Neu r al in lis t o f in lis t o f in lis t o f in lis t o f
SGD Fo u r ier
ORF n am e n etw o r k Know n Zh ao Sp ellm an Ch o SGD Gen e Des c r ip tio n
n am e score
o u tp u t g en es g en es g en es g en es
YIL169C 0.98 2.8 C Protein of unknown function
YNL322C KRE1 0.98 1.7 cell wall beta-glucan assembly
YJL078C PRY3 0.98 5.5 S C Pathogen Related in Sc, contains homology to the plant PR-1 class of pathogen related proteins. The protein sequence is over 60% identical with the Pry2p & Pry3
YDL038C 0.98 5.3 Protein of unknown function
YOR009W TIR4 0.98 1.0 Protein of unknown function
YJR151C DAN4 0.97 1.3 Delayed Anaerobic Gene
YOL155C 0.97 3.0 C Protein of unknown function
YLR286C CTS1 0.97 9.3 K S C Endochitinase
YOL030W GAS5 0.97 4.1 Z S Hypothetical ORF
YOR220W 0.97 2.5 Protein of unknown function
YNR044W AGA1 0.97 6.5 K S anchorage subunit of a-agglutinin
YGR023W MTL1 0.97 1.8 Mid-Two Like 1
YMR317W 0.97 2.1 Protein of unknown function
YCR089W FIG2 0.97 3.4 Factor-Induced Gene 2: expression is induced by the mating pheromones, a and alpha factor; required for efficient mating
YLR194C 0.96 5.4 S Protein of unknown function
YIL011W TIR3 0.96 2.6 S TIP1-related
YGR161C 0.96 2.4 Protein of unknown function
YBR067C TIP1 0.96 5.9 K Z S C cold- and heat-shock induced protein of the Srp1p/Tip1p family of serine-alanine-rich proteins
YNL327W EGT2 0.96 8.7 K S cell-cycle regulation protein, may be involved in the correct timing of cell separation after cytokinesis
YLR332W MID2 0.96 1.5 Protein required for mating
YNR067C DSE4 0.96 6.3 S C Daughter Specific Expression 4
YOR382W FIT2 0.96 1.8 FIT1, FIT2, and FIT3 code for mannoproteins that are incorporated into the cell wall via glycosylphosphatidylinositol anchors.
YLR390W-A CCW14 0.96 2.7 Secretory Stress Response protein
YHR143W DSE2 0.96 7.3 S Daugher Specific Expression 2
YFR054C 0.96 1.6 Protein of unknown function
YDL211C 0.96 3.3 S Protein of unknown function
YLR353W BUD8 0.96 4.2 Z S C marks and directs bud emergence to the distal pole of diploid cells
YNL283C WSC2 0.95 5.8 Z S cell wall integrity and stress response component 2
YDR349C YPS7 0.95 1.4 Gpi-anchored aspartic protease (Yapsin 7)
YHR212C 0.95 0.8 Protein of unknown function
YOL105C WSC3 0.95 1.2 cell wall integrity and stress response component 3
YIL117C PRM5 0.95 3.7 S pheromone-regulated membrane protein
YDR534C FIT1 0.95 1.5 FIT1, FIT2, and FIT3 code for mannoproteins that are incorporated into the cell wall via glycosylphosphatidylinositol anchors.
YIR016W 0.95 0.8 Protein of unknown function
YDR055W PST1 0.95 5.5 S Protoplasts-secreted
YLR120C YPS1 0.95 1.8 Gpi-anchored aspartic protease (Yapsin 1)
YGL028C SCW11 0.95 8.2 S C Soluble Cell Wall protein
YDR451C YHP1 0.95 5.3 S C Protein of unknown function
YJL158C CIS3 0.94 4.7 S cik1 suppressor
YJR004C SAG1 0.94 3.8 S alpha-agglutinin
YNL176C 0.94 3.7 Z S C Protein of unknown function
YGL035C MIG1 0.94 1.1 Transcription factor involved in glucose repression
YOR383C FIT3 0.94 2.0 S FIT1, FIT2, and FIT3 code for mannoproteins that are incorporated into the cell wall via glycosylphosphatidylinositol anchors.
YMR307W GAS1 0.94 5.6 K S Glycophospholipid-anchored surface protein
YDL191W RPL35A 0.94 2.0 Homology to rat L35
YDL136W RPL35B 0.94 2.3 Homology to rat L35
YMR233W TRI1 0.94 0.8 Topoisomerase 1 and RAD52 epistasis group Interactions
YBR130C SHE3 0.94 1.9 Z cytoplasmic protein involved in mother-specific HO expression
YOR279C RFM1 0.94 0.8 Repression Factor of MSE
YNL074C MLF3 0.94 0.8 Protein of unknown function
YLR121C YPS3 0.94 5.5 S C Gpi-anchored aspartic protease (Yapsin 3)
YGL056C SDS23 0.94 1.0 homolog of pombe SDS23; localizes to spindle pole body
YEL040W UTR2 0.93 2.7 S (alias: Congo Red Hypersensitivity)
YOR247W SRL1 0.93 4.8 S Suppressor of Rad53 null Lethality
YER028C 0.93 1.8 Protein of unknown function
YNL053W MSG5 0.93 2.5 C Tyrosine protein phosphatase involved in adaptation response to pheromone
YGL032C AGA2 0.93 4.1 S adhesion subunit of a-agglutinin
YOR010C TIR2 0.93 1.6 cold-shock induced protein of the Srp1p/Tip1p family of serine-alanine-rich proteins
YDR439W LRS4 0.93 1.2 Loss of rDNA silencing
YKR092C SRP40 0.93 1.9 Suppressor of mutant AC40 subunit of RNA polymerase I and III (high serine)
YLR457C NBP1 0.93 2.9 S C Nap1p Binding Protein
YJL053W PEP8 0.93 1.0 Plays a role in delivery of proteins to the vacuole
YGL003C CDH1 0.93 1.5 CDC20 homolog 1
YNL042W BOP3 0.92 2.3 bypass of PAM1
YLR040C 0.92 2.6 S Protein of unknown function
YHR214W 0.92 2.3 Protein of unknown function
YAR066W 0.92 1.7 Protein of unknown function
YIL123W SIM1 0.92 6.0 Z S (putative) invovled in control of DNA replication
YFR022W 0.92 2.2 Protein of unknown function
YPL014W 0.92 3.5 S C Protein of unknown function
YPR171W 0.92 1.1 Protein of unknown function
YOR233W KIN4 0.92 2.1 protein kinase
YPL155C KIP2 0.92 3.3 Z S kinesin-related protein
YML041C VPS71 0.92 0.9 Protein of unknown function
YKL079W SMY1 0.92 2.0 not believed to act as a kinesin, colocalizes with Myo2p
YGR035C 0.92 4.5 S C Protein of unknown function
YJR150C DAN1 0.92 2.6 Delayed Anaerobic
YNR014W 0.92 1.8 Protein of unknown function
YLR394W CST9 0.92 1.5 Chromosome STability; involved in meiotic chromosome synapsis
YIR019C MUC1 0.92 1.5 Required for invasion and pseudohyphae formation in response to nitrogen starvation
YLR265C NEJ1 0.92 0.9 Nonhomologous End-Joining regulator 1; Repressed by MAT heterozygosity; Interacts with Lif1p in a yeast two-hybrid assay
YKR102W FLO10 0.92 1.9 Protein with similarity to flocculation protein Flo1p
YDR447C RPS17B 0.92 1.3 Homology to rat ribosomal protein S17
YLR042C 0.91 1.6 Protein of unknown function
YKR091W SRL3 0.91 3.0 S Suppressor of Rad53 null Lethality
YNL078W NIS1 0.91 5.3 S C Protein of unknown function
YDR420W HKR1 0.91 1.3 cell surface protein that may regulate cell wall beta-glucan synthesis and bud site selection; Hanenula mrakii killer toxin-resistance protein
YGL162W SUT1 0.91 3.0 S Involved in sterol uptake
YOR019W 0.91 0.8 Protein of unknown function
YKR010C TOF2 0.91 4.2 Z S C topoisomerase I interacting factor 2
YBR162C TOS1 0.91 2.6 Target of SBF
YDL129W 0.91 1.6 Protein of unknown function
YGR074W SMD1 0.91 1.7 Homolog of human core snRNP protein D1, involved in snRNA maturation
YMR188C 0.91 2.1 Protein of unknown function
YMR268C PRP24 0.91 1.1 U4/U6 snRNA-associated splicing factor
YGL259W YPS5 0.91 2.4 Gpi-anchored aspartic protease (Yapsin 5)
YGR091W PRP31 0.90 0.9 pre-mRNA splicing protein
YGR014W MSB2 0.90 3.7 Z S putative integral membrane protein
YER011W TIR1 0.90 2.4 K Cold-shock induced protein of the Srp1p/Tip1p family of serine-alanine-rich proteins. Encodes a stress-response cell wall mannoprotein and this gene is downregu
YAL065C 0.90 2.0 Protein of unknown function
YBR203W 0.90 1.7 Protein of unknown function
YOR372C NDD1 0.90 2.8 Z S Nuclear Division Defective 1
YCL063W 0.90 4.1 S C Protein of unknown function
YOL036W 0.90 1.0 Protein of unknown function
YGR279C SCW4 0.90 4.2 S C Soluble Cell Wall protein
YLR313C SPH1 0.90 5.9 Z S C SPa2-Homolog; protein involved in shmoo formation and required for bipolar bud site selection (GB:AF008236).
YDR277C MTH1 0.90 1.6 C Negative regulator of HXT gene expression
YDR169C STB3 0.90 1.7 binds Sin3p in two-hybrid assay
YDL028C MPS1 0.90 1.8 Required for spindle pole body duplication and a mitotic checkpoint function.
YHR004C NEM1 0.90 0.8 Nuclear Envelope Morphology
YDR223W 0.90 1.0 Protein of unknown function
YOR324C 0.90 3.3 S Protein of unknown function
YHR211W FLO5 0.90 0.8 FLO5- and FLO8-determined flocculation are considerably less sensitive to mannose than FLO1-determined flocculation.
YLR094C GIS3 0.90 1.6 GIG3 suppressor
YOL060C MAM3 0.90 1.4 putative hemolysin-like protein with three transmembrane domains
YDL194W SNF3 0.90 1.3 glucose sensor
YJR115W 0.90 0.8 Protein of unknown function
YML109W ZDS2 0.90 2.7 S C multicopy suppressor of a sin4 defect
YDR077W SED1 0.90 3.7 K S putative cell surface glycoprotein
YDR200C VPS64 0.90 1.7 Protein of unknown function
YDR144C MKC7 0.89 2.0 S protease involved in protein processing that shares functions with Yap3 and Kex2
YDR507C GIN4 0.89 4.5 S C Growth inhibitory gene
YBR215W HPC2 0.89 1.1 Protein required for normal cell-cycle regulation of histone gene transcription
YJL160C 0.89 2.0 Protein of unknown function
YOR023C AHC1 0.89 1.7 S Ada Histone acetyltransferase complex component
YDL127W PCL2 0.89 6.6 K Z S C Interacts with cyclin-dependent kinase PHO85 to form kinase complex with G1-periodic activity involved in cell cycle progression
YKL006C-A SFT1 0.89 1.1 Required for transport of proteins between an early and a later golgi compartment. possible NSF attachment protein receptor (V-SNARE)
YOR058C ASE1 0.89 4.5 K Z S C essential for anaphase spindle elongation
YGR079W 0.89 1.1 Protein of unknown function
YJL128C PBS2 0.89 1.1 Involved in osmoregulation, member of the HOG1 mitogen-activated protein kinase (MAPK) cascade
YDL048C STP4 0.89 3.3 S C Involved in pre-tRNA splicing and in uptake of branched-chain amino acids
YDR524C AGE1 0.89 1.1 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector
YDR379W RGA2 0.89 1.6 contains a Rho-GAP domain and two LIM domains, similar to Rga1p and all known Rho-GAPs
YPL070W 0.89 1.1 Protein of unknown function
YBR156C SLI15 0.89 1.9 C Mitotic spindle protein involved in chromosome segregation.
YDL197C ASF2 0.89 4.1 K Z S C anti-silencing protein that causes depression of silent loci when overexpressed
YOR288C MPD1 0.89 2.0 Disulfide isomerase related protein
YPR023C EAF3 0.89 1.3 Esa1p-Associated Factor
YDR422C SIP1 0.89 1.2 SNF1 protein kinase substrate
YBR214W SDS24 0.89 1.8 Similar to S. pombe SDS23, suppresses DIS2, localized to the nucleus
YHR096C HXT5 0.89 2.3 Member of superfamily of monosaccharide transporters
YDR528W HLR1 0.89 4.5 Z S LRE1 homolog
YOR014W RTS1 0.89 1.1 B-type regulatory subunit of protein phosphatase 2A (PP2A)
YOR008C SLG1 0.89 1.3 cell wall integrity and stress response component 1
YPR075C OPY2 0.88 3.4 S imparts Far- phenotype
YOL070C 0.88 3.4 S C Protein of unknown function
YKL175W ZRT3 0.88 1.8 Protein of unknown function
YBR142W MAK5 0.88 1.7 Necessary for maintenance of dsRNA killer plasmids. Is predicted to encode an DEAD-box RNA helicase
YPR083W MDM36 0.88 1.6 Mitochondrial Distribution and Morphology
YGL113W SLD3 0.88 0.9 synthetic lethality with dpb11-1; Sld3p interacts with Cdc45 and is required for initiation of DNA replication.
YNR039C ZRG17 0.88 1.0 zinc-regulated gene
YNL096C RPS7B 0.88 0.9 Homology to human S7 and Xenopus S8
YIL015W BAR1 0.88 1.1 extracellular protease synthesized in a-cells that cleaves and inactivates alpha factor
YGL209W MIG2 0.88 2.8 S Involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YKR045C 0.88 1.0 Protein of unknown function
YBR119W MUD1 0.88 1.1 U1 snRNP A protein
YDL037C 0.88 8.3 S Protein of unknown function
YOL091W SPO21 0.88 2.0 sporulation defective
YLL021W SPA2 0.88 2.3 C spindle pole antigen
YDR309C GIC2 0.88 4.2 K S C Gtpase-interacting component 2
YBR255W 0.88 1.3 Protein of unknown function
YGR027C RPS25A 0.88 0.9 Homology to rat S25
YDR436W PPZ2 0.88 1.6 serine-threonine phosphatase Z
YLR003C 0.88 1.4 Protein of unknown function
YNL272C SEC2 0.88 2.1 C Protein with coiled-coil domain essential for vesicular transport
YLL038C ENT4 0.88 1.5 epsin N-terminal homology-containing protein
YBL031W SHE1 0.88 2.1 Product of gene unknown
YPR056W TFB4 0.88 1.3 RNA polymerase transcription initiation TFIIH (factor b), 37 kDa subunit
YJR021C REC107 0.88 1.2 meiotic recombination protein
YHR049C-A 0.88 1.1 Protein of unknown function
YOL012C HTZ1 0.88 3.5 Z S C Histone-related protein that can suppress histone H4 point mutation
YOR018W ROD1 0.88 3.2 Z S Resistance to o-dinitrobenzene, calcium, and zinc
YGL171W ROK1 0.88 1.1 contains domains found in the DEAD protein family of ATP-dependent RNA helicases; high-copy suppressor of kem1 null mutant
YDR227W SIR4 0.87 1.4 Sir4 binding to Rap1 initiates the sequential association of Sir and other proteins, allowing the subsequent spreading of heterochromatin proteins along the chromo
YOR355W GDS1 0.87 2.3 S involved in nuclear control of mitochondria
YOR295W UAF30 0.87 1.0 Topoisomerase 1 and RAD52 epistasis group Interactions
YLR031W 0.87 1.4 Protein of unknown function
YPL158C 0.87 6.1 S C Protein of unknown function
YPL039W 0.87 0.9 Protein of unknown function
YLR333C RPS25B 0.87 1.3 Homology to rat S25; belongs to the S25E family of ribosomal proteins
YGR068C 0.87 1.7 Protein of unknown function
YKL176C LST4 0.87 1.1 required for amino acid permease transport from the Golgi to the cell surface. involved in regulated secretion/recycling of nitrogen regulated permeases.
YNL269W 0.87 2.1 Protein of unknown function
YKR019C IRS4 0.87 1.0 Increased rDNA silencing
YLR035C MLH2 0.87 1.6 Mutl Homolog
YKL108W SLD2 0.87 5.4 Z S C Synthetically lethal with dpb11-1; required for DNA replication
YDL239C ADY3 0.87 2.7 Accumulation of dyads
YHL031C GOS1 0.87 1.3 SNARE protein with a C-terminal membrane anchorGOlgi Snare
YPL074W YTA6 0.87 2.4 Member of CDC48/PAS1/SEC18 family of ATPases
YDL074C BRE1 0.87 1.3 putative coiled-coil protein with RING-finger and myosin-like domains
YCR067C SED4 0.87 1.2 Sed4p is an integral ER membrane protein, which, along along with its close homolog, Sec12p, is involved in vesicle formation at the ER
YKL198C PTK1 0.87 0.9 Putative serine/threonine protein kinase
YAL041W CDC24 0.87 1.2 calcium-binding protein involved in bud emergence and schmooing
YJL051W 0.87 6.1 Z S C Protein of unknown function
YDR285W ZIP1 0.87 2.0 Synaptonemal complex protein, component of the central element
YGR166W KRE11 0.87 1.1 Involved in biosynthetic pathway for cell wall beta-glucans
YKR005C 0.87 1.6 Protein of unknown function
YNL002C RLP7 0.87 1.6 Significant sequence similarity to RPL7B, but neither can functionally replace the other. Does not correspond to any ribosomal component identified so far, based o
YOR359W VTS1 0.87 1.1 vti1-2 suppressor
YPL066W 0.87 1.4 C Protein of unknown function
YMR081C ISF1 0.87 1.2 May regulate NAM7 function, possibly at level of mRNA turnover
YDR116C 0.87 1.7 Protein of unknown function
YCR048W ARE1 0.87 1.9 Acyl-CoA cholesterol acyltransferase (sterol-ester synthetase)
YOL100W PKH2 0.87 1.9 Pkb-activating Kinase Homologue
YDL179W PCL9 0.86 1.9 K S C PHO85 cyclin
YER064C 0.86 1.9 Protein of unknown function
YKL011C CCE1 0.86 1.8 cruciform cutting endonuclease
YJL215C 0.86 2.6 Protein of unknown function
YLR409C UTP21 0.86 1.1 Protein required for cell viability
YAL028W 0.86 2.1 Protein of unknown function
YGR283C 0.86 1.3 Protein of unknown function
h the Pry2p & Pry3p over 145 resid. PRY1 is >35% identical (50% similar) to tobacco PR-1c protein.
gene is downregulated at acidic pH.
s along the chromosome.
meases.
fied so far, based on its biochemical features