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fMRI Data Analysis Tutorial: for Afni.

# In this tutorial, the sample E file is E17239, the P file P01024,

# the subject name Pl09. Unix prompts are highlighted in bold.

# Comments are preceded by the # sign.





# =============================================

# Pre-analysis stuff: for Windows.

# =============================================



 Open X-server, in my case X-Win32.

 Open your telnet program, in my case Tera Term Pro.

 Telnet into 128.196.98.34

 login: ryanlab

 password: *******



# Now you should be in sol4, where I analyze data.

# First thing‟s first. Get out of the dumb C shell and into the friendly TC shell.

# And then set up the X-Forwarding so you can see afni.



 sol4% tcsh

 /home/ryanlab> display

 /home/ryanlab> host



# =============================================

# Pre-analysis stuff: for Linux.

# =============================================



# secure shell to Sol4.



 /home/mhsu> ssh –l ryanlab 128.196.98.34

 password: *******



# =============================================

# Pre-analysis stuff: On your own computer.

# =============================================



Nothing. You should know what to do. :)



# ============================================

# Section 1: Making directories to store data

# ============================================



 /home/ryanlab> cd /data/jacobs

 /data/jacobs/> mkdir Pl09

 /data/jacobs/> cd Pl09

 /data/jacobs/Pl09> mkdir run1

 /data/jacobs/Pl09> mkdir Anatomy



# =================================================

# Section 2: Data Transfer

# =================================================



# Now we get the data, which is behind the UMC firewall, so we have to go through a

# proxy, mrisun.



 /data/jacobs/Pl09> telnet mrisun.radiology.arizona.edu

 login: Guest

 Password: anonymous









1

# Make a directory to store your files.



 mrisun% cd /data/ryanlab

 mrisun% mkdir e17239

 mrisun% cd e17239



# Now ftp to Sol3, where the files are stored, and get them.



 mrisun% ftp 198.60.162.30

 ftp> cd /data/ryanlab

 ftp> ls

 ftp> cd e17239

 ftp> prompt off

 ftp> bin

 ftp> mget E* P*

 ftp> quit

 mrisun% ls –trl |more



# When you have all files in mrisun, go to Sol4, put the P file into run1,

# E files into Anatomy, and delete the files from mrisun.



 mrisun% ftp 128.196.98.34

 login: ryanlab

 password: *******

 ftp> cd /data/jacobs/Pl09/run1

 ftp> prompt off

 ftp> bin

 ftp> mput P01024

 ftp> cd ../Anatomy

 ftp> mput E*

 ftp> ls –l |more

 ftp> quit

 mrisun% rm E*

 mrisun% rm P*

 mrisun% ls

 mrisun% exit



#Now you should be back in Sol4 and ready for the next stage.





# ====================================================

# Section 3: Reconstructing the Functional Images

# ====================================================



 /data/jacobs/Pl09> cd run1/

 /data/jacobs/Pl09> ls

 /data/jacobs/Pl09> /usr/bin/recon/spiral/grecons5x P01024; rm B0*

 /data/jacobs/Pl09> /usr/bin/spiral_rename P01024



# Now push back the directory stacks.



 /data/jacobs/Pl09> pushd /data/jacobs/Pl09/run1

 /data/jacobs/Pl09> popd



# ====================================================

# Section 3a: Anatomical bricks (Can be done at same time as reconstruction)

# ====================================================



# Sorry, but you need to do this for each series. Maybe one day it‟ll change.



 /data/jacobs/Pl09> /data/jacobs/scripts/rename_anat.scp Anatomy/E17239S3







2

 /data/jacobs/Pl09> to3d –anat –prefix brain seqplus „Anatomy/E17239S3*‟



# Now you‟re in the to3d program will open a window on the desktop.



 Click “View Images”



# The following may change, as sometimes data will be acquired in a strange way,

# so keep an eye on the alignment.



 In “Orientation”, change values to:

 Right to Left

 Superior to Inferior

 Anterior to Posterior

 Click “Irregular”

 Change value of “z voxel” from 3.75 to 6.

 Click “save”

 Click “quit”



# ====================================================

# Section 4: Constructing Functional bricks

# ====================================================



# 177 = number of reps; 23 = number of slices; 3000 = TR.



 /data/jacobs/Pl09> to3d –epan –prefix run1 –time:tz 177 23 3000 seqplus

„run1/P01024.*‟



# Now you‟re in the to3d program will open a window on the desktop.



 Click “View Images”



# The following may change, as sometimes data will be acquired in a strange way,

# so keep an eye on the alignment.



 In “Orientation”, change values to:

 Right to Left

 Superior to Inferior

 Anterior to Posterior

 Click “Irregular”

 Change value of “z voxel” from 3.75 to 6.

 Click “save”

 Click “quit”



# ====================================================

# Section 5: Reregistering images.

# ====================================================



 /data/jacobs/Pl09> 3dvolreg –verbose –Fourier –prefix run1_reg –base 3 –dfile

run1_reg.log run1+orig



# If you are reregistering a run to another run (e.g., run2 to run1), use this:



 /data/jacobs/Pl09> 3dvolreg –verbose –Fourier –prefix run2_reg –base „run1_reg –

base „run1_reg+orig[3]‟ –dfile run2_reg.log run2+orig





# ==============================================================

# Section 6: Normalizing images (unnecessary if have only 1 run.

# ==============================================================

 /data/jacobs/Pl09> from3d –input run1_reg+orig –prefix ./run1/run1_reg



# Creative bshort files: fgs always = 1; nas = # anat slices; nfs = # func slices.







3

 /data/jacobs/Pl09> afnireg3bshort –I ./run1/run1_reg –fgs 1 –nas 23 –nfs 177



# Normalizing images, bshorts -> bfloats: nslices = # anat slices.



 /data/jacobs/Pl09> inorm –I ./run1/run1_reg –o ./run1/run1_reg_norm –nslices 23



# Making bfloats into afni bricks: need to change 3Df:0:0:64:64:??? to match # of

# functional images.



 /data/jacobs/Pl09> to3d –epan –prefix run1_norm –time:tz 177 23 3000 seqplus

3Df:0:0:64:64:177:run1_reg_norm\*.bfloat





# ===================================================================

# All done with registration and normalization. Ready to analayze!!!

# ===================================================================









4



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