USAID/PAHO Project for the Prevention and Control of Antimalarial Resistance in the Amazon
Work Plan for the Period October 2001 through September 2002
Country Work Plan VENEZUELA
Intermediate Result 1 - Reliable and standardized malaria drug efficacy information available. Indicators: 1) Number of target countries that have selected an adequate
number of sentinel surveillance sites, including a reference laboratory, and initiated training activities. 2) Number of target countries where the WHO/PAHO protocol has been
adapted. 3) Number of target countries that initiated anti-malarial drug resistance studies based on the WHO/PAHO protocol.
Activities Tasks Staff , other human resources, Product Month/ Remarks
and other inputs Year
A1.1. Establish a 1. Participate in the first regional PAHO focal point, Project plan and common agenda March 02 Cost included in task A3.1
regional network for technical meeting for reaching Project country coordinator 2002 consensus whit other partners.
surveillance of drug consensus about project work
resistance and plan, and common agenda
monitoring of 2002.
2. Participate in intercountry PAHO focal point, Informed working groups March -02 Cost included in task A3.1
activities under
coordinating committee to: National project coordinator -Regional centers with potential to to
coordination of
Monitor progress in PAHO/WHO integrate the regional network for September
PAHO.
protocol adaptation. surveillance of drug resistance 2002
Obtain consensus regarding the identified.
resistance testing methods, and -Progress reports on protocol
in monitoring, evaluation and implementation
quality control indicators. -Management indicators and protocols
for quality control established.
A.1.2. Establish 1. Conformation of a National - National technical advisory * National technical advisory committee Dec - 01 In preliminary meetings, the
National sentinel Technical Advisory Committee committee integrated by operational following academic institutions
surveillance by the Ministry of Health (MSDS) representative of: * Coordinator designated, were:
networks with and national research centers. * Central level (PAHO, MSDS, * Agenda established, * C.A.I. C.E.T
quality control in IESPA, IVIC) * Antimalarial drug resistance * UCV (Tropical Medicine
each target country * Regional Service Director from surveillance network established Institute)
to assess the the states of Sucre, Amazonas and * IVIC ( Microbiology Center)
efficacy of Bolívar, and * MSDS (Epidemiological
antimalarial drugs. * National Research centers. Surveillance Department)
2. Identify and select five (5) National technical advisory Five sentinel sites selected in the Jan-Sep Three sentinels sites will be
sentinel sites in Atures y committee states of Amazonas (2), Bolivar (2) 2002 operated by personnel
Manapiare (municipalities of the and Sucre (1) contracted under AMI funds;
state of Amazonas); two sentinel sites will be run
Maripa y Tumeremo ( state of with personnel from
Bolívar) and Cajigal (state of governmental institutions
Sucre) according to (MSDS, National Commission
epidemiological parameters. of Scientific Research and
Technical and NGOs.
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3. Begin operations of sentinel Physicians (3) = 62.400 Microscopy '- Human resources will have been Jan-Sep The project will cover
sites technologist (3) = 23.400 contracted. 2002 personnel expenses for first
Nursing auxiliaries (3) = 19.500 (*) - Sentinel sites structured in year to guarantee its success.
accordance with the established RAVREDA project, with AMI
criteria. funds will complement the Roll
- Studies of sensitivity and resistance Back Malaria Strategy
completed in at least 5 municipalities providing coverage in remote
- Laboratory diagnosis quality control areas with high incidence of
implemented. malaria. The teams will be
mobile to reach scattered rural
population. The studies will
include from 42 to 50 cases
per month per cohort, in
around 10 nearby localities.
Three vehicles repaired Vehicles will have been repaired and The project will operate in
in operation. areas of difficult access year
round, which make it
necessary to use land and/or
water transportation
Maintenance of three vehicles and
minor repairs to three vehicles.
=10.000
Maintenance and repairs of
microscopes =1.500
Equipment, materials and inputs
provision for sentinel sites
laboratories. Microscopes (3),
lancets, stains, balances,
thermometers and slides
Requirements for quality control:
monitoring, meetings every 2
months of sentinel site technical
coordinators, national technical
coordinator and PAHO focal point.
Antimalarial drugs provision for
study purposes
(*) The physician will direct all activities: patient selection (according to the protocol clinical parameters), patient medical examinations (both admission and
house calls), direct administration of the treatment, monitoring and recording any collateral drug effects, collecting hematic samples for parasitological requirements
(day 0, 1, 2, 3, 4, 7, 14 and 28), give training to guarantee the sustainability of the project. The microscopy technologist will take the blood samples for malarial
exams of suspected cases and selected positive cases for the studies in "vivo" (continuous work includes holidays and weekends). Nursing auxiliary will also act as
guide, and will drive and pilot boats on the rivers, and malaria case detection.
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3. Definition of therapeutic -Therapeutic regimens in use
regimens to be evaluated in the evaluated, and antimalarial drugs to be
sentinel sites. evaluated in sentinels sites selected.
4. Selection of a (1) staff Staff member include as participants in The staff member will be an
member in charge of periodic the RAVREADA activities experienced physician
monitoring of activities in epidemiologist in the MSDS.
sentinel sites.
A.1.3. Provide 1. Workshop to explain all 1. Members of the network and all All selected personnel with Jan-02 Activities to be carried out
training to improve surveillance network activities. personnel hired for the study commitment to carry out the during 8 working days.
national capability surveillance network.
to conduct the
2. Workshop on antimalarial 2. The physicians hired for the Personnel participating in the
surveillance
therapies study and analysis of sentinel sites, at least three PAHO/WHO protocol development for
network of malaria
the (WHO/PAHO) protocol for persons in charge of regional execute the surveillance of antimalarial
drug resistance in
the supervised administration of services, and at least two drugs efficacy on Venezuela field
all target countries.
antimalarial drugs, use of the members from the surveillance trained.
forms for specific data. network coordination.
3. Workshop for microscopists 3. Participants include # of microscopists trained
training in malaria diagnosis, microscopists assigned to sentinel
including parasitemia sites; trainer of trainers, and at
quantification. least one member from
surveillance network coordination
A.1.4. Study 1. Data tabulation and analysis. Participants include National New treatment identified and endorsed Sep 02
findings reviewed Technical Advisory committee by the national technical advisory
alternative Surveillance network members and committee.
treatments sentinel site health workers
evaluated, and medical.
consensus on
appropriate 2.Surveillance network meeting
protocols reached. for analysis of results and
discussion from sentinel site
data.
3.Assesment of therapeutic
regimens administered
4.Asses strategy for alternative
schemes.
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Intermediate Result 2. Tools and approaches developed, adapted, tested and disseminated. Indicator: Number of sites identified in Brazil with trials of rapid tests for
malaria diagnosis initiated.
A2.1 Rapid tests for
malaria diagnosis
evaluated in
selected sites and
appraisal of their
cost-effectiveness
evaluated.
Intermediate Result 3. Partnerships to improve malaria control in the sub-region enhance. Indicator: Number of surveillance network of anti-malarial drug resistance activities
carried out with technical assistance or exchanges between target countries.
A3.1. Sub-regional Participate in regional/sub- Meeting reports. March-02
dialogue and regional meetings to discuss Sept-02
planning for work plans, agendas, evaluation
prevention and progress of the national
containment anti- networks and applied
malaria drug methodologies in technical
resistance assistance. (Include a mid term
facilitated. inter- country meeting)
A3.2. Centers of
excellence for
regional training
identified and
supported.
A3.3. South-to- Meetings with Guyana and Surveillance network staff Agreements and schedule Sep-02
south technical Suriname surveillance network
assistance and members to exchange
training activities information and establish
executed. agreements for technical
cooperation
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