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About This Document: The main compounds being researched are annexin-V and its derivatives, labeled with 18F and 64Cu for PET (12,13). Because caspases are responsible for the cell death program and are potentially suitable targets for the imaging of apoptosis in vivo, they are the current research focus of several academic and commercial sites. [...] the increasing numbers of moleculariy targeted therapies in advanced breast cancer suggest the need to introduce sensitive imaging (PET/CT) and diagnostic modalities to more appropriately monitor treatment benefit.

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Circulating Tumor Cells and PET

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Circulating Tumor Cells and PET

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