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11
INTERNATIONAL LEAGUE AGAINST EPILEPSY (ILAE)

Commission on European Affairs (CEA)



October 9, 2011



Chair : Ms. Astrid Krag

Professor Meir Bialer The Danish Minister of Health

Jerusalem, Israel

meirb@ekmd.huji.ac.il



Secretary: Your Excellence Minister Krag ,

Professor Alla Guekht

Moscow, Russia It is with great concern that the Commission on European Affairs (CEA) of

Professor Alexis

International League Against Epilepsy (ILAE) has received the news about the

Arzimanoglou impending closure of Dianalund Epilepsy Hospital, the only Epilepsy Centre in

Lyon, France Denmark. We are concerned because epilepsy is such a varied condition that any

well-functioning system of epilepsy care needs to be hierarchical and include a

Professor Michel Baulac highest-level reference centre to take care of the most difficult cases and provide

Paris, France

facilities also for selected groups of patients. These include in the diagnostic field

Professor Thnos Covanis prolonged combined video and EEG registrations, specialized neuropsychological

Athens, Greece investigations and evaluation programmes for the selection for epilepsy surgery,

including special imaging approaches such as ictal SPECT. In the therapeutic

Professor Helen Cross field, the highest level centres provide care for multiple handicapped persons and

London, UK

for patients with non-epileptic psychogenic and other seizures; they also offer

Professor Reetta

vagus nerve and other brain stimulation therapies as well as ketogenic diet for

Kalviainen children with intractable seizures. For several of these, the Dianalund Hospital is

Kuopio, Finland the only place in Denmark where they are available.

Professor Salomon Moshe It is generally assumed that in an adequate health system one highest level

New York, USA

epilepsy centre needs to be available for a population of 4 to 5 million inhabitants,

Professor Emilio Perucca about the population of Denmark. We understand that the present situation is due

Pavia, Italy to changes in your health care system where five regions take responsibility for

their population. It is, however, unrealistic to assume that expertise and facilities

Professor Asla Pitkanen for highest level epilepsy care can be built up in parallel for 5 subpopulations of

Kuopio, Finland

about 1 million each; in addition, such a system would not be cost-effective.

Professor Torbjorn

Tomson

Stockholm, Sweden



Professor Eugen Trinka

Innsbruck, Austria







ILAE Chapter Services Office

7 Priory Hall, Stillorgan, Co. Dublin, Ireland

Ph: +353 1 278 4908

Fax: +353 1 205 6156

www.ilae.org

INTERNATIONAL LEAGUE AGAINST EPILEPSY (ILAE)

Commission on European Affairs (CEA)





In addition to its role in the national health care for your country, the Danish

Epilepsy Centre has also developed into an active and increasingly prolific

Chair : research institution of excellent international renown whose contributions to the

Professor Meir Bialer scientific progress in epileptology would be greatly missed if the Centre

Jerusalem, Israel disappeared.

meirb@ekmd.huji.ac.il



Secretary: For all these reasons, we urgently ask you to ensure the continuous existence and

Professor Alla Guekht activity of the Danish Epilepsy Centre.

Moscow, Russia



Professor Alexis

Arzimanoglou

Lyon, France



Professor Michel Baulac

Paris, France



Professor Thnos Covanis Meir Bialer, Ph.D., M.B.A., CEA Chair

Athens, Greece David H. Eisenberg Professor of Pharmacy

School of Pharmacy

Professor Helen Cross Faculty of Medicine

London, UK The Hebrew University of Jerusalem

Jerusalem 91120, Israel

Professor Reetta

Kalviainen Tel:972-2-6758610 (work)

Kuopio, Finland Tel: 972-2-6522405 or 972-2-6520902 (home)

Fax: 972-2-6757246 or 972-26784010

Professor Salomon Moshe

New York, USA



Professor Emilio Perucca

Pavia, Italy



Professor Asla Pitkanen

Kuopio, Finland



Professor Torbjorn

Tomson

Stockholm, Sweden



Professor Eugen Trinka

Innsbruck, Austria



ILAE Chapter Services Office

7 Priory Hall, Stillorgan, Co. Dublin, Ireland

Ph: +353 1 278 4908

Fax: +353 1 205 6156

www.ilae.org

UFSC

Universidade Federal de Santa Catarina

Centro de Ciências da Saúde - Departamento de Clínica Médica

Campus Universitário - Trindade - Florianópolis-SC





Florianópolis, 10 de outubro de 2011.



To:

The Danish Minister of Health, Ms Astrid Krag,

The Folketingets Sundhedsudvalg, Denrnark



On behalf of the Neurology Section of the University Hospital, Federal University of Santa Catarina,

Florianópolis, SC, Brazil, we are writing to you regarding the Epilepsy Hospital in Dianalund.



It is with great surprise and concem that we took knowledge that the Epilepsy Hospital in Dianalund is

threatened due to reorganization of the Danish health care system. The Epilepsy Hospital in Dianalund is an

outstanding epilepsy centre among others in the world and its activities have been influencing greatly to

improve the quality of life of the people with epilepsy worldwide, promoting exchange of knowledge with

developing countries such as Brazil. The treatment and care for the people affected by epilepsy can only be

achieved successfully by a system comprehensively organized and coordinated by epilepsy centre(s).

Dianalund Epilepsy Centre is the on1y centre providing comprehensive diagnostics, treatment and care for

people with epilepsy in Denrnark.



Dianalund is also an important centre for intemational epilepsy research. An intemational research

consortium for the investigation of the provocative and inhibitory roles of sensory and cognitive stimuli in

the development of epileptic seizures was initiated two years ago, leaded by the Danish Epilepsy Centre, and

involved many researchers from various countries in the world, including uso As the first reports of this

collaboration, four presentations at the Intemational Epilepsy Congress in Rome this year, and the first

results have already been submitted for publication and diverse sub-projects are being developed since then.

The Danish Epilepsy Centre has a very important role in coordinating the various projects in this consortium

and providing methodological advices. Without the continuous input from Dianalund this entire promising

research initiative would fall apart.



Moreover, Prof. Dr. Peter Wolfis one ofthe most relevant scientists in the field ofEpilepsy worldwide. He

has made enormous contributions both in research and education, addressing epileptology at a level of

excellence. Just as an example of his recognized activities, he has conducted the Intemational League

against Epilepsy as President during a recent and very fruitful period.



We therefore very kindly ask you in the interest ofthe people with epilepsy and important research activities

in this field to take the necessary steps to save the existence of the Danish Epilepsy Centre as an

irreplaceable epilepsy centre in Denrnark.



Yours respectfully,



---~

Assistant Professor ofNeurology - Neurology Section

University Hospital- Federal University of Santa Catarina

To:

The Danish Minister of Health, Ms Astrid Krag,

The Folketingets Sundhedsudvalg, Denmark



Shizuoka, October 8, 2011



It is with great concern that we have heard that the Epilepsy Hospital in Dianalund is

threatened by closure due to reorganizations in the Danish health care system.



The Epilepsy Hospital in Dianalund is one of the best epilepsy centres in the world and its

activities have been influencing greatly to the movements to improve the quality of life of the

people with epilepsy worldwide, even of the far east country Japan. The treatment and care for

the people affected by epilepsy can only be achieved successfully by a system

comprehensively organized and coordinated by epilepsy centre(s). Dianalund Epilepsy Centre

is the only centre providing comprehensive diagnostics, treatment and care for people with

epilepsy in Denmark, and is therefore irreplaceable.



In addition to the central role in the treatment and care for people with epilepsy in Denmark,

Dianalund is also an important centre for international epilepsy research.

We are investigating the provocative and inhibitory roles of sensory and cognitive stimuli in

the development of epileptic seizures. This research was initiated two years ago from the

Danish Epilepsy Centre, and involved many researchers from various countries in the world,

including us. This international research consortium has already had four presentations of

results of this project at the International Epilepsy Congress in Rome this year, and a first

research publication has been submitted for publication. Several more sub-projects are being

developed. The Danish Epilepsy Centre has a very important role in coordinating the various

projects in this consortium and providing methodological advices. Without the continuous

input from Dianalund this entire promising research initiative would fall apart.



We therefore very kindly ask you in the interest of the people with epilepsy and important

research activities in this field to take the necessary steps to save the existence of the Danish

Epilepsy Centre as an irreplaceable epilepsy centre in Denmark and as an important

contributor to international epilepsy research.









Yushi Inoue, M.D., Ph.D.

Director, National Epilepsy Centre

Shizuoka Institute of Epilepsy and Neurological Disorders, Japan

Dr Mamta Bhushan Singh DEPARTMENT OF NEUROLOGY

M.D(Med), D.M(Neurology) NEUROSCIENCES CENTRE

Associate Professor & Co-In-charge ALL INDIA INSTITUTE OF MEDICAL SCIENCES

Clinical Neurophysiology Ansari Nagar, New Delhi – 110029 (India)

Tel.: Office: 26588500, 26588700 Extn: 4872

Fax: 91–11– 26588663

Email: mbsneuro@gmail.com







To: The Danish Minister of Health, Ms Astrid Krag and

Folketingets Sundhedsudvalg



Dear Minister and Members of the Folketingets Sundhedsudvalg,

Greetings from New Delhi, India. 7th October 2011



I am a neurologist from India and have had an association of more than two years now with colleagues from the

Epilepsy Centre in Dianalund, Denmark. I wish I was writing to you under happier circumstances but that is not

the case. My close association with my Dianalund colleagues has kept me following the news about the Epilepsy

Centre very closely. Just yesterday I got to know that there is a very real possibility of the Epilepsy Centre being

closed down. This information has made me anxious and concerned enough to write and make an appeal to all of

you.





I know that the Epilepsy Centre at Dianalund is a historical landmark providing state-of-the-art epilepsy care for

many decades in your country. However, the Centre for me is not just a service facility but a very important

epilepsy research centre too. I am a part of an International research consortium of which the Danish Centre too is

a part. In fact, the Danish Centre has spearheaded this International consortium providing exemplary leadership,

research guidance and coordination to all of us who come from a very diverse group from many different

countries. The role of the Danish Centre is central to the success of our consortium and this has already started to

manifest with as many as four research presentations already having been presented in a very prestigious

International meeting recently held at Rome. Many more projects are currently under way and many research

publications likely to emerge from ongoing projects.





On a more personal note, I would add that the Epilepsy Centre has exceeded its’ brief beyond its Epilepsy care

provider and Research Centre roles to being an excellent Ambassador of Goodwill on behalf of Denmark. Coming

from India and being a relatively junior neurologist, I might have never got the opportunity and guidance that the

Danish Centre colleagues have continuously provided to me and others like me. It is because of them that many of

us are encouraged and inspired to work in a more focussed and dedicated manner towards epilepsy research. We

will always hold our Danish colleagues and their Centre in great regard.

I appeal to your kind offices and am confident that you will make the best decision in your wisdom keeping in

mind the enormous impact that the Epilepsy Centre has had and continues to have on epilepsy research and care.



Regards,

Mamta Bhushan Singh,

Dept of Neurology,

All India Institute of Medical Sciences,

New Delhi, India

UFSC

Universidade Federal de Santa Catarina

Centro de Ciências da Saúde - Departamento de Clínica Médica

Campus Universitário - Trindade – Florianópolis – SC - Brazil





Florianópolis, 07 October, 2011.







To Astrid Krag

The Danish Minister of Health







It is with great concern that our group from the Epilepsy Center for Santa Catarina Sate (CEPESC, Florianópolis,



Brazil) we have informed that the Epilepsy Hospital in Dianalund, Denmark’s only Epilepsy Centre, is threatened by



closure due to reorganizations in the Danish health care system. We understand that apart from the Centre’s role in the



diagnostics and treatment for people with epilepsy in Denmark, Dianalund is an important centre for international



epilepsy research.



Our centre (CEPESC) is a very new, (started in 2008) and we received a scientific support from the Epilepsy Hospital



in Dianalund because two of our research fellows stayed there for a research project. We participate in the international



research consortium that is investigating the provocative and inhibitory roles of sensory and cognitive stimuli in the



development of epileptic seizures. This research was initiated two years ago from the Danish Epilepsy Centre, and at the



International Epilepsy Congress in Rome this year, the consortium has already had four presentations of results of this



project, and a first research publication has been submitted for publication. Several more sub-projects are being



developed. The Danish Epilepsy Centre is an important for coordinating the various projects in this consortium and



providing methodological advice. Without the continuous input from Dianalund this entire promising research will stop.



We, from the CEPESC epilepsy center (Florianópolis, Brazil) want to ask you to help to save the existence of the Danish



Epilepsy Centre as an important partner to international epilepsy research.









Professor of Internal Medicine Department

Federal University of Santa Catarina

and

Head of the Center of Epilepsy of Santa Catarina (CEPESC)

Secretary of Health of Santa Catarina State

Florianópolis, Santa Catarina, Brazil

Til

Sundhedsminister Astrid Krag

Folketingets Sundhedsudvalg

Epilepsihospitalet i Dianalund





Dansk Selskab for Klinisk Neurofysiologi ser med stor bekymring på meddelelsen om nedskæring af aktiviteten på

Epilepsihospitalet i Dianalund.

Epilepsihospitalet i Dianalund varetager bl.a. undersøgelse af epilepsipatienter med specielt komplicerede

diagnostiske problemstillinger og patienter hvis korrekte udredning og behandling kræver speciel høj ekspertise og

indsigt.

En lukning af hospitalet vil derfor have alvorlige konsekvenser for patienter med epilepsi, som er meget vanskelig at

diagnosticere og/eller behandle. Derudover foregår der en betydelig forskning og udvikling indenfor det

neurofysiologiske område på Epilepsihospitalet, specielt indenfor epilepsi, og Epilepsihospitalet i Dianalund bidrager

væsentligt til uddannelsen af neurologer, der ønsker at specialisere sig inden for epilepsi-området.

Epilepsihospitalet er derudover den eneste fuldt fungerende neurofysiologiske afdeling i Region Sjælland. En lukning

vil derfor medføre længere ventetider for patienter i Region Sjælland, som har brug for neurofysiologiske

undersøgelser i almindelighed.

Dansk Selskab for Klinisk Neurofysiologi skal derfor opfordre til at man overvejer om man i regionerne eller regeringen

man finde de økonomiske midler til at føre Epilepsihospitalet videre, da en lukning af hospitalet vil have store og

negative konsekvenser for patienter, hvis udredning og behandling kræver helt speciel ekspertise og erfaring indenfor

epileptologi.





På Dansk Selskab for Klinisk Neurofysiologis vegne









Benedikte Wanscher

Ledende overlæge, ph.d.

Formand for Dansk Selskab for Klinisk Neurofysiologi

http://dskn.dk

Klinisk Neurofysiologisk Afdeling

Glostrup Hospital

Nordre Ringevej

2600 Glostrup

telefon 3863 2567

mail: bewa01@glo.regionh.dk

6. oktober 2011





Til

Sundhedsminister

Astrid Krag





Vedr. nedskæringer på Epilepsihospitalet Filadelfia i Dianalund.



På vegne af Dansk Epilepsi Selskab skal vi hermed udtrykke stor bekymring over den aktuelle

situation på Epilepsihospitalet Filadelfia, hvor to specialafdelinger er blevet lukket og patienter

ikke kan modtages til behandling resten af året.



Vi ser os i den anledning nødsaget til at gøre opmærksom på, at en eventuel reduktion eller ophør

af Epilepsihospitalets bidrag til varetagelse af epilepsibehandlingen i Danmark, vil medføre en

betydelig forringelse af det samlede behandlingstilbud til især de hårdest ramte patienter med

epilepsi.



Dette skyldes følgende:



• Der er 35.000 – 40.000 patienter med epilepsi i Danmark. Heraf har 10.000 – 12.500 patienter

svær epilepsi, som i reglen er en invaliderende tilstand, der ledsages af væsentlige psyko-

sociale belastninger, både for patienten og dennes familie. Epilepsihospitalet Filadelfia har

gennem mange år varetaget ca. 15 % af den samlede epilepsibehandling i Danmark. På grund

af hospitalets særlige specialisering er det overvejende patienter med svær epilepsi, der

behandles på Epilepsihospitalet, hvilket betyder, at Filadelfia skønnes at varetage behandlingen

af ca. halvdelen af de hårdest ramte patienter med epilepsi i Danmark.



• Med lukning af specialafdelingerne for patienter med vidtgående fysisk og psykisk

udviklingshæmning ”Havehuset” og ”Ungdomsafdelingen” vil man miste landets eneste

mulighed for længerevarende indlæggelse til observation og behandling / rehabilitering af

patienter med særlige behov. Patienter, som er fysisk og psykisk udviklingshæmmede tilhører

den gruppe af epilepsipatienter, som er hårdest ramt og kan kun vanskeligt behandles under

indlæggelse i det øvrige hospitalssystem, der generelt ikke er velegnet til at rumme denne

opgave. Lukning af disse specialafdelinger vil således medføre, at epilepsibehandlingen i

Danmark langt overvejende fremover alene vil kunne omfatte ambulant behandling. Dette vil

betyde en væsentlig forringelse af det aktuelle behandlingstilbud.



• Epilepsihospitalet Filadelfia har, som det eneste sted i Danmark foruden Rigshospitalet, højt

specialiseret funktion til undersøgelse af mulighederne for kirurgisk behandling af epilepsi. I

tilfælde af reduktion i Epilepsihospitalets funktion vil kapaciteten til denne specialopgave

reduceres væsentligt, medmindre tilsvarende ressourcer overføres til andre steder i

hospitalsvæsnet. Alternativt skal patienterne sendes til udlandet for at modtage denne højt

specialiserede behandling.



• Personalet på Epilepsihospitalet Filadelfia har igennem årtier oparbejdet en uvurderlig praktisk

og videnskabelig erfaring og varetager aktuelt omfattende undervisningsopgaver, som blandt

andet indgår i specialistuddannelse af læger og sygeplejersker. En reduktion og splittelse af

denne vidensbank vil utvivlsomt medføre en forringelse af efteruddannelseskapaciteten inden

for epilepsispecialet i Danmark.

• Epilepsihospitalet har endvidere oparbejdet et højt kvalificeret forskningsmiljø og har opnået

forskningsresultater, der er anerkendt på et internationalt niveau.



Set ud fra et lægefagligt synspunkt er der således ingen tvivl om, at en reduktion i

Epilepsihospitalets funktion vil være et stort tab for epilepsibehandlingen i Danmark og vil

medføre tab af vigtig viden, forsknings- og uddannelseskompetence.





Kopi af brevet er sendt til Danske Regioner





På bestyrelsens vegne, med venlig hilsen





Anne Sabers, overlæge dr. med.

Formand for Dansk Epilepsi Selskab

Epilepsiklinikken, Neurologisk Afdeling

Rigshospitalet, Blegdamsvej 9

2100 Kbh Ø

Tlf: 22463258 / 35458097

E-mail: anne.sabers@rh.regionh.dk / a@sabers.dk


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