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posted:
11/4/2011
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Displayed numeric precision



Mass precision 1

Retention time precision 1



Labeling

Label chromatogram peaks with Index

Unit disabled

Smoothing of chromatograms and mass spectra



Smoothing algorithm Savitzky Golay

Smoothing width (m/z) 0.2

Cycles 1

Replace original disabled

Use same color as original enabled

Disable original enabled





Baseline subtraction of mass spectra

Flatness (0-1): 0.8

Replace original disabled

Use same color as original enabled

Disable original enabled

General

XML compound export

Include detailed information disabled

Include peptide database query information enabled





Mascot compound export

Include peptide database query information enabled





Peptide Database Query

Global charge setting

Set global charge limitation: 2+ and 3+

Note: The global charge state setting applies to non-deconvoluted ions only.

This setting here will override any other setting in the Mascot search

parameter.





Export for 'MS/MS Search' and 'Peptide Mass Fingerprint' Mixed list (non-deconvoluted and deconvoluted)

Include S/N ratio and FWHM disabled

Normalize MS(n) data enabled



Export for 'MS/MS Search'

Prefer Full Scan spectrum deconvolution results to MaxRes results enabled

Export N most abundant non-deconvoluted ions of each MS(n) spectrum 50



Export for 'Peptide Mass Fingerprint'

Export N most abundant ions of each MS spectrum 2

deconvoluted and deconvoluted)

Chromatogram, MS(n)

Compound detection

S/N threshold 1

Area threshold Relative [%] 0.1

Intensity threshold Relative [%] 0.1

Skim ratio 0.1

Smoothing width 1



Mass spectrum calculation

Spectrum type (Line/Profile): Auto

Additional background subtraction:* (MS only) Peak start and end spectra

*) Note:'Constant' (Background mass spectrum) and 'Spectral' background subtraction is defined by the chromatogram trace definiti





AutoMS(n)

Compound detection



Intensity threshold, pos. 10000

Maximum number of compounds 250

Fragments qualified by Amino Acids disabled

Merge positive and negative compounds disabled



Retention time window for compound detection

Retention time window [min] 0.5



Mass spectrum calculation

Spectrum type (Line/Profile) Profile spectra only

Background subtraction (MS only) Peak start and end spectra



AutoMS(n) chromatogram traces

Create individual AutoMS(n) chromatogram traces enabled

Create additional detailed chromatogram traces disabled





Delete previously found compounds in selected range enabled

is defined by the chromatogram trace definition.









neg. 1000

Mass List Layout

Mass List

Peak Number (#)

Mass-to-Charge Ratio (m/z)

Intensity (I)

Full Width at Half Maximum (FWHM)

Signal-to-Noise Ratio (S/N)





Compound List Layout

Compound List

Peak Number (#)

Retention Time (RT)

Integration Type (Int. Type)

Peak Area (Area)

Peak Range (Range)

Selected peak finder algorithm:

Apex enabled

Centroid disabled



Apex

Peak width (FWHM) (m/z) 0.1

S/N threshold 1

Relative intensity threshold (base peak) 2%

Absolute intensity threshold 100



Exclusion Masses

Filter exclusion masses disabled



Interactive Mass List editing

Use peak finder to calculate peak position enabled

Proteins/large molecules disabled

Peptides/small molecules enabled





Peptides/Small Molecules



Adduct ions +H -H

Deconvolute

MS Full Scan ) enabled

MS MaxRes Scan

MS(n) enabled

Low mass 250 100 50 250 100 50

High mass 4000 3000 2000

Abundance cutoff [%] 10 2

Resolved-isotope deconvolution

Maximum charge 2 3 1

Allow precursor deconvolution from fragment spectra enabled



Note: License option for charge deconvolution of higher charge states not present.





General

Extend reconstructed mass envelope (profile spectra, only) disabled

Add before 0

Add after 0

Include shifted spectrum disabled

Include component details disabled

Retain residual disabled

Show component details and residual disabled



Clear previous results enabled

Create neutral spectrum (instead of singly charged spectrum) disabled

Exclusion mass ranges



No masses excluded



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