2467 BIOTECH Instruc Guide

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                        21st Century Instructional Guide for Career Technical Education

                                             Biotechnical Engineering
                                        Engineering and Technical Cluster
                                       Pre-engineering PLTW Concentration

Title:              Biotechnical Engineering (WEVIS 2467)

Standard Number:    Introduction to Biotechnical Engineering
ET.S.BIOTECH.1      Students will
                         research the history of Biotechnical Engineering.
                         examine the Biotechnical Engineering Industry.
                         explain lessons from Prometheus.
                         discover online research and communication skills.
                         demonstrate Biotechnical Engineering procedures.
Objectives:         Students will                                  Learning Plan & Notes to Instructor:
ET.O.BIOTECH.1.1    conduct a Biotechnology timeline web
                    quest to gather information about the
                    evolution of biotechnical engineering.
ET.O.BIOTECH.1.2    develop a scaled timeline illustrating major
                    biotechnical engineering milestones
                    through the use of the internet, available
                    hard copy resources, and their individual
                    milestone impact cards.
ET.O.BIOTECH.1.3    assess the impact of each milestone based
                    on their research.
ET.O.BIOTECH.1.4    select one milestone and create a timeline
                    event card with a description of the
                    development and its impact on future
                    biotechnical developments.
ET.O.BIOTECH.1.5    examine how the fields of biotechnology
                    are interconnected by the common
                    elements of living organisms.
ET.O.BIOTECH.1.6    determine the commercial companies as an
                    important component of new research in
ET.O.BIOTECH.1.7    examine the correlation between what is
                    happening in the financial markets and
                    what drives the biotechnology industry.
ET.O.BIOTECH.1.8    demonstrate independence and
                    cooperation as they work individually and
                    as a group to generate definitions of key
                    terms to be addressed in the lesson.
ET.O.BIOTECH.1.9    compare and contrast the differences
                    between values and morals.
ET.O.BIOTECH.1.10   examine the differences between morals
                    and ethics.
ET.O.BIOTECH.1.11   participate in role playing activities of a
                    bioethics case study to address and
                    personalize the different perspectives
ET.O.BIOTECH.1.12   analyze the bioethical issues that arise
                    when various technological advancements
                    create new options.
ET.O.BIOTECH.1.13   create and test a public opinion survey on
                    the bioethics of biotechnology.
ET.O.BIOTECH.1.14   create strategies for identifying key terms
                    that narrow their search topic.
ET.O.BIOTECH.1.15   examine on-line databases to search for
                    patents, people, business, government and
                    academic information.
ET.O.BIOTECH.1.16   communicate by E-mail including the use of
ET.O.BIOTECH.1.17   differentiate between an E-mail address
                    and a Web site address.
ET.O.BIOTECH.1.18   communicate ideas for designing a
                    development project using various drawing
                    methods, sketches, graphics or other
                    media collected and documented.
ET.O.BIOTECH.1.19   amend ideas, notes and presentations
                    based on personal review and feedback
                    from others and will document them.
ET.O.BIOTECH.1.20   communicate in daily journals the
                    advantages and disadvantages of various
                    information-gathering, communications and
                    design processes in the development of the
ET.O.BIOTECH.1.21   administer procedures for ensuring
                    accuracy and precision in measuring
ET.O.BIOTECH.1.22   demonstrate laboratory safety procedures.
Standard Number     Genomics
ET.S.BIOTECH.2      Students will
                         demonstrate reverse engineering.
                         research bioinformatics.
                         discover CSI Forensics.
                         develop alternative solutions.
                         research genes.
Objectives:         Students will                                Learning Plan & Notes to Instructor:
ET.O.BIOTECH.2.1    characterize the organic structures of the
                    building blocks of life: carbohydrates,
                    lipids, proteins and nucleic acids.
ET.O.BIOTECH.2.2    investigate the four letters of DNA, which
                    ones bond together and which are purines
                    and pyrimidines; demonstrate know how to
                    replicate DNA; determine that it is double
                    stranded and has a backbone made of
                    phosphates and sugar and determine that
                    DNA sequence determines traits.
ET.O.BIOTECH.2.3    design and create a DNA model.

ET.O.BIOTECH.2.4    determine their DNA model and validate it
                    represents the DNA appropriately.
ET.O.BIOTECH.2.5    investigate molecular techniques that are
                    used by bioinformaticists.
ET.O.BIOTECH.2.6    apply their knowledge of molecular
                    techniques, genetic databases analysis to
                    solve an outbreak scenario.
ET.O.BIOTECH.2.7    create a portfolio demonstrating the
                    research and integration of forensics with
ET.O.BIOTECH.2.8    design and construct a fuming chamber for
                    lifting prints from evidence.
ET.O.BIOTECH.2.9    analyze the technology utilized in the field
                    of forensics.
ET.O.BIOTECH.2.10   recreate a crime scene and solve the
ET.O.BIOTECH.2.11   collect evidence from a crime scene and
                    analyze the evidence for a mock trial.
ET.O.BIOTECH.2.12   conduct facial reconstruction and
                    experience the role of a forensic artist.
ET.O.BIOTECH.2.13   examine the role of an eye witness and
                    discover the accuracy in eye witness
ET.O.BIOTECH.2.14   develop a list of alternative solutions to
                    their stated problem, after Following a
                    review of the specifications and constraints
                    identified in their decision matrices
ET.O.BIOTECH.2.15   choose the appropriate technique for the
                    cell type or organism involved in a genetic
                    modification procedure.
ET.O.BIOTECH.2.16   apply their practical knowledge of genetic
                    engineering to the design of a novel and
                    beneficial application of the reporter gene,
                    green fluorescent protein.
ET.O.BIOTECH.2.17   determine the proper techniques for
                    isolating proteins.
Standard Number:   Bioprocesses
ET.S.BIOTECH.3     Students will
                       investigate biopharma: drug production and isolation.
                       research yeast mobile.
                       determine the requirements for aquaponics.
                       present formal presentations.
Objectives:        Students will                                Learning Plan & Notes to Instructor:
ET.O.BIOTECH.3.1   determine the bioethical and government
                   regulatory issues surrounding the practice
                   of using bioreactors for producing
                   pharmaceuticals and other useful products.
ET.O.BIOTECH.3.2   form a start-up pharmaceutical company
                   with an appropriate name that will attempt
                   to produce a pharmaceutical via previous
                   genetic engineering work followed by
                   scaled up growth of genetically modified
ET.O.BIOTECH.3.3   research and execute appropriate methods
                   of protein isolation necessary to purify GFP
                   from the modified bacteria produced in prior
ET.O.BIOTECH.3.4   determine the applications of fermentation
                   in food production and renewable energy.
ET.O.BIOTECH.3.5   design a method/instrumentation to be
                   used for measuring rates of fermentation.
ET.O.BIOTECH.3.6   research and test different variables which
                   affect CO2 production in yeast in order to
                   determine the ideal conditions for
ET.O.BIOTECH.3.7   design and run a yeast powered vehicle.
ET.O.BIOTECH.3.8   apply the appropriate statistical analysis
                   tools to their test results to ensure their
                   validity and significance.

ET.O.BIOTECH.3.9    identify, define, and implement needed
                    modifications to their design based upon
                    their ongoing research.
ET.O.BIOTECH.3.10   evaluate and explain the effectiveness of
                    their design at solving the problem that they
                    have defined.
ET.O.BIOTECH.3.11   appreciate the interaction between and
                    among abiotic and biotic factors in an
ET.O.BIOTECH.3.12   determine the requirements of an
                    aquaponics/hydroponics system.
ET.O.BIOTECH.3.13   use data collecting processes and
                    equipment (chemical solutions, laboratory
                    materials, computerized recording probes,
ET.O.BIOTECH.3.14   perform qualitative analysis of data as
                    criteria for goal achievement.
ET.O.BIOTECH.3.15   perform on-on-the-spot
                    repairs/modifications (trouble-shooting) of
                    equipment failure based on on-going
                    monitoring of system.
ET.O.BIOTECH.3.16   reflect on best practices.
ET.O.BIOTECH.3.17   discuss their findings in a formal
                    presentation before an audience.
Standard Number:    Environment
ET.S.BIOTECH.4      Students will
                         research environmental remediation.
                         discover aquaponics.
Objectives:         Students will                                   Learning Plan & Notes to Instructor:
ET.O.BIOTECH.4.1    research an invasive species in their area
                    to see why it is a problem and what is
                    currently being done. Examples include
                    Eurasion water milfoil, Zebra Mussels,

                   African Honeybee, Water Chestnut, Purple
                   Loosestrife, etc.
                   ·     What is the species?
                   ·     What type of environment does it
                   need to thrive?
                   ·     Why is it a problem in your area?
ET.O.BIOTECH.4.2   discover what is currently being done to
                   control the population and be able to
                   describe the success of that effort.
ET.O.BIOTECH.4.3   develop an action plan to monitor and
                   prevent the further movement of species
                   from one location to another.
ET.O.BIOTECH.4.4   design a control mechanism (mechanical,
                   biological, chemical) to prevent the invasive
                   species from destroying the use of the
                   environment and harming native species.
ET.O.BIOTECH.4.5   present their findings to the class for
                   evaluation of their approach.
ET.O.BIOTECH.4.6   determine the relevance of measuring
                   phytoplankton continuously in the bodies of
ET.O.BIOTECH.4.7   generate and utilize a standard curve of the
                   absorbance of chlorophyll A and direct cell
ET.O.BIOTECH.4.8   describe the optical components of a
Standard Number:   Biomedical
ET.S.BIOTECH.5     Students will
                        demonstrate the use of biomedical devices.
                        research orthopedic implants.
                        design a cardiovascular device for imaging.
Objectives:        Students will                               Learning Plan & Notes to Instructor:
ET.O.BIOTECH.5.1   demonstrate the application of personal

                    protective equipment (PPE).
ET.O.BIOTECH.5.2    examine the application of engineering
                    design principles by improving upon
                    existing hospital designs or surgical
                    equipment designs.
ET.O.BIOTECH.5.3    demonstrate the application of product
                    liability, product reliability, product
                    reusability, and product failure.
ET.O.BIOTECH.5.4    use vocabulary terms in context and
                    complete a vocabulary test.
ET.O.BIOTECH.5.5    analyze case studies and present their
                    opinions to jurors, which are made up of
                    other class members.
ET.O.BIOTECH.5.6    develop a portfolio identifying anatomical
                    joint features and movements.
ET.O.BIOTECH.5.7    build a joint model with the same degrees
                    of freedom as the human counterpart.
ET.O.BIOTECH.5.8    design and sketch a new joint replacement
                    and solid model approved sketches.
ET.O.BIOTECH.5.9    develop a materials and process cost list
                    for design.
ET.O.BIOTECH.5.10   obtain a surgical estimate for joint
ET.O.BIOTECH.5.11   determine the function(s) of the major
                    muscles of the body.
ET.O.BIOTECH.5.12   research the major divisions and
                    subdivisions of the skeletal system.
ET.O.BIOTECH.5.13   compare diseases and disorders
                    associated with the skeletal system.
ET.O.BIOTECH.5.14   synthesize skeletal system concepts with
                    the design process for engineering joints.
ET.O.BIOTECH.5.15   investigate heart diseases and disorders.
ET.O.BIOTECH.5.16   sketch and provide a solid model of heart
                    chambers and valves.
ET.O.BIOTECH.5.17   research procedures involving artificial

                      heart surgery and present the cost of a
                      proposed noninvasive implant.
ET.O.BIOTECH.5.18     research and create a set of improvements
                      for imaging techniques.
ET.O.BIOTECH.5.19     design a portable ECG monitor and study
                      the electrical aspects associated to the
ET.O.BIOTECH.5.20     research and design improvements in heart
                      implants and/or instruments.
ET.O.BIOTECH.5.21     perform a virtual heart surgery to better
                      understand the instruments and implants in
                      need of improving.
Standard Number:      Student Organization Participation
ET.S.BIOTECH.6        Students will participate in a local student organization.
Objectives:           Students will                                  Learning Plan & Notes to Instructor:
ET.O.BIOTECH.6.1      assess the purposes and goals of student
ET.O.BIOTECH.6.2      demonstrate leadership skills through
                      participation in student organization
                      activities such as meetings, programs,
                      projects and competitions.
ET.O.BIOTECH.6.3      evaluate the benefits and responsibilities of
                      participation in student, professional and
                      civic organizations as an adult.
21st Century Skills   Learning Skills & Technology Tools            Teaching Strategies          Evidence of Success
                                                                    Culminating Activity
Information and       21C.O.9-      Student recognizes
Communication         12.1.LS1      information needed for
Skills:                             problem solving, can
                                    efficiently browse, search and
                                    navigate online to access
                                    relevant information,
                                    evaluates information based
                                    on credibility, social,
           economic, political and/or
           ethical issues, and presents
           findings clearly and
           persuasively using a range of
           technology tools and media.
21C.O.9-   Student analyzes and
12.1.LS2   interprets visuals and
           recognizes the impact digital
           media influences (e.g. design,
           technique, and rate of speed)
           have on audiences. The
           student’s visual products
           reflect a sophisticated
           understanding of subject,
           digital media and design
21C.O.9-   Student creates information
12.1.LS3   using advanced skills of
           analysis, synthesis and
           evaluation and shares this
           information through a variety
           of oral, written and multimedia
           communications that target
           academic, professional and
           technical audiences and
21C.O.9-   Student makes informed
12.1.TT1   choices among available
           advanced technology
           systems, resources and
           services (e.g., global
           positioning software, graphing
           calculators, personal digital
           assistants, web casting,
           online collaboration tools) for
           completing curriculum
           assignments and projects and
           for managing and
21C.O.9-   Student routinely applies         Students will utilize computer Completed assignments
12.1.TT2   keyboarding skills,               software on a routine basis
           keyboarding shortcut              to complete assignments.
           techniques, and mouse skills
           with facility, speed and
21C.O.9-   Student uses advanced
12.1.TT3   utilities (e.g., zipping or
           compressing files, file level
           anti-virus scans), converts
           files to different formats (e.g.,
           .doc, .xls, .mdb, .htm, .pdf)
           and saves finished products
           to multiple media sources
           (e.g., CDRW, DVDR, USB
           drives, shared folders, web-
           based file storage).
21C.O.9-   Student uses audio, video,
12.1.TT4   pictures, clip art, moviemaker
           programs, webpage design
           software, electronic
           documents and other files to
           collaborate for the creation of
           electronic products that
           inform multiple audiences
           both inside and outside the
           school environment.
21C.O.9-   Student uses advanced
12.1.TT5   features of word processing
           software (e.g., outline, table
           of contents, index feature,
           draw tool, headers and
           footers, track changes,
           macros, hyperlinks to other
           file formats, etc.).
21C.O.9-   Student uses advanced
12.1.TT6   features and utilities of
           spreadsheet software, (e.g.,
           formulas, filters, pivot tables,
           pivot charts, macros,
           conditional formatting), to
           perform calculations and to
           organize, analyze and report
21C.O.9-   Student uses advanced
12.1.TT7   features and utilities of
           presentation software (e.g.,
           slide transitions, master
           slides, narrations and timings,
           creating web-enabled
           presentations, creating a non-
           linear presentation) to
           communicate ideas to
           multiple audiences.
21C.O.9-   Student uses advanced
12.1.TT8   features and utilities of
           database software (e.g., to
           create tables, forms, perform
           table relationships, advanced
           queries, and simple reports)
           to test hypotheses or
           research questions and to
           report results.
21C.O.9-   Student uses advanced
12.1.TT9   telecommunication tools (e.g.,
           email, video conferencing,
           interactive websites,
                                newsgroups, video phones,
                                chats) to create collaborative
                                projects that are relevant to
                                real world situations and
                                contribute to the
                                communication process
                                among various groups.
                    21C.O.9-    Student implements various
                    12.1.TT10   Internet search techniques
                                (e.g., Boolean searches,
                                meta-searches, web bots) to
                                gather information; student
                                evaluates the information for
                                validity, appropriateness,
                                content, bias, currency, and
                    21C.O.9-    Student implements various
                    12.1.TT10   Internet search techniques
                                (e.g., Boolean searches,
                                meta-searches, web bots) to
                                gather information; student
                                evaluates the information for
                                validity, appropriateness,
                                content, bias, currency, and
                    21C.O.9-    Student imports and exports
                    12.1.TT11   multiple data formats and
                                integrates to multiple
                                productivity programs (e.g.,
                                exports comma delimited
                                files, standard data formats)
                                and understands
                                transferability of data among
                                different programs.
Thinking and        21C.O.9-    Student engages in a critical
Reasoning Skills:   12.2.LS1    thinking process that supports
           synthesis and conducts
           evaluation using complex
21C.O.9-   Student draws conclusions
12.2.LS2   from a variety of data sources
           to analyze and interpret
21C.O.9-   Student visualizes the
12.2.LS4   connection between
           seemingly unrelated ideas
           and independently produces
           solutions that are fresh,
           unique, original and well
           developed. Student shows
           capacity for originality,
           concentration, commitment to
           completion, and persistence
           to develop unique and cogent
21C.O.9-   Student knows how to find
12.2.TT1   information necessary to
           solve advanced problems
           related to hardware, software,
           networks, and connections
           (e.g., by accessing online
           help, Internet searches,
           technical documentation,
           system utilities, and
           communication with technical

               21C.O.9-   Student collaborates with
               12.2.TT2   peers, experts, and others to
                          contribute to a content-related
                          knowledge base by using
                          technology to compile,
                          synthesize, produce, and
                          disseminate information,
                          models, and other creative
               21C.O.9-   Student uses multiple
               12.2.TT3   electronic sources of
                          information and multiple
                          technology tools and resource
                          tools (e.g., digital cameras,
                          graphing calculators, probes,
                          mp3 players, handheld
                          devices, other emerging
                          technologies, simulations,
                          models, browsers, word
                          processing, authoring tools,
                          spreadsheets, databases) to
                          collaborate with others, to
                          formulate a hypothesis, to
                          solve problems, make
                          decisions, and present and
                          justify the solutions.
               21C.O.9-   Student uses technology tools
               12.2.TT4   and multiple media sources to
                          analyze a real-world problem,
                          design and implement a
                          process to assess the
                          information, and chart and
                          evaluate progress toward the
Personal and   21C.O.9-   Student remains composed

Workplace Skills:   12.3.LS1   and focused, even under
                               stress, willingly aligns his/her
                               personal goals to the goals of
                               others when appropriate,
                               approaches conflict from win-
                               win perspective, and derives
                               personal satisfaction from
                               achieving group goals.
                    21C.O.9-   Student independently
                    12.3.LS2   considers multiple
                               perspectives and can
                               represent a problem in more
                               than one way, quickly and
                               calmly changes focus and
                               goals as the situation
                               requires, and actively seeks
                               innovations (e.g. technology)
                               that will enhance his/her
                    21C.O.9-   Student demonstrates
                    12.3.LS3   ownership of his/her learning
                               by setting goals, monitoring
                               and adjusting performance,
                               extending learning, using
                               what he/she has learned to
                               adapt to new situations, and
                               displaying perseverance and
                               commitment to continued
                    21C.O.9-   Student demonstrates ethical
                    12.3.LS4   behavior and works
                               responsibly and
                               collaboratively with others in
                               the context of the school and
                               the larger community, and
                               he/she demonstrates civic
           responsibility through
           engagement in public
           discourse and participation in
           service learning.
21C.O.9-   Student exhibits positive           Students will participate in   SkillsUSA or TSA
12.3.LS5   leadership through                  SkillsUSA or TSA and           meeting minutes
           interpersonal and problem-          become a chapter or state
           solving skills that contribute to   officer or serve as            Class work
           achieving the goal. He/she          chairpersons of committees.
           helps others stay focused,          Students will work
           distributes tasks and               cooperatively in the
           responsibilities effectively,       classroom taking leadership
           and monitors group progress         roles.
           toward the goal without
           undermining the efforts of
21C.O.9-   Student maintains a strong
12.3.LS6   focus on the larger project
           goal and frames appropriate
           questions and planning
           processes around goal. Prior
           to beginning work, student
           reflects upon possible
           courses of action and their
           likely consequences; sets
           objectives related to the
           larger goal; and establishes
           benchmarks for monitoring
           progress. While working on
           the project, student adjusts
           time and resources to allow
           for completion of a quality
21C.O.9-   Student protects software,
12.3.TT1   hardware and network
           resources from viruses,
           vandalism, and unauthorized
           use and employs proper
           techniques to access, use
           and shut down technology
21C.O.9-   Student works collaboratively
12.3.TT2   to acquire information from
           electronic resources,
           conducts online research, and
           evaluates information as to
           validity, appropriateness,
           comprehensiveness and bias.

21C.O.9-   Student evaluates current
12.3.TT3   trends in information
           technology, discusses the
           potential social, ethical,
           political, and economic impact
           of these technologies, and
           analyzes the advantages and
           disadvantages of widespread
           use and reliance on
           technology in the workplace
           and society.
21C.O.9-   Student adheres to              Students will sign and    Ethical use of technology
12.3.TT4   acceptable use policy and       adhere to a school-wide
           displays ethical behaviors      acceptable use policy.
           related to acceptable use of
           information and
           communication technology
           (e.g., privacy, security,
           copyright, file-sharing,
           plagiarism); student predicts
           the possible cost and effects
           of unethical use of technology
           (e.g., consumer fraud,
           intrusion, spamming, virus
           settling, hacking) on culture
           and society; student identifies
           the methodologies that
           individuals and businesses
           can employ to protect the
           integrity of technology

21C.O.9-   Student models ethical            Students will sign and    Ethical use of technology
12.3.TT5   behavior relating to security,    adhere to a school-wide
           privacy, computer etiquette,      acceptable use policy.
           passwords and personal
           information and demonstrates
           an understanding of copyright
           by citing sources of
           copyrighted materials in
           papers, projects and multi-
           media presentations. Student
           advocates for legal and
           ethical behaviors among
           peers, family, and community
           regarding the use of
           technology and information.
21C.O.9-   Student evaluates and
12.3.TT6   applies technology tools for
           research, information
           analysis, problem-solving,
           content learning, decision
           making, and lifelong learning.
21C.O.9-   Student protects his/her
12.3.TT7   identity online and in email
           and/or websites, limits the
           distribution of personal
           information/pictures, and
           evaluates the authenticity of
           emails that solicit personal
           information. Student identifies
           the methodologies that
           individuals and businesses
           can employ to protect the
           integrity of technology

                  21C.O.9-   Student uses technology to
                  12.3.TT8   seek strategies and
                             information to address limits
                             in their own knowledge.
                    Learning Skills & Technology Tools             Teaching Strategies       Evidence of Success
                                                                  Culminating Activity
Entrepreneurial               Student understands the         Students take available on-    Results from self-quizzes
Skills:                       personal traits/behaviors       line quizzes to learn their
                              associated with successful      entrepreneurial aptitudes
                              entrepreneurial performance.    such as:

                             Student understands            Students will utilize computer Completed assignments
                             concepts and procedures        software and hardware to
                             needed for basic computer      complete assignments.
                             Student understands            Students will interview        Interviews/reports
                             concepts and strategies        draftspersons to learn how
                             needed for career exploration, their career paths developed.
                             development and growth.
                                                     Culminating Assessment:
Culminating       End of Concentration Performance Evaluation
                  Students will participate in TSA’s competitive events: Architectural Model, Computer aided Design 2D,
                  Architecture and Computer Aided Design Animation, Architecture, Technical Sketching and
                  Application, Leadership Development Contests: Career Comparisons, Written and Oral Chapter
                  Team, Extemporaneous Presentation, and Prepared Presentation

                  Students will participate in SkillsUSA’s competitive events: Architectural Drafting, Leadership
                  Development Contests: Action Skills, American Spirit, Chapter Business Procedure, Chapter Display,
                  Community Service, Extemporaneous Speaking, Job Interview, Job skill Demonstration A, Job Skill
                  Demonstration B, Occupational Health and Safety, Opening and Closing Ceremonies, Outstanding
                  Chapter, Prepared Speech, Promotional Bulletin Board, and Quiz Bowl
                                                              Links and Other Resources
Links and Other   Related Websites:
                  Pathways to Success

                  U.S. Department of Labor in the 21st Century

                  Advanced Distributed Learning

                  America's Career InfoNet

                  America's Job Bank

                  America's Service Locator


                  Employment & Training Administration

                  The Job Accommodation Network (JAN)

                  Monthly Labor Review Online: Labor Force Archives

                  Occupational Information Network

                  Office of Disability Employment Policy

            Career Voyages

            Workforce West Virginia

            West Virginia Earn A Degree Graduate Early (EDGE)

            West Virginia Career and Technical Education

Contacts:   CTE Teachers: See CTE Directory
            Cluster Coordinator: Kathy Gillman,
            OCTI Assistant Executive Director and EOCTST Coordinator: Donna Burge-Tetrick
            OCTI Executive Director: Gene Coulson


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