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					                        Hot Topics in Internal Medicine 2009

                       New Mexico Chapter Scientific Meeting

                                  Friday, October 16

This case-base session will discuss familiarize participants with 15-20 high quality
practice changing papers published in the last six months. The audience will be
offered a choice of topics, including:

   Contemporary issues in the management of hypertension 1-6

    1. Arguedas JA, Perez MI, Wright JM. Treatment blood pressure targets for
    hypertension. Cochrane Database Syst Rev 2009:CD004349.
    2. Knutson KL, Van Cauter E, Rathouz PJ, et al. Association between sleep and
    blood pressure in midlife: the CARDIA sleep study. Arch Intern Med
    3. Law MR, Morris JK, Wald NJ. Use of blood pressure lowering drugs in the
    prevention of cardiovascular disease: meta-analysis of 147 randomised trials in
    the context of expectations from prospective epidemiological studies. BMJ
    4. Tindle HA, Chang YF, Kuller LH, et al. Optimism, cynical hostility, and incident
    coronary heart disease and mortality in the Women's Health Initiative.
    Circulation 2009;120:656-62.
    5. Wald DS, Law M, Morris JK, Bestwick JP, Wald NJ. Combination therapy
    versus monotherapy in reducing blood pressure: meta-analysis on 11,000
    participants from 42 trials. Am J Med 2009;122:290-300.
    6. Wright JM, Musini VM. First-line drugs for hypertension. Cochrane Database
    Syst Rev 2009:CD001841.

   Prevention and treatment of type 2 diabetes mellitus 7-16

    7. Blickle JF, Hancu N, Piletic M, et al. Insulin glargine provides greater
    improvements in glycaemic control vs. intensifying lifestyle management for
    people with type 2 diabetes treated with OADs and 7-8% A1c levels. The TULIP
    study. Diabetes Obes Metab 2009;11:379-86.
    8. Bolli GB, Kerr D, Thomas R, et al. Comparison of a multiple daily insulin
    injection regimen (basal once-daily glargine plus mealtime lispro) and
    continuous subcutaneous insulin infusion (lispro) in type 1 diabetes: a
    randomized open parallel multicenter study. Diabetes Care 2009;32:1170-6.
    9. Bunck MC, Diamant M, Corner A, et al. One-year treatment with exenatide
    improves beta-cell function, compared with insulin glargine, in metformin-
    treated type 2 diabetic patients: a randomized, controlled trial. Diabetes Care

    10. Buse JB, Rosenstock J, Sesti G, et al. Liraglutide once a day versus exenatide
    twice a day for type 2 diabetes: a 26-week randomised, parallel-group,
    multinational, open-label trial (LEAD-6). Lancet 2009;374:39-47.
    11. Buse JB, Wolffenbuttel BH, Herman WH, et al. DURAbility of basal versus
    lispro mix 75/25 insulin efficacy (DURABLE) trial 24-week results: safety and
    efficacy of insulin lispro mix 75/25 versus insulin glargine added to oral
    antihyperglycemic drugs in patients with type 2 diabetes. Diabetes Care
    12. Kawamori R, Tajima N, Iwamoto Y, Kashiwagi A, Shimamoto K, Kaku K.
    Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind
    trial in Japanese individuals with impaired glucose tolerance. Lancet
    13. Schweizer A, Dejager S, Bosi E. Comparison of vildagliptin and metformin
    monotherapy in elderly patients with type 2 diabetes: a 24-week, double-blind,
    randomized trial. Diabetes Obes Metab 2009;11:804-12.
    14. Shen L, Sun X, Yao L. Voglibose for prevention of type 2 diabetes mellitus.
    Lancet 2009;374:448-9.
    15. Skurtveit S, Strom H, Skrivarhaug T, Morland J, Bramness JG, Engeland A.
    Road traffic accident risk in patients with diabetes mellitus receiving blood
    glucose-lowering drugs. Prospective follow-up study. Diabet Med 2009;26:404-
    16. Young LH, Wackers FJ, Chyun DA, et al. Cardiac outcomes after screening for
    asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD
    study: a randomized controlled trial. JAMA 2009;301:1547-55.

   Screening for carotid artery disease and prevention of stroke 17-20

    17. Chappell F, Wardlaw J, Young G, et al. Carotid artery stenosis: accuracy of
    noninvasive tests - individual patient meta-analysis. Radiology 2009;251:493-
    18. Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in
    patients with atrial fibrillation. N Engl J Med 2009;361:1139-51.
    19. Lansberg MG, Schrooten M, Bluhmki E, Thijs VN, Saver JL. Treatment time-
    specific number needed to treat estimates for tissue plasminogen activator
    therapy in acute stroke based on shifts over the entire range of the modified
    Rankin Scale. Stroke 2009;40:2079-84.
    20. van Walraven C, Hart RG, Connolly S, et al. Effect of age on stroke prevention
    therapy in patients with atrial fibrillation: the atrial fibrillation investigators.
    Stroke 2009;40:1410-6.

   Effective medical management of patients with chronic pain syndromes 21-23

    21. Kroenke K, Bair MJ, Damush TM, et al. Optimized antidepressant therapy and
    pain self-management in primary care patients with depression and
    musculoskeletal pain: a randomized controlled trial. JAMA 2009;301:2099-110.

   22. Matthews P, Derry S, Moore RA, McQuay HJ. Topical rubefacients for acute
   and chronic pain in adults. Cochrane Database Syst Rev 2009:CD007403.
   23. Moore RA, Straube S, Wiffen PJ, Derry S, McQuay HJ. Pregabalin for acute
   and chronic pain in adults. Cochrane Database Syst Rev 2009:CD007076.

Common problems in women’s health: osteoporosis and incontinence 24-29

24.    Bell KJ, Hayen A, Macaskill P, et al. Value of routine monitoring of bone
mineral density after starting bisphosphonate treatment: secondary analysis of trial
data. BMJ 2009;338:b2266.
25.    Bischoff-Ferrari HA, Willett WC, Wong JB, et al. Prevention of nonvertebral
fractures with oral vitamin D and dose dependency: a meta-analysis of randomized
controlled trials. Arch Intern Med 2009;169:551-61.
26.    Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-
Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of
randomized controlled trials. JAMA 2005;293:2257-64.
27.    Cummings S, Martin JS, McClung M, et al. Denosumab for prevention of
fractures in postmmenopausal women with osteoporosis. N Engl J Med
28.    Hartmann K, McPheeters M, Biller D, et al. Treatment of overactive bladder in
women. Rockville, MD: Agency for Healthcare Research and Quality; 2009 August
29.    Tsai YC, Liu CH. The effectiveness of pelvic floor exercises, digital vaginal
palpation and interpersonal support on stress urinary incontinence: an
experimental study. Int J Nurs Stud 2009;46:1181-6.


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