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					                        Hot Topics in Internal Medicine 2009

                       New Mexico Chapter Scientific Meeting

                                  Friday, October 16



This case-base session will discuss familiarize participants with 15-20 high quality
practice changing papers published in the last six months. The audience will be
offered a choice of topics, including:

   Contemporary issues in the management of hypertension 1-6

    1. Arguedas JA, Perez MI, Wright JM. Treatment blood pressure targets for
    hypertension. Cochrane Database Syst Rev 2009:CD004349.
    2. Knutson KL, Van Cauter E, Rathouz PJ, et al. Association between sleep and
    blood pressure in midlife: the CARDIA sleep study. Arch Intern Med
    2009;169:1055-61.
    3. Law MR, Morris JK, Wald NJ. Use of blood pressure lowering drugs in the
    prevention of cardiovascular disease: meta-analysis of 147 randomised trials in
    the context of expectations from prospective epidemiological studies. BMJ
    2009;338:b1665.
    4. Tindle HA, Chang YF, Kuller LH, et al. Optimism, cynical hostility, and incident
    coronary heart disease and mortality in the Women's Health Initiative.
    Circulation 2009;120:656-62.
    5. Wald DS, Law M, Morris JK, Bestwick JP, Wald NJ. Combination therapy
    versus monotherapy in reducing blood pressure: meta-analysis on 11,000
    participants from 42 trials. Am J Med 2009;122:290-300.
    6. Wright JM, Musini VM. First-line drugs for hypertension. Cochrane Database
    Syst Rev 2009:CD001841.


   Prevention and treatment of type 2 diabetes mellitus 7-16

    7. Blickle JF, Hancu N, Piletic M, et al. Insulin glargine provides greater
    improvements in glycaemic control vs. intensifying lifestyle management for
    people with type 2 diabetes treated with OADs and 7-8% A1c levels. The TULIP
    study. Diabetes Obes Metab 2009;11:379-86.
    8. Bolli GB, Kerr D, Thomas R, et al. Comparison of a multiple daily insulin
    injection regimen (basal once-daily glargine plus mealtime lispro) and
    continuous subcutaneous insulin infusion (lispro) in type 1 diabetes: a
    randomized open parallel multicenter study. Diabetes Care 2009;32:1170-6.
    9. Bunck MC, Diamant M, Corner A, et al. One-year treatment with exenatide
    improves beta-cell function, compared with insulin glargine, in metformin-
    treated type 2 diabetic patients: a randomized, controlled trial. Diabetes Care
    2009;32:762-8.



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    10. Buse JB, Rosenstock J, Sesti G, et al. Liraglutide once a day versus exenatide
    twice a day for type 2 diabetes: a 26-week randomised, parallel-group,
    multinational, open-label trial (LEAD-6). Lancet 2009;374:39-47.
    11. Buse JB, Wolffenbuttel BH, Herman WH, et al. DURAbility of basal versus
    lispro mix 75/25 insulin efficacy (DURABLE) trial 24-week results: safety and
    efficacy of insulin lispro mix 75/25 versus insulin glargine added to oral
    antihyperglycemic drugs in patients with type 2 diabetes. Diabetes Care
    2009;32:1007-13.
    12. Kawamori R, Tajima N, Iwamoto Y, Kashiwagi A, Shimamoto K, Kaku K.
    Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind
    trial in Japanese individuals with impaired glucose tolerance. Lancet
    2009;373:1607-14.
    13. Schweizer A, Dejager S, Bosi E. Comparison of vildagliptin and metformin
    monotherapy in elderly patients with type 2 diabetes: a 24-week, double-blind,
    randomized trial. Diabetes Obes Metab 2009;11:804-12.
    14. Shen L, Sun X, Yao L. Voglibose for prevention of type 2 diabetes mellitus.
    Lancet 2009;374:448-9.
    15. Skurtveit S, Strom H, Skrivarhaug T, Morland J, Bramness JG, Engeland A.
    Road traffic accident risk in patients with diabetes mellitus receiving blood
    glucose-lowering drugs. Prospective follow-up study. Diabet Med 2009;26:404-
    8.
    16. Young LH, Wackers FJ, Chyun DA, et al. Cardiac outcomes after screening for
    asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD
    study: a randomized controlled trial. JAMA 2009;301:1547-55.

   Screening for carotid artery disease and prevention of stroke 17-20

    17. Chappell F, Wardlaw J, Young G, et al. Carotid artery stenosis: accuracy of
    noninvasive tests - individual patient meta-analysis. Radiology 2009;251:493-
    505.
    18. Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in
    patients with atrial fibrillation. N Engl J Med 2009;361:1139-51.
    19. Lansberg MG, Schrooten M, Bluhmki E, Thijs VN, Saver JL. Treatment time-
    specific number needed to treat estimates for tissue plasminogen activator
    therapy in acute stroke based on shifts over the entire range of the modified
    Rankin Scale. Stroke 2009;40:2079-84.
    20. van Walraven C, Hart RG, Connolly S, et al. Effect of age on stroke prevention
    therapy in patients with atrial fibrillation: the atrial fibrillation investigators.
    Stroke 2009;40:1410-6.


   Effective medical management of patients with chronic pain syndromes 21-23

    21. Kroenke K, Bair MJ, Damush TM, et al. Optimized antidepressant therapy and
    pain self-management in primary care patients with depression and
    musculoskeletal pain: a randomized controlled trial. JAMA 2009;301:2099-110.


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   22. Matthews P, Derry S, Moore RA, McQuay HJ. Topical rubefacients for acute
   and chronic pain in adults. Cochrane Database Syst Rev 2009:CD007403.
   23. Moore RA, Straube S, Wiffen PJ, Derry S, McQuay HJ. Pregabalin for acute
   and chronic pain in adults. Cochrane Database Syst Rev 2009:CD007076.


Common problems in women’s health: osteoporosis and incontinence 24-29

24.    Bell KJ, Hayen A, Macaskill P, et al. Value of routine monitoring of bone
mineral density after starting bisphosphonate treatment: secondary analysis of trial
data. BMJ 2009;338:b2266.
25.    Bischoff-Ferrari HA, Willett WC, Wong JB, et al. Prevention of nonvertebral
fractures with oral vitamin D and dose dependency: a meta-analysis of randomized
controlled trials. Arch Intern Med 2009;169:551-61.
26.    Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-
Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of
randomized controlled trials. JAMA 2005;293:2257-64.
27.    Cummings S, Martin JS, McClung M, et al. Denosumab for prevention of
fractures in postmmenopausal women with osteoporosis. N Engl J Med
2009;361:756-65.
28.    Hartmann K, McPheeters M, Biller D, et al. Treatment of overactive bladder in
women. Rockville, MD: Agency for Healthcare Research and Quality; 2009 August
2009.
29.    Tsai YC, Liu CH. The effectiveness of pelvic floor exercises, digital vaginal
palpation and interpersonal support on stress urinary incontinence: an
experimental study. Int J Nurs Stud 2009;46:1181-6.




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