

3 1E-138 gi|56417408 493

putative salivary Gram negative bacteria-binding protein293 371 77 79 26 3

1 1E-150 gi|16225986

long form D7clu12 salivary protein 533 284 313 89 91 30 1

1 1E-120 gi|16225983

long form D7clu1 salivary protein 434 268 311 75 86 46 1

1 5E-086 gi|170073628 320 259

trypsin-like salivary secreted protein [Culex quinquefasciatus] 311 61 83 67 1

22 3E-089 gi|170033701 331

30 kDa salivary gland allergen Aed a 3 [Culex quinquefasciatus] 249

251 68 101 1 1

1 RNA

virus-induced 1E-116 gi|170054977 421 246 263 86 94 8 23

1 1E-112 protein [Culex 409

conserved hypothetical gi|170043113 quinquefasciatus] 246 279 82 88 27 1

26 1E-107 gi|170043115 391 235

30.5 kDa secreted protein 30.5k-1 [Culex quinquefasciatus] 268 83 88 34 1

18 1E-131

deoxyribonuclease I gi|170033931 470 234 410 94 57 108 1

1 7E-079 gi|170031423

salivary protein 296 229 227 71 101 1 1

3 1E-118 gi|170037398

alpha-amylase [Culex quinquefasciatus] 428 225 497 92 45 47 1

16 1E-108 gi|38350637

salivary protein 393 214 214 91 100 1 1

1 1E-113 gi|38350639

putative 23.4 kDa salivary protein 410 222 222 83 100 1 1

1 3E-012 protein [Culex 75.5

conserved hypothetical gi|170052919 quinquefasciatus] 205 298 28 69 99 26

17 5E-089 gi|157119319

D7 protein, putative [Aedes aegypti] 330 255 311 65 82 57 1

26 1E-079 gi|170043115 298 182

30.5 kDa secreted protein 30.5k-1 [Culex quinquefasciatus] 268 82 68 34 1

1 3E-097 gi|170067964 356 171

salivary secreted antigen-5 precursor AG5-3 [Culex quinquefasciatus]

255 94 67 85 1

25 1E-081 [Culex quinquefasciatus]

16 kDa salivary peptidegi|170038647 305 165 168 86 98 4 3

20 1E-072 gi|170057179

17.2 kDa salivary peptide 274 164 162 76 101 1 1

21 5E-068 gi|170069959

13.1 kDa salivary protein 259 160 160 73 100 1 1

20 1E-047 gi|170069938

15.8 kDa salivary peptide 191 157 156 59 101 1 1

19 1E-080 gi|170069957

16.7 kDa salivary peptide 301 156 159 85 98 4 1

1 D7 protein 3

salivary short 2E-058 gi|170059545 227 156 161 65 97 1 1

28 3E-057 protein [Culex 223

conserved hypothetical gi|170050697 quinquefasciatus] 149 144 71 103 1 1

12 4E-079 gi|170038550

lysozyme [Culex quinquefasciatus] 296 148 148 91 100 1 1

2 1E-074 gi|170037398

alpha-amylase [Culex quinquefasciatus] 281 143 497 89 29 355 1

1 3E-072 gi|170035516

venom allergen 5 273 137 258 91 53 122 1

1 1E-069 gi|170050106

17.5 kDa salivary peptide 264 137 162 86 85 26 1

4 4E-053 gi|170031282 209

16.8 kDa salivary protein [Culex quinquefasciatus] 137 303 69 45 166 1

1 1E-033 gi|170050708

16.7 kDa salivary peptide 145 136 164 45 83 24 1

1 2E-032 gi|170050708

16.7 kDa salivary peptide 140 136 164 44 83 24 1

3E-033 gi|38350697

putative GQP-rich salivary protein 143 157 157 55 100 1 1

52 5E-053 gi|157113259

serine protease htra2 [Aedes aegypti] 209 125 437 83 29 313 1

1 salivary mucin 2E-056 gi|170069036 221 123 479 86 26 357 1

5E-038 gi|38350697

putative GQP-rich salivary protein 159 122 157 71 78 25 1

1 1E-026 gi|170050708

16.7 kDa salivary peptide 121 117 164 46 71 28 1

23 1E-045 gi|170069955

16.7 kDa salivary peptide 185 114 163 76 70 1 1

1 6E-059 gi|170072150 229

salivary cysteine-rich peptide [Culex quinquefasciatus]113 113 93 100 1 1

4 5E-047 aegypti]

serine protease [Aedes gi|157115317 189 104 247 79 42 144 1

18 3E-046 gi|170060533

serine protease 186 106 504 82 21 398 1

2 8E-046 gi|157112288

alkaline phosphatase [Aedes aegypti] 185 146 562 62 26 414 2

31 3E-005 gi|56417476

putative 7.8 kDa secreted peptide 50.8 64 96 34 67 32 31

5E-029 gi|38350697

putative GQP-rich salivary protein 129 96 157 72 61 63 2

Orientatio Best Best

Number n of match to match to Function Function

of assemble KOG General GO descripto Function second

segments d output Species database E value class database E value rs parent parent

1 FOR Alpha-amylaseE-113 Carbohydrate transport and metabolism

1

Culex quinquefasciatus] quinquefasciatus Larval visceral protein H - Drosophila melanogaster - alpha-glucosidase activity - gl

0 alpha\-glucosidase activity||glucosidase activity||hydrolase a

catalytic activity

hydrolase activity

1 FOR RNA binding protein General function prediction only

0.30

Culex pipiens quinquefasciatus RBM12/SWAN

1 FOR Culex quinquefasciatus] quinquefasciatus

Alpha-amylaseE-039 Carbohydrate transport and metabolism

7 protein alpha\-glucosidase activity||glucosidase activity||hydrolase a

catalytic activity

hydrolase activity

Larval visceral4E-60 H - Drosophila melanogaster - alpha-glucosidase activity - gl

1 FOR Culex pipiens quinquefasciatus

1 FOR dsRNA-activated protein kinase inhibitor P58, contains TPR and DnaJ domains

0.041 Defense mechanisms

Culex pipiens quinquefasciatus

1 FOR Trypsin transport Drosophila melanogastercatalytic activity activity||serine\-type peptidase a

1E-97 serine\-type endopeptidase

Culex quinquefasciatus 8E-043 Amino acid CG5390 -and metabolism hydrolase activity

- serine-type endopeptidase activity

1 FOR Culex quinquefasciatus] quinquefasciatus

Alpha-amylaseE-097 Carbohydrate transport and metabolism 1 precursor - activity

9 Alpha-amylase catalytic Drosophila ananassae alpha-amylase

activity||glucosidase

Amy35, Amy1:7E-90 oligo\-1\,6\-glucosidase hydrolase activity -activity||hydrola

1 FOR Aedes albopictus 4E-29 protein binding||binding

binding bacterial binding

Beta-1,3-glucan-bindingbacterial 1 precursor - Manduca sexta - regulation of innate i

1 FOR Uncharacterized conserved protein

0.53 Function unknown

Culex pipiens quinquefasciatus

1 FOR dsRNA-activated protein kinase inhibitor P58, contains TPR and DnaJ domains

0.068 Defense mechanisms

Culex pipiens quinquefasciatus

1 FOR Trypsin transport Drosophila melanogaster - serine-type endopeptidase activity

2E-11

Culex quinquefasciatus 2E-010 Amino acid CG9673 -and metabolism

1 FOR WD40 repeat 0.007 protein Bop1, involved in ribosome biogenesis

Culex quinquefasciatus nucleolar Translation, ribosomal structure and biogenesis

1 FOR Uncharacterized conserved protein virus-induced RNA 1 - Drosophila melanogaster - defense response to virus

0.002 Function

Culex quinquefasciatus] quinquefasciatus unknown 6E-09

1 FOR Predicted alpha/beta General function

Culex quinquefasciatus 0.22 hydrolase BAT5 prediction only

1 FOR Culex quinquefasciatus

1 FOR Culex quinquefasciatus] quinquefasciatus

1 FOR Uncharacterized conserved protein

3E-004 General

Culex quinquefasciatus] quinquefasciatus function prediction only

1 FOR Alpha-amylase Amy35, Amy1:1E-76 oligo\-1\,6\-glucosidase hydrolase activity -activity||hydrola

Alpha-amylase catalytic Drosophila ananassae alpha-amylase

Culex quinquefasciatus 1E-083 Carbohydrate transport and metabolism 1 precursor - activity activity||glucosidase

1 FOR RhoA GTPase 0.11 Signal transduction

effector

Culex pipiens quinquefasciatus DIA/Diaphanous mechanisms, Cytoskeleton

1 FOR Culex pipiens quinquefasciatus

1 FOR Vacuolar assembly/sorting protein trafficking, secretion, and vesicular transport

Culex quinquefasciatus 0.62 IntracellularVPS41

1 FOR Exocyst complex subunit

Aedes aegypti 0.36 Intracellular trafficking, secretion, and vesicular transport

1 FOR Culex quinquefasciatus

1 FOR Defense-related protein containing SCP domain 1E-23 molecular_function

CG32679 molecular_function

Culex quinquefasciatus 2E-021 Function unknown - Drosophila melanogaster - extracellular region

1 FOR Culex quinquefasciatus

1 FOR Sulfide:quinone oxidoreductase/flavo-binding protein

Culex quinquefasciatus 0.28 Energy production and conversion

1 FOR Culex quinquefasciatus

1 FOR Uncharacterized conserved protein

Culex quinquefasciatus 0.55 Function unknown

1 FOR Culex quinquefasciatus

1 FOR Culex quinquefasciatus

1 FOR Molecular chaperone Posttranslational

Odorant-binding proteinodorant binding||bindingodorant binding binding - sensory

4E-09 99a - Drosophila melanogaster - odorant

chaperones

Culex quinquefasciatus 0.18 (DnaJ superfamily) modification, protein turnover,binding

1 FOR Culex quinquefasciatus Drosophila melanogaster - lysozyme activity\, hydrolyzing humoral r

catalytic activity

hydrolase activity

Lysozyme P - 1E-25 lysozyme activity||hydrolaseactivity - antimicrobialO\-glycosy

1 FOR Alpha-amylase Amylase proximal - Drosophila

1E-46 oligo\-1\,6\-glucosidase hydrolase activity activity||hydrola

catalytic activity

activity||glucosidase

Culex quinquefasciatus 3E-054 Carbohydrate transport and metabolism melanogaster - alpha-amylase activity - calcium ion

1 FOR Defense-related proteinFunction SCP domain 3E-24

1E-016 containing CG32679

Culex quinquefasciatus] quinquefasciatus unknown - Drosophila melanogaster - extracellular region

1 FOR Culex quinquefasciatus

1 FOR Culex quinquefasciatus

1 FOR Culex quinquefasciatus

1 FOR Culex quinquefasciatus

1 FOR 5'-3' exonuclease HKE1/RAT1

3E-004 Replication, recombination and repair, RNA processing and modification

Culex pipiens quinquefasciatus

1 FOR Aedes aegypti

Serine protease

2E-019 Posttranslational modification, protein turnover,catalytic activity activity||serine\-type peptidasesa

HTRA2, OMI, PRSS25: serine\-type chaperones mitochondrial precursor - Homo a

1E-20 Serine protease HTRA2,

endopeptidasehydrolase activity

1 FOR Culex quinquefasciatus] quinquefasciatus

2 FOR 5'-3' exonuclease HKE1/RAT1

3E-005 Replication, recombination and repair, RNA processing and modification

Culex pipiens quinquefasciatus

1 FOR Culex quinquefasciatus

1 FOR Culex quinquefasciatus

1 FOR Serine proteinase inhibitor (KU family) with thrombospondin repeats

CG30197 - Drosophila melanogaster - biological_process

3E-24

Culex quinquefasciatus 0.24 Posttranslational modification, protein turnover, chaperones

1 FOR Trypsin

Aedes aegypti transport Drosophila melanogaster - proteolysis

4E-26

2E-022 Amino acid CG4386 -and metabolism

1 FOR Trypsin 1E-009 Amino transport Drosophila melanogaster - proteolysis

7E-12

Culex quinquefasciatus] quinquefasciatus acid CG9631 -and metabolism

1 FOR Alkaline phosphatase Alkaline phosphatase 4 alkaline phosphatase activity||phosphatase activity||phospho

2E-30 - Drosophila melanogaster - alkaline phosphatase activity -

Aedes aegypti] aegypti 4E-023 Inorganic ion transport and metabolism hydrolase activity

catalytic activity

1 FOR Aedes albopictus

1 FOR 5'-3' exonuclease HKE1/RAT1

5E-005 Replication, recombination and repair, RNA processing and modification

Culex pipiens quinquefasciatus

Compone

E value of nt Compone E value of Process Process

functional descripto Compone nt second compone descripto Process second

GO # GO rs nt parent parent GO # nt GO rs parent parent GO #

GO:0004558 1E-147



GO:0004558 2E-54





GO:0004252 4E-52

GO:0004574 6E-76

GO:0008367 region

4E-29 extracellularextracellular region GO:0005576 of innate bacterial binding

GO:0045088

4E-29 ®ulation binding immune response||regulation of inflammatory resp





catalytic activity

hydrolase activity

GO:0006508

proteolysis||cellular protein metabolic process||cellular macromolecule m



molecular_function GO:0051607

defense response to virus||response to virus||response to other organis









GO:0004574 1E-67









GO:0003674 4E-11 molecular_function

biological_process GO:0008150









GO:0005549 region

4E-09 extracellularextracellular region binding odorant binding

GO:0007606

GO:0005576 4E-09 sensory perception of chemical stimulus||sensory perception||neurologic

GO:0003796 space||apoplast||extracellular region

region catalytic activity

hydrolase to wounding||response to external stim

GO:0006954

1E-22 extracellularextracellularapoplast GO:0005615 1E-22 inflammatory response||response activity

GO:0004574 3E-45

region

extracellularextracellular region GO:00055760.000003









GO:0004252 external membrane\-bounded organelle||intracellular organelle||outer membrane\-bounded periplasmic space||externa

outer membrane\-bounded 1E-20 proteolysis||cellular activity

GO:0005634 hydrolase activity

GO:0006508

1E-20 nucleus||intracellularencapsulating structure part periplasmic space catalyticprotein metabolic process||cellular macromolecule m

catalytic hydrolase activity

biological_process activity GO:0008150

of blood coagulation||regulation of macroautophagy||antifun

hydrolase activity

®ulation catalytic activity GO:0030193

space||apoplast||extracellular region

region catalytic activity

hydrolase activity

GO:0006508

extracellularextracellularapoplast GO:0005615 2E-07 proteolysis||cellular protein metabolic process||cellular macromolecule m

GO:0004035 plasma membrane||intrinsic to

GO:0046658 2E-30 epithelial fluid transport||fluid

to membrane||coatedactivity

hydrolase membrane||membrane

GO:0042045

2E-30 anchored tomembrane coated membrane plasma membrane||intrinsiccatalytic activity transport||transport||cellular localization||lo

Best Best Best Best

E value of match to match to match to match to

process CDD All CDD PFAM SMART COG General

GO database E value domains database E value database E value database E value class

PRK10933 9E-076 Alpha-amylaseE-069 6e-069|

2 3E-042 AmyA, Glycosidases

PRK10785 9e-021| GlgB 1e-013| PRK09441

PRK10933 9e-076| Alpha-amylase Aamy AmyA 1e-067| Aamy 4e-040|3E-068 Carbohydrate transport and metabo

COG5222 0.14 TRAP_240kDa |

COG5222 | TRAP_240kDa0.19 0.040 General function prediction Zn-finge

Uncharacterized conserved protein, contains RING only

PRK10933 1E-011 Alpha-amylaseE-006 AmyA, 9E-008

PRK10933 1e-011| AmyA23e-007| Alpha-amylase 7e-006| RecC | Glycosidases Carbohydrate transport and metabo

PhBP 0.018 PBP_GOBP 0.40 PhBP

PhBP 0.018| 2E-004

PhBP 0.009 PBP_GOBP 0.018

PhBP 0.009| PBP_GOBP 0.067| PhBP 0.39 Amino acid transport and metabolism

1E-004 LasB, Zinc metalloprotease (elastase)

Tryp_SPc 5E-050 Trypsin 6E-035 Tryp_SPc 9E-050 Secreted trypsin-like Posttranslational modification, protei

COG3591 0.098| DUF316 0.100|

Tryp_SPc 5e-050| Tryp_SPc 8e-048| Trypsin 2e-034| COG5640 1e-015| 3E-016 serine protease

9

Alpha-amylaseE-036 Alpha-amylaseE-036 Aamy

3 3E-007 AmyA, Glycosidases Carbohydrate

8E-010

Alpha-amylase 9e-036| AmyA 3e-009| Aamy 2e-005| PRK09441 0.005| PulA 0.026| PRK12797 | transport and metabo

4E-29 GH16_beta_GRP9E-085 Glyco_hydro_16 GH16_laminarinase 1e-032| Glyco_hydrolase_16 3e-019| SKN1 6e-010| Glyco_hydro_16 2e

GH16_beta_GRP 9e-085|7E-010 2E-010 Carbohydrate transport

SKN1, Beta-glucanase/Beta-glucan synthetase and metabo

PhBP 0.64 PhBP | PBP_GOBP 0.49 PhBP 0.007

PhBP 0.15 PBP_GOBP 0.092 PhBP

PhBP | PBP_GOBP | 0.002

0.00002 Tryp_SPc 4E-009 Trypsin 4E-007

Tryp_SPc 4e-009| Trypsin 1e-006| Tryp_SPc 4E-011

MDN1 7E-005 Daxx 7E-004 | COG5137 |2E-005 | General von Willebrand factor type

CDC27

MDN1 7e-005| Daxx 0.002| CobT 0.100| CobT | PRK12678MDN1, AAA ATPase containing function prediction only A

6E-09 COG2194 0.072 CobT 0.072 Predicted membrane-associated, metal-dependent only

COG2194 0.072| CobT | TFIIF_alpha | CobT | Cwf_Cwc_15 | 0.022 General function prediction hydrolas

nrdG 0.27 nrdG |

RHD3 0.32 RHD3 | RHD3 0.090 0.81

Myosin heavy chain Cytoskeleton

NUC 1E-018 Endonuclease_NS

4E-016 NUC 1E-007 NUC1, DNA/RNA endonuclease G, NUC1

NUC 1e-018| Endonuclease_NS 1e-015| NUC1 7e-006| NUC 1e-005| 2E-006 Nucleotide transport and metabolism

CobT 0.003 CobT 8E-004 Nucleosome binding factor SPN, SPT16 | Pneumo_att_G |

0.062 Transcription / DNA replication, reco

CobT 0.003| PRK08581 0.005| Herpes_DNAp_acc 0.018| PRK07406 0.027| COG5406 | PRK12372subunit

9

Alpha-amylaseE-032 Alpha-amylaseE-032 Aamy

2 2E-021 3e-004| PulA 6E-012 Carbohydrate transport and metabo

0.003|

Alpha-amylase 9e-032| Aamy 2e-019| AmyA 2e-011| GlgB AmyA, GlycosidasesPRK09441 0.005| malS 0.063| PRK107

DUF705 0.18 DUF705

DUF705 | COG4016 | 0.052 0.25 conserved in archaea

Uncharacterized proteinFunction unknown

COG5291 0.30 COG5291 | Filo_glycop | 0.13 0.091 Function unknown

Predicted membrane protein

Cucumo_coat 0.097 Cucumo_coat 0.027

Cucumo_coat 0.097|

PBP_GOBP 0.044 0.044| PhBP

PBP_GOBPPBP_GOBP |0.012 PhBP 0.002

RHD3 0.17 RHD3 | RHD3 0.049 0.47

Myosin heavy chain Cytoskeleton

4E-11 SCP_euk 2E-023 SCP 2E-019 SCP 8E-020

SCP_euk 2e-023| SCP 5e-019| SCP 6e-018| SCP_CRISP 2e-009| SCP_GLIPR-1_like 2e-009| SCP 3e-008| SCP_HrT



DgoK 0.13 Ceramidase_alk.38

DgoK | PRK04542 | 0 0.043 Carbohydrate transport and metabo

DgoK, 2-keto-3-deoxy-galactonokinase

GltP 0.47 Ppx-GppA 0.14 TOPEUc 0.15 Energy production

GltP | Ppx-GppA | Ricin_B_lectin | beta_tubulin | 0.20 GltP, Na+/H+-dicarboxylate symporters and conversion

SMP2 0.52 SMP2 | MAM 0.16 protein function in plasmid mainten

0.20 SMP2, UncharacterizedGeneral involved prediction only

CDtoxinA 0.17 CDtoxinA | CDtoxinA 0.049 CENPB 0.53

PhBP 6E-004 DUF1789 0.022 PhBP PBP_GOBP | 0.030 General function prediction only

PhBP 6e-004| DUF1789 0.075| COG3271 0.095| 8E-006 Predicted double-glycine peptidase

4E-09 PBP_GOBP 2E-006 2e-006| PhBP 1e-005|

PBP_GOBPPBP_GOBP 6E-007 PhBP 2E-007

1E-22 LYZ1 6E-038 Lys 5E-030 LYZ1

LYZ1 6e-038| LYZ1 1e-033| Lys 2e-029| 2E-035

Aamy_C 8E-023 Alpha-amylase_C

5E-011 2e-010|

Aamy_C 8e-023| Alpha-amylase_CAamy_C 0.27 ribonucleoside-triphosphate reducta

1E-024 NrdD, Oxygen-sensitiveNucleotide transport and metabolism

SCP_euk 1E-014 SCP 8E-010 SCP 6E-012

SCP_euk 1e-014| SCP 4e-010| SCP 3e-009| SCP_GAPR-1_like 8e-005| SCP_PR-1_like 3e-004| SCP_GLIPR-1_like 0



MIR 0.51

SPC22 0.39 SPC22 | SPC22 0.12 0.54 Coenzyme metabolism

BioF, 7-keto-8-aminopelargonate synthetase and related en

CodB 0.18 CodB | HormR 0.059 Nucleotide transport and metabolism

0.059 CodB, Purine-cytosine permease and related proteins

PRK05325 0.013 Sporozoite_P67

0.005 PRP 0.19 CobT, Cobalamin biosynthesis protein DUF390 | PRK0776

0.62 Coenzyme metabolism

PRK05325 0.013| PRK12678 0.014| Sporozoite_P67 0.015| Herpes_LMP2 | GAL11 | PRK10590 |CobT (nicotinate-mon

8E-013

1E-20 PDZ_serine_prot PDZ 7E-006 PDZ 3E-009 DegQ, Trypsin-like serine proteases, typically 3e-006| protei

4E-009 Posttranslational modification, PDZ

PDZ_serine_protease 8e-013| DegQ 1e-008| PDZ_metalloprotease 2e-008| PDZ 2e-007| PDZ_signaling periplasmic, c

0.72 Function unknown

Uncharacterized paraquat-inducible protein B

0.001

Sporozoite_P67 Sporozoite_P67

3E-004 PRP 0.83

Sporozoite_P67 0.001| PRK12678 0.007| Herpes_LMP2 0.062| PRK05325 | secA | PRK10590 | Herpes_UL32 | Totivir

CodB 0.11 CodB | PRK05937 | 0.035 Nucleotide transport and metabolism

CodB, Purine-cytosine permease and related proteins

PRK12904 0.42 PRK12904 | 0.60 General function prediction only

Predicted acetyltransferase

3E-24 PRK10524 0.29 PRK10524 |

1E-21 Tryp_SPc 2E-029 Trypsin 2E-019 Tryp_SPc 8E-029 Secreted trypsin-like Posttranslational modification, protei

Tryp_SPc 2e-029| Tryp_SPc 5e-027| Trypsin 6e-019| COG5640 1e-008| 3E-009 serine protease

2E-07 Tryp_SPc 2E-010 Trypsin 7E-006 Tryp_SPc 4E-012 Secreted trypsin-like Posttranslational modification, protei

Tryp_SPc 2e-010| Tryp_SPc 2e-010| Trypsin 2e-005| COG5640 0.002| 5E-004 serine protease

2E-30 alkPPc 4E-018 Alk_phosphatase

4E-015 alkPPc 3e-010| PhoA, Alkaline phosphatase

alkPPc 4e-018| Alk_phosphatase 1e-014| alkPPc6E-020 PhoA 2e-004| 8E-005 Inorganic ion transport and metaboli



0.003

Sporozoite_P67 Sporozoite_P67

9E-004 PRP 0.60

Sporozoite_P67 0.003| Herpes_LMP2 0.063| PRK05325 0.098| PRK12678 | secA | Totivirus_coat |

Best

match to Length of First First Number

PRK Extent of best % Match residue of residue of of

database E value Match Score match match % identity length match sequence segments

4E-76 gnl|CDD|83603 279

trehalose-6-phosphate hydrolase. 562 551 32 102 2 17 1

0.68 gnl|CDD|73654 29.3

sec-independent translocase. 55 148 34 37 70 96 1

5E-12 gnl|CDD|83603 65.8

trehalose-6-phosphate hydrolase. 104 551 38 19 409 177 1





0.42

L-aspartate oxidase. gnl|CDD|76139 29.5 27 520 48 5 319 262 1

0.002 gnl|CDD|83003 37.2

cytoplasmic alpha-amylase. 315 487 22 65 94 1 1

0.72 gnl|CDD|77565 28.9

ferric iron-catecholate outer membrane transporter. 23 663 43 3 224 220 1









0.11 gnl|CDD|84229 31.1

transcription termination factor Rho. 143 683 17 21 182 12 1

0.45 gnl|CDD|82694

N-acetylmuramoyl-L-alanine amidase. 29.3 62 619 20 10 23 197 1

0.11 gnl|CDD|83729 31

anaerobic ribonucleotide reductase-activating protein. 73 155 27 47 10 168 1



0.83

hypothetical protein. gnl|CDD|83860 28.1 81 113 28 72 23 68 1

0.002 gnl|CDD|82694

N-acetylmuramoyl-L-alanine amidase. 36.6 110 619 20 18 7 1 2

0.002 gnl|CDD|83003

cytoplasmic alpha-amylase. 36.8 164 487 18 34 75 42 1









0.86

enoyl-CoA hydratase. gnl|CDD|81858 28.3 62 258 25 24 31 156 1

0.68 gnl|CDD|83914

ATP-dependent RNA helicase DeaD. 28.1 72 630 26 11 121 17 1





0.074

elongation factor P. gnl|CDD|81383 30.6 67 189 26 35 58 36 1









0.94 gnl|CDD|76008 26.8 47 834

bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon. 29 6 793 10 1





0.005

hypothetical protein. gnl|CDD|81524 33.6 49 405 32 12 52 26 2

0.0004

serine endoprotease. gnl|CDD|83609 37.7 58 476 37 12 288 24 2



0.003 gnl|CDD|84229

transcription termination factor Rho. 34.1 112 683 17 16 137 3 3

0.056 gnl|CDD|75248

8-amino-7-oxononanoate synthase. 29.9 71 370 26 19 84 6 1

0.18 gnl|CDD|84389

preprotein translocase subunit SecA. 28.5 28 862 42 3 634 27 1

0.12 gnl|CDD|83284 29.1 61

predicted propionyl-CoA synthetase with ATPase domain. 630 29 10 123 6 1









0.034

hypothetical protein. gnl|CDD|81524 30.6 45 405 28 11 52 4 3

Orientatio Best

n of match to Length of First First

assemble CP-PEP Extent of best % Match residue of residue of

d output database E value Match Score match match % identity length match sequence

FOR 0.00E+00

CPIJ016362-PA CPIJ016362-PA 1096 584 584 89 100 1 1

FOR 1.00E-141

CPIJ008900-PA CPIJ008900-PA 498 336 338 74 99 2 79

FOR 1.00E-150

CPIJ016362-PA CPIJ016362-PA 525 325 584 81 56 218 1

1.00E-165

CPIJ014551-PA CPIJ014551-PA 577 313 313 86 100 1 1

8.00E-49

CPIJ014551-PA CPIJ014551-PA 190 313 313 31 100 6 2

FOR 1.00E-173

CPIJ017793-PA CPIJ017793-PA 602 299 427 94 70 98 1

FOR 1.00E-161

CPIJ017521-PA CPIJ017521-PA 561 297 533 89 56 142 1

FOR 1.00E-119

CPIJ004231-PA CPIJ004231-PA 425 286 369 68 78 30 10

1.00E-150

CPIJ014551-PA CPIJ014551-PA 528 284 313 88 91 30 1

4.00E-38

CPIJ014551-PA CPIJ014551-PA 154 270 313 31 86 49 1

3.00E-88

CPIJ020192-PA CPIJ020192-PA 320 259 311 61 83 67 1

FOR 2.00E-91

CPIJ002646-PA CPIJ002646-PA 331 251 249 68 101 1 1

FOR 1.00E-118

CPIJ012373-PA CPIJ012373-PA 421 246 263 86 94 8 23

FOR 1.00E-115

CPIJ007741-PA CPIJ007741-PA 409 246 279 82 88 27 1

1.00E-109

CPIJ007742-PA CPIJ007742-PA 391 235 268 83 88 34 1

FOR 1.00E-133

CPIJ003384-PA CPIJ003384-PA 470 234 410 94 57 108 1

FOR 5.00E-81

CPIJ002046-PA CPIJ002046-PA 296 229 227 71 101 1 1

FOR 1.00E-120

CPIJ005064-PA CPIJ005064-PA 428 225 497 92 45 47 1

1.00E-110

CPIJ003615-PA CPIJ003615-PA 392 214 214 90 100 1 1

1.00E-113

CPIJ015714-PA CPIJ015714-PA 402 207 207 86 100 1 16

2.00E-14

CPIJ012060-PA CPIJ012060-PA 75.5 205 298 28 69 99 26

FOR 2.00E-16

CPIJ014551-PA CPIJ014551-PA 82 204 313 25 65 36 2

FOR 1.00E-81

CPIJ007742-PA CPIJ007742-PA 298 182 268 82 68 34 1

2.00E-99

CPIJ018300-PA CPIJ018300-PA 356 171 255 94 67 85 1

8.00E-84

CPIJ005738-PA CPIJ005738-PA 305 165 168 86 98 4 3

FOR 1.00E-74

CPIJ013702-PA CPIJ013702-PA 274 164 162 76 101 1 1

4.00E-70

CPIJ019052-PA CPIJ019052-PA 259 160 160 73 100 1 1

8.00E-50

CPIJ019040-PA CPIJ019040-PA 191 157 156 59 101 1 1

7.00E-83

CPIJ019051-PA CPIJ019051-PA 301 156 159 85 98 4 1

1.00E-60

CPIJ014547-PA CPIJ014547-PA 227 156 161 65 97 1 1

2.00E-59

CPIJ010787-PA CPIJ010787-PA 223 149 144 71 103 1 1

3.00E-81

CPIJ005450-PA CPIJ005450-PA 296 148 148 91 100 1 1

7.00E-77

CPIJ005064-PA CPIJ005064-PA 281 143 497 89 29 355 1

2.00E-74

CPIJ004029-PA CPIJ004029-PA 273 137 258 91 53 122 1

8.00E-72

CPIJ010517-PA CPIJ010517-PA 264 137 162 86 85 26 1

FOR 2.00E-55

CPIJ001841-PA CPIJ001841-PA 209 137 303 69 45 166 1

6.00E-36

CPIJ010792-PA CPIJ010792-PA 145 136 164 45 83 24 1

1.00E-34

CPIJ010792-PA CPIJ010792-PA 140 136 164 44 83 24 1

FOR 7.00E-10

CPIJ002236-PA CPIJ002236-PA 58.2 135 147 34 92 3 2

FOR 5.00E-37

CPIJ019291-PA CPIJ019291-PA 148 127 394 65 32 305 1

7.00E-59

CPIJ018872-PA CPIJ018872-PA 221 123 479 86 26 357 1

FOR 9.00E-12

CPIJ002236-PA CPIJ002236-PA 64.3 118 147 40 80 21 1

FOR 5.00E-29

CPIJ010792-PA CPIJ010792-PA 121 117 164 46 71 28 1

FOR 4.00E-48

CPIJ019050-PA CPIJ019050-PA 185 114 163 76 70 1 1

FOR 2.00E-61

CPIJ019874-PA CPIJ019874-PA 229 113 113 93 100 1 1

3.00E-39

CPIJ017729-PA CPIJ017729-PA 155 111 231 71 48 121 1

1.00E-48

CPIJ014952-PA CPIJ014952-PA 186 106 504 82 21 398 1

1.00E-17

CPIJ001263-PA CPIJ001263-PA 84.7 101 523 44 19 427 8

2.00E-03

CPIJ006741-PA CPIJ006741-PA 36.6 101 157 24 64 46 8

FOR 3.00E-10

CPIJ002236-PA CPIJ002236-PA 59.3 100 147 43 68 21 3

Best

Orientatio match to

Number n of AEGY- Length of First

of assemble PEP Extent of best % Match residue of

segments d output database E value Match Score match match % identity length match

1 FOR alpha-amylase 0.00E+00 AAEL009524-RA 899 580 579 73 100 1

1 FOR 6.00E-68 protein

conserved hypothetical AAEL004382-RA 254 400 396 39 101 33

1 FOR alpha-amylase1.00E-113 AAEL009524-RA 405 324 579 63 56 217

1 FOR 2.00E-47

D7 protein, putative AAEL006424-RA 185 322 321 33 100 6

1 FOR 3.00E-34

D7 protein, putative AAEL006424-RA 141 326 321 27 102 1

1 FOR 1.00E-152 AAEL002595-RA 533

serine protease 299 428 80 70 100

1 FOR alpha-amylase1.00E-128 AAEL006719-RA 452 297 737 70 40 346

1 FOR 1.00E-139 binding protein

gram-negative bacteria AAEL007064-RA 489 287 371 76 77 32

1 FOR 3.00E-40

D7 protein, putative AAEL006424-RA 161 294 321 32 92 28

1 FOR 3.00E-30

D7 protein, putative AAEL006424-RA 128 270 321 28 84 51

1 FOR 1.00E-43 protein

conserved hypothetical AAEL008619-RA 172 244 330 41 74 69

1 FOR 9.00E-32 protein

conserved hypothetical AAEL010235-RA 132 271 273 33 99 1

1 FOR 1.00E-100 AAEL000718-RA 360

virus-induced RNA, putative 266 268 68 99 1

1 FOR 9.00E-43 protein

conserved hypothetical AAEL007776-RA 169 255 275 35 93 24

1 FOR 2.00E-38 protein

conserved hypothetical AAEL007780-RA 154 240 275 34 87 37

1 FOR 1.00E-112 AAEL004092-RA 401

deoxyribonuclease I, putative 234 415 77 56 113

1 FOR 1.00E-18 protein

conserved hypothetical AAEL010228-RA 89 194 215 26 90 21

1 FOR alpha-amylase1.00E-102 AAEL008452-RA 367 225 495 76 45 47

1 FOR 5.00E-19

hypothetical protein AAEL013532-RB 90.1 143 220 34 65 78

1 FOR 2.00E-38 protein

conserved hypothetical AAEL002656-RA 154 199 206 40 97 23

1 FOR 9.20E-02

slender lobes, putative AAEL002774-RB 33.1 206 1239 20 17 73

1 FOR 3.00E-91

D7 protein, putative AAEL008620-RA 330 255 311 65 82 57

1 FOR 2.00E-30 protein

conserved hypothetical AAEL007780-RA 128 190 275 35 69 37

1 FOR 1.00E-61 AAEL003053-RF 231

allergen, putative 169 211 64 80 43

1 FOR 1.00E-12

hypothetical protein AAEL014259-RA 68.6 150 166 32 90 15

1 FOR 4.20E-01 AAEL004437-RA 30

dual-specificity protein phosphatase, putative 100 362 25 28 256

1 FOR coatomer 8.80E-01 AAEL013098-RA 28.9 54 1227 31 4 25

1 FOR 3.90E-01

hypothetical protein AAEL002679-RA 30 77 168 23 46 11

1 FOR 1.10E+00 protein

conserved hypothetical AAEL004863-RA 28.5 50 432 32 12 196

1 FOR 1.00E-04

D7 protein, putative AAEL002726-RA 41.6 88 227 26 39 77

1 FOR 6.00E-25 protein

conserved hypothetical AAEL004342-RA 108 130 140 38 93 8

1 FOR 2.00E-62

lysozyme P, putative AAEL003723-RA 233 136 148 76 92 13

1 FOR 5

alpha-amylase.00E-58 AAEL008452-RA 218 143 495 66 29 355

1 FOR venom allergen 2.00E-48 AAEL002693-RA 186 137 259 59 53 123

1 FOR 1.10E+00 AAEL000533-RA 28.1

antifreeze protein, putative 92 154 28 60 62

1 FOR 4.10E-01 AAEL000087-RA 29.6

macroglobulin/complement 41 888 34 5 499

1 FOR 2.00E-04 protein

conserved hypothetical AAEL004188-RA 40.4 120 564 33 21 422

1 FOR 8.00E-04 protein

conserved hypothetical AAEL004188-RA 38.5 123 564 33 22 422

5 FOR 4.00E-06 AAEL003603-RA 45.4

transcription factor, putative 97 293 36 33 104

1 FOR 2.00E-55

serine protease htra2 AAEL006373-RA 209 125 411 83 30 287

1 FOR 9.00E-08 protein

conserved hypothetical AAEL006351-RA 51.2 109 281 31 39 166

4 FOR 9.00E-08 AAEL005386-RA 50.8

collagen alpha chain, anopheles 119 1746 35 7 378

1 FOR 1.00E-02 protein

conserved hypothetical AAEL004188-RA 34.3 121 564 32 21 424

1 FOR 2.30E-01 protein

conserved hypothetical AAEL002123-RA 29.6 66 632 28 10 424

1 FOR 3.00E-52 domain protein 2 198

WAP four-disulfide coreAAEL011639-RA precursor, putative

115 115 79 100 1

1 FOR 2.00E-49 AAEL001178-RA 189

serine protease 104 247 79 42 144

1 FOR 4.00E-37 AAEL006121-RA 148

Trypsin, putative 104 398 64 26 294

1 FOR 5.00E-48

alkaline phosphatase AAEL000931-RA 185 146 562 62 26 414

1 FOR 2.00E-06 protein

conserved hypothetical AAEL008305-RA 47 64 95 34 67 31

4 FOR fibrillarin 4.00E-06 AAEL010248-RA 45.4 78 324 39 24 2

Best

First Number match to Length of First

residue of of AGPROT Extent of best % Match residue of

sequence segments database E value Match Score match match % identity length match

1 0.00E+00

1 AGAP002102-PA AGAP002102-PA 715 561 593 59 95 33

16 9.90E-02

1 AGAP008187-PA AGAP008187-PA 33.9 88 500 27 18 329

1 5.00E-87

1 AGAP002102-PA AGAP002102-PA 316 327 593 50 55 229

3 3.00E-45

1 AGAP008278-PA AGAP008278-PA 177 314 311 32 101 1

2 1.00E-37

1 AGAP008278-PA AGAP008278-PA 152 291 311 30 94 6

1 1.00E-114

1 AGAP011787-PA AGAP011787-PA 405 303 425 64 71 94

1 1.00E-113

1 AGAP006371-PA AGAP006371-PA 402 298 468 64 64 76

9 3.00E-87

1 AGAP002798-PA AGAP002798-PA 317 298 390 50 76 34

2 3.00E-42

1 AGAP008278-PA AGAP008278-PA 167 283 311 35 91 32

3 1.00E-32

1 AGAP008278-PA AGAP008278-PA 135 243 311 31 78 53

1 6.00E-11

1 AGAP007141-PA AGAP007141-PA 63.5 152 254 30 60 82

1 5.00E-07

1 AGAP009974-PA AGAP009974-PA 50.4 126 180 32 70 44

1 6.00E-78

1 AGAP009473-PA AGAP009473-PA 286 265 295 59 90 1

1 1.20E+00

1 AGAP006228-PA AGAP006228-PA 29.3 80 540 27 15 183

4 1.50E+00

1 AGAP010261-PA AGAP010261-PA 28.9 47 1158 36 4 253

1 5.00E-91

1 AGAP011046-PA AGAP011046-PA 329 233 422 65 55 122

40 3.00E-06

1 AGAP002456-PA AGAP002456-PA 47.8 92 950 25 10 10

1 3.00E-94

1 AGAP002317-PA AGAP002317-PA 340 223 515 72 43 50

71 4.00E-03

1 AGAP005300-PC AGAP005300-PC 37.4 69 681 37 10 156

27 5.00E-24

1 AGAP008782-PA AGAP008782-PA 106 201 217 30 93 30

13 3.00E-05

1 AGAP001989-PA AGAP001989-PA 44.7 190 257 21 74 61

1 3.00E-77

1 AGAP006278-PA AGAP006278-PA 283 261 320 55 82 64

4 1.10E+00

1 AGAP010261-PA AGAP010261-PA 28.9 47 1158 36 4 253

1 6.00E-29

1 AGAP006421-PA AGAP006421-PA 122 163 260 39 63 88

32 8.10E-01

1 AGAP010599-PA AGAP010599-PA 28.9 74 663 24 11 177

30 2.10E-01

1 AGAP004833-PA AGAP004833-PA 30.8 56 953 33 6 22

18 5.60E-01

1 AGAP001415-PA AGAP001415-PA 29.3 114 863 21 13 259

3 4.70E+00

1 AGAP003702-PA AGAP003702-PA 26.2 50 1370 32 4 1282

77 3.50E+00

1 AGAP004870-PA AGAP004870-PA 26.6 80 1328 23 6 1063

25 5.60E-01

1 AGAP008282-PA AGAP008282-PA 29.3 63 168 28 38 23

7 1.00E-09

1 AGAP010648-PA AGAP010648-PA 58.2 135 327 25 41 4

14 4.00E-42

1 AGAP007347-PA AGAP007347-PA 165 135 140 54 96 9

1 6.00E-57

1 AGAP002318-PA AGAP002318-PA 214 143 498 65 29 358

1 9.00E-38

1 AGAP006421-PA AGAP006421-PA 150 131 260 52 50 122

53 1.40E-01

1 AGAP002200-PA AGAP002200-PA 30.8 53 637 26 8 207

60 2.60E-01

2 AGAP011271-PA AGAP011271-PA 30 119 1278 21 9 821

3 2.00E+00

1 AGAP002655-PA AGAP002655-PA 26.9 37 763 29 5 225

3 1.50E+00

1 AGAP006838-PA AGAP006838-PA 27.3 62 138 27 45 10

20 6.00E-08

3 AGAP006504-PA AGAP006504-PA 51.2 143 173 35 83 1

1 6.00E-36

1 AGAP000240-PA AGAP000240-PA 144 103 440 66 23 338

16 7.10E-01

1 AGAP007269-PA AGAP007269-PA 28.1 43 488 32 9 258

1 4.00E-11

19 AGAP007349-PA AGAP007349-PA 61.6 120 1663 37 7 0

1 7.70E-01

1 AGAP009037-PA AGAP009037-PA 27.7 83 1095 28 8 601

24 5.90E-01

1 AGAP008782-PA AGAP008782-PA 28.1 35 217 34 16 112

1 1 2.00E-29

AGAP011460-PA AGAP011460-PA 122 114 109 50 105 1

1 1 3.00E-38

AGAP004552-PA AGAP004552-PA 152 94 282 65 33 188

1 1 6.00E-32

AGAP001707-PA AGAP001707-PA 130 96 563 61 17 165

2 1 4.00E-43

AGAP010596-PA AGAP010596-PA 169 114 574 68 20 423

31 1 3.60E-02

AGAP004367-PA AGAP004367-PA 32.3 74 2123 24 3 8

3 3 1.00E-09

AGAP006108-PA AGAP006108-PA 57 90 402 43 22 3

Clustered Clustered Clustered Clustered

at 30%- at 40%- at 50%- at 60%-

Sim- on Sim- on Sim- on Sim- on

First Number Clustered 50% of 50% of 50% of 50% of

residue of of by length - - length - - length - - length - -

sequence segments psiblast # seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs Cluster#

22 1 3 9 4 6 3 6 3 6 2

96 1 34 2 179 1 192 1 195 1 203

1 1 3 9 4 6 3 6 3 6 2

1 1 2 11 3 7 4 6 4 6 5

2 1 2 11 3 7 4 6 4 6 6

1 1 5 7 6 3 21 2 20 2 19

1 1 3 9 36 2 167 1 169 1 176

9 1 69 1 69 1 69 1 69 1 75

3 1 2 11 3 7 4 6 4 6 5

2 1 2 11 3 7 4 6 4 6 6

64 1 5 7 80 1 80 1 81 1 87

23 2 4 8 5 5 29 2 27 2 26

1 1 78 1 78 1 78 1 79 1 85

107 1 6 6 2 7 2 6 2 6 41

19 1 6 6 2 7 2 6 2 6 3

2 1 161 1 166 1 179 1 182 1 189

9 19 4 8 5 5 5 3 5 3 4

3 1 3 9 36 2 220 1 227 1 235

35 1 4 8 8 3 6 3 6 3 7

31 1 1 22 33 2 24 2 23 2 138

40 1 195 1 204 1 218 1 225 1 233

1 1 2 11 3 7 43 1 43 1 47

19 1 6 6 2 7 2 6 2 6 3

9 1 13 2 16 2 41 1 41 1 45

38 1 1 22 1 22 1 20 228 1 236

32 1 1 22 1 22 1 20 1 14 24

39 1 1 22 1 22 1 20 1 14 44

25 1 1 22 1 22 1 20 30 2 246

14 1 1 22 1 22 1 20 1 14 38

26 1 2 11 1 22 26 2 25 2 23

7 2 2 11 53 1 49 1 49 1 55

12 1 134 1 135 1 143 1 144 1 151

1 1 3 9 99 1 99 1 100 1 106

1 1 13 2 16 2 172 1 175 1 182

78 1 1 22 1 22 1 20 1 14 49

1 1 1 22 1 22 1 20 213 1 221

38 1 1 22 1 22 1 20 1 14 1

30 1 1 22 1 22 1 20 1 14 1

1 2 118 1 118 1 123 1 124 1 130

24 1 88 1 89 1 89 1 90 1 96

78 1 176 1 185 1 198 1 203 1 211

0 31 27 2 30 2 23 2 22 2 21

15 1 1 22 1 22 1 20 1 14 1

56 1 1 22 1 22 1 20 34 1 32

1 1 25 2 28 2 22 2 21 2 20

10 1 5 7 7 3 27 2 198 1 206

1 2 5 7 7 3 138 1 139 1 146

2 1 52 1 52 1 48 1 48 1 54

37 1 194 1 203 1 217 1 224 1 232

2 11 27 2 30 2 23 2 22 2 21

Clustered Clustered Clustered Clustered

at 70%- at 80%- at 90%- at 95%-

Sim- on Sim- on Sim- on Sim- on

50% of 50% of 50% of 50% of

length - - length - - length - - length - -

# seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs

6 2 6 2 5 4 3 10 2

1 207 1 208 1 216 1 220 1

6 2 6 98 1 99 1 100 1

3 5 3 5 3 147 1 150 1

3 6 3 6 3 16 2 13 2

2 15 2 15 2 13 2 90 1

1 180 1 180 1 186 1 190 1

1 78 1 77 1 78 1 78 1

3 5 3 5 3 15 2 144 1

3 6 3 6 3 175 1 179 1

1 90 1 89 1 90 1 91 1

2 21 2 21 2 18 2 221 1

1 88 1 87 1 88 1 88 1

1 36 1 35 1 31 1 28 1

5 3 5 3 4 2 4 1 4

1 193 1 194 1 201 1 205 1

3 4 3 4 3 3 3 5 2

1 241 1 242 1 253 1 260 1

3 7 3 7 3 5 3 3 3

1 141 1 141 1 144 1 147 1

1 239 1 240 1 251 1 258 1

1 46 1 45 1 43 1 41 1

5 3 5 193 1 199 1 203 1

1 42 1 41 1 39 1 36 1

1 242 1 243 1 254 1 261 1

2 19 2 19 2 17 2 14 2

1 41 1 40 1 38 1 35 1

1 252 1 253 1 264 1 271 1

1 33 1 32 1 28 1 25 1

2 155 1 155 1 160 1 164 1

1 56 1 55 1 54 1 52 1

1 154 1 154 1 159 1 163 1

1 109 1 109 1 110 1 111 1

1 186 1 186 1 192 1 196 1

1 48 1 47 1 46 1 44 1

1 225 1 226 1 235 1 241 1

8 1 7 1 7 6 2 4 2

8 1 7 1 7 1 4 2 3

1 133 1 133 1 136 1 138 1

1 99 1 99 1 100 1 101 1

1 215 1 216 1 224 1 230 1

2 17 2 17 2 126 1 128 1

8 1 7 1 7 45 1 43 1

1 27 1 26 1 22 1 18 1

2 16 2 16 2 14 2 12 2

1 210 1 211 1 219 1 224 1

1 149 1 149 1 154 1 158 1

1 55 1 54 1 53 1 51 1

1 237 1 238 1 249 1 256 1

2 17 2 17 2 119 1 120 1

No.

First Link to SigP Cleavage Mature potential

Seq name residue Seq size CDS Result Position MW pI MW pI glyc sites

Ctar-212 S 312 Ctar-212 29.888 4.42 133

Ctar-313 L 323 Ctar-313 36.324 5.97 1

Ctar-274 G 323 Ctar-274 37.479 5.14 0

Ctar-434 E 317 Ctar-434 34.577 4.88 0

Ctar-396 G 316 Ctar-396 33.631 4.81 0

Ctar-289 A 313 Ctar-289 35.782 8.53 1

Ctar-411 R 306 Ctar-411 32.419 5.07 3

Ctar-494 G 306 Ctar-494 33.213 6.49 3

Ctar-596 M 304 Ctar-596 SIG 19-20 35.368 5.52 33.217 5.4 0

Ctar-140 G 302 Ctar-140 33.917 5.17 1

Ctar-389 T 302 Ctar-389 34.254 8.52 0

Ctar-692 G 302 Ctar-692 31.581 7.79 0

Ctar-405 Y 300 Ctar-405 33.132 6.02 29

Ctar-386 K 300 Ctar-386 33.151 4.77 1

Ctar-401 L 299 Ctar-401 33.171 5.6 1

Ctar-312 T 298 Ctar-312 31.79 5.4 1

Ctar-507 R 310 Ctar-507 34.199 6.2 0

Ctar-272 A 295 Ctar-272 33.032 5.4 0

Ctar-607 G 291 Ctar-607 31.197 5.39 0

Ctar-267 M 281 Ctar-267 CYT 32.486 4.99 0

Ctar-364 M 279 Ctar-364 28.986 9.11 1

Ctar-357 E 279 Ctar-357 32.57 5.78 2

Ctar-257 D 273 Ctar-257 30.126 8.76 0

Ctar-315 A 270 Ctar-315 29.485 8.64 0

Ctar-354 E 268 Ctar-354 29.944 8.78 1

Ctar-380 M 267 Ctar-380 CYT 30.116 6.62 1

Ctar-349 Q 267 Ctar-349 29.251 5.99 0

Ctar-444 G 266 Ctar-444 28.551 6.46 3

Ctar-175 P 267 Ctar-175 29.516 4.39 1

Ctar-281 S 265 Ctar-281 30.213 4.89 0

Ctar-469 E 264 Ctar-469 29.967 6.85 0

Ctar-211 E 260 Ctar-211 24.582 4.16 101

Ctar-325 S 257 Ctar-325 29.422 8.34 0

Ctar-325 S 257 Ctar-325 29.436 8.34 0

Ctar-193 S 257 Ctar-193 28.198 5.02 1

Ctar-420 T 269 Ctar-420 31.367 5.86 1

Ctar-589 V 253 Ctar-589 27.798 4.69 10

Ctar-426 P 247 Ctar-426 26.297 8.34 13

Ctar-459 T 244 Ctar-459 27.158 5.47 11

Ctar-441 S 245 Ctar-441 26.918 9.72 11

Ctar-550 Q 239 Ctar-550 25.797 7.8 0

Ctar-117 G 232 Ctar-117 24.69 5.24 12

Ctar-641 K 236 Ctar-641 26.703 7.82 0

Ctar-287 P 235 Ctar-287 24.752 9.24 3

Ctar-258 G 234 Ctar-258 27.033 9.03 0

Ctar-321 I 232 Ctar-321 25.6 5.61 0

Ctar-553 G 227 Ctar-553 25.253 9.18 0

Ctar-292 M 226 Ctar-292 CYT 25.76 6.87 0

Ctar-574 D 226 Ctar-574 26.856 9.93 0

Ctar-253 M 226 Ctar-253 CYT 24.654 4.55 0

Ctar-125 M 224 Ctar-125 SIG 19-20 25.294 5.34 23.354 5.24 0

Ctar-61 R 239 Ctar-61 26.534 9.96 0

Ctar-139 S 221 Ctar-139 24.695 5.31 0

Ctar-98 A 221 Ctar-98 23.984 9.3 2

Ctar-394 M 218 Ctar-394 CYT 25.305 10.12 0

Ctar-446 A 218 Ctar-446 24.093 5.55 0

Ctar-248 M 216 Ctar-248 SIG 17-18 23.96 4.91 22.252 4.91 0

Ctar-330 N 212 Ctar-330 24.536 8.85 0

Ctar-515 D 212 Ctar-515 24.218 5.8 0

Ctar-294 R 213 Ctar-294 23.679 5.99 0

Ctar-235 M 209 Ctar-235 CYT 22.803 7.61 1

Ctar-699 R 208 Ctar-699 24.298 9.03 0

Ctar-245 E 208 Ctar-245 22.953 9.1 1

Ctar-217 K 208 Ctar-217 22.547 11.24 1

Ctar-255 K 230 Ctar-255 25.78 10.73 1

Ctar-337 E 202 Ctar-337 24.269 8.85 0

Ctar-120 L 202 Ctar-120 22.197 10.65 0

Ctar-566 E 199 Ctar-566 22.905 6.48 0

Ctar-323 A 198 Ctar-323 20.976 4.38 8

Ctar-304 P 301 Ctar-304 34.07 6.15 0

Ctar-73 R 195 Ctar-73 22.052 10.49 0

Ctar-331 R 193 Ctar-331 22.094 9.41 1

Ctar-367 A 193 Ctar-367 21.953 9.1 1

Ctar-296 F 302 Ctar-296 34.828 5.53 1

Ctar-227 K 186 Ctar-227 20.629 8.43 5

Ctar-796 C 187 Ctar-796 19.402 8.36 0

Ctar-797 S 231 Ctar-797 25.944 9.93 0

Ctar-455 P 184 Ctar-455 21.198 4.95 0

Ctar-276 R 180 Ctar-276 20.026 4.86 4

Ctar-517 S 177 Ctar-517 20.586 4.82 1

Ctar-491 M 177 Ctar-491 CYT 21.162 10.67 0

Ctar-571 R 175 Ctar-571 19.325 6.58 0

Ctar-608 G 173 Ctar-608 19.352 4.95 3

Ctar-234 R 174 Ctar-234 19.985 5.87 1

Ctar-92 A 172 Ctar-92 20.198 10.5 0

Ctar-795 G 170 Ctar-795 18.296 6.47 19

Ctar-382 E 170 Ctar-382 19.106 5.43 2

Ctar-562 A 169 Ctar-562 18.526 6.96 0

Ctar-251 G 168 Ctar-251 19.59 5.1 0

Ctar-97 L 165 Ctar-97 17.842 9.32 3

Ctar-792 L 164 Ctar-792 19.271 10.17 0

Ctar-279 K 162 Ctar-279 18.049 6.65 0

Ctar-362 Q 162 Ctar-362 18.849 6.24 0

Ctar-228 P 162 Ctar-228 17.725 6.59 4

Ctar-329 N 161 Ctar-329 18.624 5.11 0

Ctar-369 M 157 Ctar-369 CYT 17.457 7.64 3

Ctar-400 K 169 Ctar-400 18.575 7.81 0

Ctar-213 V 159 Ctar-213 18.144 5.26 0

Ctar-123 M 156 Ctar-123 CYT 17.264 10.08 0

Ctar-303 F 156 Ctar-303 18.541 5.53 0

Ctar-283 F 155 Ctar-283 15.933 8.66 0

Ctar-604 N 155 Ctar-604 16.971 9.41 0

Ctar-215 M 154 Ctar-215 CYT 16.851 9.9 1

Ctar-83 V 154 Ctar-83 17.089 8.33 1

Ctar-145 R 153 Ctar-145 17.023 5.9 0

Ctar-153 M 143 Ctar-153 CYT 16.958 11.66 0

Ctar-501 I 149 Ctar-501 16.475 6.1 0

Ctar-327 F 148 Ctar-327 -1 15.869 9.84 1

Ctar-324 A 148 Ctar-324 16.214 4.37 11

Ctar-256 K 190 Ctar-256 22.452 6.17 0

Ctar-359 W 147 Ctar-359 16.818 4.89 0

Ctar-290 E 146 Ctar-290 16.325 9.3 1

Ctar-322 L 145 Ctar-322 15-16 16.345 9.61 14.666 9.93 0

Ctar-206 R 145 Ctar-206 17.506 11.34 1

Ctar-481 N 145 Ctar-481 16.079 9.06 1

Ctar-318 G 143 Ctar-318 15.907 10.04 2

Ctar-185 P 143 Ctar-185 16.153 4.54 7

Ctar-231 Y 143 Ctar-231 16.35 7.14 1

Ctar-91 M 138 Ctar-91 SIG 24-25 14.905 4.73 12.319 4.7 5

Ctar-102 K 140 Ctar-102 16.154 10.3 0

Ctar-116 G 136 Ctar-116 14.218 8.93 7

Ctar-435 E 135 Ctar-435 15.282 6.06 0

Ctar-376 G 133 Ctar-376 15.319 9.07 2

Ctar-383 G 133 Ctar-383 14.847 4.74 0

Ctar-99 M 132 Ctar-99 CYT 14.377 10.06 1

Ctar-310 V 132 Ctar-310 14.986 4.49 0

Ctar-320 M 131 Ctar-320 CYT 14.878 4.13 0

Ctar-169 K 130 Ctar-169 15.138 9.93 0

OC-365 A 128 OC-365 14.554 4.86 0

Ctar-190 E 131 Ctar-190 14.588 9.62 1

Ctar-786 T 126 Ctar-786 14.613 6.77 1

Ctar-271 Q 125 Ctar-271 13.824 4.92 0

Ctar-222 G 123 Ctar-222 14.317 5.08 0

Ctar-391 N 123 Ctar-391 13.113 4.53 0

Ctar-340 R 122 Ctar-340 13.802 8.66 0

Ctar-273 R 120 Ctar-273 12.554 9.37 13

Ctar-619 E 118 Ctar-619 12.951 5.39 0

Ctar-275 G 116 Ctar-275 12.914 9.91 0

Ctar-403 K 116 Ctar-403 13.513 9.37 1

Ctar-343 D 115 Ctar-343 13.29 6.56 0

Ctar-326 G 115 Ctar-326 12.957 5.21 0

Ctar-288 K 115 Ctar-288 13.065 7.07 1

Ctar-379 C 185 Ctar-379 20.236 6.92 2

Ctar-395 T 113 Ctar-395 12.591 5.58 3

Ctar-485 F 112 Ctar-485 12.645 5.87 0

Ctar-250 A 196 Ctar-250 22.548 9.2 6

Ctar-606 S 111 Ctar-606 12.603 9.43 0

Ctar-350 Y 109 Ctar-350 11.845 5.47 1

Ctar-599 G 109 Ctar-599 11.716 8.11 0

Ctar-402 Q 107 Ctar-402 12.608 7.04 2

Ctar-291 M 107 Ctar-291 CYT 12.575 10.09 0

Ctar-499 K 107 Ctar-499 11.573 8.62 1

Ctar-277 F 107 Ctar-277 12.499 4.66 0

Ctar-223 T 106 Ctar-223 12.598 10.14 3

Ctar-418 G 106 Ctar-418 11.641 6.45 0

Ctar-314 E 106 Ctar-314 11.982 5.41 0

Ctar-375 R 106 Ctar-375 12.124 10.15 0

Ctar-480 A 106 Ctar-480 11.968 9.47 0

Ctar-496 E 105 Ctar-496 11.796 6.32 0

Ctar-534 A 104 Ctar-534 11.882 11.51 0

Ctar-225 R 104 Ctar-225 11.99 10.47 1

Ctar-264 T 291 Ctar-264 32.393 9.61 15

Ctar-232 P 103 Ctar-232 11.722 9.96 0

Ctar-597 Y 103 Ctar-597 11.672 8.08 0

Ctar-676 A 99 Ctar-676 10.577 9.64 0

Ctar-238 M 102 Ctar-238 SIG 18-19 11.597 6.49 9.619 5.6 1

Ctar-309 M 102 Ctar-309 SIG 20-21 11.388 8.74 8.929 6.8 0

Ctar-184 I 101 Ctar-184 11.457 4.4 10

Ctar-70 M 101 Ctar-70 CYT 11.551 9.51 0

% Stop

Percent Percent Percent TMHMM Predicted membran Descripti codon?

Ser+Thr Gly Pro result Lenght helices e % outside % inside on (*)

42.9 11 8.2 312 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o aggrecan core protein - fragment

9.1 6.7 5.2 323 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o 26S proteasome regulatory complex ATPase RP

9.8 7.9 2.4 323 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o starch branching enzyme - fragment

12.1 7.8 4.7 ExpAA=75.93 First60=0.00 PredHel=4 Topology=i128-150o155-177i201-223o299-316i

317 4 26.2 25.6 48.3 calcium-transporting atpase sarcoplasmic/endop

12.1 10.9 4.7 316 0

ExpAA=0.11 First60=0.02 PredHel=0 Topology=o ATP-citrate synthase - fragment

14.2 4.7 5 313 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o conserved hypothetical protein - fragment

12.2 11.3 5.1 306 0

ExpAA=0.10 First60=0.00 PredHel=0 Topology=o ATP synthase beta subunit - fragment

10.6 9 4.8 306 0

ExpAA=0.22 First60=0.00 PredHel=0 Topology=o malic enzyme - fragment

12.3 3.9 6.1 ExpAA=21.81 First60=21.561

304 7.2 90.5

PredHel=1 Topology=i7-29o 2.3 UDP-glucuronosyltransferase - truncated at 3 pr

14.3 6.2 4.9 302 0

ExpAA=2.32 First60=0.00 PredHel=0 Topology=o actin 1D - fragment

11.7 7.2 3.6 302 0

ExpAA=10.35 First60=0.00 PredHel=0 Topology=o recessive suppressor of secretory defect - fragm

9.4 11.4 5.2 302 0

ExpAA=0.16 First60=0.01 PredHel=0 Topology=o *

3-ketoacyl-CoA thiolase - truncated at 5 prime

17.7 4.6 3.9 300 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

vitellogenin - truncated at 5 prime

9.8 6.9 4.9 300 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o 78 kDa glucose-regulated protein - fragment

8.6 7.6 6.6 299 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o elongation factor - fragment

13.2 7.9 4.3 298 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o apolipophorin fragment

9.2 7.9 4.1 310 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o elongation factor Tu - fragment

6 9 3.3 295 0

ExpAA=0.15 First60=0.00 PredHel=0 Topology=o histidyl-tRNA synthetase - fragment

12.5 9.5 3.4 291 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o aminomethyltransferase, mitochondrial - fragme

9.1 2.8 1.7 281 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o coatomer subunit epsilon - truncated at 3 prime

17 8.1 2.8 279 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ubiquinol-cytochrome c reductase complex core

10.2 3.9 1.8 279 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o Puromycin-sensitive aminopeptidase - fragment

12.3 6.1 5.4 273 0

ExpAA=1.40 First60=0.79 PredHel=0 Topology=o fatty acid synthase S-acetyltransferase - fragme

11.7 8.4 4 270 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o *

3-hydroxyacyl-coa dehyrogenase - truncated at

10.3 8.1 3.3 268 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o conserved hypothetical protein - fragment

8.9 7 4.4 267 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o 26S protease regulatory subunit 8 - truncated at

12.2 6.3 4.1 267 0

ExpAA=14.05 First60=0.00 PredHel=0 Topology=o *

purine biosynthesis protein 6, pur6 - truncated a

13 10.7 7.8 266 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o conserved hypothetical protein - fragment

12.5 10.3 4.1 267 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o *

membrane protease 3 - truncated at 5 prime

11.9 2.6 2.2 265 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

9.3 6 4.5 264 0

ExpAA=0.45 First60=0.41 PredHel=0 Topology=o 2-oxoisovalerate *dehydrogenase subunit alpha,

38.3 14.8 10.6 260 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o aggrecan core protein - fragment

12.6 6.9 3.8 257 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o *

Endoribonuclease XendoU - truncated at 5 prim

12.6 6.9 3.8 257 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o *

Endoribonuclease XendoU - truncated at 5 prim

9.2 6.5 7.7 257 0

ExpAA=0.40 First60=0.02 PredHel=0 Topology=o *

40S ribosomal protein SA - truncated at 5 prime

11.4 5.1 4 269 0

ExpAA=2.20 First60=0.01 PredHel=0 Topology=o *

tyrosine kinase receptor - truncated at 5 prime

15.6 8.6 5.4 253

ExpAA=22.24 First60=0.02 PredHel=1 Topology=o167-189i

1 8.7 66 *

25.3 translocon-associated protein subunit alpha - tru

16.3 7.6 7.6 247 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o *

slender lobes - truncated at 5 prime

14.1 7.7 9.3 244 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o *

polymerase delta-interacting protein - truncated

18.1 7.6 3.2 245 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o restin - truncated*at 5 prime

9.5 8.6 4.1 239 0

ExpAA=0.69 First60=0.00 PredHel=0 Topology=o *

Acetyl-CoA acetyltransferase - truncated at 5 pr

14 10.6 6.8 232 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

10.8 5.4 3.8 236 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

mitochondrial ribosomal protein, L46 - truncated

10.5 7.9 5.9 235 0

ExpAA=0.23 First60=0.01 PredHel=0 Topology=o *

mitochondrial malate dehydrogenase - truncated

10.5 4.6 0.8 234

ExpAA=21.78 First60=12.540PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

9.7 6.8 2.1 232 0

ExpAA=0.03 First60=0.01 PredHel=0 Topology=o *

galactokinase - truncated at 5 prime

8.7 7.8 2.6 227 0

ExpAA=8.98 First60=8.98 PredHel=0 Topology=o *

60S ribosomal protein L5 - truncated at 5 prime

8.3 4.3 1.7 226 0

ExpAA=1.14 First60=0.00 PredHel=0 Topology=o *

vacuolar ATP synthase subunit e

11.7 5.2 3.9 226 0

ExpAA=0.20 First60=0.00 PredHel=0 Topology=o *

ribosome production factor 1 - truncated at 5 pri

9.1 6.5 4.3 226 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o elongation factor *1-beta

10.5 6.1 0.9 224 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o *

ferritin light chain-like

11.9 9.1 5.3 239 0

ExpAA=0.52 First60=0.01 PredHel=0 Topology=o *

40S ribosomal protein S2 - truncated at 5 prime

15.1 6.7 4.4 221 0

ExpAA=0.76 First60=0.06 PredHel=0 Topology=o *

actin - truncated at 5 prime

10.2 10.2 5.8 221 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

40S ribosomal protein S3 - truncated at 5 prime

5.4 8.1 5.4 218 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

60S ribosomal protein L10

14 5.4 3.2 218 0

ExpAA=0.09 First60=0.07 PredHel=0 Topology=o *

ATP synthase gamma chain, mitochondrial - tru

13.2 7.3 4.5 216 0

ExpAA=0.09 First60=0.08 PredHel=0 Topology=o conserved hypothetical protein - truncated at 3 p

13 5.6 1.9 ExpAA=88.06 First60=15.294

212 40.1 27.4 32.5 Predicted G-protein

PredHel=4 Topology=i46-68o99-121i134-156o183-202i * coupled receptor - truncated

9.3 4.2 3.2 212 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

saposin - truncated at 5 prime

6.5 9.7 4.6 213 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o hydroxypyruvate *isomerase - truncated at 5 prim

15.6 7.5 0.9 209 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o guanine nucleotide-binding protein subunit beta

8.5 3.8 4.3 208 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o Nuclear transport* receptor LGL2 (importin beta s

10 6.6 7.1 208

ExpAA=41.38 First60=2.84 PredHel=2 Topology=i110-129o161-180i Mitochondrial phosphate carrier protein - truncat

2 18.3 15.4 66.3 *

9 5.7 4.3 208 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ribosomal protein* L23a - truncated at 5 prime

9.4 3.8 4.3 230 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ribosomal protein S6 - fragment

9.8 3.9 2.9 202 0

ExpAA=0.05 First60=0.05 PredHel=0 Topology=o *

eukaryotic translation initiation factor 3 subunit 9

7.3 13.2 5.9 202 0

ExpAA=0.13 First60=0.13 PredHel=0 Topology=o *

60S ribosomal protein L8 - truncated at 5 prime

10.4 4.5 5.4 199 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o *

Cell cycle-associated protein - truncated at 5 pri

14.4 6 7 ExpAA=86.47 First60=41.844

198 41.9 7.6 50.5 monocarboxylate* transporter - truncated at 5 pri

PredHel=4 Topology=i9-26o36-58i70-92o97-119i

10.8 6.2 4.9 301

ExpAA=99.43 First60=0.13 PredHel=5 Topology=o65-87i140-162o191-210i230-252o262-279i

5 33.9 34.6 *

31.6 na+/k+ atpase alpha subunit - truncated at 5 prim

6.6 7.6 2.5 195 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o ribosomal protein* S8 - truncated at 5 prime

6.1 0.5 5.1 193 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

coiled-coil domain-containing protein 124 - trunc

9.2 7.1 5.6 193 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

6.5 3.9 5.2 302 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o nucleolar GTP-binding protein - fragment

3.7 4.8 7.9 186 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o translation initiation factor if-2 - fragment

14.2 11.1 1.1 187 0

ExpAA=0.05 First60=0.04 PredHel=0 Topology=o ubiquinol-cytochrome c reductase complex core

15.7 8.1 4.3 231 0

ExpAA=1.98 First60=0.00 PredHel=0 Topology=o *

hypothetical conserved protein - truncated at 5 p

8.6 5.3 1.6 184 0

ExpAA=0.23 First60=0.00 PredHel=0 Topology=o *

alpha-1,2-mannosyltransferase alg11 - truncated

10.9 8.2 5.5 180 0

ExpAA=0.05 First60=0.00 PredHel=0 Topology=o *

disulfide-isomerase A6 - truncated at 5 prime

10 5 2.8 177 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

10 3.9 4.4 177 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o *

60S ribosomal protein L18a

10.7 9 1.7 175

ExpAA=13.94 First60=13.920PredHel=0 Topology=o *

hexokinase - truncated at 5 prime

18.2 6.3 2.3 173 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

9.6 5.1 4 174 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

mitochondrial ribosomal protein, S35 - truncated

6.3 5.7 5.1 172 0

ExpAA=0.05 First60=0.02 PredHel=0 Topology=o ribosomal protein* L7 - truncated at 5 prime

22.5 7.5 5.8 170 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

hypothetical conserved protein - truncated at 5 p

12.1 8.1 6.4 170

ExpAA=20.88 First60=1.12 PredHel=1 Topology=i150-169o

1 11.2 0.6 *

88.2 fasciclin - truncated at 5 prime

7.6 6.4 9.3 169 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

tRNA-binding protein - truncated at 5 prime

16.4 4.7 4.7 168 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

9.5 10.1 6.5 165 0

ExpAA=0.03 First60=0.02 PredHel=0 Topology=o *

40S ribosomal protein S3 - truncated at 5 prime

9.6 3.6 6 164 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

40S ribosomal protein S7 - truncated at 5 prime

9.7 6.1 3.6 162 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o isochorismatase * domain-containing protein 2, m

4.8 4.2 1.2 162 0

ExpAA=6.04 First60=6.04 PredHel=0 Topology=o *

ATP synthase B chain, mitochondrial - truncated

13.9 10.3 5.5 ExpAA=61.36 First60=3.47 PredHel=3 Topology=o59-81i88-107o120-137i

162 3 35.8 44.4 19.8 Golgi-associated*protein/Nedd4 WW domain-bin

10.4 5.5 4.9 161 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

clathrin light chain - truncated at 5 prime

15 5 5.6 157 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o conserved hypothetical protein - truncated at 3 p

12.8 12.2 3.5 169 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

peptidyl-prolyl cis-trans isomerase f, ppif - trunca

6.8 4.3 . 159 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

LRR Toll - truncated at 5 prime

8.8 7.5 3.8 156 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o ribosomal protein* S19

12.6 5.7 3.8 156 0

ExpAA=0.03 First60=0.01 PredHel=0 Topology=o elongation factor *1-gamma - truncated at 5 prim

11.4 13.3 0.6 ExpAA=91.27 First60=43.844

155 56.8 27.7 15.5 vacuolar ATP *

PredHel=4 Topology=o4-26i38-60o90-112i124-146o synthase 21 kDa proteolipid subun

12 9.5 4.4 155 0

ExpAA=0.49 First60=0.37 PredHel=0 Topology=i *

UDP-glucose pyrophosphorylase - truncated at

16.6 4.5 4.5 ExpAA=66.65 First60=21.033

154 39.6 24.7 35.7 conserved insect*protein

PredHel=3 Topology=o25-47i60-77o90-112i

10.8 7 4.5 154 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

40S ribosomal protein S3A - truncated at 5 prim

10.3 5.8 1.9 153 0

ExpAA=0.05 First60=0.05 PredHel=0 Topology=o *

kynurenine formamidase - truncated at 5 prime

8.2 4.8 1.4 143 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

60S ribosomal protein L36

7.2 9.2 1.3 149 0

ExpAA=0.11 First60=0.10 PredHel=0 Topology=o *

threonine dehydratase/deaminase - truncated at

9.9 13.2 4 148

ExpAA=69.44 First60=42.164PredHel=4 Topology=i5-27o40-62i69-86o90-107i

52.7 11.5 35.8 mitochondrial NADH:ubiquinone oxidoreductase

*

15.2 5.3 9.3 148 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

6.7 3.1 5.7 190 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

Chondroitin 6-sulfotransferase - truncated at 5 p

9.3 4 4.7 147 0

ExpAA=0.03 First60=0.03 PredHel=0 Topology=o *

Ras-related GTPase - truncated at 5 prime

10.7 8.1 6.7 146 0

ExpAA=8.33 First60=0.06 PredHel=0 Topology=o -

Citrate synthase * truncated at 5 prime

7.4 11.5 6.8 145

ExpAA=31.73 First60=24.401PredHel=1 Topology=o44-66i

15.2 30.3 *

54.5 Predicted membrane protein - truncated at 5 prim

5.4 4.1 0.7 145 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i ribosomal protein* L19 - truncated at 5 prime

7.4 6.1 6.1 145 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

Long-chain acyl-CoA synthetases - truncated at

12.3 8.2 2.1 143 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o *

60S ribosomal protein L3 - truncated at 5 prime

11 3.4 11 143 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

12.3 4.1 4.1 143 0

ExpAA=0.13 First60=0.13 PredHel=0 Topology=i *

conserved hypothetical protein - truncated at 5 p

9.3 5 10 ExpAA=44.12 First60=39.892

138 30.4 10.9 *

PredHel=2 Topology=i7-27o42-64i 58.7 hypothetical conserved secreted protein

5.6 9.2 2.1 140 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ribosomal protein* S4 - truncated at 5 prime

13.8 10.1 8 136 0

ExpAA=0.08 First60=0.07 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

9.5 8 5.1 135 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=o peroxiredoxin-4 -*truncated at 5 prime

8.9 5.9 6.7 133 0

ExpAA=0.02 First60=0.00 PredHel=0 Topology=o 5'-AMP-activated*protein kinase catalytic subuni

9.6 6.7 0.7 133 0

ExpAA=0.27 First60=0.21 PredHel=0 Topology=o *

annexin x - truncated at 5 prime

9.7 9 3.7 132 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

40S ribosomal protein S30

6 4.5 3.7 132 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

heat shock cognate 70 - truncated at 5 prime

6.8 7.5 4.5 131 0

ExpAA=0.21 First60=0.00 PredHel=0 Topology=o *

DNA-directed RNA polymeraseI

8.3 6.8 2.3 130 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o ribosomal protein* S27a - truncated at 5 prime

7.7 9.2 3.8 128 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

vitronectin - truncated at 5 prime

12 6.8 . 131 0

ExpAA=0.77 First60=0.44 PredHel=0 Topology=i *

conserved hypothetical protein - truncated at 5 p

5.5 2.3 4.7 126 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

AH receptor-interacting protein - truncated at 5 p

11 9.4 2.4 125 0

ExpAA=0.02 First60=0.02 PredHel=0 Topology=i *

cathepsin l - truncated at 5 prime

5.6 4.8 4 123 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

ATP-binding cassette transporter - truncated at

9.6 8.8 3.2 123 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=i *

anamorsin - truncated at 5 prime

15.3 3.2 2.4 122 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

16.4 12.3 5.7 120 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

15 5.8 1.7 118

ExpAA=11.97 First60=11.960PredHel=0 Topology=o *

glycerol-3-phosphate acyltransferase - truncated

15.3 7.6 3.4 116 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

Clathrin-associated protein medium chain - trunc

13.6 2.5 5.1 116 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i *

vitellogenin C1 - truncated at 5 prime

9.4 3.4 6.8 115 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

6 6.8 3.4 115 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

ATP synthase beta subunit - truncated at 5 prim

12.8 5.1 6.8 115 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=i *

E3 ubiquitin ligase - truncated at 5 prime

10.6 6.4 9.6 185 0

ExpAA=0.01 First60=0.00 PredHel=0 Topology=o *

6-phosphogluconolactonase - truncated at 5 prim

15.7 3.5 4.3 113 0

ExpAA=0.03 First60=0.00 PredHel=0 Topology=o *

eukaryotic translation initiation factor 3 subunit 5

14 6.1 4.4 112 0

ExpAA=0.42 First60=0.29 PredHel=0 Topology=o *

glutathione-s-transferase theta, gst - truncated a

6 3.5 20.1 196 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

12.4 2.7 3.5 111 0

ExpAA=13.10 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

6.3 9.9 7.2 109 0

ExpAA=5.70 First60=4.15 PredHel=0 Topology=i *

amidase - truncated at 5 prime

9.9 11.7 3.6 109

ExpAA=38.24 First60=17.312PredHel=2 Topology=o28-45i84-106o

35.8 28.4 35.8 *

Predicted membrane protein - truncated at 5 prim

5.5 1.8 3.7 107 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

transcription initiation factor TFIID subunit 12 - tr

2.8 11 8.3 107

ExpAA=21.63 First60=0.00 PredHel=1 Topology=o74-96i

1 20.6 69.2 10.3 *

mitochondrial ATP synthase F chain

10.1 13.8 3.7 107 0

ExpAA=3.87 First60=3.86 PredHel=0 Topology=o *

proteasome subunit beta type 6 - truncated at 5

5.5 3.7 1.8 107 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

prefoldin - truncated at 5 prime

11.1 2.8 5.6 106 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i *

60S ribosomal protein L31 - truncated at 5 prime

12 9.3 6.5 106 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

glutamate carboxypeptidase - truncated at 5 prim

7.4 9.3 6.5 106 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

2.8 8.3 4.6 106 0

ExpAA=0.05 First60=0.01 PredHel=0 Topology=o *

60S ribosomal protein L15 - truncated at 5 prime

12 10.2 3.7 106 0

ExpAA=14.54 First60=6.15 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

16.8 6.5 0.9 105 0

ExpAA=0.02 First60=0.01 PredHel=0 Topology=o *

dynein light chain, putative - truncated at 5 prime

8.5 10.4 2.8 104 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

60S ribosomal protein L35a - truncated at 5 prim

7.5 8.5 8.5 104

ExpAA=19.54 First60=19.541PredHel=1 Topology=o31-53i

21.2 29.8 49 *

NADH:ubiquinone oxidoreductase, NDUFB6/B1

8.1 15.9 6.4 291 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o conserved hypothetical protein - fragment

6.7 7.6 4.8 103 0

ExpAA=0.01 First60=0.01 PredHel=0 Topology=o ribosomal protein* S16 - truncated at 5 prime

12.4 3.8 1.9 103 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i *

60S ribosomal protein L9 - truncated at 5 prime

8.9 6.9 4 99 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=i *

ezrin-radixin-moesin-binding phosphoprotein 50

8.7 8.7 6.7 102 0

ExpAA=8.98 First60=4.79 PredHel=0 Topology=o *

mitochondrial NADH-ubiquinone oxidoreductase

12.5 11.5 1 102

ExpAA=19.50 First60=19.501PredHel=1 Topology=o5-24i

18.6 4.9 76.5 *

conserved hypothetical protein

13.6 3.9 12.6 101 0

ExpAA=0.00 First60=0.00 PredHel=0 Topology=o *

conserved hypothetical protein - truncated at 5 p

7.8 1.9 6.8 101

ExpAA=43.94 First60=27.272PredHel=2 Topology=i21-40o55-77i 44.6

40.6 14.9 *

hypothetical protein

Best

match to Length of First

Salivary SAL-DIP Extent of best % Match residue of

Class motifs database E value Match Score match match % identity length match

extmat 0.008

putative salivary proteingi|38350685 32.7 77 228 33 34 19

prot 0.0 gi|94469214

26S proteasome regulatory complex ATPase RPT4 632 323 393 98 82 68

met carb 0.98 gi|37778968

thrombostasin precursor 25.8 36 309 41 12 20

st uncharacterized patterngi|94468672

0.19 |

Aegyptin mosquito stringent transmembrane protein 28.1 41 275 26 15 21

met en synthetase alpha subunit 43.9

succinyl-CoA 3E-006 gi|94468890 143 327 27 44 175

tm unknown 1.6 gi|56199436 25 57 230 28 25 154

met en 1E-156 gi|94468834

F0F1-type ATP synthase beta subunit 543 306 504 92 61 67

met en malic enzyme1E-163 gi|94469192 565 306 574 89 53 179

met carb 3E-033 gi|94468600

UDP-glucuronosyl transferase 133 284 521 31 55 25

cs actin 1E-174 gi|94468486 603 302 376 98 80 56

st 0.24

putative alpha-amylase gi|4887104 27.7 62 497 27 12 106

met int 1E-146 gi|94469330

acetyl-CoA acetyltransferase 509 302 398 83 76 97

tr serine protease0.53 gi|56199542 26.6 74 296 25 25 66

pm 1E-158

heat shock cognate 70 gi|94468818 548 300 655 92 46 344

ps 0.69 gi|94468442

mitochondrial ATP synthase alpha subunit26.2 72 551 31 13 480

tr Ag9 protein 1.5 gi|17932668 25 69 392 26 18 289

ps 2E-040 gi|56199452

elongation factor 1 alpha 157 328 463 32 71 3

ps 1.2 gi|18568334

putative prophenoloxidase activating protein 25.4 38 413 26 9 102

met aa putative serpin 0.66 gi|18568304 26.2 37 418 43 9 333

pe 1.8 gi|94468330

PA26-T3 nuclear protein-like protein 24.6 59 349 23 17 106

met en gSG1b protein 2.4 gi|13537664 24.3 33 385 45 9 61

met aa eukaryotic translation initiation factor 3 subunit

0.37 degenerate

Culex salivary 16.8 kDa family-less gi|45934563pattern | 26.9 112 304 25 37 167

met lipid 5.2 gi|94469214

26S proteasome regulatory complex ATPase RPT450

23.1 393 30 13 15

met en dynactin 0.12 gi|94469352 28.5 66 381 36 17 139

met en 0.092 gi|94469366

nuclear distribution protein NUDC 28.9 32 325 40 10 12

prot 7E-045 gi|94468994

26S proteasome regulatory chain 4 172 227 438 40 52 63

met nuc 3.0 gi|8745398

putative adenosine deaminase 23.9 28 508 46 6 408

ps 0.35

putative salivary mucin gi|38350653 26.9 62 260 35 24 59

pm serine protease5E-055 gi|94468616 205 272 362 40 75 96

uc 6E-016 LIG-1

membrane glycoproteingi|94468954 75.9 293 508 25 58 126

met lipid protein gi|61744155

39 kDa salivary 1.7 24.6 50 375 32 13 27

extmat secreted mucin 0.040 gi|94468738 30 121 184 22 66 57

met secondary protein kinase 1 0.74 gi|56199500 25.8 81 227 20 36 64

met secondary protein kinase 1 0.74 gi|56199500 25.8 81 227 20 36 64

ps 1E-109 gi|94468996

40S ribosomal protein SA 387 257 288 75 89 36

st 7E-013 gi|94468458

glycogen synthase kinase 3 65.9 242 491 25 49 95

pe 0.32 gi|94469132

activating transcription factor 26.9 52 405 26 13 296

pm 1.2

unknown salivary protein gi|51557820 25 66 158 28 42 58

tr 0.91 gi|5817646

salivary gland growth factor-2 25.4 39 506 28 8 215

cs 0.41

putative salivary proteingi|56417428 26.6 15 97 60 15 26

met lipid 6E-024 gi|94469330

acetyl-CoA acetyltransferase 102 213 398 34 54 182

uc 1.9

35.5 kDa salivary protein gi|77696455 24.3 20 332 50 6 100

ps 0.060

ribosomal protein S16 gi|56417546 29.3 102 172 26 59 49

met en protein SP56

30 kDa salivary0.30 gi|74486573 26.9 80 283 23 28 83

uc 0.86 gi|94468338

hypothetical MTT-rich mucin 25.4 89 159 25 56 10

met carb 2.5 gi|94468480

peptide methionine sulfoxide reductase 23.9 66 235 27 28 111

ps 1E-118 gi|94469072

60S ribosomal protein L5 417 227 297 90 76 71

ps synthase subunit E

vacuolar ATP 2E-084 gi|94469084 303 226 226 71 100 1

ps 3E-028 gi|94469098 116

U3 small nucleolar ribonucleoprotein component 223 313 31 71 81

pm 7E-093

elongation factor 1 betagi|45934557 331 222 224 76 99 4

tr 1E-023

ferritin light chain-like gi|56199456 101 247 236 31 105 1

met en 1E-125

ribosomal protein S2 gi|94468354 439 240 275 92 87 36

cs actin 1E-126 gi|94468486 440 221 376 98 59 156

ps 4.0 gi|16225974

long form D7clu2 salivary protein 23.1 54 315 31 17 177

ps 1E-121

ribosomal protein L10 gi|94468384 424 216 219 91 99 1

met en 1.7 gi|94468948 24.3

polyQ domain-containing hypothetical conserved protein39 484 30 8 12

pm SGS4 0.45 gi|54066728 26.2 106 3398 26 3 2819

st serine/threonine1.3 gi|94468946 24.6

specific protein phosphatase PP1 catalytic subunit

43 327 27 13 34

met lipid 2.8

40S ribosomal protein S3A gi|94468430 23.5 75 270 26 28 163

met carb 0.34 gi|94469106

syndecan binding protein 26.6 41 333 31 12 109

st 3E-009 C receptor

activated protein kinasegi|94468452 53.5 164 311 23 53 15

met carb 0.56 gi|94469174

replication factor C 25.8 66 358 27 18 228

tr phosphate carrier protein 371

mitochondrial 1E-105 gi|94468998 208 350 88 59 71

cs Rab-protein 23 gi|94469302 20.4 21 415 38 5 172

met en 1E-037

ribosomal protein S6 gi|56199524 147 97 332 77 29 124

pm 0.53 gi|76446589

42 kDa yellow-related salivary protein SP03 25.8 54 388 33 14 264

ps 1E-104 gi|94468892

60S ribosomal protein L2/L8 368 178 261 100 68 63

nr SGS5 2.6 gi|54066769 23.5 95 3361 25 3 632

tr 0.89 gi|56417500

putative 30 kDa allergen-like protein 30k-1 25 14 210 64 7 58

tr 1.2 gi|94468708

phosphatidylinositol transfer protein SEC14 25.4 78 327 24 24 135

ps 6E-095

ribosomal protein S8 gi|56417536 337 180 206 92 87 27

uc conserved protein3E-039 gi|114864586 152 122 198 69 62 54

uc protein

gSG1b salivary0.86 gi|114865039 25 43 384 34 11 202

tm putative 34 kDa2.0 gi|18568296

secreted protein 24.6 35 316 37 11 205

ps

met en 6.9 gi|94468876

RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I 35

21.9 28 398 complex 7 61

ps putative salivary1.9 gi|56417508

secreted 30 kDa allergen-like protein 30k-5 204

24.3 42 30 21 71

pm 0.055 gi|94469224

prophenoloxidase activator 28.9 20 374 60 5 321

pm 1E-095 gi|94469058

protein disulfide isomerase 340 174 437 92 40 264

uc 2E-083 gi|94468962

unknown conserved protein 299 171 326 83 52 154

ps 1E-100 gi|56417534

60S ribosomal protein L18a 356 177 177 97 100 1

met en 2E-004 gi|51557687

ribosomal protein subunit 3 36.6 69 265 31 26 182

ps 0.087 gi|18568300

putative secreted protein 28.1 38 580 39 7 123

ps 0.15

hypothetical protein gi|94468724 27.3 79 254 18 31 175

ps 6E-096

ribosomal protein L7 gi|94468794 340 172 263 94 65 35

uc 0.42 gi|4539761

salivary peroxidase 25.8 77 591 31 13 59

extmat 5E-053 gi|94468630

probable membrane protein 198 168 375 60 45 221

ps 0

salivary apyrase.54 gi|56417436 25.4 29 564 37 5 317

pm 0.41 gi|94468990

flavin-containing monooxygenase 25.8 66 428 28 15 114

ps 1.2 gi|16225974

long form D7clu2 salivary protein 24.3 54 315 31 17 177

ps 1.5 gi|94469338

translation initiation factor 2B beta subunit23.9 38 353 34 11 84

uc 4.3 gi|114864694

short form D7 salivary protein 3 22.3 71 169 28 42 66

met en 0.18 gi|16225974

long form D7clu2 salivary protein 26.9 66 315 28 21 145

pm 7.4 hyp37.7

homolog of an. stephensi hyp37.3 putative secreted17

21.6 267 35 6 8

pe protein

29 kDa salivary0.39 gi|76589378 25.8 39 272 38 14 95

met aa 0.097

hypothetical protein gi|94469120 27.7 97 289 25 34 23

pm cyclophylin 1E-094 gi|94468418 336 164 164 95 100 1

st 0.020 gi|94468628

prefoldin subunit 6 30 96 127 27 76 20

ps 7E-074

ribosomal protein S19 gi|56417548 267 156 156 86 100 1

ps 3E-087 gi|94468844

elongation factor 1-gamma 311 156 433 89 36 278

tr/vatpase 3E-015 subunit

vacuolar atpase 16kDa gi|56199558 72.4 147 155 29 95 20

met carb glyoxylase 2.3 gi|94468788 23.1 54 294 25 18 1

uc 7E-066 gi|94469228

conserved insect protein 240 152 150 80 101 1

ps 5E-080 gi|94468430

40S ribosomal protein S3A 287 154 270 90 57 117

met aa 1E-053 gi|94468714

kynurenine formamidase 200 149 305 66 49 154

ps 1E-052 gi|94468922

60S ribosomal protein L36 196 99 113 97 88 15

met aa member

NICE-3 family 0.053 gi|94468778 28.5 48 290 35 17 1

met en 1E-055 gi|94469134 206

putative mitochondrial NADH-ubiquinone oxidoreductase 147 167 68 88 18

uc 0.34 gi|94468662

bacteria-responsive protein 1 AgBR1 25.8 51 439 31 12 40

extmat 0.22 gi|94468936

phosphoglycerate dehydrogenase 26.9 86 332 22 26 120

pe 3E-016

RAB family GTPase gi|94469128 75.9 109 215 39 51 65

met en SGS1 0.56 gi|66828491 25 30 3060 36 1 2783

ucm derlin 1 2E-058 gi|94469198 215 128 254 82 50 131

ps 1E-063

ribosomal protein L19 gi|94468808 233 145 204 81 71 60

met lipid 0.95 protein L52

mitochondrial ribosomalgi|94469356 24.3 27 129 44 21 101

ps 4E-070

ribosomal protein L3 gi|94468802 254 128 415 96 31 273

uc 71 kDa salivary 2.7protein gi|42491539 22.7 40 627 22 6 28

uc 1E-074

RAB family GTPase gi|94469128 270 143 215 94 67 73

uc 0.52 gi|94468710

histidine triad family zinc-binding protein 25 21 157 47 13 30

ps 1E-068

ribosomal protein S4 gi|94468470 249 128 195 99 66 56

uc 0.86 gi|77696455

35.5 kDa salivary protein 24.3 20 332 50 6 100

met ox 0.17 protein L49

mitochondrial ribosomalgi|94469056 26.6 29 185 44 16 88

st SGS5 0.074 gi|54066769 27.7 97 3361 29 3 980

extmat annexin 1E-061 gi|94468734 226 133 321 84 41 23

ps 0.025 gi|16074119

anopheles stephensi ubiquitin 29.3 83 128 33 65 1

pm 4E-059

heat shock cognate 70 gi|94468818 218 132 655 84 20 53

met aa 43 kDa salivary 4.0protein gi|77696451 21.9 35 397 37 9 135

prot 1E-051

ribosomal protein S27a gi|56417532 192 130 156 74 83 27

extmat 9E-18 sal_met_prot 80.5

truncated matrix metalloproteinase 1 - missing amino and carboxy terminal 36

118 465 - 25 271

uc salivary protein 2E-12 gSG5 63.2 127 332 25 38 200

pm 0.001 gi|94468750

FKBP-type peptidyl-prolyl cis-trans isomerase33.5 100 285 23 35 179

pm cathepsin L 8E-011 gi|56199438 57.4 105 331 29 32 223

tr 3.6

beta3-glucuronyltransferasegi|94468702 21.9 16 320 62 5 221

nr serine/threonine23 gi|94468946 19.2

specific protein phosphatase PP1 catalytic subunit

14 327 35 4 23

uc 0.064 LIG-1

membrane glycoproteingi|94468954 27.7 55 508 25 11 399

uc 30 kDa protein 0.11 gi|18389879 26.9 62 182 25 34 80

met lipid 0.52 gi|51557806

unknown salivary protein 24.6 43 157 32 27 72

pe actin 0.10 gi|94468486 26.9 113 376 20 30 246

tr 0.85

salivary gland protein gi|71389019 23.9 21 240 47 9 183

uc chloride channel 0.64 gi|94468636 24.3 69 391 20 18 47

met en 1E-059 gi|94468834

F0F1-type ATP synthase beta subunit 219 115 504 97 23 390

prot 0.026 gi|51557675

putative hyaluronoglucosaminidase 28.9 61 160 31 38 24

met carb RAS small GTPase 0.62 gi|94469286 25.4 32 217 34 15 2

ps 5E-051 gi|94468862 190

eukaryotic translation initiation factor 3 subunit 5 epsilon-like protein

113 287 85 39 175

pe 0.60 gi|42491533

37.2 kDa salivary protein 24.3 52 350 21 15 195

tm 2.6 protein L49

mitochondrial ribosomalgi|94469056 23.5 47 185 31 25 79

ps nucleosidase

salivary purine0.031 gi|21654712 28.5 45 338 42 13 47

ps 1.3 gi|94468582

20S proteasome regulatory subunit beta type PSMB3/PUP3 205

23.1 43 37 21 76

ucm 2.2

ribosomal protein L9 gi|56199512 22.3 47 194 25 24 52

tm 6.1 gi|5817646

salivary gland growth factor-2 20.8 25 506 28 5 469

met en ATP synthase F chain

mitochondrial 8E-064 gi|94468562 233 107 107 95 100 1

prot 5E-040 gi|94469190 154

proteasome subunit beta type 6 precursor-like protein

92 228 79 40 123

pm 0.55 gi|18568312

putative calreticulin 24.3 41 407 36 10 363

ps 9E-057 gi|56417558

60S ribosomal protein L31 209 106 124 97 85 19

met aa 2.7 gi|94468620

PAN/APPLE-like domain-containing protein 21.9 15 482 53 3 21

uc 2.1 hyp55.3

putative 55.3 salivary protein 22.3 40 513 27 8 214

ps 2E-056 gi|56417552

60S ribosomal protein L27a 208 106 149 89 71 44

met aa 2.1

fatty acyl-CoA elongasegi|94468340 22.3 20 358 40 6 64

cs antigen 5 family protein 122.3

putative salivary2.0 gi|38350629 62 255 27 24 150

ps 3E-047

ribosomal protein L35 gi|56199508 177 104 160 75 65 57

met en aquaporin 2 1.5 gi|94468982 22.7 37 264 32 14 199

uc 0.003 gi|94469038

reverse transcriptase-like protein 33.9 49 268 34 18 84

ps 1E-043

ribosomal protein S16 gi|56417546 166 84 172 97 49 65

ps 8E-052

ribosomal protein L9 gi|94468812 192 103 190 94 54 88

met aa 0.056 protein

histone H1 gamma-like gi|56684621 27.3 71 279 32 25 13

met en NADH-ubiquinone oxidoreductase AGGG subunit

mitochondrial 7E-048 gi|94468762 179 100 100 83 100 1

uc 0.046

ribosomal protein L4 gi|94469276 27.7 47 431 34 11 49

uc 16 gi|94468824

polyadenylate-binding protein 19.2 11 628 72 2 249

ps mucin gi|56417398

putative salivary1.4 22.7 19 295 47 6 273

Best

match to

First NR Length of First First

residue of protein Extent of best % Match residue of residue of

sequence database E value Match Score match match % identity length match sequence

14 5E-096

aggrecan core protein gi|170050268 354 339 2531 59 13 0 0

1 regulatory subunit S10B 632

26S protease 1E-179 gi|170034396 [Culex quinquefasciatus] 393

323 98 82 68 1

43 0.0 gi|170039584 663

deltamethrin resistance-associated NYD-GBE [Culex quinquefasciatus]

323 689 95 47 289 1

235 1E-178 gi|170066650 626

calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type [Culex 97

317 995 32 626 1

1 0.0

ATP-citrate synthase gi|170029202 636 316 1096 98 29 651 1

4 1E-168 protein [Culex 595

conserved hypothetical gi|170035122 quinquefasciatus] 314 557 92 56 108 1

1 beta subunit [Aedes aegypti]

ATP synthase1E-164 gi|157136033 581 306 504 97 61 67 1

1 [Culex gi|170052885

malic enzyme1E-173 quinquefasciatus] 611 306 653 97 47 258 1

21 1E-156 gi|170028271 553

UDP-glucuronosyltransferase 1-1 [Culex quinquefasciatus]305 521 88 59 1 1

1 similar RE12057p isoform605

PREDICTED:1E-171 to gi|156554898 2 [Nasonia302

vitripennis] 376 99 80 56 1

61 1E-171 secretory defect 604 302

recessive suppressor ofgi|170051617 [Culex quinquefasciatus]594 97 51 239 1

1 1E-162 [Culex quinquefasciatus]

3-ketoacyl-CoA thiolasegi|170032282 575 302 398 96 76 97 1

38 1

vitellogenin C2 E-159 gi|54289295 563 300 2042 90 15 305 1

1 1E-166 gi|170034715 588 300

78 kDa glucose-regulated protein [Culex quinquefasciatus] 657 99 46 345 1

9 1E-172 gi|170029844

elongation factor 2 608 299 1031 98 29 545 1

41 1E-164 gi|170043254

apolipophorins [Culex quinquefasciatus] 580 298 3324 96 9 2863 1

29 1E-167

elongation factor Tu gi|170047901 590 295 462 100 64 38 16

188 1E-160 gi|170062845 569

histidyl-tRNA synthetase [Culex quinquefasciatus] 295 521 96 57 29 1

48 1E-156 gi|170061082 552

aminomethyltransferase, mitochondrial [Culex quinquefasciatus] 413

291 94 70 93 1

128 1E-155 gi|170061951 551

coatomer subunit epsilon [Culex quinquefasciatus] 281 305 97 92 1 1

110 1E-148 reductase complex528 protein [Culex quinquefasciatus]

ubiquinol-cytochrome c gi|170052262 core 279 439 95 64 1 1

44 1E-139 gi|170029683 498

aminopeptidase 2, mitochondrial [Culex quinquefasciatus]279 900 86 31 516 1

172 1E-142 gi|170038418 508

fatty acid synthase S-acetyltransferase [Culex quinquefasciatus] 2419

273 94 11 2129 1

48 1E-147 gi|170041182 524

3-hydroxyacyl-coa dehyrogenase [Culex quinquefasciatus] 270 305 97 89 36 1

84 1E-118 protein [Culex 427

conserved hypothetical gi|170065429 quinquefasciatus] 268 564 83 48 234 1

21 regulatory subunit 8 [Culex quinquefasciatus]

26S protease 1E-145 gi|170048670 519 267 402 99 66 1 1

161 1E-146 gi|170045976 520 267

purine biosynthesis protein 6, pur6 [Culex quinquefasciatus] 429 96 62 163 1

153 1E-146 protein [Culex 521

conserved hypothetical gi|170052147 quinquefasciatus] 267 1332 95 20 932 1

1 1E-146

mast cell protease 3 gi|170042338 520 266 288 90 92 23 1

1 1E-119 protein [Culex 431

conserved hypothetical gi|170065519 quinquefasciatus] 265 344 81 77 81 1

222 1E-145 gi|170053106 518 264

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [Culex 438 94 60 175 1

25 3E-087

aggrecan core protein gi|170050268 325 260 2531 65 10 0 0

14 1E-143 gi|170057617

endoU protein [Culex quinquefasciatus] 509 258 556 96 46 299 1

14 1E-143 gi|170057617

endoU protein [Culex quinquefasciatus] 509 258 556 96 46 299 1

1 1E-134 gi|170059457 479

40S ribosomal protein SA [Culex quinquefasciatus] 258 282 93 91 36 1

17 1E-152 [Aedes aegypti] 542

tyrosine kinase receptorgi|157110899 269 706 97 38 438 1

204 1E-135 gi|170067248 483 249

translocon-associated protein subunit alpha [Culex quinquefasciatus] 291 97 86 42 1

49 [Culex gi|170035484

slender lobes 1E-109 quinquefasciatus] 397 249 1194 87 21 953 3

105 1E-133 gi|170055415 478

polymerase delta-interacting protein 2 [Culex quinquefasciatus] 381

245 93 64 137 1

194 1E-119 gi|170037680

restin [Culex quinquefasciatus] 429 245 410 90 60 88 1

2 1E-134 gi|170067602 479 239

trifunctional enzyme beta subunit [Culex quinquefasciatus] 467 99 51 229 1

191 1E-114 protein [Culex 414

conserved hypothetical gi|170038261 quinquefasciatus] 237 252 90 94 17 1

108 ribosomal protein, L46 425 236

mitochondrial 1E-117 gi|170058857[Culex quinquefasciatus] 272 91 87 37 1

51 malate gi|170044455 448

mitochondrial 1E-124 dehydrogenase 2 [Culex quinquefasciatus] 337

235 97 70 103 1

34 1E-128 protein [Culex 461

conserved hypothetical gi|170037702 quinquefasciatus] 234 417 96 56 184 1

80 [Culex gi|170059813

galactokinase1E-112 quinquefasciatus] 407 232 385 87 60 154 1

1 1E-126 gi|170049217 455

60S ribosomal protein L5 [Culex quinquefasciatus] 227 297 98 76 71 1

1 synthase subunit e [Culex 419

vacuolar ATP 1E-116 gi|170042855 quinquefasciatus] 226 226 96 100 1 1

1 1E-126 gi|170046389 454

ribosome production factor 1 [Culex quinquefasciatus] 226 365 96 62 140 1

5 1E-117 [Culex quinquefasciatus]

elongation factor 1-betagi|170039062 424 226 225 95 100 1 1

1 1E-121 gi|170035687

ferritin light-chain 437 223 223 97 100 1 1

1 1E-132 gi|157125338

40S ribosomal protein S2 [Aedes aegypti] 474 240 275 99 87 36 1

1 similar RE12057p isoform444

PREDICTED:1E-123 to gi|156554902 3 221 341 99 65 121 1

58 1E-120 gi|170057463 435

40S ribosomal protein S3 [Culex quinquefasciatus] 221 250 99 88 30 1

1 1E-124 gi|170068369 447

60S ribosomal protein L10 [Culex quinquefasciatus] 218 218 97 100 1 1

81 gamma gi|170030340 391 218

ATP synthase1E-107 chain, mitochondrial [Culex quinquefasciatus] 297 90 73 80 1

26 1E-107 protein [Culex 389

conserved hypothetical gi|170042988 quinquefasciatus] 216 261 87 83 1 1

8 1E-117 gi|170069402

GPR89A [Culex quinquefasciatus] 424 212 450 98 47 239 1

60 1E-118 gi|170057908

saposin [Culex quinquefasciatus] 426 212 1017 95 21 456 1

106 1E-105 gi|170042214 384

hydroxypyruvate isomerase [Culex quinquefasciatus] 212 265 86 80 57 1

46 1E-116 gi|170042647 beta 209

guanine nucleotide-binding protein subunit421 1 [Culex quinquefasciatus]

340 98 61 1 1

82 1E-116 gi|170031163

importin [Culex quinquefasciatus] 419 208 990 98 21 782 1

1 quinquefasciatus]

PfmpC [Culex1E-114 gi|170055171 414 208 353 97 59 146 1

187 1E-100 [Culex quinquefasciatus]

ribosomal protein L23a gi|170027935 366 208 247 93 84 40 1

1 2E-096 gi|157103329

ribosomal protein S6 [Aedes aegypti] 354 232 346 83 67 118 1

113 1E-113 gi|170031950 412 202

eukaryotic translation initiation factor 3 subunit 9 [Culex quinquefasciatus]

688 99 29 487 1

4 1E-113 gi|170028086 410

60S ribosomal protein L8 [Culex quinquefasciatus] 199 261 100 76 63 4

5 1E-113 gi|170047541

maintenance of ploidy protein mob1 [Culex410 199

quinquefasciatus] 218 97 91 20 1

142 1E-103 gi|170033018 376

monocarboxylate transporter [Culex quinquefasciatus] 198 802 96 25 605 1

10 1E-169 gi|157131369

na+/k+ atpase alpha subunit [Aedes aegypti] 597 301 1001 96 30 701 1

16 1E-105 gi|170052425 384

40S ribosomal protein S8 [Culex quinquefasciatus] 195 206 99 95 12 1

60 6E-094 gi|170037438 346

coiled-coil domain-containing protein 124 [Culex quinquefasciatus]211

193 92 91 18 1

76 4E-096 protein [Culex 353

conserved hypothetical gi|170052108 quinquefasciatus] 193 679 91 28 490 1

69 1E-153 gi|157124441

nucleolar GTP-binding protein [Aedes aegypti] 543 302 652 90 46 272 1

1E-081 gi|170061650 305

translation initiation factor if-2 [Culex quinquefasciatus]191 1022 85 19 152 1

138 9E-094 reductase complex345 protein [Culex quinquefasciatus]

ubiquinol-cytochrome c gi|170052262 core 187 439 90 43 187 1

3 quinquefasciatus]

gryzun [Culex5E-091 gi|170061675 337 185 1353 88 14 1093 1

106 3E-099 gi|170064341 363

alpha-1,2-mannosyltransferase alg11 [Culex quinquefasciatus] 481

184 97 38 298 1

7 2E-096 gi|170041921

disulfide-isomerase A6 [Culex quinquefasciatus]354 183 436 95 42 254 1

5 9E-090 protein [Culex 332

conserved hypothetical gi|170051464 quinquefasciatus] 178 292 92 61 115 1

1 9E-098 gi|157167176

60S ribosomal protein L18a [Aedes aegypti] 358 177 177 98 100 1 1

102 9E-095 gi|170045020

hexokinase [Culex quinquefasciatus] 348 175 449 98 39 275 1

98 1E-086 protein [Culex 321

conserved hypothetical gi|170073899 quinquefasciatus] 174 266 93 65 95 1

45 ribosomal protein, S35 321

mitochondrial 1E-086 gi|170036917 [Culex quinquefasciatus] 332

174 89 52 159 1

1 5E-095 gi|170047762 349

60S ribosomal protein L7 [Culex quinquefasciatus] 172 266 97 65 95 1

57 2E-071 gi|170051642

ZNF403 [Culex quinquefasciatus] 270 172 619 80 28 449 1

3 3E-084 gi|170037711

fasciclin [Culex quinquefasciatus] 313 170 365 89 47 199 1

105 2E-088 gi|170039763 327

multisynthetase complex auxiliary component p43 [Culex quinquefasciatus] 95

169 320 53 152 1

63 9E-094 protein [Culex 345

conserved hypothetical gi|170053579 quinquefasciatus] 168 218 98 77 51 1

2 3E-089 gi|170057463 329

40S ribosomal protein S3 [Culex quinquefasciatus] 165 250 99 66 86 1

112 1E-087 protein [Culex 324

conserved hypothetical gi|170040756 quinquefasciatus] 164 192 98 85 29 1

70 3E-083 gi|170037388 310 163

isochorismatase domain-containing protein 2, mitochondrial [Culex 201 95 81 39 1

6 B chain, gi|170039307 318

ATP synthase1E-085 mitochondrial [Culex quinquefasciatus] 238

162 97 68 77 1

120 1E-087 gi|170028084

NEDD4 family-interacting protein 1 [Culex 324 162

quinquefasciatus] 229 96 71 69 1

116 2E-087 gi|170066890

clathrin light chain 323 161 240 96 67 80 1

62 6E-064 protein [Culex 245

conserved hypothetical gi|170035599 quinquefasciatus] 161 512 81 31 1 1

6 cis-trans isomerase f, 337

peptidyl-prolyl2E-091 gi|157130325ppif [Aedes aegypti] 169 206 94 82 40 1

18 2E-052 gi|170037196

LRR Toll [Culex quinquefasciatus] 207 158 311 68 51 153 1

1 protein gi|170036432 308

40s ribosomal6E-083 s19 [Culex quinquefasciatus] 156 156 100 100 1 1

1 6E-088 gi|170060430 325

elongation factor 1-gamma [Culex quinquefasciatus] 156 430 95 36 275 1

2 synthase 21 kDa proteolipid 298

vacuolar ATP 1E-079 gi|170037112 155

subunit [Culex quinquefasciatus]

208 99 75 54 1

48 4E-082 gi|157110519 306

utp-glucose-1-phosphate uridylyltransferase 2 [Aedes 155 aegypti] 513 98 30 359 1

1 2E-074 gi|170049035 280

conserved insect protein [Culex quinquefasciatus] 155 155 93 100 1 1

1 2E-082 gi|170045145 307

40S ribosomal protein S3a [Culex quinquefasciatus] 154 376 98 41 223 1

1 7E-076 gi|170029822 285

kynurenine formamidase [Culex quinquefasciatus] 153 307 92 50 155 1

1 3E-049 gi|157103325 196

ribosomal protein L36, putative [Aedes aegypti] 99 113 97 88 15 1

32 6E-078 gi|170050264 292

threonine dehydratase/deaminase [Culex quinquefasciatus] 149 469 97 32 321 1

1 NADH:ubiquinone oxidoreductase B14.7148

mitochondrial 4E-074 gi|170050968 279 subunit [Culex

165 91 90 18 1

13 2E-061 protein [Culex 237

conserved hypothetical gi|170046784 quinquefasciatus] 148 194 79 76 51 1

59 AGAP005721-PA 8E-010 gi|158294651 66.6 208 400 21 52 195 1

1 5E-082 gi|170046123 305

ras-related protein Rab-7 [Culex quinquefasciatus] 147 208 99 71 62 1

89 AGAP012048-PA 2E-079 gi|158300600 296 146 466 97 31 321 1

18 7E-076 gi|170054332

derlin-2.1 [Culex quinquefasciatus] 285 146 260 94 56 115 1

1 5E-077 gi|170058304

ribosomal protein L19 [Culex quinquefasciatus]289 145 204 100 71 60 1

84 4E-076 protein [Culex 286

conserved hypothetical gi|170050090 quinquefasciatus] 145 645 97 22 501 1

1 1E-075 gi|170041842 284

60S ribosomal protein L3 [Culex quinquefasciatus] 143 452 98 32 310 1

3 3E-073 protein [Culex 276

conserved hypothetical gi|170028023 quinquefasciatus] 143 458 97 31 316 1

1 8E-072 protein [Culex 271

conserved hypothetical gi|170035713 quinquefasciatus] 143 215 95 67 73 1

83 1E-070 protein [Culex 268

conserved hypothetical gi|170037843 quinquefasciatus] 142 142 95 100 1 1

1 2E-071 gi|157123910

40S ribosomal protein S9 [Aedes aegypti] 270 140 195 97 72 56 1

95 2E-066 protein [Culex 254

conserved hypothetical gi|170038261 quinquefasciatus] 136 252 93 54 118 1

110 peroxiredoxin-4 2E-074 gi|170051146 280 135 252 99 54 118 1

1 8E-072 gi|170033124 271

5'-AMP-activated protein kinase catalytic subunit alpha-2 [Culex 547

133 98 24 415 1

1 5E-064 gi|170044825

annexin x [Culex quinquefasciatus] 246 133 321 94 41 34 1

1 9E-068 gi|170062090 258

40S ribosomal protein S30 [Culex quinquefasciatus] 132 132 98 100 1 1

1 3E-068 gi|170034715 259

78 kDa glucose-regulated protein [Culex quinquefasciatus] 132 657 97 20 526 1

85 RNA polymeraseI [Culex 265

DNA-directed 6E-070 gi|170068328 quinquefasciatus] 131 131 98 100 1 1

1 7E-071 gi|157136377 268

ubiquitin (ribosomal protein L40) [Aedes aegypti] 130 156 100 83 27 1

1 3E-064 gi|170063963

vitronectin [Culex quinquefasciatus] 246 128 488 89 26 361 1

1 6E-054 protein [Culex 212

conserved hypothetical gi|170030700 quinquefasciatus] 127 346 81 37 212 1

27 6E-064 protein [Culex 245

AH receptor-interacting gi|170069601 quinquefasciatus] 124 319 97 39 196 3

20 1E-068 gi|170064305

cathepsin l [Culex quinquefasciatus] 261 124 547 96 23 423 1

58 6E-061 gi|170037877 235

ATP-binding cassette transporter [Culex quinquefasciatus] 123 999 95 12 570 1

107 3E-062 gi|170046630

anamorsin [Culex quinquefasciatus] 239 123 261 94 47 139 1

51 1E-045 protein [Culex 184

conserved hypothetical gi|170034629 quinquefasciatus] 123 355 80 35 234 1

43 4E-051 protein [Culex 203

conserved hypothetical gi|170053221 quinquefasciatus] 120 1348 88 9 1222 1

39 1E-056 gi|170030668 221

glycerol-3-phosphate acyltransferase [Culex quinquefasciatus] 872

118 94 14 755 1

1 subunit gi|170047645 228

AP-2 complex8E-059 mu [Culex quinquefasciatus] 116 301 98 39 186 1

1 4E-057 gi|170049661

vitellogenin-A1 [Culex quinquefasciatus] 223 116 2111 90 5 1996 1

23 5E-062 protein [Culex 239

conserved hypothetical gi|170028299 quinquefasciatus] 115 287 100 40 173 1

1 beta subunit [Aedes aegypti]

ATP synthase5E-056 gi|157136033 219 115 504 97 23 390 1

12 2E-061 gi|170037607

LD06566p [Culex quinquefasciatus] 237 115 1010 96 11 896 1

116 5E-081 gi|157103954

6-phosphogluconolactonase [Aedes aegypti] 303 184 251 80 73 68 1

1 4E-054 gi|170055997 213 113

eukaryotic translation initiation factor 3 subunit 5 [Culex quinquefasciatus]

287 97 39 175 1

17 5E-053 gi|170068194 quinquefasciatus]

glutathione-s-transferase theta, gst [Culex 209 112 219 90 51 108 1

145 4E-076 gi|157109694 286

hypothetical protein AaeL_AAEL005358 [Aedes aegypti] 202 387 73 52 191 1

28 1E-037 protein [Culex 158

conserved hypothetical gi|170034398 quinquefasciatus] 111 225 70 49 115 1

5 4E-056 gi|170066943

amidase [Culex quinquefasciatus] 219 109 538 97 20 430 1

58 2E-055 19 [Culex quinquefasciatus] 109

transmembrane protein gi|170049236 217 332 94 33 224 1

49 7E-055 gi|170053104 215 107

transcription initiation factor TFIID subunit 12 [Culex quinquefasciatus]

176 100 61 70 1

1 ATP synthase F chain 239

mitochondrial 6E-062 gi|170037788[Culex quinquefasciatus]107 107 98 100 1 1

1 1E-053 gi|170036732 211

proteasome subunit beta type 6 [Culex quinquefasciatus] 107 227 97 47 123 1

13 2E-049 gi|170032258

prefoldin [Culex quinquefasciatus] 197 107 137 95 78 32 1

1 9E-055 gi|170049421 215

60S ribosomal protein L31 [Culex quinquefasciatus] 106 124 99 85 19 1

9 6E-056 gi|170064276 219

glutamate carboxypeptidase [Culex quinquefasciatus] 106 480 98 22 375 1

65 3E-054 protein [Culex 213

conserved hypothetical gi|170039080 quinquefasciatus] 106 406 95 26 301 1

1 4E-055 gi|170059700 216

60S ribosomal protein L15 [Culex quinquefasciatus] 106 149 94 71 44 1

53 2E-048 protein [Culex 194

conserved hypothetical gi|170056627 quinquefasciatus] 106 243 88 44 138 1

8 4E-057 gi|157113951

dynein light chain, putative [Aedes aegypti]223 105 111 100 95 7 1

1 9E-055 gi|170044360 215

60S ribosomal protein L35a [Culex quinquefasciatus] 104 144 99 72 41 1

21 1E-055 gi|170028542

lethal 35Di [Culex quinquefasciatus] 218 104 162 97 64 59 1

23 1E-030 protein

conserved hypothetical gi|170051165 137 104 172 60 60 68 1

20 5E-051 gi|170043977

ribosomal protein S16 [Culex quinquefasciatus]202 103 148 99 70 46 1

1 5E-048 gi|157116671

60S ribosomal protein L9 [Aedes aegypti] 192 103 190 94 54 88 1

7 4E-039 gi|170067711 163 103

ezrin-radixin-moesin-binding phosphoprotein 50 [Culex quinquefasciatus]

286 88 36 187 1

1 NADH-ubiquinone oxidoreductase AGGG subunit [Culex

mitochondrial 3E-052 gi|170046848 206 102 102 93 100 1 1

29 1E-045 protein [Culex 184

conserved hypothetical gi|170044015 quinquefasciatus] 102 100 90 102 1 1

55 3E-051 protein [Culex 203

conserved hypothetical gi|170028023 quinquefasciatus] 101 458 99 22 358 1

48 5E-052 gi|170044328 206

hypothetical protein CpipJ_CPIJ008169 [Culex quinquefasciatus] 101

101 98 100 1 1

Orientatio Best Best

Number n of match to match to Function Function

of assemble KOG General GO descripto Function second

segments d output Species database E value class database E value rs parent parent

32 FOR Muscarinic acetylcholine receptor

3E-004 Signal

Culex quinquefasciatus] quinquefasciatus transduction mechanisms

1 FOR 26S proteasome regulatory complex, ATPase RPT40 protein turnover,catalytic activity

Rpt4 modification, ATPase - proteasome regulatory particle, base subcomplex

chaperones hydrolase activity

Culex quinquefasciatus 1E-150 Posttranslational - Drosophila melanogaster activity||nucleoside\-triphosphatase activity||pyroph

1 FOR Culex quinquefasciatus 1E-104 Carbohydrate transport Drosophila melanogaster - 1,4-alpha-glucan branching enzyme activity

1,4-alpha-glucan branching enzyme/starch branching enzyme II

CG33138 - and metabolism

0 activity||catalytic

transferase

transferase catalytic activity activityactivity

1 FOR Ca2+ transporting ATPase Calcium ATPase0at 60Acalcium\-transportingactivity - calcium-transporting ATPase a

Culex quinquefasciatus 1E-146 Inorganic ion transport and metabolism catalytic ATPase

hydrolase activity

- Drosophila melanogaster activity||ATPase activity\, cou

1 FOR ATP-citrate quinquefasciatus production and conversion ATP citrate catalytic activity

1E-136 Energy

Culex quinquefasciatus]lyase synthase activity||transferase activity\, transferrin

transferase activity

ATP citrate lyase0- Drosophila melanogaster - acetyl-CoA biosynthetic process - citr

1 FOR Predicted ATP-dependent proteasecereblon - Rattus norvegicus - protein binding

PIL, prediction onlydomain

LON

Culex quinquefasciatus 2E-021 General function contains 8E-29 molecular_function molecular_function

1 FOR Aedes aegypti

F0F1-type ATP synthase, beta subunit synthase-beta - Drosophila melanogaster - hydrogen-exporting ATPase activit

1E-167 Energy production and conversion hydrogen\-exporting activity activity\, phosphorylative mech

ATP 0 catalytic ATPase

hydrolase activity

1 FOR NADP+-dependent malic enzyme Malic enzyme - Drosophila melanogaster - malate dehydrogenase (oxaloacetate-de

0 catalytic activity

(oxaloacetate\-decarboxylating) (NA

Culex quinquefasciatus 1E-151 Energy production and conversion malate dehydrogenase oxidoreductase activity

1 FOR UDP-glucuronosyl and Carbohydrate transport Drosophila glucuronosyltransferasetransferase activity

CG10178 - and metabolism, Energy - glucuronosyltransferase activity

catalytic activity conversion

and

Culex quinquefasciatus 2E-021 UDP-glucosyl transferase 4E-77 melanogaster production activity||transferase activity\, transfe

1 FOR Actin and 1E-151 Cytoskeleton

Nasonia vitripennis related proteins Actin 5C - Drosophila melanogasterstructural of structural constituent of cytoskeleton

0 structural constituent molecule activitycytoskeleton - actinac

- structural cytoskeleton||structural molecule fil

constituent of

1 FOR Culex quinquefasciatus 1E-106 Lipid transport and Drosophila melanogaster - polyphosphoinositide phosphatase activity - dors

Putative phosphoinositide phosphatase - metabolism

Sac1 0 catalytic activity

hydrolase activity

phosphatase activity||phosphoric ester hydrolase activity||hy

1 FOR Acetyl-CoA 1E-125 Lipid

Culex quinquefasciatus acetyltransferasetransport and interacting protein 2 - Drosophila melanogaster activity||C\-acyltransferase a

yippee metabolism 0 C\-acyltransferase

transferase activity

acetyl\-CoA catalytic activity - acetyl-CoA C-acyltransfera

5 FOR Predicted RNA binding General function prediction only

5E-006

Culex pipiens quinquefasciatus protein, contains SWAP, RPR and G-patch domains

1 FOR Culex quinquefasciatus 1E-144 GRP78/BiP/KAR2, HSP70 superfamily turnover,catalytic activity

Molecular chaperones Posttranslational shock proteinprotein 3 - Drosophila melanogaster -activity activity||pyroph

Heat modification, cognate

0 ATPase activity||nucleoside\-triphosphatase to heat - ATPa

chaperones hydrolase response

1 FOR Elongation factor 2

1E-166 Translation,Elongation structure and biogenesistranslationfactor activity||translation factor activit

Culex quinquefasciatus] quinquefasciatus translation elongation regulator activity

- translation - translation nucleic ac

ribosomal factor02b - Drosophila melanogastertranslation factor activity\, elongation

1 FOR WD40 repeat-containing protein Retinoid- 4E-48 retinol binding||retinoid binding||isoprenoid binding||binding

binding isoprenoid binding

Culex quinquefasciatus 0.45 Function unknown and fatty acid-binding glycoprotein - Drosophila melanogaster - retinol bin

1 FOR Mitochondrial 1E-149 Translation,Elongation structure and biogenesistranslationfactor activity||translation factorelonga

translation elongation ribosomal factor0Tu mitochondrial elongation regulator activity translational activit

Culex quinquefasciatus] quinquefasciatus factor Tu melanogaster -

translation - Drosophilatranslation factor activity\, nucleic ac

1 FOR Histidyl-tRNA synthetase ribosomal structure and - Drosophila melanogaster - histidyl-tRNA

0 ATP binding||adenyl nucleotide binding||purine ribonucle

Culex quinquefasciatus 1E-125 Translation,Histidyl-tRNA synthetasebiogenesisbinding ribonucleotidebinding aminoacylation

1 FOR Aminomethyl transferase transport Drosophila melanogastercatalytic activity

Culex quinquefasciatus 6E-098 Amino acid CG6415 -and metabolism - aminomethyltransferase activity - glycine clea

transferase activity

3E-94 aminomethyltransferase activity||methyltransferase activity||

1 FOR Vesicle coat 1E-069 Intracellular trafficking, secretion, and subunit binding

subunit 1E-78 protein binding||binding protein - protein

transport

Culex quinquefasciatus complex COPI, epsilonCOPE, COPE1: Coatomervesicularepsilon - Bos taurusbinding binding - retrograd

1 FOR Ubiquinol cytochrome reductase, subunit QCR2 9E-39 reductase core protein 2 - Rattus norvegicus - protein bindin

ubiquinol cytochrome catalytic activity

hydrolase activity

Culex quinquefasciatus 3E-046 cEnergy production and conversionc metalloendopeptidase activity||metallopeptidase activity||pep

1 FOR Puromycin-sensitive Amino acid ENPEP: Glutamyl aminopeptidase -catalytic activity

transport and aminopeptidases

4E-25 aminopeptidase activity||exopeptidase activity||peptidase ac

Homo modification, protein turnover, chaperon

hydrolase activity

Culex quinquefasciatus 3E-031aminopeptidase and related metabolism, Posttranslationalsapiens - cell-cell signaling - cell prolifera

1 FOR Animal-type 2E-063 Lipid transport and metabolism melanogasterbinding

related - Drosophila identical protein binding||protein binding||binding

Culex quinquefasciatus fatty acid synthase andCG3523 proteins 2E-63 synthase activity

- fatty-acid protein binding - lipid particle

1 FOR 3-hydroxyacyl-CoA dehydrogenasehydroxyacyl-Coenzyme3\-hydroxybutyryl\-CoA oxidoreductase activity

Culex quinquefasciatus 1E-100 Lipid transport and metabolism catalytic activity

dehydrogenase activity||oxidoreduct

3E-93 A dehydrogenase - Mus musculus - 3-hydroxyacyl-CoA deh

1 FOR Transcription 0.014 Transcription DnaJ homolog, subfamily C, member 2 - Mus binding - protein

binding protein musculus

Culex quinquefasciatus factor, Myb superfamily (Hsp40) 2E-16 unfolded protein binding||protein binding||binding binding -

1 FOR 26S proteasome regulatory complex, ATPase RPT60 melanogaster chaperones

Pros45 - Drosophila endopeptidase activity||peptidase activity

endopeptidasehydrolase activity||hydrolase activity

Culex quinquefasciatus 1E-135 Posttranslational modification, protein turnover,-catalytic activity activity - proteasome regulatory

1 FOR Phosphoribosylamidoimidazole-succinocarboxamide0synthase

ade5 - Drosophila melanogaster - phosphoribosylaminoimidazole carboxylase activ

Culex quinquefasciatus 4E-040 Nucleotide transport and metabolism catalytic activity activity

lyase

phosphoribosylaminoimidazole carboxylase activity||carboxy

1 FOR Thyroid hormone receptor-associated gawky - Drosophila subunit TRAP230

4E-39

Culex quinquefasciatus 0.010 Transcription protein complex, melanogaster - nuclear-transcribed mRNA catabolic process, no

1 FOR Trypsin

Culex quinquefasciatus] quinquefasciatus acid easter - Drosophila melanogaster - catalytic activity activity||serine\-type peptidase a

4E-050 Amino 2E-51 serine\-type Toll signaling pathwayactivity

transport and metabolism endopeptidasehydrolase - dorsal/ventral axis spec

1 FOR Membrane 1E-004 LIG-1 Peroxidasin - Drosophila melanogaster - proteinaceousbinding

0.0004 binding protein extracellular matrix - peroxi

Culex quinquefasciatusglycoproteinSignal transduction mechanisms actin binding||cytoskeletal protein binding||protein binding||b

1 FOR Branched chain alpha-keto acid dehydrogenase complex, alpha subunit- 3-methyl-2-oxobutanoate activity

CG8199 - conversion 3\-methyl\-2\-oxobutanoate

0 oxidoreductase dehydrogenase (2-m

Culex quinquefasciatus 1E-108 Energy production andDrosophila melanogastercatalytic activity dehydrogenase (2\-methylpropa

46 FOR Myosin class I1E-004 chain

heavy Cytoskeleton

Culex quinquefasciatus] quinquefasciatus

1 FOR Placental protein 11 CG2145 - Drosophila molecular_function

3E-90 - serine-type peptidase activity

Culex quinquefasciatus 9E-069 General function prediction only melanogastermolecular_function

1 FOR Placental protein 11 CG2145 - Drosophila molecular_function

3E-90 - serine-type peptidase activity

Culex quinquefasciatus 9E-069 General function prediction only melanogastermolecular_function

1 FOR 40S ribosomal protein Translation,ribosomal protein SA - Mus musculus - laminin binding activity

ribosomal structure structural constituent molecule

1 ribosome||structural of ribosome

Culex quinquefasciatus 1E-071 SA (P40)/Laminin receptor 3E-79 and biogenesisstructural of structural constituentmolecule activit

1 FOR Aedes aegypti

Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases acid phosphorylation - protein

4E-079 Signal transduction mechanisms melanogaster - protein amino

Cad96Ca - Drosophila protein tyrosine kinase activity||protein kinase activity||phosp

0 catalytic activity

transferase activity

1 FOR Translocon-associated Intracellular lethal (1) subunit and vesicular binding

trafficking, secretion, signal sequence binding||peptide binding||binding

8E-92 transport peptide binding

Culex quinquefasciatus 8E-073 complex TRAP, alphaG0320 - Drosophila melanogaster - signal sequence binding - signal recog

1 FOR RNA binding 0.067 General function microtubule-associated protein - Drosophila melanogaster - cis-Golgi network

6E-36

Culex quinquefasciatus protein RBM12/SWANGolgi prediction only molecular_function molecular_function

1 FOR Putative Mg2+ and Co2+ transporter CorD

polymerase (DNA-directed),

8E-92 molecular_function

molecular_function

Culex quinquefasciatus 3E-085 Inorganic ion transport and metabolism delta interacting protein 2 - Mus musculus - mitochond

2 FOR Cytoskeleton-associated protein and General function prediction - Drosophila protein binding

Cytoplasmic linker

1E-73 microtubule binding||tubulin binding||cytoskeletal protein m

Culex quinquefasciatus 1E-023 Cytoskeleton,related proteins protein 190only binding melanogaster - microtubule binding -bin

1 FOR Acetyl-CoA 1E-120 Lipid Thiolase - Drosophila acetyl\-CoA C\-acyltransferase

0 - acetyl-CoA C-acyltransferase activity - fatty a

transferase activity

Culex quinquefasciatus acetyltransferasetransport and metabolism melanogastercatalytic activity activity||C\-acyltransferase ac

1 FOR Beta, beta-carotene Secondary metabolitesProtein CDV3 homolog -and catabolism

GE14456: biosynthesis, transport molecular_function - cellular_component - biolo

1E-14 molecular_function

Culex quinquefasciatus 0.44 15,15'-dioxygenase and related enzymes Drosophila yakuba

1 FOR Mitochondrial ribosomal protein L17 ribosomal structure and protein L46molecular_function

2E-63 biogenesis - Drosophila melanogaster - structural constitue

Culex quinquefasciatus 5E-041 Translation,mitochondrial ribosomalmolecular_function

1 FOR NAD-dependent malate dehydrogenase CG7998 - conversion L\-malate dehydrogenase activity||oxidoreductase activity\, a

2E-95 - L-malate dehydrogenase activity - mitochondr

Culex quinquefasciatus 6E-098 Energy production andDrosophila melanogastercatalytic activity oxidoreductase

1 FOR Uncharacterized conserved protein Arabidopsis thaliana - biological_process - cellular_component - molecular_function

Culex quinquefasciatus 2E-028 Function unknown molecular_function

3E-24 molecular_function

1 FOR Galactokinase GALK1, GALK: metabolism

7E-67 galactokinase sapiens transferase activity

catalytic activity

- galactokinase activity - ATP bindin

Culex quinquefasciatus 3E-023 Carbohydrate transport andGalactokinase - Homoactivity||phosphotransferase activity\, alcohol

1 FOR 60S ribosomal protein Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 2E-060 L5 0 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein L5 - Drosophila melanogaster - cytosolic large ribosomal subunit

1 FOR Vacuolar H+-ATPase Energy production H[+]-ATPase hydrogen\-exporting activity activity\, phosphorylative mech

Vacuolar 4E-92 catalytic ATPase

hydrolase activity

Culex quinquefasciatus 9E-068 V1 sector, subunit E and conversion 26kD E subunit - Drosophila melanogaster - hydrogen-expor

1 FOR Ribosome biogenesis RNA RPF1, contains Drosophila

CG6712 IMP4 domain

1E-94

Culex quinquefasciatus 9E-068 proteinprocessing and -modification melanogaster - RNA binding - nucleolus

1 FOR Elongation 6E-073 Transcription 7E-78 - Drosophila melanogaster - translation release factor activ

translation regulator activity activity\, nucleic ac

translation factor

Culex quinquefasciatusfactor 1 beta/delta chainElongation factor 1 betatranslation release factor activity||translation termination fact

1 FOR Ferritin 2E-011 Inorganic Ferritin 2 light 6E-33homologue - Drosophila ion binding

chain ferrous binding||iron ion binding||transition metal ion bin

Culex quinquefasciatus] quinquefasciatus ion transport and metabolism iron binding melanogaster - cellular iron ion homeo

1 FOR 40S 3E-098 Translation,string of pearls - Drosophila melanogaster - translation activity

ribosomal structure structural constituent molecule - constituentmolecule of rib

ribosome||structural of ribosome

Aedes aegypti ribosomal protein S2/30S ribosomal protein S5 0 and biogenesisstructural of structuralstructural constituent activit

1 FOR Actin and 1E-112 Cytoskeleton

Nasonia vitripennis related proteins Actin 5C - Drosophila melanogasterstructural of structural constituent of cytoskeleton

0 structural constituent molecule activitycytoskeleton - actinac

- structural cytoskeleton||structural molecule fil

constituent of

1 FOR 40S ribosomal protein Translation,ribosomal protein S3and biogenesisstructural of structural constituentmolecule- activit

Culex quinquefasciatus 8E-096 S3 0 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal structure - Rattus norvegicus - structural constituent of ribosome prote

1 FOR 60s ribosomal protein Translation,Qm - Drosophila 0 and biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 1E-080 L10 melanogaster - constituent structural constituent ofof ribosome cyt

ribosome||structural ribosome -

ribosomal structure structuraltranslation - molecule activity

1 FOR F0F1-type ATP synthase, gamma subunitATP synthase-gamma hydrogen\-exporting activity activity\, phosphorylative ATPa

1E-94 catalytic ATPase

hydrolase hydrogen-exporting mech

Culex quinquefasciatus 2E-075 Energy production and conversion chain - Drosophila melanogaster - activity

1 FOR Cellular repressor of Transcription 5E-39 protein binding||binding protein binding

binding

Culex quinquefasciatus 7E-045transcription Cellular Repressor of E1A-stimulated Genes - Drosophila melanogaster - negative r

1 FOR Predicted G-protein coupled receptor GPR89A, GPR89, GPR89B, transducer activity||molecular transducer activity

1E-82 molecular transducer activity activity

signal transducer

Culex quinquefasciatus 4E-085 Signal transduction mechanisms signalCGI-13, SH120, HSPC201, UNQ192/PRO218: Protein

3 FOR Prosaposin PSAP, metabolism, Proactivator transport regulator activity

SAP1: enzyme activator activity||enzyme regulator Saposin-A - Hom

enzyme and metabolism

enzyme [Contains: activity

Culex quinquefasciatus 1E-011 Lipid transport and GLBA, 1E-19 Carbohydratepolypeptide precursoractivator activity

1 FOR Hydroxypyruvate isomerase hydroxypyruvate isomerase,

4E-45 hydroxypyruvate isomerase activity||intramolecular oxidored

catalytic activity

isomerase activity

Culex quinquefasciatus 5E-062 Carbohydrate transport and metabolism putative - Pseudomonas syringae pv. phaseolicola - hy

3 FOR G-protein beta subunit G protein beta-subunit GTPase activity||nucleoside\-triphosphatase activity||pyroph

0 catalytic activity

hydrolase activity

Culex quinquefasciatus 4E-095 General function prediction only 13F - Drosophila melanogaster - G-protein coupled receptor

1 FOR Nuclear transport receptor LGL2 (importin beta -superfamily)

importin 13 Rattus norvegicusbinding||binding protein binding

6E-19 protein - protein binding - NLS-dependent

binding

Culex quinquefasciatus 2E-029 Nuclear structure, Intracellular trafficking, secretion, and vesicular transport protein nuclear im

1 FOR Mitochondrial phosphate carrier protein

Mitochondrial phosphate carrier protein - Drosophila melanogastertransporter activit

1E-89 transporter activity

substrate\-specific - phosphate an

Culex quinquefasciatus 2E-099 Energy production and conversion phosphate transmembrane transporter activity||inorganictran

1 FOR 60s ribosomal protein Translation,ribosomal protein L23a protein binding||binding protein binding cytosol - translational

Culex quinquefasciatus 1E-030 L23 7E-46 - Rattus norvegicus

ribosomal structure and biogenesisbinding - protein binding -

1 FOR 40S ribosomal protein Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Aedes aegypti] aegypti 4E-020 S6 2E-37 Drosophila melanogaster - translation

ribosome||structural of ribosome

ribosomal protein S6 - structural constituent molecule activity- structural constituen

1 FOR Translation 1E-064 Translation,eIF3-S9 - Drosophila melanogaster - translational initiation -binding

ribosomal structure mRNA binding||RNA nucleic acid acid binding||binding

Culex quinquefasciatus initiation factor 3, subunit b (eIF-3b) 4E-81 and biogenesisbinding binding||nucleic mRNA binding - transla

1 FOR 60s ribosomal protein Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 2E-084 L2/L8 4E-98 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein L8 - Drosophila melanogaster - translation - structural constituen

1 FOR Cell cycle-associated Cell cycle control, cell division, chromosome partitioning 2B (yeast) - Rattus norvegicus - protei

Culex quinquefasciatus 3E-099 protein 6E-80

MOB1, Mps One Binder kinase activator-like

1 FOR Monocarboxylate transporter CG13907 - and metabolism

3E-59

Culex quinquefasciatus 8E-025 Carbohydrate transport Drosophila melanogaster - secondary active monocarboxylate transmem

1 FOR Na+/K+ ATPase, alpha Inorganic ion transport and metabolism

Aedes aegypti 1E-158 subunit Na pump alpha subunit sodium\:potassium\-exchanging ATPase activity||ATPase ac

0 - Drosophila melanogaster - sodium:potassium-exchanging

catalytic activity

hydrolase activity

1 FOR 40S ribosomal protein Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 3E-071 S8 7E-78 Drosophila melanogaster - translation

ribosome||structural of ribosome

ribosomal protein S8 - structural constituent molecule activity- structural constituen

1 FOR Uncharacterized conserved protein coiled-coil 5E-35 molecular_functionrerio - biological_process

Danio

Culex quinquefasciatus 2E-023 Function unknown domain containing 124 - molecular_function

1 FOR WD40 repeat protein cirrhosis, autosomal molecular_function

2E-07 molecular_function

Culex quinquefasciatus 2E-009 General function prediction only recessive 1A (human) - Mus musculus - biological_process - c

1 FOR Aedes aegypti

GTP-binding protein CRFG/NOG1 (ODNprediction only melanogastercatalytic activity- nucleus

1E-066 General function superfamily)

CG8801 - Drosophila GTPase activity||nucleoside\-triphosphatase activity||pyroph

9E-94 - GTP bindinghydrolase activity

4 FOR Translation 6E-007 Translation, ribosomal structure and biogenesis

Culex quinquefasciatus initiation factor 5B (eIF-5B)

1 FOR Ubiquinol cytochrome reductase, subunit QCR2 4E-17 reductase core protein 2 - Mus musculus - mitochondrion - m

ubiquinol cytochrome catalytic activity

hydrolase activity

Culex quinquefasciatus 2E-021 cEnergy production and conversionc metalloendopeptidase activity||metallopeptidase activity||pep

1 FOR Uncharacterized conserved protein gryzun 1E-33

Culex quinquefasciatus 1E-009 Function unknown - Drosophila melanogaster - cellular_component - learning and/or memory -

1 FOR Glycosyltransferase CG11306 - Drosophila melanogaster - alpha-1,2-mannosyltransferase activity

8E-67 alpha\-1\,2\-mannosyltransferase activity||mannosyltransfera

Culex quinquefasciatus 4E-056 Cell wall/membrane/envelope biogenesis transferase activity

catalytic activity

1 FOR Culex quinquefasciatus 2E-64 calcium ion binding

binding||metal ion binding||ion binding||binding

ion binding

protein disulfide isomerase associated 6 - Rattus norvegicus - calcium ion binding -

1 FOR Uncharacterized conserved protein integral 1E-08 molecular_function

molecular_function

Culex quinquefasciatus 8E-030 Function unknown membrane protein 2A - Mus musculus - integral to membrane

1 FOR 60S ribosomal protein Translation,Ribosomal structure and -biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 2E-068 L18A 2E-83 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein L18A Drosophila melanogaster - translation - structural constitu

1 FOR Hexokinase Hexokinase A 9E-76 hexokinase catalytic activity

- metabolism activity||phosphotransferase

transferase activity

Culex quinquefasciatus 1E-052 Carbohydrate transport andDrosophila melanogaster - hexokinase activity activity\, alcohol gro

1 FOR Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3)

Culex quinquefasciatus 0.79 Cell cycle control, cell division, chromosome partitioning

1 FOR Mitochondrial ribosomal protein S28ribosomal structure and protein S35 - Drosophila melanogaster - translation - struct

5E-58 biogenesisstructural molecule activity

ribosome||structural of ribosome

Culex quinquefasciatus 4E-039 Translation,mitochondrial ribosomalstructural constituent of structural constituentmolecule activit

1 FOR 60S ribosomal protein Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 5E-054 L7 3E-77 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein L7 - Drosophila melanogaster - translation - structural constituen

1 FOR Culex quinquefasciatus 2E-10 molecular_function

- molecular_function

CG2182 - Drosophila melanogastermolecular_function - cellular_component - bio

1 FOR Culex quinquefasciatus 1E-12 melanogaster - axon

molecular_function

Fasciclin 3 - Drosophilamolecular_function guidance - synaptic target recognition

1 FOR tRNA-binding protein ribosomal structure and biogenesis - aminoacyl-tRNA synthetase auxiliary protein a

3E-75 tRNA binding||RNA nucleic acid acid binding||binding

Culex quinquefasciatus 1E-054 Translation,CG8235 - Drosophila melanogasterbinding binding||nucleic binding

1 FOR Uncharacterized conserved protein zgc:123177 - Danio rerio - biological_process - molecular_function - cellular_compo

Culex quinquefasciatus 2E-050 Function unknown molecular_function

4E-54 molecular_function

1 FOR 40S ribosomal protein Translation,ribosomal protein S3and biogenesisstructural of structural constituentmolecule- activit

Culex quinquefasciatus 3E-068 S3 2E-71 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal structure - Rattus norvegicus - structural constituent of ribosome prote

1 FOR 40S ribosomal protein Translation,ribosomal protein S7and biogenesisstructural of structural constituentmolecule- activit

Culex quinquefasciatus 5E-060 S7 5E-67 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal structure - Rattus norvegicus - structural constituent of ribosome prote

1 FOR Mitochondrial associated endoribonuclease MAR1 only catalytic superfamily)

isochorismatase domain containingcatalytic activity

7E-39 1-

Culex quinquefasciatus 2E-053 General function prediction (isochorismataseactivityDanio rerio - cellular_component

1 FOR Mitochondrial F1F0-ATP synthase, ATP synthase,1E-62 hydrogen\-exporting activity hydrogen-exporting ATPase a

subunit b/ATP4subunit catalytic ATPase

hydrolase activity

Culex quinquefasciatus 8E-038 Energy production and conversion b - Drosophila melanogaster -activity\, phosphorylative mech

1 FOR Golgi-associated protein/Nedd4 WW domain-binding proteinprotein 1 - molecular_function

Nedd4 family interacting

1E-20 Danio

Culex quinquefasciatus 1E-040 General function prediction only molecular_functionrerio - cellular_component - biological_pr

1 FOR Vesicle coat quinquefasciatus

3E-029 Intracellular Clathrin light chain - Drosophila melanogaster -activity vesicle coat - coatedactivity

trafficking, secretion, and vesicular transporter neurotransmitter transporter pit - ne

Culex quinquefasciatus] protein clathrin, light chain transport clathrin

1E-36 neurotransmitter transporter activity||transporter activity

1 FOR Leucine-rich 0.006 Function unknown

Culex quinquefasciatus repeat protein 0.001

zgc:103699 - Danio rerio - biological_process

1 FOR Cyclophilin type peptidyl-prolyl cis-trans isomeraseDrosophila melanogaster - peptidyl-prolyl cis-trans isomerase activity

Aedes aegypti Cyclophilin 1 - 3E-78 peptidyl\-prolyl cis\-trans isomerase activity||cis\-trans isome

chaperones

4E-069 Posttranslational modification, protein turnover,catalytic activity isomerase activity

1 FOR Cytoplasmic 0.006 General function prediction only

Culex quinquefasciatus Zn-finger protein BRAP2 (BRCA1 associated protein)

1 FOR 40S ribosomal protein Translation,Ribosomal structure and -biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 4E-055 S19 1E-62 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein S19a Drosophila melanogaster - translation - structural constitu

1 FOR Translation 9E-061 Translation,Ef1gamma structure andmelanogaster - translationalactivity||translation factorelonga

ribosomal - Drosophilatranslation elongation factor elongation -activity\, nucleic ac

Culex quinquefasciatus elongation factor EF-1 gamma 4E-79 translation factor

biogenesistranslation regulator activity translation activit

1 FOR Vacuolar H+-ATPase Energy production VhaPPA1-1 - Drosophila melanogaster - hydrogen-exporting phosphorylative mech

8E-63 catalytic ATPase

hydrolase activity

Culex quinquefasciatus 8E-045 V0 sector, subunit c''and conversion hydrogen\-exporting activity activity\,ATPase activity, phosp

1 FOR UDP-glucose 3E-067 Carbohydrate transport and metabolism

Aedes aegypti 2E-81 UTP\:glucose\-1\-phosphate uridylyltransferase activity||UTP

catalytic activity

transferase activity

pyrophosphorylase UGP - Drosophila melanogaster - UTP:glucose-1-phosphate uridylyltransferase act

1 FOR Culex quinquefasciatus

1 FOR 40S ribosomal protein Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 9E-048 S3A 3E-61 - Drosophila melanogaster - translation

ribosome||structural of ribosome

ribosomal protein S3A structural constituent molecule activity - structural constitue

1 FOR Kynurenine 2E-011 Amino acid zgc:112472 - Danio rerio - biological_process - hydrolase activity acting on carbo

Culex quinquefasciatus formamidase 9E-14 arylformamidase activity||hydrolase activity\,

transport and metabolism cellular_component

catalytic activity

2 FOR 60S

Aedes aegypti ribosomal protein L36

3E-018 Translation,Ribosomal structure and Drosophilastructural of structural constituentmolecule activit

ribosomal protein L36 -structural constituent molecule activity - structural constitue

2E-39 biogenesis melanogaster - translation

ribosome||structural of ribosome

1 FOR Threonine/serine dehydratases transport Drosophila melanogastercatalytic activity activity||ammonia\-lyase activit

Culex quinquefasciatus 2E-038 Amino acid CG8129 -and metabolism ammonia\-lyase activity

lyase

5E-49 L\-threonine - L-threonine ammonia-lyase activity

1 FOR Mitochondrial 0.087 Intracellular NDUFA11: secretion, and vesicular[ubiquinone] 1 alpha subcomplex subunit 11 - Bo

trafficking, NADH dehydrogenase transport

0.0001

Culex quinquefasciatus import inner membrane translocase, subunit TIM23

1 FOR Uncharacterized protein PSP1 (suppressor of DNA polymerase alpha mutations in yeast)

Culex quinquefasciatus 0.11 General function prediction only

1 FOR Anopheles gambiae str. 6-sulfotransferase and carbohydrate (chondroitin 4) sulfotransferase 13 - Rattus norvegicus - N-acetylgalac

Chondroitin PEST] gambiaewall/membrane/envelope biogenesis, Extracellular structures

0.002 Cell str. PEST 0.000005 sulfotransferase activity||transferase activity\, transferring su

related sulfotransferases transferase activity

catalytic activity

1 FOR Ras-related 2E-056 Rab-protein 7 5E-69 GTPase activity||nucleoside\-triphosphatase activity||pyroph

- only catalytic activity

hydrolase activity

Culex quinquefasciatus GTPase General function prediction Drosophila melanogaster - GTPase activity - endosome to lysosome

1 FOR Anopheles gambiae str. PEST] gambiae str. PEST and conversion citrate (Si)\-synthaseactivity

Citrate synthase

5E-058 Energy production

AAEL002956: 1E-79 citrate synthase 1, mitochondrial precursor - Aedes aegypti

Probable transferase activity

catalytic activity||transferase activity\, transferrin

1 FOR Predicted membrane Function unknown

Culex quinquefasciatus 2E-025 protein 8E-37 protein binding||binding protein binding

binding

RCJMB04_2c17: Putative uncharacterized protein - Gallus gallus - protein binding -

1 FOR 60s ribosomal protein Translation,Ribosomal structure and Drosophilastructural of structural constituentmolecule activit

Culex quinquefasciatus 9E-032 L19 9E-55 biogenesis melanogaster - translation

ribosome||structural of ribosome

ribosomal protein L19 -structural constituent molecule activity - structural constitue

1 FOR Long-chain 1E-025 Lipid transport and metabolism

bubblegum - 2E-53 melanogaster - long-chain-fatty-acid-CoA ligase activity - lo

catalytic activity activity

ligase

Culex quinquefasciatus acyl-CoA synthetases (AMP-forming)Drosophilalong\-chain\-fatty\-acid\-CoA ligase activity||fatty\-acid ligase

1 FOR 60S ribosomal protein Translation,Ribosomal protein L3 - Drosophila melanogaster - translation - structural constituen

ribosomal 2E-63 structural constituent molecule activity

ribosome||structural of ribosome

Culex quinquefasciatus 5E-045 L3 and related proteins structure and biogenesisstructural of structural constituentmolecule activit

1 FOR Calsyntenin

Culex quinquefasciatus 0.56 Extracellular structures

1 FOR GTPase Rab11/YPT3, Intracellular Rab-proteinsecretion, and vesicular catalytic GTPase

trafficking, 11 1E-66 GTPase activity||nucleoside\-triphosphatase activity||pyroph

transport hydrolase activity

Culex quinquefasciatus 5E-049 small G protein superfamily - Drosophila melanogaster - activity activity - oogenesis - GTP bind

1 FOR Membrane-associated Signal tyrosine phosphatase PTP-BAS and related proteins, contain FERM domain

Culex quinquefasciatus 0.013 protein transduction mechanisms

1 FOR Ribosomal protein S4 Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Aedes aegypti 2E-047 9E-65 Drosophila melanogaster - translation

ribosome||structural of ribosome

ribosomal protein S9 - structural constituent molecule activity- structural constituen

1 FOR Beta, beta-carotene Secondary metabolites biosynthesis, transport and catabolism

CG3760 Drosophila melanogastermolecular_function - cellular_component - bio

Culex quinquefasciatus 0.14 15,15'-dioxygenase and-related enzymes8E-10 molecular_function- molecular_function

1 FOR Alkyl hydroperoxide reductase,

1E-063 Posttranslational modification, protein- turnover,activity

specific antioxidant and Drosophila melanogaster - antioxidant activity - thioredox

3E-63 antioxidant antioxidant activity

Culex quinquefasciatus] quinquefasciatus thiolthioredoxin peroxidase 2 related enzymes chaperones

1 FOR Carnitine O-acyltransferase transport and metabolism 6E-63 G\-protein coupled receptor kinase activity||protein serine/th

catalytic activity

transferase activity

Culex quinquefasciatus 0.16 LipidCRAT SNF1A/AMP-activated protein kinase - Drosophila melanogaster - protein amino ac

2 FOR Annexin trafficking, Drosophila calcium\-dependent lipid binding phospholipid binding - c

7E-45 melanogaster - calcium-dependent

transport

Culex quinquefasciatus 1E-040 Intracellular Annexin X -secretion, and vesicular binding phospholipid binding||phospholipid bind

1 FOR Ubiquitin-like/40S ribosomal S30 protein fusionprotein S30 - biogenesis,melanogaster - structural constituent of ribosom

ribosomal 9E-36 structural constituent moleculemodification, molecule activit

Posttranslational activity

ribosome||structural of ribosome

Culex quinquefasciatus 3E-019 Translation,Ribosomal structure and Drosophilastructural of structural constituentprotein turnover

1 FOR Molecular chaperones Posttranslational shock proteinprotein turnover,catalytic activity

Heat modification, cognate 3 - activity||nucleoside\-triphosphatase to heat - ATPa

superfamily chaperones hydrolase response

Culex quinquefasciatus 2E-047 GRP78/BiP/KAR2, HSP70 2E-56 ATPaseDrosophila melanogaster -activity activity||pyroph

1 FOR RNA polymerase subunit K RNA 4E-45 DNA\-directed RNA polymerase activity||RNA polymerase a

catalytic activity

transferase activity

Culex quinquefasciatus 8E-041 Transcription polymerase II 18kD subunit - Drosophila melanogaster - DNA-directed RNA po

1 FOR Ubiquitin/40S ribosomal protein S27a fusion structure and biogenesisbinding

ribosomal 3E-58 protein binding||binding protein binding

Culex quinquefasciatus 2E-048 Translation,Ubiquitin-63E - Drosophila melanogaster - protein modification process - response t

1 FOR Gelatinase 1E-012 Posttranslational modification, protein1turnover,catalytic activity - metalloendopeptidase activ

Matrix metalloproteinase - Drosophila melanogaster activity

chaperones, Extracellular structures

hydrolase

Culex quinquefasciatusA and related matrix metalloproteases7E-17 metalloendopeptidase activity||metallopeptidase activity||pep

1 FOR Culex quinquefasciatus

1 FOR Aryl-hydrocarbon receptor-interacting protein Drosophila melanogaster chaperones activity||transcription cofactor activit

CG1847 - 3E-38 transcription -coactivatorprotein binding binding

Culex quinquefasciatus 8E-038 Posttranslational modification, protein turnover,binding aryl hydrocarbon receptor

1 FOR Cysteine proteinase Posttranslational modification, protein cellular_component hydrolase activity activity||hydrolas

2E-44 cysteine\-type peptidase activity||peptidase

chaperones

Culex quinquefasciatus 8E-025Cathepsin L zgc:110239 - Danio rerio - turnover,catalytic activity

1 FOR Culex quinquefasciatus

1 FOR Protein DRE2, required for cell viability

CIAPIN1, 5E-30 molecular_function

molecular_function

Culex quinquefasciatus 1E-029 Function unknown CUA001, PRO0915: Anamorsin - Homo sapiens - anti-apoptosis - cytopla

1 FOR Protein kinase 0.81 Signal transduction mechanisms, Chromatin DNA repair

Culex quinquefasciatus ATM/Tel1, involved in telomere length regulation and structure and dynamics, Replication, recombinatio

1 FOR Focal adhesion protein Signal contains PTB domain

Culex quinquefasciatus 0.51 Tensin,transduction mechanisms, Cytoskeleton

1 FOR Mitochondrial glycerol-3-phosphate CG5508 - Drosophila glycerol\-3\-phosphate O\-acyltransferase activity||O\-acyltra

acyltransferase GPAT

1E-20 - glycerol-3-phosphate activity

Culex quinquefasciatus 7E-015 Lipid transport and metabolism melanogastercatalytic activity transferase O-acyltransferase activi

1 FOR Clathrin-associated protein medium trafficking, secretion, and vesicular transport

chain 6E-45

Culex quinquefasciatus 6E-028 Intracellular carmine - Drosophila melanogaster - ommochrome biosynthetic process - clathrin a

1 FOR Endonuclease 0.47

Culex quinquefasciatus MUS81 Replication, recombination and repair

1 FOR Nicotinic acid phosphoribosyltransferase and metabolism

CG3714 2E-55 nicotinate phosphoribosyltransferase activity||transferase ac

- nicotinatetransferase activity

Culex quinquefasciatus 2E-009 Coenzyme transport - Drosophila melanogastercatalytic activity phosphoribosyltransferase activity

1 FOR Aedes aegypti

F0F1-type ATP synthase, beta subunit synthase-beta - Drosophila melanogaster - hydrogen-exporting ATPase activit

5E-057 Energy production and conversion hydrogen\-exporting activity activity\, phosphorylative mech

ATP 2E-58 catalytic ATPase

hydrolase activity

1 FOR Ubiquitin protein ligase Posttranslational with a checkpoint ubiquitin\-protein ligase ligase activity conjugating protein lig

lethal 6E-54 kinase - Drosophila activity

chaperonesactivity||small

Culex quinquefasciatus 2E-025 RSP5/NEDD4 modification, protein turnover,catalytic melanogaster - ubiquitin-protein ligase

1 FOR 6-phosphogluconolactonase - like protein 6-phosphogluconolactonasestructuralsapiens - pentose-phosphate shunt

Aedes aegypti PGLS: 6E-43 structural molecule activity

3E-046 Carbohydrate transport and metabolism - Homo molecule activity

1 FOR Translation 3E-029 Translation,CG9769 - structure and biogenesis - translationalactivity||translation factor activity\,

ribosomal 4E-36 translation initiation factor initiationfactor

translation - translation initiation ac

Culex quinquefasciatus initiation factor 3, subunit f (eIF-3f)Drosophila melanogastertranslation regulator activity activity\, nucleic fac

1 FOR Glutathione 4E-014 Posttranslational modification, protein E5 - Drosophila melanogaster - glutathione transferase a

Culex quinquefasciatus S-transferase transferase turnover,catalytic activity

chaperones activity||transferase

Glutathione S 5E-22 glutathione transferase transferase activity activity\, transfer

1 FOR Inositol-1,4,5-triphosphate 5-phosphatase (synaptojanin),and vesicular binding family RNA binding - cytoplasm - mRNA

Aedes aegypti trafficking, secretion, INP51/INP52/INP53 binding||nucleic acid binding||binding

1E-11 mRNA binding||RNA -

transport

7E-004 Intracellular quaking related 54B - Drosophila melanogasternucleic acid binding

1 FOR Culex quinquefasciatus

1 FOR Amidases ribosomal structure and biogenesis,-Lipid transport hydrolase activity - lipid partic

6E-45 fatty acid amide hydrolase activity||hydrolase Signal transdu

fatty acid hydrolase activity

amide

Culex quinquefasciatus 8E-027 Translation,CG8839 - Drosophila melanogastercatalytic activity and metabolism, activity\, acting

1 FOR Predicted membrane Function unknown

Culex quinquefasciatus 1E-030 protein 1E-23 19 - Mus musculus

molecular_function

transmembrane protein molecular_function - integral to membrane

1 FOR Transcription initiation Transcriptionsubunit TAF12 factor 12 - Drosophila melanogasterpolymerase II transcription fact

8E-46 general RNA polymeraseregulator activity of transcription, DN

histone acetyltransferase SAGA)

II - regulation

Culex quinquefasciatus 7E-041 factor TFIID, TBP-associated(also component of transcriptionRNAtranscription factor activity||RNA

1 FOR Mitochondrial F1F0-ATP synthase, CG4692f - conversion hydrogen\-exporting ATPase

subunit 3E-47 - hydrogen-exporting activity activity, phospho

hydrolase ATPase

Culex quinquefasciatus 3E-034 Energy production andDrosophila melanogastercatalytic activity activity\, phosphorylative mech

1 FOR 20S proteasome, regulatory subunitlethal (2) 05070 - protein turnover,catalytic endopeptidase activity - proteasome c

beta type PSMB6/PSMB9/PRE3 chaperones

8E-32 endopeptidase activity||peptidase activity

Culex quinquefasciatus 1E-030 Posttranslational modification,Drosophila melanogaster -activity hydrolase activity||hydrolase activity

1 FOR Molecular chaperone PosttranslationalCG10635 - Drosophila melanogaster - 'de novo' protein folding - chaperone binding

5E-22 chaperone binding

chaperones protein binding

Culex quinquefasciatus 8E-016 Prefoldin, subunit 4modification, protein turnover,binding||protein binding||binding

1 FOR 60S ribosomal protein Translation,ribosomal protein L31 - protein norvegicus - protein binding - cytosol - translational e

Culex quinquefasciatus 2E-030 L31 1E-40 biogenesisbinding

ribosomal structure andRattus binding||binding protein binding

1 FOR Metalloexopeptidases transport and metabolism

2E-41 dipeptidase catalytic family)

activity||exopeptidase activity||peptidase - dipe

hydrolase musculus

Culex quinquefasciatus 5E-041 Amino acid CNDP dipeptidase 2 (metallopeptidase M20 activity - Musactivity - cytosolactivity

1 FOR Lipoate-protein ligase CG8446 and metabolism

3E-24

Culex quinquefasciatus 1E-010 ACoenzyme transport - Drosophila melanogaster - lipoyltransferase activity

1 FOR 60s ribosomal protein Translation,Ribosomal structure and -biogenesisstructural of structural constituentmolecule activit

Culex quinquefasciatus 9E-033 L15/L27 1E-37 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein L27A Drosophila melanogaster - translation - structural constitu

1 FOR Uncharacterized conserved protein

Culex quinquefasciatus 0.41 Function unknown

1 FOR Dynein light chain

Aedes aegypti 9E-52 Drosophila catalytic activity microtubule associated complex

melanogaster -hydrolase activity

7E-040 Cell motility Dynein light chain 90F -ATPase activity\, coupled||ATPase activity||nucleoside\-triph

1 FOR 60S ribosomal protein Translation, ribosomal protein L35A Drosophila melanogaster - translation - structural constitu

2E-40 structural constituent molecule activity

ribosome||structural of ribosome

Culex quinquefasciatus 7E-030 L35A/L37 Ribosomal structure and -biogenesisstructural of structural constituentmolecule activit

1 FOR NADH:ubiquinone oxidoreductase, NDUFB6/B17 5E-34

lethal and conversion

- Drosophila melanogaster - mitochondrial electron transport, NADH

catalytic activity

oxidoreductase activity

Culex quinquefasciatus 2E-023 Energy production(2) 35Di subunit NADH dehydrogenase activity||oxidoreductase activity\, acti

1 FOR Predicted C3H1-type General function

Culex quinquefasciatus 0.006 Zn-finger protein prediction only

1 FOR 40S ribosomal protein Translation,Ribosomal structure and Drosophilastructural of structural constituentmolecule activit

Culex quinquefasciatus 1E-046 S16 2E-50 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein S16 - biogenesis melanogaster - translation - structural constitue

1 FOR 60S 2E-021 Translation,Ribosomal structure and biogenesisstructural of structural constituentmolecule activit

Aedes aegypti ribosomal protein L9 5E-44 structural constituent molecule activity

ribosome||structural of ribosome

ribosomal protein L9 - Drosophila melanogaster - translation - structural constituen

1 FOR Culex quinquefasciatus 4E-10

SRY interacting protein 1 - Drosophila melanogaster - olfactory behavior

1 FOR Protein farnesyltransferase, alpha subunit/protein 1E-13 NADH dehydrogenase I,oxidoreductase activity

NDUFB2: NADH dehydrogenase [ubiquinone] 1 alpha subunit

geranylgeranyltransferase type (ubiquinone) activity||NADH dehydro

chaperones beta

Culex quinquefasciatus 0.92 Posttranslational modification, protein turnover,catalytic activity subcomplex subunit 2, mitoch

1 FOR Culex quinquefasciatus 0.00002 molecular_function

molecular_function

CG33493 - Drosophila melanogaster - biological_process - molecular_function - cel

1 FOR Myosin class 0.18 Cytoskeleton

Culex quinquefasciatus I heavy chain

1 FOR Ca2+ release 0.79 Signal transduction

Culex quinquefasciatus channel (ryanodine receptor) mechanisms

Compone

E value of nt Compone E value of Process Process

functional descripto Compone nt second compone descripto Process second

GO # GO rs nt parent parent GO # nt GO rs parent parent GO #



GO:00168870.00E+00 apical cortex xoneme base

GO:00085400.00E+00 proteolysis||cellular protein metabolic process||cellular proton\-transpor

catalytic activity

hydrolase activity

GO:0006508


1.00E-135

GO:0016740 cellular_component GO:0005575

cellular_component catalytic activity

process||primary metabolic

activity

1.00E-135 carbohydrate metabolictransferase GO:0005975 process||metabolic p

1.00E-162

GO:0005388 endoplasmic reticulum||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent proteintransport||cation tr

external encapsulating structure part periplasmic space catalytic activitytri\-valent inorganic cation kinase holoenzym

outer membrane\-bounded

GO:0005783 hydrolase activity

1.00E-162 calcium ion transport||di\-\, GO:0006816

1.00E-168

GO:0003878 external encapsulating structure part periplasmic space catalytic activity

outer membrane\-bounded

GO:0005737 1.00E-168 acetyl\-CoA biosynthetic process||coenzyme biosynthetic process||cofac

transferase activity

cytoplasm||outer membrane\-bounded periplasmic space||external encapsulating structure partGO:0006085

GO:0003674 2.00E-28 cellular_component GO:0005575 2.00E-28 biological_process

cellular_component molecular_function GO:0008150

1.00E-167

GO:0008553
mitochondrial respiratory chain complex I\, complex I\, segmentF(1)||mitochondrial proton\-transporting ATP synthase c

mitochondrial respiratory complex\, catalytic core segment

ATP synthase1.00E-167 proton membrane activity

catalytic hydrolase activity

GO:0015992

1.00E-122

GO:0004473 mitochondrion||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzyme comp

external encapsulating structure part periplasmic space catalytic activity

outer membrane\-bounded

GO:0005739 oxidoreductase activity

GO:0006108

1.00E-122 malate metabolic process||dicarboxylic acid metabolic process||carboxy

GO:0015020 2.00E-36

1.00E-179

GO:0005200 conoid


to plastid GO:0005884 structural molecule activity carboxylase complex||chlorop

structural constituent of cytoskeleton

biotin

1.00E-179 to plastid outer membrane||plastid GO:0007010

1.00E-100

GO:0016791 conoid


GO:00057891.00E-100 biological_process activity

catalytic hydrolase activity

proteasome

1.00E-130

GO:0003988 mitochondrion||nuclear cyclin\-dependent protein kinase holoenzymebeta\-oxidation||fatty acid GO:0006635

external encapsulating structure part periplasmic space complex||cyclin\-dependent proteinprocess||fatty acid metabo

outer membrane\-bounded

GO:00057391.00E-130 fatty acid catalytic activity activity

transferase catabolic kinase holoenzyme comp



1.00E-156

GO:0016887 endoplasmic reticulum||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzym

external encapsulating structure part periplasmic spacetocatalytic activity to temperature stimulus||response to abiotic

outer membrane\-bounded

GO:0005783 1.00E-156 response heat||response GO:0009408

hydrolase activity

1.00E-166

GO:0003746 external encapsulating structure part periplasmic space translation structure activity repair||pedicel mucilage biosyn

outer membrane\-bounded

GO:0005737 1.00E-166
translation DNA

cytoplasm||outer membrane\-bounded periplasmic space||external encapsulating regulationpartGO:0006412 nucleic acid binding

GO:0019841 4.00E-48 region

extracellularextracellular region binding isoprenoid binding

GO:0006869

GO:0005576 4.00E-48 lipid transport||transport||cellular localization||localization

1.00E-152

GO:0003746 mitochondrion||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzymeRNA p

external encapsulating structure part periplasmic space translation regulator activity activity\, nucleic acid binding

outer membrane\-bounded

GO:0005739 translation factor

GO:0006414

1.00E-152
GO:0005524 3.00E-98 external encapsulating structure part 3.00E-98 histidyl\-tRNA aminoacylation||tRNA aminoacylation

outer membrane\-bounded periplasmic space binding

GO:0005737 nucleotide binding

cytoplasm||outer membrane\-bounded periplasmic space||external encapsulating structure partGO:0006427 for protein translatio

GO:0004047 3.00E-94 external encapsulating structure part 3.00E-94 glycine catabolic process||serine family amino acid catabolic process||se

outer membrane\-bounded periplasmic space catalytic activity

GO:0005960 transferase GO:0006546

activity

glycine cleavage complex||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoen

GO:0005515 1.00E-78 conoid


binding protein binding

GO:0006890

proteasome regulatory particle\, base subcomplex||ER proteasome core complex\, beta\-subunit complex||

GO:0004222 4.00E-22 external encapsulating structure part kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzyme comp

outer membrane\-bounded periplasmic space catalytic activity

GO:0005739 hydrolase activity

GO:0006508

mitochondrion||nuclear cyclin\-dependent protein4.00E-22 proteolysis||cellular protein metabolic process||cellular macromolecule m

GO:0004177 2.00E-20 cell fraction soluble GO:0005625 2.00E-20 proteolysis||cellular protein metabolic process||cellular macromolecule m

soluble fraction||cell fraction fraction hydrolase activity

catalytic activity GO:0006508

GO:0042802 1.00E-34 cellular_component GO:0005575 1.00E-34 lipid biosynthetic process||biosynthetic process||metabolic process

cellular_component binding GO:0008610

protein binding

GO:0008691 6.00E-59 fatty acid catabolic process||short\-chain fatty acid metaboli

oxidoreductase activity

short\-chaincatalytic activity GO:0019626

GO:0051082 9.00E-16 external membrane\-bounded organelle||intracellular folding||cellular protein metabolic process||cellular macromolecu

outer membrane\-bounded periplasmic space binding

GO:0005634 protein binding

GO:0006457

nucleus||intracellularencapsulating structure part 9.00E-16 proteinorganelle||outer membrane\-bounded periplasmic space||externa

1.00E-147

GO:0004175
apical cortex xoneme base

GO:0008540 catalytic activity

hydrolase activity

GO:0006510

1.00E-147 ATP\-dependent proteolysis||proteolysis||cellular protein metabolic proce

GO:0004638 7.00E-66

mRNA encapsulating structure cyclin\-dependentspace binding mRNA catabolic process\, nonsense\-mediated dec

outer membrane\-bounded periplasmic protein kinase

GO:0000932 protein binding

GO:0000184

cytoplasmicexternalprocessing body||nuclearpart 4.00E-39 nuclear\-transcribedholoenzyme complex||cyclin\-dependent protein kina

region

GO:0004252 2.00E-51 extracellularextracellular region catalytic activity

hydrolase activity linked

receptor

GO:0005576 2.00E-51 Toll signaling pathway||cell surface GO:0008063 signal transduction||s

GO:0003779 3.00E-03 binding protein binding

GO:0007629

flight behavior||adult locomotory behavior||locomotory behavior||behavio

GO:0003863

1.00E-113 <3\-methyl\-2\-oxobutanoatesmall complex\, spindle polespindle pole body

gamma\-tubulin dehydrogenase (lipoamide) body

gamma\-tubulin small complex\, complex||DNA replicationprocess||fatty acid biosynthetic process||fatty aci

GO:0017086 catalytic activity A complex||DNA

factor GO:0046949

1.00E-113 acyl\-CoA biosynthetic oxidoreductase activity replication factor A comp



GO:0003674 3.00E-35 cellular_component GO:0005575 3.00E-35 biological_process

cellular_component molecular_function GO:0008150

GO:0003674 3.00E-35 cellular_component GO:0005575 3.00E-35 biological_process

cellular_component molecular_function GO:0008150

GO:0003735 3.00E-79 external encapsulating structure part 3.00E-79
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022627 structural constituent of ribosome

GO:0006412

cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

1.00E-140

GO:0004713 integral to plasma membrane||intrinsic to plasma membrane||intrinsic to membrane||coated membrane||membrane

membrane coated membrane

GO:0005887 catalytic activity

transferase GO:0006468

activity

1.00E-140 protein amino acid phosphorylation||post\-translational protein modificat

GO:0005048 1.00E-57 external encapsulating structure part 1.00E-57 cotranslational protein targetingbinding

outer membrane\-bounded periplasmic space binding

GO:0005783 peptide to membrane||protein targeting to mem

GO:0006613

endoplasmic reticulum||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzym

GO:0003674 2.00E-03 external encapsulating structure part 2.00E-03 holoenzyme protein transport||protein transport||cellular holoenzyme com

outer membrane\-bounded kinase intracellular complex||cyclin\-dependent protein kinase protein localizati

GO:0005794

Golgi apparatus||nuclear cyclin\-dependent protein periplasmic space molecular_function GO:0006886

GO:0003674 1.00E-16 molecular_function

biological_process GO:0008150

GO:0008017 1.00E-73 conoid conoid GO:0005875 1.00E-73
binding protein binding

GO:0007349


1.00E-126

GO:0003988 conoid conoid


GO:0016507 catalytic activity

transferase catabolic process||fatty acid metabo

activity

1.00E-126 fatty acid beta\-oxidation||fatty acid GO:0006635

GO:0003674 1.00E-14 cellular_component GO:0005575 1.00E-14 biological_process

cellular_component molecular_function GO:0008150

GO:0003674 4.00E-39 cellular_component GO:0005575 4.00E-39 biological_process

cellular_component molecular_function GO:0008150

GO:0030060 2.00E-95 axoneme aster GO:0005759 2.00E-95 tricarboxyliccatalytic activity

acid cycle||acetyl\-CoAGO:0006099

oxidoreductase reticulum

catabolic process||acetyl\-CoA meta


GO:0003674 3.00E-24 cellular_component GO:0005575 3.00E-24 biological_process

cellular_component molecular_function GO:0008150

GO:0004335 7.00E-67 cell fraction insoluble fraction

GO:0005624 7.00E-67 galactose metabolic activity

membrane fraction||insoluble fraction||cell fraction transferase GO:0006012

activity

catalytic process||hexose metabolic process||monosaccharid

1.00E-103

GO:0003735 cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

external encapsulating structure part periplasmic space structural molecule activity repair||pedicel mucilage kinase

outer membrane\-bounded

GO:0022625 structural constituent of ribosome

1.00E-103
GO:0008553 4.00E-92 axoneme aster GO:0000221 4.00E-92 proton transport||monovalent inorganic cation transport||cation transport

catalytic activity

transfer activity

GO:0015992


external encapsulating structure part 3.00E-63

outer membrane\-bounded periplasmic space

GO:0005730

nucleolus||microsporocyte nucleus||nucleus||intracellular membrane\-bounded organelle||intracellular organelle||outer membrane\-b

GO:0003747 7.00E-78 external encapsulating structure part holoenzyme complex||cyclin\-dependent protein kinase transcription from RNA p

outer membrane\-bounded periplasmic space translation regulator activity activity\, nucleic acid binding

GO:0005829 translation factor

GO:0006414

cytosol||nuclear cyclin\-dependent protein kinase7.00E-78
GO:0008198 6.00E-33 external encapsulating structure part 6.00E-33 cellular iron binding

outer membrane\-bounded periplasmic space encapsulating binding GO:0006879

GO:0008043 ion structure di\-\,

ferritin complex||outer membrane\-bounded periplasmic space||externalion homeostasis||cellular part tri\-valent inorganic cation ho

1.00E-116

GO:0003735 cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

external encapsulating structure part periplasmic space structural molecule activity repair||pedicel mucilage kinase

outer membrane\-bounded

GO:0022627 structural constituent of ribosome

1.00E-116
1.00E-129

GO:0005200 conoid


to plastid GO:0005884 structural molecule activity carboxylase complex||chlorop

structural constituent of cytoskeleton

biotin

1.00E-129 to plastid outer membrane||plastid GO:0007010

1.00E-101

GO:0003735 external encapsulating structure part periplasmic space structural regulationpartGO:0006412

outer membrane\-bounded

GO:0005737 1.00E-101
structural constituent of ribosome

cytoplasm||outer membrane\-bounded periplasmic space||external encapsulatingmolecule activity repair||pedicel mucilage biosyn

1.00E-108

GO:0003735 cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

external encapsulating structure part periplasmic space structural molecule activity repair||pedicel mucilage kinase

outer membrane\-bounded

GO:0022625 structural constituent of ribosome

1.00E-108
GO:0008553 1.00E-94 mitochondrial respiratory chain complex I\, membrane segmentF(1)||mitochondrial proton\-transporting ATP synthase c

mitochondrial respiratory chain complex I\, membrane segment

ATP synthase complex\, catalytic core

catalytic activity

hydrolase activity

GO:0015992


GO:0005515 5.00E-39 external membrane\-bounded organelle||intracellular organelle||outer transcription||regulation of initiation of acetate ca

outer membrane\-bounded periplasmic space binding

GO:0005634 protein binding

GO:0016481

nucleus||intracellularencapsulating structure part 5.00E-39 -negative regulation of membrane\-bounded periplasmic space||externa

GO:0004871 4.00E-82 molecular I\-kappaB activity activity

signal transducer

GO:0043123

+positive regulation of transducer kinase/NF\-kappaB cascade||cytoplasm

GO:0008047 1.00E-19 space||apoplast||extracellular region

region enzyme regulator activity

enzyme activator activity

GO:0006687

extracellularextracellularapoplast GO:0005615 1.00E-19 glycosphingolipid metabolic process||sphingolipid metabolic process||me

GO:0008903 6.00E-34 catalytic isomerase activity

metabolic process activity GO:0008152

1.00E-106

GO:0003924 membrane coated membrane

heterotrimeric G\-protein complex||extrinsic to plasma membrane||extrinsic to membrane||coated membrane||membrane

GO:0005834 catalytic activity

hydrolase activity

signaling pathway||cell surface rece

1.00E-106 G\-protein coupled receptor protein GO:0007186

GO:0005515 9.00E-19 binding protein binding

GO:0006606

protein import into nucleus||protein targeting||intracellular protein transp

GO:0015114 1.00E-89 external encapsulating structure part 1.00E-89 phosphate transport||inorganic

outer membrane\-bounded periplasmic space transporter substrate\-specific transporter activity

GO:0005743 to mitochondrial outer membrane||mitochondrial

GO:0006817

mitochondrial inner membrane||integral to mitochondrial outer membrane||intrinsic activity anion transport||anion transport||ion tran

GO:0005515 7.00E-46 external encapsulating structure part holoenzyme complex||cyclin\-dependent binding kinase transcription from RNA p

outer membrane\-bounded periplasmic space binding

GO:0005829 protein protein

GO:0006414

cytosol||nuclear cyclin\-dependent protein kinase7.00E-46
GO:0003735 2.00E-37 external encapsulating structure part 2.00E-37
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022627 structural constituent of ribosome

GO:0006412

cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

GO:0003729 4.00E-81 external encapsulating structure part holoenzyme complex||cyclin\-dependent acidGO:0006413

outer membrane\-bounded periplasmic space binding

GO:0005829 nucleic protein kinase holoenzyme complex||out

binding

cytosol||nuclear cyclin\-dependent protein kinase4.00E-81
GO:0003735 4.00E-98 external encapsulating structure part 4.00E-98
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

cellular_component GO:0005575 2.00E-78

cellular_component

membrane coated membrane GO:0016021 1.00E-13 protein targeting||intracellular protein transport||proteinactivity

integral to membrane||intrinsic to membrane||coated membrane||membrane substrate\-specific transporter transport||cellula

transporter activity GO:0006605

1.00E-167

GO:0005391 nucleus||intracellularencapsulating structure part periplasmic spacetocatalytic activity

external membrane\-bounded organelle||intracellular organelle||outer membrane\-boundedto external stimulus||respon

outer membrane\-bounded

GO:0005634 stimulus||response

GO:0009612

1.00E-167 response mechanicalhydrolase activity periplasmic space||externa

GO:0003735 7.00E-78 external encapsulating structure part 7.00E-78
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022627 structural constituent of ribosome

GO:0006412

cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

GO:0003674 7.00E-17 cellular_component GO:0005575 7.00E-17 biological_process

cellular_component molecular_function GO:0008150

GO:0003674 2.00E-07 cellular_component GO:0005575 2.00E-07 biological_process

cellular_component molecular_function GO:0008150

GO:0003924 4.00E-54 external membrane\-bounded organelle||intracellular organelle||outer membrane\-bounded periplasmic space||externa

outer membrane\-bounded periplasmic space catalytic activity

GO:0005634 hydrolase activity

GO:0000079

nucleus||intracellularencapsulating structure part 4.00E-54 regulation of cyclin\-dependent protein kinase activity||regulation of prot



external encapsulating structure part kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzyme comp

outer membrane\-bounded periplasmic space catalytic activity

GO:0005739 hydrolase activity

GO:0006508

GO:0004222 1.00E-09 mitochondrion||nuclear cyclin\-dependent protein1.00E-09 proteolysis||cellular protein metabolic process||cellular macromolecule m

catalytic in hydrolase activity

camera\-type eye||regulation of sevenless signa


external encapsulating structure part 4.00E-31
outer membrane\-bounded periplasmic space catalytic activity

GO:0005783 transferase GO:0006486

activity

GO:0000026 4.00E-31 endoplasmic reticulum||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzym

external encapsulating structure electron transfer flavoprotein complex||electron transfer flavoprotein complex||nuclear

outer membrane\-bounded periplasmic space binding

GO:0005788 ion binding GO:0006457

GO:0005509 2.00E-64 endoplasmic reticulum lumen||mitochondrial part 2.00E-64 protein folding||cellular protein metabolic process||cellular macromolecu

cellular_component GO:0005575 5.00E-07 biological_process

GO:0003674 5.00E-07 cellular_component molecular_function GO:0008150

external encapsulating structure part 2.00E-83
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

GO:0003735 2.00E-83 cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

cellular_component GO:0005575 5.00E-47 glycolysis||glucose catabolic process||hexose catabolic process||monos

GO:0004396 5.00E-47 cellular_component transferase GO:0006096

catalytic activity activity



GO:0003735 5.00E-58 cytosolic ribosomal subunit||GARP complex||plasma membrane\-derived thylakoid DNA repair||pedicel mucilage biosyn

centromere\-specific nucleosome
GO:0005763 5.00E-58


membrane||mitochondrial small ribo

structural regulation of GO:0006412

GO:0003735 3.00E-77 external encapsulating structure part 3.00E-77
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

GO:0003674 2.00E-10 cellular_component GO:0005575 2.00E-10 biological_process

cellular_component molecular_function GO:0008150

GO:0003674 1.00E-12 cellular_component GO:0005575 1.00E-12 biological_process

cellular_component molecular_function GO:0008150

GO:0000049 1.00E-57 external encapsulating structure part 1.00E-57 -negative regulation periplasmic space||external encapsulating structure

outer membrane\-bounded periplasmic space binding

GO:0017101 nucleic acidGO:0001937

binding

aminoacyl\-tRNA synthetase multienzyme complex||outer membrane\-bounded of endothelial cell proliferation||negative regulation

GO:0003674 4.00E-54 cellular_component GO:0005575 4.00E-54 biological_process

cellular_component molecular_function GO:0008150

GO:0003735 2.00E-71 external encapsulating structure part 2.00E-71
outer membrane\-bounded periplasmic space structural structure of DNA

GO:0005737 structural constituent of ribosome

cytoplasm||outer membrane\-bounded periplasmic space||external encapsulatingmolecule activity repair||pedicel mucilage biosyn

GO:0003735 5.00E-67 external encapsulating structure part 5.00E-67
outer membrane\-bounded periplasmic space structural molecule activity

GO:0005730 structural regulation of ribosome

GO:0006414

nucleolus||microsporocyte nucleus||nucleus||intracellular membrane\-bounded organelle||intracellular organelle||outer membrane\-b

GO:0003824 1.00E-36 external encapsulating structure part 1.00E-36 metabolic process activity

outer membrane\-bounded periplasmic space catalytic

GO:0005777 GO:0008152

peroxisome||microbody||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzy

GO:0008553 1.00E-62 mitochondrial proton\-transporting ATPcomplex\, coupling factor F(o)||mitochondrial proton\-transporting ATP synthase

mitochondrial proton\-transporting proton transport||monovalent inorganic cation transport||cation transport

ATP synthase synthase complex catalytic activity


GO:0003674 1.00E-20 cellular_component GO:0005575 1.00E-20 biological_process

cellular_component molecular_function GO:0008150

external encapsulating structure part 1.00E-36 neurotransmitter membrane||cytoplasmic synaptic transmission||determ

to Golgi transport vesicle periplasmic space transporter activity

GO:0030125 neurotransmitter transporter activity

GO:0007269

GO:0005326 1.00E-36 clathrin vesicle coat||ERouter membrane\-boundedmembrane||coated vesiclesecretion||neuromuscular vesicle membrane||cytoplasm

cellular_component GO:0005575 2.00E-03
cellular_component molecular_function GO:0046716

external encapsulating structure part holoenzyme complex||cyclin\-dependent protein kinase holoenzyme complex||out

outer membrane\-bounded periplasmic space catalytic activity

GO:0005829 isomerase activity

GO:0006457

GO:0003755 3.00E-78 cytosol||nuclear cyclin\-dependent protein kinase3.00E-78 protein folding||cellular protein metabolic process||cellular macromolecu



GO:0003735 1.00E-62 external encapsulating structure part 1.00E-62
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022627 structural constituent of ribosome

GO:0006412

cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

GO:0003746 4.00E-79 external encapsulating structure part 4.00E-79 cyclin\-dependent protein kinaseactivity activity\, nucleic acid binding p

outer membrane\-bounded periplasmic space translation regulator regulation of transcription from RNA

GO:0005853 translation factor

GO:0006414

eukaryotic translation elongation factor 1 complex||nuclear
GO:0008553 8.00E-63 axoneme aster GO:0000220 8.00E-63 mitotic spindle electronhydrolaseflavoprotein complex||cytoplasmic DNA

catalytic activity

transfer activity

GO:0007052


GO:0003983 2.00E-63 external encapsulating structure part 2.00E-63 UDP\-glucose metabolic process||glucose metabolic process||hexose m

outer membrane\-bounded periplasmic space catalytic activity

GO:0005737 transferase activity

cytoplasm||outer membrane\-bounded periplasmic space||external encapsulating structure partGO:0006011



external encapsulating structure part 3.00E-61
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022627 structural constituent of ribosome

GO:0006412

GO:0003735 3.00E-61 cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

external encapsulating structure part 6.00E-11 tryptophan catabolic activity to kynurenine||tryptophan catabolic proces

outer membrane\-bounded periplasmic space catalytic process

GO:0005737 hydrolase activity

GO:0004061 6.00E-11 cytoplasm||outer membrane\-bounded periplasmic space||external encapsulating structure partGO:0019441

external encapsulating structure part 2.00E-39
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

GO:0003735 2.00E-39 cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

GO:0004794 2.00E-16 catalytic process||branched chain family amino acid metabo

lyase G

isoleucine metabolic activity activity O:0006549

external encapsulating structure part kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzyme comp

outer membrane\-bounded periplasmic space

GO:0005739

mitochondrion||nuclear cyclin\-dependent protein9.00E-03



GO:0008146 1.00E-05 cellular_component GO:0005575 1.00E-05 biological_process activity

cellular_component activity

catalytic transferase GO:0008150

GO:0003924 5.00E-69 external encapsulating GO:0005770 periplasmic space to lysosome hydrolase activity transport||vacuolar transpo

outer membrane\-bounded protein kinase catalytic activity

cyclin\-dependent transport||lysosomal

GO:0008333

late endosome||endosome||nuclearstructure part 5.00E-69 endosomeholoenzyme complex||cyclin\-dependent protein kinase holoen

GO:0004108 1.00E-79 axoneme aster GO:0005759 1.00E-79 carbohydrate vesicle coat||endoplasmic reticulum process||metabolic

catalytic activity

process||primary metabolic

activity


GO:0005515 8.00E-37 external encapsulating structure part 8.00E-37 ER\-associated protein catabolic process||proteasomal ubiquitin\-depen

outer membrane\-bounded periplasmic space binding

GO:0005783 protein binding

GO:0030433

endoplasmic reticulum||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzym

GO:0003735 9.00E-55 external encapsulating structure part 9.00E-55
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

GO:0004467 2.00E-53 cellular_component GO:0005575 2.00E-53 long\-chain fatty acidactivity activity

cellular_component ligase GO:0001676

catalytic metabolic process||fatty acid metabolic process||m

GO:0003735 2.00E-63 external encapsulating structure part 2.00E-63
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn



network transportmembrane\-bounded periplasmic space vesicle||cytoplasmic membrane\-bounded vesicle||cytoplasm

outer vesicle||clathrin\-coated vesicle||coated catalytic activity

GO:0030140 hydrolase activity

GO:0048477

GO:0003924 1.00E-66 trans\-Golgiexternal encapsulating structure part 1.00E-66 oogenesis||female gamete generation||gamete generation||sexual repro



GO:0003735 9.00E-65 external encapsulating structure part 9.00E-65
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022627 structural constituent of ribosome

GO:0006412

cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

GO:0003674 8.00E-10 cellular_component GO:0005575 8.00E-10 biological_process

cellular_component molecular_function GO:0008150

GO:0016209 3.00E-63 region

extracellularextracellular region apoptosis||induction GO:0006917

GO:0005576 3.00E-63 induction of antioxidant activity of programmed cell death||positive regu

GO:0004703 6.00E-63 external encapsulating structure part 6.00E-63 protein amino acid phosphorylation||post\-translational protein modificat

outer membrane\-bounded periplasmic space catalytic space||external encapsulating structure part

GO:0031588

AMP\-activated protein kinase complex||outer membrane\-bounded periplasmic activity activity

transferase GO:0006468

GO:0005544 1.00E-42 cellular_component GO:0005575 1.00E-42 biological_process

cellular_component binding lipid bindingGO:0008150

GO:0003735 9.00E-36 external encapsulating structure part 9.00E-36
outer membrane\-bounded periplasmic space structural molecule activity

GO:0022627 structural constituent of ribosome

GO:0000022

cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein kinase

GO:0016887 2.00E-56 external encapsulating structure part 2.00E-56 response tocatalytic activity to temperature stimulus||response to abiotic

outer membrane\-bounded periplasmic space heat||response

GO:0005783 hydrolase activity

GO:0009408

endoplasmic reticulum||nuclear cyclin\-dependent protein kinase holoenzyme complex||cyclin\-dependent protein kinase holoenzym

GO:0003899 4.00E-45 axoneme aster GO:0005665 4.00E-45 transcriptioncatalytic activity

from RNA polymerase activity

transferase II promoter||transcription\, DNA\-dep


GO:0005515 3.00E-58 external encapsulating structure part 3.00E-58 protein encapsulating structurebinding

outer membrane\-bounded periplasmic space binding

GO:0005737 protein partGO:0006464

cytoplasm||outer membrane\-bounded periplasmic space||external modification process||cellular protein metabolic process||cellular

GO:0004222 7.00E-17 cell projection

neuron projection

GO:0030425 7.00E-17 open tracheal system development||gametophyte development||multice

dendrite||neuron projection||cellprojection hydrolase activity

catalytic activity GO:0007424



external encapsulating structure part 4.00E-29 protein encapsulating structurebinding

outer membrane\-bounded periplasmic space binding

GO:0005737 protein partGO:0022417

GO:0003713 4.00E-29 cytoplasm||outer membrane\-bounded periplasmic space||external maturation via protein folding||protein maturation||cellular protein

space||apoplast||extracellular region

region catalytic activity

hydrolase activity

GO:0006508

GO:0008234 1.00E-30 extracellularextracellularapoplast GO:0005615 1.00E-30 proteolysis||cellular protein metabolic process||cellular macromolecule m



cellular_component

GO:0003674 4.00E-21 cellular_component molecular_function

GO:0005575 4.00E-21 biological_process GO:0008150





external encapsulating structure part 1.00E-20 phospholipid biosynthetic process||membrane membrane||mitochondria

outer membrane\-bounded periplasmic space catalytic activity

GO:0005741 to mitochondrial outer lipid

activity

GO:0004366 1.00E-20 mitochondrial outer membrane||integral to mitochondrial outer membrane||intrinsic transferase GO:0008654 biosynthetic process

external encapsulating structure part 8.00E-35 transport||cellular membrane||cytoplasmic

to Golgi transport vesicle periplasmic space catalytic activity

GO:0030125 transferase GO:0006810

activity

clathrin vesicle coat||ERouter membrane\-boundedmembrane||coated vesicle localization||localization vesicle membrane||cytoplasm



GO:0004516 8.00E-33 external encapsulating structure part holoenzyme complex||cyclin\-dependent

outer membrane\-bounded periplasmic space oxidative stress||response to chemical stimulus||response t

GO:0005829 transferase GO:0006979

activity

cytosol||nuclear cyclin\-dependent protein kinase8.00E-33 response tocatalytic activity protein kinase holoenzyme complex||out

GO:0008553 2.00E-58 mitochondrial respiratory chain complex I\, membrane segmentF(1)||mitochondrial proton\-transporting ATP synthase c

mitochondrial respiratory chain complex I\, membrane segment

ATP synthase complex\, catalytic core

catalytic activity

hydrolase activity

GO:0015992


GO:0004842 9.00E-42 intracellularintracellular catalytic activity activity

ligase GO:0006464

GO:0005622 9.00E-42 protein modification process||cellular protein metabolic process||cellular

GO:0005198 3.00E-42 external cytoskeleton||cytoskeleton||intracellular non\-membrane\-bounded organelle||intracellular process||metabolic p

outer membrane\-bounded periplasmic space structural molecule activity

GO:0005874 GO:0005975

microtubule||cortical encapsulating structure part 3.00E-42 carbohydrate metabolic process||primary metabolicorganelle||outer mem

GO:0003743 4.00E-36 external encapsulating structure part 4.00E-36
outer membrane\-bounded periplasmic space translation translation signaling involved in postnatal olfacto

GO:0005852 kinase holoenzyme

GO:0006413

eukaryotic translation initiation factor 3 complex||nuclear cyclin\-dependent proteinregulator activity activity\, nucleic acid binding

GO:0004364 2.00E-20

GO:0003729 7.00E-07



GO:0017064 2.00E-25

GO:0003674 4.00E-14 molecular_function

biological_process GO:0008150

GO:0016251 8.00E-46 external membrane\-bounded organelle||intracellular organelle||outer membrane\-bounded periplasmicfactor activity

outer membrane\-bounded periplasmic space of transcription\, polymerase II transcription space||externa

GO:0005634 regulator activity

GO:0006355

nucleus||intracellularencapsulating structure part 8.00E-46 ®ulation transcriptionRNA DNA\-dependent||gene conversion at matin

GO:0008553 3.00E-47 mitochondrial proton\-transporting ATPcomplex\, coupling factor F(o)||mitochondrial proton\-transporting ATP synthase

mitochondrial proton\-transporting proton transport||monovalent inorganic cation transport||cation transport

ATP synthase synthase complex catalytic activity


GO:0004175 2.00E-21 external membrane\-bounded organelle||intracellular organelle||outer membrane\-bounded periplasmic space||externa

outer membrane\-bounded periplasmic space catalytic activity

GO:0005634 hydrolase protein

GO:0043161

nucleus||intracellularencapsulating structure part 2.00E-21 proteasomal ubiquitin\-dependent activity catabolic process||ubiquitin\-d

GO:0051087 5.00E-22 external encapsulating structure part 5.00E-22 'de space binding

outer membrane\-bounded part||nuclear cyclin\-dependentprotein binding

GO:0016272 protein folding||cellular protein metabolic proce

GO:0006458

prefoldin complex||vesicle coat||cytoplasmic vesicleperiplasmicnovo' protein folding||protein kinase holoenzyme complex||cyclin\-de

GO:0005515 1.00E-40 external encapsulating structure part holoenzyme complex||cyclin\-dependent binding kinase transcription from RNA p

outer membrane\-bounded periplasmic space binding

GO:0005829 protein protein

GO:0006414

cytosol||nuclear cyclin\-dependent protein kinase1.00E-40
GO:0016805 2.00E-41 external encapsulating structure part holoenzyme complex||cyclin\-dependent protein kinase holoenzyme complex||out

outer membrane\-bounded periplasmic space catalytic activity

GO:0005829 hydrolase activity

GO:0006508

cytosol||nuclear cyclin\-dependent protein kinase2.00E-41 proteolysis||cellular protein metabolic process||cellular macromolecule m

catalytic activity

transferase GO:0009107

activity

lipoate biosynthetic process||lipoic acid biosynthetic process||lipoic acid

external encapsulating structure part 1.00E-37
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

GO:0003735 1.00E-37 cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn



conoid conoid GO:0005875 9.00E-52 microtubule\-based movement||microtubule\-based membrane||cyanell

catalytic activity

hydrolase activity

GO:0007018

GO:0042623 9.00E-52
external encapsulating structure part 2.00E-40
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

GO:0003735 2.00E-40 cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

flagellin\-based flagellum outer membrane

intrinsic complex I||lysosomal proton\-transporting V\-type ATPase complex||lysosomal proton\-transporting

GO:0005747 5.00E-34 rod catalytic activity

transport\, NADH to ubiquinone||mitochondrial e

GO:0006120

GO:0003954 5.00E-34


external encapsulating structure part 2.00E-50
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022627 structural constituent of ribosome

GO:0006412

GO:0003735 2.00E-50 cytosolic small ribosomal subunit||small ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent proteinbiosyn

external encapsulating structure part 5.00E-44
outer membrane\-bounded periplasmic space structural regulation of DNA

GO:0022625 structural constituent of ribosome

GO:0006412

GO:0003735 5.00E-44 cytosolic large ribosomal subunit||large ribosomal subunit||polysomal ribosome||ribosome||nuclear cyclin\-dependent protein biosyn

catalytic activity

oxidoreductase activity

GO:0042048

olfactory behavior||chemosensory behavior||response to chemical stimu

flagellin\-based flagellum outer membrane

intrinsic complex I||lysosomal proton\-transporting V\-type ATPase complex||lysosomal proton\-transporting

GO:0005747 1.00E-13 rod catalytic activity

transport\, NADH to ubiquinone||mitochondrial e

GO:0006120

GO:0008137 1.00E-13
cellular_component GO:0005575 2.00E-05 biological_process

GO:0003674 2.00E-05 cellular_component molecular_function GO:0008150

Best Best Best Best

E value of match to match to match to match to

process CDD All CDD PFAM SMART COG General

GO database E value domains database E value database E value database E value class

RAP1 1E-004 RAP1 4E-005 CobN, Cobalamin PRK08691 PRK12323 | and related Mg

2E-004 Coenzyme metabolism

RAP1 1e-004| CobN 5e-004| PRK07003 0.013| Herpes_BLLF1 | PRK07764 | biosynthesis| protein CobNPRK12372 | PA

0.00E+00 RPT1 1E-134 AAA 2E-057 AAA 7E-014 RPT1, 2e-055| hflB 8e-050| COG1223 2e-038| AAA 6e-012

1E-134 Posttranslational modification, protei

RPT1 e-134| PRK03992 e-116| SpoVK 7e-064| AAA 7e-057| HflB ATP-dependent 26S proteasome regulatory subunit

1.00E-135 GlgB 7E-039 Alpha-amylase0.41 Aamy 0.38 GlgB, 1,4-alpha-glucan branching enzyme

PulA 0.021| PRK03705 0.036|

GlgB 7e-039| PRK12313 2e-025| PRK05402 4e-025| PRK12568 9e-015|2E-039 Carbohydrate transport and metabo

1.00E-162 MgtA 4E-068 Cation_ATPase_C

6E-035 MA 0.96 MgtA, Cation 1E-068 ATPase ion transport and metaboli

transport Inorganic

MgtA 4e-068| Cation_ATPase_C 2e-034| PRK10517 1e-024| ZntA 2e-019| zntA 8e-014| PRK10671 5e-013| KdpB 4e-0

1.00E-168 SucD 9E-032 Ligase_CoA 1E-023 PRK05678 5e-018| GltA 5e-013| PRK06224 synthetase, alpha subunit conversion

SucD 9e-032| Ligase_CoA 5e-023| PIPKc 3E-032 Energy

0.29 SucD, Succinyl-CoA 3e-010| production and

2.00E-28 IlvC 0.27 GcvT

IlvC | LON | LON | 0.11 0.082 Amino acid

IlvC, Ketol-acid reductoisomerase transport and metabolism

1.00E-167 PRK09280 1E-163 ATP-synt_ab 2E-061 AAA 5E-005 AtpD, F0F1-type ATP synthase, beta subunit conversion

1E-155 Energy production and

PRK09280 e-163| AtpD e-154| F1-ATPase_beta e-138| atpB e-136| PRK12597 e-121| ATP-synt_ab 7e-061| FliI 1e-048

1.00E-122 Malic_M 2E-078 Malic_M 5E-079 SfcA, PRK12862 3e-023| PRK12861 2e-017| COG4938 0.0

3E-061

Malic_M 2e-078| SfcA 1e-060| malic 6e-044| PRK07232 3e-023| Malic enzyme Energy production and conversion

UDPGT 9E-015 UDPGT 9e-015|UDPGT 2E-015 JHBP 0.14

1.00E-179 ACTIN 1E-136 Actin 1E-136 ACTIN 1E-138 Actin and | PRK06940 |Cytoskeleton

5E-091

ACTIN e-136| Actin e-135| ACTIN e-135| COG5277 2e-090| DUF248related proteins

1.00E-100 COG5329 2E-063 Syja_N 2E-026

COG5329 2e-063| Syja_N 9e-026| 5E-064 Signal transduction mechanisms

Phosphoinositide polyphosphatase (Sac family)

1.00E-130 thiolase 1E-108 Thiolase_N 9E-048 PTX 0.27 PaaJ, 9e-078|1E-061 Lipid metabolism

PRK09050 8e-075| PRK06445 1e-072| PRK0

thiolase e-108| PRK06845 e-102| PRK09051 6e-087| PRK05790 Acetyl-CoA acetyltransferase

AF-4 1E-004 AF-4 3E-005 VWD 3E-006 RNA-binding 0.005| of the Puf family, 0.011| Secretin_N_2

0.006 Translation, ribosomal structure and

AF-4 1e-004| VWD 2e-004| Herpes_gp2 0.002| SSP160 0.002| DUF601 protein DNA_pol_viral_N translational represso

1.00E-156 HSP70 1E-106 HSP70 1E-106 RIBOc 0.39 DnaK, Molecular chaperone

5E-076 Posttranslational modification, protei

HSP70 e-106| dnaK e-101| DnaK 2e-075| dnaK 3e-075| hscA 4e-060| hscA 3e-030| FGGY_C | PRK12704 | Serine_ric

1.00E-166 PRK07560 1E-057 EFG_IV 3e-053| UAS 0.17 FusA, eEF2_snRNP_like_II factors (GTPases) 7e-023| EF

9E-054 Translation, PRK12740

PRK07560 1e-057| FusA 7E-007 aeEF2_snRNP_like_IV 9e-037|Translation elongation5e-035|ribosomal structure and

4.00E-48 VWD 6E-005 VWD 2E-004 VWD

VWD 6e-005| VWD 7e-004| DUF953 | C8 | ComFC | 0.22 General function prediction only

7E-007 ComFC, Predicted amidophosphoribosyltransferases

1.00E-152 PRK00049 1E-136 GTP_EFTU 8E-057 PROF 0.33 TufB, GTPases - translation elongation factors 1e-063| and

e-118| Translation, ribosomal

PRK00049 e-136| PRK12735 e-133| PRK12736 e-127| TufB e-125| tufA 1E-125EF_Tu e-100| PRK12317 structureGTP

3.00E-98 HisS 2E-052 tRNA-synt_2b3E-025 MCM 0.10 HisS, Histidyl-tRNA synthetase

5E-053 Translation, ribosomal structure and

HisS 2e-052| HisRS-like_core 3e-048| PRK12420 7e-040| hisS 1e-038| HisZ 1e-024| tRNA-synt_2b 1e-024| hisZ 8e-02

3.00E-94 GcvT 5E-067 GCV_T 1E-054 GCV_T_C 2e-014| COG0354 8e-007| SoxG and metabolism

cleavage system T transport |

GcvT 5e-067| gcvT 3e-065| GCV_T 4e-054| dmdA 3e-017| GcvT, Glycine1E-067 Amino acidprotein (aminomethyltrans

1.00E-78 Coatomer_E 1E-077 Coatomer_E 4E-078 TPR 0.029 Uncharacterized proteinFunction unknown

Coatomer_E 1e-077| TPR 0.018| COG1729 0.031| COG4783 | PilF | 0.009 conserved in bacteria

4E-016

4.00E-22 Peptidase_M16 Peptidase_M161E-016 REC 5E-014 General function prediction only

Peptidase_M16 4e-016| PqqL 2e-013| COG3437 | 0.37 PqqL, Predicted Zn-dependent peptidases

2.00E-20 PepN 0.21 PepN | POPLD 0.41 PB1 0.064 N

0.93 PepN, Aminopeptidase Amino acid transport and metabolism

1.00E-34 COG3319 5E-021 Thioesterase 6E-018 Thioesterase 1E-021 of type I polyketide synthases or non

domains Secondary

COG3319 5e-021| Thioesterase 2e-017| PRK10252 4e-007| GrsT 1e-005| PRK12467 0.009| metabolites biosynthesis

6.00E-59 FadB 3E-079 3HCDH_N 2e-067| RIO 0.12 FadB, 3-hydroxyacyl-CoA 5e-060| PRK07530 1e-058| PRK0

8E-080 Lipid metabolism

FadB 3e-079| PRK08268 3E-046 PRK07819 2e-064| PRK09117 4e-063| PRK05808 dehydrogenase

9.00E-16 SANT 0.001 Myb_DNA-binding Myb_DNA-binding 0.007| RSC8RSC8, RSC |chromatin remodeling structure and dynamics /

SANT 0.001| SANT 0.004|0.002 SANT 4E-005 0.037| TEA 0.011 Chromatin complex subunit RSC8

1.00E-147 RPT1 1E-092 AAA 6e-076| AAA 2E-009 RPT1, ATP-dependent 26S proteasome modification, protei

4E-093 Posttranslational 2e-021| PRK0419

RPT1 1e-092| PRK039922E-025 SpoVK 1e-032| HflB 2e-028| hflB 6e-025| AAA 6e-025| COG1223regulatory subunit

5E-042

SAICAR_synt_Ade AIRC 1E-036 CLa 0.17 PurE, SAICAR_synt 5e-022| PurEtransportPurCmetabolism

7E-016 Nucleotide 2e-015| and 1e-013| P

SAICAR_synt_Ade5 5e-042| AIRC 4e-036| SAICAR_synt 1e-023|Phosphoribosylcarboxyaminoimidazole (NCAIR) muta

4.00E-39 CDC39 0.028 GAL11 0.19 CDC39, Cell |0.008 control |protein, negative regulator of tr

FliJ | Cell COG3264

CDC39 0.028| PRK11281 0.093| MukB | PRK03635 | mukB | PRK08316divisionGAL11 division and |chromosome partiti

2.00E-51 Tryp_SPc 1E-054 Trypsin 9E-042 Tryp_SPc 7E-055 Secreted trypsin-like 5e-004| COG3591 0.006|

DUF316 Posttranslational modification, protei

Tryp_SPc 1e-054| Tryp_SPc 6e-053| Trypsin 3e-041| COG5640 9e-025| 3E-025 serine protease

3.00E-03 OspD 0.33 OspD

OspD | COG4886 | 0.093 SynN 0.16 Function unknown

0.34 Leucine-rich repeat (LRR) protein

3E-068

1.00E-113 TPP_E1_PDC_ADC_ E1_dh 6E-054 Glyco_10 0.60 2e-053| TPP_TK 6e-011| TPP_enzymes 2e-007| COG3959

3E-067 Energy production and complex, de

TPP_E1_PDC_ADC_BCADC 3e-068| AcoA 9e-067| E1_dhAcoA, Pyruvate/2-oxoglutarate dehydrogenaseconversion

PRK07003 0.005 Herpes_BLLF1 0.009 CobN, 0.034| PRK12373 0.044| PRK08853 0.044| PRK0869

0.003 Coenzyme metabolism

PRK07003 0.005| CobN 0.009| PRK12323 0.025| Herpes_BLLF1 Cobalamin biosynthesis protein CobN and related Mg

3.00E-35 XendoU 5E-036 XendoU

XendoU 5e-036| DUF5061E-036| 0.47 Translation, ribosomal structure and

LeuS, Leucyl-tRNA synthetase

3.00E-35 XendoU 5E-036 XendoU

XendoU 5e-036| DUF5061E-036| 0.47 Translation, ribosomal structure and

LeuS, Leucyl-tRNA synthetase

2

3.00E-79 Ribosomal_S2 E-058 Ribosomal_S2 E-059 DM11

5 0.79 RpsB, rps2 0.008| rpsBTranslation, ribosomal structure

7E-038 S2

Ribosomal_S2 2e-058| rps2P 3e-044| RpsB 2e-037| rpsB 1e-008|Ribosomal protein0.021| aceF | rplL | DUF447 | and

1.00E-140 PTKc 5E-091 Pkinase_Tyr 3E-081 Pkinase_Tyr 4E-081 TyrKc 4e-079| PTKc_FGFR1 3e-070| PTKc_RET 5e-070|/ PT

PTKc 5e-091| PTKc_FGFR 3e-082|TyrKc 6E-019 protein function

1e-080| SPS1, Serine/threonineGeneral kinase prediction only Sig

1.00E-57 TRAP_alpha 2E-079 TRAP_alpha 5E-080 ZntA, TadB 0.011 Inorganic

TRAP_alpha 2e-079| ZntA 0.037| PRK08434 | COG1361 | scpA |Cation |transport ATPase ion transport and metaboli

2.00E-03 PRK01156 0.016 DUF1669 0.025 PRK02224 0.19 | Myosin_tail_1 | COG4717 | Smc Herpes_BLLF1 |

0.077 General function prediction

PRK01156 0.016| DUF1669 0.090| Glyco_18 | COG1579 Zn-ribbon protein, possibly nucleic|acid-binding only

1.00E-16 DUF525 1E-044 DUF525 4E-045

DUF525 1e-044| apaG 8e-030| ApaG 3e-024| 8E-025 protein affecting Mg2+/Co2+ transp

ApaG, UncharacterizedInorganic ion transport and metaboli

1.00E-73 CAP_GLY 4E-023 CAP_GLY 1E-023 PsiA

CAP_GLY 4e-023| NIP100 5e-016| STI | COG4717 | 1E-016 Cell division and chromosome partiti

0.63 NIP100, Dynactin complex subunit involved in mitotic spindl

1.00E-126 thiolase 3E-071 Thiolase_C 5E-037 PaaJ, Acetyl-CoA acetyltransferase

3E-037 Lipid PRK06205

thiolase 3e-071| fadI 7e-068| PRK08170 4e-056| PRK09268 2e-055| PRK06445 5e-045|metabolism 3e-043| fadA 3e-0

1.00E-14 CDC45 0.16 CDC45

CDC45 | RpoD | 0.044 HOLI 0.17 Transcription

0.14 RpoD, DNA-directed RNA polymerase, sigma subunit (sigm

4.00E-39 MRP_L46 2E-037 NUP 0.68 MutT, NTP pyrophosphohydrolases including oxidative dam

0.019 DNA replication, recombination, and

MRP_L46 2e-037| Nudix_Hydrolase 0.002| Ap4A_hydrolase_plant_like 0.034| MutT 0.063| PRK04140 | Nudix_Hydrola

1E-102

2.00E-95 MDH_glycosomal_ Ldh_1_C 1E-041 SET 1e-081| LDH_MDH 6e-048| Mdh 8e-045| Ldh_1_C 5e-041| LDH-lik

3E-045 Energy production and conversion

MDH_glycosomal_mitochondrial e-102| PRK050860.70 Mdh, Malate/lactate dehydrogenases

3.00E-24 DUF647 2E-034 DUF647

DUF647 2e-034| 7E-035 NTR 0.49

7.00E-67 GalK 2E-065 GHMP_kinases_C

2e-062| GalK, Galactokinase

PRK00555 3e-040| GHMP_kinases_C 1e-011

GalK 2e-065| PRK05322 3E-012 PRK05101 1e-057| PRK03817 5e-048|8E-066 Carbohydrate transport and metabo

1.00E-103 rpl18p 1E-018 Ribosomal_L18p

2E-013 RplR, Ribosomal protein Fe-ADH | PtsA |

7E-007 Translation, ribosomal structure and

rpl18p 1e-018| Ribosomal_L18p 9e-013| Ribosomal_L18_L5e 4e-012| RplR 2e-006|L18

4.00E-92 vATP-synt_E 1E-045 vATP-synt_E 3E-046 NtpE, Archaeal/vacuolar-type H+-ATPase and conversion

8E-016

vATP-synt_E 1e-045| NtpE 3e-015| PRK03963 2e-009| PRK02292 0.001| ArpD | Energy production subunit E

Brix 1E-033 IMP4 4E-034 btg1 0.11 IMP4, Predicted exosome subunit/U3 small nucleolar ribonu

1E-028 PRK11621

Brix 1e-033|Brix 4e-028| PRK03972 5e-006| BRX1 0.008| DUF859 | PRK10436 |Translation, |ribosomal structure and

7.00E-78 EF1_GNE 5E-029 EF1_GNE 5e-028| DM10 0.37 EFB1, Translation ef1B 0.004| Gst ribosomal structure and

6E-016 Translation, EF-1beta

EF1_GNE 5e-029| EF1B 1E-029 EFB1 2e-015| GST_C_Delta_Epsilon 0.004|elongation factor 0.009| GST_C_1 0.067|

6.00E-33 Euk_Ferritin 2E-019 2e-019| 2E-005 LamNT 0.067 CitA, | PRK08270 |

0.92 Signal transduction mechanisms

Euk_FerritinFerritin Ferritin 1e-012| Ferritin 8e-005| PRK06701 Signal transduction histidine kinase regulating citrate/m

1.00E-116 rps5p 2E-061 Ribosomal_S5 E-021 TR_THY

1 0.038 RpsE, Ribosomal_S5_C S5

5E-042 Translation, ribosomal

rps5p 2e-061| RpsE 2e-041| Ribosomal_S5 4e-021| rpsE 7e-018| Ribosomal protein 2e-017| rps5 4e-013|structure and

1.00E-129 Actin 5E-095 Actin 2E-095 ACTIN 7E-097 Actin 1E-061 Cytoskeleton

Actin 5e-095| ACTIN 6e-095| ACTIN 2e-093| COG5277 3e-061| and related proteins

1.00E-101 RpsC 9E-039 Ribosomal_S3_C

4E-019 KH Ribosomal_S3_C 2e-018| protein S3

3E-039 Translation, 6e-007| archeal_30S_S

RpsC 9e-039| rps3p 3e-031| 40S_S3_KH 4e-028|0.058 RpsC, Ribosomal rps3 3e-007| rpsCribosomal structure and

1.00E-108 rpl10e 2E-044 rpl10e 2e-044| Ribosomal_L16_L10e 4e-028| RplP 2e-026|RplP, Ribosomal 4e-017|L16/L10E ribosomal structure and

Ribosomal_L161E-017 POLXc 0.96 6E-027 Translation,

Ribosomal_L16 protein

1.00E-94 ATP-synt 1E-048 ATP-synt 3E-049 ArfGap 0.51 AtpG, 5E-039 Energy production and conversion

ATP-synt 1e-048| PRK05621 1e-038| AtpG 2e-038| PRK00955 | F0F1-type ATP synthase, gamma subunit

5.00E-39 SMP2 0.65 SMP2 | 0.20 protein function in plasmid mainten

SMP2, UncharacterizedGeneral involved prediction only

4.00E-82 LAP4 0.69 LAP4 | aminopeptidase

LAP4, Aspartyl 0.21 Amino acid transport and metabolism

1.00E-19 SapB 3E-007 SapA 4E-004 SapB 0.009|

SapB 3e-007| SAPA 0.001| SapA 0.001| SapB_24E-009 ACC_central | SapB_1 |

6.00E-34 Hfi 3E-062 AP_endonuc_2 2E-018 Hfi, Hydroxypyruvate isomerase

1E-062 Carbohydrate transport and metabo

Hfi 3e-062| PRK09997 1e-045| PRK09989 2e-043| AP_endonuc_2 8e-018| IolE 2e-014| COG4130 |

1.00E-106 WD40 7E-032 WD40 1e-015| WD40 WD40 FOG: WD40 3E-016

WD40 7e-032| COG2319 3E-005 WD40 4e-005| 5E-0071e-004| eIF2A |repeat General function prediction only

9.00E-19 Mal 0.13 0.11

Mal | MAL | MAAL_C | DUF1635 | HECTc 0.040 Amino acid transport and metabolism

0.29 Mal, Methylaspartate ammonia-lyase

1.00E-89 Mito_carr 1E-012 Mito_carr 3E-013

Mito_carr 1e-012| PRK04452 | CheW | 0.29 Cell motility and secretion

CheW, Chemotaxis signal transduction protein / Signal tr

7.00E-46 RplW 3E-012 Ribosomal_L234E-009 COLFI 0.39 RplW, Ribosomal protein L23 TEBP_beta 0.050| rplW PRK

1E-012 0.014|

RplW 3e-012| rplW 1e-010| Ribosomal_L23 1e-008| PRK09138 0.003| PRK08173 Translation, ribosomal structure| and

2.00E-37 PRK05035 1E-005 MMS22 0.053 TOP2c infB TolA, Membrane protein involved | colicin

0.005 Cell envelope biogenesis,

PRK05035 1e-005| TolA 0.015| tolA | PRK00247 | 0.19 | PRK11778 | PRK12373 | PRK00409indnaK | uptakeouter mem

4.00E-81 eIF2A 6E-017 eIF2A 4e-015| WD40 0.67 1E-015 General function prediction only

eIF2A 6e-017| COG5354 2E-017 Rgp1 | tolB | COG0478 | Uncharacterized protein, contains Trp-Asp (WD) repeat

4.00E-98 rpl2p 4E-059 Ribosomal_L2_C

2E-035 RplB, Ribosomal protein L2

2E-052 Translation,

rpl2p 4e-059| RplB 7e-052| Ribosomal_L2_C 7e-035| rplB 2e-023| rpl2 7e-020| MD-1_MD-2 | ribosomal structure and

5

Mob1_phoceinE-064 Mob1_phocein

Mob1_phocein 5e-064| 1E-064 0.35 conserved in bacteria

Uncharacterized proteinFunction unknown

1.00E-13 MFS_1 3E-004 MFS_1 9E-005 Permeases of 0.016 General function prediction only

the major facilitator

MFS_1 3e-004| COG2270 0.053| DNA_topoisoIV 0.060| AraJ 0.060| FucP | PRK05777 | fliF | superfamily

1.00E-167 MgtA 5E-043 Cation_ATPase_C

8E-037 MgtA, Cation 1E-043 ATPase ion transport and metaboli

transport Inorganic

MgtA 5e-043| Cation_ATPase_C 3e-036| ZntA 2e-009| PRK10517 3e-009| zntA 3e-004| PRK10671 0.001| KdpB 0.006

7.00E-78 Ribosomal_S8e8E-031 Ribosomal_S8e2E-031

Ribosomal_S8e 8e-031| RPS8A 3e-022| PRK04049 5e-016| 9E-023 Translation, ribosomal structure and

RPS8A, Ribosomal protein S8E

7.00E-17 DUF1014 2E-018 DUF1014 7E-019 TOPEUc 0.13 Predicted Zn-dependent peptidases, insulinase-like

0.026

DUF1014 2e-018| PRK11281 0.046| COG1026 0.084| U79_P34 | M16C_assoc | General function prediction only

2.00E-07 COG3662 0.60 COG3662 | WD40 0.19 conserved in bacteria

0.071 Uncharacterized proteinFunction unknown

4.00E-54 NOGCT 8E-013 NOGCT 2E-013 G_alpha 0.25 Predicted GTPase0.001 General function prediction 0.007|

NOGCT 8e-013| NOG 3e-011| Obg_like 6e-004| obgE 6e-004| obgE 0.001| Obg 0.001| COG1084 0.003| Obg only P

PRK07764 8E-004 DUF1682 0.28 TOPEUc 0.34 RPN2, 26S proteasome regulatory infB | modification, protei

PRK12323 0.074| complex component

PRK07764 8e-004| PRK05648 0.003| PRK05035 0.016| PRK07003 0.073|0.33 Posttranslational motB |

1.00E-09 6E-010

Peptidase_M16_C Peptidase_M16_C

2E-010

Peptidase_M16_C 6e-010| PqqL | 0.11 General function prediction only

PqqL, Predicted Zn-dependent peptidases

9.00E-08 DUF1683 2E-025 DUF1683 6E-026 INB

DUF1683 2e-025| 0.51 of methanol dehydrogenase type

0.039 Beta-propeller domains General function prediction only

4.00E-31 RfaG 5E-011 Glycos_transf_1

2E-010

RfaG 5e-011| Glycos_transf_1 6e-010| 2E-011 Cell

RfaG, Glycosyltransferase envelope biogenesis, outer mem

2.00E-64 P5_C 2E-053 P5_C 2e-053|UPF0075 0.57

5.00E-07 BRICHOS 6E-015 BRICHOS 2E-015 G_alpha

BRICHOS 6e-015| 0.37 conserved in bacteria

0.31 Uncharacterized proteinFunction unknown

2.00E-83 3E-070

Ribosomal_L18ae Ribosomal_L18ae

1E-070

Ribosomal_L18ae 3e-070| RPL20A 2e-012| 7E-013 Translation, ribosomal structure and

RPL20A, Ribosomal protein L20A (L18A)

5.00E-47 Hexokinase_2 1E-040 Hexokinase_2 3E-041 IL7

Hexokinase_2 1e-040| COG5026 1e-021| 0.95 Hexokinase 4E-022 Carbohydrate transport and metabo

0.95 in chromosome chromosome partiti

HEC1, Protein involved Cell division andsegregation, interac

5.00E-58

3.00E-77 Ribosomal_L7 Ribosomal_L30 5E-012 POLBc 0.30 RpmD, Ribosomal protein L30/L7E

9E-009 2e-011| RpmD 3e-008| prfC | RF3 |

7E-058 Ribosomal_L7 7e-058| rpl30p 4e-022| Ribosomal_L30 2e-011| Ribosomal_L30_L7Translation, ribosomal structure and

2.00E-10 DUF481 0.78

1.00E-12 TFA2 0.42 TFA2 | I-set 0.43 OSTEO 0.13 Transcription

0.56 TFA2, Transcription initiation factor IIE, beta subunit

1.00E-57 4E-038 tRNA_bind_EMAP-II_like 6E-022 metG 3e-024| tRNA_bindingDomain 4e-023| tRNA_bind 2e-021| tRNA_bind_EcMetR

tRNA_bind_EMAP- tRNA_bind 4e-038| domain

ARC1, EMAP2E-014 General function prediction only

4.00E-54 DUF1649 2E-036 PRK06111 0.17 Lipid metabolism

DUF1649 5E-036 DUF1649 5e-036| DUF1501 0.099| LIF_OSM | 0.43 Acetyl/propionyl-CoA carboxylase, alpha subunit

2.00E-71 RpsC Ribosomal_S3_C1E-020 AP2Ec 0.70 RpsC, Ribosomal protein S3

|

1E-025 RpsC 1e-025| rps3p 2e-021| Ribosomal_S3_C 4e-020| rpsC 0.018| rps3 4E-026 Translation, ribosomal structure and

5.00E-67 4E-070 Ribosomal_S7e 4e-070| COG4320 PSN

Ribosomal_S7e Ribosomal_S7e 0.27 0.14 conserved in bacteria

1E-070 | PRK06418 | PbpC | Uncharacterized proteinFunction unknown

1.00E-36 Isochorismatase

1E-008 SEC14 0.41 PncA, Amidases related 0.001| nicotinamidase biosynthesis

3E-004 to nicotinamidase

YcaC_related5E-039 YcaC_related 5e-039| cysteine_hydrolases 2e-015| Isochorismatase 4e-008| PncASecondary metabolites 0.003| PRK1

1.00E-62 7E-038 Mt_ATP-synt_B 7e-038| 2E-038 RasGEF

Mt_ATP-synt_B Mt_ATP-synt_B 0.40 Transcription

0.25 RPO41, Mitochondrial DNA-directed RNA polymerase

1.00E-20 DUF1097 DUF1097 0.027 LYZ1 0.54 0.22 Amino acid transport and metabolism

0.090 DUF1097 0.090| CRISPR_Cse1 | PRK10747 | COG1685 | Archaeal shikimate kinase

6E-020

1.00E-36 Clathrin_lg_ch Clathrin_lg_ch

2E-020 TOPEUc 0.059 Uup, ATPase components of ABC transporters withonly

0.017 General function prediction duplicat

Clathrin_lg_ch 6e-020| Uup 0.054| PRK05771 0.057| BMS1 | Peptidase_C37 | Atrophin-1 | PRK00409 | PRK05218 |

2.00E-03 SrfB 0.54 SrfB | TR_FER 0.17 Function unknown

0.10 SrfB, Uncharacterized protein conserved in bacteria, putativ

1E-075

3.00E-78 cyclophilin_ABH Pro_isomerase2E-068 HALZ 0.40 PpiB, 7e-043|9E-041cis-trans isomerase modification, protei

PpiB Posttranslational (rotamase) - cyclo

cyclophilin_ABH_like 1e-075| Pro_isomerase 7e-068| cyclophilin Peptidyl-prolyl3e-040| cyclophilin_WD40 2e-035|cyclop

COG3264 0.023 V_ATPase_I 0.44

COG3264 0.023| COG4372 | COG2433 | PRK08993 | PRK02224 | 0.007 Cell envelope channel

Small-conductance mechanosensitivebiogenesis, outer mem

7E-055

1.00E-62 Ribosomal_S19e Ribosomal_S19eRPS19A 3e-037| PRK09333 RPS19A, Ribosomal protein HTH_DTXR

9E-038 Translation, ribosomal

Ribosomal_S19e 7e-055|2E-055 HTH_DTXR 0.0101e-033| PRK09209 | COG1693 |S19E (S16A) | structure and

4.00E-79 EF1G 3E-040 EF1G 3e-040|EF1G 8E-041

8.00E-63 AtpE 0.009 PRK08344 0.014 G_alpha 0.48 AtpE, F0F1-type | PRK06558 | EscV | ATP-synt_C | FHIPEP

0.003 Energy subunit c/Archaeal/vacuola

AtpE 0.009|Ail_Lom 0.043| Ail_Lom 0.047| PRK06271 0.065| PRK06251 ATP synthase,production and conversion

2.00E-63 UDPGP 2E-039 UDPGP 7E-040

UDPGP 2e-039| COG4284 7e-016|ZU5 pyrophosphorylase

0.30 UDP-glucose 2E-016 Carbohydrate transport and metabo



3.00E-61 Ribosomal_S3Ae2E-041 Ribosomal_S3Ae RPS1A RL11 0.45 RPS1A, Ribosomal protein S3AE ribosomal structure and

Ribosomal_S3Ae 2e-041|7E-042 1e-025| PRK04057 2e-015| PRK08267 | 4E-026 Translation,

6.00E-11 8

Abhydrolase_3E-005 Abhydrolase_3E-005

3

Abhydrolase_3 8e-005| Aes 0.001| DAP2 | DLH | 3E-004

Aes, Esterase/lipase Lipid metabolism

2.00E-39 Ribosomal_L36e4E-018 Ribosomal_L36eRPL36A Zn_pept

Ribosomal_L36e 4e-018| 1E-018 3e-009| 9E-010 Translation,

0.077 RPL36A, Ribosomal protein L36E ribosomal structure and

2.00E-16 PRK07334 6E-028 ACT 0.028 IlvA Threonine dehydratase acid transport and metabolism

2E-016 Amino

PRK07334 6e-028| PRK08198 3e-024| PRK08526 3e-019|IlvA, 6e-016| PRK06382 2e-013| ACT_ThrD-II-like 9e-009| P

Tim17 0.17 Tim17

Tim17 | PRK09841 | 0.050

DUF629 0.24 DUF629 0.071

DUF629 | EF-G | Myco_haema | IFabd 0.60

1.00E-05 2E-010

Sulfotransfer_2 Sulfotransfer_2

5E-011 CorA, 0.11 Inorganic ion

Sulfotransfer_2 2e-010| CorA | COG3893 | PRK07847 | entE | Mg2+ and Co2+ transporters transport and metaboli

5.00E-69 Rab7 2E-059 Ras 5E-034 RAB 1E-039 2e-033| Rab11_like 4e-025| Ras_like_GTPase 7e-025|

3E-015 General G proteins

Rab7 2e-059| RAB 8e-038| Rab 2e-034| Rab9 2e-034| RasGTPase SAR1 and related smallfunction prediction only Ra

1.00E-79 PRK09569 8E-056 Citrate_synt 3E-043 INB 0.49 GltA, Citrate synthase Energy production and conversion

2E-030

PRK09569 8e-056| Citrate_synt 1e-042| GltA 6e-030| gltA 1e-008| PRK12351 6e-008| PRK12349 0.022| PRK12350 0.

8.00E-37 DER1 3E-023 DER1 3e-008|

DER1 3e-023| COG5291 9E-024 8E-009 Function unknown

Predicted membrane protein

9.00E-55 4E-029

Ribosomal_L19e_ Ribosomal_L19e9E-022 UAS 0.25 RPL19A, Ribosomal RPL19A 8e-015| rpl19e structure and

3E-015 Translation,

Ribosomal_L19e_E 4e-029| Ribosomal_L19e 7e-022| Ribosomal_L19e 3e-021|protein L19E ribosomal2e-012| Ribos

2.00E-53 FAA1 2E-012 H15 0.71 5E-013 Lipid metabolism

FAA1 2e-012| PRK08180 0.001| PRK12582 | PRK00950 | FAA1, Long-chain acyl-CoA synthetases (AMP-forming)

2.00E-63 rpl3p 5E-013 rpl3p 5e-013| Ribosomal_L3 2e-004| RplC 0.031| NOZZLE RplC, Ribosomal protein L3

Ribosomal_L3 7E-005 MUTSd 0.44 | 0.010 Translation, ribosomal structure and

RPA1_DBD_C0.100 Ebola_NP 0.10

RPA1_DBD_C 0.100| Ebola_NP | CPDc 0.23

1.00E-66 Rab11_like 3E-047 3e-047| RAB 3E-031 Ras 1e-030| Rab 1e-027|GTPase SAR1 Rab4 4e-025| Rab1_Ypt1prediction only

Rab11_like Ras 1e-036| RAB 1E-008 General G proteins

2E-038 Rab2 5e-026| and related smallfunction 1e-024| Rab8_Rab

WT1 0.93 0.97 Signal transduction mechanisms

KdpD, Osmosensitive K+ channel histidine kinase

9.00E-65 rps4p 4E-019 S4 4E-007 S4 9E-006 RpsD, 4e-006| Ribosomal_S4 5e-005| rps4 1e-004|

3E-016 Translation, ribosomal structure and

rps4p 4e-019| RpsD 1e-015| rpsD 2e-007| S4 1e-006| PRK12565 Ribosomal protein S4 and related proteins S4 2e-0

8.00E-10 0.92 predicted to be recombination, rep

Uncharacterized proteinDNA replication, involved in DNAand

3.00E-63 PRX_Typ2cys 1E-054 AhpC-TSA 7E-016 35EXOc 1.00 AhpC, Peroxiredoxin Posttranslational modification, protei

2E-048

PRX_Typ2cys 1e-054| AhpC 7e-048| PRX_1cys 2e-026| PRX_family 5e-021| PRK10382 3e-019| AhpC-TSA 2e-015| P

6.00E-63 PRK04293 0.69 PRK04293 | PRK08332 | PRK10420 | 0.41 conserved in bacteria

Uncharacterized proteinFunction unknown

1.00E-42 Annexin 4E-015 Annexin 1E-015 ANX

Annexin 4e-015| ANX 4e-011| 6E-013

9.00E-36 1E-018

Ribosomal_S30 Ribosomal_S30 5E-019 UBQ 3e-004| Ribosomal protein S30 Translation, ribosomal ubiquitin |

6E-004

Ribosomal_S30 1e-018| Fubi 3e-013| PRK093365E-005 COG4919 0.002| UBQ 0.003| RAD23_N | UBL |structure and

2.00E-56 HSP70 9E-019 HSP70 3E-019 9e-012| 8e-008| hscA Molecular chaperone

HSP70 9e-019| dnaK 3e-016| DnaKRIBOc dnaK 0.31 DnaK,0.025| 3E-012 Posttranslational modification, protei

4.00E-45 RNA_pol_Rpb61E-011 RNA_pol_Rpb6 3E-012 OSTEO 0.46 RpoZ, rpoK 4e-008| COG5406 | COG3181 | ycf2 |

7E-009 Transcription

RNA_pol_Rpb6 1e-011| rpoK 3e-011| RpoZ 2e-008| rpoK 3e-008|DNA-directed RNA polymerase, subunit K/omega

3.00E-58 Ubiquitin 6E-023 Ribosomal_S27 2E-018 UBQ 2E-015 UBQ 1e-013|1E-008 7e-013| UBL ribosomal structure and

Nedd8 Translation,

Ubiquitin 6e-023| Ribosomal_S27 6e-018| ubiquitin 3e-014|RPS31, Ribosomal protein S27AE 2e-011| AN1_N 9e-010|

7.00E-17 HX 7E-015 HX 2e-007| 2E-007 5e-007| PRK09039 |

HX 7e-015| Hemopexin HemopexinHX 3E-009

PRK06464 0.59 PRK06464 |MED7 0.36 0.64 Posttranslational

Cullin, a subunit of E3 ubiquitin ligase modification, protei

4.00E-29 PRK08188 0.11 TPR |

PRK08188 |TPR_2 TPR_2 |0.11 TPR 0.15

1.00E-30 7E-033

Peptidase_C1A Peptidase_C15E-031 Pept_C1 8E-024 Cysteine protease8E-006 Posttranslational modification, protei

Peptidase_C1A 7e-033| Peptidase_C1 2e-030| Pept_C1 5e-022| Peptidase_C1A_CathepsinB 6e-015| Peptidase_C1A

hATC 0.18 hATC

hATC | Peptidase_C19E | 0.057 polysaccharide export protein

KpsC, Capsule0.34 Cell envelope biogenesis, outer mem

4.00E-21 DUF689 1E-036 DUF689 5E-037

DUF689 1e-036| COG5636 3e-017| 1E-017 Function unknown

Uncharacterized conserved protein, contains Zn-ribbon-like

PRK12566 0.28 PRK01497

PRK12566 |Gasdermin | 0.77

Peptidase_S390.26 Peptidase_S39 0.083

Peptidase_S39 | PRK08257 | PRK12678 |

1.00E-20 VP7 0.43 VP7

VP7 | B-block_TFIIIC | 0.14

8.00E-35 2E-023

Adap_comp_sub Adap_comp_sub 2e-023| 7E-024 ACTIN

Adap_comp_sub | MRS6 |

gltA 0.20 sorting-associated protein

0.40 MRS6, Vacuolar proteinIntracellular trafficking and secretion

COG4920 0.26 COG4920 | EXOIII | EXOIII 0.086 Function unknown

0.009 Predicted membrane protein

8.00E-33 PRK09243 8E-012 Prominin 0.31

PRK09243 8e-012| PRK12484 5e-005| PRK08662 0.073| PRK05297 | Prominin |

2.00E-58 PRK09280 2E-055 ATP-synt_ab_C 3e-051| AtpD, F0F1-type ATP synthase, PRK04192 conversion

1E-051 Energy production and

PRK09280 2e-055| AtpD 1E-021 atpB 2e-044| PRK12597 1e-037| ATP-synt_ab_C 4e-021| beta subunit0.003| NtpA 0.0

9.00E-42 HUL4 2E-034 HECT 3E-034 HECTc 1E-029 HUL4, Ubiquitin-proteinPosttranslational modification, protei

HUL4 2e-034| HECT 8e-034| HECTc 9e-030| HECTc 8e-028| 5E-035 ligase

3.00E-42 6PGL 4E-047 Glucosamine_iso 0.51 AAA 4e-011| NagB, 6-phosphogluconolactonase/Glucosamine-6-phospha

3E-031 Carbohydrate transport and metabo

6PGL 4e-047| NagB 1e-030| GlcN6P_deaminase 0.085 nagB 2e-007| PRK12358 4e-007| PRK02122 0.011| PRK097

4.00E-36 DUF1290 0.81 0.38 Signal transduction transduction

Bacteriophytochrome (light-regulated signalmechanisms his

2E-027 GST_C_Delta_Epsilon 2e-027| GST_C_Ure2p_like 9e-008| GST_C_1 2e-006| GST_C_Theta 5e-006| GST_C_Beta 7e

GST_C_Delta_Eps GST_C 3E-006 HECTc 4E-005 Posttranslational modification, protei

0.26 Gst, Glutathione S-transferase

Herpes_LMP2 0.45 RPOL4c 0.52 Predicted membrane PRK09111unknown | PRK03427 |

0.20 Function | COG5373

PRK12323 0.001 PRK12323 0.001| PRK08853 0.060| PRK07764 0.083| PRK05648 | PRK10218 | protein

MCPVI 0.51 alkPPc 0.48

GatA Amidase 9e-014| HYDRO 0.014 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subu

8E-015 Translation, ribosomal structure and

3E-014 GatA 3e-014| PRK06170 8E-012 gatA 3e-012| Amidase 3e-011| PRK08310 8e-011| PRK07488 1e-007| PRK06169 2e

4.00E-14 DUF92 DUF92 0.017

0.058 DUF92 0.058| COG1836 0.078| COG0182 | 0.022 Function unknown

Predicted membrane protein

8.00E-46 TFIID_20kDa1E-022 TAF61, Transcription Transcription

TFIID_20kDa3E-022 TFIID_20kDa 3e-022| TAF61 1e-021| L-fuc_L-ara-isomerases | HHT1 | 4E-022 initiation factor TFIID, subunit TAF12 (

3.00E-47 PRK11459 Ndh |

0.29 PRK11459 |PUCC PRK07860 | 0.76 0.11 Energy production and conversion

Ndh, NADH dehydrogenase, FAD-containing subunit

2.00E-21 2E-030 proteasome_beta_type_62E-012 proteasome_beta 8e-018| Proteasome 8e-012| proteasome_protease_HslV 1e-011|

proteasome_beta Proteasome 2e-030| G_alpha 6E-012 Posttranslational modification, protei

0.40 PRE1, 20S proteasome, alpha and beta subunits

5.00E-22 2e-006| GimC 0.007| GimC, Prefoldin,

0.002 Posttranslational

Prefoldin_2 2E-006 Prefoldin_2 Prefoldin_2 5E-007 PRK10642 0.014| lldD 0.055| PRK09343 | chaperonin cofactor modification, protei

1.00E-40 1E-025 Ribosomal_L31e 1e-025| 3E-026 2e-014| PRK01192 2e-010| RIO1_euk |

Ribosomal_L31e RPL31A Tryp_SPc

Ribosomal_L31e 5E-015 Translation,

0.50 RPL31A, Ribosomal protein L31E ribosomal structure and

2.00E-41 Peptidase_M20

1E-004 HTTM 5e-006| Peptidase_M20 5e-004| ArgE acid transport and metabolism

0.001 Amino 0.004| PAD_porph 0.042| PR

PRK08201 3E-008 PRK08201 3e-008| PRK09104 1e-007| PRK079070.60 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate

7.00E-03 lplA 0.002 lplA 0.002|

1.00E-37 rpl15p L15 2E-005 IL2 0.007 RplO, 0.003| RPL18A 0.024|

1E-006 Translation, ribosomal

1E-008 rpl15p 1e-008| RplO 5e-006| L15 8e-005| PRK04005 0.002| rplO Ribosomal protein L15 IL2 | PRK06276 | structure and

COG3333 0.29 COG3333 | 0.079 conserved in bacteria

Uncharacterized proteinFunction unknown

9.00E-52 Tctex-1 Tctex-1

2E-036 Tctex-1 2e-036| 5E-037

2.00E-40 5E-025 Ribosomal_L35Ae 5e-025| COG2451 1e-019| PRK04337 2e-010|

Ribosomal_L35Ae 2E-025

Ribosomal_L35Ae 3E-020 Translation, ribosomal structure and

Ribosomal protein L35AE/L33A

5.00E-34 0.69 Energy production selenocysteine-c

BisC, Anaerobic dehydrogenases, typicallyand conversion

0 Retrotrans_gag .004 HLH

0 Myc_N MAK16, Nuclear proteinGeneralPRK04537 | DUF566

0.090| with | function prediction only

Retrotrans_gag .015 Retrotrans_gag 0.015| MAK16 0.018| AF-4 0.038| 0.11 0.077| DUF7550.005 SelP_NHMG-like acidic region | PcoB

2.00E-50 rps9p Ribosomal_S9 E-023

5 RpsI, Ribosomal protein S9

5E-021 Translation, ribosomal structure

4E-025 rps9p 4e-025| Ribosomal_S9 2e-022| RpsI 2e-020| rpsI 3e-010| rps9 3e-006| Alpha_L_fucos 0.082| PRK05787 | and

5.00E-44 rpl6p Ribosomal_L61E-009 CPDc 1E-010 Translation,

5E-014 rpl6p 5e-014| RplF 5e-010| Ribosomal_L6 4e-009| 0.60 RplF, Ribosomal protein L6P/L9E ribosomal structure and

4.00E-10

1.00E-13 Glyco_32 0.15

2.00E-05 Attacin_C Attacin_C

7E-004 Attacin_C 7e-004| 2E-004 BID_1 0.49

SKN1 0.75

ModC 0.32 ModC | 0.078 Inorganic ion system, and metaboli

ModC, ABC-type molybdate transporttransport ATPase com

Best

match to Length of First First Number

PRK Extent of best % Match residue of residue of of

database E value Match Score match match % identity length match sequence segments

0.006 gnl|CDD|82074 tau.

DNA polymerase III subunits gamma and 35.9 263 825 14 32 359 1 4

1E-116 gnl|CDD|81248 411

proteasome-activating nucleotidase. 323 396 55 82 70 1 1

8E-26 gnl|CDD|84069 111

glycogen branching enzyme. 333 633 27 53 251 1 1

6E-25

magnesium transporter.gnl|CDD|83278 108 188 884 30 21 565 3 1

2E-18 gnl|CDD|81688

succinyl-CoA synthetase subunit alpha. 87.1 148 290 34 51 146 1 1



1E-163 gnl|CDD|82909

F0F1 ATP synthase subunit beta. 568 304 466 79 65 40 3 1

malic enzyme.1E-23 gnl|CDD|82162 104 213 756 35 28 161 99 1



0.37 gnl|CDD|75845 29.6

short chain dehydrogenase. 91 281 26 32 27 41 1

0

oxidoreductase. .46 gnl|CDD|76363 29.3 31 294 45 11 237 11 1

1E-102 gnl|CDD|75792 366

acetyl-CoA acetyltransferase. 300 392 57 77 92 1 1

0.019 gnl|CDD|82694

N-acetylmuramoyl-L-alanine amidase. 33.9 47 619 34 8 23 152 8

1E-102 gnl|CDD|80608 364

molecular chaperone DnaK. 300 635 54 47 317 1 1

5E-58

elongation factor EF-2. gnl|CDD|82272 218 301 725 36 42 270 1 1

0.88 gnl|CDD|82692 28.3

preprotein translocase subunit SecF. 93 291 17 32 40 156 1

1E-136

elongation factor Tu. gnl|CDD|80474 479 288 394 67 73 3 24 1

3E-40 gnl|CDD|78909 159

histidyl-tRNA synthetase. 233 425 38 55 3 35 1

1E-65 gnl|CDD|80642 243

glycine cleavage system aminomethyltransferase T. 292 364 35 80 59 1 1

0.59 accessory protein FdhE.

formate dehydrogenasegnl|CDD|81160 28.8 77 307 25 25 76 22 1





2E-07 gnl|CDD|77683

ATP-dependent. 50.4 141 1293 24 11 1062 33 1

9E-68 gnl|CDD|82573

3-hydroxybutyryl-CoA dehydrogenase. 250 270 503 38 54 22 1 2



2E-76 gnl|CDD|81248 279

proteasome-activating nucleotidase. 244 396 50 62 18 24 1

2E-13 gnl|CDD|82954 70.1 74

phosphoribosylaminoimidazole-succinocarboxamide synthase. 242 28 31 146 1 1

0.038 KefA.

potassium efflux proteingnl|CDD|83816 32.9 107 1100 21 10 186 27 1





transketolase.0.0004 gnl|CDD|81790 39.4 157 665 24 24 96 7 1

0.002 gnl|CDD|82074 tau.

DNA polymerase III subunits gamma and 37.1 259 825 11 31 359 1 2





protein gnl|CDD|81261 173

30S ribosomal1E-44 S2. 176 205 41 86 35 2 1

0.036 gnl|CDD|80900 32.9

3-deoxy-D-manno-octulosonic-acid kinase. 57 240 26 24 131 70 1

0.056 gnl|CDD|82639 32.2

DNA polymerase I. 68 897 29 8 8 31 1

0.007 gnl|CDD|73924

chromosome segregation protein. 35 77 895 16 9 640 12 1

ApaG. 3E-30 gnl|CDD|81606 125 119 124 41 96 2 86 1



3E-68 gnl|CDD|82759

3-ketoacyl-CoA thiolase. 252 234 434 48 54 200 1 1



0.21

hypothetical protein. gnl|CDD|81289 30.2 115 315 21 37 200 1 1

5E-82

malate dehydrogenase.gnl|CDD|81435 297 234 312 58 75 80 1 1

galactokinase.7E-63 gnl|CDD|81522 234 233 387 44 60 157 1 1

protein gnl|CDD|82684

50S ribosomal6E-19 L18P. 88.4 179 192 31 93 55 1 1

7E-10 gnl|CDD|74508

V-type ATP synthase subunit E. 58.1 199 198 30 101 11 19 1

0.000002 gnl|CDD|74512

ribosomal biogenesis protein. 46.6 110 207 30 53 2 19 1

0.002 gnl|CDD|80667

elongation factor 1-beta. 36.7 88 88 21 100 2 139 1

0.22 gnl|CDD|75701

short chain dehydrogenase. 29.7 82 288 29 28 124 31 1

protein gnl|CDD|81274

30S ribosomal1E-61 S5P. 230 206 213 49 97 3 7 1



protein gnl|CDD|81317 130

30S ribosomal1E-31 S3P. 184 193 36 95 14 4 1

protein gnl|CDD|81322 174

50S ribosomal7E-45 L10e. 170 173 45 98 1 1 1

5E-39 gnl|CDD|81665 154

F0F1 ATP synthase subunit gamma. 229 290 30 79 71 6 1

0.65 gnl|CDD|78512 28.2

multidrug resistance outer membrane protein MdtQ. 44 478 36 9 287 49 1

0.63 gnl|CDD|81042 28.2

putative aminopeptidase 2. 24 428 37 6 31 21 1



4E-46 gnl|CDD|77533

hydroxypyruvate isomerase. 178 206 258 42 80 54 6 1





0.24 gnl|CDD|81380 29.5 60

acetyl-CoA decarbonylase/synthase complex subunit delta. 362 21 17 47 152 1

protein gnl|CDD|81720 61.7

50S ribosomal5E-11 L23. 88 91 37 97 2 123 1

0.000004 gnl|CDD|81425

electron transport complex protein RnfC. 45.6 166 640 21 26 438 35 5

0.23 gnl|CDD|81452 29.8

translocation protein TolB precursor. 91 439 26 21 346 10 1

protein gnl|CDD|83109 222

50S ribosomal2E-59 L2P. 173 237 57 73 65 14 1

1 gnl|CDD|83486 27.6

maltodextrin glucosidase. 70 596 25 12 228 129 1

0.32 gnl|CDD|81741 28.9

NADH dehydrogenase subunit N. 108 479 17 23 15 9 1

1E-09

magnesium transporter.gnl|CDD|83278 57.6 121 884 30 14 633 1 1

protein gnl|CDD|81276 79.5

30S ribosomal2E-16 S8e. 92 127 41 72 11 1 1

0.019 KefA.

potassium efflux proteingnl|CDD|83816 32.9 158 1100 21 14 41 4 1

0.71 gnl|CDD|82592

phenol 2-monooxygenase. 28 47 635 40 7 158 99 1

GTPase ObgE. 0.0002 gnl|CDD|84062 40.4 74 336 33 22 266 5 1

0.0003 gnl|CDD|82344 tau.

DNA polymerase III subunits gamma and 38.8 145 730 21 20 371 3 5









0.42 gnl|CDD|81262 28.3

DNA polymerase II large subunit. 73 1123 21 7 232 98 1

0.66 gnl|CDD|73794 27.6

50S ribosomal protein LX. 58 75 24 77 3 75 1

0.63 gnl|CDD|78448 27.8 58

5-methylcytosine-specific restriction enzyme subunit McrB. 459 12 13 208 95 1

0.66 gnl|CDD|80956

Holliday junction-specific endonuclease. 27.5 39 199 35 20 77 18 1



protein gnl|CDD|81823

50S ribosomal2E-22 L30P. 99.4 158 153 27 103 4 15 1





1E-24 gnl|CDD|80537 106

methionyl-tRNA synthetase. 102 668 37 15 568 8 1

0.12 biotin carboxylase subunit.

acetyl-CoA carboxylasegnl|CDD|81849 29.9 46 450 34 10 244 19 1

protein gnl|CDD|81317 96.8

30S ribosomal1E-21 S3P. 129 193 36 67 67 3 1

0.36 factor NusA-like 28.3

transcription elongation gnl|CDD|81944 protein. 61 167 22 37 106 99 1

0.002

hypothetical protein. gnl|CDD|83841 35.8 89 188 24 47 100 55 1

0.43

heat shock protein 70. gnl|CDD|79309 28 47 622 36 8 550 40 1

0.1 synthesis protein. 30

predicted protoheme IXgnl|CDD|83454 51 398 31 13 14 24 1

0.025 gnl|CDD|81737

V-type ATP synthase subunit I. 32.2 63 639 28 10 188 22 1



cis-trans isomerase A (rotamase

peptidyl-prolyl 2E-11 gnl|CDD|83581 62.4 A). 132 190 35 69 38 23 1

0.12 gnl|CDD|82767

2-deoxy-D-gluconate 3-dehydrogenase. 29.9 81 253 29 32 24 72 1

protein gnl|CDD|82938 137

30S ribosomal5E-34 S19e. 150 150 38 100 2 4 1

0.45 gnl|CDD|75172

3-hydroxybutyryl-CoA dehydratase. 28 28 260 35 11 228 9 1

0.019 gnl|CDD|76598 32.7

V-type ATP synthase subunit K. 145 159 25 91 6 1 2





protein gnl|CDD|81279

30S ribosomal7E-16 S3Ae. 77.2 108 210 37 51 93 1 1





2E-28

threonine dehydratase. gnl|CDD|82201 118 133 401 45 33 260 4 1

0.12 gnl|CDD|77439 29.7

cryptic autophosphorylating protein tyrosine kinase Etk. 38 726 31 5 427 89 1

0.52

DNA translocase FtsK. gnl|CDD|77693 27.5 78 1342 30 6 422 73 1

0.4 gnl|CDD|82390 28.7

amidophosphoribosyltransferase. 66 487 28 14 168 3 1

0.001 gnl|CDD|80503 36.5

GTP-binding protein Era. 87 295 28 29 105 43 1

3E-56

type I citrate synthase. gnl|CDD|77261 210 140 437 59 32 290 3 1



protein gnl|CDD|82685

50S ribosomal7E-13 L19e. 67.1 90 149 43 60 59 1 1

0.0004

feruloyl-CoA synthase. gnl|CDD|82515 37.9 103 619 23 17 507 46 1

protein gnl|CDD|81334

50S ribosomal2E-13 L3P. 68.7 103 336 29 31 256 1 1









protein gnl|CDD|81277

30S ribosomal2E-19 S4. 88.8 109 177 39 62 55 3 1



C22 subunit. 1E-19 gnl|CDD|83222 89.3 124 187 34 66 60 1 1

0.3 gnl|CDD|81347 28.3

adenylosuccinate synthetase. 78 333 19 23 96 33 1

0.74 gnl|CDD|81279 26.7

30S ribosomal protein S3Ae. 40 210 32 19 12 4 1

0.0001 gnl|CDD|82941 39.3

30S ribosomal protein S30e. 46 50 45 92 4 75 1

1E-16 gnl|CDD|80608

molecular chaperone DnaK. 79 119 635 32 19 502 9 1

1E-11 gnl|CDD|80822

DNA-directed RNA polymerase subunit K.62.7 70 106 42 66 31 60 1

0.000005 gnl|CDD|80666 44.1

30S ribosomal protein S27ae. 49 50 48 98 1 73 1

0.24

hypothetical protein. gnl|CDD|82781 28.3 59 343 37 17 257 41 1

0.26 gnl|CDD|81952 28.2

phosphoenolpyruvate synthase. 19 794 73 2 401 80 1

0.051 gnl|CDD|82522 30.7

ribonucleotide-diphosphate reductase subunit alpha. 35 714 45 5 66 39 1

0.016

hypothetical protein. gnl|CDD|75797 32.2 41 507 31 8 213 86 1





0.12

glycine dehydrogenase.gnl|CDD|79042 29.2 34 957 35 4 853 39 1

0.38 gnl|CDD|82563

acetyl-CoA acetyltransferase. 27.5 30 500 33 6 111 75 1



0.24

type II citrate synthase. gnl|CDD|81661 27.8 91 415 27 22 23 14 1



4E-12 gnl|CDD|82879

nicotinate phosphoribosyltransferase. 64 104 474 30 22 366 1 1

8E-56 gnl|CDD|82909

F0F1 ATP synthase subunit beta. 208 113 466 78 24 354 1 1



8E-08 gnl|CDD|80671

glucosamine-6-phosphate deaminase. 51 187 266 21 70 72 2 1

0.0004 gnl|CDD|78817 tau.

DNA polymerase III subunits gamma and 38.5 165 681 21 24 367 32 1

large subunit. 0.25 gnl|CDD|77628 27.7 86 597 29 14 26 17 1

amidase. 3E-14 gnl|CDD|81868 70.7 112 490 33 23 377 8 1



0.88 gnl|CDD|83584 25.7 35 222

predicted transporter subunit: ATP-binding component of ABC superfamily. 34 16 163 16 1

0.11 gnl|CDD|78512 29

multidrug resistance outer membrane protein MdtQ. 31 478 35 6 166 35 1

0.033 gnl|CDD|81250 30.5

proteasome subunit alpha. 78 247 17 32 145 1 1

betaine gnl|CDD|83374 33.4

proline/glycine0.005 transporter. 55 499 27 11 438 35 1

protein gnl|CDD|80835 59.5

50S ribosomal7E-11 L31e. 68 88 41 77 9 2 1

1E-08

hypothetical protein. gnl|CDD|76477 52 93 455 27 20 363 13 1

ligase

lipoate-protein0.0006 A.gnl|CDD|81213 36.2 98 338 27 29 226 4 1

protein gnl|CDD|81945 53.3

50S ribosomal5E-09 L15P. 103 148 33 70 45 2 1

0.81 gnl|CDD|82915 25.8

6-phosphogluconate dehydrogenase. 22 460 45 5 403 58 1



protein gnl|CDD|81364

50S ribosomal7E-11 L35Ae. 59.5 97 87 29 111 5 1 1



0.08 gnl|CDD|74701

ATP-dependent RNA helicase RhlB. 32 101 572 24 18 433 171 1

protein gnl|CDD|80683

30S ribosomal1E-25 S9P. 108 103 133 51 77 39 1 1

protein gnl|CDD|81628

50S ribosomal2E-14 L6P. 71.4 95 181 37 52 87 1 1

0.43

hypothetical protein. gnl|CDD|83935 26.9 88 163 22 54 85 2 1

Orientatio Best

n of match to Length of First First

assemble CP-PEP Extent of best % Match residue of residue of

d output database E value Match Score match match % identity length match sequence

FOR 3.00E-98

CPIJ011200-PA CPIJ011200-PA 354 339 2531 59 13 0 0

FOR 0.00E+00

CPIJ003334-PA CPIJ003334-PA 632 323 393 98 82 68 1

FOR 0.00E+00

CPIJ006166-PA CPIJ006166-PA 663 323 689 95 47 289 1

FOR 1.00E-180

CPIJ018021-PA CPIJ018021-PA 626 317 995 97 32 626 1

FOR 0.00E+00

CPIJ000859-PA CPIJ000859-PA 636 316 1096 98 29 651 1

1.00E-170

CPIJ003641-PA CPIJ003641-PA 595 314 557 92 56 108 1

FOR 1.00E-165

CPIJ006209-PA CPIJ006209-PA 578 313 511 95 61 67 1

FOR 1.00E-175

CPIJ012341-PA CPIJ012341-PA 611 306 653 97 47 258 1

1.00E-158

CPIJ000349-PA CPIJ000349-PA 553 305 521 88 59 1 1

FOR 1.00E-174

CPIJ009808-PA CPIJ009808-PA 605 302 376 99 80 56 1

FOR 1.00E-173

CPIJ011522-PA CPIJ011522-PA 604 302 594 97 51 239 1

FOR 1.00E-165

CPIJ002342-PA CPIJ002342-PA 575 302 398 96 76 97 1

FOR 1.00E-148

CPIJ001357-PA CPIJ001357-PA 520 301 2098 83 14 356 1

FOR 1.00E-169

CPIJ003550-PA CPIJ003550-PA 588 300 657 99 46 345 1

FOR 1.00E-175

CPIJ001132-PA CPIJ001132-PA 608 299 1031 98 29 545 1

FOR 1.00E-166

CPIJ007204-PA CPIJ007204-PA 580 298 3324 96 9 2863 1

FOR 1.00E-169

CPIJ009962-PA CPIJ009962-PA 590 295 462 100 64 38 16

FOR 1.00E-163

CPIJ016525-PA CPIJ016525-PA 569 295 521 96 57 29 1

FOR 1.00E-158

CPIJ014981-PA CPIJ014981-PA 552 291 413 94 70 93 1

FOR 1.00E-158

CPIJ015616-PA CPIJ015616-PA 551 281 305 97 92 1 1

1.00E-150

CPIJ011929-PA CPIJ011929-PA 528 279 439 95 64 1 1

1.00E-141

CPIJ001052-PA CPIJ001052-PA 498 279 900 86 31 516 1

FOR 1.00E-145

CPIJ005595-PA CPIJ005595-PA 508 273 2419 94 11 2129 1

FOR 1.00E-149

CPIJ006479-PA CPIJ006479-PA 524 270 305 97 89 36 1

1.00E-120

CPIJ017724-PA CPIJ017724-PA 427 268 564 83 48 230 1

FOR 1.00E-148

CPIJ009931-PA CPIJ009931-PA 519 267 402 99 66 1 1

FOR 1.00E-148

CPIJ009002-PA CPIJ009002-PA 520 267 429 96 62 163 1

FOR 1.00E-149

CPIJ011733-PA CPIJ011733-PA 521 267 1332 95 20 74 1

1.00E-148

CPIJ006869-PA CPIJ006869-PA 520 266 288 90 92 23 1

1.00E-121

CPIJ017599-PA CPIJ017599-PA 431 265 344 81 77 81 1

FOR 1.00E-147

CPIJ011779-PA CPIJ011779-PA 518 264 438 94 60 175 1

FOR 2.00E-89

CPIJ011200-PA CPIJ011200-PA 325 260 2531 65 10 0 0

1.00E-145

CPIJ014120-PA CPIJ014120-PA 509 258 556 96 46 299 1

1.00E-145

CPIJ014120-PA CPIJ014120-PA 509 258 556 96 46 299 1

FOR 1.00E-136

CPIJ013899-PA CPIJ013899-PA 479 258 282 93 91 36 1

FOR 9.00E-64

CPIJ018269-PA CPIJ018269-PA 239 253 749 46 34 469 2

FOR 1.00E-137

CPIJ018234-PA CPIJ018234-PA 483 249 291 97 86 42 1

FOR 1.00E-111

CPIJ004013-PA CPIJ004013-PA 397 249 1194 87 21 552 3

FOR 1.00E-136

CPIJ013390-PA CPIJ013390-PA 478 245 381 93 64 137 1

1.00E-121

CPIJ005306-PA CPIJ005306-PA 429 245 410 90 60 88 1

FOR 1.00E-136

CPIJ018065-PA CPIJ018065-PA 479 239 467 99 51 229 1

1.00E-116

CPIJ005493-PA CPIJ005493-PA 414 237 252 90 94 17 1

FOR 1.00E-120

CPIJ014785-PA CPIJ014785-PA 425 236 272 91 87 37 1

FOR 1.00E-127

CPIJ008366-PA CPIJ008366-PA 448 235 337 97 70 103 1

1.00E-130

CPIJ005317-PA CPIJ005317-PA 461 234 417 96 56 184 1

FOR 1.00E-114

CPIJ015186-PA CPIJ015186-PA 407 232 385 87 60 154 1

FOR 1.00E-129

CPIJ010112-PA CPIJ010112-PA 455 227 297 98 76 71 1

FOR 1.00E-118

CPIJ006751-PA CPIJ006751-PA 419 226 226 96 100 1 1

FOR 1.00E-128

CPIJ009285-PA CPIJ009285-PA 454 226 365 96 62 140 1

FOR 1.00E-119

CPIJ006022-PA CPIJ006022-PA 424 226 225 95 100 1 1

FOR 1.00E-123

CPIJ004069-PA CPIJ004069-PA 437 223 223 97 100 1 1

FOR 1.00E-124

CPIJ010326-PA CPIJ010326-PA 441 222 280 99 79 36 1

1.00E-125

CPIJ009808-PA CPIJ009808-PA 444 221 376 99 59 156 1

FOR 1.00E-123

CPIJ013941-PA CPIJ013941-PA 435 221 250 99 88 30 1

FOR 1.00E-126

CPIJ018688-PA CPIJ018688-PA 447 218 218 97 100 1 1

FOR 1.00E-109

CPIJ001563-PA CPIJ001563-PA 391 218 297 90 73 80 1

FOR 1.00E-109

CPIJ007659-PA CPIJ007659-PA 389 216 261 87 83 1 1

FOR 1.00E-119

CPIJ018913-PA CPIJ018913-PA 424 212 450 98 47 239 1

1.00E-120

CPIJ014133-PA CPIJ014133-PA 426 212 1017 95 21 61 1

FOR 1.00E-107

CPIJ007381-PA CPIJ007381-PA 384 212 265 86 80 57 1

1.00E-119

CPIJ007404-PA CPIJ007404-PA 421 209 340 98 61 1 1

1.00E-118

CPIJ001782-PA CPIJ001782-PA 419 208 990 98 21 782 1

FOR 1.00E-116

CPIJ013142-PA CPIJ013142-PA 414 208 353 97 59 74 1

FOR 1.00E-102

CPIJ000279-PA CPIJ000279-PA 366 208 247 93 84 40 1

FOR 5.00E-38

CPIJ018780-PA CPIJ018780-PA 153 203 539 52 38 56 1

FOR 1.00E-116

CPIJ002177-PA CPIJ002177-PA 412 202 688 99 29 209 1

FOR 1.00E-115

CPIJ000162-PA CPIJ000162-PA 410 199 261 100 76 63 4

FOR 1.00E-115

CPIJ009351-PA CPIJ009351-PA 410 199 218 97 91 20 1

FOR 1.00E-105

CPIJ002845-PA CPIJ002845-PA 376 198 802 96 25 152 1

FOR 2.00E-95

CPIJ005964-PA CPIJ005964-PA 344 198 198 85 100 1 130

FOR 1.00E-107

CPIJ011589-PA CPIJ011589-PA 384 195 206 99 95 12 1

FOR 4.00E-96

CPIJ005084-PA CPIJ005084-PA 346 193 211 92 91 18 1

FOR 2.00E-98

CPIJ011395-PA CPIJ011395-PA 353 193 679 91 28 490 1

FOR 8.00E-03

CPIJ018769-PA CPIJ018769-PA 37.4 193 849 25 23 102 110

FOR 9.00E-84

CPIJ015682-PA CPIJ015682-PA 305 191 1022 85 19 3 1

6.00E-96

CPIJ011929-PA CPIJ011929-PA 345 187 439 90 43 187 1

3.00E-93

CPIJ015948-PA CPIJ015948-PA 337 185 1353 88 14 1093 1

1.00E-101

CPIJ017415-PA CPIJ017415-PA 363 184 481 97 38 298 1

1.00E-98

CPIJ007327-PA CPIJ007327-PA 354 183 436 95 42 254 1

FOR 7.00E-92

CPIJ010960-PA CPIJ010960-PA 332 178 292 92 61 115 1

FOR 1.00E-100

CPIJ010528-PA CPIJ010528-PA 358 177 177 98 100 1 1

FOR 7.00E-97

CPIJ008049-PA CPIJ008049-PA 348 175 449 98 39 275 1

FOR 9.00E-89

CPIJ020266-PA CPIJ020266-PA 321 174 266 93 65 95 1

9.00E-89

CPIJ004543-PA CPIJ004543-PA 321 174 332 89 52 159 1

FOR 4.00E-97

CPIJ010020-PA CPIJ010020-PA 349 172 266 97 65 95 1

2.00E-73

CPIJ011534-PA CPIJ011534-PA 270 172 619 80 28 449 1

2.00E-86

CPIJ005118-PA CPIJ005118-PA 313 170 365 89 47 199 1

FOR 1.00E-90

CPIJ005868-PA CPIJ005868-PA 327 169 320 95 53 152 1

FOR 7.00E-96

CPIJ012464-PA CPIJ012464-PA 345 168 218 98 77 51 1

FOR 3.00E-91

CPIJ013941-PA CPIJ013941-PA 329 165 250 99 66 86 1

FOR 9.00E-90

CPIJ006763-PA CPIJ006763-PA 324 164 192 98 85 29 1

FOR 2.00E-85

CPIJ005059-PA CPIJ005059-PA 310 163 201 95 81 39 1

FOR 8.00E-88

CPIJ006067-PA CPIJ006067-PA 318 162 238 97 68 77 1

FOR 1.00E-89

CPIJ000161-PA CPIJ000161-PA 324 162 229 96 71 69 1

FOR 1.00E-89

CPIJ018056-PA CPIJ018056-PA 323 161 240 96 67 80 1

5.00E-66

CPIJ003974-PA CPIJ003974-PA 245 161 512 81 31 1 1

FOR 3.00E-63

CPIJ008841-PA CPIJ008841-PA 236 161 308 67 52 146 9

FOR 2.00E-54

CPIJ004924-PA CPIJ004924-PA 207 158 311 68 51 153 1

FOR 5.00E-85

CPIJ004482-PA CPIJ004482-PA 308 156 156 100 100 1 1

FOR 5.00E-90

CPIJ014663-PA CPIJ014663-PA 325 156 430 95 36 275 1

FOR 8.00E-82

CPIJ004794-PA CPIJ004794-PA 298 155 208 99 75 37 1

2.00E-83

CPIJ006068-PA CPIJ006068-PA 303 155 513 98 30 359 1

2.00E-76

CPIJ010352-PA CPIJ010352-PA 280 155 155 93 100 1 1

FOR 1.00E-84

CPIJ008584-PA CPIJ008584-PA 307 154 376 98 41 223 1

5.00E-78

CPIJ001121-PA CPIJ001121-PA 285 153 307 92 50 155 1

5.00E-03

CPIJ012933-PA CPIJ012933-PA 36.2 152 238 23 64 20 1

FOR 4.00E-80

CPIJ011198-PA CPIJ011198-PA 292 149 469 97 32 321 1

FOR 3.00E-76

CPIJ011269-PA CPIJ011269-PA 279 148 165 91 90 18 1

FOR 2.00E-63

CPIJ009623-PA CPIJ009623-PA 237 148 194 79 76 51 1

FOR 2.00E-10

CPIJ002167-PA CPIJ002167-PA 61.6 148 369 27 40 161 1

FOR 3.00E-84

CPIJ009089-PA CPIJ009089-PA 305 147 208 99 71 62 1

FOR 3.00E-81

CPIJ019861-PA CPIJ019861-PA 296 146 369 98 40 224 1

5.00E-78

CPIJ012528-PA CPIJ012528-PA 285 146 260 94 56 115 1

FOR 3.00E-79

CPIJ014540-PA CPIJ014540-PA 289 145 204 100 71 60 1

FOR 3.00E-78

CPIJ010493-PA CPIJ010493-PA 286 145 645 97 22 501 1

FOR 8.00E-78

CPIJ007488-PA CPIJ007488-PA 284 143 452 98 32 310 1

2.00E-75

CPIJ000323-PA CPIJ000323-PA 276 143 458 97 31 20 1

5.00E-74

CPIJ004082-PA CPIJ004082-PA 271 143 215 95 67 73 1

7.00E-73

CPIJ005322-PA CPIJ005322-PA 268 142 142 95 100 1 1

FOR 1.00E-73

CPIJ004888-PA CPIJ004888-PA 270 140 195 97 72 56 1

1.00E-68

CPIJ005493-PA CPIJ005493-PA 254 136 252 93 54 118 1

FOR 1.00E-76

CPIJ011413-PA CPIJ011413-PA 280 135 252 99 54 118 1

FOR 4.00E-74

CPIJ002898-PA CPIJ002898-PA 271 133 547 98 24 415 1

FOR 3.00E-66

CPIJ008003-PA CPIJ008003-PA 246 133 321 94 41 23 1

FOR 5.00E-70

CPIJ016408-PA CPIJ016408-PA 258 132 132 98 100 1 1

FOR 2.00E-70

CPIJ003550-PA CPIJ003550-PA 259 132 657 97 20 526 1

FOR 3.00E-72

CPIJ018444-PA CPIJ018444-PA 265 131 131 98 100 1 1

FOR 4.00E-73

CPIJ003099-PA CPIJ003099-PA 268 130 156 100 83 27 1

FOR 1.00E-66

CPIJ016691-PA CPIJ016691-PA 246 128 488 89 26 288 1

FOR 3.00E-56

CPIJ001686-PA CPIJ001686-PA 212 127 346 81 37 212 1

FOR 3.00E-66

CPIJ018866-PA CPIJ018866-PA 245 124 319 97 39 196 3

FOR 7.00E-71

CPIJ017344-PA CPIJ017344-PA 261 124 547 96 23 423 1

3.00E-63

CPIJ005339-PA CPIJ005339-PA 235 123 999 95 12 570 1

2.00E-64

CPIJ009364-PA CPIJ009364-PA 239 123 261 94 47 139 1

FOR 6.00E-48

CPIJ003536-PA CPIJ003536-PA 184 123 355 80 35 234 1

FOR 1.00E-53

CPIJ011711-PA CPIJ011711-PA 203 120 1348 88 9 3 1

5.00E-59

CPIJ001670-PA CPIJ001670-PA 221 118 872 94 14 755 1

FOR 3.00E-61

CPIJ009776-PA CPIJ009776-PA 228 116 301 98 39 186 1

2.00E-59

CPIJ010191-PA CPIJ010191-PA 223 116 2111 90 5 1996 1

FOR 2.00E-64

CPIJ000363-PA CPIJ000363-PA 239 115 287 100 40 173 1

FOR 2.00E-58

CPIJ006209-PA CPIJ006209-PA 219 115 511 97 23 397 1

8.00E-64

CPIJ005007-PA CPIJ005007-PA 237 115 1010 96 11 896 1

FOR 1.20E-01

CPIJ008074-PA CPIJ008074-PA 32.3 115 269 27 43 132 71

2.00E-56

CPIJ012970-PA CPIJ012970-PA 213 113 287 97 39 175 1

2.00E-55

CPIJ018629-PA CPIJ018629-PA 209 112 219 90 51 108 1

FOR 2.00E-53

CPIJ014325-PA CPIJ014325-PA 204 112 115 84 97 4 88

FOR 5.00E-40

CPIJ003335-PA CPIJ003335-PA 158 111 225 70 49 115 1

FOR 1.00E-58

CPIJ018118-PA CPIJ018118-PA 219 109 538 97 20 430 1

8.00E-58

CPIJ010473-PA CPIJ010473-PA 217 109 332 94 33 224 1

FOR 2.00E-57

CPIJ011778-PA CPIJ011778-PA 215 107 176 100 61 70 1

FOR 2.00E-64

CPIJ004713-PA CPIJ004713-PA 239 107 107 98 100 1 1

FOR 4.00E-56

CPIJ004203-PA CPIJ004203-PA 211 107 227 97 47 123 1

FOR 5.00E-52

CPIJ002330-PA CPIJ002330-PA 197 107 137 95 78 32 1

FOR 3.00E-57

CPIJ010692-PA CPIJ010692-PA 215 106 124 99 85 19 1

FOR 2.00E-58

CPIJ017373-PA CPIJ017373-PA 219 106 480 98 22 375 1

FOR 1.00E-56

CPIJ006031-PA CPIJ006031-PA 213 106 406 95 26 301 1

FOR 1.00E-57

CPIJ015042-PA CPIJ015042-PA 216 106 149 94 71 44 1

FOR 6.00E-51

CPIJ013872-PA CPIJ013872-PA 194 106 243 88 44 138 1

3.00E-59

CPIJ006739-PA CPIJ006739-PA 221 105 110 99 95 6 1

FOR 3.00E-57

CPIJ008184-PA CPIJ008184-PA 215 104 144 99 72 41 1

5.00E-58

CPIJ000484-PA CPIJ000484-PA 218 104 162 97 64 59 1

FOR 7.00E-33

CPIJ011422-PA CPIJ011422-PA 137 104 172 60 60 68 1

FOR 2.00E-53

CPIJ008265-PA CPIJ008265-PA 202 103 148 99 70 46 1

FOR 3.00E-50

CPIJ002453-PA CPIJ002453-PA 192 103 190 95 54 88 1

FOR 1.00E-41

CPIJ018340-PA CPIJ018340-PA 163 103 286 88 36 187 1

1.00E-54

CPIJ009076-PA CPIJ009076-PA 206 102 102 93 100 1 1

5.00E-48

CPIJ007542-PA CPIJ007542-PA 184 102 100 90 102 1 1

1.00E-53

CPIJ000323-PA CPIJ000323-PA 203 101 458 99 22 236 1

2.00E-54

CPIJ008169-PA CPIJ008169-PA 206 101 101 98 100 1 1



91.21893

Best

Orientatio match to

Number n of AEGY- Length of First

of assemble PEP Extent of best % Match residue of

segments d output database E value Match Score match match % identity length match

32 FOR 2.00E-28 AAEL009219-RA 122

predicted protein 361 1345 29 27 0

1 FOR 0.00E+00 AAEL004563-RA 632

26S protease regulatory subunit S10b 323 393 98 82 68

1 FOR 1.00E-180 AAEL010602-RA 627

starch branching enzyme ii 323 684 90 47 285

1 FOR 1.00E-177 AAEL006582-RB 617 317 999

calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium 95 32 632

1 FOR 0.00E+00

atp-citrate synthase AAEL004297-RA 633 316 1127 98 28 682

1 FOR 1.00E-140 protein

conserved hypothetical AAEL005067-RA 492 314 644 75 49 183

1 FOR 1.00E-166 AAEL003393-RA 581

atp synthase beta subunit 306 504 97 61 67

1 FOR malic enzyme 1.00E-170 AAEL005790-RA 592 306 660 93 46 265

1 FOR 1.00E-140 AAEL001816-RA 494

glucosyl/glucuronosyl transferases 301 517 77 58 2

1 FOR actin 1.00E-174 AAEL011197-RB 605 302 376 99 80 56

1 FOR 1.00E-163 AAEL007660-RA 568

suppressor of actin (sac) 302 594 90 51 239

1 FOR 1.00E-153 mitochondrial (beta- ketothiolase) (acetyl-coa

3-ketoacyl-coa thiolase,AAEL010697-RA 536 302 398 87 76 97

11 FOR 1.00E-100 protein

conserved hypothetical AAEL006126-RA 360 305 2087 57 15 340

1 FOR 2.00E-03 AAEL008183-RA 39.3

t complex protein 123 961 26 13 405

1 FOR 1.00E-174 AAEL004500-RB

eukaryotic translation elongation factor 605 299 844 97 35 358

1 FOR 1.00E-142 protein

conserved hypothetical AAEL009955-RA 499 298 3321 79 9 2861

1 FOR 1.00E-162 AAEL008517-RA 568

elongation factor tu (ef-tu) 294 463 95 63 41

1 FOR 1.00E-148 AAEL002048-RA 519

histidyl-tRNA synthetase 295 514 87 57 29

1 FOR 1.00E-149 AAEL010276-RA 524

aminomethyltransferase 291 412 89 71 92

1 FOR 3.50E-01 protein

conserved hypothetical AAEL013194-RA 31.6 175 552 20 32 57

1 FOR 1.00E-123 reductase complex core

ubiquinol-cytochrome c AAEL005269-RB 435 protein 280 441 78 63 1

1 FOR zinc metalloprotease

protease m11.00E-109 AAEL003227-RA 391 279 910 64 31 526

1 FOR 1.00E-121 AAEL001194-RA 429

fatty acid synthase 273 2422 76 11 2132

1 FOR 1.00E-139 AAEL002841-RA 489

3-hydroxyacyl-coa dehyrogenase 270 305 88 89 36

2 FOR 4.00E-96 protein

conserved hypothetical AAEL003791-RA 347 270 565 69 48 233

1 FOR 1.00E-145 AAEL013676-RA 509

26S protease regulatory subunit 265 403 97 66 4

1 FOR 1.00E-141 AAEL003606-RA 495

purine biosynthesis protein 6, pur6 265 427 91 62 162

2 FOR 1.00E-122 protein

conserved hypothetical AAEL007447-RA 433 268 1270 82 21 710

1 FOR serine protease8.00E-74 AAEL006586-RA 272 269 314 49 86 47

1 FOR 1.00E-36 protein

conserved hypothetical AAEL001414-RB 149 262 491 31 53 226

1 FOR 1.00E-140 AAEL008366-RA 494

pyruvate dehydrogenase 264 438 89 60 175

46 FOR 3.00E-27

hypothetical protein AAEL014367-RA 117 262 2055 34 13 473

1 FOR 1.00E-136

endoU protein, putative AAEL009629-RA 479 257 570 89 45 314

1 FOR 1.00E-136

endoU protein, putative AAEL009629-RA 479 257 570 89 45 314

1 FOR 1.00E-127 AAEL013694-RA laminin receptor) (colon carcinoma 87

40S ribosomal protein sa (P40) (34/67 kda450 257 288 89 36

1 FOR 1.00E-155

tyrosine kinase receptorAAEL000850-RA 542 269 706 97 38 438

1 FOR 4.00E-01

zinc carboxypeptidase AAEL001842-RA 31.2 58 367 32 16 288

2 FOR 3.00E-90

slender lobes, putative AAEL002774-RB 327 267 1239 70 22 975

1 FOR 1.00E-126 protein

conserved hypothetical AAEL011113-RA 446 240 392 88 61 135

2 FOR 4.00E-79 AAEL015374-RA 290

restin (cytoplasmic linker protein-170) (clip-170) 156 285 96 55 21

1 FOR enzyme beta subunit (tp-beta)

trifunctional 1.00E-133 AAEL002296-RA 468 239 469 96 51 231

1 FOR 4.00E-59 protein

conserved hypothetical AAEL012227-RA 223 234 235 57 100 19

1 FOR 1.00E-105 protein, L46, putative

mitochondrial ribosomalAAEL009833-RA 378 236 267 80 88 33

1 FOR 1.00E-122

malate dehydrogenase AAEL008166-RA 433 234 419 94 56 185

1 FOR 1.00E-126 protein

conserved hypothetical AAEL006646-RA 446 234 417 93 56 184

1 FOR galactokinase 1.00E-106 AAEL002781-RB 381 229 398 81 58 165

1 FOR 1.00E-124

ribosomal protein L5 AAEL004325-RA 440 227 297 95 76 71

1 FOR synthase AAEL012035-RA 394

vacuolar atp1.00E-110subunit e 226 226 89 100 1

1 FOR 1.00E-118 AAEL004997-RA 420

U3 small nucleolar ribonucleoprotein protein imp4 226 417 88 54 192

1 FOR 1.00E-114 AAEL000951-RA 405

elongation factor 1-beta2 222 224 91 99 4

1 FOR 2.00E-71 AAEL007383-RD 264

secreted ferritin G subunit precursor, putative 225 221 62 102 1

1 FOR 1.00E-134 AAEL010168-RB 474

40S ribosomal protein S2 240 275 99 87 36

1 FOR actin 1.00E-125 AAEL011197-RB 444 221 376 99 59 156

1 FOR 1.00E-115 AAEL008192-RB 408

40S ribosomal protein S3 221 256 95 86 43

1 FOR 1.00E-119 AAEL002534-RA 424

60S ribosomal protein L10 216 219 91 99 1

1 FOR 1.00E-108 AAEL008848-RA 387

atp synthase gamma subunit 218 297 87 73 80

1 FOR 1.00E-81 protein

conserved hypothetical AAEL005401-RB 298 217 275 67 79 7

1 FOR 1.00E-119 protein

conserved hypothetical AAEL012912-RA 424 212 450 98 47 239

7 FOR saposin 1.00E-106 AAEL003046-RA 379 212 1017 80 21 31

1 FOR 6.00E-93 protein

conserved hypothetical AAEL002165-RA 335 212 274 72 77 61

4 FOR 1.00E-117 AAEL001041-RA 415

guanine nucleotide-binding protein beta 3 (g protein beta3)

209 340 97 61 1

1 FOR importin 1.00E-104 AAEL005390-RA 372 208 990 84 21 783

2 FOR 1.00E-112 AAEL011195-RA

mitochondrial phosphate carrier protein 399 208 211 93 99 4

1 FOR 2.00E-05

histone H1, putative AAEL011906-RA 45.1 75 201 42 37 81

1 FOR 1.00E-98

ribosomal protein S6 AAEL000032-RC 354 232 346 83 67 118

2 FOR 1.00E-112 AAEL007718-RA 398

translation initiation factor 3, subunit S9, putative 202 688 93 29 209

1 FOR 1.00E-115 AAEL000987-RA 410

60S ribosomal protein L8 199 261 100 76 63

1 FOR 1.00E-108

Mob3B protein, putativeAAEL007325-RA 387 202 248 90 81 46

2 FOR 9.00E-90 AAEL000417-RA 325

monocarboxylate transporter 173 753 95 23 124

1 FOR 1.00E-171 AAEL012062-RB 597

na+/k+ atpase alpha subunit 301 1001 96 30 701

1 FOR 1.00E-101 AAEL008103-RB 363

40S ribosomal protein S8 195 206 92 95 12

1 FOR 1.00E-87 protein

conserved hypothetical AAEL008417-RA 317 190 209 82 91 18

1 FOR 1.00E-72 protein

conserved hypothetical AAEL006549-RA 268 192 674 70 28 487

1 FOR 1.00E-155 AAEL009859-RA 543

nucleolar gtp-binding protein 302 652 90 46 272

8 FOR 5.00E-63 AAEL009241-RA 236

translation initiation factor if-2 198 998 68 20 3

1 FOR 2.00E-76 reductase complex core

ubiquinol-cytochrome c AAEL005269-RB 280 protein 189 441 75 43 187

1 FOR 3.00E-68 protein

conserved hypothetical AAEL002260-RA 254 182 1296 68 14 1094

1 FOR 1.00E-97

glycosyl transferase AAEL000559-RA 350 184 484 92 38 301

1 FOR 2.00E-94 AAEL010065-RA

protein disulfide-isomerase A6 precursor 340 174 437 92 40 264

1 FOR 4.00E-82 protein

conserved hypothetical AAEL001913-RA 299 171 326 83 52 154

1 FOR 1.00E-100 AAEL006785-RB 358

60S ribosomal protein L18a 177 177 98 100 1

1 FOR hexokinase 2.00E-94 AAEL009387-RA 340 174 453 97 38 280

1 FOR 2.00E-72

hypothetical protein AAEL007134-RA 267 176 267 76 66 92

1 FOR ribosomal protein, S35, putative

mitochondrial9.00E-80 AAEL009217-RA 291 174 329 78 53 156

1 FOR 1.00E-94 AAEL012585-RA 340

60S ribosomal protein L7 172 263 94 65 92

1 FOR 2.00E-39 protein

conserved hypothetical AAEL012102-RA 157 155 632 57 25 478

1 FOR 1.00E-51 AAEL000541-RB 198

fasciclin, putative 168 375 60 45 221

1 FOR 5.00E-79 AAEL010514-RA 288

aminoacyl-tRNA synthetase auxiliary protein, 43kD, putative

169 322 84 52 154

1 FOR 7.60E-01 protein

conserved hypothetical AAEL013195-RA 29.3 26 386 50 7 318

1 FOR 3.00E-83 AAEL008192-RB 302

40S ribosomal protein S3 165 256 93 64 99

1 FOR 3.00E-88 AAEL009496-RA 319

40S ribosomal protein S7 164 192 96 85 29

1 FOR 3.00E-67 protein

conserved hypothetical AAEL008454-RB 249 162 200 75 81 39

1 FOR atp synthase b chain

mitochondrial7.00E-81 AAEL005610-RA 295 162 238 90 68 77

1 FOR 2.00E-82 protein

conserved hypothetical AAEL000985-RA 300 164 227 92 72 67

1 FOR 1.00E-75 AAEL000934-RA 277

clathrin light chain 166 288 83 58 123

1 FOR 3.00E-47 protein

conserved hypothetical AAEL001765-RA 183 122 710 77 17 6

1 FOR cis-trans isomerase f, ppif

peptidyl-prolyl2.00E-93 AAEL011758-RA 337 169 206 94 82 40

1 FOR 1.00E-11

hypothetical protein AAEL012086-RA 65.1 158 498 25 32 341

1 FOR 2.00E-79 AAEL010756-RA 290

40S ribosomal protein S19 156 156 92 100 1

1 FOR 7.00E-86 AAEL011288-RA 311

elongation factor 1 gamma 156 432 89 36 277

2 FOR 9.00E-80 AAEL012113-RA

vacuolar atp synthase proteolipid subunit 291 155 208 96 75 47

1 FOR 3.00E-84 AAEL005617-RA 306

utp-glucose-1-phosphate uridylyltransferase 2 155 513 98 30 359

1 FOR 1.00E-64 protein

conserved hypothetical AAEL012010-RA 240 148 150 81 99 2

1 FOR 1.00E-78 AAEL013158-RA 287

40S ribosomal protein S3a 154 270 90 57 117

1 FOR 1.00E-52 protein

conserved hypothetical AAEL004509-RA 201 149 305 66 49 154

2 FOR 2.00E-51 AAEL000010-RB 196

ribosomal protein L36, putative 99 113 97 88 15

1 FOR 1.00E-74 AAEL003564-RA 273

threonine dehydratase/deaminase 149 467 89 32 319

1 FOR NADH:ubiquinone oxidoreductase

mitochondrial1.00E-63 AAEL013876-RA 237 B14.7147 subunit, putative

167 76 88 18

1 FOR 9.00E-29 protein

conserved hypothetical AAEL005086-RA 121 68 169 82 40 54

1 FOR 4.00E-10 AAEL005977-RA 60.5

chondroitin 4-sulfotransferase 204 386 23 53 181

1 FOR 3.00E-84 AAEL003503-RA 305

ras-related protein Rab-7 147 208 99 71 62

1 FOR citrate synthase2.00E-79 AAEL002956-RA 290 143 467 97 31 320

1 FOR 1.00E-71 protein

conserved hypothetical AAEL007229-RA 263 145 254 87 57 114

1 FOR 6.00E-77 AAEL012733-RA 281

60S ribosomal protein L19 145 170 95 85 26

1 FOR 5.00E-39

amp dependent ligase AAEL005740-RA 155 82 617 89 13 523

1 FOR 9.20E-01

hypothetical protein AAEL009385-RA 28.5 54 984 31 5 258

3 FOR 2.00E-63 protein

conserved hypothetical AAEL014318-RA 236 147 531 86 28 91

1 FOR rab11 2.00E-73 AAEL009317-RA 270 143 215 94 67 73

1 FOR 2.00E-53 protein

conserved hypothetical AAEL008750-RA 203 144 138 69 104 1

1 FOR 1.00E-73 AAEL001759-RA 270

40S ribosomal protein S9 140 195 97 72 56

1 FOR 6.00E-39 protein

conserved hypothetical AAEL012227-RA 155 138 235 62 59 105

1 FOR 3.00E-76 AAEL014548-RA 279

peroxiredoxins, prx-1, prx-2, prx-3 135 257 98 53 121

1 FOR 3.00E-71 AAEL007153-RA 262

5'-AMP-activated protein kinase, catalytic alpha-1 chain

133 545 93 24 413

3 FOR annexin x 1.00E-62 AAEL005407-RC 233 133 322 85 41 23

1 FOR 3.00E-59 AAEL009653-RA 222

40S ribosomal protein S30 132 132 84 100 1

1 FOR 3.00E-03

hypothetical protein AAEL006395-RA 36.6 92 3028 29 3 766

1 FOR RNA polymerase subunit rpb6

DNA-directed3.00E-71 AAEL003552-RA 262 131 131 96 100 1

1 FOR 3.00E-73 AAEL013536-RA 268

ubiquitin (ribosomal protein L40) 130 156 100 83 27

2 FOR 1.00E-33 AAEL002665-RA 137

matrix metalloproteinase 128 492 49 26 304

1 FOR 3.00E-28 protein

conserved hypothetical AAEL003107-RA 119 133 342 43 39 198

1 FOR isomerase

peptidylprolyl 5.00E-57 AAEL012809-RA 214 124 318 82 39 195

1 FOR cathepsin l 5.00E-67 AAEL006389-RA 248 123 538 91 23 413

1 FOR 8.40E-01 protein

conserved hypothetical AAEL015080-RA 28.1 33 564 33 6 506

1 FOR 1.00E-56

anamorsin, putative AAEL001501-RA 213 123 254 86 48 135

1 FOR 1.00E-24 protein

conserved hypothetical AAEL006971-RA 107 114 354 48 32 232

4 FOR 6.00E-39

hypothetical protein AAEL003671-RA 154 124 1344 67 9 1225

1 FOR 6.00E-51 AAEL007080-RA 194

glycerol-3-phosphate acyltransferase 118 881 81 13 764

1 FOR 1.00E-60 AAEL011429-RA

clathrin coat adaptor ap3 medium chain 226 116 414 97 28 299

1 FOR 3.00E-34 protein

conserved hypothetical AAEL006126-RA 139 110 2087 51 5 1978

1 FOR 4.00E-47 AAEL014219-RA 181

nicotinate phosphoribosyltransferase 91 227 94 40 137

1 FOR beta subunit

atp synthase 2.00E-58 AAEL003393-RA 219 115 504 97 23 390

1 FOR 1.00E-59 AAEL010256-RA 223

E3 ubiquitin ligase 141 868 79 16 728

1 FOR 3.00E-83 AAEL014204-RA 303

6-phosphogluconolactonase 184 251 80 73 68

1 FOR 8.00E-50 AAEL009101-RA 190

eukaryotic translation initiation factor 3f, eif3f 113 287 85 39 175

1 FOR 3.00E-34 AAEL007951-RA 138

glutathione-s-transferase theta, gst 110 222 59 50 108

1 FOR 3.00E-78 protein

conserved hypothetical AAEL005358-RA 286 202 387 73 52 191

1 FOR 4.00E-13 protein

conserved hypothetical AAEL004541-RA 68.6 104 225 37 46 119

1 FOR amidase 2.00E-55 AAEL005477-RA 209 109 566 91 19 458

1 FOR 1.00E-47 protein

conserved hypothetical AAEL007259-RB 183 106 333 77 32 225

1 FOR 2.00E-57 AAEL008363-RD 215

transcription initiation factor TFIID subunit 12 107 182 100 59 76

1 FOR 3.00E-53 protein

conserved hypothetical AAEL014681-RA 202 107 106 84 101 1

1 FOR 4.00E-49 AAEL006441-RA 188

proteasome subunit beta type 6,9 107 228 85 47 123

1 FOR 1.00E-50 AAEL002337-RA 193

prefoldin, subunit, putative 107 138 88 78 32

1 FOR 2.00E-56 AAEL006698-RA 212

60S ribosomal protein L31 106 124 98 85 19

1 FOR 1.00E-53 AAEL001588-RA 203

glutamate carboxypeptidase 105 483 91 22 378

1 FOR 6.00E-47 protein

conserved hypothetical AAEL007881-RA 181 113 415 76 27 303

1 FOR 2.00E-05

hypothetical protein AAEL005298-RA 43.5 48 53 52 91 6

1 FOR 3.00E-18

hypothetical protein AAEL005882-RA 85.9 79 228 51 35 136

1 FOR 1.00E-59 AAEL006647-RA 223

dynein light chain, putative 105 111 100 95 7

1 FOR 7.00E-54 putative

ribosomal protein L35A,AAEL000823-RA 204 104 172 94 60 70

1 FOR 8.00E-52 AAEL009066-RA 197

symbol, putative 104 162 86 64 59

1 FOR 1.00E-07

hypothetical protein AAEL006968-RA 53.1 61 381 44 16 18

1 FOR 3.00E-53 AAEL003427-RA 202

ribosomal protein S9, putative 103 148 97 70 46

1 FOR 2.00E-50 AAEL007699-RB 192

60S ribosomal protein L9 103 190 94 54 88

1 FOR 4.00E-29 protein

conserved hypothetical AAEL013138-RA 121 109 289 67 38 113

1 FOR 1.00E-46 protein

conserved hypothetical AAEL013960-RA 179 100 100 83 100 1

1 FOR 5.00E-35 protein

conserved hypothetical AAEL004833-RA 141 103 105 66 98 3

2 FOR 1.00E-41 protein

conserved hypothetical AAEL014318-RA 163 105 531 83 20 136

1 FOR 6.50E-01

hypothetical protein AAEL008551-RA 28.1 27 640 48 4 252

Best

First Number match to Length of First

residue of of AGPROT Extent of best % Match residue of

sequence segments database E value Match Score match match % identity length match

0 1.00E-21

21 AGAP009669-PA AGAP009669-PA 99.8 337 724 30 47 2

1 0.00E+00

1 AGAP001407-PA AGAP001407-PA 629 323 397 98 81 72

1 1.00E-174

1 AGAP010428-PA AGAP010428-PA 605 323 682 86 47 284

1 1.00E-171

1 AGAP006186-PD AGAP006186-PD 595 317 1018 91 31 632

1 1.00E-176

1 AGAP010156-PA AGAP010156-PA 611 316 1082 93 29 637

1 1.00E-117

1 AGAP005299-PA AGAP005299-PA 415 317 512 64 62 118

1 1.00E-83

1 AGAP012081-PA AGAP012081-PA 305 161 217 95 74 57

1 1.00E-156

1 AGAP000184-PA AGAP000184-PA 546 306 576 85 53 181

4 4.00E-92

1 AGAP008401-PA AGAP008401-PA 333 290 1042 54 28 28

1 1.00E-174

1 AGAP000651-PA AGAP000651-PA 605 302 376 99 80 56

1 1.00E-112

1 AGAP000891-PA AGAP000891-PA 399 304 590 64 52 239

1 1.00E-150

1 AGAP006821-PA AGAP006821-PA 527 302 398 86 76 97

1 2.00E-90

10 AGAP004203-PB AGAP004203-PB 328 299 2034 51 15 337

168 1.00E-162

2 AGAP004192-PA AGAP004192-PA 566 300 659 95 46 346

1 1.00E-171

1 AGAP009441-PA AGAP009441-PA 595 299 844 95 35 358

1 1.00E-102

1 AGAP001826-PA AGAP001826-PA 367 297 3331 60 9 2872

17 1.00E-162

1 AGAP006996-PA AGAP006996-PA 567 292 466 95 63 45

1 1.00E-131

1 AGAP000735-PA AGAP000735-PA 462 270 506 79 53 46

1 1.00E-138

1 AGAP001124-PA AGAP001124-PA 485 291 415 81 70 95

5 1.00E-131

2 AGAP006625-PA AGAP006625-PA 464 278 304 80 91 3

1 1.00E-113

1 AGAP006099-PA AGAP006099-PA 404 279 439 72 64 1

1 1.00E-26

1 AGAP003695-PA AGAP003695-PA 115 175 1746 32 10 496

1 1.00E-112

1 AGAP009176-PA AGAP009176-PA 399 271 2446 72 11 2158

1 2.00E-32

1 AGAP007784-PA AGAP007784-PA 134 264 771 32 34 389

1 5.00E-65

1 AGAP000261-PA AGAP000261-PA 243 233 574 58 41 226

3 1.00E-143

1 AGAP007243-PA AGAP007243-PA 502 262 403 97 65 7

1 1.00E-126

1 AGAP000180-PA AGAP000180-PA 446 264 427 82 62 162

1 6.00E-59

1 AGAP007808-PA AGAP007808-PA 223 266 1216 52 22 294

1 6.00E-59

1 AGAP003252-PA AGAP003252-PA 223 274 369 40 74 100

1 1.00E-17

1 AGAP007453-PA AGAP007453-PA 85.9 285 465 24 61 101

1 1.00E-129

1 AGAP003136-PA AGAP003136-PA 457 263 415 82 63 152

2 1.00E-19

10 AGAP009669-PA AGAP009669-PA 92.4 301 724 30 42 4

1 1.00E-121

1 AGAP002925-PA AGAP002925-PA 429 256 524 78 49 268

1 1.00E-121

1 AGAP002925-PA AGAP002925-PA 429 256 524 78 49 268

1 1.00E-105

1 AGAP011777-PA AGAP011777-PA 377 256 285 74 90 37

1 1.00E-154

1 AGAP011648-PA AGAP011648-PA 540 269 706 97 38 438

39 1.00E-110

1 AGAP001721-PA AGAP001721-PA 394 247 284 80 87 41

3 2.00E-62

1 AGAP003457-PA AGAP003457-PA 234 186 1046 69 18 862

1 1.00E-125

1 AGAP001153-PA AGAP001153-PA 442 251 402 85 62 139

1 8.00E-90

2 AGAP009210-PA AGAP009210-PA 325 196 1710 85 11 130

1 1.00E-118

1 AGAP011827-PA AGAP011827-PA 418 239 380 86 63 157

4 1.00E-32

1 AGAP003612-PA AGAP003612-PA 135 265 270 37 98 16

1 5.00E-96

1 AGAP006684-PA AGAP006684-PA 345 239 271 73 88 34

1 1.00E-120

1 AGAP001903-PA AGAP001903-PA 426 235 337 91 70 103

1 1 1.00E-124

AGAP010020-PA AGAP010020-PA 439 234 417 91 56 184

1 1 2.00E-93

AGAP002914-PA AGAP002914-PA 337 232 399 69 58 166

1 1 4.00E-94

AGAP009031-PA AGAP009031-PA 339 182 324 90 56 70

1 1 1.00E-106

AGAP002401-PA AGAP002401-PA 379 226 226 84 100 1

1 1 1.00E-104

AGAP009968-PA AGAP009968-PA 374 226 237 76 95 12

5 1 1.00E-104

AGAP010613-PA AGAP010613-PA 373 222 222 85 100 4

1 1 2.00E-48

AGAP002464-PA AGAP002464-PA 187 217 229 47 95 25

1 1 1.00E-129

AGAP003768-PA AGAP003768-PA 455 240 274 94 88 35

1 1 1.00E-125

AGAP000651-PA AGAP000651-PA 444 221 376 99 59 156

1 1 1.00E-109

AGAP001910-PA AGAP001910-PA 389 200 244 97 82 30

1 1 1.00E-120

AGAP002395-PA AGAP002395-PA 424 218 219 91 100 1

1 1 1.00E-104

AGAP007966-PA AGAP007966-PA 372 218 297 85 73 80

1 1 4.00E-09

AGAP003304-PA AGAP003304-PA 57 35 87 71 40 53

1 1 1.00E-118

AGAP011252-PA AGAP011252-PA 418 212 436 96 49 225

1 8 1.00E-42

AGAP001082-PA AGAP001082-PA 168 151 957 50 16 23

1 1 1.00E-85

AGAP003099-PA AGAP003099-PA 311 214 272 69 79 59

1 4 1.00E-113

AGAP005913-PA AGAP005913-PA 404 209 340 94 61 1

1 1 3.00E-63

AGAP009571-PA AGAP009571-PA 236 176 947 61 19 774

1 1 1.00E-109

AGAP003586-PA AGAP003586-PA 390 208 370 90 56 94

1 3 2.00E-78

AGAP006037-PA AGAP006037-PA 287 234 390 67 60 2

1 1 2.00E-68

AGAP002919-PB AGAP002919-PB 254 301 424 54 71 119

1 2 1.00E-106

AGAP012140-PA AGAP012140-PA 378 202 683 88 30 201

4 1 1.00E-114

AGAP005802-PA AGAP005802-PA 404 199 261 97 76 63

1 1 1.00E-106

AGAP007872-PA AGAP007872-PA 379 199 221 86 90 23

1 2 1.00E-88

AGAP003206-PA AGAP003206-PA 320 174 763 93 23 135

1 1 1.00E-166

AGAP002858-PA AGAP002858-PA 578 301 1000 93 30 700

1 1 1.00E-64

AGAP002437-PA AGAP002437-PA 241 134 135 89 99 2

1 1 1.00E-64

AGAP004110-PA AGAP004110-PA 241 181 197 74 92 18

2 1 2.00E-38

AGAP006092-PA AGAP006092-PA 154 196 692 41 28 500

1 1 1.00E-141

AGAP007050-PA AGAP007050-PA 497 302 652 81 46 272

1 7 4.00E-25

AGAP004824-PA AGAP004824-PA 109 108 871 55 12 5

1 1 4.00E-72

AGAP006099-PA AGAP006099-PA 266 187 439 69 43 187

1 1 1.00E-64

AGAP006517-PA AGAP006517-PA 241 161 1411 68 11 1162

1 1 2.00E-88

AGAP011324-PA AGAP011324-PA 320 179 477 86 38 299

7 1 4.00E-85

AGAP001919-PA AGAP001919-PA 309 183 445 79 41 263

5 1 1.00E-67

AGAP009156-PA AGAP009156-PA 251 175 319 70 55 144

1 1 3.00E-96

AGAP012284-PA AGAP012284-PA 346 177 177 93 100 1

2 1 6.00E-58

AGAP011208-PA AGAP011208-PA 218 115 248 93 46 134

3 1 2.00E-64

AGAP002012-PA AGAP002012-PA 240 158 268 75 59 111

1 1 5.00E-70

AGAP006802-PA AGAP006802-PA 258 175 340 69 51 160

1 1 1.00E-87

AGAP008916-PA AGAP008916-PA 317 171 262 89 65 93

7 1 7.00E-03

AGAP008698-PA AGAP008698-PA 35.8 106 2083 26 5 8

3 1 3.00E-29

AGAP010821-PA AGAP010821-PA 123 175 363 44 48 192

1 1 2.00E-80

AGAP010586-PA AGAP010586-PA 293 170 334 85 51 165

15 1 3.10E+00

AGAP001827-PA AGAP001827-PA 26.9 34 917 38 4 696

1 1 3.00E-78

AGAP001910-PA AGAP001910-PA 286 144 244 97 59 86

1 1 5.00E-86

AGAP010592-PA AGAP010592-PA 311 164 192 94 85 29

1 1 4.00E-73

AGAP002320-PA AGAP002320-PA 268 163 201 82 81 39

1 1 3.00E-80

AGAP001138-PA AGAP001138-PA 292 162 236 87 69 75

1 1 7.00E-74

AGAP005801-PA AGAP005801-PA 271 154 234 86 66 85

3 1 2.00E-64

AGAP010608-PA AGAP010608-PA 239 124 219 92 57 96

37 1 1.00E-40

AGAP005053-PA AGAP005053-PA 160 125 718 64 17 1

1 1 3.00E-86

AGAP000462-PA AGAP000462-PA 312 167 175 86 95 9

1 1 2.00E-05

AGAP004877-PA AGAP004877-PA 44.3 126 882 24 14 135

1 1 3.00E-73

AGAP010933-PA AGAP010933-PA 269 154 158 83 97 1

1 1 3.00E-83

AGAP000883-PA AGAP000883-PA 302 156 427 87 37 272

1 2 2.00E-79

AGAP009334-PA AGAP009334-PA 289 155 211 96 73 50

1 1 3.00E-83

AGAP001257-PA AGAP001257-PA 302 155 513 97 30 359

5 1 2.00E-57

AGAP012587-PA AGAP012587-PA 216 144 155 71 93 12

1 1 3.00E-69

AGAP003532-PA AGAP003532-PA 256 154 269 83 57 117

1 1 1.00E-43

AGAP009433-PA AGAP009433-PA 170 154 314 59 49 151

1 2 2.00E-51

AGAP002921-PA AGAP002921-PA 196 99 115 98 86 17

1 1 5.00E-72

AGAP003571-PA AGAP003571-PA 265 149 464 85 32 314

1 1 3.00E-63

AGAP007208-PA AGAP007208-PA 236 147 166 72 89 17

4 1 4.00E-19

AGAP004150-PA AGAP004150-PA 89.4 69 119 60 58 50

1 1 4.00E-12

AGAP005721-PA AGAP005721-PA 66.6 208 400 21 52 195

1 1 5.00E-73

AGAP001617-PA AGAP001617-PA 268 132 194 95 68 62

1 1 1.00E-81

AGAP012048-PA AGAP012048-PA 296 146 466 97 31 321

1 1 3.00E-63

AGAP009288-PA AGAP009288-PA 236 145 253 77 57 114

1 1 3.00E-76

AGAP004422-PA AGAP004422-PA 278 145 190 95 76 46

1 1 6.00E-62

AGAP008596-PA AGAP008596-PA 231 166 690 74 24 525

1 1 5.00E-74

AGAP003556-PA AGAP003556-PA 271 139 417 93 33 273

1 2 2.00E-43

AGAP006063-PA AGAP006063-PA 169 163 584 55 28 91

1 1 2.00E-46

AGAP004559-PA AGAP004559-PA 179 98 183 92 54 73

1 1 8.00E-37

AGAP002328-PA AGAP002328-PA 147 142 141 52 101 1

1 1 1.00E-73

AGAP005061-PB AGAP005061-PB 270 140 195 96 72 56

2 1 3.00E-16

AGAP003612-PA AGAP003612-PA 79.3 166 270 33 61 110

1 1 8.00E-76

AGAP007543-PA AGAP007543-PA 277 135 258 97 52 124

1 1 2.00E-67

AGAP002686-PA AGAP002686-PA 249 135 550 89 25 416

1 4 3.00E-61

AGAP003721-PA AGAP003721-PA 229 133 321 87 41 23

1 1 3.00E-48

AGAP000654-PA AGAP000654-PA 185 131 131 74 100 1

10 5 1.00E-64

AGAP004192-PA AGAP004192-PA 239 133 659 89 20 527

1 1 1.00E-70

AGAP005873-PA AGAP005873-PA 259 131 131 94 100 1

1 1 3.00E-23

AGAP002599-PA AGAP002599-PA 102 50 229 100 22 27

1 2 1.00E-16

AGAP006904-PC AGAP006904-PC 80.5 118 570 36 21 306

2 1 2.00E-11

AGAP004334-PA AGAP004334-PA 63.2 127 332 25 38 200

3 1 6.00E-46

AGAP000725-PA AGAP000725-PA 177 123 322 73 38 201

1 1 4.00E-64

AGAP012900-PA AGAP012900-PA 238 124 135 86 92 11

78 1 7.10E-01

AGAP002529-PA AGAP002529-PA 28.1 63 984 30 6 657

1 1 9.00E-52

AGAP008883-PA AGAP008883-PA 197 122 254 77 48 136

4 1 1.00E-04

AGAP009110-PA AGAP009110-PA 40.4 117 372 26 31 255

1 1 4.00E-26

AGAP001467-PA AGAP001467-PA 112 132 1168 53 11 1041

1 1 4.00E-42

AGAP003687-PA AGAP003687-PA 164 118 900 67 13 783

1 1 1.00E-48

AGAP001484-PA AGAP001484-PA 186 116 412 77 28 297

7 1 4.00E-28

AGAP004203-PB AGAP004203-PB 118 109 2034 47 5 1925

1 1 2.00E-58

AGAP008516-PA AGAP008516-PA 218 115 519 89 22 405

1 1 1.80E-02

AGAP002737-PA AGAP002737-PA 33.1 106 6668 25 2 894

1 1 1.00E-56

AGAP011242-PA AGAP011242-PA 213 145 897 73 16 753

1 1 7.00E-73

AGAP010866-PA AGAP010866-PA 268 179 252 72 71 71

1 1 2.00E-48

AGAP002935-PA AGAP002935-PA 186 113 287 84 39 175

1 1 8.00E-32

AGAP009195-PA AGAP009195-PA 130 110 224 54 49 111

1 1 3.00E-39

AGAP003356-PA AGAP003356-PA 157 205 385 46 53 190

2 1 5.40E-01

AGAP001363-PA AGAP001363-PA 28.1 69 620 28 11 194

1 1 3.00E-51

AGAP011315-PA AGAP011315-PA 194 109 537 82 20 429

1 1 1.00E-45

AGAP012271-PA AGAP012271-PA 176 109 333 72 33 225

1 1 1.00E-56

AGAP003135-PA AGAP003135-PA 213 107 176 98 61 70

1 1 4.00E-59

AGAP012515-PA AGAP012515-PA 221 107 107 91 100 1

1 1 1.00E-49

AGAP009271-PA AGAP009271-PA 189 107 229 84 47 123

1 1 3.00E-43

AGAP006946-PA AGAP006946-PA 168 107 138 73 78 32

1 1 6.00E-56

AGAP011896-PA AGAP011896-PA 210 106 124 95 85 19

1 1 4.00E-55

AGAP007619-PA AGAP007619-PA 207 105 484 94 22 376

1 1 2.00E-41

AGAP012186-PA AGAP012186-PA 162 107 412 71 26 306

40 1 1.00E-42

AGAP011706-PA AGAP011706-PA 166 108 151 74 72 44

7 1 2.10E+00

AGAP004373-PA AGAP004373-PA 26.2 27 271 40 10 64

1 1 7.00E-59

AGAP001229-PA AGAP001229-PA 220 105 111 98 95 7

1 1 3.00E-50

AGAP002754-PA AGAP002754-PA 191 104 186 86 56 84

1 1 2.00E-50

AGAP009602-PA AGAP009602-PA 192 104 165 83 63 62

120 7 7.00E-09

AGAP007180-PA AGAP007180-PA 57 171 2328 28 7 120

1 1 5.00E-53

AGAP011424-PA AGAP011424-PA 201 103 148 97 70 46

1 1 4.00E-50

AGAP009508-PA AGAP009508-PA 191 103 192 94 54 90

3 2 5.00E-22

AGAP012008-PA AGAP012008-PA 97.8 106 304 54 35 199

1 1 6.00E-31

AGAP002630-PA AGAP002630-PA 127 61 89 85 69 29

4 1 1.00E-26

AGAP005620-PA AGAP005620-PA 113 71 110 73 65 40

1 3 2.00E-31

AGAP006063-PA AGAP006063-PA 129 122 584 58 21 395

37 1 2.60E+00

AGAP003817-PA AGAP003817-PA 25.8 31 832 38 4 131

Clustered Clustered Clustered Clustered

at 30%- at 40%- at 50%- at 60%-

Sim- on Sim- on Sim- on Sim- on

First Number Clustered 50% of 50% of 50% of 50% of

residue of of by length - - length - - length - - length - -

sequence segments psiblast # seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs Cluster#

1 4 17 2 20 2 16 2 16 2 15

1 1 29 2 31 2 110 1 111 1 117

1 1 83 1 84 1 84 1 85 1 91

1 1 26 2 29 2 170 1 173 1 180

1 1 145 1 146 1 156 1 158 1 165

2 1 93 1 94 1 94 1 95 1 101

1 1 148 1 152 1 162 1 164 1 171

1 1 165 1 170 1 183 1 186 1 193

17 2 178 1 187 1 200 1 205 1 213

1 1 10 2 13 2 10 2 10 2 10

1 1 141 1 142 1 152 1 154 1 161

1 1 36 2 38 2 30 2 219 1 227

1 6 33 2 151 1 161 1 163 1 170

1 1 28 2 141 1 151 1 153 1 160

1 1 147 1 148 1 158 1 160 1 167

2 1 105 1 107 1 109 1 110 1 116

19 1 169 1 174 1 187 1 190 1 197

26 1 81 1 82 1 82 1 83 1 89

1 1 183 1 192 1 205 1 210 1 218

4 1 22 2 25 2 18 2 18 2 17

1 1 31 2 35 2 139 1 140 1 147

2 2 18 2 131 1 136 1 137 1 144

3 1 77 1 77 1 77 1 78 1 84

5 1 107 1 109 1 112 1 113 1 119

1 3 130 1 130 1 135 1 136 1 143

6 1 29 2 31 2 148 1 150 1 157

1 1 127 1 127 1 132 1 133 1 140

12 3 156 1 161 1 174 1 177 1 184

3 1 5 7 6 3 44 1 44 1 48

2 2 89 1 90 1 90 1 91 1 97

1 1 160 1 165 1 178 1 181 1 188

5 4 17 2 20 2 16 2 16 2 15

1 1 114 1 115 1 119 1 120 1 126

1 1 114 1 115 1 119 1 120 1 126

2 1 51 1 51 1 47 1 47 1 53

1 1 151 1 155 1 165 1 167 1 174

1 1 177 1 186 1 199 1 204 1 212

3 1 152 1 157 1 168 1 170 1 177

1 1 159 1 164 1 177 1 180 1 187

1 2 155 1 160 1 173 1 176 1 183

1 1 36 2 38 2 30 2 196 1 204

1 1 8 2 10 2 8 2 8 2 37

2 1 20 2 32 2 209 1 215 1 223

1 1 91 1 92 1 92 1 93 1 99

1 1 24 2 27 2 20 2 19 2 18

1 1 110 1 32 2 115 1 116 1 122

1 1 173 1 180 1 193 1 197 1 205

1 1 97 1 98 1 98 1 99 1 105

1 1 175 1 183 1 196 1 201 1 209

5 1 74 1 74 1 74 1 75 1 81

23 1 45 1 46 1 38 1 38 1 40

1 1 185 1 194 1 207 1 212 1 220

1 1 10 2 13 2 10 2 10 2 10

1 1 40 2 41 2 33 2 31 2 29

1 1 143 1 144 1 154 1 156 1 163

1 1 157 1 162 1 175 1 178 1 185

38 1 71 1 71 1 71 1 72 1 78

1 1 119 1 119 1 124 1 125 1 131

1 9 170 1 175 1 188 1 191 1 198

2 1 98 1 100 1 100 1 101 1 107

1 4 67 1 67 1 67 1 67 1 73

1 1 190 1 199 1 213 1 220 1 228

1 2 70 1 70 1 70 1 70 1 76

1 7 59 1 60 1 57 1 57 1 63

1 3 75 1 75 1 75 1 76 1 82

1 2 122 1 122 1 127 1 128 1 134

4 1 44 1 45 1 37 1 37 1 39

1 1 174 1 181 1 194 1 199 1 207

1 2 112 1 113 1 117 1 118 1 124

1 1 26 2 29 2 106 1 107 1 113

62 1 39 2 40 2 32 2 29 2 28

1 1 120 1 120 1 125 1 126 1 132

2 1 132 1 133 1 141 1 142 1 149

1 1 100 1 102 1 102 1 103 1 109

1 5 63 1 63 1 61 1 61 1 67

1 1 31 2 35 2 223 1 231 1 239

21 1 199 1 208 1 224 1 232 1 240

1 1 158 1 163 1 176 1 179 1 186

1 1 85 1 86 1 86 1 87 1 93

2 1 171 1 176 1 189 1 192 1 199

1 1 35 2 37 2 28 2 26 2 25

2 1 38 2 182 1 195 1 200 1 208

16 1 184 1 193 1 206 1 211 1 219

1 1 21 2 24 2 17 2 17 2 16

2 1 202 1 212 1 228 1 236 1 244

4 1 198 1 207 1 222 1 230 1 238

1 1 139 1 139 1 149 1 151 1 158

1 1 37 2 39 2 31 2 28 2 27

14 1 73 1 73 1 73 1 74 1 80

1 1 40 2 41 2 33 2 31 2 29

1 1 197 1 206 1 221 1 229 1 237

1 1 87 1 88 1 88 1 89 1 95

1 1 30 2 34 2 25 2 24 2 22

9 1 64 1 64 1 62 1 62 1 68

38 1 117 1 117 1 122 1 123 1 129

34 1 133 1 134 1 142 1 143 1 150

3 1 146 1 147 1 157 1 159 1 166

34 3 57 1 58 1 54 1 54 1 60

1 1 9 2 11 2 9 2 9 2 9

1 1 103 1 104 1 105 1 106 1 112

1 2 90 1 91 1 91 1 92 1 98

1 1 181 1 190 1 203 1 208 1 216

11 1 58 1 59 1 56 1 56 1 62

1 1 38 2 210 1 226 1 234 1 242

1 1 11 2 14 2 11 2 11 2 11

1 2 14 2 17 2 13 2 13 2 13

1 1 168 1 173 1 186 1 189 1 196

1 1 116 1 116 1 121 1 122 1 128

1 1 113 1 114 1 118 1 119 1 125

1 1 76 1 76 1 76 1 77 1 83

1 1 19 2 22 2 137 1 138 1 145

1 1 95 1 96 1 96 1 97 1 103

1 1 111 1 112 1 116 1 117 1 123

1 1 55 1 56 1 52 1 52 1 58

1 1 163 1 168 1 181 1 184 1 191

1 1 108 1 110 1 113 1 114 1 120

2 3 15 2 18 2 14 2 14 2 14

1 1 19 2 22 2 64 1 64 1 70

1 1 201 1 211 1 227 1 235 1 243

1 1 42 1 43 1 35 1 35 1 33

1 1 8 2 10 2 8 2 8 2 36

1 1 154 1 159 1 171 1 174 1 181

1 1 137 1 21 2 146 1 147 1 154

1 3 140 1 140 1 150 1 152 1 159

1 1 203 1 213 1 229 1 237 1 247

1 1 28 2 106 1 108 1 109 1 115

1 1 109 1 111 1 114 1 115 1 121

1 3 48 1 48 1 42 1 42 1 46

1 3 131 1 132 1 140 1 141 1 148

1 1 50 1 50 1 46 1 46 1 51

4 1 196 1 205 1 219 1 226 1 234

1 1 80 1 81 1 81 1 82 1 88

12 1 60 1 61 1 58 1 58 1 64

2 1 142 1 143 1 153 1 155 1 162

1 1 124 1 124 1 129 1 130 1 136

1 1 82 1 83 1 83 1 84 1 90

1 1 186 1 195 1 208 1 214 1 222

1 1 84 1 85 1 85 1 86 1 92

7 1 33 2 150 1 160 1 162 1 169

1 1 125 1 125 1 130 1 131 1 137

7 1 115 1 23 2 120 1 121 1 127

1 1 92 1 93 1 93 1 94 1 100

1 1 138 1 138 1 147 1 149 1 156

1 1 144 1 145 1 155 1 157 1 164

1 1 164 1 169 1 182 1 185 1 192

1 1 72 1 72 1 72 1 73 1 79

9 1 182 1 191 1 204 1 209 1 217

1 1 128 1 128 1 133 1 134 1 141

1 1 180 1 189 1 202 1 207 1 215

1 1 32 2 149 1 159 1 161 1 168

1 1 96 1 97 1 97 1 98 1 104

1 1 167 1 172 1 185 1 188 1 195

1 1 86 1 87 1 87 1 88 1 94

1 1 61 1 62 1 59 1 59 1 65

1 1 150 1 154 1 164 1 166 1 173

1 1 106 1 108 1 111 1 112 1 118

1 1 136 1 137 1 145 1 146 1 153

53 1 149 1 153 1 163 1 165 1 172

1 1 166 1 171 1 184 1 187 1 194

1 1 172 1 178 1 191 1 194 1 202

1 1 62 1 21 2 60 1 60 1 66

120 10 79 1 79 1 79 1 80 1 86

1 1 20 2 23 2 65 1 65 1 71

1 1 179 1 188 1 201 1 206 1 214

6 1 188 1 197 1 211 1 217 1 225

42 1 68 1 68 1 68 1 68 1 74

32 1 104 1 105 1 107 1 108 1 114

1 2 15 2 18 2 14 2 14 2 14

6 1 191 1 200 1 214 1 221 1 229

Clustered Clustered Clustered Clustered

at 70%- at 80%- at 90%- at 95%-

Sim- on Sim- on Sim- on Sim- on

50% of 50% of 50% of 50% of

length - - length - - length - - length - -

# seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs Cluster# # seqs

2 62 1 61 1 61 1 59 1

1 120 1 120 1 122 1 123 1

1 94 1 93 1 94 1 95 1

1 184 1 184 1 190 1 194 1

1 169 1 169 1 174 1 178 1

1 104 1 104 1 105 1 106 1

1 175 1 175 1 181 1 185 1

1 197 1 198 1 206 1 210 1

1 217 1 218 1 227 1 233 1

2 39 1 38 1 34 1 31 1

1 165 1 165 1 170 1 174 1

1 231 1 232 1 241 1 247 1

1 174 1 174 1 180 1 184 1

1 164 1 164 1 169 1 173 1

1 171 1 171 1 177 1 181 1

1 119 1 119 1 121 1 122 1

1 201 1 202 1 210 1 214 1

1 92 1 91 1 92 1 93 1

1 222 1 223 1 232 1 238 1

2 13 2 13 2 11 2 9 2

1 150 1 150 1 155 1 159 1

1 147 1 147 1 151 1 154 1

1 87 1 86 1 87 1 87 1

1 122 1 122 1 124 1 125 1

1 146 1 146 1 150 1 153 1

1 161 1 161 1 166 1 170 1

1 143 1 143 1 146 1 149 1

1 188 1 188 1 194 1 198 1

1 47 1 46 1 44 1 42 1

1 100 1 100 1 101 1 102 1

1 192 1 192 1 198 1 202 1

2 61 1 60 1 60 1 58 1

1 129 1 129 1 132 1 134 1

1 129 1 129 1 132 1 134 1

1 54 1 53 1 52 1 50 1

1 178 1 178 1 184 1 188 1

1 216 1 217 1 226 1 232 1

1 181 1 181 1 187 1 191 1

1 191 1 191 1 197 1 201 1

1 187 1 187 1 193 1 197 1

1 208 1 209 1 217 1 222 1

1 32 1 31 1 27 1 24 1

1 227 1 228 1 237 1 243 1

1 102 1 102 1 103 1 104 1

2 14 2 14 2 12 2 11 2

1 125 1 125 1 128 1 130 1

1 209 1 210 1 218 1 223 1

1 108 1 108 1 109 1 110 1

1 213 1 214 1 222 1 228 1

1 84 1 83 1 84 1 84 1

1 35 1 34 1 30 1 27 1

1 224 1 225 1 234 1 240 1

2 38 1 37 1 33 1 30 1

2 24 2 255 1 266 1 273 1

1 167 1 167 1 172 1 176 1

1 189 1 189 1 195 1 199 1

1 81 1 80 1 81 1 81 1

1 134 1 134 1 137 1 139 1

1 202 1 203 1 211 1 215 1

1 110 1 110 1 111 1 112 1

1 76 1 75 1 76 1 76 1

1 232 1 233 1 242 1 248 1

1 79 1 78 1 79 1 79 1

1 66 1 65 1 65 1 63 1

1 85 1 84 1 85 1 85 1

1 137 1 137 1 140 1 142 1

1 34 1 33 1 29 1 26 1

1 211 1 212 1 220 1 225 1

1 127 1 127 1 130 1 132 1

1 116 1 116 1 117 1 118 1

2 23 2 23 2 246 1 252 1

1 135 1 135 1 138 1 140 1

1 152 1 152 1 157 1 161 1

1 112 1 112 1 113 1 114 1

1 70 1 69 1 70 1 68 1

1 245 1 246 1 257 1 264 1

1 246 1 247 1 258 1 265 1

1 190 1 190 1 196 1 200 1

1 96 1 95 1 96 1 97 1

1 203 1 204 1 212 1 216 1

2 20 2 20 2 205 1 209 1

1 212 1 213 1 221 1 227 1

1 223 1 224 1 233 1 239 1

2 12 2 12 2 10 2 75 1

1 250 1 251 1 262 1 269 1

1 244 1 245 1 256 1 263 1

1 162 1 162 1 167 1 171 1

2 22 2 22 2 19 2 15 2

1 83 1 82 1 83 1 83 1

2 24 2 254 1 265 1 272 1

1 243 1 244 1 255 1 262 1

1 98 1 97 1 98 1 99 1

2 18 2 18 2 153 1 157 1

1 71 1 70 1 71 1 69 1

1 132 1 132 1 135 1 137 1

1 153 1 153 1 158 1 162 1

1 170 1 170 1 176 1 180 1

1 63 1 62 1 62 1 60 1

2 9 2 9 2 8 2 7 2

1 115 1 115 1 116 1 117 1

1 101 1 101 1 102 1 103 1

1 220 1 221 1 230 1 236 1

1 65 1 64 1 64 1 62 1

1 248 1 249 1 260 1 267 1

2 10 2 10 2 37 1 34 1

2 43 1 42 1 40 1 37 1

1 200 1 201 1 209 1 213 1

1 131 1 131 1 134 1 136 1

1 128 1 128 1 131 1 133 1

1 86 1 85 1 86 1 86 1

1 148 1 148 1 152 1 155 1

1 106 1 106 1 107 1 108 1

1 126 1 126 1 129 1 131 1

1 59 1 58 1 57 1 55 1

1 195 1 196 1 203 1 207 1

1 123 1 123 1 125 1 127 1

2 50 1 49 1 48 1 46 1

1 73 1 72 1 73 1 72 1

1 249 1 250 1 261 1 268 1

1 28 1 27 1 23 1 19 1

1 31 1 30 1 26 1 23 1

1 185 1 185 1 191 1 195 1

1 158 1 158 1 163 1 167 1

1 163 1 163 1 168 1 172 1

1 253 1 256 1 267 1 274 1

1 118 1 118 1 120 1 121 1

1 124 1 124 1 127 1 129 1

1 45 1 44 1 42 1 39 1

1 151 1 151 1 156 1 160 1

1 52 1 51 1 50 1 48 1

1 240 1 241 1 252 1 259 1

1 91 1 90 1 91 1 92 1

1 67 1 66 1 67 1 65 1

1 166 1 166 1 171 1 175 1

1 139 1 139 1 142 1 145 1

1 93 1 92 1 93 1 94 1

1 226 1 227 1 236 1 242 1

1 95 1 94 1 95 1 96 1

1 173 1 173 1 179 1 183 1

1 140 1 140 1 143 1 146 1

1 130 1 130 1 133 1 135 1

1 103 1 103 1 104 1 105 1

1 160 1 160 1 165 1 169 1

1 168 1 168 1 173 1 177 1

1 196 1 197 1 204 1 208 1

1 82 1 81 1 82 1 82 1

1 221 1 222 1 231 1 237 1

1 144 1 144 1 148 1 151 1

1 219 1 220 1 229 1 235 1

1 172 1 172 1 178 1 182 1

1 107 1 107 1 108 1 109 1

1 199 1 200 1 208 1 212 1

1 97 1 96 1 97 1 98 1

1 68 1 67 1 68 1 66 1

1 177 1 177 1 183 1 187 1

1 121 1 121 1 123 1 124 1

1 157 1 157 1 162 1 166 1

1 176 1 176 1 182 1 186 1

1 198 1 199 1 207 1 211 1

1 206 1 207 1 215 1 219 1

1 69 1 68 1 69 1 67 1

1 89 1 88 1 89 1 89 1

1 74 1 73 1 74 1 73 1

1 218 1 219 1 228 1 234 1

1 229 1 230 1 239 1 245 1

1 77 1 76 1 77 1 77 1

1 117 1 117 1 118 1 119 1

2 49 1 48 1 47 1 45 1

1 234 1 235 1 244 1 250 1

Codon

volatility Codon

housekeep volatility

ing secreted P

0.821333 0.814077

0.799173 0.811267 6.91E-08

0.794043 0.806313

0.794033 0.803515

0.793626 0.802605

0.79343 0.802355

0.7918 0.795632

0.789917 0.795336

0.785591 0.79462

0.784719 0.793813

0.784534 0.79354

0.784056 0.793401

0.783914 0.793281

0.783086 0.793063

0.782921 0.792969

0.782019 0.792928

0.781317 0.792687

0.781269 0.792135

0.780849 0.792095

0.780061 0.792092

0.779699 0.791449

0.779406 0.79103

0.779195 0.790201

0.779184 0.789294

0.779099 0.789233

0.777704 0.788473

0.776878 0.787827

0.776669 0.786902

0.775668 0.786272

0.775349 0.785411

0.774911 0.783034

0.774232 0.782929

0.774008 0.781781

0.773915 0.780715

0.773859 0.780197

0.773513 0.779899

0.773337 0.77867

0.773268 0.777605

0.773139 0.777586

0.773137 0.776897

0.773118 0.774839

0.773068 0.774365

0.773032 0.773192

0.772925 0.770205

0.772523 0.768912

0.771778 0.768351

0.77162 0.767911

0.771588 0.767709

0.771396 0.766805

0.771382 0.766476

0.770933 0.765121

0.770413 0.764569

0.76996 0.763462

0.769782 0.763416

0.769195 0.762879

0.769104 0.762762

0.769012 0.762758

0.769012 0.76264

0.768758 0.762345

0.768303 0.762306

0.768256 0.761525

0.768211 0.761204

0.768074 0.760736

0.767954 0.76021

0.767541 0.759913

0.7675 0.75607

0.766966 0.754947

0.766954 0.754492

0.766608 0.753638

0.766422 0.753286

0.766078 0.751386

0.765987 0.749598

0.765763 0.749407

0.765406 0.748418

0.765316 0.747452

0.765027 0.74741

0.764976 0.745187

0.76484 0.74491

0.764829 0.728387

0.76472 0.722493

0.764356

0.764224

0.764178

0.764137

0.763869

0.763566

0.762974

0.762937

0.762707

0.762588

0.762204

0.762033

0.761835

0.761832

0.761588

0.761003

0.760877

0.760762

0.760691

0.760503

0.760116

0.759902

0.759893

0.759788

0.759774

0.759591

0.75942

0.758979

0.758667

0.758442

0.75832

0.758319

0.758308

0.758225

0.758179

0.758139

0.758056

0.7579

0.757797

0.757738

0.757373

0.757198

0.757192

0.757087

0.75699

0.756809

0.756665

0.756632

0.756622

0.756298

0.756102

0.756093

0.75602

0.75581

0.755333

0.754786

0.754691

0.754458

0.754443

0.754271

0.754194

0.754151

0.754074

0.753659

0.753564

0.753491

0.753276

0.753094

0.75265

0.752456

0.751366

0.751221

0.751195

0.751009

0.750922

0.750907

0.750449

0.750346

0.75033

0.750226

0.750173

0.750141

0.749904

0.749866

0.749686

0.749669

0.749517

0.74883

0.748649

0.748068

0.747807

0.74777

0.747664

0.747158

0.746686

0.746628

0.745944

0.745904

0.745692

0.745619

0.745586

0.745155

0.744716

0.744674

0.744103

0.743434

0.74278

0.741466

0.741331

0.74091

0.740387

0.740365

0.740114

0.739545

0.739234

0.738134

0.737738

0.737459

0.736435

0.735108

0.733882

0.733433

0.725557

0.705026

0.703655







0.760984 0.774685

0.015204 0.019079

205 80

0.001062 0.002133



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