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STARS NOTES

S C I E N C E T E A C H E R A C C E S S T O R E S O U RC E S AT S O U T H W E S T E R N STARS Notes









Fall 2009 STARS Events

•••••••••••••••••••••••••••••••••••••••••••••••••• January 2010

Volume XV, Number 1





on Lung Cancer and Leukemia: Genomic Approaches to

A ll STARS activities and events are offered free of charge

to teachers in the state of Texas.

Assessing Radiation Risks. The afternoon session began with

a presentation on Radiation Effects on the Brain by Amelia

Eisch., Ph.D., Assistant Professor of Psychiatry. Benjamin

STARS SYMPOSIA consist of a series of lectures given by Levine, M.D., Professor of Internal Medicine spoke about

scientists and physicians currently doing research at Radiation Effects on the Cardiovascular System followed by a

UT Southwestern Medical Center and affiliated institutions. presentation from Oliver Delgado, graduate student in

The science symposia and inservice sessions are excellent cancer biology on Using Mice to Assess Radiation Effects on

resources for teachers to learn about cutting-edge research in Cancer Initiation and Progression. Jerry Shay, Ph.D., Professor

the biomedical sciences, to discover new classroom activities, of Cell Biology and the speaker organizer, ended the day

and to obtain professional development credit at the same with a look at Countermeasures to Protect Against Radiation

time. If you wish to attend any event, please pre-register by Damage.

calling 214-648-9505 or visiting our online registration page

at https://ais.swmed.edu/starsevent/



Mini-Symposium: Nanomedicine for Cancer Imaging

and Therapy– Sept. 14, 2009

Working with nanotechnology, scientists are creating new

tools, products, and technologies to diagnose and treat

diseases like cancer. Our first talk by David A. Boothman,

Ph.D., Professor, Simmons Comprehensive Cancer Center,

was on B-Lapachone: A ‘kiss of death’ therapy for cancer. Jinming

Mini-Symposium: Adaptation: From Dinosaurs to DNA (In

Gao, Ph.D., Associate Professor, Simmons Comprehensive

Cancer Center, gave a presentation on Nanomedicine for Collaboration with The Museum of Nature & Science) – Nov. 2, 2009

This mini-symposium featured two talks, one on Charles

Cancer Imaging & Therapy. Teachers really enjoyed getting a

Darwin/animal adaptation and another one on molecular

presentation on this emerging field of research. adaptation, and a hands-on DNA activity for middle school

students. Anthony Fiorillo, Ph.D., Curator of Earth Sciences,

Museum of Nature & Science, gave a talk on “Charles Darwin,

Special Science Symposium: Space Travel, Radiation,

Toothed Birds, and Denali National Park, Alaska”. He focused on

and Health – Oct. 3, 2009 Charles Darwin, his intrigue with tooth birds, and how Alaska

More than 200 Dallas area teachers/students, UTSW facul- served as a gateway for avian faunal exchange between Asia &

ty/staff/students, and other university guests participated in North America as early as the Late Cretaceous (lots of fossil

our special symposium on Space Travel, Radiation, and records). After the break, Marsha Chinal, Instructor, Museum

of Nature & Science, took 24 middle/high school students for

Health. This event was sponsored by STARS and the Harold a break-out session on DNA extraction using strawberries, fin-

C. Simmons Comprehensive Cancer Center. Opening gerprinting, and handwriting analysis. Richard K. Bruick,

remarks were made by Dr. Daniel K. Podosky, president of Ph.D., Associate Professor, Department of Biochemistry, fin-

UT Southwestern, followed by U.S. Congressman Ralph M. ished the symposium session with a lecture on Molecular

Hall, the ranking member of the House Science and Adaptation: How Mammalian Cells Sense and Respond to Their

Environment. He focused on how cells have factors that can

WHAT’S INSIDE

Technology Committee. The first presenter was Richard

sense environmental/metabolic signals and how cells have

Scheuring, D.O., M.S., F.A.A.F.P., Flight Surgeon,

mechanisms to adapt to their environment. Understanding Exploring Post.................................2

Constellation Medical Operation, Johnson Space Center these sensing and signaling pathways may allow us new Virtual Instruments ........................2

and his topic was on Introduction to Space Medicine. avenues to treat diseases.

Spring ‘10 Calendar .......................3

STARS Science Suitcases .............3

Dr. Scheuring was followed by a talk on What Is NASA Doing

to Assess and Reduce Risk, by Francis Cucinotta, Ph.D., Chief

Scientist for NASA’s Space Radiation Program. Andreg Roig, Staff & Programs...........................4

M.D., assistant instructor of internal medicine, gave a talk

on Introduction to Cancer and How I Became Interested in Space

Science followed by a presentation from David Chen, Ph.D.,

professor of radiation oncology, on Radiation DNA Damage

and Repair. The morning session concluded with a talk by

1

Michael Story, Ph.D., associate professor of radiation oncology,

Continued on Page 3

Virtual Instruments – Valuable Teaching Tools

A s a teacher are you frustrated with a lack of scientific equipment? Are

half your microscopes broken or out for repair? Would you like to use

The Virtual Spectrophotometer is available now for your students. The

software comes with several solutions, or you can make your own

a spectrophotometer, but even a cheap one is way out of your budget? (instructions are included). Your students can determine the absorbance

of solutions (after blanking the instrument with air, water, or another

UT Southwestern is developing a suite of virtual instruments that could solvent) and calculate concentrations of solutes with Beer’s Law as long

be of great benefit to your teaching efforts. The first two of these are now as they adjust the virtual instrument to the correct wavelength and

“ready for prime time.” Others will be developed in the next few years. know the extinction coefficient. Have your students determine the

maximal wavelength. Some of the samples provided even change over

The Virtual Microscope (VI) simulates an actual binocular optical com- time as they are oxidized; students can observe this and plot the rate of

pound microscope. When the software is started up, your students oxidation.

observe a 3-D microscope. The parts of the microscope are labeled with

the click of a mouse. The virtual instruments come with a Teachers Manual and a QuickStart

Guide. The software runs on the PC or on Macintoshes that can run

In fact, the mouse is used to turn all knobs and push all buttons. Go Windows (all Macs produced in the last several years). Right now the

select a slide such as “normal kidney” and it appears on the stage. Turn software is available (at no charge to teachers) on a CD – simply request

the microscope light source on (with the mouse) and dial up the light one from the STARS office and on a website for download at

intensity. To the left of the microscope, on the screen, your students https://ais.swmed.edu/starslab. We are in the beginning stages of devel-

observe the view from the eyepieces. This view is used as they adjust the oping virtual gel boxes (for separation of proteins, DNA and RNA) as

stage to be directly over the light source, and they focus on the sample. well as a virtual thermocycler (for the polymerase chain reaction, or

What are those specks that come into focus? Must be dust on the slide. PCR). Samples generated by PCR from an included genome database

Finally, the image of the kidney appears, and is made clearer by turning can be subjected to electrophoresis in a gel box. Now, how cool is that!

the fine focus knob. Adjusting the condenser iris improves the contrast. Request your Virtual Instruments today!

Students can improve resolution by turning the objective ring to use the

10x or 40x objective. Have your students find a kidney glomerulus. The Virtual Instruments are a part of the Howard Hughes Medical

With the attached camera the students can save or print a micrograph Institute-provided grant to UT Southwestern with additional funding by

of what they see in the scope and send it to the teacher for comment. The Peter O’Donnell Foundation and the UTSW medical school. The

software was written by Dr. Ken Meissner at Texas A&M, with consulta-

At present several human tissues, both normal and in a disease state, can tion by staff at UTSW and teachers at Advanced Placement Strategies

be selected for viewing. Show your students what smoking can do to and Laying The Foundation. The LabView software engine was donat-

the lung, or drinking can do to the liver. Ask them to describe what they ed by National Instruments.

see – observation is a key part of science. We have just added mitosis

slides and lesson plans. These will be featured in our next in-service ses- Please register for the February in-service on the Virtual Instruments at

sion. https://ais.swmed.edu/starsevent/. STARS will demonstrate how to use it

in the classroom and provide lesson plans and labs that will go along

A spectrophotometer is essential in most labs at UT Southwestern and with the instrument.

is a great educational tool to teach students how chemicals or macro-

molecules can be identified or quantified. Unfortunately, spectropho-

tometers are expensive.









Science & Health Careers Exploring Post at UT Southwestern:

•••••••••••••••••••••••••••••••••••••••••••••••••••









Upcoming Meetings: The explorers meet monthly at

UT Southwestern Medical center in

6:00 PM – 7:30 PM room D1.200 from 6pm-7:30pm.

Interested students may attend for

Monday-Jan. 25th free and yearly membership is

Saturday-Feb. 20th $10.00.



Monday-March 29th Parents are always welcome!!

Monday-April 26th

Check out the website for more

I Learn about careers in science and medicine. Monday-May 24th information and pictures from past

I Meet and network with professionals in different areas meetings:

http://www.utsouthwestern.edu/stars

of medicine.

I Come and meet students from different Dallas schools

(click on Exploring POST)



that share a passion for health careers and science.

I Enjoy free snacks and engage in some fun hands-on activities and experiments.



The explorers meet monthly at UT Southwestern Medical center in room D1.200 from 6pm-7:30pm.

2 Interested students may attend for free and yearly membership is $10.00. Parents are always welcome!!

Spring 2010

STARS Summer Research Calendar of Events

for Teachers 2010 Jan. 11, 2010 Monday 5:30 pm - 8:00 pm

Mini-Symposium: Membrane Transport

Discover & Immerse Yourself in a Culture Lecture Hall, D1.502

Environment of Cutting-Edge Scientific Research Feb. 6, 2010 Saturday 9:00 am - 3:00 pm

Teacher Inservice: Virtual Instruments w/ Lesson Plans

E ach summer, the STARS Program at UT Southwestern

Medical Center offers opportunities for teachers to work one-

Meeting Room, D1.200

Limited Enrollment

on-one with faculty researchers on an investigative project in

Mar. 6, 2010 Saturday 9:00 am - 3:00 pm

a laboratory setting. The purpose of this program is to

Special Symposium:

provide teachers the opportunity to perform biomedical

research as a way to help bring new ideas to the classroom Women in Science and Medicine

and to rekindle their interest in science. Teachers will be Lecture Hall, D1.502

matched with a faculty mentor with similar interests and will Please invite your female students to attend with you.

work on a laboratory research project during the course of the April 5, 2010 Monday 5:30 pm- 8:00 pm

summer. As part of the program, participants will develop a

Mini-Symposium: Protein Degradation in

classroom activity related to their research experience,

Health & Disease

produce a poster, and give an oral presentation at the

conclusion of the summer session. The eight-week program Lecture Hall, D1.502

will begin on June 7th and end on July 30, 2010. A stipend Other Important Dates to Remember

will be paid to each teacher, plus monies for classroom Jan. 15, 2010 - Deadline for Science Fair Judge

supplies for their participation in the program. Teachers must Requests

complete an on-line application, essay, and letter of

recommendation from your principal. Please apply on-line at Friday, Feb. 5, 2010, at 4pm







STARS Science Suitcases: Enzyme

WWW.UTSOUTHWESTERN.EDU/STARS. Deadline for Summer Research Program

Applications







Instigator, Organelles Extravaganza

June 7, 2010 - Summer Research Program Begins







& Photosynthesis Suitcase

July 30, 2010 - Summer Research Program Ends

All events are held on the UT Southwestern South Campus.

For directions, call the STARS office or visit the STARS Web page.



Check It Out! TWO science suitcases, the Enzyme Instigator

& Organelle Extravaganza are now available for check out! They contain everything from lesson plans, curriculum

guides, and homework worksheets to videos, games, models, and wet labs needed to teach a concept. The

Photosynthesis Suitcase will be available soon for check out. It will contain teacher and student manuals, animation

DVD, a board game (Sugar Rush), and three hands-on labs. It was featured in our December in-service with great

excitement. Contact the STARS office for more details or to sign up!

STARSmail@UTSouthwestern.edu or 214-648-9505.









Fall 2009 STARS Events

••••••••••••••••••••••••







Continued from Page 1

Teacher In-service: Science Suitcases: Photosynthesis – Dec. 5, 2009

This in-service started with a presentation by Amanda J Wright, Ph.D,

Assistant Professor, Department of Biological Sciences, UNT, on

Controlling Division Plane Orientation in Plants. Dr. Wright talked about

her research on Zea mays (maize plants), subsidiary cells (only found

in monocot plants), and how the dcd1 mutant phenotype in these

plants lead to abnormal subsidiary cells that may affect stomata func-

tion. The morning session concluded with a preview on the

Evolution Suitcase by Corbyn Beach, Student Research Assistant,

Biomedical Communications. In the afternoon session, we featured

the third of our seven planned science suitcases on Photosynthesis.

Teachers are provided with everything that is needed to run the labs

and to teach the lessons. The creator of the Photosynthesis Suitcase,

Derek Wu, Student Research Assistant, Biomedical Communications,

came and gave an introduction and an overview of his work. The

teachers spent the rest of the day going over the activities, playing the 3

board game (Sugar Rush), and testing out the labs.

Missed it or Want to

STAFF PROGRAMS

See it Again?

Joel Goodman, Ph.D.

STARS Director SYMPOSIA

Professor of Pharmacology Basic Science Symposia

Jan and Bob Bullock Distinguished Mini-Symposia

Chair for Science Education If you missed a STARS Basic Science

John P. Perkins Distinguished OUTREACH Symposium / Mini-Symposium or want

Professorship in Biomedical Science Bureau of Science Fair Judges to share it with your students and/or

joel.goodman@utsouthwestern.edu Distance Learning Initiative

Research Assistance colleagues, you can order a FREE DVD

Stuart Ravnik, Ph.D. Science Ambassadors of the event(s). Just give us a call or

STARS Associate Director Student Mentoring email.

Assistant Director, Graduate School

stuart.ravnik@utsouthwestern.edu SUMMER RESEARCH

Lynn Tam Summer Research Program for Teachers

Education Program Coordinator Summer Research Program for Students

lynn.tam@utsouthwestern.edu

TOURS

Gwen Johnson UT Southwestern School of Health Professions

Education Assistant UT Southwestern Medical Center

gwen.johnson@utsouthwestern.edu Parkland Health & Hospital System of Dallas

Children’s Medical Center Dallas

Kristie Conner

Education Assistant INSERVICE SESSIONS

kristie.conner@utsouthwestern.edu Proteins & Enzymes

Protein Crystal Growth

5323 Harry Hines Blvd. Genetics

Dallas, Texas 75390-9137 PCR & Gel Electrophoresis

(214) 648-9505 Suturing Techniques

(800) 81-STARS

FAX: (214) 648-9508 SCIENCE TRIATHLON

UT Southwestern is an equal opportunity Supported by

institution. Core funding for the STARS Howard Hughes Medical Institute

program is provided by the state of Texas.

Visit our web site at

www.utsouthwestern.edu/stars







Nonprofit Org.



STARS U.S.POSTAGE

PAID

Dallas, Texas

Permit No. 1233

5323 Harry Hines Blvd.

Dallas, TX 75390-9137









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